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Illumina Body Map 2 (GSE30611)

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Results for FOXA1

Z-value: 1.81

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Transcription factors associated with FOXA1

Gene Symbol Gene ID Gene Info
FOXA1
ENSG00000129514.8 forkhead box A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXA1hg38_v1_chr14_-_37595224_375952810.631.1e-04Click!

Activity profile of FOXA1 motif

Sorted Z-values of FOXA1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_154612635 10.68 ENST00000407946.5
ENST00000405164.5
ENST00000336098.8
ENST00000393846.6
ENST00000404648.7
ENST00000443553.5
FGG
fibrinogen gamma chain
chr17_-_28368012 10.45 ENST00000555059.2
ENSG00000273171.1
novel protein, readthrough between VTN and SEBOX
chr10_-_79560386 9.99 ENST00000372327.9
ENST00000417041.1
ENST00000640627.1
ENST00000372325.7
SFTPA2
surfactant protein A2
chr10_+_79610932 9.43 ENST00000428376.6
ENST00000398636.8
ENST00000419470.6
ENST00000429958.5
SFTPA1
surfactant protein A1
chr11_-_6440980 8.35 ENST00000265983.8
ENST00000615166.1
HPX
hemopexin
chr11_+_62419025 8.05 ENST00000278282.3
SCGB1A1
secretoglobin family 1A member 1
chr1_-_56966133 7.37 ENST00000535057.5
ENST00000543257.5
C8B
complement C8 beta chain
chr14_-_94323324 7.24 ENST00000341584.4
SERPINA6
serpin family A member 6
chr1_-_56966006 6.82 ENST00000371237.9
C8B
complement C8 beta chain
chr17_-_41528293 6.20 ENST00000455635.1
ENST00000361566.7
KRT19
keratin 19
chr5_-_41213505 6.03 ENST00000337836.10
ENST00000433294.1
C6
complement C6
chr3_+_138010143 5.44 ENST00000183605.10
CLDN18
claudin 18
chr4_-_69495897 5.27 ENST00000305107.7
ENST00000639621.1
UGT2B4
UDP glucuronosyltransferase family 2 member B4
chr2_-_21044063 5.14 ENST00000233242.5
APOB
apolipoprotein B
chr11_-_116792386 5.14 ENST00000433069.2
ENST00000542499.5
APOA5
apolipoprotein A5
chr10_-_46046264 5.09 ENST00000581478.5
ENST00000582163.3
MSMB
microseminoprotein beta
chr3_+_137998735 5.07 ENST00000343735.8
CLDN18
claudin 18
chr2_-_68952880 4.91 ENST00000481498.1
ENST00000328895.9
GKN2
gastrokine 2
chr3_+_186613052 4.76 ENST00000411641.7
ENST00000273784.5
AHSG
alpha 2-HS glycoprotein
chr4_-_69495861 4.69 ENST00000512583.5
UGT2B4
UDP glucuronosyltransferase family 2 member B4
chr22_+_20774092 4.68 ENST00000215727.10
SERPIND1
serpin family D member 1
chr3_+_52777580 4.65 ENST00000273283.7
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr14_-_94323389 4.60 ENST00000557225.1
SERPINA6
serpin family A member 6
chr14_-_37595224 4.58 ENST00000250448.5
FOXA1
forkhead box A1
chr12_-_52949818 4.46 ENST00000546897.5
ENST00000552551.5
KRT8
keratin 8
chr10_+_122560639 4.27 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
DMBT1
deleted in malignant brain tumors 1
chr5_-_41213021 4.27 ENST00000417809.1
C6
complement C6
chr19_+_18386150 4.17 ENST00000252809.3
GDF15
growth differentiation factor 15
chr17_-_47957824 4.11 ENST00000300557.3
PRR15L
proline rich 15 like
chr4_+_186227501 4.00 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
KLKB1
kallikrein B1
chr11_-_124752247 3.90 ENST00000326621.10
VSIG2
V-set and immunoglobulin domain containing 2
chr8_+_119067239 3.87 ENST00000332843.3
COLEC10
collectin subfamily member 10
chr7_-_81770039 3.84 ENST00000222390.11
ENST00000453411.6
ENST00000457544.7
ENST00000444829.7
HGF
hepatocyte growth factor
chr20_-_7940444 3.83 ENST00000378789.4
HAO1
hydroxyacid oxidase 1
chr4_+_186266183 3.75 ENST00000403665.7
ENST00000492972.6
ENST00000264692.8
F11
coagulation factor XI
chr10_+_122560751 3.71 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
DMBT1
deleted in malignant brain tumors 1
chr3_+_186996444 3.67 ENST00000676633.1
ST6GAL1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr12_-_52949776 3.59 ENST00000548998.5
KRT8
keratin 8
chr20_+_33007695 3.50 ENST00000170150.4
BPIFB2
BPI fold containing family B member 2
chr3_+_186974957 3.48 ENST00000438590.5
ST6GAL1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr21_-_42315336 3.40 ENST00000398431.2
ENST00000518498.3
TFF3
trefoil factor 3
chr1_-_26913964 3.27 ENST00000254227.4
NR0B2
nuclear receptor subfamily 0 group B member 2
chr2_-_157488829 3.24 ENST00000435117.1
ENST00000439355.5
CYTIP
cytohesin 1 interacting protein
chr12_-_89352395 3.23 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr3_+_52211442 3.23 ENST00000459884.1
ALAS1
5'-aminolevulinate synthase 1
chr12_-_52949849 3.21 ENST00000619952.2
ENST00000546826.5
KRT8
keratin 8
chr11_-_124752187 3.20 ENST00000403470.1
VSIG2
V-set and immunoglobulin domain containing 2
chr3_-_149221811 3.16 ENST00000455472.3
ENST00000264613.11
CP
ceruloplasmin
chr12_-_89352487 3.15 ENST00000548755.1
ENST00000279488.8
DUSP6
dual specificity phosphatase 6
chr13_-_46142834 3.14 ENST00000674665.1
LCP1
lymphocyte cytosolic protein 1
chr17_+_9021501 3.11 ENST00000173229.7
NTN1
netrin 1
chr20_+_33235987 3.07 ENST00000375422.6
ENST00000375413.8
ENST00000354297.9
BPIFA1
BPI fold containing family A member 1
chr8_+_125430333 3.07 ENST00000311922.4
TRIB1
tribbles pseudokinase 1
chr7_+_73828160 2.99 ENST00000431918.1
CLDN4
claudin 4
chr6_+_160702238 2.98 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
PLG
plasminogen
chr6_-_41747390 2.95 ENST00000356667.8
ENST00000373025.7
ENST00000425343.6
PGC
progastricsin
chr10_-_79949098 2.81 ENST00000372292.8
SFTPD
surfactant protein D
chr14_-_36519679 2.80 ENST00000498187.6
NKX2-1
NK2 homeobox 1
chr10_+_122560679 2.78 ENST00000657942.1
DMBT1
deleted in malignant brain tumors 1
chr4_+_54229261 2.64 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
PDGFRA
platelet derived growth factor receptor alpha
chr17_-_50468871 2.60 ENST00000508540.6
ENST00000258969.4
CHAD
chondroadherin
chr13_+_77535681 2.60 ENST00000349847.4
SCEL
sciellin
chr13_+_77535742 2.59 ENST00000377246.7
SCEL
sciellin
chr6_-_46954922 2.58 ENST00000265417.7
ADGRF5
adhesion G protein-coupled receptor F5
chr12_-_120327762 2.58 ENST00000308366.9
ENST00000423423.3
PLA2G1B
phospholipase A2 group IB
chr13_+_77535669 2.57 ENST00000535157.5
SCEL
sciellin
chr9_+_27109135 2.54 ENST00000519097.5
ENST00000615002.4
TEK
TEK receptor tyrosine kinase
chr7_+_80602150 2.52 ENST00000309881.11
CD36
CD36 molecule
chr15_-_55249029 2.51 ENST00000566877.5
RAB27A
RAB27A, member RAS oncogene family
chr7_+_134891400 2.47 ENST00000393118.6
CALD1
caldesmon 1
chr7_-_81770013 2.45 ENST00000465234.2
HGF
hepatocyte growth factor
chr2_-_21043941 2.42 ENST00000399256.4
APOB
apolipoprotein B
chr12_-_91178520 2.42 ENST00000425043.5
ENST00000420120.6
ENST00000441303.6
ENST00000456569.2
DCN
decorin
chr7_+_80602200 2.42 ENST00000534394.5
CD36
CD36 molecule
chrX_-_15384402 2.41 ENST00000297904.4
VEGFD
vascular endothelial growth factor D
chr18_+_3449620 2.38 ENST00000405385.7
TGIF1
TGFB induced factor homeobox 1
chr9_+_27109200 2.38 ENST00000380036.10
TEK
TEK receptor tyrosine kinase
chr1_+_200027702 2.37 ENST00000367362.8
NR5A2
nuclear receptor subfamily 5 group A member 2
chr11_-_10568650 2.35 ENST00000256178.8
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr19_+_18382163 2.28 ENST00000595973.2
GDF15
growth differentiation factor 15
chr13_-_48413105 2.28 ENST00000620633.5
LPAR6
lysophosphatidic acid receptor 6
chr11_-_108593738 2.19 ENST00000525344.5
ENST00000265843.9
EXPH5
exophilin 5
chr3_+_142596385 2.15 ENST00000457734.7
ENST00000483373.5
ENST00000475296.5
ENST00000495744.5
ENST00000476044.5
ENST00000461644.5
ENST00000464320.5
PLS1
plastin 1
chr7_-_81770122 2.15 ENST00000423064.7
HGF
hepatocyte growth factor
chr14_-_69797232 2.12 ENST00000216540.5
SLC10A1
solute carrier family 10 member 1
chr3_+_148730100 2.11 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
AGTR1
angiotensin II receptor type 1
chr1_+_200027605 2.09 ENST00000236914.7
NR5A2
nuclear receptor subfamily 5 group A member 2
chr19_-_48615050 2.06 ENST00000263266.4
FAM83E
family with sequence similarity 83 member E
chr13_-_85799400 2.04 ENST00000647374.2
SLITRK6
SLIT and NTRK like family member 6
chr2_-_88861563 1.98 ENST00000624935.3
ENST00000390241.3
ENSG00000240040.6
IGKJ2
novel transcript
immunoglobulin kappa joining 2
chr8_-_132760548 1.96 ENST00000519187.5
ENST00000523829.5
ENST00000677595.1
ENST00000356838.7
ENST00000377901.8
ENST00000519304.1
TMEM71
transmembrane protein 71
chr7_+_135148041 1.95 ENST00000275767.3
TMEM140
transmembrane protein 140
chr5_+_102865737 1.94 ENST00000509523.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr5_+_136058849 1.90 ENST00000508076.5
TGFBI
transforming growth factor beta induced
chr7_-_81770362 1.88 ENST00000412881.5
HGF
hepatocyte growth factor
chr13_+_75760659 1.86 ENST00000526202.5
ENST00000465261.6
LMO7
LIM domain 7
chr1_-_203351115 1.84 ENST00000354955.5
FMOD
fibromodulin
chr5_+_102865244 1.81 ENST00000511477.5
ENST00000506006.1
ENST00000509832.5
PAM
peptidylglycine alpha-amidating monooxygenase
chr2_+_202073249 1.79 ENST00000498697.3
KIAA2012
KIAA2012
chr4_-_73620391 1.77 ENST00000395777.6
ENST00000307439.10
RASSF6
Ras association domain family member 6
chr7_-_81769971 1.76 ENST00000354224.10
ENST00000643024.1
HGF
hepatocyte growth factor
chr8_+_54559164 1.74 ENST00000636932.1
RP1
RP1 axonemal microtubule associated
chrX_+_136532205 1.74 ENST00000370634.8
VGLL1
vestigial like family member 1
chrX_+_22032301 1.74 ENST00000379374.5
PHEX
phosphate regulating endopeptidase homolog X-linked
chr12_-_71157872 1.63 ENST00000546561.2
TSPAN8
tetraspanin 8
chr2_-_88860913 1.63 ENST00000390239.2
IGKJ4
immunoglobulin kappa joining 4
chr1_-_114757958 1.62 ENST00000525132.1
CSDE1
cold shock domain containing E1
chr14_+_36657560 1.62 ENST00000402703.6
PAX9
paired box 9
chr12_+_103587266 1.60 ENST00000388887.7
STAB2
stabilin 2
chr2_+_87748087 1.60 ENST00000359481.9
PLGLB2
plasminogen like B2
chr13_+_75760431 1.57 ENST00000321797.12
LMO7
LIM domain 7
chr11_+_1157946 1.56 ENST00000621226.2
MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chr1_-_116667668 1.56 ENST00000369486.8
ENST00000369483.5
IGSF3
immunoglobulin superfamily member 3
chr8_-_132760624 1.53 ENST00000522334.5
ENST00000519016.5
TMEM71
transmembrane protein 71
chr11_-_102530738 1.53 ENST00000260227.5
MMP7
matrix metallopeptidase 7
chr6_+_10528326 1.53 ENST00000379597.7
GCNT2
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr19_-_48390847 1.53 ENST00000597017.5
KDELR1
KDEL endoplasmic reticulum protein retention receptor 1
chr2_+_70935864 1.48 ENST00000234396.10
ENST00000454446.6
ATP6V1B1
ATPase H+ transporting V1 subunit B1
chr15_+_96325935 1.42 ENST00000421109.6
NR2F2
nuclear receptor subfamily 2 group F member 2
chr12_+_120978686 1.41 ENST00000541395.5
ENST00000544413.2
HNF1A
HNF1 homeobox A
chr16_-_68000549 1.41 ENST00000575510.5
DPEP2
dipeptidase 2
chr15_+_71096941 1.40 ENST00000355327.7
THSD4
thrombospondin type 1 domain containing 4
chr12_-_102478539 1.38 ENST00000424202.6
IGF1
insulin like growth factor 1
chr2_+_70935919 1.37 ENST00000412314.5
ATP6V1B1
ATPase H+ transporting V1 subunit B1
chr3_-_146161167 1.36 ENST00000360060.7
ENST00000282903.10
PLOD2
procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
chr8_+_94895837 1.33 ENST00000519136.5
NDUFAF6
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr21_-_14658812 1.32 ENST00000647101.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr12_-_71157992 1.30 ENST00000247829.8
TSPAN8
tetraspanin 8
chr1_-_111200633 1.30 ENST00000357640.9
DENND2D
DENN domain containing 2D
chr6_-_89315291 1.29 ENST00000402938.4
GABRR2
gamma-aminobutyric acid type A receptor subunit rho2
chr6_+_36676489 1.27 ENST00000448526.6
CDKN1A
cyclin dependent kinase inhibitor 1A
chr1_-_94925759 1.26 ENST00000415017.1
ENST00000545882.5
CNN3
calponin 3
chr17_-_59151794 1.25 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr2_+_202073282 1.24 ENST00000459709.5
KIAA2012
KIAA2012
chr12_+_120978537 1.21 ENST00000257555.11
ENST00000400024.6
HNF1A
HNF1 homeobox A
chr1_-_177969907 1.20 ENST00000308284.10
SEC16B
SEC16 homolog B, endoplasmic reticulum export factor
chrX_+_22032427 1.19 ENST00000684143.1
PHEX
phosphate regulating endopeptidase homolog X-linked
chr1_+_222928415 1.17 ENST00000284476.7
DISP1
dispatched RND transporter family member 1
chr18_+_68798237 1.17 ENST00000581520.1
CCDC102B
coiled-coil domain containing 102B
chr7_+_114414809 1.15 ENST00000350908.9
FOXP2
forkhead box P2
chr4_-_73620629 1.15 ENST00000342081.7
RASSF6
Ras association domain family member 6
chr10_-_125161056 1.15 ENST00000530884.1
CTBP2
C-terminal binding protein 2
chr18_-_25351140 1.15 ENST00000577461.1
ZNF521
zinc finger protein 521
chr4_-_110198650 1.13 ENST00000394607.7
ELOVL6
ELOVL fatty acid elongase 6
chr7_+_134891566 1.12 ENST00000424922.5
ENST00000495522.1
CALD1
caldesmon 1
chr18_-_54959391 1.10 ENST00000591504.6
CCDC68
coiled-coil domain containing 68
chr19_-_45406327 1.10 ENST00000593226.5
ENST00000418234.6
PPP1R13L
protein phosphatase 1 regulatory subunit 13 like
chr14_+_36657664 1.09 ENST00000555639.2
PAX9
paired box 9
chr18_+_3449413 1.08 ENST00000549253.5
TGIF1
TGFB induced factor homeobox 1
chr14_+_36661852 1.08 ENST00000361487.7
PAX9
paired box 9
chr17_-_40984297 1.07 ENST00000377755.9
KRT40
keratin 40
chr19_-_48614805 1.07 ENST00000593772.1
FAM83E
family with sequence similarity 83 member E
chr4_-_73620500 1.05 ENST00000335049.5
RASSF6
Ras association domain family member 6
chr7_-_81770428 1.05 ENST00000421558.1
HGF
hepatocyte growth factor
chr8_+_94895763 1.05 ENST00000523378.5
NDUFAF6
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr9_-_20622479 1.03 ENST00000380338.9
MLLT3
MLLT3 super elongation complex subunit
chr5_+_138873990 1.02 ENST00000518381.5
CTNNA1
catenin alpha 1
chr11_+_844406 1.02 ENST00000397404.5
TSPAN4
tetraspanin 4
chrX_+_136648138 1.02 ENST00000370629.7
CD40LG
CD40 ligand
chr5_+_171420016 1.00 ENST00000675071.1
ENSG00000288639.1
novel protein
chr10_+_102776237 1.00 ENST00000369889.5
WBP1L
WW domain binding protein 1 like
chr2_+_168901290 1.00 ENST00000429379.2
ENST00000375363.8
ENST00000421979.1
G6PC2
glucose-6-phosphatase catalytic subunit 2
chr2_-_87021844 0.98 ENST00000355705.4
ENST00000409310.6
PLGLB1
plasminogen like B1
chr22_-_17219424 0.98 ENST00000649540.1
ENST00000399837.8
ENST00000543038.1
ADA2
adenosine deaminase 2
chr4_+_67558719 0.96 ENST00000265404.7
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr10_+_101131284 0.96 ENST00000370196.11
ENST00000467928.2
TLX1
T cell leukemia homeobox 1
chr14_+_22829879 0.91 ENST00000355151.9
ENST00000397496.7
ENST00000555345.5
ENST00000432849.7
ENST00000553711.5
ENST00000556465.5
ENST00000397505.2
ENST00000557221.1
ENST00000556840.5
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr10_+_113709261 0.90 ENST00000672138.1
ENST00000452490.3
CASP7
caspase 7
chr6_-_117425905 0.88 ENST00000368507.8
ROS1
ROS proto-oncogene 1, receptor tyrosine kinase
chr15_+_59617933 0.87 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr19_+_38389612 0.87 ENST00000586301.5
SPRED3
sprouty related EVH1 domain containing 3
chr7_-_93226449 0.86 ENST00000394468.7
ENST00000453812.2
HEPACAM2
HEPACAM family member 2
chr3_+_160677152 0.86 ENST00000320767.4
ARL14
ADP ribosylation factor like GTPase 14
chr12_+_10212483 0.86 ENST00000545859.5
GABARAPL1
GABA type A receptor associated protein like 1
chr3_-_45915596 0.85 ENST00000472635.5
ENST00000492333.5
LZTFL1
leucine zipper transcription factor like 1
chr13_+_75760362 0.84 ENST00000534657.5
LMO7
LIM domain 7
chr17_+_74935892 0.83 ENST00000328801.6
OTOP3
otopetrin 3
chr17_-_41315706 0.82 ENST00000334202.5
KRTAP17-1
keratin associated protein 17-1
chr2_-_88860605 0.81 ENST00000390238.2
IGKJ5
immunoglobulin kappa joining 5
chr1_+_34759737 0.80 ENST00000339480.3
GJB4
gap junction protein beta 4
chr17_-_19748355 0.80 ENST00000494157.6
ALDH3A1
aldehyde dehydrogenase 3 family member A1
chr4_-_40514543 0.79 ENST00000513473.5
RBM47
RNA binding motif protein 47
chr3_-_185821092 0.79 ENST00000421047.3
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr2_+_203936755 0.79 ENST00000316386.11
ENST00000435193.1
ICOS
inducible T cell costimulator
chr6_+_106098933 0.78 ENST00000369089.3
PRDM1
PR/SET domain 1
chr1_-_216423396 0.78 ENST00000366942.3
ENST00000674083.1
ENST00000307340.8
USH2A
usherin
chr14_+_104801082 0.77 ENST00000342537.8
ZBTB42
zinc finger and BTB domain containing 42
chr6_-_107824294 0.77 ENST00000369020.8
ENST00000369022.6
SCML4
Scm polycomb group protein like 4
chr21_-_26843012 0.77 ENST00000517777.6
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chrX_-_20218941 0.77 ENST00000457145.6
RPS6KA3
ribosomal protein S6 kinase A3
chr5_+_180494430 0.77 ENST00000393356.7
ENST00000618123.4
CNOT6
CCR4-NOT transcription complex subunit 6
chr14_+_104800573 0.76 ENST00000555360.1
ZBTB42
zinc finger and BTB domain containing 42
chr12_-_52434363 0.76 ENST00000252245.6
KRT75
keratin 75
chr1_-_11047225 0.76 ENST00000400898.3
ENST00000400897.8
MASP2
mannan binding lectin serine peptidase 2
chr3_-_114179052 0.76 ENST00000383673.5
ENST00000295881.9
DRD3
dopamine receptor D3
chr17_-_17582417 0.75 ENST00000395783.5
PEMT
phosphatidylethanolamine N-methyltransferase
chr4_-_185535498 0.75 ENST00000284767.12
ENST00000284771.7
ENST00000284770.10
ENST00000620787.5
ENST00000629667.2
PDLIM3
PDZ and LIM domain 3
chr22_-_17219571 0.74 ENST00000610390.4
ADA2
adenosine deaminase 2
chr14_-_64504570 0.74 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr4_-_140154176 0.74 ENST00000509479.6
MAML3
mastermind like transcriptional coactivator 3

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.3 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
3.3 10.0 GO:0006711 estrogen catabolic process(GO:0006711)
2.7 10.7 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
1.6 8.0 GO:0010193 response to ozone(GO:0010193)
1.5 4.6 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
1.3 2.6 GO:0035565 regulation of pronephros size(GO:0035565)
1.3 5.1 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
1.3 6.4 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
1.2 8.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
1.1 13.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
1.0 3.1 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
1.0 13.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.9 10.5 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.9 2.6 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.8 7.6 GO:0006642 triglyceride mobilization(GO:0006642)
0.8 4.7 GO:0008218 bioluminescence(GO:0008218)
0.8 3.1 GO:1900228 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.7 14.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.7 11.3 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.7 5.2 GO:0009441 glycolate metabolic process(GO:0009441)
0.6 3.9 GO:0018032 protein amidation(GO:0018032)
0.5 4.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.5 4.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.5 1.6 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.5 2.6 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.5 2.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.5 2.6 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.5 3.0 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.5 2.9 GO:1904383 response to sodium phosphate(GO:1904383)
0.4 2.1 GO:1902896 terminal web assembly(GO:1902896)
0.4 9.4 GO:0008228 opsonization(GO:0008228)
0.4 4.9 GO:0070543 response to linoleic acid(GO:0070543)
0.4 10.7 GO:0031639 plasminogen activation(GO:0031639)
0.4 1.2 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.4 1.8 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.4 2.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.4 1.4 GO:0009956 radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.3 3.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 2.6 GO:0043129 surfactant homeostasis(GO:0043129)
0.3 1.6 GO:0010966 regulation of phosphate transport(GO:0010966)
0.3 1.0 GO:1903970 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.3 2.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 2.8 GO:0021759 globus pallidus development(GO:0021759)
0.3 4.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 11.8 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.3 1.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3 2.4 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.3 7.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.3 0.8 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.2 1.7 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.2 0.9 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.2 1.3 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.2 2.0 GO:0060005 vestibular reflex(GO:0060005)
0.2 2.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 1.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 0.8 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.2 0.5 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 6.5 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 1.0 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 3.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.2 0.8 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 4.8 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 6.2 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.1 0.6 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 1.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 3.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.8 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.9 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.5 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 2.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.5 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 8.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 1.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 2.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.3 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.7 GO:0032808 lacrimal gland development(GO:0032808)
0.1 3.2 GO:0006825 copper ion transport(GO:0006825)
0.1 10.0 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 3.8 GO:0042481 regulation of odontogenesis(GO:0042481)
0.1 1.2 GO:0060174 limb bud formation(GO:0060174)
0.1 0.8 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 3.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.3 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.5 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 2.9 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 1.7 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.8 GO:0042048 olfactory behavior(GO:0042048)
0.1 1.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.5 GO:0044849 estrous cycle(GO:0044849)
0.1 1.3 GO:0060347 heart trabecula formation(GO:0060347)
0.1 1.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.5 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.6 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.5 GO:0051023 regulation of immunoglobulin secretion(GO:0051023)
0.0 0.5 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 1.0 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 3.8 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.7 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 2.9 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.2 GO:2000174 pro-T cell differentiation(GO:0002572) regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.6 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.8 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.8 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.4 GO:0008343 adult feeding behavior(GO:0008343)
0.0 3.3 GO:0031100 organ regeneration(GO:0031100)
0.0 0.6 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 10.0 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 1.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 1.3 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 1.0 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 1.9 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0033572 transferrin transport(GO:0033572)
0.0 0.8 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.3 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.0 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.8 GO:0006081 cellular aldehyde metabolic process(GO:0006081)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 24.5 GO:0005579 membrane attack complex(GO:0005579)
1.4 8.4 GO:1990357 terminal web(GO:1990357)
0.9 7.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.8 10.7 GO:0005577 fibrinogen complex(GO:0005577)
0.7 22.2 GO:0042599 lamellar body(GO:0042599)
0.5 10.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.5 2.9 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.4 1.6 GO:0070701 mucus layer(GO:0070701)
0.3 14.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 8.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.3 0.8 GO:0002141 stereocilia ankle link(GO:0002141) USH2 complex(GO:1990696)
0.3 1.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 5.1 GO:0042627 chylomicron(GO:0042627)
0.2 3.4 GO:0030478 actin cap(GO:0030478)
0.2 2.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 2.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 2.3 GO:0097470 ribbon synapse(GO:0097470)
0.2 22.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 2.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 7.8 GO:0001533 cornified envelope(GO:0001533)
0.1 4.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 3.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.5 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 1.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 8.3 GO:0045178 basal part of cell(GO:0045178)
0.1 9.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 7.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 3.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.0 GO:0016600 flotillin complex(GO:0016600)
0.0 0.7 GO:0016013 syntrophin complex(GO:0016013)
0.0 1.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 8.0 GO:0072562 blood microparticle(GO:0072562)
0.0 6.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 7.6 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 3.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 3.1 GO:0005902 microvillus(GO:0005902)
0.0 0.7 GO:1990777 plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 3.9 GO:0043204 perikaryon(GO:0043204)
0.0 31.9 GO:0005615 extracellular space(GO:0005615)
0.0 2.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.7 GO:0005882 intermediate filament(GO:0005882)
0.0 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 3.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:0035375 zymogen binding(GO:0035375)
1.6 12.7 GO:0035473 lipase binding(GO:0035473)
1.3 3.8 GO:0052852 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
1.0 3.0 GO:1904854 proteasome core complex binding(GO:1904854)
0.9 8.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.7 7.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.7 2.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.6 3.2 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.6 3.9 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.5 8.3 GO:0015232 heme transporter activity(GO:0015232)
0.5 1.5 GO:0005046 KDEL sequence binding(GO:0005046)
0.5 1.5 GO:0005174 CD40 receptor binding(GO:0005174)
0.4 2.6 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.4 4.9 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.4 19.4 GO:0042056 chemoattractant activity(GO:0042056)
0.3 6.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 1.0 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3 3.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 2.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 0.9 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.3 1.4 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.3 2.3 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 1.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 1.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 0.8 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.2 11.4 GO:0001972 retinoic acid binding(GO:0001972)
0.2 2.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 0.8 GO:0001855 complement component C4b binding(GO:0001855)
0.2 2.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 3.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 3.1 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 1.7 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.5 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 1.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.8 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 2.8 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 20.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 3.8 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 3.5 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.8 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 3.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 3.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.5 GO:0031489 myosin V binding(GO:0031489)
0.1 8.7 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 1.7 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 4.2 GO:0017022 myosin binding(GO:0017022)
0.1 8.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.8 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 5.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.2 GO:0015197 peptide transporter activity(GO:0015197)
0.1 6.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.5 GO:0031013 troponin I binding(GO:0031013)
0.0 3.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 2.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 1.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.0 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 4.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 17.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 4.4 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 28.9 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 2.1 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 2.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 5.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.6 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.2 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 5.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 41.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 26.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 17.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 7.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 8.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 6.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 8.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 3.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 24.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 6.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 5.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 3.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.4 PID IGF1 PATHWAY IGF1 pathway
0.0 11.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 9.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 2.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.1 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 12.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.5 25.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.4 13.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 10.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 7.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 3.7 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.3 6.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.3 13.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 7.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 3.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 4.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 2.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 4.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 6.0 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 2.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 5.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 3.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.0 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 4.1 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 3.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.6 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.0 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 1.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family