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Illumina Body Map 2 (GSE30611)

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Results for FLI1

Z-value: 1.51

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Transcription factors associated with FLI1

Gene Symbol Gene ID Gene Info
FLI1
ENSG00000151702.17 Fli-1 proto-oncogene, ETS transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FLI1hg38_v1_chr11_+_128694052_1286941080.759.6e-07Click!

Activity profile of FLI1 motif

Sorted Z-values of FLI1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_22822658 7.42 ENST00000620395.2
IGLV2-8
immunoglobulin lambda variable 2-8
chr1_-_153545793 4.59 ENST00000354332.8
ENST00000368716.9
S100A4
S100 calcium binding protein A4
chr22_+_22697789 4.16 ENST00000390306.2
IGLV2-23
immunoglobulin lambda variable 2-23
chr1_+_32251239 4.16 ENST00000373564.7
ENST00000482949.5
ENST00000336890.10
ENST00000495610.6
LCK
LCK proto-oncogene, Src family tyrosine kinase
chr3_+_108822778 4.01 ENST00000295756.11
TRAT1
T cell receptor associated transmembrane adaptor 1
chr1_-_161069666 3.92 ENST00000368016.7
ARHGAP30
Rho GTPase activating protein 30
chr19_+_41877267 3.90 ENST00000221972.8
ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule
chr3_-_183555696 3.86 ENST00000341319.8
KLHL6
kelch like family member 6
chr11_+_60455839 3.81 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
MS4A1
membrane spanning 4-domains A1
chr14_-_106422175 3.67 ENST00000390619.2
IGHV4-39
immunoglobulin heavy variable 4-39
chr10_-_79560386 3.62 ENST00000372327.9
ENST00000417041.1
ENST00000640627.1
ENST00000372325.7
SFTPA2
surfactant protein A2
chr3_+_108822759 3.62 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr14_-_106627685 3.56 ENST00000390629.3
IGHV4-59
immunoglobulin heavy variable 4-59
chr10_-_70602759 3.55 ENST00000373209.2
PRF1
perforin 1
chr6_-_31582415 3.53 ENST00000429299.3
ENST00000446745.2
LTB
lymphotoxin beta
chr10_-_70602731 3.49 ENST00000441259.2
PRF1
perforin 1
chr19_+_49335396 3.44 ENST00000598095.5
ENST00000426897.6
ENST00000323906.9
ENST00000535669.6
ENST00000597602.1
ENST00000595660.1
CD37
CD37 molecule
chr14_-_105940235 3.40 ENST00000390593.2
IGHV6-1
immunoglobulin heavy variable 6-1
chr14_-_106639589 3.37 ENST00000390630.3
IGHV4-61
immunoglobulin heavy variable 4-61
chr11_+_118304881 3.36 ENST00000528600.1
CD3E
CD3e molecule
chr6_+_31586124 3.32 ENST00000418507.6
ENST00000376096.5
ENST00000376099.5
ENST00000376110.7
LST1
leukocyte specific transcript 1
chr14_-_106374129 3.32 ENST00000390616.2
IGHV4-34
immunoglobulin heavy variable 4-34
chr11_+_118304721 3.27 ENST00000361763.9
CD3E
CD3e molecule
chr19_+_3178756 3.25 ENST00000246115.5
S1PR4
sphingosine-1-phosphate receptor 4
chr8_-_132760548 3.23 ENST00000519187.5
ENST00000523829.5
ENST00000677595.1
ENST00000356838.7
ENST00000377901.8
ENST00000519304.1
TMEM71
transmembrane protein 71
chr10_+_79610932 3.19 ENST00000428376.6
ENST00000398636.8
ENST00000419470.6
ENST00000429958.5
SFTPA1
surfactant protein A1
chr15_+_81296913 3.18 ENST00000394652.6
IL16
interleukin 16
chrX_-_71111448 3.05 ENST00000456850.6
ENST00000473378.1
ENST00000374202.7
ENST00000374188.7
IL2RG
interleukin 2 receptor subunit gamma
chr1_+_203765168 3.02 ENST00000367217.5
ENST00000442561.7
LAX1
lymphocyte transmembrane adaptor 1
chr5_-_139482685 2.97 ENST00000651565.1
STING1
stimulator of interferon response cGAMP interactor 1
chr10_-_70602687 2.90 ENST00000638674.1
PRF1
perforin 1
chr14_-_106349792 2.88 ENST00000438142.3
IGHV4-31
immunoglobulin heavy variable 4-31
chr22_+_22758698 2.85 ENST00000390312.2
IGLV2-14
immunoglobulin lambda variable 2-14
chr6_-_32816910 2.83 ENST00000447394.1
ENST00000438763.7
HLA-DOB
major histocompatibility complex, class II, DO beta
chr16_+_28985043 2.81 ENST00000395456.7
ENST00000564277.5
ENST00000630764.2
ENST00000354453.7
LAT
linker for activation of T cells
chr5_+_35856883 2.80 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
IL7R
interleukin 7 receptor
chr1_-_161069857 2.77 ENST00000368013.8
ARHGAP30
Rho GTPase activating protein 30
chr8_+_73991345 2.72 ENST00000284818.7
ENST00000518893.1
LY96
lymphocyte antigen 96
chr5_-_139482714 2.67 ENST00000652543.1
STING1
stimulator of interferon response cGAMP interactor 1
chr14_-_106012390 2.60 ENST00000455737.2
IGHV4-4
immunoglobulin heavy variable 4-4
chr14_+_88005128 2.58 ENST00000267549.5
GPR65
G protein-coupled receptor 65
chr4_+_40196907 2.56 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
RHOH
ras homolog family member H
chr5_-_139482341 2.51 ENST00000651699.1
STING1
stimulator of interferon response cGAMP interactor 1
chr1_-_153544997 2.49 ENST00000368715.5
S100A4
S100 calcium binding protein A4
chr16_+_30472733 2.46 ENST00000356798.11
ENST00000433423.2
ITGAL
integrin subunit alpha L
chr5_-_139482741 2.44 ENST00000330794.9
STING1
stimulator of interferon response cGAMP interactor 1
chr5_+_134115563 2.34 ENST00000517851.5
ENST00000521639.5
ENST00000522375.5
ENST00000378560.8
ENST00000520958.5
ENST00000518915.5
ENST00000395023.5
TCF7
transcription factor 7
chr14_-_106130061 2.29 ENST00000390602.3
IGHV3-13
immunoglobulin heavy variable 3-13
chr17_-_64020566 2.26 ENST00000578313.5
ENST00000584084.1
ENST00000579687.5
ENST00000578379.5
ENST00000578892.5
ENST00000579788.6
ENST00000412356.5
ENST00000418105.5
ICAM2
intercellular adhesion molecule 2
chrX_+_129779930 2.21 ENST00000356892.4
SASH3
SAM and SH3 domain containing 3
chrX_+_79144664 2.19 ENST00000645147.2
GPR174
G protein-coupled receptor 174
chr16_+_30472700 2.19 ENST00000358164.9
ITGAL
integrin subunit alpha L
chr7_-_3043838 2.13 ENST00000356408.3
ENST00000396946.9
CARD11
caspase recruitment domain family member 11
chr16_+_28985251 2.13 ENST00000360872.9
ENST00000566177.5
LAT
linker for activation of T cells
chr22_-_37149900 2.13 ENST00000216223.10
IL2RB
interleukin 2 receptor subunit beta
chr15_+_88635626 2.11 ENST00000379224.10
ISG20
interferon stimulated exonuclease gene 20
chr1_+_153357846 2.07 ENST00000368738.4
S100A9
S100 calcium binding protein A9
chr19_+_35902486 2.05 ENST00000246551.9
ENST00000437550.2
HCST
hematopoietic cell signal transducer
chr22_+_22734577 2.05 ENST00000390310.3
IGLV2-18
immunoglobulin lambda variable 2-18
chr1_+_32274111 2.04 ENST00000619559.4
ENST00000461712.6
ENST00000373562.7
ENST00000477031.6
ENST00000373557.6
ENST00000333070.4
LCK
LCK proto-oncogene, Src family tyrosine kinase
chr16_+_27313879 2.03 ENST00000562142.5
ENST00000561742.5
ENST00000543915.6
ENST00000395762.7
ENST00000563002.5
IL4R
interleukin 4 receptor
chr11_-_64744811 2.03 ENST00000377497.7
ENST00000377487.5
ENST00000430645.1
RASGRP2
RAS guanyl releasing protein 2
chr11_+_65879791 1.98 ENST00000528419.6
ENST00000307886.8
ENST00000526034.2
ENST00000679584.1
ENST00000680443.1
ENST00000680670.1
CTSW
cathepsin W
chr17_-_19387170 1.97 ENST00000395592.6
ENST00000299610.5
MFAP4
microfibril associated protein 4
chr1_+_209756032 1.94 ENST00000400959.7
ENST00000367025.8
TRAF3IP3
TRAF3 interacting protein 3
chr1_-_160711803 1.92 ENST00000368045.3
ENST00000368046.8
ENST00000613788.1
CD48
CD48 molecule
chr14_-_100376251 1.92 ENST00000556645.5
ENST00000556209.5
ENST00000556504.5
ENST00000556435.5
ENST00000554772.5
ENST00000553581.1
ENST00000553769.6
ENST00000554605.5
ENST00000557722.5
ENST00000553413.5
ENST00000553524.5
ENST00000358655.8
WARS1
tryptophanyl-tRNA synthetase 1
chr17_-_78128731 1.91 ENST00000592063.5
ENST00000590602.6
ENST00000589271.5
TMC6
transmembrane channel like 6
chr19_-_17847962 1.87 ENST00000458235.7
ENST00000534444.1
JAK3
Janus kinase 3
chr1_-_161069962 1.86 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chr14_-_106791226 1.84 ENST00000433072.2
IGHV3-72
immunoglobulin heavy variable 3-72
chr19_-_10335773 1.84 ENST00000592439.1
ICAM3
intercellular adhesion molecule 3
chr3_+_148865288 1.83 ENST00000296046.4
CPA3
carboxypeptidase A3
chr1_+_209756149 1.79 ENST00000367026.7
TRAF3IP3
TRAF3 interacting protein 3
chr17_-_64398391 1.79 ENST00000569967.1
PECAM1
platelet and endothelial cell adhesion molecule 1
chr1_-_167090370 1.79 ENST00000367868.4
GPA33
glycoprotein A33
chr16_+_28984795 1.79 ENST00000395461.7
LAT
linker for activation of T cells
chr1_-_156020789 1.75 ENST00000531917.5
ENST00000480567.5
ENST00000526212.2
ENST00000529008.5
ENST00000496742.5
ENST00000295702.9
SSR2
signal sequence receptor subunit 2
chr4_-_176792913 1.75 ENST00000618562.2
VEGFC
vascular endothelial growth factor C
chr1_-_32222322 1.74 ENST00000344461.7
ENST00000373593.5
ENST00000309777.11
TMEM234
transmembrane protein 234
chr14_+_105486867 1.73 ENST00000409393.6
ENST00000392531.4
CRIP1
cysteine rich protein 1
chr1_-_160647037 1.72 ENST00000302035.11
SLAMF1
signaling lymphocytic activation molecule family member 1
chr15_-_21742799 1.70 ENST00000622410.2
ENSG00000278263.2
novel protein, identical to IGHV4-4
chr3_+_32951636 1.69 ENST00000330953.6
CCR4
C-C motif chemokine receptor 4
chr19_-_7747511 1.69 ENST00000593660.5
ENST00000204801.12
ENST00000315591.12
ENST00000354397.10
ENST00000394161.9
ENST00000593821.5
ENST00000602261.5
ENST00000601256.1
ENST00000601951.5
ENST00000315599.12
CD209
CD209 molecule
chr5_-_141958174 1.68 ENST00000231484.4
PCDH12
protocadherin 12
chr6_-_132763424 1.67 ENST00000532012.1
ENST00000525270.5
ENST00000530536.5
ENST00000524919.5
VNN2
vanin 2
chr21_-_44920892 1.66 ENST00000397846.7
ENST00000652462.1
ENST00000302347.10
ENST00000524251.1
ITGB2
integrin subunit beta 2
chr1_+_209768482 1.66 ENST00000367023.5
TRAF3IP3
TRAF3 interacting protein 3
chr19_+_1077394 1.65 ENST00000590577.2
ARHGAP45
Rho GTPase activating protein 45
chr17_-_3964415 1.64 ENST00000397043.7
ENST00000397035.7
ENST00000397041.8
ATP2A3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr17_-_64020544 1.63 ENST00000583366.5
ICAM2
intercellular adhesion molecule 2
chr4_-_5019437 1.63 ENST00000506508.1
ENST00000509419.1
ENST00000307746.9
CYTL1
cytokine like 1
chr14_+_22052503 1.62 ENST00000390449.3
TRAV21
T cell receptor alpha variable 21
chr1_-_153550083 1.62 ENST00000368714.1
S100A4
S100 calcium binding protein A4
chr5_+_96876480 1.62 ENST00000437043.8
ENST00000379904.8
ERAP2
endoplasmic reticulum aminopeptidase 2
chr3_+_46987972 1.61 ENST00000651747.1
NBEAL2
neurobeachin like 2
chrX_+_48683763 1.61 ENST00000376701.5
WAS
WASP actin nucleation promoting factor
chr15_-_22185402 1.59 ENST00000557788.2
IGHV4OR15-8
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr4_-_73998669 1.59 ENST00000296027.5
CXCL5
C-X-C motif chemokine ligand 5
chr10_+_69088096 1.59 ENST00000242465.4
SRGN
serglycin
chr19_+_41549510 1.59 ENST00000407170.6
ENST00000601116.5
ENST00000595395.1
CEACAM21
ENSG00000268027.5
CEA cell adhesion molecule 21
novel transcript, sense intronic to CEACAM21
chr20_+_3786772 1.58 ENST00000344256.10
ENST00000379598.9
CDC25B
cell division cycle 25B
chr12_-_53207271 1.57 ENST00000552972.5
ENST00000422257.7
ITGB7
integrin subunit beta 7
chr17_-_78128778 1.56 ENST00000589553.5
TMC6
transmembrane channel like 6
chr12_-_53207241 1.56 ENST00000267082.10
ENST00000549086.2
ITGB7
integrin subunit beta 7
chr4_+_89894846 1.56 ENST00000264790.7
MMRN1
multimerin 1
chr7_+_50308672 1.55 ENST00000439701.2
ENST00000438033.5
ENST00000492782.6
IKZF1
IKAROS family zinc finger 1
chr16_+_66604100 1.55 ENST00000562357.5
ENST00000562707.5
ENST00000361909.8
ENST00000460097.5
ENST00000565666.5
CMTM3
CKLF like MARVEL transmembrane domain containing 3
chr2_-_187448244 1.55 ENST00000392370.8
ENST00000410068.5
ENST00000447403.5
ENST00000410102.5
CALCRL
calcitonin receptor like receptor
chr8_+_81280527 1.54 ENST00000297258.11
FABP5
fatty acid binding protein 5
chr4_-_152679984 1.54 ENST00000304385.8
ENST00000504064.1
TMEM154
transmembrane protein 154
chr2_+_203706475 1.53 ENST00000374481.7
ENST00000458610.6
CD28
CD28 molecule
chr2_-_174597728 1.53 ENST00000409891.5
ENST00000410117.5
WIPF1
WAS/WASL interacting protein family member 1
chr20_+_36573589 1.53 ENST00000373872.9
ENST00000650844.1
TGIF2
TGFB induced factor homeobox 2
chr17_+_7336587 1.53 ENST00000575425.1
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr19_-_10194898 1.53 ENST00000359526.9
ENST00000679103.1
ENST00000676610.1
ENST00000678804.1
ENST00000679313.1
ENST00000677946.1
DNMT1
DNA methyltransferase 1
chr6_+_33272067 1.53 ENST00000474973.5
ENST00000439602.7
RPS18
ribosomal protein S18
chr1_-_159923717 1.53 ENST00000368096.5
TAGLN2
transgelin 2
chr9_-_114387973 1.52 ENST00000374088.8
AKNA
AT-hook transcription factor
chr1_+_23959109 1.52 ENST00000471915.5
PNRC2
proline rich nuclear receptor coactivator 2
chr7_+_150716603 1.50 ENST00000307194.6
ENST00000611999.4
GIMAP1
GIMAP1-GIMAP5
GTPase, IMAP family member 1
GIMAP1-GIMAP5 readthrough
chr17_-_7080231 1.50 ENST00000576617.5
ENST00000416562.7
CLEC10A
C-type lectin domain containing 10A
chrX_+_15500800 1.50 ENST00000348343.11
BMX
BMX non-receptor tyrosine kinase
chr16_+_28985095 1.49 ENST00000454369.6
LAT
linker for activation of T cells
chr20_-_23086316 1.49 ENST00000246006.5
CD93
CD93 molecule
chr19_+_13151975 1.49 ENST00000588173.1
IER2
immediate early response 2
chr5_-_139462701 1.48 ENST00000618155.3
ECSCR
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr1_+_209768597 1.47 ENST00000487271.5
ENST00000477431.1
TRAF3IP3
TRAF3 interacting protein 3
chr1_-_85276467 1.47 ENST00000648566.1
BCL10
BCL10 immune signaling adaptor
chr17_-_35880350 1.44 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
CCL5
C-C motif chemokine ligand 5
chr16_-_30382805 1.44 ENST00000321367.7
ENST00000652617.1
SEPTIN1
septin 1
chr8_-_132760624 1.43 ENST00000522334.5
ENST00000519016.5
TMEM71
transmembrane protein 71
chr2_+_233059838 1.42 ENST00000359570.9
INPP5D
inositol polyphosphate-5-phosphatase D
chr17_-_63699730 1.42 ENST00000578061.5
LIMD2
LIM domain containing 2
chr4_+_40197023 1.41 ENST00000381799.10
RHOH
ras homolog family member H
chr17_-_45432916 1.40 ENST00000290470.3
ARHGAP27
Rho GTPase activating protein 27
chr2_-_197310767 1.40 ENST00000282272.15
ENST00000409153.5
ENST00000409919.5
ANKRD44
ankyrin repeat domain 44
chr14_+_63204859 1.39 ENST00000555125.1
RHOJ
ras homolog family member J
chr12_-_57479552 1.39 ENST00000424809.6
ARHGAP9
Rho GTPase activating protein 9
chr17_-_3964458 1.38 ENST00000309890.11
ATP2A3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr19_-_10339610 1.37 ENST00000589261.5
ENST00000160262.10
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
ICAM3
intercellular adhesion molecule 3
chr21_-_44920855 1.37 ENST00000397854.7
ITGB2
integrin subunit beta 2
chr4_+_108620616 1.37 ENST00000506397.5
ENST00000394668.2
RPL34
ribosomal protein L34
chr12_-_57479848 1.37 ENST00000393791.8
ENST00000552249.1
ARHGAP9
Rho GTPase activating protein 9
chr2_-_237414157 1.37 ENST00000295550.9
ENST00000353578.9
ENST00000392004.7
ENST00000433762.1
ENST00000392003.6
COL6A3
collagen type VI alpha 3 chain
chr4_+_108620584 1.36 ENST00000394665.5
RPL34
ribosomal protein L34
chr2_-_174598206 1.36 ENST00000392546.6
ENST00000436221.1
WIPF1
WAS/WASL interacting protein family member 1
chr5_-_139482285 1.35 ENST00000652110.1
STING1
stimulator of interferon response cGAMP interactor 1
chr1_+_158931539 1.35 ENST00000368140.6
ENST00000368138.7
ENST00000392254.6
ENST00000392252.7
ENST00000368135.4
PYHIN1
pyrin and HIN domain family member 1
chr1_-_160646958 1.34 ENST00000538290.2
SLAMF1
signaling lymphocytic activation molecule family member 1
chr2_-_197310646 1.34 ENST00000647377.1
ANKRD44
ankyrin repeat domain 44
chr15_+_76995118 1.34 ENST00000558012.6
ENST00000379595.7
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr21_+_42653734 1.33 ENST00000335512.8
ENST00000328862.10
ENST00000335440.10
ENST00000380328.6
ENST00000398225.7
ENST00000398227.7
ENST00000398229.7
ENST00000398232.7
ENST00000398234.7
ENST00000398236.7
ENST00000349112.7
ENST00000398224.3
PDE9A
phosphodiesterase 9A
chr1_-_202161575 1.33 ENST00000309017.7
ENST00000477554.5
ENST00000492451.1
PTPN7
protein tyrosine phosphatase non-receptor type 7
chr12_+_10307950 1.33 ENST00000543420.5
ENST00000543777.5
KLRD1
killer cell lectin like receptor D1
chr17_+_8310814 1.33 ENST00000579439.5
ENST00000421050.2
ARHGEF15
Rho guanine nucleotide exchange factor 15
chr2_+_203706614 1.32 ENST00000324106.9
CD28
CD28 molecule
chr19_-_46625037 1.32 ENST00000596260.1
ENST00000594275.1
ENST00000597185.1
ENST00000598865.5
ENST00000291294.7
PTGIR
prostaglandin I2 receptor
chr14_-_106658251 1.32 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr11_-_64742937 1.32 ENST00000394428.5
ENST00000394429.5
RASGRP2
RAS guanyl releasing protein 2
chr11_-_104164126 1.31 ENST00000393158.7
PDGFD
platelet derived growth factor D
chr14_+_22007503 1.31 ENST00000390447.3
TRAV19
T cell receptor alpha variable 19
chr3_-_121660892 1.31 ENST00000428394.6
ENST00000314583.8
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr19_+_797392 1.31 ENST00000627714.2
ENST00000349038.8
ENST00000586481.5
PTBP1
polypyrimidine tract binding protein 1
chr1_-_36323593 1.30 ENST00000490466.2
EVA1B
eva-1 homolog B
chr11_+_64206663 1.30 ENST00000544997.5
ENST00000345728.10
ENST00000279227.9
FERMT3
fermitin family member 3
chr1_-_92486916 1.30 ENST00000294702.6
GFI1
growth factor independent 1 transcriptional repressor
chr11_-_417385 1.30 ENST00000332725.7
SIGIRR
single Ig and TIR domain containing
chr19_-_19643597 1.29 ENST00000587205.1
ENST00000203556.9
GMIP
GEM interacting protein
chr2_-_174597795 1.29 ENST00000679041.1
WIPF1
WAS/WASL interacting protein family member 1
chr19_-_11577632 1.29 ENST00000590420.1
ENST00000648477.1
ACP5
acid phosphatase 5, tartrate resistant
chr19_+_50418930 1.28 ENST00000439922.6
ENST00000595883.6
ENST00000597855.5
ENST00000596074.5
ENST00000594685.1
ENST00000270632.7
SPIB
Spi-B transcription factor
chr2_-_237414127 1.28 ENST00000472056.5
COL6A3
collagen type VI alpha 3 chain
chr12_+_6789508 1.28 ENST00000011653.9
ENST00000541982.5
ENST00000539492.1
CD4
CD4 molecule
chr3_+_132597260 1.27 ENST00000249887.3
ACKR4
atypical chemokine receptor 4
chr19_+_1026566 1.27 ENST00000562015.5
ENST00000263097.9
ENST00000348419.7
ENST00000565096.6
ENST00000562958.6
ENST00000568865.3
ENST00000606983.5
ENST00000562075.6
ENST00000607102.1
CNN2
calponin 2
chr2_-_187554473 1.27 ENST00000453013.5
ENST00000417013.5
TFPI
tissue factor pathway inhibitor
chr2_+_233060295 1.27 ENST00000445964.6
INPP5D
inositol polyphosphate-5-phosphatase D
chr14_+_63204436 1.27 ENST00000316754.8
RHOJ
ras homolog family member J
chr14_+_55129242 1.26 ENST00000254301.14
ENST00000554715.1
LGALS3
galectin 3
chr2_+_201116396 1.26 ENST00000395148.6
CFLAR
CASP8 and FADD like apoptosis regulator
chr12_+_10307818 1.26 ENST00000350274.9
ENST00000336164.9
KLRD1
killer cell lectin like receptor D1
chr5_+_119333151 1.26 ENST00000513374.1
TNFAIP8
TNF alpha induced protein 8
chr1_-_156816841 1.25 ENST00000368199.8
ENST00000392306.2
SH2D2A
SH2 domain containing 2A
chr16_-_50681289 1.25 ENST00000423026.6
ENST00000330943.9
SNX20
sorting nexin 20
chr1_-_27366917 1.25 ENST00000357582.3
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr2_+_68365274 1.25 ENST00000234313.8
PLEK
pleckstrin
chr19_+_40775511 1.24 ENST00000263369.4
ENST00000597140.5
MIA
MIA SH3 domain containing
chr12_-_10098977 1.24 ENST00000315330.8
ENST00000457018.6
CLEC1A
C-type lectin domain family 1 member A
chr17_-_55732074 1.24 ENST00000575734.5
TMEM100
transmembrane protein 100
chr19_+_797443 1.24 ENST00000356948.11
ENST00000394601.8
ENST00000589575.5
ENST00000587191.3
PTBP1
polypyrimidine tract binding protein 1
chr12_+_8989535 1.24 ENST00000356986.8
KLRG1
killer cell lectin like receptor G1
chr7_+_93921720 1.23 ENST00000248564.6
GNG11
G protein subunit gamma 11
chr12_-_57478070 1.23 ENST00000549602.1
ENST00000430041.6
ARHGAP9
Rho GTPase activating protein 9
chr7_-_150632333 1.22 ENST00000493969.2
ENST00000328902.9
GIMAP6
GTPase, IMAP family member 6
chr19_+_7677082 1.22 ENST00000597445.1
MCEMP1
mast cell expressed membrane protein 1
chr2_-_187554351 1.22 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
TFPI
tissue factor pathway inhibitor
chr7_-_150632644 1.21 ENST00000618759.4
GIMAP6
GTPase, IMAP family member 6
chr17_-_63699162 1.20 ENST00000582055.1
LIMD2
LIM domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of FLI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 9.9 GO:0002357 defense response to tumor cell(GO:0002357)
1.3 6.6 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.1 7.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
1.1 3.2 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
1.0 4.0 GO:0035744 T-helper 1 cell cytokine production(GO:0035744)
0.9 4.7 GO:0039507 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.9 2.8 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.9 4.3 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.7 2.8 GO:0046968 peptide antigen transport(GO:0046968)
0.7 2.1 GO:0061485 memory T cell proliferation(GO:0061485)
0.7 4.0 GO:0050904 diapedesis(GO:0050904)
0.7 2.7 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.6 3.8 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.6 3.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.6 1.2 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.6 1.8 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.6 2.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.6 1.7 GO:1900098 epithelial cell differentiation involved in salivary gland development(GO:0060690) epithelial cell maturation involved in salivary gland development(GO:0060691) regulation of plasma cell differentiation(GO:1900098) positive regulation of plasma cell differentiation(GO:1900100) positive regulation of lactation(GO:1903489)
0.5 3.2 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.5 1.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.5 2.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 2.6 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.5 2.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.5 0.5 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.5 5.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.5 1.9 GO:0052509 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.5 1.9 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.5 1.4 GO:1900081 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.5 1.4 GO:2000449 CD8-positive, alpha-beta T cell extravasation(GO:0035697) CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of T cell extravasation(GO:2000407) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.4 6.3 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.4 1.3 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.4 1.7 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.4 8.9 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.4 1.3 GO:0035922 pulmonary valve formation(GO:0003193) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.4 1.7 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.4 3.3 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.4 6.4 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.4 1.6 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.4 2.7 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.4 1.9 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.4 1.1 GO:0021503 neural fold bending(GO:0021503)
0.4 1.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.4 1.4 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.4 1.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.4 1.8 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.3 1.0 GO:0061011 hepatic duct development(GO:0061011)
0.3 1.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 1.0 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.3 1.0 GO:0019417 sulfur oxidation(GO:0019417)
0.3 1.6 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.3 0.9 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.3 2.7 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.3 0.9 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.3 2.3 GO:0030538 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.3 0.9 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.3 0.9 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.3 1.7 GO:0071461 cellular response to redox state(GO:0071461)
0.3 1.4 GO:0033590 response to cobalamin(GO:0033590)
0.3 1.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.3 2.3 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.2 1.2 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.2 0.7 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.2 1.5 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.2 2.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 0.7 GO:0019085 early viral transcription(GO:0019085)
0.2 1.2 GO:0009624 response to nematode(GO:0009624)
0.2 0.5 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.2 1.2 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2 1.8 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.2 4.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.2 0.7 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 0.7 GO:0034769 basement membrane disassembly(GO:0034769)
0.2 0.9 GO:0001777 T cell homeostatic proliferation(GO:0001777)
0.2 3.2 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.2 1.6 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 37.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 1.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.2 1.3 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.2 0.4 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
0.2 1.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.2 1.8 GO:0090116 C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 2.7 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 1.0 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.2 2.0 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.2 3.2 GO:0008228 opsonization(GO:0008228)
0.2 1.2 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.2 2.6 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 1.0 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.2 1.9 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 1.0 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 0.4 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.2 1.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.6 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 2.4 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 0.5 GO:0098506 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349) DNA 3' dephosphorylation(GO:0098503) DNA 3' dephosphorylation involved in DNA repair(GO:0098504) polynucleotide 3' dephosphorylation(GO:0098506)
0.2 0.7 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.2 0.5 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.2 1.6 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 1.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 1.4 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.2 3.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.2 1.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 2.4 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.2 0.5 GO:0032827 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.2 0.5 GO:0036451 cap mRNA methylation(GO:0036451)
0.2 2.7 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 2.2 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2 0.7 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2 1.0 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 0.8 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.2 1.0 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.2 0.5 GO:0006667 sphinganine metabolic process(GO:0006667)
0.2 1.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 2.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 0.5 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.2 0.5 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.2 2.9 GO:0022417 protein maturation by protein folding(GO:0022417)
0.2 0.3 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.8 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.2 2.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 0.5 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.2 1.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 0.5 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.2 0.5 GO:0036245 cellular response to menadione(GO:0036245)
0.2 1.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2 0.6 GO:0009956 radial pattern formation(GO:0009956)
0.2 2.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 0.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 0.5 GO:0051414 response to cortisol(GO:0051414)
0.1 0.6 GO:0044691 tooth eruption(GO:0044691)
0.1 4.1 GO:0019081 viral translation(GO:0019081)
0.1 0.9 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 3.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.9 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 23.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 0.4 GO:0015734 taurine transport(GO:0015734)
0.1 0.9 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 1.7 GO:0070836 caveola assembly(GO:0070836)
0.1 1.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.6 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.1 1.1 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.6 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.7 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 1.9 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.1 0.9 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.9 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 1.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 0.4 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 1.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.2 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.4 GO:0060352 cell adhesion molecule production(GO:0060352)
0.1 1.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.5 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.1 GO:0002584 negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
0.1 0.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.6 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.6 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1 1.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.7 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 1.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.5 GO:0033320 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.1 1.1 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.9 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.4 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.7 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 2.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 3.6 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 0.8 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 2.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 2.6 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 5.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.9 GO:0072757 cellular response to camptothecin(GO:0072757)
0.1 1.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.3 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.6 GO:0010159 specification of organ position(GO:0010159)
0.1 12.3 GO:0045576 mast cell activation(GO:0045576)
0.1 0.9 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.7 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 9.3 GO:0042100 B cell proliferation(GO:0042100)
0.1 0.3 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 1.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.2 GO:1905237 response to cyclosporin A(GO:1905237)
0.1 0.3 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 3.5 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 2.6 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 3.0 GO:0002467 germinal center formation(GO:0002467)
0.1 1.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.5 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 1.6 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.1 1.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 1.0 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.1 1.5 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.6 GO:0039526 suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526)
0.1 0.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 2.0 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 1.4 GO:1902624 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.1 2.8 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.3 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 7.4 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.1 0.5 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.1 0.7 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 1.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.5 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 1.3 GO:0043383 negative T cell selection(GO:0043383)
0.1 1.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 1.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 4.3 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 1.1 GO:0033227 dsRNA transport(GO:0033227)
0.1 1.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.4 GO:0039656 modulation by virus of host gene expression(GO:0039656) modification by virus of host mRNA processing(GO:0046778)
0.1 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.5 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 1.4 GO:0007144 female meiosis I(GO:0007144)
0.1 0.6 GO:0046061 dATP catabolic process(GO:0046061)
0.1 0.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.1 1.0 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 1.0 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 5.0 GO:0006968 cellular defense response(GO:0006968)
0.1 0.1 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.1 1.0 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 0.3 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.9 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.3 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 0.9 GO:0033622 integrin activation(GO:0033622)
0.1 0.5 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.1 0.5 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.8 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.3 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.7 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516)
0.1 0.4 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 0.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.3 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 1.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 1.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.4 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.4 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 0.3 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.4 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 1.9 GO:0043101 purine-containing compound salvage(GO:0043101)
0.1 0.4 GO:0070269 pyroptosis(GO:0070269)
0.1 1.4 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 2.2 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1 0.6 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 0.5 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 0.6 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.2 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.1 0.7 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 3.0 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 0.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 1.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.1 1.1 GO:0036010 protein localization to endosome(GO:0036010)
0.1 0.2 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.1 0.3 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 4.8 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 0.7 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.1 0.4 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.1 GO:0001878 response to yeast(GO:0001878)
0.1 1.0 GO:0042832 defense response to protozoan(GO:0042832)
0.1 1.8 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.2 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.1 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 1.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.2 GO:0032679 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.2 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 1.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.1 GO:1901623 regulation of lymphocyte chemotaxis(GO:1901623)
0.1 0.4 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 1.1 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.1 GO:0036323 vascular endothelial growth factor receptor-1 signaling pathway(GO:0036323)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.5 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.3 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.5 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 1.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.6 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 1.5 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 6.3 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.9 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 1.1 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.3 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.5 GO:0044557 relaxation of smooth muscle(GO:0044557)
0.0 1.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.9 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 1.0 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.6 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 1.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.2 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.3 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.7 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:1902824 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 1.9 GO:0002819 regulation of adaptive immune response(GO:0002819)
0.0 0.4 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0 0.5 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.7 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 3.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.8 GO:0001945 lymph vessel development(GO:0001945)
0.0 1.0 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 1.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.4 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 2.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 1.2 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 26.5 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.2 GO:0051459 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 3.1 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.9 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.2 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0 7.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.1 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.0 0.9 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 1.6 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0018008 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 2.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 3.7 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:0035588 G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 1.4 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 0.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 4.3 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.3 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.3 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.0 0.1 GO:1904732 regulation of electron carrier activity(GO:1904732)
0.0 0.2 GO:2001044 regulation of integrin-mediated signaling pathway(GO:2001044)
0.0 0.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0044340 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 1.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 5.6 GO:0008154 actin polymerization or depolymerization(GO:0008154)
0.0 0.1 GO:0071402 cellular response to lipoprotein particle stimulus(GO:0071402)
0.0 2.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.5 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.2 GO:0018202 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0 0.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.5 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 2.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.5 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 1.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.9 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.3 GO:0018095 sperm axoneme assembly(GO:0007288) protein polyglutamylation(GO:0018095)
0.0 0.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 1.1 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.3 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.3 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.4 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 1.1 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.3 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.4 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.1 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.0 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.6 GO:0048265 response to pain(GO:0048265)
0.0 0.5 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.0 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.0 0.4 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.4 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.5 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.3 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.3 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.6 GO:0030193 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.6 GO:0051058 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.4 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.0 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.5 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.7 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.3 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 9.9 GO:0044194 cytolytic granule(GO:0044194)
0.8 8.5 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.8 3.9 GO:0019815 B cell receptor complex(GO:0019815)
0.6 3.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.6 20.0 GO:0042101 T cell receptor complex(GO:0042101)
0.5 2.6 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.4 0.9 GO:1990617 CHOP-ATF4 complex(GO:1990617)
0.4 27.9 GO:0001772 immunological synapse(GO:0001772)
0.4 10.1 GO:0097342 ripoptosome(GO:0097342)
0.3 7.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 2.1 GO:0014802 terminal cisterna(GO:0014802)
0.3 1.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 1.9 GO:1902560 GMP reductase complex(GO:1902560)
0.3 2.6 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.3 3.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.3 2.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 1.8 GO:0036021 endolysosome lumen(GO:0036021)
0.2 6.8 GO:0042599 lamellar body(GO:0042599)
0.2 2.3 GO:0032010 phagolysosome(GO:0032010)
0.2 2.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 12.5 GO:0019814 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.2 0.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.2 1.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2 1.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 2.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.6 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 0.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 2.0 GO:0071953 elastic fiber(GO:0071953)
0.2 0.6 GO:0005606 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.2 1.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 2.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 2.5 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.2 0.5 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.2 1.4 GO:0043196 varicosity(GO:0043196)
0.2 0.8 GO:0005899 insulin receptor complex(GO:0005899)
0.2 2.7 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.6 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 2.0 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.9 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 2.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 2.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.3 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 0.8 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.4 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.1 1.9 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.0 GO:0005683 U7 snRNP(GO:0005683)
0.1 14.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.8 GO:0031523 Myb complex(GO:0031523)
0.1 0.4 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.4 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.3 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.7 GO:0089701 U2AF(GO:0089701)
0.1 5.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.6 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 3.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.3 GO:0009346 citrate lyase complex(GO:0009346)
0.1 0.5 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.1 1.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.8 GO:0005687 U4 snRNP(GO:0005687)
0.1 34.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 12.6 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 0.3 GO:0036117 hyaluranon cable(GO:0036117)
0.1 7.9 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 0.9 GO:0032009 early phagosome(GO:0032009)
0.1 0.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.9 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.6 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 2.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.8 GO:0098560 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.3 GO:0032449 CBM complex(GO:0032449)
0.1 0.6 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.8 GO:0051286 cell tip(GO:0051286)
0.1 1.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.6 GO:0042588 zymogen granule(GO:0042588)
0.1 1.4 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 0.4 GO:1990462 omegasome(GO:1990462)
0.1 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 4.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.1 0.8 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 2.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 0.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 7.4 GO:0031091 platelet alpha granule(GO:0031091)
0.1 0.3 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 0.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 13.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.3 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.4 GO:0097443 sorting endosome(GO:0097443)
0.1 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 2.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 6.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.3 GO:0060171 stereocilium membrane(GO:0060171)
0.0 3.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 1.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 5.5 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 3.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 2.0 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.6 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 5.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 5.7 GO:0034774 secretory granule lumen(GO:0034774)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 4.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.6 GO:0036019 endolysosome(GO:0036019)
0.0 0.1 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.0 2.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 1.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 2.3 GO:0072562 blood microparticle(GO:0072562)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 3.4 GO:0001650 fibrillar center(GO:0001650)
0.0 1.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.0 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 2.0 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 4.4 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 4.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0004917 interleukin-7 receptor activity(GO:0004917)
1.2 2.5 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.9 6.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.9 7.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.8 8.5 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.7 6.6 GO:0042608 T cell receptor binding(GO:0042608)
0.7 2.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.7 2.8 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.7 3.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.6 2.5 GO:0032089 NACHT domain binding(GO:0032089)
0.6 3.0 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.5 2.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.5 11.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.5 1.0 GO:0019957 C-C chemokine binding(GO:0019957)
0.5 1.9 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.5 1.4 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.4 1.5 GO:0004948 calcitonin receptor activity(GO:0004948)
0.4 2.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.4 1.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.4 2.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3 2.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 2.7 GO:0004974 leukotriene receptor activity(GO:0004974)
0.3 1.9 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.3 0.6 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
0.3 2.1 GO:0019862 IgA binding(GO:0019862)
0.3 1.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.3 2.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 1.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 4.0 GO:0051434 BH3 domain binding(GO:0051434)
0.3 1.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.3 8.5 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.3 1.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.2 0.7 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 1.5 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 0.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.2 1.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 1.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 0.7 GO:0004615 phosphomannomutase activity(GO:0004615)
0.2 5.2 GO:0005522 profilin binding(GO:0005522)
0.2 0.7 GO:0005128 erythropoietin receptor binding(GO:0005128) interleukin-3 receptor binding(GO:0005135)
0.2 1.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 58.3 GO:0003823 antigen binding(GO:0003823)
0.2 0.6 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.2 6.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 6.7 GO:0022829 wide pore channel activity(GO:0022829)
0.2 3.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 1.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 2.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 1.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.2 0.6 GO:0044713 GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
0.2 1.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.5 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.2 2.5 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 1.7 GO:0004064 arylesterase activity(GO:0004064)
0.2 0.5 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.2 1.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 2.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 1.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.2 1.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 2.3 GO:0050700 CARD domain binding(GO:0050700)
0.2 0.5 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 1.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 0.3 GO:0031691 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762)
0.2 0.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.2 0.5 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.2 7.9 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 0.9 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.4 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.1 0.4 GO:0005368 taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
0.1 4.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 5.0 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 3.3 GO:0048185 activin binding(GO:0048185)
0.1 0.5 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1 0.5 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 1.2 GO:0035500 MH2 domain binding(GO:0035500)
0.1 1.2 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.3 GO:0019863 IgE binding(GO:0019863)
0.1 1.8 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 1.4 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.4 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 4.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.5 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.1 1.0 GO:0032810 sterol response element binding(GO:0032810)
0.1 2.9 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 2.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.9 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 5.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.9 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 1.0 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 1.4 GO:0008142 oxysterol binding(GO:0008142)
0.1 4.5 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.7 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 1.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.8 GO:0050733 RS domain binding(GO:0050733)
0.1 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 6.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.0 GO:0019534 toxin transporter activity(GO:0019534)
0.1 1.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 3.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.3 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.1 0.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 2.8 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 9.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.5 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.3 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 2.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.4 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.4 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.8 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 0.7 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.4 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.4 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.3 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.0 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.9 GO:0042731 PH domain binding(GO:0042731)
0.1 0.6 GO:0042806 fucose binding(GO:0042806)
0.1 0.3 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 1.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 4.1 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.8 GO:0045159 myosin II binding(GO:0045159)
0.1 0.7 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 5.7 GO:0019843 rRNA binding(GO:0019843)
0.1 2.2 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 1.8 GO:0042287 MHC protein binding(GO:0042287)
0.1 1.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.3 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.6 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 1.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 2.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.6 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 1.6 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 2.1 GO:0043394 proteoglycan binding(GO:0043394)
0.1 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.3 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.9 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 2.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.5 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 2.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.3 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 0.5 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 0.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 2.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.4 GO:0031005 filamin binding(GO:0031005)
0.1 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.3 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 1.1 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.2 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.2 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.1 10.6 GO:0005178 integrin binding(GO:0005178)
0.1 0.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 2.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 5.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0036326 VEGF-A-activated receptor activity(GO:0036326) VEGF-B-activated receptor activity(GO:0036327) placental growth factor-activated receptor activity(GO:0036332)
0.0 0.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 1.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.8 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 1.4 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 1.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 3.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 2.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 1.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 1.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 5.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 1.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 14.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0032405 MutLalpha complex binding(GO:0032405)
0.0 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 10.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 14.4 GO:0005525 GTP binding(GO:0005525)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.5 GO:0000150 recombinase activity(GO:0000150)
0.0 5.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 5.2 GO:0005125 cytokine activity(GO:0005125)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 2.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 3.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.3 GO:0008430 selenium binding(GO:0008430)
0.0 1.8 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.0 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.4 GO:0035326 enhancer binding(GO:0035326)
0.0 0.3 GO:0016208 AMP binding(GO:0016208)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0016531 metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.0 4.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 46.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.2 15.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 9.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 8.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 9.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.2 4.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.2 3.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 1.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 3.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 3.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 5.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 2.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 4.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 5.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 0.2 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 2.1 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 5.3 PID CD40 PATHWAY CD40/CD40L signaling
0.1 1.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 4.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 2.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 2.2 PID ARF 3PATHWAY Arf1 pathway
0.1 3.5 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 4.0 PID ENDOTHELIN PATHWAY Endothelins
0.1 1.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 9.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 5.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.3 PID RAS PATHWAY Regulation of Ras family activation
0.1 1.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 1.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.0 PID BCR 5PATHWAY BCR signaling pathway
0.1 1.2 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 1.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 1.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 3.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 11.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 17.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 2.3 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.7 PID ATM PATHWAY ATM pathway
0.0 0.7 PID INSULIN PATHWAY Insulin Pathway
0.0 0.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 2.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 2.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 7.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 14.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.4 11.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 7.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 2.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.3 4.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.3 9.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.3 5.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 27.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 1.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 0.9 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 8.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.2 7.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 0.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 4.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 2.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 5.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 21.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 2.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 2.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 5.6 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 1.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 3.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.2 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.1 1.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.8 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.1 5.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.6 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 18.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.0 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 3.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.1 REACTOME TRANSCRIPTION COUPLED NER TC NER Genes involved in Transcription-coupled NER (TC-NER)
0.0 2.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 2.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 2.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 2.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 3.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 5.9 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 7.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 2.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.1 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 4.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 2.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 4.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 2.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.1 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 2.3 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.9 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 1.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling