ISMARA results: FOSL2

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Illumina Body Map 2 (GSE30611)

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Results for FOSL2_SMARCC1

Z-value: 1.67

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Transcription factors associated with FOSL2_SMARCC1

Gene Symbol	Gene ID	Gene Info
FOSL2 Ensembl NCBI GeneCards UniProt	ENSG00000075426.12	FOS like 2, AP-1 transcription factor subunit
SMARCC1 Ensembl NCBI GeneCards UniProt	ENSG00000173473.11	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOSL2	hg38_v1_chr2_+_28392802_28392866	0.60	2.7e-04	Click!
SMARCC1	hg38_v1_chr3_-_47781837_47781908	0.34	5.4e-02	Click!

Activity profile of FOSL2_SMARCC1 motif

Sorted Z-values of FOSL2_SMARCC1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr7_+_73830988 Show fit	10.14	ENST00000340958.4	CLDN4 Ensembl NCBI GeneCards UniProt Show fit	claudin 4
chr22_+_22697789 Show fit	9.60	ENST00000390306.2	IGLV2-23 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-23
chr22_+_22758698 Show fit	9.21	ENST00000390312.2	IGLV2-14 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-14
chr22_+_22720615 Show fit	8.88	ENST00000390309.2	IGLV3-19 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-19
chr8_-_81483226 Show fit	8.81	ENST00000256104.5	FABP4 Ensembl NCBI GeneCards UniProt Show fit	fatty acid binding protein 4
chr2_+_89862438 Show fit	8.34	ENST00000448155.2	IGKV1D-39 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-39
chr22_+_22822658 Show fit	7.62	ENST00000620395.2	IGLV2-8 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-8
chr2_+_89959979 Show fit	7.22	ENST00000453166.2	IGKV2D-28 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-28
chr18_+_23873000 Show fit	6.94	ENST00000269217.11 ENST00000587184.5	LAMA3 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit alpha 3
chr5_+_150640652 Show fit	6.07	ENST00000307662.5	SYNPO Ensembl NCBI GeneCards UniProt Show fit	synaptopodin
chr22_+_22369601 Show fit	5.78	ENST00000390295.3	IGLV7-46 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 7-46
chr7_+_30921430 Show fit	5.41	ENST00000409899.5 ENST00000409611.1	AQP1 Ensembl NCBI GeneCards UniProt Show fit	aquaporin 1 (Colton blood group)
chr12_+_53098846 Show fit	5.33	ENST00000650247.1 ENST00000549628.1	IGFBP6 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor binding protein 6
chr22_+_22734577 Show fit	5.25	ENST00000390310.3	IGLV2-18 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-18
chr17_-_41612757 Show fit	5.21	ENST00000301653.9 ENST00000593067.1	KRT16 Ensembl NCBI GeneCards UniProt Show fit	keratin 16
chr2_+_90100235 Show fit	5.21	ENST00000492446.1	IGKV1D-16 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-16
chr1_+_156114700 Show fit	4.93	ENST00000677389.1 ENST00000368300.9 ENST00000368299.7	LMNA Ensembl NCBI GeneCards UniProt Show fit	lamin A/C
chr2_+_90159840 Show fit	4.66	ENST00000377032.5	IGKV1D-12 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-12
chr22_+_22431949 Show fit	4.56	ENST00000390301.3	IGLV1-36 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-36
chr2_+_89851723 Show fit	4.54	ENST00000429992.2	IGKV2D-40 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-40
chr22_+_22195753 Show fit	4.50	ENST00000390285.4	IGLV6-57 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 6-57
chr20_-_45827297 Show fit	4.48	ENST00000372555.8	TNNC2 Ensembl NCBI GeneCards UniProt Show fit	troponin C2, fast skeletal type
chr10_+_17228806 Show fit	4.27	ENST00000497849.1	VIM Ensembl NCBI GeneCards UniProt Show fit	vimentin
chr2_+_90082635 Show fit	4.23	ENST00000483379.1	IGKV1D-17 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-17
chr11_+_102112445 Show fit	4.17	ENST00000524575.5	YAP1 Ensembl NCBI GeneCards UniProt Show fit	Yes1 associated transcriptional regulator
chr17_-_42423246 Show fit	4.16	ENST00000357037.6	CAVIN1 Ensembl NCBI GeneCards UniProt Show fit	caveolae associated protein 1
chr10_+_17228215 Show fit	4.13	ENST00000544301.7	VIM Ensembl NCBI GeneCards UniProt Show fit	vimentin
chr2_-_89320146 Show fit	4.12	ENST00000498574.1	IGKV1-39 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-39
chr22_+_22668286 Show fit	4.10	ENST00000390304.2	IGLV3-27 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-27
chr22_+_22214765 Show fit	3.94	ENST00000390287.2	IGLV10-54 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 10-54
chr10_+_17228515 Show fit	3.86	ENST00000478746.1	VIM Ensembl NCBI GeneCards UniProt Show fit	vimentin
chr2_-_89100352 Show fit	3.70	ENST00000479981.1	IGKV1-16 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-16
chr1_+_156114251 Show fit	3.65	ENST00000361308.9	LMNA Ensembl NCBI GeneCards UniProt Show fit	lamin A/C
chr11_-_57311456 Show fit	3.56	ENST00000530920.1	TNKS1BP1 Ensembl NCBI GeneCards UniProt Show fit	tankyrase 1 binding protein 1
chr1_+_223701582 Show fit	3.54	ENST00000433674.6	CAPN2 Ensembl NCBI GeneCards UniProt Show fit	calpain 2
chr11_-_6320494 Show fit	3.32	ENST00000303927.4 ENST00000530979.1	CAVIN3 Ensembl NCBI GeneCards UniProt Show fit	caveolae associated protein 3
chr22_+_22098683 Show fit	3.25	ENST00000390283.2	IGLV8-61 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 8-61
chr16_-_30113528 Show fit	3.20	ENST00000406256.8	GDPD3 Ensembl NCBI GeneCards UniProt Show fit	glycerophosphodiester phosphodiesterase domain containing 3
chr12_+_13196718 Show fit	3.17	ENST00000431267.2 ENST00000542474.5 ENST00000544053.5 ENST00000256951.10	EMP1 Ensembl NCBI GeneCards UniProt Show fit	epithelial membrane protein 1
chr14_-_106622837 Show fit	3.16	ENST00000390628.3	IGHV1-58 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-58
chr5_+_150640678 Show fit	3.11	ENST00000519664.1	SYNPO Ensembl NCBI GeneCards UniProt Show fit	synaptopodin
chr22_+_22792485 Show fit	3.11	ENST00000390314.2	IGLV2-11 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-11
chr22_+_22747383 Show fit	3.05	ENST00000390311.3	IGLV3-16 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-16
chr11_-_62689523 Show fit	3.04	ENST00000317449.5	LRRN4CL Ensembl NCBI GeneCards UniProt Show fit	LRRN4 C-terminal like
chr7_+_22727147 Show fit	3.02	ENST00000426291.5 ENST00000401651.5 ENST00000258743.10 ENST00000407492.5 ENST00000401630.7 ENST00000406575.1	IL6 Ensembl NCBI GeneCards UniProt Show fit	interleukin 6
chr1_-_43285559 Show fit	2.96	ENST00000523677.6	C1orf210 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 210
chr1_+_156126525 Show fit	2.94	ENST00000504687.6 ENST00000473598.6	LMNA Ensembl NCBI GeneCards UniProt Show fit	lamin A/C
chr3_+_36380477 Show fit	2.90	ENST00000457375.6 ENST00000273183.8 ENST00000434649.1	STAC Ensembl NCBI GeneCards UniProt Show fit	SH3 and cysteine rich domain
chr12_-_47758828 Show fit	2.89	ENST00000389212.7 ENST00000449771.7	RAPGEF3 Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 3
chr2_+_89947508 Show fit	2.88	ENST00000491977.1	IGKV2D-29 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-29
chr16_-_72620 Show fit	2.87	ENST00000262316.10	RHBDF1 Ensembl NCBI GeneCards UniProt Show fit	rhomboid 5 homolog 1
chr16_-_69726506 Show fit	2.84	ENST00000561500.5 ENST00000320623.10 ENST00000439109.6 ENST00000564043.1 ENST00000379046.6 ENST00000379047.7	NQO1 Ensembl NCBI GeneCards UniProt Show fit	NAD(P)H quinone dehydrogenase 1
chrX_-_155334580 Show fit	2.84	ENST00000369449.7 ENST00000321926.4	CLIC2 Ensembl NCBI GeneCards UniProt Show fit	chloride intracellular channel 2
chr4_+_73740541 Show fit	2.83	ENST00000401931.1 ENST00000307407.8	CXCL8 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 8
chr1_-_153549238 Show fit	2.80	ENST00000368713.8	S100A3 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A3
chr2_-_89160329 Show fit	2.75	ENST00000390256.2	IGKV6-21 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 6-21 (non-functional)
chr20_+_46008900 Show fit	2.74	ENST00000372330.3	MMP9 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 9
chr22_+_22357739 Show fit	2.73	ENST00000390294.2	IGLV1-47 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-47
chr12_+_13196777 Show fit	2.72	ENST00000538364.5 ENST00000396301.7	EMP1 Ensembl NCBI GeneCards UniProt Show fit	epithelial membrane protein 1
chr2_+_89913982 Show fit	2.70	ENST00000390265.2	IGKV1D-33 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-33
chr1_-_153549120 Show fit	2.66	ENST00000368712.1	S100A3 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A3
chr1_+_26863140 Show fit	2.64	ENST00000339276.6	SFN Ensembl NCBI GeneCards UniProt Show fit	stratifin
chr1_+_223701607 Show fit	2.63	ENST00000434648.5	CAPN2 Ensembl NCBI GeneCards UniProt Show fit	calpain 2
chr12_-_91179472 Show fit	2.61	ENST00000550099.5 ENST00000546391.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr2_-_89117844 Show fit	2.55	ENST00000490686.1	IGKV1-17 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-17
chr19_-_43670153 Show fit	2.55	ENST00000601723.5 ENST00000339082.7 ENST00000340093.8	PLAUR Ensembl NCBI GeneCards UniProt Show fit	plasminogen activator, urokinase receptor
chr6_+_44227025 Show fit	2.54	ENST00000371708.1	SLC29A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 29 member 1 (Augustine blood group)
chr10_+_119651372 Show fit	2.54	ENST00000369085.8	BAG3 Ensembl NCBI GeneCards UniProt Show fit	BAG cochaperone 3
chr16_-_1230089 Show fit	2.53	ENST00000612142.1 ENST00000606293.5	TPSB2 Ensembl NCBI GeneCards UniProt Show fit	tryptase beta 2
chr1_-_151992571 Show fit	2.53	ENST00000368809.1	S100A10 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A10
chr11_-_102798148 Show fit	2.51	ENST00000315274.7	MMP1 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 1
chr22_+_22380766 Show fit	2.50	ENST00000390297.3	IGLV1-44 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-44
chr13_+_101489940 Show fit	2.49	ENST00000376162.7	ITGBL1 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta like 1
chr11_-_111923722 Show fit	2.48	ENST00000527950.5	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin alpha B
chr17_-_15263162 Show fit	2.47	ENST00000674673.1 ENST00000675950.1	PMP22 Ensembl NCBI GeneCards UniProt Show fit	peripheral myelin protein 22
chr6_+_41637005 Show fit	2.44	ENST00000419164.6 ENST00000373051.6	MDFI Ensembl NCBI GeneCards UniProt Show fit	MyoD family inhibitor
chr12_-_91179355 Show fit	2.44	ENST00000550563.5 ENST00000546370.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr6_-_31736504 Show fit	2.42	ENST00000616760.1 ENST00000375784.7 ENST00000375779.6	CLIC1 Ensembl NCBI GeneCards UniProt Show fit	chloride intracellular channel 1
chr2_-_89213917 Show fit	2.42	ENST00000498435.1	IGKV1-27 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-27
chr2_+_90021567 Show fit	2.41	ENST00000436451.2	IGKV6D-21 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 6D-21 (non-functional)
chr22_+_22395005 Show fit	2.40	ENST00000390298.2	IGLV7-43 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 7-43
chr1_-_156705575 Show fit	2.38	ENST00000368222.8	CRABP2 Ensembl NCBI GeneCards UniProt Show fit	cellular retinoic acid binding protein 2
chr5_-_150155828 Show fit	2.38	ENST00000261799.9	PDGFRB Ensembl NCBI GeneCards UniProt Show fit	platelet derived growth factor receptor beta
chr3_-_12158901 Show fit	2.35	ENST00000287814.5	TIMP4 Ensembl NCBI GeneCards UniProt Show fit	TIMP metallopeptidase inhibitor 4
chrX_+_100644183 Show fit	2.32	ENST00000640889.1 ENST00000373004.5	SRPX2 Ensembl NCBI GeneCards UniProt Show fit	sushi repeat containing protein X-linked 2
chr1_+_183186238 Show fit	2.30	ENST00000493293.5 ENST00000264144.5	LAMC2 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit gamma 2
chr16_+_1240698 Show fit	2.26	ENST00000561736.2 ENST00000338844.8 ENST00000461509.6	TPSAB1 Ensembl NCBI GeneCards UniProt Show fit	tryptase alpha/beta 1
chr7_+_94394886 Show fit	2.25	ENST00000297268.11 ENST00000620463.1	COL1A2 Ensembl NCBI GeneCards UniProt Show fit	collagen type I alpha 2 chain
chr9_-_107489754 Show fit	2.23	ENST00000610832.1 ENST00000374672.5	KLF4 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 4
chr1_+_156126160 Show fit	2.22	ENST00000448611.6 ENST00000368297.5	LMNA Ensembl NCBI GeneCards UniProt Show fit	lamin A/C
chr2_+_169509693 Show fit	2.20	ENST00000284669.2	KLHL41 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 41
chr19_+_48874318 Show fit	2.19	ENST00000600406.1	PPP1R15A Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 15A
chr3_-_149377637 Show fit	2.19	ENST00000305366.8	TM4SF1 Ensembl NCBI GeneCards UniProt Show fit	transmembrane 4 L six family member 1
chr22_+_22375984 Show fit	2.18	ENST00000390296.2	IGLV5-45 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 5-45
chr2_-_89040745 Show fit	2.16	ENST00000480492.1	IGKV1-12 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-12
chr12_+_47758958 Show fit	2.15	ENST00000549243.5	SLC48A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 48 member 1
chr11_-_111913195 Show fit	2.15	ENST00000531198.5 ENST00000616970.5 ENST00000527899.6	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin alpha B
chr6_-_73520170 Show fit	2.14	ENST00000678508.1	EEF1A1 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 alpha 1
chr10_+_102395693 Show fit	2.13	ENST00000652277.1 ENST00000189444.11 ENST00000661543.1	NFKB2 Ensembl NCBI GeneCards UniProt Show fit	nuclear factor kappa B subunit 2
chr10_-_44385043 Show fit	2.13	ENST00000374426.6 ENST00000395794.2 ENST00000374429.6 ENST00000395793.7 ENST00000343575.10 ENST00000395795.5	CXCL12 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 12
chr1_-_153565535 Show fit	2.12	ENST00000368707.5	S100A2 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A2
chr12_+_2959296 Show fit	2.12	ENST00000358409.7 ENST00000359864.8 ENST00000540314.2 ENST00000536826.2	TEAD4 Ensembl NCBI GeneCards UniProt Show fit	TEA domain transcription factor 4
chr6_+_130366281 Show fit	2.09	ENST00000617887.4	TMEM200A Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 200A
chr9_-_35685462 Show fit	2.08	ENST00000607559.1	TPM2 Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 2
chr4_+_168832005 Show fit	2.07	ENST00000393726.7 ENST00000507735.6	PALLD Ensembl NCBI GeneCards UniProt Show fit	palladin, cytoskeletal associated protein
chr17_-_41586887 Show fit	2.06	ENST00000167586.7	KRT14 Ensembl NCBI GeneCards UniProt Show fit	keratin 14
chr13_-_41019289 Show fit	2.04	ENST00000239882.7	ELF1 Ensembl NCBI GeneCards UniProt Show fit	E74 like ETS transcription factor 1
chr12_+_2959870 Show fit	2.03	ENST00000397122.6	TEAD4 Ensembl NCBI GeneCards UniProt Show fit	TEA domain transcription factor 4
chr11_-_102874974 Show fit	2.03	ENST00000571244.3	MMP12 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 12
chr2_+_47369301 Show fit	2.02	ENST00000263735.9	EPCAM Ensembl NCBI GeneCards UniProt Show fit	epithelial cell adhesion molecule
chr21_-_26843012 Show fit	2.01	ENST00000517777.6	ADAMTS1 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif 1
chr21_-_26843063 Show fit	2.00	ENST00000678221.1	ADAMTS1 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif 1
chr19_-_46625037 Show fit	2.00	ENST00000596260.1 ENST00000594275.1 ENST00000597185.1 ENST00000598865.5 ENST00000291294.7	PTGIR Ensembl NCBI GeneCards UniProt Show fit	prostaglandin I2 receptor
chr11_-_111913134 Show fit	1.97	ENST00000533971.2 ENST00000526180.6	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin alpha B
chr11_+_10305065 Show fit	1.96	ENST00000534464.1 ENST00000278175.10 ENST00000530439.1 ENST00000524948.5 ENST00000528655.5 ENST00000526492.4 ENST00000525063.2	ADM Ensembl NCBI GeneCards UniProt Show fit	adrenomedullin
chr22_+_22030934 Show fit	1.96	ENST00000390282.2	IGLV4-69 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 4-69
chr8_+_103372388 Show fit	1.94	ENST00000520337.1	CTHRC1 Ensembl NCBI GeneCards UniProt Show fit	collagen triple helix repeat containing 1
chr6_-_73520441 Show fit	1.92	ENST00000615060.5	EEF1A1 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 alpha 1
chr8_+_125430333 Show fit	1.92	ENST00000311922.4	TRIB1 Ensembl NCBI GeneCards UniProt Show fit	tribbles pseudokinase 1
chr8_+_86098901 Show fit	1.91	ENST00000285393.4	ATP6V0D2 Ensembl NCBI GeneCards UniProt Show fit	ATPase H+ transporting V0 subunit d2
chr9_-_127578989 Show fit	1.91	ENST00000373314.7	NIBAN2 Ensembl NCBI GeneCards UniProt Show fit	niban apoptosis regulator 2
chr1_+_36156096 Show fit	1.88	ENST00000474796.2 ENST00000373150.8 ENST00000373151.6	MAP7D1 Ensembl NCBI GeneCards UniProt Show fit	MAP7 domain containing 1
chr19_-_35501878 Show fit	1.88	ENST00000593342.5 ENST00000601650.1 ENST00000408915.6	DMKN Ensembl NCBI GeneCards UniProt Show fit	dermokine
chr8_+_69563824 Show fit	1.86	ENST00000525999.5	SULF1 Ensembl NCBI GeneCards UniProt Show fit	sulfatase 1
chr20_+_35172046 Show fit	1.85	ENST00000216968.5	PROCR Ensembl NCBI GeneCards UniProt Show fit	protein C receptor
chr3_+_11137093 Show fit	1.84	ENST00000438284.2	HRH1 Ensembl NCBI GeneCards UniProt Show fit	histamine receptor H1
chr2_+_119431846 Show fit	1.84	ENST00000306406.5	TMEM37 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 37
chr12_-_76084666 Show fit	1.83	ENST00000393263.7 ENST00000548044.5 ENST00000547704.5 ENST00000618691.5 ENST00000431879.7 ENST00000549596.5 ENST00000550934.5 ENST00000551600.5 ENST00000547479.5 ENST00000547773.5 ENST00000544816.5 ENST00000542344.5 ENST00000548273.5	NAP1L1 Ensembl NCBI GeneCards UniProt Show fit	nucleosome assembly protein 1 like 1
chr6_+_73695779 Show fit	1.82	ENST00000422508.6 ENST00000437994.6	CD109 Ensembl NCBI GeneCards UniProt Show fit	CD109 molecule
chrX_+_136169624 Show fit	1.79	ENST00000394153.6	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr12_-_76084612 Show fit	1.79	ENST00000535020.6 ENST00000552342.5	NAP1L1 Ensembl NCBI GeneCards UniProt Show fit	nucleosome assembly protein 1 like 1
chr1_-_43285606 Show fit	1.79	ENST00000423420.1	C1orf210 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 210
chr3_+_30606574 Show fit	1.77	ENST00000295754.10 ENST00000359013.4	TGFBR2 Ensembl NCBI GeneCards UniProt Show fit	transforming growth factor beta receptor 2
chr3_+_191329342 Show fit	1.76	ENST00000392455.9	CCDC50 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 50
chr11_+_394196 Show fit	1.75	ENST00000331563.7 ENST00000531857.1	PKP3 Ensembl NCBI GeneCards UniProt Show fit	plakophilin 3
chr12_-_91179517 Show fit	1.74	ENST00000551354.1	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr11_-_65900413 Show fit	1.74	ENST00000448083.6 ENST00000531493.5 ENST00000532401.1	FOSL1 Ensembl NCBI GeneCards UniProt Show fit	FOS like 1, AP-1 transcription factor subunit
chr12_-_55842950 Show fit	1.73	ENST00000548629.5	MMP19 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 19
chr11_-_111379268 Show fit	1.73	ENST00000393067.8	POU2AF1 Ensembl NCBI GeneCards UniProt Show fit	POU class 2 homeobox associating factor 1
chr12_-_55728994 Show fit	1.73	ENST00000257857.9	CD63 Ensembl NCBI GeneCards UniProt Show fit	CD63 molecule
chr5_-_150155627 Show fit	1.73	ENST00000517488.1	PDGFRB Ensembl NCBI GeneCards UniProt Show fit	platelet derived growth factor receptor beta
chr11_-_10568571 Show fit	1.73	ENST00000529598.1	LYVE1 Ensembl NCBI GeneCards UniProt Show fit	lymphatic vessel endothelial hyaluronan receptor 1
chr11_+_67583742 Show fit	1.72	ENST00000398603.6	GSTP1 Ensembl NCBI GeneCards UniProt Show fit	glutathione S-transferase pi 1
chr1_-_6602859 Show fit	1.72	ENST00000377658.8	KLHL21 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 21
chrX_+_116436599 Show fit	1.72	ENST00000598581.3	SLC6A14 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 14
chr3_-_100114488 Show fit	1.71	ENST00000477258.2 ENST00000354552.7 ENST00000331335.9 ENST00000398326.2	FILIP1L Ensembl NCBI GeneCards UniProt Show fit	filamin A interacting protein 1 like
chr12_-_55707865 Show fit	1.70	ENST00000347027.10 ENST00000257879.11 ENST00000553804.6	ITGA7 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha 7
chrX_-_49043345 Show fit	1.68	ENST00000315869.8	TFE3 Ensembl NCBI GeneCards UniProt Show fit	transcription factor binding to IGHM enhancer 3
chr1_-_6602885 Show fit	1.67	ENST00000377663.3	KLHL21 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 21
chr11_+_67583803 Show fit	1.67	ENST00000398606.10	GSTP1 Ensembl NCBI GeneCards UniProt Show fit	glutathione S-transferase pi 1
chr6_+_130365958 Show fit	1.67	ENST00000296978.4	TMEM200A Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 200A
chr3_+_48466222 Show fit	1.66	ENST00000625293.3 ENST00000492235.2 ENST00000635452.2 ENST00000456089.1	TREX1 Ensembl NCBI GeneCards UniProt Show fit	three prime repair exonuclease 1
chr9_-_127122623 Show fit	1.65	ENST00000373417.1 ENST00000373425.8	ANGPTL2 Ensembl NCBI GeneCards UniProt Show fit	angiopoietin like 2
chr19_-_40425982 Show fit	1.65	ENST00000357949.5	SERTAD1 Ensembl NCBI GeneCards UniProt Show fit	SERTA domain containing 1
chr15_+_40844018 Show fit	1.65	ENST00000344051.8 ENST00000562057.6	SPINT1 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor, Kunitz type 1
chr15_+_88638947 Show fit	1.64	ENST00000559876.2	ISG20 Ensembl NCBI GeneCards UniProt Show fit	interferon stimulated exonuclease gene 20
chr5_-_76623391 Show fit	1.63	ENST00000296641.5 ENST00000504899.1	F2RL2 Ensembl NCBI GeneCards UniProt Show fit	coagulation factor II thrombin receptor like 2
chr11_-_76669985 Show fit	1.63	ENST00000407242.6 ENST00000421973.1	LRRC32 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 32
chr1_-_223665685 Show fit	1.63	ENST00000366872.10	CAPN8 Ensembl NCBI GeneCards UniProt Show fit	calpain 8
chr15_+_67128103 Show fit	1.63	ENST00000558894.5	SMAD3 Ensembl NCBI GeneCards UniProt Show fit	SMAD family member 3
chr17_+_7579491 Show fit	1.62	ENST00000380498.10 ENST00000584502.1 ENST00000250092.11	CD68 Ensembl NCBI GeneCards UniProt Show fit	CD68 molecule
chr3_+_191329020 Show fit	1.61	ENST00000392456.4	CCDC50 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 50
chr19_-_43780957 Show fit	1.60	ENST00000648319.1	KCNN4 Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily N member 4
chr20_+_37383648 Show fit	1.60	ENST00000373567.6	SRC Ensembl NCBI GeneCards UniProt Show fit	SRC proto-oncogene, non-receptor tyrosine kinase
chr12_-_55728977 Show fit	1.58	ENST00000552164.5	CD63 Ensembl NCBI GeneCards UniProt Show fit	CD63 molecule
chrX_+_136169664 Show fit	1.56	ENST00000456445.5	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr5_-_141682192 Show fit	1.54	ENST00000508305.5	ARAP3 Ensembl NCBI GeneCards UniProt Show fit	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr16_-_53052849 Show fit	1.53	ENST00000619363.2	ENSG00000277639.2 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chrX_+_136169833 Show fit	1.52	ENST00000628032.2	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr17_-_1486124 Show fit	1.52	ENST00000575158.5	MYO1C Ensembl NCBI GeneCards UniProt Show fit	myosin IC
chr5_-_141682211 Show fit	1.52	ENST00000239440.9	ARAP3 Ensembl NCBI GeneCards UniProt Show fit	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr12_-_57520480 Show fit	1.52	ENST00000642841.1 ENST00000547303.5 ENST00000552740.5 ENST00000547526.1 ENST00000346473.8 ENST00000551116.5	ENSG00000285133.1 Ensembl NCBI GeneCards UniProt Show fit DDIT3 Ensembl NCBI GeneCards UniProt Show fit	novel protein DNA damage inducible transcript 3
chr7_-_108003122 Show fit	1.48	ENST00000393559.2 ENST00000222399.11 ENST00000676777.1 ENST00000439976.6 ENST00000393560.5 ENST00000677793.1 ENST00000679244.1	LAMB1 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit beta 1
chrX_+_49171918 Show fit	1.48	ENST00000376322.7	PLP2 Ensembl NCBI GeneCards UniProt Show fit	proteolipid protein 2
chr6_+_33075952 Show fit	1.47	ENST00000418931.7	HLA-DPB1 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DP beta 1
chr12_+_2959791 Show fit	1.46	ENST00000543035.6	TEAD4 Ensembl NCBI GeneCards UniProt Show fit	TEA domain transcription factor 4
chrX_+_136169891 Show fit	1.46	ENST00000449474.5	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr11_-_10568650 Show fit	1.46	ENST00000256178.8	LYVE1 Ensembl NCBI GeneCards UniProt Show fit	lymphatic vessel endothelial hyaluronan receptor 1
chr15_-_21742799 Show fit	1.45	ENST00000622410.2	ENSG00000278263.2 Ensembl NCBI GeneCards UniProt Show fit	novel protein, identical to IGHV4-4
chr1_-_12616762 Show fit	1.43	ENST00000464917.5	DHRS3 Ensembl NCBI GeneCards UniProt Show fit	dehydrogenase/reductase 3
chr6_+_73696145 Show fit	1.42	ENST00000287097.6	CD109 Ensembl NCBI GeneCards UniProt Show fit	CD109 molecule
chr17_-_18258556 Show fit	1.41	ENST00000579294.5 ENST00000628188.1 ENST00000545457.6 ENST00000578558.5 ENST00000327031.9	FLII Ensembl NCBI GeneCards UniProt Show fit	FLII actin remodeling protein
chrX_+_49171889 Show fit	1.41	ENST00000376327.6	PLP2 Ensembl NCBI GeneCards UniProt Show fit	proteolipid protein 2
chr11_-_75490725 Show fit	1.41	ENST00000529721.5	GDPD5 Ensembl NCBI GeneCards UniProt Show fit	glycerophosphodiester phosphodiesterase domain containing 5
chr2_+_47369467 Show fit	1.41	ENST00000419334.1	EPCAM Ensembl NCBI GeneCards UniProt Show fit	epithelial cell adhesion molecule
chr10_+_24466487 Show fit	1.40	ENST00000396446.5 ENST00000396445.5 ENST00000376451.4	KIAA1217 Ensembl NCBI GeneCards UniProt Show fit	KIAA1217
chr19_+_38304105 Show fit	1.39	ENST00000588605.5 ENST00000301246.10	C19orf33 Ensembl NCBI GeneCards UniProt Show fit	chromosome 19 open reading frame 33
chr5_-_141651376 Show fit	1.39	ENST00000522783.5 ENST00000519800.1 ENST00000435817.7	FCHSD1 Ensembl NCBI GeneCards UniProt Show fit	FCH and double SH3 domains 1
chr5_-_177497561 Show fit	1.39	ENST00000359895.6 ENST00000355572.6 ENST00000393551.5 ENST00000505074.5 ENST00000393546.8 ENST00000355841.7	PDLIM7 Ensembl NCBI GeneCards UniProt Show fit	PDZ and LIM domain 7
chr17_-_1485733 Show fit	1.38	ENST00000648446.1	MYO1C Ensembl NCBI GeneCards UniProt Show fit	myosin IC
chr16_+_1256059 Show fit	1.37	ENST00000397534.6 ENST00000211076.5	TPSD1 Ensembl NCBI GeneCards UniProt Show fit	tryptase delta 1
chr2_+_102104563 Show fit	1.36	ENST00000409589.5 ENST00000409329.5	IL1R1 Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor type 1
chr2_-_89297785 Show fit	1.36	ENST00000465170.1	IGKV1-37 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-37 (non-functional)
chr11_-_67374168 Show fit	1.36	ENST00000533438.1	CLCF1 Ensembl NCBI GeneCards UniProt Show fit	cardiotrophin like cytokine factor 1
chr19_+_13731744 Show fit	1.35	ENST00000586600.5	CCDC130 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 130
chr2_+_36696686 Show fit	1.35	ENST00000379242.7 ENST00000389975.7	VIT Ensembl NCBI GeneCards UniProt Show fit	vitrin
chr19_-_43781249 Show fit	1.34	ENST00000615047.4	KCNN4 Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily N member 4
chr5_-_135578983 Show fit	1.34	ENST00000512158.6	CXCL14 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 14
chr20_+_44715360 Show fit	1.34	ENST00000190983.5	CCN5 Ensembl NCBI GeneCards UniProt Show fit	cellular communication network factor 5
chr22_+_22771791 Show fit	1.34	ENST00000390313.3	IGLV3-12 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-12

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL2_SMARCC1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	13.7	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
1.8	5.4	GO:0035378	carbon dioxide transmembrane transport(GO:0035378)
1.5	8.9	GO:0098886	modification of dendritic spine(GO:0098886)
1.4	4.1	GO:0060981	cell migration involved in coronary angiogenesis(GO:0060981)
1.1	3.4	GO:0035732	nitric oxide storage(GO:0035732)
1.1	3.3	GO:0043465	fermentation(GO:0006113) regulation of fermentation(GO:0043465)
1.0	3.9	GO:0035853	chromosome passenger complex localization to spindle midzone(GO:0035853)
0.9	4.5	GO:0072675	osteoclast fusion(GO:0072675)
0.8	3.0	GO:1990637	response to prolactin(GO:1990637)
0.7	3.0	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.7	2.9	GO:0006117	acetaldehyde metabolic process(GO:0006117)
0.7	3.3	GO:0014740	negative regulation of muscle hyperplasia(GO:0014740)
0.6	12.3	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.6	1.9	GO:0045645	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.6	98.9	GO:0030449	regulation of complement activation(GO:0030449)
0.6	1.8	GO:2000563	bronchus morphogenesis(GO:0060434) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.6	1.8	GO:1901388	regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.5	2.2	GO:1902310	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496) regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.5	2.1	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.5	2.1	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
0.5	8.8	GO:0071285	cellular response to lithium ion(GO:0071285)
0.5	2.4	GO:1903575	cornified envelope assembly(GO:1903575)
0.5	1.4	GO:1902905	positive regulation of fibril organization(GO:1902905)
0.5	3.6	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.4	1.3	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.4	2.5	GO:0015862	uridine transport(GO:0015862)
0.4	1.2	GO:0060720	spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.4	5.3	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.4	2.8	GO:1904995	negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.4	7.1	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.4	7.0	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.4	2.6	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.4	12.4	GO:0061436	establishment of skin barrier(GO:0061436)
0.4	1.1	GO:1903465	vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.4	1.1	GO:2000452	CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.4	13.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.3	2.8	GO:0007296	vitellogenesis(GO:0007296)
0.3	3.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.3	2.3	GO:0033625	positive regulation of integrin activation(GO:0033625)
0.3	1.3	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.3	2.9	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.3	1.0	GO:0035425	autocrine signaling(GO:0035425)
0.3	2.9	GO:0002159	desmosome assembly(GO:0002159)
0.3	4.7	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.3	1.9	GO:0014846	esophagus smooth muscle contraction(GO:0014846)
0.3	6.8	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3	1.8	GO:0097325	melanocyte proliferation(GO:0097325)
0.3	1.5	GO:0071500	cellular response to nitrosative stress(GO:0071500)
0.3	5.9	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.3	5.9	GO:0016540	protein autoprocessing(GO:0016540)
0.3	3.1	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.3	0.9	GO:0036323	vascular endothelial growth factor receptor-1 signaling pathway(GO:0036323)
0.3	6.4	GO:0007021	tubulin complex assembly(GO:0007021)
0.3	1.9	GO:0043932	ossification involved in bone remodeling(GO:0043932)
0.3	1.3	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.3	2.9	GO:0045906	negative regulation of vasoconstriction(GO:0045906) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.3	2.4	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.3	8.4	GO:0032060	bleb assembly(GO:0032060)
0.3	2.8	GO:2000535	regulation of entry of bacterium into host cell(GO:2000535)
0.3	2.1	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.3	3.5	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2	0.7	GO:0070295	renal water absorption(GO:0070295)
0.2	1.2	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.2	0.9	GO:0052360	multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.2	1.4	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.2	49.6	GO:0002377	immunoglobulin production(GO:0002377)
0.2	1.8	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2	3.5	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.2	3.6	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.2	0.6	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.2	0.8	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.2	1.0	GO:2000863	negative regulation of macrophage chemotaxis(GO:0010760) positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.2	0.8	GO:1902463	protein localization to cell leading edge(GO:1902463)
0.2	0.8	GO:0061055	myotome development(GO:0061055)
0.2	1.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.2	0.6	GO:0046521	sphingoid catabolic process(GO:0046521)
0.2	4.6	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2	0.9	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.2	2.0	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.2	0.5	GO:0007518	myoblast fate determination(GO:0007518)
0.2	2.5	GO:0046541	saliva secretion(GO:0046541)
0.2	0.5	GO:0042946	glucoside transport(GO:0042946)
0.2	3.4	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.2	2.2	GO:0043589	skin morphogenesis(GO:0043589)
0.2	0.5	GO:1903422	negative regulation of synaptic vesicle recycling(GO:1903422)
0.2	1.0	GO:0090131	mesenchyme migration(GO:0090131)
0.2	1.9	GO:0033623	regulation of integrin activation(GO:0033623)
0.2	2.6	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.2	2.8	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.2	3.1	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.2	2.6	GO:0001765	membrane raft assembly(GO:0001765)
0.2	1.2	GO:0015793	glycerol transport(GO:0015793)
0.2	3.2	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.2	1.1	GO:0030421	defecation(GO:0030421)
0.1	1.0	GO:0006543	glutamine catabolic process(GO:0006543)
0.1	0.7	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.1	6.1	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1	0.7	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.9	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	2.0	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.1	0.6	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
0.1	2.4	GO:0046449	creatinine metabolic process(GO:0046449)
0.1	1.8	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.1	1.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.1	3.3	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	3.6	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.1	0.8	GO:0042494	detection of bacterial lipoprotein(GO:0042494)
0.1	0.4	GO:0046108	uridine metabolic process(GO:0046108)
0.1	0.4	GO:0098974	postsynaptic actin cytoskeleton organization(GO:0098974)
0.1	2.5	GO:0031272	regulation of pseudopodium assembly(GO:0031272)
0.1	0.8	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1	0.7	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.1	1.0	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.1	0.5	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.1	1.1	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.1	1.0	GO:0051414	response to cortisol(GO:0051414)
0.1	0.4	GO:0006043	glucosamine catabolic process(GO:0006043)
0.1	0.7	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1	0.6	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.1	0.3	GO:0051097	negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.1	0.8	GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1	1.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.1	2.0	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1	0.8	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1	0.7	GO:0060356	leucine import(GO:0060356)
0.1	0.8	GO:0060005	vestibular reflex(GO:0060005)
0.1	1.2	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.1	1.1	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1	0.3	GO:1902173	negative regulation of keratinocyte apoptotic process(GO:1902173)
0.1	1.8	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.6	GO:0032484	Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1	2.0	GO:0003334	keratinocyte development(GO:0003334)
0.1	0.6	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
0.1	5.5	GO:0035329	hippo signaling(GO:0035329)
0.1	0.4	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1	0.4	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
0.1	0.9	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.1	1.7	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1	1.7	GO:0061635	regulation of protein complex stability(GO:0061635)
0.1	3.4	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.1	4.2	GO:0009303	termination of RNA polymerase I transcription(GO:0006363) rRNA transcription(GO:0009303)
0.1	3.6	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.1	0.2	GO:0044111	development involved in symbiotic interaction(GO:0044111)
0.1	2.2	GO:0035855	megakaryocyte development(GO:0035855)
0.1	1.4	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1	0.8	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.1	0.5	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.1	0.8	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.1	0.9	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1	0.5	GO:0006196	AMP catabolic process(GO:0006196)
0.1	0.3	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1	0.4	GO:1900040	membrane to membrane docking(GO:0022614) regulation of interleukin-2 secretion(GO:1900040) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.1	1.2	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	0.8	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	1.9	GO:0035988	chondrocyte proliferation(GO:0035988)
0.1	0.4	GO:0021817	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.1	0.5	GO:1902031	regulation of NADP metabolic process(GO:1902031)
0.1	0.4	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.1	2.5	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.1	5.1	GO:0003009	skeletal muscle contraction(GO:0003009)
0.1	0.4	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1	0.7	GO:0032887	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1	1.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.1	0.5	GO:0002934	desmosome organization(GO:0002934)
0.1	1.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.6	GO:0035897	proteolysis in other organism(GO:0035897)
0.1	0.7	GO:0002051	osteoblast fate commitment(GO:0002051)
0.1	5.7	GO:0003254	regulation of membrane depolarization(GO:0003254)
0.1	1.4	GO:0040034	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1	0.9	GO:1903817	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1	0.2	GO:0042245	RNA repair(GO:0042245)
0.1	1.1	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.1	3.2	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	1.4	GO:0051014	actin filament severing(GO:0051014)
0.1	0.3	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.1	0.1	GO:1904017	cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1	0.7	GO:0051451	myoblast migration(GO:0051451)
0.1	1.3	GO:0044849	estrous cycle(GO:0044849)
0.1	0.5	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1	0.4	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237) positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	0.6	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.1	0.2	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.1	0.4	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.1	0.5	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.1	0.9	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.1	0.7	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.1	0.4	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.1	0.7	GO:1903543	positive regulation of exosomal secretion(GO:1903543)
0.0	1.9	GO:0007035	vacuolar acidification(GO:0007035)
0.0	1.4	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.0	0.5	GO:2000582	regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	1.3	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0	0.4	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:0015734	taurine transport(GO:0015734)
0.0	0.2	GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0	1.0	GO:0050819	negative regulation of coagulation(GO:0050819)
0.0	2.0	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	3.0	GO:0035987	endodermal cell differentiation(GO:0035987)
0.0	0.2	GO:0051106	positive regulation of DNA ligation(GO:0051106)
0.0	1.9	GO:0006298	mismatch repair(GO:0006298)
0.0	0.1	GO:0070904	L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0	0.6	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.2	GO:0000415	negative regulation of histone H3-K36 methylation(GO:0000415)
0.0	1.2	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:1904158	axonemal central apparatus assembly(GO:1904158)
0.0	5.5	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.0	0.7	GO:0071397	cellular response to cholesterol(GO:0071397)
0.0	0.1	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0	3.1	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.9	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.6	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.8	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.2	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.8	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0	1.2	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	1.5	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.9	GO:0051412	response to corticosterone(GO:0051412)
0.0	2.5	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.4	GO:0010524	positive regulation of calcium ion transport into cytosol(GO:0010524)
0.0	0.1	GO:1901374	acetate ester transport(GO:1901374)
0.0	0.4	GO:0006228	UTP biosynthetic process(GO:0006228)
0.0	0.9	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0	0.4	GO:0010579	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0	0.2	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.8	GO:0045332	phospholipid translocation(GO:0045332)
0.0	0.2	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0	0.4	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.1	GO:0015680	intracellular copper ion transport(GO:0015680)
0.0	0.5	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.2	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.9	GO:0042481	regulation of odontogenesis(GO:0042481)
0.0	0.1	GO:0039516	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0	0.5	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	0.3	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
0.0	0.5	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0	0.8	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.0	0.2	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.0	0.3	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0	0.2	GO:0036152	phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0	0.5	GO:0002076	osteoblast development(GO:0002076)
0.0	0.5	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.1	GO:1903831	acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0	0.9	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.5	GO:0045730	respiratory burst(GO:0045730)
0.0	0.3	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.1	GO:0071105	response to interleukin-11(GO:0071105) cellular response to interleukin-11(GO:0071348)
0.0	0.1	GO:0033131	regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.5	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.1	GO:0098758	interleukin-8-mediated signaling pathway(GO:0038112) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0	0.8	GO:0043535	regulation of blood vessel endothelial cell migration(GO:0043535)
0.0	0.5	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	2.1	GO:0042058	regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0	3.0	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.6	GO:0030574	collagen catabolic process(GO:0030574)
0.0	2.2	GO:0051225	spindle assembly(GO:0051225)
0.0	0.3	GO:0051683	establishment of Golgi localization(GO:0051683)
0.0	0.1	GO:0071955	recycling endosome to Golgi transport(GO:0071955)
0.0	0.2	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.2	GO:0043403	skeletal muscle tissue regeneration(GO:0043403)
0.0	0.2	GO:0032329	serine transport(GO:0032329)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.1	GO:0097012	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0	0.1	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.2	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0030728	ovulation(GO:0030728)
0.0	0.6	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.1	9.2	GO:0097444	spine apparatus(GO:0097444)
1.8	5.4	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
1.2	13.7	GO:0005638	lamin filament(GO:0005638)
0.8	3.4	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.8	4.2	GO:0071149	TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.8	7.7	GO:0005610	laminin-5 complex(GO:0005610)
0.8	3.8	GO:0043256	laminin complex(GO:0043256)
0.7	2.2	GO:0005584	collagen type I trimer(GO:0005584)
0.7	2.9	GO:0035525	NF-kappaB p50/p65 complex(GO:0035525)
0.6	1.8	GO:1990917	sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.6	2.9	GO:0045160	myosin I complex(GO:0045160)
0.6	1.7	GO:0044753	amphisome(GO:0044753)
0.5	2.1	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.5	6.8	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.5	1.5	GO:1990622	CHOP-ATF4 complex(GO:1990617) CHOP-ATF3 complex(GO:1990622)
0.4	3.9	GO:0005827	polar microtubule(GO:0005827)
0.4	6.6	GO:0097512	cardiac myofibril(GO:0097512)
0.4	5.3	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.4	16.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.3	1.2	GO:1902912	pyruvate kinase complex(GO:1902912)
0.3	8.3	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.3	3.5	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3	4.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3	1.7	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.3	4.6	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.3	3.6	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.3	1.4	GO:0097059	CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.3	4.5	GO:0005861	troponin complex(GO:0005861)
0.2	1.8	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2	4.4	GO:0071438	invadopodium membrane(GO:0071438)
0.2	0.7	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2	1.0	GO:0042643	actomyosin, actin portion(GO:0042643)
0.2	1.1	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.2	0.9	GO:1990667	PCSK9-AnxA2 complex(GO:1990667)
0.2	0.9	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2	4.5	GO:0097342	ripoptosome(GO:0097342)
0.2	1.1	GO:0001652	granular component(GO:0001652)
0.1	1.7	GO:0070652	HAUS complex(GO:0070652)
0.1	2.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.7	GO:0033565	ESCRT-0 complex(GO:0033565)
0.1	5.7	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	1.4	GO:0097413	Lewy body(GO:0097413)
0.1	3.6	GO:0030014	CCR4-NOT complex(GO:0030014)
0.1	0.4	GO:0035517	PR-DUB complex(GO:0035517)
0.1	1.9	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1	26.4	GO:0072562	blood microparticle(GO:0072562)
0.1	0.3	GO:1905103	integral component of lysosomal membrane(GO:1905103)
0.1	1.9	GO:0090543	Flemming body(GO:0090543)
0.1	1.0	GO:0030478	actin cap(GO:0030478)
0.1	0.5	GO:0036021	endolysosome lumen(GO:0036021)
0.1	0.5	GO:0070435	Shc-EGFR complex(GO:0070435)
0.1	0.4	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.1	2.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	0.8	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	2.7	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1	3.3	GO:0030057	desmosome(GO:0030057)
0.1	1.5	GO:0042613	MHC class II protein complex(GO:0042613)
0.1	0.5	GO:0032010	phagolysosome(GO:0032010)
0.1	14.6	GO:0005882	intermediate filament(GO:0005882)
0.1	9.6	GO:0005811	lipid particle(GO:0005811)
0.1	4.2	GO:0008305	integrin complex(GO:0008305)
0.1	0.4	GO:0097513	myosin II filament(GO:0097513)
0.1	0.8	GO:0005955	calcineurin complex(GO:0005955)
0.1	0.5	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	2.2	GO:0043218	compact myelin(GO:0043218)
0.1	2.2	GO:0031143	pseudopodium(GO:0031143)
0.1	0.7	GO:0055028	cortical microtubule(GO:0055028)
0.1	6.1	GO:1904724	tertiary granule lumen(GO:1904724)
0.1	0.5	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	1.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	1.5	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	5.8	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	1.5	GO:0044232	organelle membrane contact site(GO:0044232)
0.1	3.7	GO:0002102	podosome(GO:0002102)
0.1	0.4	GO:0060171	stereocilium membrane(GO:0060171)
0.1	0.5	GO:0030905	retromer, tubulation complex(GO:0030905)
0.0	0.3	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	6.2	GO:0005901	caveola(GO:0005901)
0.0	0.2	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.0	1.0	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	1.5	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.4	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0	0.7	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	3.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	1.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	1.9	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:1990716	axonemal central apparatus(GO:1990716)
0.0	0.6	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	2.9	GO:0015030	Cajal body(GO:0015030)
0.0	1.7	GO:0032590	dendrite membrane(GO:0032590)
0.0	2.3	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	5.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.2	GO:0046930	pore complex(GO:0046930)
0.0	4.8	GO:0005903	brush border(GO:0005903)
0.0	0.2	GO:0036156	inner dynein arm(GO:0036156)
0.0	1.0	GO:0010369	chromocenter(GO:0010369)
0.0	0.6	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0036398	TCR signalosome(GO:0036398)
0.0	3.9	GO:0005604	basement membrane(GO:0005604)
0.0	2.8	GO:0034707	chloride channel complex(GO:0034707)
0.0	52.0	GO:0005615	extracellular space(GO:0005615)
0.0	1.8	GO:0031594	neuromuscular junction(GO:0031594)
0.0	2.3	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	1.6	GO:0016592	mediator complex(GO:0016592)
0.0	0.7	GO:0031527	filopodium membrane(GO:0031527)
0.0	1.0	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	1.2	GO:0032420	stereocilium(GO:0032420)
0.0	5.7	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	2.3	GO:0030315	T-tubule(GO:0030315)
0.0	0.4	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.2	GO:0031209	SCAR complex(GO:0031209)
0.0	0.6	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	1.4	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	1.2	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	9.2	GO:0005925	focal adhesion(GO:0005925)
0.0	0.2	GO:0072487	MSL complex(GO:0072487)
0.0	0.5	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	0.4	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.2	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.5	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	1.3	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.2	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	1.1	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	54.3	GO:0005576	extracellular region(GO:0005576)
0.0	1.7	GO:0016324	apical plasma membrane(GO:0016324)
0.0	1.4	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	5.8	GO:0005667	transcription factor complex(GO:0005667)
0.0	1.4	GO:0055037	recycling endosome(GO:0055037)
0.0	1.1	GO:0000118	histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	5.4	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
1.8	14.3	GO:1990254	keratin filament binding(GO:1990254)
1.1	3.4	GO:0035730	S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
1.0	4.2	GO:0042134	rRNA primary transcript binding(GO:0042134)
1.0	4.1	GO:0005019	platelet-derived growth factor beta-receptor activity(GO:0005019)
1.0	3.0	GO:0008859	exoribonuclease II activity(GO:0008859)
0.9	2.8	GO:0003955	NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.7	2.6	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.6	1.8	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.6	6.5	GO:0071532	ankyrin repeat binding(GO:0071532)
0.6	1.8	GO:0002135	CTP binding(GO:0002135)
0.6	152.3	GO:0003823	antigen binding(GO:0003823)
0.5	1.4	GO:0047389	glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.5	3.6	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.4	1.3	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.4	2.5	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
0.4	5.3	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.4	2.2	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.4	5.8	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.4	1.1	GO:0005199	structural constituent of cell wall(GO:0005199)
0.3	0.9	GO:1904928	coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.3	3.4	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.3	1.2	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.3	2.3	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.3	1.5	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.3	0.9	GO:0036327	VEGF-A-activated receptor activity(GO:0036326) VEGF-B-activated receptor activity(GO:0036327) placental growth factor-activated receptor activity(GO:0036332)
0.3	1.4	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3	1.9	GO:0042806	fucose binding(GO:0042806)
0.2	10.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2	1.9	GO:0015057	thrombin receptor activity(GO:0015057)
0.2	1.9	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	7.0	GO:0017160	Ral GTPase binding(GO:0017160)
0.2	1.4	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2	1.4	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.2	0.8	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.2	0.5	GO:0042947	glucoside transmembrane transporter activity(GO:0042947)
0.2	1.2	GO:0015254	glycerol channel activity(GO:0015254)
0.2	1.4	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.2	2.5	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.2	1.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.2	0.6	GO:0008665	2'-phosphotransferase activity(GO:0008665)
0.2	7.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.2	1.9	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2	1.7	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.2	2.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.2	6.7	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	1.3	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.1	0.9	GO:0003998	acylphosphatase activity(GO:0003998)
0.1	1.6	GO:0071253	connexin binding(GO:0071253)
0.1	2.9	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	1.9	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.1	0.5	GO:0032427	GBD domain binding(GO:0032427)
0.1	1.6	GO:0004969	histamine receptor activity(GO:0004969)
0.1	2.2	GO:0015232	heme transporter activity(GO:0015232)
0.1	2.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	1.0	GO:0004359	glutaminase activity(GO:0004359)
0.1	1.0	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.1	0.4	GO:0004850	uridine phosphorylase activity(GO:0004850)
0.1	0.4	GO:0098918	structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1	4.3	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	0.4	GO:0004342	glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1	0.6	GO:0004911	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1	0.6	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.1	0.6	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	1.3	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	4.1	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	1.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.1	0.4	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.1	1.9	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	5.1	GO:0019956	chemokine binding(GO:0019956)
0.1	6.9	GO:0005504	fatty acid binding(GO:0005504)
0.1	0.4	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	18.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.5	GO:0052591	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1	0.5	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.1	3.4	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	2.7	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	2.5	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	2.8	GO:0070410	co-SMAD binding(GO:0070410)
0.1	0.5	GO:1990460	leptin receptor binding(GO:1990460)
0.1	0.2	GO:0090541	MIT domain binding(GO:0090541)
0.1	1.4	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	3.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	8.1	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	1.5	GO:0043522	cAMP response element binding protein binding(GO:0008140) leucine zipper domain binding(GO:0043522)
0.1	1.7	GO:0030957	Tat protein binding(GO:0030957)
0.1	1.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	2.5	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.1	3.2	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	0.7	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.6	GO:0008481	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1	0.5	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1	0.5	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	5.3	GO:0005080	protein kinase C binding(GO:0005080)
0.1	2.1	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.9	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	1.5	GO:0016918	retinal binding(GO:0016918)
0.1	1.3	GO:0005522	profilin binding(GO:0005522)
0.1	0.2	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.1	1.0	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1	0.7	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	1.9	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	0.7	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	1.7	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	2.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.4	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.1	0.5	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.5	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.1	GO:0047225	acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0	1.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.5	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.4	GO:0019215	intermediate filament binding(GO:0019215)
0.0	1.1	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.2	GO:0035514	DNA demethylase activity(GO:0035514)
0.0	0.7	GO:0030274	LIM domain binding(GO:0030274)
0.0	1.7	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	1.0	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0	1.9	GO:0008009	chemokine activity(GO:0008009)
0.0	0.1	GO:0005368	taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
0.0	0.1	GO:0070984	SET domain binding(GO:0070984)
0.0	0.9	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	1.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.7	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	1.2	GO:0043495	protein anchor(GO:0043495)
0.0	0.5	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.3	GO:0043199	sulfate binding(GO:0043199)
0.0	1.2	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0015229	L-ascorbate:sodium symporter activity(GO:0008520) nucleobase transmembrane transporter activity(GO:0015205) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0	0.7	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	1.0	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.9	GO:0070402	NADPH binding(GO:0070402)
0.0	0.5	GO:0042731	PH domain binding(GO:0042731)
0.0	0.1	GO:0005277	acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0	1.0	GO:0070330	aromatase activity(GO:0070330)
0.0	0.7	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	1.1	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	2.4	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.8	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.8	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.5	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.7	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	6.6	GO:0044325	ion channel binding(GO:0044325)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.1	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.0	0.4	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	1.5	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.5	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.6	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.6	GO:0051400	BH domain binding(GO:0051400)
0.0	0.3	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	12.6	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	3.2	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	1.8	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.2	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.2	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.0	4.7	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.3	GO:0001163	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.3	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	25.3	GO:0005198	structural molecule activity(GO:0005198)
0.0	0.3	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	5.8	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.6	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.4	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.2	GO:0019863	IgE binding(GO:0019863)
0.0	0.3	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.4	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.4	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0015322	proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0	0.6	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	0.7	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.4	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993)
0.0	0.9	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.4	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.2	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.6	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.7	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	1.6	GO:0031072	heat shock protein binding(GO:0031072)
0.0	3.2	GO:0005539	glycosaminoglycan binding(GO:0005539)
0.0	0.4	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.6	GO:0001671	ATPase activator activity(GO:0001671)
0.0	8.7	GO:0003779	actin binding(GO:0003779)
0.0	0.1	GO:0043273	CTPase activity(GO:0043273)
0.0	0.1	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	0.2	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.4	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	1.8	GO:0008081	phosphoric diester hydrolase activity(GO:0008081)
0.0	0.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.6	GO:0008536	Ran GTPase binding(GO:0008536)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	12.6	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.4	26.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2	27.6	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.2	6.3	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	13.8	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	5.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	3.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	2.0	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	10.5	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	1.8	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	4.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	2.3	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.1	1.6	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	3.2	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.1	3.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.1	3.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	3.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	3.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	6.2	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	6.1	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	2.3	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.1	6.1	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.1	1.6	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	1.3	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	0.9	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	1.9	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	3.2	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.5	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	5.8	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	1.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	3.0	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.9	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.6	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	1.6	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	2.9	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.8	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.3	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	8.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.4	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.8	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	1.8	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.7	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.4	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.2	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.7	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.9	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.4	PID INSULIN PATHWAY	Insulin Pathway
0.0	2.2	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	5.2	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.3	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.6	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.3	7.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.3	11.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3	2.8	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.3	4.8	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.3	6.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	11.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.2	9.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	15.1	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.2	9.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2	5.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	6.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.2	2.0	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	2.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	14.1	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	5.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	1.9	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	2.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	3.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	3.2	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	2.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	1.6	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	1.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	1.7	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	0.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	6.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	2.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	5.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.5	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	1.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	2.9	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	3.0	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	0.9	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	2.5	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	1.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	0.5	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.1	2.8	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	2.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	2.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	1.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.0	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	2.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	4.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	4.0	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	1.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.7	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	1.0	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	3.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.7	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.8	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	1.6	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	2.0	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	4.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.7	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	1.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.6	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.6	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.6	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.6	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	1.8	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	1.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.5	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.4	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins

Results for FOSL2_SMARCC1

Z-value: 1.67

Motif logo

Transcription factors associated with FOSL2_SMARCC1

Activity-expression correlation:

Activity profile of FOSL2_SMARCC1 motif

Sorted Z-values of FOSL2_SMARCC1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL2_SMARCC1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: