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Illumina Body Map 2 (GSE30611)

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Results for FOXA2_FOXJ3

Z-value: 1.20

Motif logo

Transcription factors associated with FOXA2_FOXJ3

Gene Symbol Gene ID Gene Info
ENSG00000125798.15 forkhead box A2
ENSG00000198815.9 forkhead box J3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXJ3hg38_v1_chr1_-_42335869_42335891-0.568.6e-04Click!
FOXA2hg38_v1_chr20_-_22585451_225854590.193.1e-01Click!

Activity profile of FOXA2_FOXJ3 motif

Sorted Z-values of FOXA2_FOXJ3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_73404255 9.63 ENST00000621628.4
ENST00000621085.4
ENST00000415165.6
ENST00000295897.9
ENST00000503124.5
ENST00000509063.5
ENST00000401494.7
albumin
chr1_-_161223559 8.30 ENST00000469730.2
ENST00000463273.5
ENST00000464492.5
ENST00000367990.7
ENST00000470459.6
ENST00000463812.1
ENST00000468465.5
apolipoprotein A2
chr1_-_161223408 5.58 ENST00000491350.1
apolipoprotein A2
chr6_+_160702238 5.00 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
plasminogen
chr9_-_101435760 4.79 ENST00000647789.2
ENST00000616752.1
aldolase, fructose-bisphosphate B
chr1_-_169586539 4.45 ENST00000367796.3
coagulation factor V
chr1_-_169586471 4.30 ENST00000367797.9
coagulation factor V
chr1_-_56966133 4.28 ENST00000535057.5
ENST00000543257.5
complement C8 beta chain
chr1_-_56966006 4.12 ENST00000371237.9
complement C8 beta chain
chr1_-_230745574 3.91 ENST00000681269.1
angiotensinogen
chr3_+_109136707 3.58 ENST00000622536.6
chromosome 3 open reading frame 85
chrX_+_71215156 3.36 ENST00000374029.2
ENST00000675209.1
ENST00000647424.1
ENST00000675368.1
ENST00000675609.1
ENST00000646835.1
ENST00000447581.2
gap junction protein beta 1
chr2_+_87748087 3.26 ENST00000359481.9
plasminogen like B2
chr10_+_94938649 3.10 ENST00000461906.1
ENST00000260682.8
cytochrome P450 family 2 subfamily C member 9
chr4_+_186266183 3.09 ENST00000403665.7
ENST00000492972.6
ENST00000264692.8
coagulation factor XI
chr3_+_98732688 3.04 ENST00000486334.6
ENST00000394162.5
ENST00000613264.4
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr12_+_20815672 3.04 ENST00000261196.6
ENST00000381541.7
ENST00000540229.1
solute carrier organic anion transporter family member 1B3
SLCO1B3-SLCO1B7 readthrough
chr1_-_159714581 2.73 ENST00000255030.9
ENST00000437342.1
ENST00000368112.5
ENST00000368111.5
ENST00000368110.1
C-reactive protein
chr3_+_98732236 2.71 ENST00000265261.10
ENST00000483910.5
ENST00000460774.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr11_+_118527463 2.70 ENST00000302783.10
tetratricopeptide repeat domain 36
chr17_-_66220630 2.69 ENST00000585162.1
apolipoprotein H
chr4_-_163613505 2.63 ENST00000339875.9
membrane associated ring-CH-type finger 1
chr4_-_69495897 2.58 ENST00000305107.7
ENST00000639621.1
UDP glucuronosyltransferase family 2 member B4
chr10_+_7703300 2.40 ENST00000358415.9
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7703340 2.39 ENST00000429820.5
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr4_-_69495861 2.36 ENST00000512583.5
UDP glucuronosyltransferase family 2 member B4
chr2_-_87021844 2.27 ENST00000355705.4
ENST00000409310.6
plasminogen like B1
chr14_-_74084393 2.25 ENST00000350259.8
ENST00000553458.6
aldehyde dehydrogenase 6 family member A1
chr2_+_240868817 2.24 ENST00000307503.4
alanine--glyoxylate and serine--pyruvate aminotransferase
chr10_-_100065394 2.12 ENST00000441382.1
carboxypeptidase N subunit 1
chr6_-_160664270 1.92 ENST00000316300.10
lipoprotein(a)
chr8_-_80080816 1.87 ENST00000520527.5
ENST00000517427.5
ENST00000379097.7
ENST00000448733.3
tumor protein D52
chr3_+_98732430 1.87 ENST00000497008.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr4_-_139302516 1.77 ENST00000394228.5
ENST00000539387.5
NADH:ubiquinone oxidoreductase subunit C1
chr2_+_165239432 1.73 ENST00000636071.2
ENST00000636985.2
sodium voltage-gated channel alpha subunit 2
chr8_+_119067239 1.70 ENST00000332843.3
collectin subfamily member 10
chr16_+_56191536 1.67 ENST00000569295.6
G protein subunit alpha o1
chr16_+_6019585 1.66 ENST00000547372.5
RNA binding fox-1 homolog 1
chr12_-_95996302 1.64 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
histidine ammonia-lyase
chr1_+_47137435 1.62 ENST00000371891.8
ENST00000371890.7
ENST00000619754.4
ENST00000294337.7
ENST00000620131.1
cytochrome P450 family 4 subfamily A member 22
chr2_-_71227055 1.56 ENST00000244221.9
poly(A) binding protein interacting protein 2B
chr17_+_7583828 1.55 ENST00000396501.8
ENST00000250124.11
ENST00000584378.5
ENST00000423172.6
ENST00000579445.5
ENST00000585217.5
ENST00000581380.1
mannose-P-dolichol utilization defect 1
chr14_+_88005128 1.55 ENST00000267549.5
G protein-coupled receptor 65
chr1_-_157841800 1.54 ENST00000368174.5
CD5 molecule like
chr4_+_89111521 1.51 ENST00000603357.3
tigger transposable element derived 2
chr5_-_41213021 1.50 ENST00000417809.1
complement C6
chr2_+_142877653 1.49 ENST00000375773.6
ENST00000409512.5
ENST00000264170.9
ENST00000410015.6
kynureninase
chr2_+_165239388 1.49 ENST00000424833.5
ENST00000375437.7
ENST00000631182.3
sodium voltage-gated channel alpha subunit 2
chrX_+_49162564 1.44 ENST00000616266.4
MAGI family member, X-linked
chr6_+_122789197 1.40 ENST00000368440.5
sphingomyelin phosphodiesterase acid like 3A
chr9_+_72114595 1.40 ENST00000545168.5
guanine deaminase
chr16_+_4616475 1.38 ENST00000591895.5
mahogunin ring finger 1
chr16_+_6019016 1.37 ENST00000550418.6
RNA binding fox-1 homolog 1
chr1_+_181483541 1.37 ENST00000367570.5
ENST00000621791.4
calcium voltage-gated channel subunit alpha1 E
chr4_-_139302460 1.32 ENST00000394223.2
ENST00000676245.1
NADH:ubiquinone oxidoreductase subunit C1
chr15_-_53759634 1.32 ENST00000557913.5
ENST00000360509.10
WD repeat domain 72
chrX_+_10156960 1.31 ENST00000380833.9
chloride voltage-gated channel 4
chr1_-_246566238 1.30 ENST00000366514.5
transcription factor B2, mitochondrial
chr4_+_118034480 1.28 ENST00000296499.6
N-deacetylase and N-sulfotransferase 3
chr1_-_206921867 1.28 ENST00000628511.2
ENST00000367091.8
Fc fragment of IgM receptor
chr16_+_6019071 1.26 ENST00000547605.5
ENST00000553186.5
RNA binding fox-1 homolog 1
chr11_+_126327863 1.24 ENST00000648516.1
decapping enzyme, scavenger
chr10_-_127892930 1.24 ENST00000368671.4
clarin 3
chr7_+_26293025 1.22 ENST00000396376.5
sorting nexin 10
chr8_+_66432475 1.21 ENST00000415254.5
ENST00000396623.8
alcohol dehydrogenase iron containing 1
chr2_+_113127588 1.20 ENST00000409930.4
interleukin 1 receptor antagonist
chr13_-_99258366 1.20 ENST00000397470.5
ENST00000397473.7
G protein-coupled receptor 18
chr2_-_2326210 1.19 ENST00000647755.1
myelin transcription factor 1 like
chr1_+_50105666 1.19 ENST00000651347.1
ELAV like RNA binding protein 4
chr3_+_186974957 1.17 ENST00000438590.5
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr16_-_88706262 1.16 ENST00000562544.1
ring finger protein 166
chr1_+_181483510 1.15 ENST00000367573.7
calcium voltage-gated channel subunit alpha1 E
chr2_-_178702479 1.15 ENST00000414766.5
titin
chr1_+_207496229 1.14 ENST00000367051.6
ENST00000367053.6
ENST00000367052.6
complement C3b/C4b receptor 1 (Knops blood group)
chr4_-_110198976 1.10 ENST00000506625.5
ELOVL fatty acid elongase 6
chr16_+_56191476 1.09 ENST00000262493.12
G protein subunit alpha o1
chr7_+_99828010 1.09 ENST00000631161.2
ENST00000354829.7
ENST00000342499.8
ENST00000417625.5
ENST00000415413.5
ENST00000444905.5
ENST00000222382.5
ENST00000312017.9
cytochrome P450 family 3 subfamily A member 43
chr4_+_87799546 1.09 ENST00000226284.7
integrin binding sialoprotein
chr1_-_206921987 1.08 ENST00000530505.1
ENST00000442471.4
Fc fragment of IgM receptor
chr19_-_51751854 1.08 ENST00000304748.5
ENST00000595042.5
formyl peptide receptor 1
chr2_+_174395721 1.06 ENST00000272732.11
ENST00000458563.5
ENST00000409673.7
ENST00000435964.1
ENST00000424069.5
ENST00000427038.5
secernin 3
chr12_-_12561091 1.02 ENST00000539940.1
dual specificity phosphatase 16
chr1_+_207496268 1.02 ENST00000529814.1
complement C3b/C4b receptor 1 (Knops blood group)
chr1_-_160523204 1.02 ENST00000368055.1
ENST00000368057.8
ENST00000368059.7
SLAM family member 6
chr12_-_95995920 1.01 ENST00000552509.5
histidine ammonia-lyase
chr5_-_36241798 1.01 ENST00000514504.5
NAD kinase 2, mitochondrial
chr1_-_216805367 1.00 ENST00000360012.7
estrogen related receptor gamma
chr12_-_12684490 0.99 ENST00000540510.1
G protein-coupled receptor 19
chr4_-_175891691 0.99 ENST00000507540.1
glycoprotein M6A
chr17_-_41309253 0.96 ENST00000391352.1
keratin associated protein 16-1
chr14_+_104801082 0.96 ENST00000342537.8
zinc finger and BTB domain containing 42
chr4_+_87832917 0.95 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr5_+_76875177 0.95 ENST00000613039.1
S100 calcium binding protein Z
chr3_-_58537283 0.95 ENST00000459701.6
acyl-CoA oxidase 2
chr1_+_241532370 0.95 ENST00000366559.9
ENST00000366557.8
kynurenine 3-monooxygenase
chr10_-_50279715 0.94 ENST00000395526.9
N-acylsphingosine amidohydrolase 2
chr5_-_36241875 0.93 ENST00000381937.9
NAD kinase 2, mitochondrial
chr4_-_110199173 0.92 ENST00000503885.1
ELOVL fatty acid elongase 6
chr15_+_58138368 0.92 ENST00000219919.9
ENST00000536493.1
aquaporin 9
chr1_+_44405164 0.91 ENST00000355387.6
ring finger protein 220
chr12_-_12561072 0.91 ENST00000541207.1
dual specificity phosphatase 16
chr2_-_2326378 0.89 ENST00000647618.1
myelin transcription factor 1 like
chr18_+_49562049 0.89 ENST00000261292.9
ENST00000427224.6
ENST00000580036.5
lipase G, endothelial type
chr12_+_28452493 0.88 ENST00000542801.5
coiled-coil domain containing 91
chr1_+_207496147 0.88 ENST00000400960.7
ENST00000367049.9
complement C3b/C4b receptor 1 (Knops blood group)
chr8_-_40897814 0.88 ENST00000297737.11
ENST00000315769.11
zinc finger matrin-type 4
chr1_+_116754422 0.86 ENST00000369478.4
ENST00000369477.1
CD2 molecule
chr15_-_40307910 0.86 ENST00000543785.3
ENST00000260402.8
phospholipase C beta 2
chr12_-_102197827 0.86 ENST00000329406.5
pro-melanin concentrating hormone
chr5_-_36241944 0.85 ENST00000511088.1
ENST00000282512.7
ENST00000506945.5
NAD kinase 2, mitochondrial
chr20_-_1994046 0.85 ENST00000217305.3
ENST00000650874.1
prodynorphin
chr15_-_65029576 0.82 ENST00000220058.9
mitochondrial methionyl-tRNA formyltransferase
chr3_+_190615308 0.82 ENST00000412080.1
interleukin 1 receptor accessory protein
chr3_-_58537181 0.82 ENST00000302819.10
acyl-CoA oxidase 2
chr15_-_40307825 0.82 ENST00000456256.6
ENST00000557821.5
phospholipase C beta 2
chr8_+_86342539 0.80 ENST00000517970.6
WW domain containing E3 ubiquitin protein ligase 1
chr6_+_101398788 0.80 ENST00000369138.5
ENST00000413795.5
ENST00000358361.7
glutamate ionotropic receptor kainate type subunit 2
chr2_-_206213430 0.80 ENST00000447845.1
G protein-coupled receptor 1
chrX_+_121047601 0.80 ENST00000328078.3
glutamate dehydrogenase 2
chr6_+_10528326 0.79 ENST00000379597.7
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr15_-_81324130 0.79 ENST00000302824.7
StAR related lipid transfer domain containing 5
chr3_+_155083889 0.78 ENST00000680282.1
membrane metalloendopeptidase
chr1_+_15526813 0.77 ENST00000375838.5
ENST00000616884.4
ENST00000375849.5
ENST00000375847.8
DnaJ heat shock protein family (Hsp40) member C16
chr15_+_58138169 0.76 ENST00000558772.5
aquaporin 9
chr1_+_198638457 0.76 ENST00000367379.6
protein tyrosine phosphatase receptor type C
chr3_+_155024118 0.75 ENST00000492661.5
membrane metalloendopeptidase
chr6_-_25830557 0.74 ENST00000468082.1
solute carrier family 17 member 1
chr3_-_129656713 0.74 ENST00000510323.1
transmembrane and coiled-coil domain family 1
chr12_-_51324652 0.74 ENST00000544402.5
bridging integrator 2
chr14_+_104800573 0.74 ENST00000555360.1
zinc finger and BTB domain containing 42
chr17_+_7627963 0.73 ENST00000575729.5
ENST00000340624.9
sex hormone binding globulin
chr11_-_126268810 0.73 ENST00000332118.11
SRP receptor subunit alpha
chr18_+_23453275 0.72 ENST00000581585.5
ENST00000339486.8
ENST00000577501.5
RIO kinase 3
chr8_-_63026179 0.71 ENST00000677919.1
gamma-glutamyl hydrolase
chr4_-_64409444 0.70 ENST00000381210.8
ENST00000507440.5
trans-2,3-enoyl-CoA reductase like
chr16_+_48244331 0.70 ENST00000535754.5
lon peptidase 2, peroxisomal
chr19_+_54906140 0.70 ENST00000291890.9
ENST00000598576.5
ENST00000594765.5
ENST00000350790.9
ENST00000338835.9
ENST00000357397.5
natural cytotoxicity triggering receptor 1
chr16_+_48244264 0.70 ENST00000285737.9
lon peptidase 2, peroxisomal
chr2_-_206213362 0.70 ENST00000442134.1
G protein-coupled receptor 1
chr4_+_67558719 0.70 ENST00000265404.7
ENST00000396225.1
signal transducing adaptor family member 1
chr4_-_64409381 0.69 ENST00000509536.1
trans-2,3-enoyl-CoA reductase like
chr14_-_60165293 0.69 ENST00000554101.5
ENST00000557137.1
dehydrogenase/reductase 7
chr4_+_116298876 0.69 ENST00000604093.2
MT-RNR2 like 13
chr1_+_174877430 0.69 ENST00000392064.6
RAB GTPase activating protein 1 like
chr10_-_67838019 0.69 ENST00000483798.6
DnaJ heat shock protein family (Hsp40) member C12
chr3_+_119597874 0.68 ENST00000488919.5
ENST00000273371.9
ENST00000495992.5
phospholipase A1 member A
chr16_+_7332744 0.68 ENST00000436368.6
ENST00000311745.9
ENST00000340209.8
ENST00000620507.4
RNA binding fox-1 homolog 1
chr5_+_65926644 0.68 ENST00000511297.5
ENST00000506030.5
erbb2 interacting protein
chr18_-_50825373 0.68 ENST00000588444.5
ENST00000256425.6
ENST00000428869.6
maestro
chr12_-_54981838 0.68 ENST00000316577.12
thymocyte expressed, positive selection associated 1
chr19_-_50637939 0.67 ENST00000338916.8
synaptotagmin 3
chr18_+_57352541 0.67 ENST00000324000.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr4_-_110198650 0.67 ENST00000394607.7
ELOVL fatty acid elongase 6
chr15_+_90191913 0.66 ENST00000559792.5
semaphorin 4B
chr16_+_10386049 0.66 ENST00000562527.5
ENST00000396559.5
ENST00000396560.6
ENST00000562102.5
ENST00000543967.5
ENST00000569939.5
ENST00000569900.5
activating transcription factor 7 interacting protein 2
chr5_+_167754918 0.66 ENST00000519204.5
teneurin transmembrane protein 2
chr4_-_40630826 0.65 ENST00000505414.5
ENST00000511598.5
RNA binding motif protein 47
chr6_+_146029059 0.65 ENST00000282753.6
glutamate metabotropic receptor 1
chr2_-_36966503 0.64 ENST00000263918.9
striatin
chr19_-_51804104 0.64 ENST00000594900.1
formyl peptide receptor 1
chr1_+_198638723 0.64 ENST00000643513.1
protein tyrosine phosphatase receptor type C
chr4_-_69214743 0.63 ENST00000446444.2
UDP glucuronosyltransferase family 2 member B11
chr16_-_28623560 0.63 ENST00000350842.8
sulfotransferase family 1A member 1
chrX_-_77895546 0.63 ENST00000358075.11
magnesium transporter 1
chrY_-_23694579 0.62 ENST00000343584.10
PTPN13 like Y-linked pseudogene 3
chr6_-_127900958 0.61 ENST00000434358.3
ENST00000630369.2
ENST00000368248.4
thymocyte selection associated
chr19_+_56176006 0.60 ENST00000357330.7
ENST00000440823.1
galanin like peptide
chr17_-_3691887 0.60 ENST00000552050.5
purinergic receptor P2X 5
chr6_+_96924720 0.60 ENST00000369261.9
kelch like family member 32
chr14_-_100569780 0.60 ENST00000355173.7
brain enriched guanylate kinase associated
chr2_-_169573766 0.60 ENST00000438035.5
ENST00000453929.6
FAST kinase domains 1
chr7_+_26291941 0.60 ENST00000412416.5
sorting nexin 10
chr10_-_97334698 0.60 ENST00000371019.4
FRAT regulator of WNT signaling pathway 2
chr10_-_67838173 0.60 ENST00000225171.7
DnaJ heat shock protein family (Hsp40) member C12
chr19_+_3880647 0.60 ENST00000450849.7
ATCAY kinesin light chain interacting caytaxin
chr1_+_198639162 0.59 ENST00000418674.1
protein tyrosine phosphatase receptor type C
chr10_+_122980448 0.59 ENST00000405485.2
phosphoseryl-tRNA kinase
chr12_+_53985065 0.59 ENST00000515593.1
homeobox C10
chr4_+_109848102 0.58 ENST00000594814.6
leucine rich repeat, Ig-like and transmembrane domains 3
chr10_-_124093582 0.58 ENST00000462406.1
ENST00000435907.6
carbohydrate sulfotransferase 15
chr21_-_15002364 0.58 ENST00000411932.1
nuclear receptor interacting protein 1
chr1_-_67054100 0.58 ENST00000235345.6
solute carrier family 35 member D1
chr5_+_161848314 0.58 ENST00000437025.6
gamma-aminobutyric acid type A receptor subunit alpha1
chr19_-_14674886 0.57 ENST00000344373.8
ENST00000595472.1
adhesion G protein-coupled receptor E3
chr1_+_74235377 0.57 ENST00000326637.8
TNNI3 interacting kinase
chr5_+_167754997 0.57 ENST00000520394.5
teneurin transmembrane protein 2
chrX_+_78747705 0.57 ENST00000614823.5
ENST00000435339.3
ENST00000514744.5
lysophosphatidic acid receptor 4
chr3_-_151203201 0.56 ENST00000480322.1
ENST00000309180.6
G protein-coupled receptor 171
chr19_+_18097763 0.56 ENST00000262811.10
microtubule associated serine/threonine kinase 3
chr15_-_58749569 0.56 ENST00000402627.5
ENST00000559053.1
ENST00000260408.8
ENST00000561288.1
ENST00000461408.2
ENST00000439637.5
ENST00000558004.1
ADAM metallopeptidase domain 10
chr12_+_71686473 0.55 ENST00000549735.5
transmembrane protein 19
chr3_+_155083523 0.55 ENST00000680057.1
membrane metalloendopeptidase
chr9_+_124291935 0.55 ENST00000546191.5
NIMA related kinase 6
chr13_-_61415508 0.54 ENST00000409204.4
protocadherin 20
chr4_+_183905266 0.54 ENST00000308497.9
storkhead box 2
chr8_-_144529048 0.54 ENST00000527462.1
ENST00000313465.5
ENST00000524821.6
chromosome 8 open reading frame 82
chrX_+_86714623 0.54 ENST00000484479.1
dachshund family transcription factor 2
chr1_+_44674688 0.53 ENST00000418644.5
ENST00000458657.6
ENST00000535358.6
ENST00000441519.5
ENST00000445071.5
armadillo like helical domain containing 1
chr12_-_62191422 0.53 ENST00000551449.1
TAFA chemokine like family member 2
chr2_-_227614840 0.53 ENST00000642029.1
small cysteine and glycine repeat containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA2_FOXJ3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 13.9 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
3.2 9.6 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
2.0 8.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
1.6 4.9 GO:0006711 estrogen catabolic process(GO:0006711)
1.5 8.8 GO:0032571 response to vitamin K(GO:0032571)
1.3 3.9 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
1.0 3.0 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.6 2.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.6 2.2 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.5 1.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.5 1.5 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.5 1.9 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.5 4.8 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.5 1.4 GO:0006147 guanine catabolic process(GO:0006147)
0.5 2.3 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.5 7.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 3.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.4 1.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.4 2.1 GO:0030070 insulin processing(GO:0030070)
0.4 1.2 GO:0036245 cellular response to menadione(GO:0036245)
0.4 1.2 GO:0015993 molecular hydrogen transport(GO:0015993)
0.4 1.2 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.4 2.6 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.4 1.1 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.3 2.8 GO:0006741 NADP biosynthetic process(GO:0006741)
0.3 1.0 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.3 1.7 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.3 1.6 GO:0002933 lipid hydroxylation(GO:0002933)
0.2 0.7 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.2 0.7 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 0.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 0.7 GO:1903970 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.2 0.7 GO:0045175 basal protein localization(GO:0045175)
0.2 2.7 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392) negative regulation of fibrinolysis(GO:0051918)
0.2 0.9 GO:0010983 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.2 1.0 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.2 0.6 GO:0001543 ovarian follicle rupture(GO:0001543)
0.2 2.7 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 3.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 0.6 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.2 0.5 GO:0070541 response to platinum ion(GO:0070541)
0.2 0.5 GO:0036451 cap mRNA methylation(GO:0036451)
0.2 1.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.2 8.6 GO:0097503 sialylation(GO:0097503)
0.2 2.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 1.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.2 0.5 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.2 0.6 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 1.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.6 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1 0.4 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.7 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 3.4 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 2.7 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.1 1.7 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 1.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.4 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 0.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 2.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 1.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.5 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.7 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.6 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.3 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.8 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.5 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 0.4 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.1 0.3 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.1 0.3 GO:0042309 homoiothermy(GO:0042309)
0.1 0.8 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 2.4 GO:0097264 self proteolysis(GO:0097264)
0.1 0.3 GO:0035928 mitochondrial RNA 5'-end processing(GO:0000964) rRNA import into mitochondrion(GO:0035928) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.1 1.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 2.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.9 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.1 1.7 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.1 0.7 GO:0035696 monocyte extravasation(GO:0035696)
0.1 0.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.2 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.1 0.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.3 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.1 0.3 GO:0045014 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 1.9 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.2 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.5 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 3.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.2 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.1 0.4 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 5.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.4 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.3 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 0.8 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 3.1 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.1 0.6 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.1 1.3 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.3 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.1 1.5 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 0.9 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 1.5 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.3 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.1 0.5 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.5 GO:1902261 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051) positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 4.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:1903758 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.2 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 5.4 GO:0006968 cellular defense response(GO:0006968)
0.0 0.4 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.5 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.7 GO:0046415 urate metabolic process(GO:0046415)
0.0 2.8 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.2 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 3.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 5.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.4 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 1.6 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 1.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.1 GO:0036404 positive regulation of Schwann cell differentiation(GO:0014040) conversion of ds siRNA to ss siRNA involved in RNA interference(GO:0033168) conversion of ds siRNA to ss siRNA(GO:0036404)
0.0 0.7 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.5 GO:0002858 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.0 0.6 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.4 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.2 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.0 0.2 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 1.2 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.2 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 1.3 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.3 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 1.1 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.8 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.4 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.3 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.4 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.6 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.4 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.4 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.7 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0060903 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 1.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.7 GO:0007035 vacuolar acidification(GO:0007035) ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.7 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.5 GO:0009651 response to salt stress(GO:0009651)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.6 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0043320 natural killer cell degranulation(GO:0043320)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.0 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.7 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 4.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.0 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579) gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.0 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069) negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0046851 negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851)
0.0 0.4 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 9.9 GO:0005579 membrane attack complex(GO:0005579)
0.9 5.3 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.7 13.9 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.4 1.5 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.2 1.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 18.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.6 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 2.7 GO:0042627 chylomicron(GO:0042627)
0.1 3.4 GO:0005922 connexon complex(GO:0005922)
0.1 3.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 4.8 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.5 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 6.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.4 GO:0061617 MICOS complex(GO:0061617)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 0.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.5 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.1 0.9 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 2.0 GO:1990777 plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.1 0.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 1.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 3.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0032010 phagolysosome(GO:0032010)
0.0 0.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 5.6 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0033167 ARC complex(GO:0033167)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 2.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 1.3 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 1.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0043194 axon initial segment(GO:0043194)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 5.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 2.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 6.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.4 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.7 GO:0030315 T-tubule(GO:0030315)
0.0 12.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 9.5 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 13.9 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.8 5.5 GO:1904854 proteasome core complex binding(GO:1904854)
1.5 7.6 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
1.2 4.8 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
1.0 3.0 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.7 2.2 GO:0033791 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity(GO:0033791)
0.7 2.7 GO:0033265 choline binding(GO:0033265)
0.6 3.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.5 1.4 GO:0008892 guanine deaminase activity(GO:0008892)
0.4 2.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.4 9.6 GO:0015643 toxic substance binding(GO:0015643)
0.4 1.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.4 2.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.4 2.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.3 1.0 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.3 1.7 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.3 1.5 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 1.7 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.2 0.7 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.2 0.6 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.2 0.8 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 2.7 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 1.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 2.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 0.5 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.2 2.6 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960)
0.2 3.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.2 3.4 GO:0005243 gap junction channel activity(GO:0005243)
0.2 1.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 5.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 1.3 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 0.4 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.1 0.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 3.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.8 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.4 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 1.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.5 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 1.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.5 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 0.5 GO:0047708 biotinidase activity(GO:0047708)
0.1 5.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.7 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.2 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.1 0.6 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.8 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 1.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 1.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.9 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.7 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 1.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.8 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.7 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.6 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.7 GO:0005497 androgen binding(GO:0005497)
0.1 0.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 8.7 GO:0005507 copper ion binding(GO:0005507)
0.1 3.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.0 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 1.7 GO:0005537 mannose binding(GO:0005537)
0.1 0.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 1.3 GO:0031433 telethonin binding(GO:0031433)
0.1 0.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.7 GO:0089720 caspase binding(GO:0089720)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 1.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 1.9 GO:0008527 taste receptor activity(GO:0008527)
0.1 1.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 3.0 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 2.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 2.0 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.6 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 3.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.6 GO:0031013 troponin I binding(GO:0031013)
0.1 0.3 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 0.3 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.5 GO:0019863 IgE binding(GO:0019863)
0.1 1.1 GO:0070330 aromatase activity(GO:0070330)
0.1 0.8 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 2.1 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 2.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 1.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.4 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.7 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.8 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.0 0.8 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 1.0 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.3 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 1.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 1.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.4 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 1.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.7 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.0 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 4.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 1.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.6 GO:0016502 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 0.7 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.4 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877) cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.0 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 1.4 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 1.0 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.0 GO:0008940 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 3.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 14.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 4.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 6.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.5 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 2.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.0 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 12.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.6 13.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.5 8.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 16.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 8.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 6.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 5.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 3.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 3.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 3.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.9 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.1 2.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 1.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 2.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 2.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 3.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 0.8 REACTOME OPSINS Genes involved in Opsins
0.1 0.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 4.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 4.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.0 1.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 5.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.5 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.8 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.6 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 2.4 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 4.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 1.1 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 3.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.4 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.1 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis