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Illumina Body Map 2 (GSE30611)

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Results for ESR1

Z-value: 2.49

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Transcription factors associated with ESR1

Gene Symbol Gene ID Gene Info
ENSG00000091831.24 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESR1hg38_v1_chr6_+_151809105_1518091390.251.6e-01Click!

Activity profile of ESR1 motif

Sorted Z-values of ESR1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_22686724 19.35 ENST00000390305.2
immunoglobulin lambda variable 3-25
chr22_+_22758698 15.61 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr22_+_22409755 10.19 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr22_+_22792485 9.91 ENST00000390314.2
immunoglobulin lambda variable 2-11
chr22_+_22369601 9.81 ENST00000390295.3
immunoglobulin lambda variable 7-46
chr14_-_105588322 9.54 ENST00000497872.4
ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr22_+_22880706 9.26 ENST00000390319.2
immunoglobulin lambda variable 3-1
chr2_-_88947820 9.11 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr22_+_22380766 9.00 ENST00000390297.3
immunoglobulin lambda variable 1-44
chr2_-_89100352 8.88 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr22_+_22195753 8.80 ENST00000390285.4
immunoglobulin lambda variable 6-57
chr2_-_89010515 7.98 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr22_+_22322452 7.88 ENST00000390290.3
immunoglobulin lambda variable 1-51
chr22_+_22357739 7.87 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr2_-_89213917 7.81 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr2_-_89268506 7.67 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr22_+_22906342 7.27 ENST00000390325.2
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr2_-_89117844 7.06 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr22_+_22395005 6.98 ENST00000390298.2
immunoglobulin lambda variable 7-43
chr2_-_88966767 6.93 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr22_+_22697789 6.50 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr22_+_22895368 6.49 ENST00000390321.2
immunoglobulin lambda constant 1
chr14_-_105708627 6.40 ENST00000641837.1
ENST00000390547.3
immunoglobulin heavy constant alpha 1
chr2_-_88992903 6.29 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr22_+_22822658 6.12 ENST00000620395.2
immunoglobulin lambda variable 2-8
chr22_+_22900976 5.96 ENST00000390323.2
immunoglobulin lambda constant 2
chr2_+_89862438 5.87 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr14_-_106360320 5.78 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr14_-_106269133 5.67 ENST00000390609.3
immunoglobulin heavy variable 3-23
chr14_-_106762576 5.65 ENST00000624687.1
immunoglobulin heavy variable 1-69D
chr22_+_22030934 5.52 ENST00000390282.2
immunoglobulin lambda variable 4-69
chr8_+_11494367 5.28 ENST00000259089.9
ENST00000529894.1
BLK proto-oncogene, Src family tyrosine kinase
chr2_-_88979016 5.21 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr2_+_90154073 5.12 ENST00000611391.1
immunoglobulin kappa variable 1D-13
chr14_-_106579223 5.07 ENST00000390626.2
immunoglobulin heavy variable 5-51
chr22_+_22327298 4.97 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr22_+_22668286 4.93 ENST00000390304.2
immunoglobulin lambda variable 3-27
chr17_-_35880350 4.85 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
C-C motif chemokine ligand 5
chr19_-_7732160 4.75 ENST00000676742.1
ENST00000678118.1
ENST00000328853.10
C-type lectin domain family 4 member G
chr22_+_22343185 4.69 ENST00000427632.2
immunoglobulin lambda variable 9-49
chr17_+_36064265 4.50 ENST00000616054.2
C-C motif chemokine ligand 18
chr14_-_106639589 4.42 ENST00000390630.3
immunoglobulin heavy variable 4-61
chr17_-_3691748 4.31 ENST00000552723.1
purinergic receptor P2X 5
chr14_-_94390667 4.22 ENST00000557492.5
ENST00000355814.8
ENST00000437397.5
ENST00000448921.5
ENST00000393088.8
serpin family A member 1
chr19_-_10334723 4.13 ENST00000592945.1
intercellular adhesion molecule 3
chr2_+_230225718 4.10 ENST00000420434.7
ENST00000392045.8
ENST00000417495.7
ENST00000343805.10
SP140 nuclear body protein
chr15_-_22160868 3.98 ENST00000604066.1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr19_+_49335396 3.97 ENST00000598095.5
ENST00000426897.6
ENST00000323906.9
ENST00000535669.6
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr14_-_94390650 3.97 ENST00000449399.7
ENST00000404814.8
serpin family A member 1
chr15_+_32718476 3.94 ENST00000652365.1
gremlin 1, DAN family BMP antagonist
chr2_+_90038848 3.90 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr14_-_94390614 3.83 ENST00000553327.5
ENST00000556955.5
ENST00000557118.5
ENST00000440909.5
serpin family A member 1
chr1_+_206897435 3.74 ENST00000391929.7
ENST00000294984.7
ENST00000611909.4
ENST00000367093.3
interleukin 24
chr14_-_106005574 3.48 ENST00000390595.3
immunoglobulin heavy variable 1-3
chr22_+_22098683 3.46 ENST00000390283.2
immunoglobulin lambda variable 8-61
chr11_+_67404077 3.35 ENST00000542590.2
ENST00000312390.9
TBC1 domain family member 10C
chr2_-_89297785 3.33 ENST00000465170.1
immunoglobulin kappa variable 1-37 (non-functional)
chr6_-_2903300 3.13 ENST00000380698.5
serpin family B member 9
chr22_+_22904850 3.06 ENST00000390324.2
immunoglobulin lambda joining 3
chr22_-_23754376 3.03 ENST00000398465.3
ENST00000248948.4
V-set pre-B cell surrogate light chain 3
chr16_+_30183595 2.97 ENST00000219150.10
ENST00000570045.5
ENST00000565497.5
ENST00000570244.5
coronin 1A
chr14_+_100019375 2.87 ENST00000544450.6
Enah/Vasp-like
chr9_-_120926752 2.85 ENST00000373887.8
TNF receptor associated factor 1
chr6_-_30686624 2.84 ENST00000274853.8
protein phosphatase 1 regulatory subunit 18
chr19_+_544034 2.82 ENST00000592501.5
ENST00000264553.6
granzyme M
chr2_+_118942188 2.80 ENST00000327097.5
macrophage receptor with collagenous structure
chr3_+_46979659 2.75 ENST00000450053.8
neurobeachin like 2
chr3_+_186930518 2.75 ENST00000169298.8
ENST00000457772.6
ENST00000455441.5
ENST00000427315.5
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr15_+_88639009 2.67 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr3_+_186930759 2.66 ENST00000677292.1
ENST00000458216.5
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr5_-_67196791 2.63 ENST00000256447.5
CD180 molecule
chr19_+_18173804 2.62 ENST00000407280.4
IFI30 lysosomal thiol reductase
chr4_-_154590735 2.61 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
fibrinogen alpha chain
chr11_+_67403887 2.57 ENST00000526387.5
TBC1 domain family member 10C
chr1_+_161707244 2.55 ENST00000349527.8
ENST00000294796.8
ENST00000309691.10
ENST00000367953.7
ENST00000367950.2
Fc receptor like A
chr2_+_230225756 2.54 ENST00000373645.3
SP140 nuclear body protein
chr6_+_37005630 2.51 ENST00000274963.13
FYVE, RhoGEF and PH domain containing 2
chr2_+_89985922 2.47 ENST00000390268.2
immunoglobulin kappa variable 2D-26
chr6_+_35297809 2.44 ENST00000316637.7
DEF6 guanine nucleotide exchange factor
chr19_-_7747511 2.41 ENST00000593660.5
ENST00000204801.12
ENST00000315591.12
ENST00000354397.10
ENST00000394161.9
ENST00000593821.5
ENST00000602261.5
ENST00000601256.1
ENST00000601951.5
ENST00000315599.12
CD209 molecule
chr15_+_81196871 2.40 ENST00000559383.5
ENST00000394660.6
ENST00000683961.1
interleukin 16
chr17_+_50634845 2.38 ENST00000427699.5
ENST00000285238.13
ATP binding cassette subfamily C member 3
chr6_-_73452253 2.35 ENST00000370318.5
ENST00000370315.4
cyclic GMP-AMP synthase
chr3_-_183555696 2.34 ENST00000341319.8
kelch like family member 6
chr12_-_14843517 2.33 ENST00000228936.6
ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)
chr19_-_3606849 2.32 ENST00000375190.10
thromboxane A2 receptor
chr15_+_80933358 2.22 ENST00000560027.1
cell migration inducing hyaluronidase 1
chr6_+_31494881 2.19 ENST00000538442.5
MHC class I polypeptide-related sequence B
chr2_+_218323148 2.19 ENST00000258362.7
PNKD metallo-beta-lactamase domain containing
chr15_+_88638947 2.16 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr19_+_50415799 2.16 ENST00000599632.1
novel protein
chr17_-_31318818 2.09 ENST00000578584.5
novel protein
chr5_+_40679907 2.08 ENST00000302472.4
prostaglandin E receptor 4
chr19_-_4540028 2.07 ENST00000306390.7
leucine rich alpha-2-glycoprotein 1
chr1_-_111427731 2.07 ENST00000369732.4
oviductal glycoprotein 1
chr7_+_2632029 2.05 ENST00000407643.5
tweety family member 3
chr11_+_67289283 2.02 ENST00000511455.7
ankyrin repeat domain 13D
chr15_+_32717994 1.97 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
gremlin 1, DAN family BMP antagonist
chr22_+_22747383 1.96 ENST00000390311.3
immunoglobulin lambda variable 3-16
chr1_+_9651723 1.96 ENST00000377346.9
ENST00000536656.5
ENST00000628140.2
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr1_+_196774813 1.96 ENST00000471440.6
ENST00000391985.7
ENST00000617219.1
ENST00000367425.9
complement factor H related 3
chr5_-_140633167 1.95 ENST00000302014.11
CD14 molecule
chr11_+_47248885 1.94 ENST00000395397.7
ENST00000405576.5
nuclear receptor subfamily 1 group H member 3
chr20_+_63736651 1.93 ENST00000487026.5
ENST00000309546.8
ENST00000480139.5
Lck interacting transmembrane adaptor 1
chr1_+_161707222 1.92 ENST00000236938.12
Fc receptor like A
chr22_+_39456996 1.92 ENST00000341184.7
beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
chr8_-_21913671 1.91 ENST00000523932.1
ENST00000276420.9
docking protein 2
chr2_+_118942290 1.87 ENST00000412481.1
macrophage receptor with collagenous structure
chr3_-_50303565 1.86 ENST00000266031.8
ENST00000395143.6
ENST00000457214.6
ENST00000447605.2
ENST00000395144.7
ENST00000418723.1
hyaluronidase 1
chr1_+_26021768 1.86 ENST00000374280.4
exostosin like glycosyltransferase 1
chr16_-_74700845 1.85 ENST00000308807.12
ENST00000573267.1
mixed lineage kinase domain like pseudokinase
chr19_+_17281863 1.83 ENST00000652132.1
ENST00000404085.7
ENST00000598347.2
ankyrin repeat and LEM domain containing 1
chr1_+_37474572 1.82 ENST00000373087.7
zinc finger CCCH-type containing 12A
chr1_-_206772484 1.82 ENST00000423557.1
interleukin 10
chr14_+_52314280 1.77 ENST00000557436.1
ENST00000245457.6
prostaglandin E receptor 2
chr16_+_1240698 1.76 ENST00000561736.2
ENST00000338844.8
ENST00000461509.6
tryptase alpha/beta 1
chr19_+_7355589 1.76 ENST00000671891.2
Rho/Rac guanine nucleotide exchange factor 18
chr11_+_1870150 1.76 ENST00000429923.5
ENST00000418975.1
ENST00000406638.6
lymphocyte specific protein 1
chr16_+_29459913 1.74 ENST00000360423.12
sulfotransferase family 1A member 4
chr16_-_74700786 1.72 ENST00000306247.11
ENST00000575686.1
mixed lineage kinase domain like pseudokinase
chr19_-_3606577 1.72 ENST00000411851.3
thromboxane A2 receptor
chr6_-_30687200 1.71 ENST00000399199.7
protein phosphatase 1 regulatory subunit 18
chr11_+_1870252 1.69 ENST00000612798.4
lymphocyte specific protein 1
chr15_-_72783685 1.69 ENST00000456471.3
ENST00000311669.12
ADP dependent glucokinase
chr14_-_91253925 1.68 ENST00000531499.2
G protein-coupled receptor 68
chr21_-_44914271 1.68 ENST00000522931.5
integrin subunit beta 2
chr11_+_102317450 1.67 ENST00000615299.4
ENST00000527309.2
ENST00000526421.6
ENST00000263464.9
baculoviral IAP repeat containing 3
chr6_-_73452124 1.67 ENST00000680833.1
cyclic GMP-AMP synthase
chr22_+_22899481 1.66 ENST00000390322.2
immunoglobulin lambda joining 2
chr19_-_7747559 1.65 ENST00000394173.8
CD209 molecule
chr6_-_41039202 1.62 ENST00000244565.8
unc-5 family C-terminal like
chr16_+_726936 1.62 ENST00000549114.5
ENST00000341413.8
ENST00000562187.1
ENST00000564537.5
ENST00000389703.8
hydroxyacylglutathione hydrolase like
chr7_+_99374240 1.61 ENST00000443222.6
ENST00000414376.5
actin related protein 2/3 complex subunit 1B
chr7_+_45574358 1.61 ENST00000297323.12
adenylate cyclase 1
chr3_-_46464868 1.61 ENST00000417439.5
ENST00000231751.9
ENST00000431944.1
lactotransferrin
chr16_-_1230089 1.59 ENST00000612142.1
ENST00000606293.5
tryptase beta 2
chr11_+_47248924 1.58 ENST00000481889.6
ENST00000436778.5
ENST00000531660.5
ENST00000407404.5
nuclear receptor subfamily 1 group H member 3
chr6_-_149484965 1.58 ENST00000409806.8
zinc finger CCCH-type containing 12D
chr16_+_30199255 1.57 ENST00000338971.10
sulfotransferase family 1A member 3
chr9_-_121370275 1.57 ENST00000538954.5
stomatin
chr11_+_65639860 1.57 ENST00000527525.5
signal-induced proliferation-associated 1
chr11_+_102317542 1.56 ENST00000532808.5
baculoviral IAP repeat containing 3
chr11_+_36296281 1.54 ENST00000530639.6
proline rich 5 like
chr8_-_21913661 1.53 ENST00000518197.1
docking protein 2
chr8_-_69833338 1.51 ENST00000524945.5
solute carrier organic anion transporter family member 5A1
chr7_+_99374675 1.51 ENST00000645391.1
ENST00000455009.6
actin related protein 2/3 complex subunit 1B
chr1_+_32362537 1.50 ENST00000373534.4
testis specific serine kinase 3
chr9_+_133534807 1.50 ENST00000393060.1
ADAMTS like 2
chr3_+_122055355 1.49 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chr7_-_1940492 1.47 ENST00000437877.1
mitotic arrest deficient 1 like 1
chr11_+_102317492 1.47 ENST00000673846.1
baculoviral IAP repeat containing 3
chr6_-_90296824 1.47 ENST00000257749.9
BTB domain and CNC homolog 2
chr7_+_2631978 1.46 ENST00000258796.12
tweety family member 3
chr2_-_207166818 1.46 ENST00000423015.5
Kruppel like factor 7
chr22_+_22588155 1.45 ENST00000390302.3
immunoglobulin lambda variable 2-33 (non-functional)
chr9_+_133534697 1.44 ENST00000651351.2
ADAMTS like 2
chr6_+_29827817 1.43 ENST00000360323.11
ENST00000376818.7
ENST00000376815.3
major histocompatibility complex, class I, G
chr9_-_35619542 1.43 ENST00000396757.6
CD72 molecule
chr16_+_30199860 1.43 ENST00000395138.6
sulfotransferase family 1A member 3
chr1_-_19980416 1.41 ENST00000375111.7
phospholipase A2 group IIA
chr19_-_54313074 1.40 ENST00000486742.2
ENST00000432233.8
leukocyte immunoglobulin like receptor A5
chr22_-_50270353 1.40 ENST00000330651.11
mitogen-activated protein kinase 11
chr20_+_62656359 1.39 ENST00000370507.5
solute carrier organic anion transporter family member 4A1
chr8_+_141128581 1.39 ENST00000519811.6
DENN domain containing 3
chr2_-_98731063 1.37 ENST00000393487.6
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
chr21_-_44928711 1.37 ENST00000517563.5
integrin subunit beta 2
chr20_+_38346474 1.36 ENST00000217407.3
lipopolysaccharide binding protein
chr10_+_87659839 1.36 ENST00000456849.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr1_-_156020789 1.35 ENST00000531917.5
ENST00000480567.5
ENST00000526212.2
ENST00000529008.5
ENST00000496742.5
ENST00000295702.9
signal sequence receptor subunit 2
chr7_-_150341615 1.33 ENST00000223271.8
ENST00000466675.5
ENST00000482669.1
ENST00000467793.5
retinoic acid receptor responder 2
chr7_+_142492121 1.32 ENST00000390374.3
T cell receptor beta variable 7-6
chr19_+_45499610 1.30 ENST00000396735.6
protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr6_-_90296908 1.30 ENST00000537989.5
BTB domain and CNC homolog 2
chr8_+_143558329 1.30 ENST00000262580.9
ENST00000525721.1
ENST00000534018.5
gasdermin D
chr5_+_111224374 1.28 ENST00000282356.9
calcium/calmodulin dependent protein kinase IV
chr8_+_141128612 1.27 ENST00000518347.5
ENST00000262585.6
ENST00000520986.5
ENST00000523058.5
ENST00000518668.5
DENN domain containing 3
chr11_+_62419025 1.26 ENST00000278282.3
secretoglobin family 1A member 1
chr11_+_8683201 1.24 ENST00000526562.5
ENST00000525981.1
ribosomal protein L27a
chr6_-_53348902 1.24 ENST00000370913.5
ENST00000304434.11
ELOVL fatty acid elongase 5
chr13_-_46390042 1.23 ENST00000389908.7
rubicon like autophagy enhancer
chr19_-_13102848 1.23 ENST00000264824.5
LYL1 basic helix-loop-helix family member
chr4_+_2798564 1.23 ENST00000504294.5
SH3 domain binding protein 2
chr22_+_37639660 1.22 ENST00000649765.2
ENST00000451997.6
SH3 domain binding protein 1
novel protein
chr19_+_17281645 1.22 ENST00000394458.7
ENST00000594072.6
ankyrin repeat and LEM domain containing 1
chr11_+_8682782 1.21 ENST00000531978.5
ENST00000524496.5
ENST00000532359.5
ENST00000314138.11
ENST00000530022.5
ribosomal protein L27a
chr20_+_33993932 1.21 ENST00000333552.9
RALY heterogeneous nuclear ribonucleoprotein
chr7_-_100573865 1.20 ENST00000622764.3
Sin3A associated protein 25
chr9_+_127716073 1.20 ENST00000373289.4
tetratricopeptide repeat domain 16
chr1_+_12166978 1.19 ENST00000376259.7
ENST00000536782.2
TNF receptor superfamily member 1B
chr19_-_14475307 1.19 ENST00000292513.4
prostaglandin E receptor 1
chr22_+_49918733 1.18 ENST00000407217.7
ENST00000403427.3
cysteine rich with EGF like domains 2
chr17_-_75405486 1.18 ENST00000392562.5
growth factor receptor bound protein 2
chr5_+_111223905 1.18 ENST00000512453.5
calcium/calmodulin dependent protein kinase IV
chr6_+_32154131 1.18 ENST00000375143.6
ENST00000324816.11
ENST00000424499.1
palmitoyl-protein thioesterase 2
chr19_+_47332167 1.17 ENST00000595464.3
complement component 5a receptor 2
chr14_+_21768482 1.17 ENST00000390428.3
T cell receptor alpha variable 6
chr5_-_132011580 1.17 ENST00000651250.1
ENST00000434099.6
ENST00000296869.9
ENST00000651356.1
ENST00000651883.2
acyl-CoA synthetase long chain family member 6
chr3_+_186931344 1.17 ENST00000417392.5
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr15_+_69452811 1.17 ENST00000357790.5
ENST00000260379.11
ENST00000560274.1
ribosomal protein lateral stalk subunit P1
chr5_-_132011811 1.16 ENST00000379255.5
ENST00000430403.5
ENST00000357096.5
acyl-CoA synthetase long chain family member 6

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
1.6 4.9 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
1.6 17.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
1.2 208.7 GO:0006958 complement activation, classical pathway(GO:0006958)
1.2 4.8 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.2 4.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.0 3.1 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
1.0 3.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.0 4.1 GO:0046968 peptide antigen transport(GO:0046968)
0.8 2.4 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.7 3.5 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.7 2.1 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.6 1.8 GO:2000627 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.6 1.8 GO:0060302 negative regulation of interleukin-18 production(GO:0032701) negative regulation of cytokine activity(GO:0060302) negative regulation of chemokine (C-C motif) ligand 5 production(GO:0071650)
0.6 1.8 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.6 3.0 GO:0032796 uropod organization(GO:0032796)
0.6 2.3 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.5 5.9 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.5 2.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.5 0.5 GO:0002458 peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465)
0.5 1.5 GO:0043017 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.5 1.4 GO:0000103 sulfate assimilation(GO:0000103)
0.4 2.6 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.4 1.3 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.4 3.0 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.4 2.9 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.4 1.6 GO:0044010 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.4 2.4 GO:0015722 canalicular bile acid transport(GO:0015722)
0.4 2.8 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.4 1.6 GO:0042631 cellular response to water deprivation(GO:0042631)
0.4 3.0 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.4 1.1 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.3 1.0 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.3 1.0 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.3 2.6 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.3 1.0 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.3 70.9 GO:0002377 immunoglobulin production(GO:0002377)
0.3 2.2 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.3 1.9 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.3 0.9 GO:0006212 uracil catabolic process(GO:0006212) beta-alanine biosynthetic process(GO:0019483)
0.3 1.7 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.3 1.4 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.3 0.8 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.3 7.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.3 0.8 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.3 2.4 GO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.3 1.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.3 0.8 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.3 2.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.3 1.3 GO:0001575 globoside metabolic process(GO:0001575)
0.3 1.3 GO:0010193 response to ozone(GO:0010193)
0.2 0.7 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.2 1.0 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.2 4.7 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.2 1.1 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.2 0.7 GO:1904863 regulation of beta-catenin-TCF complex assembly(GO:1904863) negative regulation of beta-catenin-TCF complex assembly(GO:1904864)
0.2 2.9 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.2 1.3 GO:0019732 antifungal humoral response(GO:0019732) antifungal innate immune response(GO:0061760)
0.2 0.9 GO:0051801 cytolysis in other organism involved in symbiotic interaction(GO:0051801)
0.2 4.8 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.2 2.2 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.2 1.0 GO:0038156 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.2 0.6 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.2 1.0 GO:0071603 retinal blood vessel morphogenesis(GO:0061304) endothelial cell-cell adhesion(GO:0071603)
0.2 2.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 0.6 GO:1904887 regulation of thioredoxin peroxidase activity(GO:1903123) negative regulation of thioredoxin peroxidase activity(GO:1903124) negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation(GO:1903125) Wnt signalosome assembly(GO:1904887) negative regulation of peroxidase activity(GO:2000469)
0.2 2.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.6 GO:0060003 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) copper ion export(GO:0060003)
0.2 0.5 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.2 0.5 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 0.7 GO:0033590 acetaldehyde metabolic process(GO:0006117) response to cobalamin(GO:0033590)
0.2 0.7 GO:0014028 notochord formation(GO:0014028)
0.2 0.7 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.2 1.7 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 1.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.2 1.4 GO:0000012 single strand break repair(GO:0000012)
0.2 1.1 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 0.6 GO:0060734 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496) regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.2 0.5 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 0.9 GO:0001757 somite specification(GO:0001757)
0.1 0.6 GO:0033037 polysaccharide localization(GO:0033037)
0.1 11.5 GO:0006953 acute-phase response(GO:0006953)
0.1 1.3 GO:0071673 positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.1 0.9 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 5.2 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 3.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 3.9 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
0.1 0.7 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 1.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046)
0.1 0.7 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 4.9 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 1.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 5.3 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 0.5 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.1 0.8 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1 0.8 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 0.2 GO:0051885 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of anagen(GO:0051885)
0.1 0.5 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.4 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.9 GO:0072343 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.5 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 1.3 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.3 GO:1903988 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.1 2.1 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.7 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1 1.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 4.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 2.3 GO:0002467 germinal center formation(GO:0002467)
0.1 1.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 0.6 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.1 0.6 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 0.7 GO:0023035 CD40 signaling pathway(GO:0023035)
0.1 1.8 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.6 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.5 GO:0006788 heme oxidation(GO:0006788)
0.1 2.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 1.9 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.1 0.7 GO:0051414 response to cortisol(GO:0051414)
0.1 0.4 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
0.1 4.0 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.4 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 4.8 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 1.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.5 GO:0038203 TORC2 signaling(GO:0038203)
0.1 2.4 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.1 2.7 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.5 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.4 GO:0000050 urea cycle(GO:0000050)
0.1 2.8 GO:0019835 cytolysis(GO:0019835)
0.1 0.3 GO:0070895 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.1 0.3 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 0.4 GO:1900220 negative regulation of alkaline phosphatase activity(GO:0010693) semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.6 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 1.7 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 1.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 1.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 3.0 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.2 GO:0048561 establishment of organ orientation(GO:0048561)
0.1 1.5 GO:0015816 glycine transport(GO:0015816)
0.1 0.7 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 0.6 GO:0070995 NADPH oxidation(GO:0070995)
0.1 1.6 GO:0010226 response to lithium ion(GO:0010226)
0.1 0.4 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 1.0 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 2.3 GO:0006525 arginine metabolic process(GO:0006525)
0.1 0.4 GO:1903232 melanosome assembly(GO:1903232)
0.1 21.8 GO:0002250 adaptive immune response(GO:0002250)
0.1 0.8 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.1 1.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.8 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.1 0.4 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.1 0.5 GO:0061430 bone trabecula morphogenesis(GO:0061430)
0.1 0.5 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.5 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.6 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 2.3 GO:0050779 RNA destabilization(GO:0050779)
0.1 0.8 GO:0060033 anatomical structure regression(GO:0060033)
0.1 0.6 GO:0032682 negative regulation of chemokine production(GO:0032682)
0.1 0.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.2 GO:0021539 subthalamus development(GO:0021539)
0.1 0.3 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 0.7 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 2.1 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.7 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.6 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.3 GO:0015853 adenine transport(GO:0015853)
0.0 1.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.3 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.6 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 3.5 GO:0006968 cellular defense response(GO:0006968)
0.0 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.4 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.7 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 2.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.2 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 1.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 4.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.3 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.4 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.6 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 4.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.9 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.3 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.6 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.2 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 1.4 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 0.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 1.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 2.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.3 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.9 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.4 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 2.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.5 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 2.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.5 GO:0001659 temperature homeostasis(GO:0001659)
0.0 0.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.5 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.0 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
0.0 0.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 1.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.5 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.3 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.0 GO:1903626 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0 0.9 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 1.1 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 0.4 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.5 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0006882 cellular zinc ion homeostasis(GO:0006882)
0.0 0.2 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 15.9 GO:0071752 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752)
1.0 3.1 GO:0036284 tubulobulbar complex(GO:0036284)
0.7 2.1 GO:0030312 external encapsulating structure(GO:0030312)
0.7 35.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.6 1.9 GO:0036117 hyaluranon cable(GO:0036117)
0.4 1.9 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.4 3.0 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.4 1.5 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.3 73.5 GO:0072562 blood microparticle(GO:0072562)
0.3 1.0 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
0.3 1.6 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2 7.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.2 2.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.0 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 1.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 0.6 GO:0099400 cytoplasmic side of mitochondrial outer membrane(GO:0032473) caveola neck(GO:0099400)
0.2 1.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 0.7 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 1.2 GO:0043196 varicosity(GO:0043196)
0.1 1.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.8 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 1.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.8 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 1.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.8 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.4 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 12.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 6.1 GO:0031527 filopodium membrane(GO:0031527)
0.1 1.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 2.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.6 GO:1990031 pinceau fiber(GO:1990031)
0.1 7.4 GO:0001772 immunological synapse(GO:0001772)
0.1 0.9 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.3 GO:0098855 HCN channel complex(GO:0098855)
0.1 1.3 GO:0005605 basal lamina(GO:0005605)
0.1 0.7 GO:0098536 deuterosome(GO:0098536)
0.1 1.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.3 GO:0071817 MMXD complex(GO:0071817)
0.1 0.3 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.4 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 1.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 5.2 GO:0015030 Cajal body(GO:0015030)
0.1 1.5 GO:0031932 TORC2 complex(GO:0031932)
0.1 6.2 GO:0043202 lysosomal lumen(GO:0043202)
0.1 2.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.2 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 5.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.6 GO:0000322 storage vacuole(GO:0000322)
0.0 0.4 GO:0070449 elongin complex(GO:0070449)
0.0 84.1 GO:0005615 extracellular space(GO:0005615)
0.0 2.9 GO:0005581 collagen trimer(GO:0005581)
0.0 8.3 GO:0001650 fibrillar center(GO:0001650)
0.0 4.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 1.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 5.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.4 GO:0030175 filopodium(GO:0030175)
0.0 0.6 GO:0033010 paranodal junction(GO:0033010)
0.0 3.1 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 1.5 GO:0005643 nuclear pore(GO:0005643)
0.0 2.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 3.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.6 GO:0005902 microvillus(GO:0005902)
0.0 1.3 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.7 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 2.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0030897 HOPS complex(GO:0030897)
0.0 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.8 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 1.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 95.1 GO:0005576 extracellular region(GO:0005576)
0.0 4.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0070461 SAGA-type complex(GO:0070461)
0.0 0.5 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.8 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.8 GO:0030666 endocytic vesicle membrane(GO:0030666)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
1.6 4.8 GO:0008859 exoribonuclease II activity(GO:0008859)
1.1 303.7 GO:0003823 antigen binding(GO:0003823)
1.0 4.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.8 2.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.8 2.4 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.8 2.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.7 3.0 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.7 6.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.6 1.8 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.5 3.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.5 2.9 GO:0050436 microfibril binding(GO:0050436)
0.5 6.3 GO:0016015 morphogen activity(GO:0016015)
0.5 1.9 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.4 3.5 GO:0032810 sterol response element binding(GO:0032810)
0.4 4.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.4 1.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.4 3.3 GO:0071723 lipoteichoic acid binding(GO:0070891) lipopeptide binding(GO:0071723)
0.4 4.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.4 1.4 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.3 1.7 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3 3.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.3 2.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.3 0.8 GO:0090422 thiamine pyrophosphate transporter activity(GO:0090422)
0.3 1.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.2 0.7 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 2.9 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 2.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 0.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.2 1.0 GO:0004914 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.2 1.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 1.1 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.2 0.6 GO:0036479 GTP-dependent protein kinase activity(GO:0034211) peroxidase inhibitor activity(GO:0036479)
0.2 0.6 GO:0004008 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.2 0.9 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.2 0.5 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.2 1.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 2.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 0.7 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2 0.7 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.2 1.0 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.2 0.6 GO:0001855 complement component C4b binding(GO:0001855)
0.2 3.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 3.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 1.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.6 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 2.8 GO:0031996 thioesterase binding(GO:0031996)
0.1 3.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 4.7 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 1.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 2.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 1.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 3.9 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.8 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.7 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 1.0 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 7.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 3.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.6 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 1.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 2.1 GO:0004568 chitinase activity(GO:0004568)
0.1 3.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.7 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 3.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 4.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.3 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.3 GO:0097689 iron channel activity(GO:0097689)
0.1 2.3 GO:0005522 profilin binding(GO:0005522)
0.1 0.5 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 3.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.8 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 1.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.0 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.4 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.6 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.7 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.8 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 12.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.6 GO:0004046 aminoacylase activity(GO:0004046)
0.1 1.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.9 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 0.3 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1 0.8 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.8 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.5 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.0 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.4 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 1.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.5 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.8 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.5 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 1.9 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 5.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.7 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.7 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.3 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.9 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 1.0 GO:0043295 glutathione binding(GO:0043295)
0.0 0.6 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 1.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.0 0.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 1.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 1.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 2.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.0 GO:0070330 aromatase activity(GO:0070330)
0.0 0.7 GO:0008430 selenium binding(GO:0008430)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.8 GO:0001848 complement binding(GO:0001848)
0.0 0.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.5 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.6 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 7.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 5.5 GO:0005125 cytokine activity(GO:0005125)
0.0 1.6 GO:0050699 WW domain binding(GO:0050699)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 5.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.9 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 2.0 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.1 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 4.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 4.3 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 1.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.0 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.6 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 3.7 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.8 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 3.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.0 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 2.6 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 9.7 PID CD40 PATHWAY CD40/CD40L signaling
0.1 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 12.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 6.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 2.2 PID IL5 PATHWAY IL5-mediated signaling events
0.1 1.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 4.8 PID IL23 PATHWAY IL23-mediated signaling events
0.1 4.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 3.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 4.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 3.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 5.7 PID BMP PATHWAY BMP receptor signaling
0.1 3.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 0.8 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 4.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 9.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 3.9 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 1.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 5.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.1 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 3.0 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 6.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 6.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.0 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.3 9.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 9.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.3 2.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2 3.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 10.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 3.6 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 3.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 4.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 6.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 1.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 2.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 9.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 4.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 10.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 3.6 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 2.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 4.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.9 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 1.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 5.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 3.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 5.5 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 2.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 2.5 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 1.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 2.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules