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Illumina Body Map 2 (GSE30611)
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Results for ETV3
Z-value: 0.84
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Transcription factors associated with ETV3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ETV3 | hg38_v1_chr1_-_157138388_157138402 | 0.08 | 6.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_+_70892443 Show fit | 2.11 |
ENST00000443425.6
ENST00000560369.5 |
leucine rich repeat containing 49 |
|
| chr15_-_70892412 Show fit | 1.91 |
ENST00000249861.9
|
THAP domain containing 10 |
|
| chr8_+_38176802 Show fit | 1.57 |
ENST00000287322.5
|
BAG cochaperone 4 |
|
| chr3_+_108589667 Show fit | 1.56 |
ENST00000361582.8
ENST00000486815.5 |
DAZ interacting zinc finger protein 3 |
|
| chr15_+_90265634 Show fit | 1.45 |
ENST00000379095.5
|
neugrin, neurite outgrowth associated |
|
| chr10_-_15860450 Show fit | 1.41 |
ENST00000277632.8
|
MINDY lysine 48 deubiquitinase 3 |
|
| chr21_+_17513003 Show fit | 1.40 |
ENST00000284878.12
ENST00000400166.5 |
CXADR Ig-like cell adhesion molecule |
|
| chr5_+_126423176 Show fit | 1.40 |
ENST00000542322.5
ENST00000544396.5 |
GRAM domain containing 2B |
|
| chr2_-_44361555 Show fit | 1.36 |
ENST00000409957.5
|
prolyl endopeptidase like |
|
| chr2_-_44361485 Show fit | 1.32 |
ENST00000438314.1
ENST00000409411.6 ENST00000409936.5 |
prolyl endopeptidase like |
Network of associatons between targets according to the STRING database.
First level regulatory network of ETV3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.1 | GO:0043101 | purine-containing compound salvage(GO:0043101) |
| 0.1 | 4.0 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.3 | 3.3 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 0.0 | 2.5 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) |
| 0.5 | 2.3 | GO:0098904 | regulation of AV node cell action potential(GO:0098904) |
| 0.3 | 2.2 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.0 | 2.2 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.3 | 2.0 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
| 0.0 | 1.9 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 1.7 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 5.1 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 0.0 | 3.7 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.1 | 2.7 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.1 | 2.3 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.2 | 2.2 | GO:0000835 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.1 | 1.7 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 1.7 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.2 | 1.5 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.0 | 1.5 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 1.5 | GO:0005876 | spindle microtubule(GO:0005876) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 5.1 | GO:0003920 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.1 | 4.0 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.1 | 3.3 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.0 | 3.0 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.1 | 2.5 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.2 | 2.3 | GO:0071253 | connexin binding(GO:0071253) |
| 0.1 | 1.8 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.1 | 1.6 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.2 | 1.4 | GO:0070004 | cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004) |
| 0.1 | 1.3 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 1.4 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 1.3 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 1.1 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 0.9 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.8 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 0.7 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.6 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 0.6 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.4 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.1 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 2.5 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 2.5 | REACTOME PROTEIN FOLDING | Genes involved in Protein folding |
| 0.0 | 2.3 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 2.1 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 2.0 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 1.9 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 1.3 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 1.2 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 1.1 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |