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Illumina Body Map 2 (GSE30611)

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Results for FIGLA

Z-value: 1.00

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Transcription factors associated with FIGLA

Gene Symbol Gene ID Gene Info
ENSG00000183733.6 folliculogenesis specific bHLH transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FIGLAhg38_v1_chr2_-_70790643_707906430.163.8e-01Click!

Activity profile of FIGLA motif

Sorted Z-values of FIGLA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_41102209 3.44 ENST00000440582.1
keratin associated protein 4-16
chr12_+_50104000 2.76 ENST00000548814.1
ENST00000301149.8
glycerol-3-phosphate dehydrogenase 1
chr19_+_50432885 2.14 ENST00000357701.6
myosin binding protein C2
chr17_-_41140487 2.12 ENST00000345847.4
keratin associated protein 4-6
chr20_+_31819348 1.72 ENST00000375985.5
myosin light chain kinase 2
chr20_+_31819302 1.70 ENST00000375994.6
myosin light chain kinase 2
chr2_-_151734467 1.70 ENST00000397345.8
ENST00000427231.7
ENST00000409198.5
nebulin
chr17_+_41105332 1.60 ENST00000391415.1
ENST00000617453.1
keratin associated protein 4-9
chr16_+_30372291 1.46 ENST00000568749.5
myosin light chain, phosphorylatable, fast skeletal muscle
chr6_+_18387326 1.41 ENST00000259939.4
ring finger protein 144B
chr6_-_39229465 1.38 ENST00000359534.4
potassium two pore domain channel subfamily K member 5
chr7_-_27156646 1.38 ENST00000242159.5
homeobox A7
chr6_-_31729260 1.37 ENST00000375789.7
dimethylarginine dimethylaminohydrolase 2
chr2_-_157628727 1.36 ENST00000335450.7
ENST00000348328.9
activin A receptor type 1C
chr11_+_111918900 1.29 ENST00000278601.6
chromosome 11 open reading frame 52
chr2_-_75560893 1.29 ENST00000410113.5
ENST00000393913.8
eva-1 homolog A, regulator of programmed cell death
chr6_-_100464912 1.28 ENST00000369208.8
SIM bHLH transcription factor 1
chr17_+_50056095 1.26 ENST00000320031.13
integrin subunit alpha 3
chr17_-_41168219 1.26 ENST00000391356.4
keratin associated protein 4-3
chr6_+_44216914 1.23 ENST00000573382.3
ENST00000576476.1
myomixer, myoblast fusion factor
chr14_+_75279637 1.23 ENST00000555686.1
ENST00000555672.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr6_-_31729478 1.21 ENST00000436437.2
dimethylarginine dimethylaminohydrolase 2
chr17_+_75525682 1.20 ENST00000392550.8
ENST00000167462.9
ENST00000375227.8
ENST00000578363.5
ENST00000579392.5
LLGL scribble cell polarity complex component 2
chr16_-_11281322 1.18 ENST00000312511.4
protamine 1
chr1_-_114695533 1.16 ENST00000520113.7
adenosine monophosphate deaminase 1
chr6_-_31728877 1.14 ENST00000437288.5
dimethylarginine dimethylaminohydrolase 2
chr2_-_157628852 1.12 ENST00000243349.13
activin A receptor type 1C
chr1_-_114695613 1.12 ENST00000369538.4
adenosine monophosphate deaminase 1
chr7_-_149028651 1.12 ENST00000286091.9
protein disulfide isomerase family A member 4
chr14_+_75280078 1.07 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr7_-_149028452 1.06 ENST00000413966.1
ENST00000652332.1
protein disulfide isomerase family A member 4
chr22_-_50532077 1.02 ENST00000428989.3
ENST00000403326.5
outer dense fiber of sperm tails 3B
chr11_-_117828068 1.00 ENST00000532119.5
ENST00000260287.2
FXYD domain containing ion transport regulator 2
chr6_-_31582415 1.00 ENST00000429299.3
ENST00000446745.2
lymphotoxin beta
chr2_-_164841812 0.99 ENST00000652658.2
ENST00000444537.5
ENST00000414843.5
cordon-bleu WH2 repeat protein like 1
chr9_-_22009272 0.99 ENST00000380142.5
ENST00000276925.7
cyclin dependent kinase inhibitor 2B
chr1_-_54887161 0.99 ENST00000535035.6
ENST00000371269.9
ENST00000436604.2
24-dehydrocholesterol reductase
chr15_+_90872162 0.98 ENST00000680053.1
furin, paired basic amino acid cleaving enzyme
chr3_-_52826834 0.97 ENST00000441637.2
inter-alpha-trypsin inhibitor heavy chain 4
chrX_+_13569593 0.97 ENST00000361306.6
ENST00000380602.3
EGF like domain multiple 6
chr3_-_49685090 0.97 ENST00000448220.5
macrophage stimulating 1
chr22_-_50532137 0.96 ENST00000405135.5
ENST00000401779.5
ENST00000682240.1
outer dense fiber of sperm tails 3B
chr7_+_129144691 0.95 ENST00000486685.3
tetraspanin 33
chr19_+_35248728 0.95 ENST00000602003.1
ENST00000360798.7
ENST00000354900.7
lipolysis stimulated lipoprotein receptor
chr17_-_7262343 0.95 ENST00000571881.2
ENST00000360325.11
claudin 7
chr11_-_118252279 0.94 ENST00000525386.5
ENST00000527472.1
ENST00000278949.9
myelin protein zero like 3
chr12_+_32502114 0.93 ENST00000682739.1
ENST00000427716.7
ENST00000583694.2
FYVE, RhoGEF and PH domain containing 4
chr4_-_151015713 0.93 ENST00000357115.9
LPS responsive beige-like anchor protein
chr17_-_41118369 0.93 ENST00000391413.4
keratin associated protein 4-11
chr22_-_37486357 0.92 ENST00000356998.8
ENST00000416983.7
ENST00000424765.2
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr8_-_48921419 0.91 ENST00000020945.4
snail family transcriptional repressor 2
chr8_-_48921735 0.90 ENST00000396822.6
snail family transcriptional repressor 2
chr12_+_6310669 0.90 ENST00000684764.1
pleckstrin homology and RhoGEF domain containing G6
chr11_+_118304721 0.90 ENST00000361763.9
CD3e molecule
chr11_+_47257604 0.87 ENST00000444396.5
ENST00000457932.5
nuclear receptor subfamily 1 group H member 3
chr19_+_35248375 0.87 ENST00000602122.5
lipolysis stimulated lipoprotein receptor
chr12_+_6310712 0.87 ENST00000536531.5
pleckstrin homology and RhoGEF domain containing G6
chr8_+_22578249 0.85 ENST00000456545.5
PDZ and LIM domain 2
chr5_-_54985579 0.85 ENST00000381405.5
ENST00000381403.4
endothelial cell specific molecule 1
chr19_-_15479469 0.85 ENST00000292609.8
ENST00000340880.5
peptidoglycan recognition protein 2
chr1_-_150697128 0.85 ENST00000427665.1
ENST00000271732.8
golgi phosphoprotein 3 like
chr15_+_90868580 0.85 ENST00000268171.8
furin, paired basic amino acid cleaving enzyme
chr3_+_52420955 0.85 ENST00000465863.1
PHD finger protein 7
chr11_+_118304881 0.85 ENST00000528600.1
CD3e molecule
chr10_+_24208774 0.84 ENST00000376456.8
ENST00000458595.5
ENST00000376452.7
ENST00000430453.6
KIAA1217
chr1_+_183186238 0.84 ENST00000493293.5
ENST00000264144.5
laminin subunit gamma 2
chr1_-_161021096 0.84 ENST00000537746.1
ENST00000368026.11
F11 receptor
chr6_-_31729785 0.83 ENST00000416410.6
dimethylarginine dimethylaminohydrolase 2
chr3_-_49029378 0.83 ENST00000442157.2
ENST00000326739.9
ENST00000677010.1
ENST00000678724.1
ENST00000429182.6
inosine monophosphate dehydrogenase 2
chr1_-_183653307 0.81 ENST00000308641.6
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr10_+_24209129 0.80 ENST00000376454.8
ENST00000635504.1
KIAA1217
chr2_+_46297397 0.79 ENST00000263734.5
endothelial PAS domain protein 1
chrX_+_129738942 0.78 ENST00000371106.4
X-prolyl aminopeptidase 2
chr3_-_50345665 0.78 ENST00000442887.1
ENST00000231749.8
ENST00000360165.7
zinc finger MYND-type containing 10
chr19_+_35248656 0.77 ENST00000621372.4
lipolysis stimulated lipoprotein receptor
chr11_+_68312542 0.77 ENST00000294304.12
LDL receptor related protein 5
chr10_+_8045345 0.77 ENST00000643001.1
GATA binding protein 3
chr19_+_35248694 0.77 ENST00000361790.7
lipolysis stimulated lipoprotein receptor
chr17_-_73092657 0.76 ENST00000580557.5
ENST00000579732.5
ENST00000578620.1
ENST00000542342.6
ENST00000255559.7
ENST00000579018.5
solute carrier family 39 member 11
chr16_-_57479745 0.76 ENST00000566936.5
ENST00000568617.5
ENST00000567276.5
ENST00000569548.5
ENST00000569250.5
ENST00000564378.5
docking protein 4
chr6_-_132734692 0.74 ENST00000509351.5
ENST00000417437.6
ENST00000423615.6
ENST00000427187.6
ENST00000414302.7
ENST00000367927.9
ENST00000450865.2
vanin 3
chr11_-_86955385 0.73 ENST00000531380.2
frizzled class receptor 4
chr20_-_22585451 0.71 ENST00000377115.4
forkhead box A2
chr11_+_60455839 0.70 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
membrane spanning 4-domains A1
chr13_+_48976597 0.70 ENST00000541916.5
fibronectin type III domain containing 3A
chr14_+_75279961 0.69 ENST00000557139.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr17_-_41098084 0.69 ENST00000318329.6
ENST00000333822.5
keratin associated protein 4-8
chr2_-_164841410 0.69 ENST00000342193.8
ENST00000375458.6
cordon-bleu WH2 repeat protein like 1
chr11_-_124762283 0.69 ENST00000444566.5
ENST00000278927.10
ENST00000435477.1
endothelial cell adhesion molecule
chrX_-_11427725 0.68 ENST00000380736.5
Rho GTPase activating protein 6
chr13_-_20192928 0.68 ENST00000382848.5
gap junction protein beta 2
chr10_+_24466487 0.68 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr11_-_33892010 0.67 ENST00000257818.3
LIM domain only 2
chr5_+_69492767 0.66 ENST00000681041.1
ENST00000680098.1
ENST00000680784.1
ENST00000396442.7
ENST00000681895.1
occludin
chr3_+_32238667 0.66 ENST00000458535.6
ENST00000307526.4
CKLF like MARVEL transmembrane domain containing 8
chr19_+_16076485 0.66 ENST00000643579.2
ENST00000646575.1
tropomyosin 4
chr7_-_93226449 0.66 ENST00000394468.7
ENST00000453812.2
HEPACAM family member 2
chr12_-_52834307 0.66 ENST00000330553.6
keratin 79
chr19_+_35248879 0.65 ENST00000347609.8
lipolysis stimulated lipoprotein receptor
chr7_-_11832190 0.65 ENST00000423059.9
ENST00000617773.1
thrombospondin type 1 domain containing 7A
chr12_+_32502178 0.65 ENST00000546442.5
ENST00000683182.1
FYVE, RhoGEF and PH domain containing 4
chr11_-_88337722 0.65 ENST00000677976.1
ENST00000528020.2
ENST00000393301.5
ENST00000529974.2
ENST00000227266.10
ENST00000678464.1
ENST00000679199.1
ENST00000527018.6
ENST00000679224.1
ENST00000678506.1
ENST00000678915.1
ENST00000524463.6
cathepsin C
chr17_-_47957824 0.63 ENST00000300557.3
proline rich 15 like
chr15_-_74873310 0.62 ENST00000562363.5
ENST00000564529.1
ENST00000268099.13
secretory carrier membrane protein 2
chr2_+_232526153 0.62 ENST00000449596.5
ENST00000258385.8
ENST00000543200.5
cholinergic receptor nicotinic delta subunit
chr4_+_105895458 0.62 ENST00000379987.7
nephronectin
chr10_+_23694707 0.62 ENST00000376462.5
KIAA1217
chr19_-_45768627 0.62 ENST00000560160.1
SIX homeobox 5
chr17_+_78168565 0.61 ENST00000225777.8
ENST00000585591.5
ENST00000589711.1
ENST00000588282.5
ENST00000589168.1
synaptogyrin 2
chr3_+_184249621 0.61 ENST00000324557.9
ENST00000402825.7
EEF1A lysine methyltransferase 4
EEF1AKMT4-ECE2 readthrough
chr11_-_119101814 0.60 ENST00000682791.1
ENST00000639704.1
ENST00000354202.9
dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
chr5_-_151087131 0.60 ENST00000315050.11
ENST00000523338.5
ENST00000522100.5
TNFAIP3 interacting protein 1
chr4_+_105895435 0.60 ENST00000453617.6
ENST00000427316.6
ENST00000514622.5
ENST00000305572.12
nephronectin
chr4_-_176195563 0.59 ENST00000280191.7
spermatogenesis associated 4
chr19_+_35449584 0.59 ENST00000246549.2
free fatty acid receptor 2
chr4_+_105895487 0.59 ENST00000506666.5
ENST00000503451.5
nephronectin
chr6_-_42142604 0.57 ENST00000356542.5
ENST00000341865.9
chromosome 6 open reading frame 132
chr1_-_150876571 0.57 ENST00000354396.6
ENST00000358595.10
ENST00000505755.5
aryl hydrocarbon receptor nuclear translocator
chr18_+_31498168 0.57 ENST00000261590.13
ENST00000585206.1
ENST00000683654.1
desmoglein 2
chr1_-_12616762 0.57 ENST00000464917.5
dehydrogenase/reductase 3
chr2_-_223837553 0.56 ENST00000396654.7
ENST00000396653.2
ENST00000443700.5
adaptor related protein complex 1 subunit sigma 3
chr18_-_55322334 0.56 ENST00000630720.3
transcription factor 4
chr14_-_54902807 0.56 ENST00000543643.6
ENST00000536224.2
ENST00000395514.5
ENST00000491895.7
GTP cyclohydrolase 1
chr1_-_17439657 0.56 ENST00000375436.9
regulator of chromosome condensation 2
chrX_-_154014246 0.56 ENST00000444254.1
interleukin 1 receptor associated kinase 1
chr3_+_191329020 0.56 ENST00000392456.4
coiled-coil domain containing 50
chr6_-_24719146 0.56 ENST00000378119.9
chromosome 6 open reading frame 62
chr22_-_50532489 0.56 ENST00000329363.9
ENST00000437588.2
outer dense fiber of sperm tails 3B
chr1_-_16978276 0.55 ENST00000375534.7
microfibril associated protein 2
chr22_+_49918626 0.54 ENST00000328268.9
ENST00000404488.7
cysteine rich with EGF like domains 2
chr5_-_151087660 0.53 ENST00000522226.5
TNFAIP3 interacting protein 1
chr6_-_37258110 0.53 ENST00000357219.4
ENST00000652386.1
ENST00000652639.1
transmembrane protein 217
chr7_+_2647703 0.53 ENST00000403167.5
tweety family member 3
chr3_-_184249520 0.53 ENST00000455059.5
ENST00000445626.6
ALG3 alpha-1,3- mannosyltransferase
chr6_+_135181361 0.52 ENST00000527615.5
ENST00000420123.6
ENST00000525369.5
ENST00000528774.5
ENST00000533624.5
ENST00000534044.5
ENST00000534121.5
MYB proto-oncogene, transcription factor
chr1_-_112707056 0.52 ENST00000369633.6
ENST00000425265.6
ENST00000369632.6
ENST00000436685.6
ENST00000484054.3
ENST00000369636.6
ENST00000369637.5
ENST00000339083.12
ENST00000285735.6
ENST00000369638.6
ras homolog family member C
chr15_+_88638947 0.51 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr5_-_16936231 0.51 ENST00000507288.1
ENST00000274203.13
ENST00000513610.6
myosin X
chr16_+_2026834 0.51 ENST00000424542.7
ENST00000432365.6
SLC9A3 regulator 2
chr1_-_112707314 0.51 ENST00000369642.7
ras homolog family member C
chr1_+_81699665 0.50 ENST00000359929.7
adhesion G protein-coupled receptor L2
chr11_+_66011994 0.50 ENST00000312134.3
cystatin E/M
chr19_+_6464229 0.49 ENST00000600229.6
ENST00000356762.7
crumbs cell polarity complex component 3
chr15_+_88639009 0.49 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr17_+_29568591 0.48 ENST00000581411.6
ENST00000301057.8
tumor protein p53 inducible protein 13
chr11_-_44950151 0.48 ENST00000533940.5
ENST00000533937.1
tumor protein p53 inducible protein 11
chr7_+_130380339 0.48 ENST00000481342.5
ENST00000604896.5
ENST00000011292.8
carboxypeptidase A1
chr3_-_49813880 0.48 ENST00000333486.4
ubiquitin like modifier activating enzyme 7
chr17_+_78169127 0.47 ENST00000590201.1
synaptogyrin 2
chr1_-_153608136 0.47 ENST00000368703.6
S100 calcium binding protein A16
chr22_+_49960760 0.46 ENST00000360612.5
Pim-3 proto-oncogene, serine/threonine kinase
chr12_-_13095628 0.46 ENST00000457134.6
ENST00000537302.5
germ cell associated 1
chr8_+_144358557 0.46 ENST00000530047.5
ENST00000527078.6
ENST00000674870.1
ENST00000526338.7
ENST00000402965.5
ENST00000329994.7
ENST00000526752.3
ENST00000533662.2
ENST00000534725.6
ENST00000674929.1
ENST00000675597.1
ENST00000643944.2
ENST00000675121.1
solute carrier family 52 member 2
chr9_+_87497852 0.46 ENST00000408954.8
death associated protein kinase 1
chr2_-_43595963 0.45 ENST00000405006.8
THADA armadillo repeat containing
chr2_-_27890348 0.45 ENST00000302188.8
ribokinase
chr2_-_174764407 0.45 ENST00000409219.5
ENST00000409542.5
cholinergic receptor nicotinic alpha 1 subunit
chr16_+_4556335 0.44 ENST00000444310.5
chromosome 16 open reading frame 96
chr12_+_68808143 0.44 ENST00000258149.11
ENST00000428863.6
ENST00000393412.7
MDM2 proto-oncogene
chr12_+_121712740 0.44 ENST00000449592.7
transmembrane protein 120B
chr1_-_53142577 0.43 ENST00000620347.5
ENST00000611397.5
solute carrier family 1 member 7
chr7_+_120273129 0.43 ENST00000331113.9
potassium voltage-gated channel subfamily D member 2
chr5_+_157671525 0.43 ENST00000409999.4
chromosome 5 open reading frame 52
chr3_-_167474026 0.43 ENST00000466903.1
ENST00000264677.8
serpin family I member 2
chr1_+_103750406 0.43 ENST00000370079.3
amylase alpha 1C
chr1_-_41918858 0.43 ENST00000372583.6
HIVEP zinc finger 3
chr17_-_48185179 0.42 ENST00000579336.1
src kinase associated phosphoprotein 1
chr19_+_35758143 0.42 ENST00000444637.6
ENST00000396908.8
ENST00000301165.9
proline and serine rich 3
chr19_+_13906255 0.42 ENST00000589606.5
coiled-coil and C2 domain containing 1A
chr1_+_22001654 0.41 ENST00000290122.8
chymotrypsin like elastase 3A
chr13_-_27620520 0.41 ENST00000316334.5
ligand of numb-protein X 2
chr19_-_18522051 0.41 ENST00000262809.9
elongation factor for RNA polymerase II
chr21_-_34888683 0.41 ENST00000344691.8
ENST00000358356.9
RUNX family transcription factor 1
chr4_-_40514543 0.41 ENST00000513473.5
RNA binding motif protein 47
chr19_-_45768843 0.41 ENST00000560168.1
SIX homeobox 5
chr2_-_174764436 0.40 ENST00000409323.1
ENST00000261007.9
ENST00000348749.9
ENST00000672640.1
cholinergic receptor nicotinic alpha 1 subunit
chr17_-_36534790 0.40 ENST00000616207.4
ENST00000616159.4
ENST00000613551.4
myosin XIX
chr14_+_22271921 0.40 ENST00000390464.2
T cell receptor alpha variable 38-1
chr14_-_89619118 0.40 ENST00000345097.8
ENST00000555855.5
ENST00000555353.5
forkhead box N3
chr17_-_36534208 0.40 ENST00000622055.4
myosin XIX
chr1_+_209768597 0.40 ENST00000487271.5
ENST00000477431.1
TRAF3 interacting protein 3
chr5_+_32712257 0.40 ENST00000507141.1
natriuretic peptide receptor 3
chr1_-_171652675 0.40 ENST00000037502.11
myocilin
chr16_+_77191173 0.39 ENST00000248248.8
ENST00000439557.6
ENST00000545553.1
MON1 homolog B, secretory trafficking associated
chr22_-_18518161 0.39 ENST00000619998.1
gamma-glutamyltransferase light chain family member 3
chr20_+_45812632 0.39 ENST00000335046.7
ENST00000356455.9
ENST00000243893.10
ubiquitin conjugating enzyme E2 C
chr2_-_43595980 0.39 ENST00000403856.1
ENST00000404790.5
ENST00000405975.7
THADA armadillo repeat containing
chr12_-_13095798 0.39 ENST00000396302.7
germ cell associated 1
chr11_-_62984690 0.39 ENST00000421062.2
ENST00000458333.6
solute carrier family 22 member 6
chr16_-_11915991 0.38 ENST00000420576.6
G1 to S phase transition 1
chr17_-_7251286 0.38 ENST00000576613.5
CTD nuclear envelope phosphatase 1
chr6_+_41546566 0.38 ENST00000409208.5
ENST00000373057.7
forkhead box P4
chr11_+_71453189 0.37 ENST00000319023.7
NAD synthetase 1
chr6_+_41921491 0.37 ENST00000230340.9
bystin like
chr1_+_209768482 0.37 ENST00000367023.5
TRAF3 interacting protein 3
chr3_+_191329342 0.37 ENST00000392455.9
coiled-coil domain containing 50
chr20_+_45812665 0.37 ENST00000352551.9
ubiquitin conjugating enzyme E2 C
chr8_-_98825628 0.37 ENST00000617590.1
ENST00000518165.5
ENST00000419617.7
serine/threonine kinase 3
chr7_+_100867379 0.37 ENST00000200457.9
ENST00000619988.4
thyroid hormone receptor interactor 6
chr17_-_36534841 0.37 ENST00000614623.5
ENST00000621344.4
myosin XIX

Network of associatons between targets according to the STRING database.

First level regulatory network of FIGLA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:1901383 negative regulation of chorionic trophoblast cell proliferation(GO:1901383)
0.6 1.8 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.6 4.0 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.6 1.7 GO:0007525 somatic muscle development(GO:0007525)
0.5 3.4 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.5 1.8 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.4 2.4 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.4 1.1 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.4 1.8 GO:0097195 pilomotor reflex(GO:0097195)
0.3 1.7 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.3 1.5 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.3 3.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.3 0.9 GO:0032824 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.3 1.1 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3 1.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 0.7 GO:0019085 early viral transcription(GO:0019085)
0.2 0.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 0.8 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.2 2.3 GO:0032264 IMP salvage(GO:0032264)
0.2 1.0 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 4.6 GO:0006527 citrulline metabolic process(GO:0000052) arginine catabolic process(GO:0006527)
0.2 0.6 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.2 0.8 GO:2000703 regulation of cell proliferation involved in mesonephros development(GO:2000606) negative regulation of cell proliferation involved in mesonephros development(GO:2000607) fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000699) glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000701) regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000702) negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000703) regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000733) negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000734)
0.2 0.6 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.2 0.7 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2 0.9 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 1.0 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.2 1.0 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.2 1.5 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.4 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.6 GO:0003165 Purkinje myocyte development(GO:0003165)
0.1 0.9 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.8 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.4 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.1 0.7 GO:0001575 globoside metabolic process(GO:0001575)
0.1 0.7 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 0.4 GO:0035732 nitric oxide storage(GO:0035732)
0.1 0.2 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.1 0.3 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.1 0.7 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.1 0.3 GO:1990697 protein depalmitoleylation(GO:1990697)
0.1 0.4 GO:0036369 transcription factor catabolic process(GO:0036369)
0.1 1.4 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.6 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.4 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.1 0.9 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 0.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.3 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.7 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.6 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 1.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.3 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.5 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.2 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.1 0.4 GO:0019087 transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295)
0.1 0.9 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.3 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 1.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.2 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 1.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.8 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 2.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.8 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.5 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 0.7 GO:0070673 response to interleukin-18(GO:0070673)
0.1 0.4 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 1.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.4 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 1.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.3 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.9 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.5 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.7 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.3 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.7 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 1.4 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0097698 telomere maintenance via base-excision repair(GO:0097698)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.8 GO:0036158 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.0 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0006154 adenosine catabolic process(GO:0006154) hypoxanthine salvage(GO:0043103) inosine biosynthetic process(GO:0046103)
0.0 0.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.8 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.5 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.0 0.9 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 1.2 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.1 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 5.9 GO:0031424 keratinization(GO:0031424)
0.0 0.6 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.7 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 1.0 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.4 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.3 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.0 0.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.4 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 1.2 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 1.2 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 2.1 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.7 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.0 0.4 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 1.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.6 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.3 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 2.5 GO:0048706 embryonic skeletal system development(GO:0048706)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0048179 activin receptor complex(GO:0048179)
0.4 3.2 GO:0035976 AP1 complex(GO:0035976)
0.3 2.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 4.0 GO:0061689 tricellular tight junction(GO:0061689)
0.3 1.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 1.3 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.2 0.9 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.2 0.6 GO:0018444 translation release factor complex(GO:0018444)
0.2 0.8 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 1.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 10.6 GO:0045095 keratin filament(GO:0045095)
0.1 0.3 GO:0036117 hyaluranon cable(GO:0036117)
0.1 1.8 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.4 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 0.4 GO:0035363 histone locus body(GO:0035363)
0.1 0.8 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.2 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 2.1 GO:0032982 myosin filament(GO:0032982)
0.1 0.8 GO:0043256 laminin complex(GO:0043256)
0.1 0.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 1.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 1.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 1.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 2.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.6 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 2.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0038100 nodal binding(GO:0038100)
0.6 4.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.4 2.4 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.4 3.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 1.0 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 0.9 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.3 0.8 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.2 2.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 0.9 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.2 0.7 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 0.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.5 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.6 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.4 GO:0035730 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
0.1 0.3 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.1 0.3 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 0.9 GO:0032810 sterol response element binding(GO:0032810)
0.1 1.7 GO:0042608 T cell receptor binding(GO:0042608)
0.1 1.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.5 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.6 GO:0050436 microfibril binding(GO:0050436)
0.1 0.3 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.7 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.8 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.6 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.4 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 1.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.6 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 1.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.2 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.1 0.8 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.4 GO:0032027 myosin light chain binding(GO:0032027)
0.0 1.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 4.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0008241 tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711)
0.0 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.7 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 1.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 1.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.0 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 2.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.0 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.6 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.0 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0015180 hydrogen:amino acid symporter activity(GO:0005280) L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 2.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 2.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 3.0 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.8 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 2.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.4 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 4.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 3.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 2.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 2.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins