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Illumina Body Map 2 (GSE30611)

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Results for FOSB

Z-value: 0.89

Motif logo

Transcription factors associated with FOSB

Gene Symbol Gene ID Gene Info
ENSG00000125740.14 FosB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSBhg38_v1_chr19_+_45470102_45470265-0.485.4e-03Click!

Activity profile of FOSB motif

Sorted Z-values of FOSB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_27282419 1.70 ENST00000380075.7
ENST00000296098.4
tripartite motif containing 54
chr8_-_17895403 1.54 ENST00000381840.5
ENST00000398054.5
fibrinogen like 1
chr2_-_219308963 1.47 ENST00000423636.6
ENST00000442029.5
ENST00000412847.5
protein tyrosine phosphatase receptor type N
chr8_-_17895487 1.47 ENST00000427924.5
ENST00000381841.4
fibrinogen like 1
chr20_-_653189 1.43 ENST00000381962.4
sulfiredoxin 1
chr9_-_114078293 1.41 ENST00000265132.8
alpha-1-microglobulin/bikunin precursor
chr17_+_4950147 1.38 ENST00000522301.5
enolase 3
chr7_+_116672357 1.36 ENST00000456159.1
MET proto-oncogene, receptor tyrosine kinase
chr11_-_102843597 1.26 ENST00000299855.10
matrix metallopeptidase 3
chr17_-_35063648 1.24 ENST00000394597.7
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr15_-_82952683 1.23 ENST00000450735.7
ENST00000304231.12
homer scaffold protein 2
chr1_+_169107883 1.19 ENST00000494797.1
ATPase Na+/K+ transporting subunit beta 1
chrX_-_155264471 1.15 ENST00000369454.4
RAB39B, member RAS oncogene family
chr4_-_23881282 1.10 ENST00000613098.4
PPARG coactivator 1 alpha
chr4_-_76898118 1.09 ENST00000334306.4
sosondowah ankyrin repeat domain family member B
chr15_-_34795541 1.08 ENST00000290378.6
actin alpha cardiac muscle 1
chr19_-_55370455 1.05 ENST00000264563.7
ENST00000585513.1
ENST00000590625.5
interleukin 11
chr18_-_76495191 1.04 ENST00000443185.7
zinc finger protein 516
chr10_+_133087883 1.02 ENST00000392607.8
adhesion G protein-coupled receptor A1
chr4_+_41981745 1.01 ENST00000333141.7
DDB1 and CUL4 associated factor 4 like 1
chr5_+_175861628 0.99 ENST00000509837.5
complexin 2
chr17_-_75154534 0.99 ENST00000356033.8
Jupiter microtubule associated homolog 1
chr14_+_93997296 0.98 ENST00000636493.2
coiled-coil domain containing 197
chr4_-_79408198 0.98 ENST00000358842.5
glycerol kinase 2
chr19_-_54188278 0.97 ENST00000449249.5
membrane bound O-acyltransferase domain containing 7
chr17_+_82359245 0.95 ENST00000333437.5
testis expressed 19
chr21_+_29300111 0.94 ENST00000451655.5
BTB domain and CNC homolog 1
chr7_-_98869920 0.94 ENST00000345589.4
transmembrane protein 130
chr15_+_40239420 0.94 ENST00000560346.5
p21 (RAC1) activated kinase 6
chr10_-_47491700 0.92 ENST00000452267.2
family with sequence similarity 25 member G
chr4_-_36244438 0.92 ENST00000303965.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_+_94026314 0.90 ENST00000203664.10
ENST00000553723.1
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr12_-_95996302 0.90 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
histidine ammonia-lyase
chr11_-_65382632 0.90 ENST00000294187.10
ENST00000398802.6
ENST00000530936.1
solute carrier family 25 member 45
chr12_-_120368069 0.89 ENST00000546985.1
musashi RNA binding protein 1
chr15_+_40239042 0.88 ENST00000558055.5
ENST00000455577.6
p21 (RAC1) activated kinase 6
chr19_-_35490456 0.83 ENST00000338897.4
ENST00000484218.6
keratinocyte differentiation associated protein
chr11_+_18599782 0.82 ENST00000634992.1
ENST00000635674.1
ENST00000511927.2
SPTY2D1 opposite strand
chr7_-_98870006 0.81 ENST00000339375.9
transmembrane protein 130
chr6_+_292050 0.81 ENST00000344450.9
dual specificity phosphatase 22
chr12_-_44921842 0.81 ENST00000552993.5
neural EGFL like 2
chr17_-_29140373 0.81 ENST00000533420.3
myosin XVIIIA
chr17_-_8118489 0.78 ENST00000380149.6
ENST00000448843.7
arachidonate lipoxygenase 3
chr16_-_72172135 0.78 ENST00000537465.5
ENST00000237353.15
polyamine modulated factor 1 binding protein 1
chr4_+_83536097 0.78 ENST00000395226.6
ENST00000264409.5
glycerol-3-phosphate acyltransferase 3
chr1_-_190474801 0.77 ENST00000445957.2
BMP/retinoic acid inducible neural specific 3
chr4_-_99657820 0.77 ENST00000511828.2
chromosome 4 open reading frame 54
chr13_-_41194485 0.77 ENST00000379483.4
kelch repeat and BTB domain containing 7
chr2_+_219572304 0.76 ENST00000243786.3
inhibin subunit alpha
chr2_+_134838610 0.76 ENST00000356140.10
ENST00000392928.5
aminocarboxymuconate semialdehyde decarboxylase
chr18_+_9885964 0.76 ENST00000357775.6
ENST00000306084.6
thioredoxin domain containing 2
chr15_+_86079863 0.75 ENST00000614907.3
ENST00000441037.7
ATP/GTP binding protein like 1
chr11_-_46826842 0.75 ENST00000526496.1
cytoskeleton associated protein 5
chr5_-_177496802 0.74 ENST00000506161.5
PDZ and LIM domain 7
chr4_+_107825126 0.74 ENST00000503862.5
sphingomyelin synthase 2
chr10_+_66926028 0.74 ENST00000361320.5
leucine rich repeat transmembrane neuronal 3
chr16_+_56747901 0.74 ENST00000568656.5
nucleoporin 93
chr6_-_158818225 0.74 ENST00000337147.11
ezrin
chr2_-_152098810 0.70 ENST00000636442.1
ENST00000638005.1
calcium voltage-gated channel auxiliary subunit beta 4
chr20_-_17558811 0.69 ENST00000536626.7
ENST00000377868.6
beaded filament structural protein 1
chr4_+_107824555 0.69 ENST00000394684.8
sphingomyelin synthase 2
chr11_+_10456186 0.69 ENST00000528723.5
adenosine monophosphate deaminase 3
chr16_+_56748206 0.68 ENST00000566678.1
nucleoporin 93
chr16_+_89921851 0.68 ENST00000554444.5
ENST00000556565.5
tubulin beta 3 class III
chr12_+_28452493 0.67 ENST00000542801.5
coiled-coil domain containing 91
chr6_+_155216637 0.66 ENST00000275246.11
TIAM Rac1 associated GEF 2
chr17_-_29176752 0.65 ENST00000533112.5
myosin XVIIIA
chr17_+_32444379 0.65 ENST00000578213.5
ENST00000649012.1
ENST00000457654.6
ENST00000579451.1
ENST00000261712.8
proteasome 26S subunit, non-ATPase 11
chr6_-_24877262 0.65 ENST00000378023.8
ENST00000540914.5
RHO family interacting cell polarization regulator 2
chr16_+_30664334 0.65 ENST00000287468.5
fibrosin
chr1_+_203026481 0.65 ENST00000367240.6
PTPRF interacting protein alpha 4
chr3_-_132037800 0.64 ENST00000617767.4
copine 4
chr17_+_29929894 0.64 ENST00000536908.6
EF-hand calcium binding domain 5
chr3_+_113747022 0.63 ENST00000273398.8
ENST00000496747.5
ENST00000475322.1
ATPase H+ transporting V1 subunit A
chr4_+_119135825 0.63 ENST00000307128.6
myozenin 2
chr3_+_108589667 0.63 ENST00000361582.8
ENST00000486815.5
DAZ interacting zinc finger protein 3
chr1_+_152908538 0.62 ENST00000368764.4
involucrin
chr1_-_153057504 0.62 ENST00000392653.3
small proline rich protein 2A
chr3_+_108589998 0.61 ENST00000479138.5
DAZ interacting zinc finger protein 3
chr14_-_94388589 0.61 ENST00000402629.1
ENST00000556091.1
ENST00000393087.9
ENST00000554720.1
serpin family A member 1
chr11_-_65662780 0.61 ENST00000534283.1
ENST00000527749.5
ENST00000533187.5
ENST00000525693.5
ENST00000534558.5
ENST00000532879.5
ENST00000406246.8
ENST00000532999.5
RELA proto-oncogene, NF-kB subunit
chr6_-_35921128 0.61 ENST00000510290.5
ENST00000423325.6
SRSF protein kinase 1
chr9_+_34992849 0.61 ENST00000443266.2
DnaJ heat shock protein family (Hsp40) member B5
chr2_-_96844012 0.60 ENST00000318357.9
ENST00000331001.2
ankyrin repeat domain 23
chr11_-_707063 0.60 ENST00000683307.1
DEAF1 transcription factor
chr14_+_103334803 0.60 ENST00000561325.5
ENST00000392715.6
ENST00000559130.5
ENST00000559532.5
ENST00000558506.1
eukaryotic translation initiation factor 5
chr11_-_95232514 0.60 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
sestrin 3
chr14_-_23155302 0.60 ENST00000529705.6
solute carrier family 7 member 8
chr3_+_184817206 0.58 ENST00000441141.5
ENST00000445089.5
VPS8 subunit of CORVET complex
chr5_-_177496845 0.58 ENST00000506537.1
PDZ and LIM domain 7
chr1_+_17308194 0.58 ENST00000375453.5
ENST00000375448.4
peptidyl arginine deiminase 4
chr11_-_123885627 0.57 ENST00000528595.1
ENST00000375026.7
transmembrane protein 225
chr5_+_145937793 0.57 ENST00000511217.1
SH3 domain containing ring finger 2
chr19_-_18884219 0.57 ENST00000596048.1
ceramide synthase 1
chr1_+_44118813 0.56 ENST00000372299.4
Kruppel like factor 17
chr6_-_83709019 0.56 ENST00000519779.5
ENST00000369694.6
ENST00000195649.10
synaptosome associated protein 91
chr7_-_103344588 0.56 ENST00000426036.6
ENST00000249270.11
ENST00000379263.8
ENST00000454277.5
ENST00000412522.1
DnaJ heat shock protein family (Hsp40) member C2
chr2_-_96843992 0.55 ENST00000418232.5
ankyrin repeat domain 23
chr11_-_72070050 0.55 ENST00000535087.5
ENST00000535838.5
nuclear mitotic apparatus protein 1
chr19_-_35513641 0.55 ENST00000339686.8
ENST00000447113.6
dermokine
chr1_+_203127678 0.55 ENST00000640524.1
ENST00000337894.9
adenosine A1 receptor
chr17_-_29140400 0.55 ENST00000528564.2
myosin XVIIIA
chr6_+_155216959 0.55 ENST00000462408.2
TIAM Rac1 associated GEF 2
chr10_-_60140515 0.54 ENST00000486349.2
ankyrin 3
chr4_+_169660062 0.54 ENST00000507875.5
ENST00000613795.4
chloride voltage-gated channel 3
chr8_-_27258386 0.54 ENST00000350889.8
ENST00000519997.5
ENST00000519614.5
ENST00000522908.1
ENST00000265770.11
stathmin 4
chr10_-_73663799 0.54 ENST00000606523.1
synaptopodin 2 like
chr1_-_153094521 0.54 ENST00000368750.8
small proline rich protein 2E
chr3_+_184176949 0.52 ENST00000432591.5
ENST00000431779.5
ENST00000621863.4
adaptor related protein complex 2 subunit mu 1
chr1_-_85404494 0.52 ENST00000633113.1
dimethylarginine dimethylaminohydrolase 1
chr6_-_83709141 0.52 ENST00000521743.5
synaptosome associated protein 91
chr10_-_25062279 0.51 ENST00000615958.4
enkurin, TRPC channel interacting protein
chr3_-_132037714 0.51 ENST00000505957.1
copine 4
chr4_-_99435134 0.51 ENST00000476959.5
ENST00000482593.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_-_207051202 0.50 ENST00000315927.9
YOD1 deubiquitinase
chr9_+_129140004 0.50 ENST00000436883.5
ENST00000414510.5
protein phosphatase 2 phosphatase activator
chr17_+_77450737 0.50 ENST00000541152.6
ENST00000591704.5
septin 9
chrX_+_134237047 0.50 ENST00000370809.4
ENST00000517294.5
coiled-coil domain containing 160
chr5_-_79514127 0.50 ENST00000334082.11
homer scaffold protein 1
chr18_-_43115625 0.49 ENST00000590910.1
ENST00000326695.10
ENST00000589109.5
Ras like without CAAX 2
chr2_-_151971750 0.48 ENST00000636598.1
calcium voltage-gated channel auxiliary subunit beta 4
chr6_-_35921079 0.48 ENST00000507909.1
ENST00000373825.7
SRSF protein kinase 1
chr22_-_19881369 0.48 ENST00000462330.5
thioredoxin reductase 2
chr2_-_96260575 0.48 ENST00000435268.1
transmembrane protein 127
chr22_-_19881163 0.48 ENST00000485358.5
thioredoxin reductase 2
chr5_+_145936554 0.48 ENST00000359120.9
SH3 domain containing ring finger 2
chr19_+_38899680 0.48 ENST00000576510.5
ENST00000392079.7
NFKB inhibitor beta
chr22_+_41976933 0.47 ENST00000396425.7
septin 3
chr9_+_129140067 0.47 ENST00000432124.5
ENST00000435305.1
protein phosphatase 2 phosphatase activator
chr8_-_30727777 0.47 ENST00000537535.5
ENST00000541648.5
ENST00000546342.5
ENST00000221130.11
glutathione-disulfide reductase
chr11_+_394145 0.46 ENST00000528036.5
plakophilin 3
chr12_-_94616061 0.46 ENST00000551457.1
transmembrane and coiled-coil domain family 3
chr17_+_77450547 0.46 ENST00000588958.6
ENST00000586128.5
septin 9
chr12_-_94616371 0.46 ENST00000548918.1
transmembrane and coiled-coil domain family 3
chr16_+_57628226 0.46 ENST00000562414.5
ENST00000561969.5
ENST00000563445.5
ENST00000565338.5
ENST00000567702.5
adhesion G protein-coupled receptor G1
chr4_+_56216101 0.46 ENST00000504228.6
capping protein inhibiting regulator of actin dynamics
chr12_+_57455266 0.46 ENST00000266646.3
inhibin subunit beta E
chr1_-_107688492 0.46 ENST00000415432.6
vav guanine nucleotide exchange factor 3
chr3_+_35643621 0.45 ENST00000419330.5
cAMP regulated phosphoprotein 21
chr11_+_67375985 0.45 ENST00000621995.1
RAD9 checkpoint clamp component A
chr8_-_109975757 0.44 ENST00000524391.6
potassium voltage-gated channel modifier subfamily V member 1
chr6_-_35921047 0.44 ENST00000361690.7
ENST00000512445.5
SRSF protein kinase 1
chr17_+_37491464 0.44 ENST00000613659.1
dual specificity phosphatase 14
chr7_-_135728177 0.44 ENST00000682651.1
ENST00000354042.8
solute carrier family 13 member 4
chr20_+_49812697 0.44 ENST00000417961.5
solute carrier family 9 member A8
chr19_-_48511793 0.44 ENST00000600059.6
lemur tyrosine kinase 3
chr17_-_74868616 0.44 ENST00000579893.1
ENST00000544854.5
ferredoxin reductase
chr2_-_237590694 0.43 ENST00000264601.8
ENST00000411462.5
ENST00000409822.1
RAB17, member RAS oncogene family
chr14_+_103334339 0.43 ENST00000558316.5
ENST00000558265.5
eukaryotic translation initiation factor 5
chr16_+_57628684 0.43 ENST00000567397.5
ENST00000568979.5
ENST00000672974.1
adhesion G protein-coupled receptor G1
chr1_-_150971935 0.43 ENST00000368949.8
ceramide synthase 2
chr12_-_95116967 0.43 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr8_-_42768602 0.43 ENST00000534622.5
cholinergic receptor nicotinic alpha 6 subunit
chr14_+_31025634 0.42 ENST00000673317.1
ENST00000556232.6
ENST00000542754.7
ENST00000554345.6
ENST00000334725.8
ENST00000554609.6
ENST00000313566.11
adaptor related protein complex 4 subunit sigma 1
chr5_+_54455661 0.42 ENST00000302005.3
heat shock protein family B (small) member 3
chr3_-_98522754 0.42 ENST00000513287.5
ENST00000514537.5
ENST00000508071.1
ENST00000507944.5
claudin domain containing 1
chr19_+_46601296 0.42 ENST00000598871.5
ENST00000291295.14
ENST00000594523.5
calmodulin 3
chr15_+_75043263 0.42 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr17_-_61591192 0.41 ENST00000521764.3
nascent polypeptide associated complex subunit alpha 2
chr3_-_18424533 0.41 ENST00000417717.6
SATB homeobox 1
chr5_+_143812161 0.41 ENST00000289448.4
histocompatibility minor HB-1
chr6_+_63571702 0.41 ENST00000672924.1
protein tyrosine phosphatase 4A1
chr18_-_268019 0.40 ENST00000631280.2
ENST00000616322.4
ENST00000261600.11
THO complex 1
chr21_+_18244828 0.40 ENST00000299295.7
chondrolectin
chr17_+_21288029 0.40 ENST00000526076.6
ENST00000361818.9
ENST00000316920.10
mitogen-activated protein kinase kinase 3
chr20_+_49812818 0.40 ENST00000361573.3
solute carrier family 9 member A8
chr11_-_11353241 0.40 ENST00000528848.3
casein kinase 2 alpha 3
chr13_+_75760659 0.40 ENST00000526202.5
ENST00000465261.6
LIM domain 7
chr13_+_75760362 0.39 ENST00000534657.5
LIM domain 7
chr2_-_218993401 0.39 ENST00000453769.1
ENST00000392096.6
ENST00000295728.7
crystallin beta A2
chr1_-_153113507 0.39 ENST00000468739.2
small proline rich protein 2F
chr5_-_88731827 0.39 ENST00000627170.2
myocyte enhancer factor 2C
chr17_-_7219813 0.39 ENST00000399510.8
ENST00000648172.8
discs large MAGUK scaffold protein 4
chr3_+_184176778 0.39 ENST00000439647.5
adaptor related protein complex 2 subunit mu 1
chr2_+_27014746 0.38 ENST00000648289.1
ENST00000458529.5
ENST00000402218.1
microtubule associated protein RP/EB family member 3
chr2_-_237590660 0.38 ENST00000409576.1
RAB17, member RAS oncogene family
chr13_+_75760431 0.38 ENST00000321797.12
LIM domain 7
chr3_+_105366877 0.38 ENST00000306107.9
activated leukocyte cell adhesion molecule
chr18_+_24113341 0.38 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr1_+_100538131 0.38 ENST00000315033.5
G protein-coupled receptor 88
chr10_+_59177161 0.37 ENST00000373878.3
phytanoyl-CoA 2-hydroxylase interacting protein like
chr17_+_27471999 0.37 ENST00000583370.5
ENST00000509603.6
ENST00000268763.10
ENST00000398988.7
kinase suppressor of ras 1
chr8_-_27258414 0.37 ENST00000523048.5
stathmin 4
chr17_+_77319465 0.36 ENST00000329047.13
septin 9
chr4_+_153222307 0.36 ENST00000675899.1
ENST00000675611.1
ENST00000674872.1
ENST00000676167.1
tripartite motif containing 2
chr4_+_153222402 0.35 ENST00000676335.1
ENST00000675146.1
tripartite motif containing 2
chr17_+_81683963 0.35 ENST00000676462.1
ENST00000679336.1
ENST00000678196.1
ENST00000677243.1
ENST00000677044.1
ENST00000677109.1
ENST00000677484.1
ENST00000678105.1
ENST00000677209.1
ENST00000329138.9
ENST00000677225.1
ENST00000678866.1
ENST00000676729.1
ENST00000572392.2
ENST00000577012.1
hepatocyte growth factor-regulated tyrosine kinase substrate
chr4_+_48483324 0.35 ENST00000273861.5
solute carrier family 10 member 4
chr12_-_70788914 0.35 ENST00000342084.8
protein tyrosine phosphatase receptor type R
chr5_+_43602648 0.35 ENST00000505678.6
ENST00000512422.5
ENST00000264663.9
ENST00000670904.1
ENST00000653251.1
nicotinamide nucleotide transhydrogenase
chr4_-_99435396 0.35 ENST00000209665.8
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr12_-_118190510 0.35 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr19_+_46601237 0.34 ENST00000597743.5
calmodulin 3
chr3_+_31981740 0.34 ENST00000360311.5
zinc finger protein 860
chr11_+_706117 0.33 ENST00000533256.5
ENST00000614442.4
EPS8 like 2
chr10_-_86521737 0.32 ENST00000298767.10
WAPL cohesin release factor
chr4_-_99435336 0.32 ENST00000437033.7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr2_+_190343930 0.32 ENST00000458647.5
inositol polyphosphate-1-phosphatase
chr10_-_60139733 0.32 ENST00000506635.5
ankyrin 3
chr14_+_34993240 0.32 ENST00000677647.1
signal recognition particle 54

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.4 2.0 GO:1903028 positive regulation of opsonization(GO:1903028)
0.4 1.1 GO:1903210 cellular response to nitrite(GO:0071250) response to nitrite(GO:0080033) glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) response to resveratrol(GO:1904638) cellular response to resveratrol(GO:1904639) positive regulation of progesterone biosynthetic process(GO:2000184)
0.3 1.2 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.3 1.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.3 0.8 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.3 0.8 GO:1902688 regulation of NAD metabolic process(GO:1902688)
0.2 1.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 1.0 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.2 0.8 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.2 0.8 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.2 0.6 GO:0072720 response to dithiothreitol(GO:0072720)
0.2 0.6 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.2 0.5 GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.2 1.1 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.9 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 0.6 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.7 GO:1902896 terminal web assembly(GO:1902896)
0.1 1.4 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 1.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.4 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.9 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.5 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.1 2.0 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.6 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.6 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.9 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 1.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.5 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 1.4 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 1.7 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 0.9 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.8 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.4 GO:1905044 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.1 1.3 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 1.0 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.7 GO:0006196 AMP catabolic process(GO:0006196)
0.1 1.0 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.1 0.9 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.5 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 1.0 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.3 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.8 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.2 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.1 0.2 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.1 0.3 GO:0035853 chromosome passenger complex localization to spindle midzone(GO:0035853)
0.1 1.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.8 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.4 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.1 1.5 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.1 0.6 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.3 GO:0015692 lead ion transport(GO:0015692)
0.1 0.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0 0.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.8 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 2.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.7 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 1.0 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.7 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.4 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.0 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.3 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.4 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.7 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.4 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.8 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.6 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.5 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.7 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.3 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 1.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.6 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.4 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.6 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 1.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.0 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 1.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.4 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.4 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.6 GO:0015695 organic cation transport(GO:0015695)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 1.0 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.2 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.3 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 1.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.6 GO:0001662 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.4 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.4 1.1 GO:1990844 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.3 0.8 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 3.0 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.2 0.8 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.2 0.7 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 1.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.2 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 1.0 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.6 GO:0033263 CORVET complex(GO:0033263)
0.1 0.2 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.4 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.3 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.1 0.6 GO:0055028 cortical microtubule(GO:0055028)
0.1 0.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.6 GO:0060171 stereocilium membrane(GO:0060171)
0.1 1.2 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.9 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 1.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.8 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.9 GO:0036020 endolysosome membrane(GO:0036020)
0.0 2.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.8 GO:0042599 lamellar body(GO:0042599)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.4 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.9 GO:0042641 actomyosin(GO:0042641)
0.0 1.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.4 GO:0014704 intercalated disc(GO:0014704)
0.0 0.9 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 1.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 2.4 GO:0001650 fibrillar center(GO:0001650)
0.0 1.4 GO:0005643 nuclear pore(GO:0005643)
0.0 0.9 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.2 1.4 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 1.4 GO:0019862 IgA binding(GO:0019862)
0.2 1.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.2 1.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.8 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.1 0.9 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.5 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 1.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.6 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.9 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.3 GO:0070975 FHA domain binding(GO:0070975)
0.1 0.5 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.3 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.1 0.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.9 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.9 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 1.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.8 GO:0034711 inhibin binding(GO:0034711)
0.1 0.2 GO:0031775 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.1 1.0 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.2 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.1 0.2 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 0.7 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.5 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.5 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.1 1.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 1.0 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 1.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 1.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.2 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.1 0.3 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.6 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.4 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 1.2 GO:0031432 titin binding(GO:0031432)
0.0 0.8 GO:0042301 phosphate ion binding(GO:0042301)
0.0 1.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.0 1.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 2.3 GO:0030507 spectrin binding(GO:0030507)
0.0 1.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.4 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.7 GO:0043531 ADP binding(GO:0043531)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.2 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.7 GO:0016248 channel inhibitor activity(GO:0016248)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 2.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 1.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 0.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.8 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 1.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 1.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.4 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.5 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK