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Illumina Body Map 2 (GSE30611)
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Results for EP300
Z-value: 1.27
Motif logo
Transcription factors associated with EP300
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
EP300
|
ENSG00000100393.14 | E1A binding protein p300 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| EP300 | hg38_v1_chr22_+_41092869_41093005 | -0.14 | 4.3e-01 | Click! |
Activity profile of EP300 motif
Sorted Z-values of EP300 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of EP300
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.9 | GO:0031448 | regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) |
| 1.4 | 5.4 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 1.3 | 3.8 | GO:1901876 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 1.1 | 1.1 | GO:1904933 | regulation of cell proliferation in midbrain(GO:1904933) |
| 0.8 | 2.3 | GO:1902598 | creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598) |
| 0.7 | 2.1 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
| 0.6 | 5.7 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 0.6 | 4.4 | GO:0030421 | defecation(GO:0030421) |
| 0.5 | 6.9 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.5 | 1.6 | GO:0099538 | synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) |
| 0.5 | 1.5 | GO:0000412 | histone peptidyl-prolyl isomerization(GO:0000412) |
| 0.5 | 6.3 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 0.4 | 2.9 | GO:0014859 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 0.4 | 1.7 | GO:0097252 | oligodendrocyte apoptotic process(GO:0097252) |
| 0.4 | 4.2 | GO:0042695 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
| 0.4 | 0.7 | GO:0032304 | negative regulation of icosanoid secretion(GO:0032304) |
| 0.4 | 1.5 | GO:0018106 | peptidyl-histidine phosphorylation(GO:0018106) |
| 0.3 | 3.4 | GO:0014718 | positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) |
| 0.3 | 2.3 | GO:0060356 | leucine import(GO:0060356) |
| 0.3 | 1.5 | GO:0035106 | operant conditioning(GO:0035106) |
| 0.3 | 2.3 | GO:0044375 | peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375) |
| 0.3 | 1.1 | GO:1903939 | regulation of TORC2 signaling(GO:1903939) |
| 0.3 | 3.9 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.3 | 1.9 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 0.3 | 1.8 | GO:0097461 | endosome localization(GO:0032439) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.3 | 0.8 | GO:0010512 | negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) |
| 0.2 | 0.7 | GO:0046338 | phosphatidylethanolamine catabolic process(GO:0046338) |
| 0.2 | 0.7 | GO:1903572 | regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572) |
| 0.2 | 0.9 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.2 | 0.9 | GO:0022007 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 0.2 | 0.9 | GO:0051795 | positive regulation of catagen(GO:0051795) |
| 0.2 | 0.7 | GO:0051808 | translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836) |
| 0.2 | 1.5 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 0.2 | 0.6 | GO:2000562 | negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) |
| 0.2 | 2.1 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.2 | 0.8 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 0.2 | 2.0 | GO:0043129 | surfactant homeostasis(GO:0043129) |
| 0.2 | 1.3 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.2 | 2.2 | GO:0003190 | atrioventricular valve formation(GO:0003190) |
| 0.2 | 0.9 | GO:0019249 | lactate biosynthetic process(GO:0019249) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920) |
| 0.2 | 1.7 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.2 | 1.8 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.2 | 0.9 | GO:0097676 | histone H3-K36 dimethylation(GO:0097676) |
| 0.2 | 0.9 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
| 0.2 | 1.9 | GO:0070120 | ciliary neurotrophic factor-mediated signaling pathway(GO:0070120) |
| 0.2 | 2.2 | GO:0009414 | response to water deprivation(GO:0009414) |
| 0.2 | 1.9 | GO:0030578 | PML body organization(GO:0030578) |
| 0.2 | 0.8 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.2 | 3.3 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
| 0.2 | 1.1 | GO:2000535 | regulation of entry of bacterium into host cell(GO:2000535) |
| 0.1 | 2.3 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.1 | 0.6 | GO:0090071 | negative regulation of ribosome biogenesis(GO:0090071) |
| 0.1 | 0.5 | GO:0006550 | isoleucine catabolic process(GO:0006550) |
| 0.1 | 0.5 | GO:0034628 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 0.1 | 0.4 | GO:0018315 | molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579) |
| 0.1 | 2.2 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.1 | 1.2 | GO:2000580 | regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.1 | 2.0 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 0.1 | 0.5 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.1 | 2.1 | GO:0035791 | platelet-derived growth factor receptor-beta signaling pathway(GO:0035791) |
| 0.1 | 0.6 | GO:1904222 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
| 0.1 | 1.7 | GO:1901725 | regulation of histone deacetylase activity(GO:1901725) |
| 0.1 | 1.3 | GO:0030091 | protein repair(GO:0030091) |
| 0.1 | 1.2 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.1 | 1.0 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.1 | 1.7 | GO:1901750 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.1 | 0.7 | GO:0010481 | epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) |
| 0.1 | 4.5 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.1 | 2.4 | GO:0031268 | pseudopodium organization(GO:0031268) |
| 0.1 | 0.4 | GO:0046882 | negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882) |
| 0.1 | 0.6 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 0.1 | 1.5 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.1 | 1.1 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 0.1 | 0.9 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.1 | 1.0 | GO:0033088 | negative regulation of immature T cell proliferation in thymus(GO:0033088) |
| 0.1 | 1.0 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.1 | 0.6 | GO:0051673 | membrane disruption in other organism(GO:0051673) |
| 0.1 | 0.2 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 0.1 | 0.9 | GO:0097647 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.1 | 1.4 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.1 | 0.5 | GO:0050925 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925) |
| 0.1 | 1.6 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 0.5 | GO:0072752 | cellular response to rapamycin(GO:0072752) |
| 0.1 | 0.5 | GO:0090669 | telomerase RNA stabilization(GO:0090669) |
| 0.1 | 1.0 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 0.1 | 1.4 | GO:0060137 | maternal process involved in parturition(GO:0060137) |
| 0.1 | 0.3 | GO:0090299 | regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
| 0.1 | 1.0 | GO:0061042 | vascular wound healing(GO:0061042) |
| 0.1 | 0.5 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
| 0.1 | 0.2 | GO:0014050 | negative regulation of glutamate secretion(GO:0014050) |
| 0.1 | 1.4 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.1 | 0.5 | GO:0090238 | positive regulation of gamma-aminobutyric acid secretion(GO:0014054) positive regulation of arachidonic acid secretion(GO:0090238) |
| 0.1 | 0.7 | GO:0030807 | positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) |
| 0.1 | 0.5 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.1 | 0.6 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
| 0.1 | 0.7 | GO:0097011 | cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012) |
| 0.1 | 0.8 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.1 | 0.6 | GO:0042791 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 0.1 | 0.5 | GO:0051415 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.1 | 0.6 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.1 | 0.9 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.1 | 1.4 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.1 | 2.5 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.1 | 0.3 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.1 | 0.9 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.1 | 0.4 | GO:1900827 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.0 | 0.8 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.0 | 0.5 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
| 0.0 | 0.9 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.0 | 0.7 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
| 0.0 | 2.2 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.0 | 0.4 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.0 | 0.4 | GO:0060087 | relaxation of vascular smooth muscle(GO:0060087) |
| 0.0 | 0.9 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
| 0.0 | 1.1 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.0 | 2.6 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.0 | 0.6 | GO:1901407 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) |
| 0.0 | 1.6 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.0 | 0.8 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.0 | 0.7 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 0.4 | GO:0035965 | cardiolipin acyl-chain remodeling(GO:0035965) |
| 0.0 | 3.3 | GO:0003254 | regulation of membrane depolarization(GO:0003254) |
| 0.0 | 0.3 | GO:0018406 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.0 | 0.1 | GO:2000399 | negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399) |
| 0.0 | 1.7 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.0 | 0.5 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.0 | 0.9 | GO:0036109 | alpha-linolenic acid metabolic process(GO:0036109) |
| 0.0 | 0.3 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.0 | 0.9 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.0 | 0.4 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
| 0.0 | 0.7 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.0 | 2.3 | GO:0009214 | cyclic nucleotide catabolic process(GO:0009214) |
| 0.0 | 0.6 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.0 | 0.3 | GO:0001712 | ectodermal cell fate commitment(GO:0001712) |
| 0.0 | 0.7 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 2.1 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.0 | 0.5 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.0 | 3.2 | GO:0048747 | muscle fiber development(GO:0048747) |
| 0.0 | 2.9 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 0.3 | GO:0042048 | olfactory behavior(GO:0042048) |
| 0.0 | 0.4 | GO:0015747 | urate transport(GO:0015747) |
| 0.0 | 0.3 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 0.0 | 0.1 | GO:0071931 | positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) |
| 0.0 | 1.1 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.0 | 3.0 | GO:0048701 | embryonic cranial skeleton morphogenesis(GO:0048701) |
| 0.0 | 0.3 | GO:0070257 | positive regulation of mucus secretion(GO:0070257) |
| 0.0 | 0.5 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.0 | 0.4 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.0 | 0.3 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.0 | 0.8 | GO:0006884 | cell volume homeostasis(GO:0006884) |
| 0.0 | 0.3 | GO:0017062 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) |
| 0.0 | 0.5 | GO:0048490 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.0 | 0.6 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.0 | 0.4 | GO:0015727 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
| 0.0 | 1.0 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.0 | 0.1 | GO:0008204 | ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) |
| 0.0 | 0.2 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.0 | 1.3 | GO:0008038 | neuron recognition(GO:0008038) |
| 0.0 | 1.9 | GO:0045540 | regulation of cholesterol biosynthetic process(GO:0045540) |
| 0.0 | 0.2 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.0 | 0.3 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.0 | 0.1 | GO:0048561 | establishment of organ orientation(GO:0048561) |
| 0.0 | 2.1 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.0 | 0.2 | GO:0032808 | lacrimal gland development(GO:0032808) |
| 0.0 | 0.2 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.0 | 0.1 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
| 0.0 | 0.5 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.0 | 2.5 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 2.1 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.0 | 0.2 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.0 | 1.4 | GO:0051693 | actin filament capping(GO:0051693) |
| 0.0 | 0.1 | GO:0006203 | dGTP catabolic process(GO:0006203) |
| 0.0 | 0.3 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.0 | 1.6 | GO:0032642 | regulation of chemokine production(GO:0032642) |
| 0.0 | 0.2 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.0 | 0.5 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.0 | 0.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 1.2 | GO:0007566 | embryo implantation(GO:0007566) |
| 0.0 | 1.2 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 0.3 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.0 | 0.4 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.0 | 0.6 | GO:0006349 | regulation of gene expression by genetic imprinting(GO:0006349) |
| 0.0 | 0.4 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 0.2 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.0 | 0.3 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.0 | 1.2 | GO:0042274 | ribosomal small subunit biogenesis(GO:0042274) |
| 0.0 | 0.4 | GO:1904707 | positive regulation of vascular smooth muscle cell proliferation(GO:1904707) |
| 0.0 | 0.2 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) |
| 0.0 | 0.5 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.0 | 0.1 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.0 | 0.7 | GO:0001755 | neural crest cell migration(GO:0001755) |
| 0.0 | 0.2 | GO:0006924 | activation-induced cell death of T cells(GO:0006924) |
| 0.0 | 0.4 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
| 0.0 | 0.1 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
| 0.0 | 0.5 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
| 0.0 | 0.2 | GO:0042354 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.0 | 0.9 | GO:0032410 | negative regulation of transporter activity(GO:0032410) |
| 0.0 | 0.7 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
| 0.0 | 0.3 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.0 | 0.1 | GO:0031087 | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.0 | 0.2 | GO:0097116 | postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.0 | 0.4 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.0 | 0.1 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
| 0.0 | 0.2 | GO:0060123 | regulation of growth hormone secretion(GO:0060123) positive regulation of growth hormone secretion(GO:0060124) regulation of GTP binding(GO:1904424) |
| 0.0 | 0.2 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.6 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.4 | 1.9 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 0.3 | 3.0 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.3 | 1.4 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.3 | 5.5 | GO:0005861 | troponin complex(GO:0005861) |
| 0.2 | 1.7 | GO:1990393 | 3M complex(GO:1990393) |
| 0.2 | 1.9 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.2 | 1.6 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.2 | 1.9 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.2 | 1.9 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.2 | 1.8 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.2 | 2.0 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.1 | 5.4 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.1 | 3.9 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.1 | 0.8 | GO:0072589 | box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 0.1 | 1.4 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.1 | 1.1 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.1 | 1.1 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 0.1 | 0.9 | GO:1903439 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 0.1 | 4.0 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 1.3 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.1 | 2.1 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.1 | 0.2 | GO:1990716 | axonemal central apparatus(GO:1990716) |
| 0.1 | 1.5 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 11.4 | GO:0016528 | sarcoplasm(GO:0016528) |
| 0.1 | 0.9 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 1.0 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.1 | 0.5 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.1 | 2.0 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 2.3 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.1 | 1.4 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 0.6 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.1 | 0.5 | GO:0032021 | NELF complex(GO:0032021) |
| 0.1 | 0.5 | GO:0000923 | equatorial microtubule organizing center(GO:0000923) |
| 0.1 | 1.5 | GO:0036038 | MKS complex(GO:0036038) |
| 0.1 | 0.7 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.1 | 1.8 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.1 | 0.2 | GO:0098984 | neuron to neuron synapse(GO:0098984) |
| 0.0 | 2.0 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 9.8 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 2.0 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.7 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.0 | 1.1 | GO:0005845 | mRNA cap binding complex(GO:0005845) |
| 0.0 | 2.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.5 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.0 | 1.0 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.7 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.0 | 4.1 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.4 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.0 | 1.2 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.0 | 3.1 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 1.2 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.3 | GO:0031523 | Myb complex(GO:0031523) |
| 0.0 | 0.9 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 0.5 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.0 | 1.2 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 0.3 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.0 | 6.6 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.1 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.0 | 3.2 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.5 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 2.0 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 2.8 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.2 | GO:1990745 | EARP complex(GO:1990745) |
| 0.0 | 0.4 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.3 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.0 | 0.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.6 | GO:0030904 | retromer complex(GO:0030904) |
| 0.0 | 0.3 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 1.2 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.2 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.0 | 0.9 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 0.3 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 1.9 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 0.2 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.0 | 1.1 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.1 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.0 | 1.8 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 2.6 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.3 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.0 | 1.2 | GO:0031903 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 2.0 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 2.3 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 3.9 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 0.1 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.0 | 0.2 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.0 | 0.1 | GO:0000796 | condensin complex(GO:0000796) |
| 0.0 | 2.1 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.9 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.3 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 0.3 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 0.4 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.0 | 0.2 | GO:0045180 | basal cortex(GO:0045180) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 6.3 | GO:0031751 | D4 dopamine receptor binding(GO:0031751) |
| 1.0 | 4.0 | GO:0008184 | glycogen phosphorylase activity(GO:0008184) |
| 0.8 | 2.3 | GO:0005308 | creatine transmembrane transporter activity(GO:0005308) |
| 0.6 | 3.9 | GO:0016900 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 0.6 | 1.7 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
| 0.5 | 2.1 | GO:0005019 | platelet-derived growth factor beta-receptor activity(GO:0005019) |
| 0.5 | 1.6 | GO:0060175 | brain-derived neurotrophic factor-activated receptor activity(GO:0060175) |
| 0.5 | 1.5 | GO:0016497 | substance K receptor activity(GO:0016497) |
| 0.4 | 6.0 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.4 | 2.1 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 0.3 | 1.3 | GO:0004113 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113) |
| 0.3 | 1.2 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
| 0.3 | 0.9 | GO:0004615 | phosphomannomutase activity(GO:0004615) |
| 0.3 | 0.8 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.2 | 1.4 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.2 | 1.9 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.2 | 1.2 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.2 | 2.7 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.2 | 3.0 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.2 | 1.6 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.2 | 1.7 | GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) |
| 0.2 | 1.9 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.2 | 5.1 | GO:0031432 | titin binding(GO:0031432) |
| 0.2 | 1.5 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.2 | 2.3 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.1 | 0.4 | GO:0070975 | FHA domain binding(GO:0070975) |
| 0.1 | 1.5 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
| 0.1 | 1.3 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.1 | 0.7 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.1 | 1.1 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.1 | 6.2 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.1 | 4.9 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.9 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.1 | 0.5 | GO:0000309 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) |
| 0.1 | 0.4 | GO:0061599 | nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599) |
| 0.1 | 1.0 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.1 | 0.9 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 0.1 | 2.1 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.1 | 0.5 | GO:0052655 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.1 | 0.4 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
| 0.1 | 1.6 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.1 | 0.8 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.1 | 1.5 | GO:0004673 | protein histidine kinase activity(GO:0004673) |
| 0.1 | 1.7 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.1 | 1.0 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.1 | 0.9 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 1.1 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.1 | 1.2 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.1 | 2.1 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 1.4 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.1 | 0.9 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.1 | 0.4 | GO:0001512 | dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408) |
| 0.1 | 0.2 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
| 0.1 | 0.9 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.1 | 0.9 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.1 | 1.2 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.1 | 0.4 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.1 | 2.7 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.1 | 0.5 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 0.1 | 1.6 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.1 | 0.5 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.1 | 0.8 | GO:0050694 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.1 | 0.4 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.1 | 3.3 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.1 | 0.7 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.1 | 0.7 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 1.5 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 2.6 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.1 | 2.1 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 0.3 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.0 | 0.6 | GO:0010851 | cyclase regulator activity(GO:0010851) |
| 0.0 | 0.9 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.0 | 1.4 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.0 | 1.5 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.8 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.0 | 13.2 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 3.0 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 3.3 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.5 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.0 | 2.6 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.3 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.0 | 1.6 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.6 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.0 | 1.9 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.4 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.0 | 0.1 | GO:0008413 | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539) |
| 0.0 | 0.5 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.0 | 3.8 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.5 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
| 0.0 | 0.9 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 2.0 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 1.0 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 0.3 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.0 | 0.4 | GO:0045182 | translation regulator activity(GO:0045182) |
| 0.0 | 1.0 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.0 | 0.6 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 1.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.6 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.0 | 0.4 | GO:1901702 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.0 | 1.1 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.3 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.0 | 0.3 | GO:0043139 | 5'-3' DNA helicase activity(GO:0043139) |
| 0.0 | 6.6 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.0 | 0.4 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.0 | 0.3 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.1 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.0 | 0.8 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 0.6 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.0 | 5.2 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 0.4 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.1 | GO:0004310 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
| 0.0 | 0.6 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 0.1 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 0.0 | 0.4 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.0 | 1.2 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.7 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.0 | 0.6 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 0.2 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.0 | 0.4 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.0 | 0.5 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.5 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 0.2 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.0 | 1.4 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 1.4 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 3.7 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.7 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 0.6 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.0 | 0.4 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.4 | GO:0016505 | peptidase activator activity involved in apoptotic process(GO:0016505) |
| 0.0 | 0.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.1 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.0 | 1.6 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 4.8 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.0 | 0.7 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.4 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.0 | 1.2 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.0 | 0.3 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 0.6 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 0.5 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.0 | 0.5 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 1.3 | GO:0005179 | hormone activity(GO:0005179) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.1 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.1 | 6.6 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.1 | 5.2 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 2.0 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.1 | 5.6 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 1.0 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.1 | 4.6 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 0.9 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.1 | 5.5 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 2.8 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 1.1 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 1.7 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 2.2 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 2.1 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.9 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 2.2 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 2.2 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.0 | 2.1 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 1.2 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 1.2 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.7 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.0 | 0.8 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.0 | 0.7 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 3.1 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.7 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 2.0 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 6.2 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.4 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 0.6 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.4 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 0.5 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 0.5 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.6 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 4.5 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.1 | 5.2 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.1 | 8.0 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 5.2 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 5.4 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.1 | 6.4 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 2.1 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 5.5 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 0.8 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.1 | 2.0 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 2.2 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.1 | 2.8 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.0 | 0.6 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 2.0 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 1.9 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 0.8 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 1.6 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 1.8 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.9 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 1.7 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 1.2 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 1.8 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 1.4 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.9 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 1.6 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 1.0 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.0 | 0.5 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 0.8 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.4 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 1.0 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 0.4 | REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION | Genes involved in Glucagon signaling in metabolic regulation |
| 0.0 | 0.8 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.0 | 0.5 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 3.1 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 0.5 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.4 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.0 | 0.5 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 1.3 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 2.4 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 2.7 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 0.4 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.3 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.0 | 0.3 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 2.9 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.0 | 0.9 | REACTOME SIGNALING BY PDGF | Genes involved in Signaling by PDGF |
| 0.0 | 0.2 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.0 | 0.4 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |