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Illumina Body Map 2 (GSE30611)

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Results for FOSL1

Z-value: 1.95

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Transcription factors associated with FOSL1

Gene Symbol Gene ID Gene Info
ENSG00000175592.9 FOS like 1, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSL1hg38_v1_chr11_-_65900375_659003970.732.6e-06Click!

Activity profile of FOSL1 motif

Sorted Z-values of FOSL1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_81483226 7.70 ENST00000256104.5
fatty acid binding protein 4
chr17_-_41612757 7.30 ENST00000301653.9
ENST00000593067.1
keratin 16
chr7_+_73830988 7.28 ENST00000340958.4
claudin 4
chr10_+_17228806 6.59 ENST00000497849.1
vimentin
chr10_+_17228515 6.55 ENST00000478746.1
vimentin
chr10_+_17228215 6.33 ENST00000544301.7
vimentin
chr1_-_94541636 5.96 ENST00000370207.4
coagulation factor III, tissue factor
chr1_+_183186238 5.96 ENST00000493293.5
ENST00000264144.5
laminin subunit gamma 2
chr12_+_13196718 5.94 ENST00000431267.2
ENST00000542474.5
ENST00000544053.5
ENST00000256951.10
epithelial membrane protein 1
chr1_-_94541746 5.90 ENST00000334047.12
coagulation factor III, tissue factor
chr19_+_38304105 5.65 ENST00000588605.5
ENST00000301246.10
chromosome 19 open reading frame 33
chr11_+_394196 5.50 ENST00000331563.7
ENST00000531857.1
plakophilin 3
chr1_+_156114700 5.27 ENST00000677389.1
ENST00000368300.9
ENST00000368299.7
lamin A/C
chr12_+_13196777 5.23 ENST00000538364.5
ENST00000396301.7
epithelial membrane protein 1
chr2_+_169509693 5.01 ENST00000284669.2
kelch like family member 41
chr17_-_41586887 4.93 ENST00000167586.7
keratin 14
chr12_+_53098846 4.79 ENST00000650247.1
ENST00000549628.1
insulin like growth factor binding protein 6
chr7_+_23246697 4.67 ENST00000381990.6
ENST00000409458.3
ENST00000647578.1
ENST00000258733.9
glycoprotein nmb
chr1_+_26863140 4.55 ENST00000339276.6
stratifin
chr12_-_91179472 4.53 ENST00000550099.5
ENST00000546391.5
decorin
chr16_-_69726506 4.49 ENST00000561500.5
ENST00000320623.10
ENST00000439109.6
ENST00000564043.1
ENST00000379046.6
ENST00000379047.7
NAD(P)H quinone dehydrogenase 1
chr7_+_22727147 4.43 ENST00000426291.5
ENST00000401651.5
ENST00000258743.10
ENST00000407492.5
ENST00000401630.7
ENST00000406575.1
interleukin 6
chr1_+_156114251 4.30 ENST00000361308.9
lamin A/C
chr12_-_91179355 4.27 ENST00000550563.5
ENST00000546370.5
decorin
chr1_-_151992571 4.18 ENST00000368809.1
S100 calcium binding protein A10
chr7_+_80369547 4.05 ENST00000435819.5
CD36 molecule
chr19_-_55545522 3.90 ENST00000592464.1
ENST00000612221.1
SH3 domain binding kinase family member 3
chr12_-_91179517 3.87 ENST00000551354.1
decorin
chr10_-_79949098 3.85 ENST00000372292.8
surfactant protein D
chr7_+_30921430 3.83 ENST00000409899.5
ENST00000409611.1
aquaporin 1 (Colton blood group)
chr13_-_37598750 3.79 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
periostin
chr11_-_62689523 3.62 ENST00000317449.5
LRRN4 C-terminal like
chr17_-_41624541 3.53 ENST00000540235.5
ENST00000311208.13
keratin 17
chr11_-_57311456 3.48 ENST00000530920.1
tankyrase 1 binding protein 1
chr11_-_111913195 3.46 ENST00000531198.5
ENST00000616970.5
ENST00000527899.6
crystallin alpha B
chr17_-_41624803 3.37 ENST00000463128.5
keratin 17
chr16_-_2858154 3.28 ENST00000571228.1
ENST00000161006.8
serine protease 22
chr3_-_9878765 3.23 ENST00000430427.6
ENST00000383817.5
ENST00000679265.1
cell death inducing DFFA like effector c
chrX_-_155334580 3.22 ENST00000369449.7
ENST00000321926.4
chloride intracellular channel 2
chr11_-_111913134 3.21 ENST00000533971.2
ENST00000526180.6
crystallin alpha B
chr11_+_102112445 3.14 ENST00000524575.5
Yes1 associated transcriptional regulator
chr17_-_41518878 3.14 ENST00000254043.8
keratin 15
chr4_+_168832005 3.14 ENST00000393726.7
ENST00000507735.6
palladin, cytoskeletal associated protein
chr20_-_45827297 3.13 ENST00000372555.8
troponin C2, fast skeletal type
chr5_-_150155828 3.10 ENST00000261799.9
platelet derived growth factor receptor beta
chr17_-_41624382 3.10 ENST00000577817.3
keratin 17
chr3_-_39192584 3.09 ENST00000340369.4
ENST00000421646.1
ENST00000396251.1
xin actin binding repeat containing 1
chr17_-_55722857 3.08 ENST00000424486.3
transmembrane protein 100
chr2_+_47369301 3.06 ENST00000263735.9
epithelial cell adhesion molecule
chr4_+_73740541 3.04 ENST00000401931.1
ENST00000307407.8
C-X-C motif chemokine ligand 8
chr10_-_21174187 2.92 ENST00000417816.2
nebulette
chr11_-_65900413 2.92 ENST00000448083.6
ENST00000531493.5
ENST00000532401.1
FOS like 1, AP-1 transcription factor subunit
chr21_-_26843063 2.90 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr5_-_150155627 2.82 ENST00000517488.1
platelet derived growth factor receptor beta
chr1_-_43285559 2.82 ENST00000523677.6
chromosome 1 open reading frame 210
chr1_+_223701582 2.81 ENST00000433674.6
calpain 2
chr21_-_26843012 2.81 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr3_-_149576203 2.79 ENST00000472417.1
WW domain containing transcription regulator 1
chr12_-_55842950 2.77 ENST00000548629.5
matrix metallopeptidase 19
chr13_+_77535742 2.76 ENST00000377246.7
sciellin
chr11_-_111923722 2.74 ENST00000527950.5
crystallin alpha B
chr11_-_6320494 2.74 ENST00000303927.4
ENST00000530979.1
caveolae associated protein 3
chr13_+_77535681 2.73 ENST00000349847.4
sciellin
chr18_+_23873000 2.72 ENST00000269217.11
ENST00000587184.5
laminin subunit alpha 3
chr9_-_127578989 2.71 ENST00000373314.7
niban apoptosis regulator 2
chr12_-_55707865 2.70 ENST00000347027.10
ENST00000257879.11
ENST00000553804.6
integrin subunit alpha 7
chr22_-_36365036 2.68 ENST00000456729.1
ENST00000401701.1
myosin heavy chain 9
chr19_+_6740878 2.67 ENST00000596673.1
thyroid hormone receptor interactor 10
chr5_+_150640678 2.58 ENST00000519664.1
synaptopodin
chr9_-_107489754 2.58 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr13_+_77535669 2.57 ENST00000535157.5
sciellin
chr11_+_35176611 2.57 ENST00000279452.10
CD44 molecule (Indian blood group)
chr2_+_28392802 2.55 ENST00000379619.5
ENST00000264716.9
FOS like 2, AP-1 transcription factor subunit
chr8_+_119208322 2.55 ENST00000614891.5
mal, T cell differentiation protein 2
chr7_-_108003122 2.50 ENST00000393559.2
ENST00000222399.11
ENST00000676777.1
ENST00000439976.6
ENST00000393560.5
ENST00000677793.1
ENST00000679244.1
laminin subunit beta 1
chr10_+_24466487 2.48 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr1_-_112704921 2.48 ENST00000414971.1
ENST00000534717.5
ras homolog family member C
chr1_-_79188467 2.48 ENST00000656300.1
adhesion G protein-coupled receptor L4
chr8_-_107497909 2.47 ENST00000517746.6
angiopoietin 1
chr8_+_119207949 2.43 ENST00000534619.5
mal, T cell differentiation protein 2
chr11_+_35176639 2.39 ENST00000527889.6
CD44 molecule (Indian blood group)
chr3_-_149377637 2.39 ENST00000305366.8
transmembrane 4 L six family member 1
chr11_+_35176696 2.37 ENST00000528455.5
CD44 molecule (Indian blood group)
chr5_+_150640652 2.37 ENST00000307662.5
synaptopodin
chr11_+_35176575 2.33 ENST00000526000.6
CD44 molecule (Indian blood group)
chr21_-_42366525 2.32 ENST00000291527.3
trefoil factor 1
chr13_-_41019289 2.31 ENST00000239882.7
E74 like ETS transcription factor 1
chr6_-_169250825 2.31 ENST00000676869.1
ENST00000676760.1
thrombospondin 2
chr4_+_119135825 2.30 ENST00000307128.6
myozenin 2
chr17_-_28718405 2.29 ENST00000430132.6
ENST00000301043.10
ENST00000412625.5
RAB34, member RAS oncogene family
chr21_-_35049238 2.29 ENST00000416754.1
ENST00000437180.5
ENST00000455571.5
ENST00000675419.1
RUNX family transcription factor 1
chr19_-_35501878 2.29 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
dermokine
chr12_-_55842927 2.29 ENST00000322569.9
ENST00000409200.7
matrix metallopeptidase 19
chr16_+_30065753 2.28 ENST00000642816.3
ENST00000643777.4
ENST00000569798.5
aldolase, fructose-bisphosphate A
chr15_-_34795541 2.27 ENST00000290378.6
actin alpha cardiac muscle 1
chr2_+_27282419 2.25 ENST00000380075.7
ENST00000296098.4
tripartite motif containing 54
chr12_+_10213417 2.23 ENST00000546017.5
ENST00000535576.5
ENST00000539170.5
GABA type A receptor associated protein like 1
chr16_+_30065777 2.22 ENST00000395240.7
ENST00000566846.5
aldolase, fructose-bisphosphate A
chr17_+_21288029 2.22 ENST00000526076.6
ENST00000361818.9
ENST00000316920.10
mitogen-activated protein kinase kinase 3
chr11_-_76669985 2.21 ENST00000407242.6
ENST00000421973.1
leucine rich repeat containing 32
chr11_-_102955705 2.18 ENST00000615555.4
ENST00000340273.4
ENST00000260302.8
matrix metallopeptidase 13
chr19_+_50203607 2.17 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
myosin heavy chain 14
chr10_-_5977492 2.16 ENST00000530685.5
ENST00000397255.7
ENST00000379971.5
ENST00000528354.5
ENST00000397250.6
ENST00000429135.2
interleukin 15 receptor subunit alpha
chr17_-_28718147 2.15 ENST00000436730.7
ENST00000625712.2
ENST00000450529.5
ENST00000583538.5
ENST00000419712.7
ENST00000580843.6
ENST00000582934.1
ENST00000415040.6
ENST00000353676.9
ENST00000453384.7
RAB34, member RAS oncogene family
chr16_-_53052849 2.15 ENST00000619363.2
novel protein
chr10_+_122112957 2.15 ENST00000369001.5
transforming acidic coiled-coil containing protein 2
chr15_+_88639009 2.14 ENST00000306072.10
interferon stimulated exonuclease gene 20
chrX_+_100644183 2.14 ENST00000640889.1
ENST00000373004.5
sushi repeat containing protein X-linked 2
chr12_+_47758958 2.14 ENST00000549243.5
solute carrier family 48 member 1
chr15_+_88638947 2.12 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr17_-_44268119 2.11 ENST00000399246.3
ENST00000262418.12
solute carrier family 4 member 1 (Diego blood group)
chr5_-_141682211 2.09 ENST00000239440.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr1_+_223712491 2.08 ENST00000295006.6
calpain 2
chr18_+_58221535 2.08 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr5_+_102808057 2.05 ENST00000684043.1
ENST00000682407.1
peptidylglycine alpha-amidating monooxygenase
chr1_-_43285606 2.05 ENST00000423420.1
chromosome 1 open reading frame 210
chr11_-_65900375 2.04 ENST00000312562.7
FOS like 1, AP-1 transcription factor subunit
chr19_+_35154715 2.04 ENST00000392218.6
ENST00000543307.5
ENST00000392219.7
ENST00000541435.6
ENST00000590686.5
ENST00000342879.7
ENST00000588699.5
FXYD domain containing ion transport regulator 5
chr2_+_151357583 2.02 ENST00000243347.5
TNF alpha induced protein 6
chr13_+_101489940 2.01 ENST00000376162.7
integrin subunit beta like 1
chr1_+_36156096 2.00 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7 domain containing 1
chr2_+_169069537 1.97 ENST00000428522.5
ENST00000450153.1
ENST00000674881.1
ENST00000421653.5
dehydrogenase/reductase 9
chr5_-_141682192 1.97 ENST00000508305.5
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chrX_-_154490614 1.92 ENST00000369649.8
ENST00000393586.1
ENST00000651600.1
solute carrier family 10 member 3
chr3_+_30606574 1.92 ENST00000295754.10
ENST00000359013.4
transforming growth factor beta receptor 2
chr15_+_51341648 1.91 ENST00000335449.11
ENST00000560215.5
gliomedin
chr1_-_209651291 1.90 ENST00000391911.5
ENST00000415782.1
laminin subunit beta 3
chr1_-_159924529 1.90 ENST00000320307.8
transgelin 2
chr10_-_75109172 1.89 ENST00000372700.7
ENST00000473072.2
ENST00000491677.6
ENST00000372702.7
dual specificity phosphatase 13
chr2_-_65366650 1.89 ENST00000443619.6
sprouty related EVH1 domain containing 2
chr19_-_40425982 1.89 ENST00000357949.5
SERTA domain containing 1
chr19_-_35513641 1.87 ENST00000339686.8
ENST00000447113.6
dermokine
chr3_+_138010143 1.86 ENST00000183605.10
claudin 18
chr6_-_138107412 1.85 ENST00000421351.4
p53 apoptosis effector related to PMP22
chr18_+_63887698 1.85 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr10_-_5978022 1.84 ENST00000525219.6
interleukin 15 receptor subunit alpha
chr1_-_79188390 1.84 ENST00000662530.1
adhesion G protein-coupled receptor L4
chr6_+_73695779 1.84 ENST00000422508.6
ENST00000437994.6
CD109 molecule
chr1_-_153057504 1.84 ENST00000392653.3
small proline rich protein 2A
chr12_+_10212836 1.83 ENST00000421801.6
ENST00000544284.5
GABA type A receptor associated protein like 1
chr12_-_52949818 1.83 ENST00000546897.5
ENST00000552551.5
keratin 8
chr16_+_31355165 1.82 ENST00000562918.5
ENST00000268296.9
integrin subunit alpha X
chr15_-_72228676 1.82 ENST00000561609.5
pyruvate kinase M1/2
chr11_-_102798148 1.81 ENST00000315274.7
matrix metallopeptidase 1
chr10_+_86668501 1.81 ENST00000623056.4
ENST00000263066.11
ENST00000429277.7
ENST00000361373.9
ENST00000372066.8
ENST00000372056.8
ENST00000623007.3
LIM domain binding 3
chr12_+_10212483 1.79 ENST00000545859.5
GABA type A receptor associated protein like 1
chr11_+_46380746 1.79 ENST00000405308.6
midkine
chr1_+_36155573 1.79 ENST00000429533.6
MAP7 domain containing 1
chr22_+_22098683 1.77 ENST00000390283.2
immunoglobulin lambda variable 8-61
chr21_-_35049327 1.77 ENST00000300305.7
RUNX family transcription factor 1
chr2_-_165794190 1.77 ENST00000392701.8
ENST00000422973.1
polypeptide N-acetylgalactosaminyltransferase 3
chr2_+_47369467 1.76 ENST00000419334.1
epithelial cell adhesion molecule
chr11_+_34622053 1.75 ENST00000530286.5
ENST00000533754.5
ETS homologous factor
chr11_-_102843597 1.74 ENST00000299855.10
matrix metallopeptidase 3
chr1_+_223701607 1.74 ENST00000434648.5
calpain 2
chr2_+_36696686 1.74 ENST00000379242.7
ENST00000389975.7
vitrin
chr12_-_47758828 1.73 ENST00000389212.7
ENST00000449771.7
Rap guanine nucleotide exchange factor 3
chr3_-_9878488 1.72 ENST00000443115.1
cell death inducing DFFA like effector c
chr10_-_5977589 1.71 ENST00000620345.4
ENST00000397251.7
ENST00000397248.6
ENST00000622442.4
ENST00000620865.4
interleukin 15 receptor subunit alpha
chr12_+_2959870 1.70 ENST00000397122.6
TEA domain transcription factor 4
chr6_+_137867241 1.70 ENST00000612899.5
ENST00000420009.5
TNF alpha induced protein 3
chr3_+_113211539 1.69 ENST00000682979.1
ENST00000485230.5
BOC cell adhesion associated, oncogene regulated
chr1_-_158686700 1.69 ENST00000643759.2
spectrin alpha, erythrocytic 1
chr11_-_96343170 1.69 ENST00000524717.6
mastermind like transcriptional coactivator 2
chr16_+_1256059 1.69 ENST00000397534.6
ENST00000211076.5
tryptase delta 1
chr19_+_35154914 1.68 ENST00000423817.7
FXYD domain containing ion transport regulator 5
chr12_+_10212867 1.68 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABA type A receptor associated protein like 1
chr17_+_4950147 1.67 ENST00000522301.5
enolase 3
chr1_+_36155930 1.67 ENST00000316156.8
MAP7 domain containing 1
chr6_-_31736504 1.67 ENST00000616760.1
ENST00000375784.7
ENST00000375779.6
chloride intracellular channel 1
chr4_+_70195719 1.65 ENST00000683306.1
odontogenic, ameloblast associated
chr6_-_73520170 1.64 ENST00000678508.1
eukaryotic translation elongation factor 1 alpha 1
chr13_+_53028806 1.64 ENST00000219022.3
olfactomedin 4
chr17_+_76265332 1.63 ENST00000327490.8
ENST00000587913.1
UBA like domain containing 2
chr6_+_150721073 1.62 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chr12_-_52949776 1.62 ENST00000548998.5
keratin 8
chr1_+_156126525 1.61 ENST00000504687.6
ENST00000473598.6
lamin A/C
chr19_+_45469841 1.61 ENST00000592811.5
ENST00000586615.5
FosB proto-oncogene, AP-1 transcription factor subunit
chr17_-_41786688 1.60 ENST00000310706.9
ENST00000393931.8
ENST00000424457.5
ENST00000591690.5
junction plakoglobin
chr19_-_45782479 1.59 ENST00000447742.6
ENST00000354227.9
ENST00000291270.9
ENST00000683086.1
ENST00000343373.10
DM1 protein kinase
chr20_-_35438218 1.59 ENST00000374369.8
growth differentiation factor 5
chr14_-_23155302 1.59 ENST00000529705.6
solute carrier family 7 member 8
chr7_-_42237187 1.58 ENST00000395925.8
GLI family zinc finger 3
chr10_+_119651372 1.58 ENST00000369085.8
BAG cochaperone 3
chr17_-_28717741 1.57 ENST00000395243.7
RAB34, member RAS oncogene family
chr6_-_43629222 1.57 ENST00000307126.10
GTP binding protein 2
chr14_-_22957128 1.54 ENST00000342454.12
ENST00000555986.5
ENST00000554516.5
ENST00000347758.6
ENST00000206474.11
ENST00000555040.5
HAUS augmin like complex subunit 4
chr1_-_161021096 1.53 ENST00000537746.1
ENST00000368026.11
F11 receptor
chr19_-_35528221 1.53 ENST00000588674.5
ENST00000452271.7
ENST00000518157.1
suprabasin
chr7_+_143381286 1.53 ENST00000449630.5
ENST00000322764.10
ENST00000457235.5
zyxin
chr12_-_47820562 1.52 ENST00000433685.5
ENST00000447463.5
ENST00000427332.6
histone deacetylase 7
chr20_+_35172046 1.51 ENST00000216968.5
protein C receptor
chr10_-_5977535 1.50 ENST00000379977.8
interleukin 15 receptor subunit alpha
chr1_-_153549238 1.50 ENST00000368713.8
S100 calcium binding protein A3
chr1_+_27392612 1.49 ENST00000374024.4
G protein-coupled receptor 3
chr11_-_47185840 1.49 ENST00000539589.5
ENST00000528462.5
protein kinase C and casein kinase substrate in neurons 3
chr17_-_9791586 1.49 ENST00000571134.2
dehydrogenase/reductase 7C
chr11_-_62556230 1.49 ENST00000530285.5
AHNAK nucleoprotein
chr16_+_31355215 1.48 ENST00000562522.2
integrin subunit alpha X
chr17_-_28717860 1.48 ENST00000395245.9
RAB34, member RAS oncogene family

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 11.9 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
2.1 12.4 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
2.0 5.9 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
1.3 3.8 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
1.2 3.7 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
1.1 4.4 GO:1990637 response to prolactin(GO:1990637)
1.1 4.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.0 19.5 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.9 2.7 GO:0043465 fermentation(GO:0006113) regulation of fermentation(GO:0043465)
0.9 7.3 GO:0007296 vitellogenesis(GO:0007296)
0.9 8.0 GO:0002159 desmosome assembly(GO:0002159)
0.9 3.5 GO:0035853 chromosome passenger complex localization to spindle midzone(GO:0035853)
0.8 4.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.8 2.5 GO:1901389 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.8 5.0 GO:0098886 modification of dendritic spine(GO:0098886)
0.8 2.5 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.8 3.1 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.8 3.8 GO:1990523 bone regeneration(GO:1990523)
0.7 2.9 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.7 13.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.7 9.7 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.7 3.3 GO:0072675 osteoclast fusion(GO:0072675)
0.7 4.6 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.6 2.6 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.6 3.9 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.6 4.8 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.5 2.7 GO:0032796 uropod organization(GO:0032796)
0.5 8.6 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.5 2.1 GO:0060367 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.5 2.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.5 2.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.5 10.8 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.5 9.4 GO:0051546 keratinocyte migration(GO:0051546)
0.5 4.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.4 1.3 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.4 1.3 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.4 16.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 7.7 GO:0071285 cellular response to lithium ion(GO:0071285)
0.4 9.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.4 1.2 GO:0035425 autocrine signaling(GO:0035425)
0.4 8.8 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.4 2.3 GO:0090131 mesenchyme migration(GO:0090131)
0.4 5.7 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.4 10.7 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.4 7.1 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.3 6.6 GO:0016540 protein autoprocessing(GO:0016540)
0.3 11.2 GO:0032060 bleb assembly(GO:0032060)
0.3 1.4 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.3 4.0 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.3 1.3 GO:0044115 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.3 1.0 GO:0046521 sphingoid catabolic process(GO:0046521)
0.3 5.7 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.3 5.0 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.3 5.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.3 2.5 GO:0046952 ketone body catabolic process(GO:0046952)
0.3 4.0 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3 2.1 GO:0018032 protein amidation(GO:0018032)
0.3 4.4 GO:0001765 membrane raft assembly(GO:0001765)
0.3 3.0 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.3 4.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.3 5.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 1.8 GO:0030421 defecation(GO:0030421)
0.2 2.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.2 0.7 GO:0042946 glucoside transport(GO:0042946)
0.2 1.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.2 1.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.7 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.2 1.2 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.2 0.7 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.2 0.9 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.2 2.8 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.2 3.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.2 5.7 GO:0003334 keratinocyte development(GO:0003334)
0.2 9.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 1.6 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.2 2.0 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 3.2 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.2 1.9 GO:0002934 desmosome organization(GO:0002934)
0.2 1.0 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.2 1.8 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.2 1.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 1.3 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.2 0.6 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.2 0.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 0.9 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.2 3.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.2 1.0 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.2 8.2 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.2 0.8 GO:1902896 terminal web assembly(GO:1902896)
0.2 3.7 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 4.9 GO:0034389 lipid particle organization(GO:0034389)
0.2 1.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 1.7 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.2 1.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.7 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 0.4 GO:0051821 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) development involved in symbiotic interaction(GO:0044111) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.1 1.1 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.7 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 2.1 GO:0015886 heme transport(GO:0015886)
0.1 0.8 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.5 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.4 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 4.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 2.0 GO:0030728 ovulation(GO:0030728)
0.1 0.5 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.3 GO:0046108 uridine metabolic process(GO:0046108)
0.1 2.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.7 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.9 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 2.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.1 2.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 9.0 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 0.3 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.4 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.8 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 1.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.2 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.1 2.5 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.6 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.3 GO:1903347 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.5 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 1.2 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.1 2.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 5.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 3.4 GO:0019430 removal of superoxide radicals(GO:0019430)
0.1 1.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.5 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 0.8 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 2.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 1.4 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 2.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 1.4 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.4 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 0.5 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 2.3 GO:0051412 response to corticosterone(GO:0051412)
0.1 0.4 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 1.4 GO:0035855 megakaryocyte development(GO:0035855)
0.1 2.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 2.0 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 1.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 4.3 GO:0035329 hippo signaling(GO:0035329)
0.1 1.0 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 1.0 GO:0051451 myoblast migration(GO:0051451)
0.1 1.9 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 2.3 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.1 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 3.4 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.3 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 2.1 GO:0042730 fibrinolysis(GO:0042730)
0.1 1.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.4 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.7 GO:0014010 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
0.1 0.3 GO:1903296 glutamate secretion, neurotransmission(GO:0061535) regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.1 1.0 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.1 0.2 GO:0015734 taurine transport(GO:0015734)
0.1 1.6 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1 0.7 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 1.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.9 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.1 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 1.5 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.2 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 3.3 GO:0030239 myofibril assembly(GO:0030239)
0.0 1.0 GO:0044849 estrous cycle(GO:0044849)
0.0 2.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.6 GO:0015695 organic cation transport(GO:0015695)
0.0 1.5 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 3.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.5 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 5.0 GO:0042476 odontogenesis(GO:0042476)
0.0 0.6 GO:0045176 apical protein localization(GO:0045176)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 1.7 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 1.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 3.1 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 1.7 GO:0051693 actin filament capping(GO:0051693)
0.0 1.7 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 3.5 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.6 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.0 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.2 GO:0071486 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 4.4 GO:0051225 spindle assembly(GO:0051225)
0.0 0.4 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.6 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 1.7 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.3 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.4 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.6 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 0.6 GO:0060539 diaphragm development(GO:0060539)
0.0 0.8 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 1.1 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 1.5 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 1.3 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 1.9 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 3.2 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 2.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.5 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.9 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 1.5 GO:0016525 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
0.0 0.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 1.1 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 3.1 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.9 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 4.5 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 1.6 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.4 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.0 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0097444 spine apparatus(GO:0097444)
1.3 3.8 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
1.1 12.4 GO:0005638 lamin filament(GO:0005638)
1.0 12.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.9 13.1 GO:0043256 laminin complex(GO:0043256)
0.8 2.5 GO:1990917 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.8 9.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.7 4.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.7 2.8 GO:1902912 pyruvate kinase complex(GO:1902912)
0.7 4.9 GO:0097513 myosin II filament(GO:0097513)
0.6 1.9 GO:1990617 CHOP-ATF4 complex(GO:1990617)
0.6 3.1 GO:0071149 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.6 9.4 GO:0097512 cardiac myofibril(GO:0097512)
0.5 1.6 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.5 2.3 GO:0042643 actomyosin, actin portion(GO:0042643)
0.4 1.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.4 13.5 GO:0031143 pseudopodium(GO:0031143)
0.3 3.5 GO:0005827 polar microtubule(GO:0005827)
0.3 1.4 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.3 2.1 GO:0044753 amphisome(GO:0044753)
0.3 4.8 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.3 1.0 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.3 4.7 GO:0070652 HAUS complex(GO:0070652)
0.3 13.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 1.3 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.3 17.7 GO:0001533 cornified envelope(GO:0001533)
0.3 3.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 1.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 9.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.2 3.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 0.8 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.2 1.9 GO:0030057 desmosome(GO:0030057)
0.2 1.7 GO:0032437 cuticular plate(GO:0032437)
0.2 3.1 GO:0005861 troponin complex(GO:0005861)
0.2 2.8 GO:0016013 syntrophin complex(GO:0016013)
0.2 8.1 GO:0000421 autophagosome membrane(GO:0000421)
0.2 31.2 GO:0005882 intermediate filament(GO:0005882)
0.1 7.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.9 GO:1990032 parallel fiber(GO:1990032)
0.1 0.7 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 2.5 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 1.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 6.5 GO:0008305 integrin complex(GO:0008305)
0.1 2.8 GO:0042599 lamellar body(GO:0042599)
0.1 9.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 2.1 GO:0005915 zonula adherens(GO:0005915)
0.1 0.9 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 3.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 12.8 GO:0005811 lipid particle(GO:0005811)
0.1 1.0 GO:0030478 actin cap(GO:0030478)
0.1 0.9 GO:0055028 cortical microtubule(GO:0055028)
0.1 2.7 GO:0001891 phagocytic cup(GO:0001891)
0.1 9.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 2.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 8.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 3.9 GO:0002102 podosome(GO:0002102)
0.1 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 2.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.3 GO:0097059 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.1 2.2 GO:0043034 costamere(GO:0043034)
0.1 2.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.1 1.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 7.4 GO:0005604 basement membrane(GO:0005604)
0.1 4.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 2.8 GO:0016592 mediator complex(GO:0016592)
0.0 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 7.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 9.4 GO:0030018 Z disc(GO:0030018)
0.0 2.8 GO:0005771 multivesicular body(GO:0005771)
0.0 1.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 4.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 3.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.8 GO:0015030 Cajal body(GO:0015030)
0.0 0.7 GO:0097470 ribbon synapse(GO:0097470)
0.0 6.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 8.7 GO:0043296 apical junction complex(GO:0043296)
0.0 2.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.9 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 7.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.3 GO:0005902 microvillus(GO:0005902)
0.0 3.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 2.2 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 1.0 GO:0005901 caveola(GO:0005901)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.8 GO:0001726 ruffle(GO:0001726)
0.0 0.2 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 24.4 GO:1990254 keratin filament binding(GO:1990254)
1.5 4.5 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
1.5 5.9 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
1.4 4.3 GO:0008859 exoribonuclease II activity(GO:0008859)
1.3 3.8 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
1.1 4.6 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
1.1 10.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.8 2.5 GO:0002135 CTP binding(GO:0002135)
0.6 1.9 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.6 2.5 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.5 1.6 GO:0005199 structural constituent of cell wall(GO:0005199)
0.5 4.7 GO:0045545 syndecan binding(GO:0045545)
0.4 4.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.4 2.6 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.4 4.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.4 2.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 2.8 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 1.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.4 2.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.4 9.1 GO:0030957 Tat protein binding(GO:0030957)
0.3 4.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 4.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 4.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 0.9 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.3 2.1 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.3 2.3 GO:0051373 FATZ binding(GO:0051373)
0.3 1.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 11.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 5.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 11.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 8.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 0.7 GO:0042947 glucoside transmembrane transporter activity(GO:0042947)
0.2 0.7 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.2 1.4 GO:0050436 microfibril binding(GO:0050436)
0.2 1.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 4.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 9.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 1.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 3.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.3 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 1.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 0.9 GO:1990460 leptin receptor binding(GO:1990460)
0.2 5.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 4.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 2.6 GO:0019956 chemokine binding(GO:0019956)
0.2 1.3 GO:0004359 glutaminase activity(GO:0004359)
0.2 2.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.2 4.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 19.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 1.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 1.6 GO:0036122 BMP binding(GO:0036122)
0.1 2.0 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 3.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.5 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 2.1 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.8 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 4.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 3.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.0 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 4.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.3 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 1.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 1.0 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 1.6 GO:0019534 toxin transporter activity(GO:0019534)
0.1 2.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 7.7 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 18.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 2.8 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.4 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.1 4.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 3.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.8 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 15.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 1.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 2.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 2.1 GO:0043495 protein anchor(GO:0043495)
0.1 6.3 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.4 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 0.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 1.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 2.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.3 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 1.6 GO:0048156 tau protein binding(GO:0048156)
0.1 0.9 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 1.4 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.4 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 0.4 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.9 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.3 GO:1903135 cupric ion binding(GO:1903135)
0.1 3.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 14.2 GO:0008201 heparin binding(GO:0008201)
0.1 0.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 2.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.2 GO:0005368 taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
0.1 0.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.9 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 41.3 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 21.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 3.4 GO:0043621 protein self-association(GO:0043621)
0.0 1.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 2.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.6 GO:0070402 NADPH binding(GO:0070402)
0.0 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 13.5 GO:0003779 actin binding(GO:0003779)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 2.9 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 2.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 1.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 4.6 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 2.6 GO:0003823 antigen binding(GO:0003823)
0.0 2.3 GO:0001047 core promoter binding(GO:0001047)
0.0 1.6 GO:0044325 ion channel binding(GO:0044325)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 13.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.4 31.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 19.3 PID AURORA B PATHWAY Aurora B signaling
0.2 8.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 18.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 6.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 7.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 13.2 PID AP1 PATHWAY AP-1 transcription factor network
0.1 2.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 6.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 2.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.1 PID CD40 PATHWAY CD40/CD40L signaling
0.1 5.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 12.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 4.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 7.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 6.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 6.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 2.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 8.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 20.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 4.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 3.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 3.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID FOXO PATHWAY FoxO family signaling
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 2.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 6.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 12.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.4 17.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 6.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 11.9 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2 3.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 4.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 10.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 10.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 7.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 12.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.2 3.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 5.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 7.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 3.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 13.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 1.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 3.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 5.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 5.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 4.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 3.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 3.3 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 0.7 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 7.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.9 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 4.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 5.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 3.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 4.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 5.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 3.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 4.6 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.0 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 1.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.1 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.8 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 3.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins