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Illumina Body Map 2 (GSE30611)
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Results for EPAS1_BCL3
Z-value: 2.20
Motif logo
Transcription factors associated with EPAS1_BCL3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
EPAS1
|
ENSG00000116016.14 | endothelial PAS domain protein 1 |
|
BCL3
|
ENSG00000069399.15 | BCL3 transcription coactivator |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BCL3 | hg38_v1_chr19_+_44751251_44751321 | -0.38 | 3.3e-02 | Click! |
| EPAS1 | hg38_v1_chr2_+_46297397_46297414 | 0.31 | 8.5e-02 | Click! |
Activity profile of EPAS1_BCL3 motif
Sorted Z-values of EPAS1_BCL3 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of EPAS1_BCL3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 11.7 | GO:1990926 | short-term synaptic potentiation(GO:1990926) |
| 1.9 | 5.7 | GO:0099538 | synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) |
| 1.7 | 12.0 | GO:0010732 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
| 1.7 | 5.1 | GO:0071206 | establishment of protein localization to juxtaparanode region of axon(GO:0071206) |
| 1.5 | 4.4 | GO:0072034 | renal vesicle induction(GO:0072034) |
| 1.4 | 5.7 | GO:0010902 | positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) |
| 1.4 | 4.2 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 1.3 | 21.5 | GO:0070444 | oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) |
| 1.2 | 10.6 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 1.2 | 10.5 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) |
| 1.0 | 8.3 | GO:0097327 | response to antineoplastic agent(GO:0097327) |
| 0.8 | 7.4 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.8 | 2.3 | GO:1903697 | negative regulation of microvillus assembly(GO:1903697) |
| 0.8 | 10.8 | GO:0060681 | branch elongation involved in ureteric bud branching(GO:0060681) |
| 0.8 | 2.3 | GO:1990172 | G-protein coupled receptor catabolic process(GO:1990172) |
| 0.8 | 2.3 | GO:0043397 | corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) |
| 0.7 | 3.0 | GO:0006710 | androgen catabolic process(GO:0006710) |
| 0.7 | 2.8 | GO:0098971 | anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) |
| 0.7 | 2.7 | GO:0018153 | isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262) |
| 0.7 | 2.6 | GO:1904616 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
| 0.6 | 11.5 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.6 | 7.4 | GO:0070560 | protein secretion by platelet(GO:0070560) |
| 0.6 | 1.9 | GO:0033341 | regulation of collagen binding(GO:0033341) |
| 0.6 | 1.8 | GO:0046271 | phenylpropanoid catabolic process(GO:0046271) |
| 0.6 | 6.5 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.6 | 2.9 | GO:0038098 | sequestering of BMP from receptor via BMP binding(GO:0038098) |
| 0.6 | 1.7 | GO:0006173 | dADP biosynthetic process(GO:0006173) |
| 0.6 | 8.9 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.5 | 1.6 | GO:0021758 | caudate nucleus development(GO:0021757) putamen development(GO:0021758) |
| 0.5 | 2.1 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 0.5 | 5.1 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.5 | 1.5 | GO:1905006 | negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006) |
| 0.5 | 3.5 | GO:0061528 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450) |
| 0.5 | 2.5 | GO:1903974 | mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141) |
| 0.5 | 2.4 | GO:0072675 | osteoclast fusion(GO:0072675) |
| 0.5 | 1.9 | GO:0006540 | glutamate decarboxylation to succinate(GO:0006540) |
| 0.5 | 1.0 | GO:0042940 | D-amino acid transport(GO:0042940) |
| 0.5 | 1.9 | GO:0060168 | positive regulation of adenosine receptor signaling pathway(GO:0060168) |
| 0.5 | 1.4 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099) |
| 0.5 | 3.3 | GO:0033563 | dorsal/ventral axon guidance(GO:0033563) |
| 0.5 | 1.8 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 0.4 | 1.7 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.4 | 9.1 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.4 | 5.5 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 0.4 | 1.7 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.4 | 1.2 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 0.4 | 5.7 | GO:1902866 | regulation of retina development in camera-type eye(GO:1902866) |
| 0.4 | 1.2 | GO:1902173 | negative regulation of keratinocyte apoptotic process(GO:1902173) |
| 0.4 | 1.1 | GO:0050760 | negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
| 0.4 | 1.1 | GO:0021793 | chemorepulsion of branchiomotor axon(GO:0021793) |
| 0.4 | 2.2 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.4 | 1.1 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 0.4 | 5.1 | GO:0035524 | proline transmembrane transport(GO:0035524) |
| 0.4 | 3.6 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 0.4 | 2.1 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 0.3 | 1.0 | GO:0052331 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
| 0.3 | 1.4 | GO:1904479 | negative regulation of intestinal absorption(GO:1904479) |
| 0.3 | 2.0 | GO:0018916 | nitrobenzene metabolic process(GO:0018916) |
| 0.3 | 4.7 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.3 | 11.0 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.3 | 1.3 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
| 0.3 | 7.0 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.3 | 0.9 | GO:0031550 | positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550) |
| 0.3 | 0.9 | GO:1904956 | regulation of midbrain dopaminergic neuron differentiation(GO:1904956) |
| 0.3 | 0.9 | GO:0042938 | dipeptide transport(GO:0042938) |
| 0.3 | 18.8 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.3 | 2.4 | GO:0097114 | NMDA glutamate receptor clustering(GO:0097114) |
| 0.3 | 3.0 | GO:0034371 | chylomicron remodeling(GO:0034371) |
| 0.3 | 1.5 | GO:0061026 | cardiac muscle tissue regeneration(GO:0061026) |
| 0.3 | 6.1 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.3 | 0.9 | GO:0051939 | gamma-aminobutyric acid import(GO:0051939) |
| 0.3 | 0.9 | GO:0071464 | cellular response to hydrostatic pressure(GO:0071464) |
| 0.3 | 6.3 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.3 | 0.8 | GO:0019878 | lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) |
| 0.3 | 0.8 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
| 0.3 | 3.1 | GO:2000582 | regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.3 | 2.9 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.3 | 1.0 | GO:2000360 | negative regulation of binding of sperm to zona pellucida(GO:2000360) |
| 0.3 | 0.8 | GO:1903570 | regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572) |
| 0.2 | 2.0 | GO:0071109 | superior temporal gyrus development(GO:0071109) |
| 0.2 | 0.7 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 0.2 | 3.9 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.2 | 1.4 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 0.2 | 0.7 | GO:0032289 | central nervous system myelin formation(GO:0032289) |
| 0.2 | 0.7 | GO:1990764 | regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
| 0.2 | 1.2 | GO:0019087 | transformation of host cell by virus(GO:0019087) |
| 0.2 | 3.7 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
| 0.2 | 2.9 | GO:0097107 | postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.2 | 3.4 | GO:0048711 | positive regulation of astrocyte differentiation(GO:0048711) |
| 0.2 | 9.1 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.2 | 5.7 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
| 0.2 | 0.9 | GO:0045226 | extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) |
| 0.2 | 0.6 | GO:0034443 | negative regulation of lipoprotein oxidation(GO:0034443) |
| 0.2 | 5.4 | GO:0044872 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.2 | 0.8 | GO:0046909 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
| 0.2 | 3.4 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.2 | 3.0 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
| 0.2 | 1.6 | GO:0060677 | ureteric bud elongation(GO:0060677) ureteric bud invasion(GO:0072092) |
| 0.2 | 9.0 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.2 | 1.2 | GO:0019464 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 0.2 | 1.0 | GO:0038169 | somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170) |
| 0.2 | 1.6 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.2 | 1.6 | GO:0072658 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.2 | 0.6 | GO:0034769 | basement membrane disassembly(GO:0034769) |
| 0.2 | 5.0 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.2 | 2.1 | GO:0097475 | motor neuron migration(GO:0097475) |
| 0.2 | 1.9 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
| 0.2 | 5.1 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.2 | 0.7 | GO:1900104 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
| 0.2 | 2.7 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
| 0.2 | 2.5 | GO:0055096 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
| 0.2 | 11.2 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.2 | 3.1 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.2 | 9.0 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.2 | 1.2 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.2 | 2.2 | GO:0071313 | cellular response to caffeine(GO:0071313) |
| 0.2 | 0.7 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 0.2 | 0.8 | GO:0030070 | insulin processing(GO:0030070) |
| 0.2 | 0.7 | GO:0036058 | filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) |
| 0.2 | 0.7 | GO:0045065 | cytotoxic T cell differentiation(GO:0045065) |
| 0.2 | 1.5 | GO:0097491 | sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) |
| 0.2 | 0.5 | GO:0098886 | modification of dendritic spine(GO:0098886) |
| 0.2 | 1.1 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 0.2 | 0.5 | GO:0099557 | trans-synaptic signaling by trans-synaptic complex(GO:0099545) trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557) |
| 0.2 | 2.9 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
| 0.2 | 8.6 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.2 | 0.8 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 0.2 | 1.3 | GO:1902613 | regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262) |
| 0.2 | 1.3 | GO:2001023 | regulation of response to drug(GO:2001023) |
| 0.2 | 1.3 | GO:2000490 | negative regulation of hepatic stellate cell activation(GO:2000490) |
| 0.2 | 1.6 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 0.2 | 2.5 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.2 | 1.1 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.2 | 0.3 | GO:0070093 | negative regulation of glucagon secretion(GO:0070093) somatostatin secretion(GO:0070253) |
| 0.2 | 1.5 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.1 | 1.2 | GO:1902998 | regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 0.1 | 1.8 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.1 | 1.3 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) |
| 0.1 | 1.4 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.1 | 0.6 | GO:0048691 | modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026) |
| 0.1 | 1.4 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.1 | 1.0 | GO:0071830 | chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) |
| 0.1 | 1.9 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 0.1 | 1.9 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 0.8 | GO:0034164 | negative regulation of toll-like receptor 9 signaling pathway(GO:0034164) |
| 0.1 | 0.6 | GO:1904045 | cellular response to aldosterone(GO:1904045) |
| 0.1 | 1.2 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.1 | 0.7 | GO:0014740 | negative regulation of muscle hyperplasia(GO:0014740) |
| 0.1 | 2.3 | GO:0035640 | exploration behavior(GO:0035640) |
| 0.1 | 1.2 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 0.1 | 0.4 | GO:1903248 | regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283) |
| 0.1 | 0.4 | GO:0043049 | hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
| 0.1 | 1.4 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.1 | 0.8 | GO:2000661 | positive regulation of interleukin-1-mediated signaling pathway(GO:2000661) |
| 0.1 | 0.5 | GO:2001226 | negative regulation of chloride transport(GO:2001226) |
| 0.1 | 2.8 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 2.2 | GO:0002029 | desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) |
| 0.1 | 2.1 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.1 | 2.1 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.1 | 1.3 | GO:0036371 | protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907) |
| 0.1 | 1.1 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.1 | 1.7 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.1 | 1.3 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.1 | 1.7 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.1 | 1.3 | GO:0003360 | brainstem development(GO:0003360) |
| 0.1 | 0.7 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.1 | 1.2 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.1 | 0.6 | GO:0009257 | 10-formyltetrahydrofolate biosynthetic process(GO:0009257) |
| 0.1 | 0.5 | GO:1903892 | negative regulation of ATF6-mediated unfolded protein response(GO:1903892) |
| 0.1 | 1.2 | GO:0042428 | serotonin metabolic process(GO:0042428) |
| 0.1 | 1.8 | GO:0098914 | membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) |
| 0.1 | 7.5 | GO:0014037 | Schwann cell differentiation(GO:0014037) |
| 0.1 | 2.1 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.1 | 0.8 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
| 0.1 | 3.4 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.1 | 0.3 | GO:0080120 | CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120) |
| 0.1 | 0.3 | GO:1903401 | lysine transport(GO:0015819) L-lysine transport(GO:1902022) L-lysine transmembrane transport(GO:1903401) |
| 0.1 | 0.7 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
| 0.1 | 2.5 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
| 0.1 | 0.3 | GO:0010511 | regulation of phosphatidylinositol biosynthetic process(GO:0010511) |
| 0.1 | 7.8 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.1 | 0.4 | GO:0019376 | galactolipid catabolic process(GO:0019376) |
| 0.1 | 0.3 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
| 0.1 | 0.8 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.1 | 0.1 | GO:1901420 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420) |
| 0.1 | 8.2 | GO:0060997 | dendritic spine morphogenesis(GO:0060997) |
| 0.1 | 0.5 | GO:0098915 | membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915) |
| 0.1 | 0.5 | GO:1904566 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 0.1 | 10.1 | GO:0032411 | positive regulation of transporter activity(GO:0032411) |
| 0.1 | 0.6 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.1 | 0.5 | GO:0010387 | COP9 signalosome assembly(GO:0010387) |
| 0.1 | 1.3 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 0.1 | 0.8 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 0.1 | 11.0 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.1 | 1.3 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.1 | 3.5 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
| 0.1 | 1.8 | GO:0090292 | nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.1 | 0.8 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.1 | 1.2 | GO:0006987 | activation of signaling protein activity involved in unfolded protein response(GO:0006987) |
| 0.1 | 0.9 | GO:0021562 | vestibulocochlear nerve development(GO:0021562) |
| 0.1 | 0.8 | GO:0060005 | vestibular reflex(GO:0060005) |
| 0.1 | 2.1 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.1 | 0.4 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
| 0.1 | 0.5 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 0.1 | 0.3 | GO:0051714 | negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714) |
| 0.1 | 0.7 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 0.1 | 4.3 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.1 | 0.7 | GO:0051415 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.1 | 1.7 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.1 | 2.3 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.1 | 0.3 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.1 | 0.3 | GO:0072144 | glomerular mesangial cell development(GO:0072144) |
| 0.1 | 2.0 | GO:1904152 | regulation of retrograde protein transport, ER to cytosol(GO:1904152) |
| 0.1 | 0.3 | GO:0018874 | benzoate metabolic process(GO:0018874) |
| 0.1 | 0.4 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
| 0.1 | 1.3 | GO:0035878 | nail development(GO:0035878) |
| 0.1 | 0.9 | GO:0042738 | exogenous drug catabolic process(GO:0042738) |
| 0.1 | 0.9 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
| 0.1 | 2.0 | GO:2000171 | negative regulation of dendrite development(GO:2000171) |
| 0.1 | 0.5 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 0.1 | 0.3 | GO:0044856 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906) |
| 0.1 | 1.2 | GO:0021681 | cerebellar granular layer development(GO:0021681) |
| 0.1 | 8.1 | GO:1901379 | regulation of potassium ion transmembrane transport(GO:1901379) |
| 0.1 | 1.4 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.1 | 1.8 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
| 0.1 | 1.7 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.1 | 1.1 | GO:1904903 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 0.1 | 1.3 | GO:0016322 | neuron remodeling(GO:0016322) |
| 0.1 | 0.3 | GO:0043091 | L-arginine import(GO:0043091) arginine import(GO:0090467) |
| 0.1 | 0.1 | GO:0003275 | apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) |
| 0.1 | 0.5 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
| 0.1 | 1.6 | GO:0045745 | positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745) |
| 0.1 | 0.6 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.1 | 2.4 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.1 | 2.3 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.1 | 0.2 | GO:0060262 | regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060) |
| 0.1 | 4.8 | GO:0007602 | phototransduction(GO:0007602) |
| 0.1 | 0.3 | GO:0060746 | maternal behavior(GO:0042711) parental behavior(GO:0060746) |
| 0.1 | 0.5 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.1 | 0.5 | GO:0070474 | positive regulation of uterine smooth muscle contraction(GO:0070474) |
| 0.1 | 1.0 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.1 | 0.2 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.1 | 1.2 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.1 | 0.4 | GO:0097461 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.1 | 1.4 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
| 0.1 | 0.3 | GO:1900369 | negative regulation of RNA interference(GO:1900369) |
| 0.1 | 6.2 | GO:1904590 | negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein import(GO:1904590) |
| 0.1 | 2.7 | GO:0014911 | positive regulation of smooth muscle cell migration(GO:0014911) |
| 0.1 | 0.6 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.1 | 0.4 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.1 | 0.6 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 0.1 | 1.1 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 0.1 | 0.4 | GO:0032960 | regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962) |
| 0.1 | 0.2 | GO:0070124 | mitochondrial translational initiation(GO:0070124) |
| 0.1 | 0.5 | GO:0060235 | voluntary musculoskeletal movement(GO:0050882) lens induction in camera-type eye(GO:0060235) |
| 0.1 | 0.3 | GO:0006050 | mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051) |
| 0.1 | 2.9 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.1 | 0.5 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.1 | 0.5 | GO:0038042 | dimeric G-protein coupled receptor signaling pathway(GO:0038042) |
| 0.1 | 1.7 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.1 | 1.2 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.1 | 1.1 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.0 | 0.4 | GO:0035973 | aggrephagy(GO:0035973) |
| 0.0 | 0.3 | GO:2000768 | positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
| 0.0 | 0.8 | GO:0006568 | tryptophan metabolic process(GO:0006568) |
| 0.0 | 0.4 | GO:0015755 | fructose transport(GO:0015755) |
| 0.0 | 3.4 | GO:0008542 | visual learning(GO:0008542) |
| 0.0 | 0.3 | GO:0015853 | adenine transport(GO:0015853) |
| 0.0 | 0.7 | GO:0030853 | negative regulation of granulocyte differentiation(GO:0030853) |
| 0.0 | 2.0 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
| 0.0 | 0.4 | GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
| 0.0 | 0.9 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.0 | 0.5 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.0 | 1.2 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
| 0.0 | 0.2 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 0.0 | 0.6 | GO:1903351 | response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351) |
| 0.0 | 1.0 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.0 | 0.4 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.0 | 0.6 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.0 | 1.3 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.0 | 2.9 | GO:0043486 | histone exchange(GO:0043486) |
| 0.0 | 1.2 | GO:2000785 | regulation of autophagosome assembly(GO:2000785) |
| 0.0 | 1.3 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.0 | 0.4 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 0.0 | 0.1 | GO:0001188 | RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189) |
| 0.0 | 0.1 | GO:0006711 | estrogen catabolic process(GO:0006711) |
| 0.0 | 3.4 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 0.7 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 0.0 | 0.1 | GO:0019417 | sulfur oxidation(GO:0019417) |
| 0.0 | 1.4 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 3.9 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
| 0.0 | 0.1 | GO:0061743 | motor learning(GO:0061743) |
| 0.0 | 0.4 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 0.0 | 1.5 | GO:0090278 | negative regulation of peptide hormone secretion(GO:0090278) |
| 0.0 | 0.2 | GO:0072695 | negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695) |
| 0.0 | 0.7 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.0 | 0.6 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.0 | 3.4 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.6 | GO:2000678 | negative regulation of transcription regulatory region DNA binding(GO:2000678) |
| 0.0 | 1.0 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.0 | 0.7 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
| 0.0 | 1.3 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 0.2 | GO:0097411 | hypoxia-inducible factor-1alpha signaling pathway(GO:0097411) |
| 0.0 | 0.2 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.0 | 0.2 | GO:0031179 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 0.0 | 0.8 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.0 | 0.8 | GO:0034776 | response to histamine(GO:0034776) cellular response to histamine(GO:0071420) |
| 0.0 | 0.3 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.0 | 0.5 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.0 | 0.7 | GO:0010745 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) |
| 0.0 | 0.9 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.0 | 0.3 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.0 | 0.2 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 0.0 | 0.6 | GO:0090331 | negative regulation of platelet aggregation(GO:0090331) |
| 0.0 | 0.5 | GO:0032026 | response to magnesium ion(GO:0032026) |
| 0.0 | 0.2 | GO:0072366 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) |
| 0.0 | 0.1 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 0.0 | 0.2 | GO:0021853 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.0 | 0.0 | GO:0043605 | cellular amide catabolic process(GO:0043605) |
| 0.0 | 0.3 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.0 | 0.1 | GO:0072334 | UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334) |
| 0.0 | 1.3 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.5 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.0 | 0.5 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.4 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.0 | 1.6 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.0 | 1.6 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
| 0.0 | 0.1 | GO:2000543 | positive regulation of gastrulation(GO:2000543) |
| 0.0 | 0.9 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.0 | 0.5 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) |
| 0.0 | 0.5 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.0 | 0.9 | GO:0006111 | regulation of gluconeogenesis(GO:0006111) |
| 0.0 | 2.4 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.0 | 1.2 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.0 | 1.9 | GO:0032088 | negative regulation of NF-kappaB transcription factor activity(GO:0032088) |
| 0.0 | 1.4 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.0 | 0.2 | GO:0070234 | positive regulation of T cell apoptotic process(GO:0070234) |
| 0.0 | 0.3 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.0 | 0.4 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.0 | 0.2 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.0 | 3.2 | GO:0006024 | glycosaminoglycan biosynthetic process(GO:0006024) |
| 0.0 | 1.3 | GO:0035690 | cellular response to drug(GO:0035690) |
| 0.0 | 0.4 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.0 | 0.5 | GO:0031069 | hair follicle morphogenesis(GO:0031069) epidermis morphogenesis(GO:0048730) |
| 0.0 | 0.3 | GO:0097324 | mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748) |
| 0.0 | 0.2 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.0 | 0.1 | GO:1904428 | negative regulation of tubulin deacetylation(GO:1904428) |
| 0.0 | 1.1 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.0 | 0.1 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 0.0 | 0.8 | GO:0010259 | multicellular organism aging(GO:0010259) |
| 0.0 | 1.1 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.3 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
| 0.0 | 0.6 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.0 | 1.4 | GO:0007040 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.0 | 0.2 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.0 | 1.1 | GO:0002011 | morphogenesis of an epithelial sheet(GO:0002011) |
| 0.0 | 0.3 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.0 | 1.8 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.0 | 0.3 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.2 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
| 0.0 | 0.2 | GO:0046885 | regulation of hormone biosynthetic process(GO:0046885) |
| 0.0 | 1.2 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
| 0.0 | 1.1 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.0 | 0.6 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.0 | 0.2 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.0 | 2.0 | GO:0006813 | potassium ion transport(GO:0006813) |
| 0.0 | 0.1 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.0 | 0.1 | GO:2000690 | negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691) |
| 0.0 | 0.8 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.0 | 0.4 | GO:0010832 | negative regulation of myotube differentiation(GO:0010832) |
| 0.0 | 0.3 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.0 | 0.3 | GO:0030166 | proteoglycan biosynthetic process(GO:0030166) |
| 0.0 | 0.5 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.0 | 0.5 | GO:0048665 | neuron fate specification(GO:0048665) |
| 0.0 | 0.2 | GO:0001516 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
| 0.0 | 0.5 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
| 0.0 | 0.2 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.0 | 0.1 | GO:0030497 | fatty acid elongation(GO:0030497) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.2 | 21.0 | GO:0072534 | perineuronal net(GO:0072534) |
| 1.3 | 8.9 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 1.1 | 7.5 | GO:0032280 | symmetric synapse(GO:0032280) |
| 1.0 | 7.9 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.7 | 4.9 | GO:0098843 | postsynaptic endocytic zone(GO:0098843) |
| 0.7 | 2.8 | GO:0038038 | G-protein coupled receptor homodimeric complex(GO:0038038) |
| 0.5 | 3.5 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 0.4 | 11.4 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.4 | 4.6 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.3 | 1.0 | GO:0030312 | external encapsulating structure(GO:0030312) |
| 0.3 | 1.3 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.3 | 6.7 | GO:0042627 | chylomicron(GO:0042627) |
| 0.3 | 2.5 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 0.3 | 0.6 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.3 | 1.9 | GO:0034666 | integrin alpha2-beta1 complex(GO:0034666) |
| 0.3 | 1.8 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554) |
| 0.3 | 1.4 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.3 | 2.1 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.3 | 0.8 | GO:1990742 | microvesicle(GO:1990742) |
| 0.3 | 9.0 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.2 | 5.9 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.2 | 2.7 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.2 | 3.4 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.2 | 0.7 | GO:0036117 | hyaluranon cable(GO:0036117) |
| 0.2 | 1.2 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 0.2 | 0.7 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 0.2 | 1.8 | GO:0033165 | interphotoreceptor matrix(GO:0033165) |
| 0.2 | 2.6 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.2 | 1.3 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.2 | 12.0 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.2 | 5.9 | GO:0031045 | dense core granule(GO:0031045) |
| 0.2 | 2.6 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.2 | 0.8 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 0.2 | 3.3 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.2 | 0.5 | GO:0097444 | spine apparatus(GO:0097444) |
| 0.2 | 7.3 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.2 | 9.6 | GO:0030673 | axolemma(GO:0030673) |
| 0.2 | 1.9 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.2 | 1.5 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.2 | 4.8 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 4.0 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.1 | 2.8 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 25.0 | GO:0043204 | perikaryon(GO:0043204) |
| 0.1 | 0.7 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.1 | 0.7 | GO:0008275 | gamma-tubulin small complex(GO:0008275) |
| 0.1 | 1.8 | GO:0061200 | clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202) |
| 0.1 | 2.8 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 1.5 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.1 | 53.5 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 1.2 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.1 | 0.5 | GO:0071920 | cleavage body(GO:0071920) |
| 0.1 | 2.2 | GO:0097433 | dense body(GO:0097433) |
| 0.1 | 0.9 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.1 | 0.6 | GO:1990498 | mitotic spindle microtubule(GO:1990498) |
| 0.1 | 2.6 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 3.3 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.1 | 0.4 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 0.1 | 1.3 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.1 | 0.8 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.1 | 0.6 | GO:0071942 | XPC complex(GO:0071942) |
| 0.1 | 21.9 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 0.4 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.1 | 0.4 | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956) |
| 0.1 | 2.9 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.1 | 1.7 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.1 | 11.2 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 0.7 | GO:0016012 | dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012) |
| 0.1 | 1.1 | GO:0043218 | compact myelin(GO:0043218) |
| 0.1 | 1.4 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 2.8 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 2.3 | GO:0044306 | neuron projection terminus(GO:0044306) |
| 0.1 | 1.5 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 0.3 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
| 0.1 | 1.1 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.1 | 0.5 | GO:0097648 | G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648) |
| 0.1 | 2.7 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.1 | 0.3 | GO:0090498 | extrinsic component of Golgi membrane(GO:0090498) |
| 0.1 | 1.6 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.1 | 1.6 | GO:0016342 | catenin complex(GO:0016342) |
| 0.1 | 4.9 | GO:0044309 | dendritic spine(GO:0043197) neuron spine(GO:0044309) |
| 0.1 | 19.8 | GO:0030424 | axon(GO:0030424) |
| 0.1 | 0.7 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.1 | 1.9 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.0 | 6.3 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 3.5 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
| 0.0 | 3.6 | GO:0030658 | transport vesicle membrane(GO:0030658) |
| 0.0 | 2.9 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 1.3 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 0.8 | GO:0033643 | host cell part(GO:0033643) |
| 0.0 | 5.9 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.5 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.0 | 0.3 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.0 | 0.2 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.0 | 14.5 | GO:0098793 | presynapse(GO:0098793) |
| 0.0 | 0.5 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 0.8 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.0 | 0.2 | GO:0031417 | NatC complex(GO:0031417) |
| 0.0 | 0.4 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.0 | 0.2 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.0 | 0.4 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 0.0 | 0.9 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 0.4 | GO:0034464 | BBSome(GO:0034464) |
| 0.0 | 5.9 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 2.3 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.3 | GO:0030118 | clathrin coat(GO:0030118) |
| 0.0 | 0.6 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 1.9 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.2 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 0.3 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.0 | 0.2 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.0 | 0.7 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.0 | 3.4 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 3.6 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 3.9 | GO:0030666 | endocytic vesicle membrane(GO:0030666) |
| 0.0 | 0.6 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 0.2 | GO:0090661 | box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 0.0 | 11.3 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 0.5 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.0 | 0.3 | GO:0030478 | actin cap(GO:0030478) |
| 0.0 | 0.2 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.0 | 0.3 | GO:0097486 | multivesicular body lumen(GO:0097486) |
| 0.0 | 0.5 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 1.7 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.1 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.0 | 0.5 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.0 | 5.6 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
| 0.0 | 2.4 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 1.1 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 15.9 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
| 0.0 | 1.0 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.0 | 0.7 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
| 0.0 | 1.3 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 2.2 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.4 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.0 | 1.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.2 | GO:0070187 | telosome(GO:0070187) |
| 0.0 | 0.2 | GO:0000796 | condensin complex(GO:0000796) |
| 0.0 | 8.3 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 2.9 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 0.5 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 0.9 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.1 | GO:0031501 | mannosyltransferase complex(GO:0031501) |
| 0.0 | 0.6 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 4.9 | GO:0043005 | neuron projection(GO:0043005) |
| 0.0 | 0.1 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.0 | 0.6 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 1.3 | GO:0034702 | ion channel complex(GO:0034702) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 7.9 | GO:0032440 | 2-alkenal reductase [NAD(P)] activity(GO:0032440) |
| 1.9 | 5.7 | GO:0060175 | brain-derived neurotrophic factor-activated receptor activity(GO:0060175) |
| 1.8 | 8.8 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
| 1.2 | 10.5 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 1.0 | 4.2 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 1.0 | 5.7 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.9 | 2.7 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 0.8 | 3.1 | GO:0102007 | lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007) |
| 0.7 | 2.9 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 0.7 | 4.3 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
| 0.6 | 3.8 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 0.6 | 2.5 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.6 | 9.7 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.6 | 8.9 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.6 | 5.7 | GO:0042835 | BRE binding(GO:0042835) |
| 0.6 | 1.7 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 0.5 | 10.7 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.5 | 2.1 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.5 | 0.5 | GO:0097603 | temperature-gated ion channel activity(GO:0097603) temperature-gated cation channel activity(GO:0097604) |
| 0.5 | 3.5 | GO:0003867 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
| 0.5 | 4.9 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.5 | 6.4 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.5 | 1.9 | GO:0031751 | D4 dopamine receptor binding(GO:0031751) |
| 0.5 | 1.5 | GO:0047012 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012) |
| 0.5 | 20.8 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.5 | 1.9 | GO:0031687 | A2A adenosine receptor binding(GO:0031687) |
| 0.5 | 0.5 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062) |
| 0.4 | 2.2 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 0.4 | 1.7 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.4 | 1.2 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 0.4 | 2.8 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
| 0.4 | 1.1 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 0.4 | 2.2 | GO:0035473 | lipase binding(GO:0035473) |
| 0.4 | 5.0 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.4 | 1.4 | GO:0005163 | nerve growth factor receptor binding(GO:0005163) |
| 0.4 | 1.4 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
| 0.3 | 2.1 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.3 | 4.4 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.3 | 1.0 | GO:0030305 | heparanase activity(GO:0030305) |
| 0.3 | 9.1 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.3 | 8.6 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.3 | 1.3 | GO:0047888 | fatty acid peroxidase activity(GO:0047888) |
| 0.3 | 1.6 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.3 | 0.9 | GO:0015322 | proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322) |
| 0.3 | 11.9 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.3 | 4.7 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.3 | 1.2 | GO:0050211 | procollagen galactosyltransferase activity(GO:0050211) |
| 0.3 | 1.8 | GO:1902444 | riboflavin binding(GO:1902444) |
| 0.3 | 3.0 | GO:0047035 | testosterone dehydrogenase (NAD+) activity(GO:0047035) |
| 0.3 | 10.9 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.3 | 2.8 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.3 | 1.1 | GO:0032089 | NACHT domain binding(GO:0032089) |
| 0.3 | 2.7 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.3 | 1.8 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.3 | 5.1 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.2 | 14.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.2 | 1.5 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.2 | 1.9 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.2 | 2.4 | GO:0031812 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 0.2 | 1.4 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.2 | 9.0 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.2 | 0.9 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.2 | 1.2 | GO:0033906 | hyaluronoglucuronidase activity(GO:0033906) |
| 0.2 | 1.6 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.2 | 1.1 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.2 | 2.7 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.2 | 2.6 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.2 | 1.3 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.2 | 2.8 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.2 | 1.1 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
| 0.2 | 0.8 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.2 | 1.2 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.2 | 3.1 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.2 | 1.9 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.2 | 2.1 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 0.2 | 6.5 | GO:0022842 | leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842) |
| 0.2 | 2.4 | GO:0043176 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.2 | 1.0 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.2 | 0.8 | GO:0031731 | CCR6 chemokine receptor binding(GO:0031731) |
| 0.2 | 3.3 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.2 | 4.2 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.2 | 3.9 | GO:0008430 | selenium binding(GO:0008430) |
| 0.2 | 10.5 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.2 | 6.1 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.2 | 4.8 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.2 | 1.4 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.2 | 5.9 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.2 | 9.0 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.2 | 1.0 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.2 | 1.3 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.2 | 0.5 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.2 | 13.2 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.2 | 0.8 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 0.2 | 0.3 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
| 0.2 | 0.8 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.1 | 0.7 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.1 | 1.6 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.1 | 3.0 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.1 | 2.0 | GO:0036122 | BMP binding(GO:0036122) |
| 0.1 | 1.9 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 1.4 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
| 0.1 | 1.4 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.1 | 3.4 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 2.6 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.1 | 3.9 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.4 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 0.1 | 0.7 | GO:0048763 | calcium-induced calcium release activity(GO:0048763) |
| 0.1 | 2.6 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 0.5 | GO:0051431 | corticotropin-releasing hormone receptor 2 binding(GO:0051431) |
| 0.1 | 4.4 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 0.5 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 0.1 | 0.5 | GO:0033265 | choline binding(GO:0033265) |
| 0.1 | 0.6 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.1 | 0.5 | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 0.1 | 5.8 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.1 | 12.1 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.1 | 2.8 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.1 | 1.1 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
| 0.1 | 0.4 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
| 0.1 | 2.4 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 0.1 | 2.3 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.1 | 0.8 | GO:0004366 | glycerol-3-phosphate O-acyltransferase activity(GO:0004366) |
| 0.1 | 0.6 | GO:0004329 | formate-tetrahydrofolate ligase activity(GO:0004329) |
| 0.1 | 0.5 | GO:0031716 | calcitonin receptor binding(GO:0031716) |
| 0.1 | 0.3 | GO:0008386 | cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) |
| 0.1 | 0.7 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 0.1 | 1.3 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.1 | 0.8 | GO:0004909 | interleukin-1, Type I, activating receptor activity(GO:0004909) |
| 0.1 | 8.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 1.1 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) |
| 0.1 | 4.5 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 2.2 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
| 0.1 | 2.2 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.1 | 2.1 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.1 | 0.9 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.1 | 1.9 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.1 | 1.0 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.1 | 7.4 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.1 | 1.3 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.1 | 0.3 | GO:0016503 | pheromone receptor activity(GO:0016503) |
| 0.1 | 1.0 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
| 0.1 | 1.8 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.1 | 0.6 | GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509) |
| 0.1 | 0.5 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
| 0.1 | 1.4 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.1 | 0.8 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.1 | 2.2 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 0.5 | GO:0033677 | DNA/RNA helicase activity(GO:0033677) |
| 0.1 | 5.3 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.1 | 6.4 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 1.5 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.1 | 0.4 | GO:0072591 | citrate-L-glutamate ligase activity(GO:0072591) |
| 0.1 | 0.4 | GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567) |
| 0.1 | 0.3 | GO:0033754 | indoleamine 2,3-dioxygenase activity(GO:0033754) |
| 0.1 | 2.0 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.1 | 0.6 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.1 | 0.3 | GO:0032428 | sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428) |
| 0.1 | 0.5 | GO:0017098 | sulfonylurea receptor binding(GO:0017098) |
| 0.1 | 0.5 | GO:0090554 | phosphatidylcholine-translocating ATPase activity(GO:0090554) |
| 0.1 | 0.3 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.1 | 1.9 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 0.2 | GO:0008193 | tRNA guanylyltransferase activity(GO:0008193) |
| 0.1 | 10.2 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.1 | 0.8 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.1 | 1.8 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.1 | 0.4 | GO:0015154 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
| 0.1 | 0.2 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.1 | 3.3 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.1 | 0.2 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
| 0.1 | 1.9 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.7 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 1.9 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.1 | 2.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 5.2 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.1 | 0.4 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.1 | 0.5 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.1 | 0.5 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 0.1 | 0.3 | GO:0008745 | N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) |
| 0.1 | 1.8 | GO:0030553 | cGMP binding(GO:0030553) |
| 0.1 | 0.3 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.1 | 0.6 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.1 | 2.1 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 1.0 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.1 | 0.2 | GO:0030617 | transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) |
| 0.1 | 0.2 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.1 | 0.7 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.1 | 0.6 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.1 | 1.2 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.1 | 0.8 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.1 | 1.7 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.1 | 0.1 | GO:0035276 | ethanol binding(GO:0035276) |
| 0.1 | 0.4 | GO:0015204 | urea transmembrane transporter activity(GO:0015204) |
| 0.1 | 0.9 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.1 | 0.4 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
| 0.1 | 0.2 | GO:0016165 | linoleate 13S-lipoxygenase activity(GO:0016165) |
| 0.1 | 1.1 | GO:0005351 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
| 0.1 | 0.7 | GO:0005372 | water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250) |
| 0.0 | 1.5 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 0.4 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.0 | 0.4 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
| 0.0 | 0.5 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 1.7 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.0 | 0.6 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
| 0.0 | 7.9 | GO:0005319 | lipid transporter activity(GO:0005319) |
| 0.0 | 0.3 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.0 | 0.3 | GO:0015189 | L-lysine transmembrane transporter activity(GO:0015189) |
| 0.0 | 0.6 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 2.5 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.4 | GO:0043426 | MRF binding(GO:0043426) |
| 0.0 | 1.2 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 0.6 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 3.4 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 0.0 | 0.9 | GO:0008391 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.0 | 0.9 | GO:0031404 | chloride ion binding(GO:0031404) |
| 0.0 | 1.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 6.9 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 1.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 1.2 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.3 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 0.0 | 14.9 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.0 | 0.9 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 0.3 | GO:0047288 | monosialoganglioside sialyltransferase activity(GO:0047288) |
| 0.0 | 0.4 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.0 | 0.5 | GO:0016594 | glycine binding(GO:0016594) |
| 0.0 | 0.3 | GO:0015288 | porin activity(GO:0015288) |
| 0.0 | 0.4 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 0.9 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.0 | 0.2 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.0 | 0.2 | GO:0004598 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 0.0 | 5.0 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 2.5 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.0 | 1.7 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 1.2 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 1.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 2.0 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 0.1 | GO:0000702 | oxidized base lesion DNA N-glycosylase activity(GO:0000702) |
| 0.0 | 5.6 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) |
| 0.0 | 3.0 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.2 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 0.8 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.0 | 0.3 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) |
| 0.0 | 0.6 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 0.2 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.0 | 0.5 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 1.2 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 0.1 | GO:0004584 | dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584) |
| 0.0 | 1.3 | GO:0019825 | oxygen binding(GO:0019825) |
| 0.0 | 1.5 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.3 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.0 | 0.2 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.0 | 0.5 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.0 | 1.3 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.3 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.0 | 0.1 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.0 | 0.2 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.0 | 0.9 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.0 | 0.3 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.0 | 0.2 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.0 | 0.3 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.0 | 0.7 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.1 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
| 0.0 | 0.1 | GO:0004052 | arachidonate 12-lipoxygenase activity(GO:0004052) |
| 0.0 | 0.0 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 0.0 | 0.3 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.0 | 0.1 | GO:0005502 | 11-cis retinal binding(GO:0005502) |
| 0.0 | 0.2 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.0 | 0.2 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.0 | 1.0 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 0.2 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.0 | 0.9 | GO:0035254 | glutamate receptor binding(GO:0035254) |
| 0.0 | 0.2 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.0 | 0.3 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.0 | 0.3 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 0.2 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 0.2 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 0.0 | 1.0 | GO:0008375 | acetylglucosaminyltransferase activity(GO:0008375) |
| 0.0 | 0.8 | GO:0005549 | odorant binding(GO:0005549) |
| 0.0 | 0.6 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.1 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.0 | 0.8 | GO:0032947 | protein complex scaffold(GO:0032947) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.7 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.2 | 9.7 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 5.3 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 15.5 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.1 | 2.3 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 5.4 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.1 | 10.7 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 1.9 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.1 | 8.3 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.1 | 6.6 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.1 | 0.7 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.1 | 4.1 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 7.4 | PID FGF PATHWAY | FGF signaling pathway |
| 0.1 | 1.6 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.1 | 25.3 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 5.0 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 2.6 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.1 | 1.3 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 2.5 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 1.2 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 1.2 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 1.8 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.1 | 1.8 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 1.5 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.0 | 3.9 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.2 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 0.5 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.0 | 1.2 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 2.0 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 1.9 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 4.2 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 1.5 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 0.5 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 0.7 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 1.4 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.8 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 0.5 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.5 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.3 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.0 | 0.1 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 0.5 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.0 | 0.5 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.5 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 14.6 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.6 | 11.8 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.4 | 13.0 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.4 | 18.0 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.4 | 6.0 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.3 | 8.7 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.3 | 3.5 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.3 | 14.6 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.3 | 7.1 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.3 | 14.5 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.2 | 13.6 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.2 | 4.8 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.2 | 6.2 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.2 | 1.3 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.2 | 5.1 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.1 | 1.7 | REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) |
| 0.1 | 5.0 | REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
| 0.1 | 1.1 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.1 | 4.5 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 2.0 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.1 | 1.9 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.1 | 1.9 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 4.9 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 3.1 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 9.2 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.1 | 3.2 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 5.8 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 1.8 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.1 | 1.7 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 4.1 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 4.1 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.1 | 2.4 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.1 | 2.0 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.1 | 4.1 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 1.2 | REACTOME DAG AND IP3 SIGNALING | Genes involved in DAG and IP3 signaling |
| 0.1 | 1.7 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.1 | 1.0 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.1 | 1.9 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 1.2 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.1 | 4.9 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 3.0 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.1 | 2.3 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 0.3 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.1 | 6.0 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 0.5 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.1 | 1.4 | REACTOME GLUCAGON TYPE LIGAND RECEPTORS | Genes involved in Glucagon-type ligand receptors |
| 0.1 | 2.8 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.1 | 1.1 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.1 | 1.2 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.1 | 1.0 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 2.1 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.1 | 1.7 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.1 | 2.3 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.1 | 1.4 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 3.2 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 0.8 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 3.1 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.9 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.0 | 3.5 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 1.8 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 3.5 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.0 | 2.6 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 3.0 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 1.6 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 1.4 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.0 | 2.6 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.0 | 1.2 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 1.0 | REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM | Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism |
| 0.0 | 1.0 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 1.5 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.7 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 0.6 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.0 | 1.1 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.6 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.4 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.0 | 1.0 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 0.9 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 0.7 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 3.2 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.4 | REACTOME SIGNALING BY NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.0 | 3.0 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 0.4 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 1.7 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 1.0 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.0 | 0.3 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 1.2 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.7 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.6 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 2.3 | REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE | Genes involved in NGF signalling via TRKA from the plasma membrane |
| 0.0 | 0.2 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 0.4 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 0.4 | REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT | Genes involved in Lipid digestion, mobilization, and transport |
| 0.0 | 0.1 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.0 | 0.6 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 1.0 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.0 | 0.3 | REACTOME AMYLOIDS | Genes involved in Amyloids |