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Illumina Body Map 2 (GSE30611)

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Results for FOXA3_FOXC2

Z-value: 1.36

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Transcription factors associated with FOXA3_FOXC2

Gene Symbol Gene ID Gene Info
FOXA3
ENSG00000170608.3 forkhead box A3
FOXC2
ENSG00000176692.8 forkhead box C2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXA3hg38_v1_chr19_+_45864318_458643340.594.1e-04Click!
FOXC2hg38_v1_chr16_+_86566821_865668360.019.6e-01Click!

Activity profile of FOXA3_FOXC2 motif

Sorted Z-values of FOXA3_FOXC2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_62419025 13.41 ENST00000278282.3
SCGB1A1
secretoglobin family 1A member 1
chr1_-_56966133 8.31 ENST00000535057.5
ENST00000543257.5
C8B
complement C8 beta chain
chr11_-_116837586 7.91 ENST00000375320.5
ENST00000359492.6
ENST00000375329.6
ENST00000375323.5
ENST00000236850.5
APOA1
apolipoprotein A1
chr17_-_28368012 7.46 ENST00000555059.2
ENSG00000273171.1
novel protein, readthrough between VTN and SEBOX
chr1_-_56966006 7.45 ENST00000371237.9
C8B
complement C8 beta chain
chr8_+_119067239 5.59 ENST00000332843.3
COLEC10
collectin subfamily member 10
chr1_+_207104226 4.71 ENST00000367070.8
C4BPA
complement component 4 binding protein alpha
chr2_+_127418420 4.65 ENST00000234071.8
ENST00000429925.5
ENST00000442644.5
PROC
protein C, inactivator of coagulation factors Va and VIIIa
chr6_-_41747390 4.44 ENST00000356667.8
ENST00000373025.7
ENST00000425343.6
PGC
progastricsin
chr14_+_20688756 3.96 ENST00000397990.5
ENST00000555597.1
ANG
RNASE4
angiogenin
ribonuclease A family member 4
chr4_-_99144238 3.67 ENST00000512499.5
ENST00000504125.1
ENST00000505590.5
ENST00000629236.2
ENST00000508393.5
ENST00000265512.12
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr3_+_109136707 3.66 ENST00000622536.6
C3orf85
chromosome 3 open reading frame 85
chr1_+_207104287 3.64 ENST00000421786.5
C4BPA
complement component 4 binding protein alpha
chr4_+_186266183 3.62 ENST00000403665.7
ENST00000492972.6
ENST00000264692.8
F11
coagulation factor XI
chr3_+_137998735 3.60 ENST00000343735.8
CLDN18
claudin 18
chr22_+_20774092 3.53 ENST00000215727.10
SERPIND1
serpin family D member 1
chr4_-_70666492 3.46 ENST00000254801.9
ENST00000391614.7
JCHAIN
joining chain of multimeric IgA and IgM
chr10_+_69801892 3.45 ENST00000398978.8
ENST00000645393.2
ENST00000354547.7
ENST00000674121.1
ENST00000673842.1
ENST00000520267.5
COL13A1
collagen type XIII alpha 1 chain
chr17_-_28370283 3.41 ENST00000226218.9
VTN
vitronectin
chr14_-_69797232 3.29 ENST00000216540.5
SLC10A1
solute carrier family 10 member 1
chr2_-_21044063 3.27 ENST00000233242.5
APOB
apolipoprotein B
chr11_-_6440980 3.19 ENST00000265983.8
ENST00000615166.1
HPX
hemopexin
chr17_+_9021501 3.05 ENST00000173229.7
NTN1
netrin 1
chr3_+_138010143 2.87 ENST00000183605.10
CLDN18
claudin 18
chr20_+_33235987 2.87 ENST00000375422.6
ENST00000375413.8
ENST00000354297.9
BPIFA1
BPI fold containing family A member 1
chr4_+_73404255 2.86 ENST00000621628.4
ENST00000621085.4
ENST00000415165.6
ENST00000295897.9
ENST00000503124.5
ENST00000509063.5
ENST00000401494.7
ALB
albumin
chr5_-_41213505 2.85 ENST00000337836.10
ENST00000433294.1
C6
complement C6
chr2_+_134838610 2.83 ENST00000356140.10
ENST00000392928.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr4_-_70666884 2.82 ENST00000510614.5
JCHAIN
joining chain of multimeric IgA and IgM
chr5_-_41213021 2.81 ENST00000417809.1
C6
complement C6
chr15_+_58138368 2.80 ENST00000219919.9
ENST00000536493.1
AQP9
aquaporin 9
chr17_-_19387170 2.73 ENST00000395592.6
ENST00000299610.5
MFAP4
microfibril associated protein 4
chr17_-_31314040 2.69 ENST00000330927.5
EVI2B
ecotropic viral integration site 2B
chr4_-_70666961 2.67 ENST00000510437.5
JCHAIN
joining chain of multimeric IgA and IgM
chr6_+_160702238 2.57 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
PLG
plasminogen
chr10_-_116273009 2.51 ENST00000439649.8
ENST00000369234.5
ENST00000682194.1
ENST00000355422.11
GFRA1
GDNF family receptor alpha 1
chr4_-_71784046 2.49 ENST00000513476.5
ENST00000273951.13
GC
GC vitamin D binding protein
chr1_-_169586539 2.40 ENST00000367796.3
F5
coagulation factor V
chr14_-_94323324 2.38 ENST00000341584.4
SERPINA6
serpin family A member 6
chr2_+_113127588 2.38 ENST00000409930.4
IL1RN
interleukin 1 receptor antagonist
chr1_-_169586471 2.36 ENST00000367797.9
F5
coagulation factor V
chr17_-_31314066 2.35 ENST00000577894.1
EVI2B
ecotropic viral integration site 2B
chr7_-_81770039 2.33 ENST00000222390.11
ENST00000453411.6
ENST00000457544.7
ENST00000444829.7
HGF
hepatocyte growth factor
chr20_-_7940444 2.32 ENST00000378789.4
HAO1
hydroxyacid oxidase 1
chr20_+_33283205 2.25 ENST00000253354.2
BPIFB1
BPI fold containing family B member 1
chr4_+_186227501 2.23 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
KLKB1
kallikrein B1
chr17_-_59151794 2.23 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr2_+_87748087 2.22 ENST00000359481.9
PLGLB2
plasminogen like B2
chr7_+_143132069 2.20 ENST00000291009.4
PIP
prolactin induced protein
chr5_+_147878703 2.19 ENST00000296694.5
SCGB3A2
secretoglobin family 3A member 2
chr4_+_168092530 2.09 ENST00000359299.8
ANXA10
annexin A10
chr2_-_87021844 2.06 ENST00000355705.4
ENST00000409310.6
PLGLB1
plasminogen like B1
chr15_+_58138169 2.04 ENST00000558772.5
AQP9
aquaporin 9
chr3_+_114294020 2.00 ENST00000383671.8
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr13_-_85799400 1.98 ENST00000647374.2
SLITRK6
SLIT and NTRK like family member 6
chr4_-_69495897 1.91 ENST00000305107.7
ENST00000639621.1
UGT2B4
UDP glucuronosyltransferase family 2 member B4
chrX_+_136648138 1.83 ENST00000370629.7
CD40LG
CD40 ligand
chr14_-_94323389 1.76 ENST00000557225.1
SERPINA6
serpin family A member 6
chr4_-_69495861 1.71 ENST00000512583.5
UGT2B4
UDP glucuronosyltransferase family 2 member B4
chr10_-_116273606 1.70 ENST00000682743.1
GFRA1
GDNF family receptor alpha 1
chr7_-_81770122 1.63 ENST00000423064.7
HGF
hepatocyte growth factor
chr10_+_69802424 1.61 ENST00000673802.2
ENST00000517713.5
ENST00000520133.5
ENST00000522165.5
ENST00000673641.2
ENST00000673628.2
COL13A1
collagen type XIII alpha 1 chain
chr2_-_21043941 1.54 ENST00000399256.4
APOB
apolipoprotein B
chr17_+_4710622 1.51 ENST00000574954.5
ENST00000269260.7
ENST00000346341.6
ENST00000572457.5
ENST00000381488.10
ENST00000412477.7
ENST00000571428.5
ENST00000575877.5
ARRB2
arrestin beta 2
chr4_+_89879532 1.51 ENST00000394980.5
MMRN1
multimerin 1
chrX_-_15384402 1.49 ENST00000297904.4
VEGFD
vascular endothelial growth factor D
chr10_-_79949098 1.44 ENST00000372292.8
SFTPD
surfactant protein D
chr6_-_159045104 1.40 ENST00000326965.7
TAGAP
T cell activation RhoGTPase activating protein
chr17_-_39864140 1.38 ENST00000623724.3
ENST00000439167.6
ENST00000377945.7
ENST00000394189.6
ENST00000377944.7
ENST00000377958.6
ENST00000535189.5
ENST00000377952.6
IKZF3
IKAROS family zinc finger 3
chr9_-_107489754 1.36 ENST00000610832.1
ENST00000374672.5
KLF4
Kruppel like factor 4
chr13_-_48413105 1.34 ENST00000620633.5
LPAR6
lysophosphatidic acid receptor 6
chr1_+_74235377 1.31 ENST00000326637.8
TNNI3K
TNNI3 interacting kinase
chr10_+_122560639 1.28 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
DMBT1
deleted in malignant brain tumors 1
chr2_-_187448244 1.28 ENST00000392370.8
ENST00000410068.5
ENST00000447403.5
ENST00000410102.5
CALCRL
calcitonin receptor like receptor
chr21_-_14658812 1.27 ENST00000647101.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr7_-_81770013 1.26 ENST00000465234.2
HGF
hepatocyte growth factor
chr8_+_19313685 1.25 ENST00000265807.8
ENST00000518040.5
SH2D4A
SH2 domain containing 4A
chr11_-_57390636 1.25 ENST00000525955.1
ENST00000533605.5
ENST00000311862.10
PRG2
proteoglycan 2, pro eosinophil major basic protein
chr4_-_102345469 1.24 ENST00000356736.5
ENST00000682932.1
SLC39A8
solute carrier family 39 member 8
chr6_+_142302621 1.23 ENST00000541199.5
ENST00000435011.6
ADGRG6
adhesion G protein-coupled receptor G6
chr17_+_42998379 1.22 ENST00000253788.12
ENST00000589913.6
RPL27
ribosomal protein L27
chrX_+_136648214 1.19 ENST00000370628.2
CD40LG
CD40 ligand
chr7_+_134891566 1.19 ENST00000424922.5
ENST00000495522.1
CALD1
caldesmon 1
chr15_+_96325935 1.19 ENST00000421109.6
NR2F2
nuclear receptor subfamily 2 group F member 2
chr4_+_15427998 1.18 ENST00000444304.3
C1QTNF7
C1q and TNF related 7
chr18_+_49562049 1.15 ENST00000261292.9
ENST00000427224.6
ENST00000580036.5
LIPG
lipase G, endothelial type
chr2_-_207165923 1.13 ENST00000309446.11
KLF7
Kruppel like factor 7
chr12_-_21775581 1.13 ENST00000537950.1
ENST00000665145.1
KCNJ8
potassium inwardly rectifying channel subfamily J member 8
chr17_-_39864304 1.13 ENST00000346872.8
IKZF3
IKAROS family zinc finger 3
chr12_+_12891554 1.12 ENST00000014914.6
GPRC5A
G protein-coupled receptor class C group 5 member A
chr11_+_126327863 1.11 ENST00000648516.1
DCPS
decapping enzyme, scavenger
chr6_-_160664270 1.09 ENST00000316300.10
LPA
lipoprotein(a)
chr13_-_38990824 1.07 ENST00000379631.9
STOML3
stomatin like 3
chr12_+_80099535 1.07 ENST00000646859.1
ENST00000547103.7
OTOGL
otogelin like
chr12_+_12891853 1.06 ENST00000534831.1
GPRC5A
G protein-coupled receptor class C group 5 member A
chr7_-_81770362 1.06 ENST00000412881.5
HGF
hepatocyte growth factor
chr14_+_22829879 1.04 ENST00000355151.9
ENST00000397496.7
ENST00000555345.5
ENST00000432849.7
ENST00000553711.5
ENST00000556465.5
ENST00000397505.2
ENST00000557221.1
ENST00000556840.5
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr5_+_136058849 1.03 ENST00000508076.5
TGFBI
transforming growth factor beta induced
chr7_+_134779663 1.03 ENST00000361901.6
CALD1
caldesmon 1
chr2_+_73892967 1.03 ENST00000409731.7
ENST00000409918.5
ENST00000442912.5
ENST00000345517.8
ENST00000409624.1
ACTG2
actin gamma 2, smooth muscle
chr10_+_69801874 1.02 ENST00000357811.8
COL13A1
collagen type XIII alpha 1 chain
chr17_-_39864126 1.02 ENST00000351680.7
ENST00000346243.7
ENST00000350532.7
ENST00000467757.5
ENST00000439016.2
IKZF3
IKAROS family zinc finger 3
chr16_-_87936529 1.02 ENST00000649794.3
ENST00000649158.1
ENST00000648177.1
CA5A
carbonic anhydrase 5A
chr7_-_81769971 1.01 ENST00000354224.10
ENST00000643024.1
HGF
hepatocyte growth factor
chr1_-_206921867 1.01 ENST00000628511.2
ENST00000367091.8
FCMR
Fc fragment of IgM receptor
chr10_+_122560751 1.01 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
DMBT1
deleted in malignant brain tumors 1
chr3_+_119597874 1.00 ENST00000488919.5
ENST00000273371.9
ENST00000495992.5
PLA1A
phospholipase A1 member A
chr2_-_206213362 1.00 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr3_+_132597260 0.98 ENST00000249887.3
ACKR4
atypical chemokine receptor 4
chr5_+_134524305 0.95 ENST00000431355.2
JADE2
jade family PHD finger 2
chr16_-_48247533 0.93 ENST00000356608.7
ENST00000569991.1
ABCC11
ATP binding cassette subfamily C member 11
chr15_+_75647877 0.93 ENST00000308527.6
SNX33
sorting nexin 33
chr12_+_59596137 0.92 ENST00000549465.5
SLC16A7
solute carrier family 16 member 7
chr12_-_102197827 0.90 ENST00000329406.5
PMCH
pro-melanin concentrating hormone
chr2_+_68365274 0.89 ENST00000234313.8
PLEK
pleckstrin
chr10_-_124093582 0.89 ENST00000462406.1
ENST00000435907.6
CHST15
carbohydrate sulfotransferase 15
chr17_-_41528293 0.89 ENST00000455635.1
ENST00000361566.7
KRT19
keratin 19
chr18_-_54959391 0.88 ENST00000591504.6
CCDC68
coiled-coil domain containing 68
chr8_+_96584920 0.88 ENST00000521590.5
SDC2
syndecan 2
chr6_-_159044980 0.88 ENST00000367066.8
TAGAP
T cell activation RhoGTPase activating protein
chr11_-_108593738 0.87 ENST00000525344.5
ENST00000265843.9
EXPH5
exophilin 5
chr13_-_38990856 0.87 ENST00000423210.1
STOML3
stomatin like 3
chr8_-_63026179 0.87 ENST00000677919.1
GGH
gamma-glutamyl hydrolase
chr12_-_21775045 0.87 ENST00000667884.1
KCNJ8
potassium inwardly rectifying channel subfamily J member 8
chr21_-_34615103 0.85 ENST00000313806.9
RCAN1
regulator of calcineurin 1
chr7_+_134891400 0.85 ENST00000393118.6
CALD1
caldesmon 1
chr1_-_206921987 0.79 ENST00000530505.1
ENST00000442471.4
FCMR
Fc fragment of IgM receptor
chr7_-_142813394 0.79 ENST00000417977.2
TRBV30
T cell receptor beta variable 30
chr9_-_37034031 0.79 ENST00000520281.5
ENST00000446742.5
ENST00000522003.5
ENST00000523145.5
ENST00000414447.5
ENST00000377847.6
ENST00000377853.6
PAX5
paired box 5
chr14_-_99272184 0.79 ENST00000357195.8
BCL11B
BAF chromatin remodeling complex subunit BCL11B
chr9_-_4299873 0.79 ENST00000477901.5
GLIS3
GLIS family zinc finger 3
chr7_+_134779625 0.75 ENST00000454108.5
ENST00000361675.7
CALD1
caldesmon 1
chr17_+_7583828 0.74 ENST00000396501.8
ENST00000250124.11
ENST00000584378.5
ENST00000423172.6
ENST00000579445.5
ENST00000585217.5
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr10_+_69088096 0.73 ENST00000242465.4
SRGN
serglycin
chr4_-_151325488 0.73 ENST00000604030.7
SH3D19
SH3 domain containing 19
chr3_+_141387801 0.72 ENST00000514251.5
ZBTB38
zinc finger and BTB domain containing 38
chr2_-_207165571 0.72 ENST00000458272.1
KLF7
Kruppel like factor 7
chr16_+_56191536 0.72 ENST00000569295.6
GNAO1
G protein subunit alpha o1
chr14_-_99271485 0.71 ENST00000345514.2
ENST00000443726.2
BCL11B
BAF chromatin remodeling complex subunit BCL11B
chr9_+_4839761 0.71 ENST00000448872.6
ENST00000441844.2
RCL1
RNA terminal phosphate cyclase like 1
chr13_-_74133892 0.71 ENST00000377669.7
KLF12
Kruppel like factor 12
chr6_-_26056460 0.70 ENST00000343677.4
H1-2
H1.2 linker histone, cluster member
chr8_-_70245343 0.69 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chr10_+_122560679 0.68 ENST00000657942.1
DMBT1
deleted in malignant brain tumors 1
chr15_-_40307825 0.68 ENST00000456256.6
ENST00000557821.5
PLCB2
phospholipase C beta 2
chr1_-_167553799 0.67 ENST00000466652.2
CREG1
cellular repressor of E1A stimulated genes 1
chr14_+_36657560 0.67 ENST00000402703.6
PAX9
paired box 9
chr3_-_149792547 0.67 ENST00000446160.7
ENST00000462519.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr17_+_7572818 0.67 ENST00000293831.13
ENST00000582169.5
ENST00000578754.5
ENST00000578495.5
ENST00000585024.5
ENST00000583802.5
ENST00000577269.5
ENST00000584784.5
ENST00000582746.5
ENST00000581621.1
EIF4A1
ENSG00000264772.6
eukaryotic translation initiation factor 4A1
novel transcript
chr15_-_40307910 0.66 ENST00000543785.3
ENST00000260402.8
PLCB2
phospholipase C beta 2
chr8_-_132760548 0.66 ENST00000519187.5
ENST00000523829.5
ENST00000677595.1
ENST00000356838.7
ENST00000377901.8
ENST00000519304.1
TMEM71
transmembrane protein 71
chr6_-_159045010 0.65 ENST00000338313.5
TAGAP
T cell activation RhoGTPase activating protein
chr14_-_25010604 0.64 ENST00000550887.5
STXBP6
syntaxin binding protein 6
chr7_-_107803215 0.63 ENST00000340010.10
ENST00000453332.1
SLC26A3
solute carrier family 26 member 3
chr9_+_110090197 0.62 ENST00000480388.1
PALM2AKAP2
PALM2 and AKAP2 fusion
chr15_-_58749569 0.62 ENST00000402627.5
ENST00000559053.1
ENST00000260408.8
ENST00000561288.1
ENST00000461408.2
ENST00000439637.5
ENST00000558004.1
ADAM10
ADAM metallopeptidase domain 10
chr7_-_22220226 0.62 ENST00000420196.5
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr4_-_151227881 0.61 ENST00000652233.1
ENST00000514152.5
SH3D19
SH3 domain containing 19
chr1_-_177969907 0.60 ENST00000308284.10
SEC16B
SEC16 homolog B, endoplasmic reticulum export factor
chr12_-_102478539 0.60 ENST00000424202.6
IGF1
insulin like growth factor 1
chr5_-_138338325 0.59 ENST00000510119.1
ENST00000513970.5
CDC25C
cell division cycle 25C
chr1_+_103656018 0.59 ENST00000422549.1
AMY1A
amylase alpha 1A
chr4_+_87799546 0.58 ENST00000226284.7
IBSP
integrin binding sialoprotein
chr7_-_81770428 0.57 ENST00000421558.1
HGF
hepatocyte growth factor
chr4_+_15339818 0.57 ENST00000397700.6
ENST00000295297.4
C1QTNF7
C1q and TNF related 7
chr8_+_74824526 0.57 ENST00000649643.1
ENST00000260113.7
PI15
peptidase inhibitor 15
chr7_-_108003122 0.56 ENST00000393559.2
ENST00000222399.11
ENST00000676777.1
ENST00000439976.6
ENST00000393560.5
ENST00000677793.1
ENST00000679244.1
LAMB1
laminin subunit beta 1
chr9_-_37034185 0.56 ENST00000520154.6
PAX5
paired box 5
chr6_+_44342639 0.54 ENST00000674044.1
ENST00000515220.5
ENST00000323108.12
SPATS1
spermatogenesis associated serine rich 1
chr13_-_99258366 0.54 ENST00000397470.5
ENST00000397473.7
GPR18
G protein-coupled receptor 18
chr6_-_130890393 0.53 ENST00000456097.6
EPB41L2
erythrocyte membrane protein band 4.1 like 2
chr16_+_20763990 0.53 ENST00000289416.10
ACSM3
acyl-CoA synthetase medium chain family member 3
chr1_+_222928415 0.52 ENST00000284476.7
DISP1
dispatched RND transporter family member 1
chr5_-_170297746 0.51 ENST00000046794.10
LCP2
lymphocyte cytosolic protein 2
chr16_+_20764036 0.50 ENST00000440284.6
ACSM3
acyl-CoA synthetase medium chain family member 3
chr4_-_115113614 0.49 ENST00000264363.7
NDST4
N-deacetylase and N-sulfotransferase 4
chr1_-_167553745 0.47 ENST00000370509.5
CREG1
cellular repressor of E1A stimulated genes 1
chr10_+_35195124 0.47 ENST00000487763.5
ENST00000473940.5
ENST00000488328.5
ENST00000356917.9
CREM
cAMP responsive element modulator
chr7_-_111784448 0.46 ENST00000450156.6
DOCK4
dedicator of cytokinesis 4
chr6_+_44342684 0.46 ENST00000288390.2
SPATS1
spermatogenesis associated serine rich 1
chr6_-_112254555 0.46 ENST00000230538.12
ENST00000389463.9
ENST00000368638.5
ENST00000431543.6
ENST00000453937.2
LAMA4
laminin subunit alpha 4
chr17_-_41315706 0.46 ENST00000334202.5
KRTAP17-1
keratin associated protein 17-1
chr7_+_134745460 0.46 ENST00000436461.6
CALD1
caldesmon 1
chr7_+_114414809 0.45 ENST00000350908.9
FOXP2
forkhead box P2
chr1_+_40396766 0.45 ENST00000539317.2
SMAP2
small ArfGAP2
chr6_-_112254647 0.45 ENST00000455073.1
ENST00000522006.5
ENST00000519932.5
LAMA4
laminin subunit alpha 4
chr4_-_115113822 0.44 ENST00000613194.4
NDST4
N-deacetylase and N-sulfotransferase 4
chr1_+_23691742 0.43 ENST00000374550.8
ENST00000643754.2
RPL11
ribosomal protein L11
chr11_+_65890627 0.43 ENST00000312579.4
CCDC85B
coiled-coil domain containing 85B
chr14_+_104800573 0.42 ENST00000555360.1
ZBTB42
zinc finger and BTB domain containing 42
chr4_+_145482761 0.42 ENST00000507367.1
ENST00000394092.6
ENST00000515385.1
SMAD1
SMAD family member 1
chr8_+_54616057 0.42 ENST00000637698.1
RP1
RP1 axonemal microtubule associated
chr20_+_9069095 0.42 ENST00000437503.5
PLCB4
phospholipase C beta 4
chr12_-_121580441 0.42 ENST00000377069.8
KDM2B
lysine demethylase 2B
chr4_-_139302516 0.41 ENST00000394228.5
ENST00000539387.5
NDUFC1
NADH:ubiquinone oxidoreductase subunit C1
chr22_-_30471986 0.41 ENST00000401751.5
ENST00000402286.5
ENST00000403066.5
ENST00000215812.9
SEC14L3
SEC14 like lipid binding 3
chr17_+_76376581 0.41 ENST00000591651.5
ENST00000545180.5
SPHK1
sphingosine kinase 1
chr12_+_103930600 0.41 ENST00000680316.1
ENST00000679861.1
HSP90B1
heat shock protein 90 beta family member 1
chr3_+_172040554 0.41 ENST00000336824.8
ENST00000423424.5
FNDC3B
fibronectin type III domain containing 3B
chr8_-_6563409 0.41 ENST00000325203.9
ANGPT2
angiopoietin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA3_FOXC2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 13.4 GO:0010193 response to ozone(GO:0010193)
2.1 8.4 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
1.9 5.7 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.6 7.9 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
1.2 3.6 GO:0006711 estrogen catabolic process(GO:0006711)
1.2 4.7 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
1.0 15.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.0 4.8 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
1.0 2.9 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.9 2.8 GO:1902688 regulation of NAD metabolic process(GO:1902688)
0.9 8.4 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.8 8.9 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.8 4.8 GO:0032571 response to vitamin K(GO:0032571)
0.7 4.4 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.7 4.4 GO:0008218 bioluminescence(GO:0008218)
0.7 2.9 GO:1900190 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.7 7.9 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.6 4.8 GO:0034371 chylomicron remodeling(GO:0034371)
0.5 6.5 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.5 4.0 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.5 3.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.4 1.5 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.4 1.5 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.4 1.1 GO:0036245 cellular response to menadione(GO:0036245)
0.4 2.9 GO:0009441 glycolate metabolic process(GO:0009441)
0.3 1.4 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.3 3.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 4.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 1.2 GO:0002215 defense response to nematode(GO:0002215)
0.3 5.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 2.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 1.2 GO:0009956 radial pattern formation(GO:0009956)
0.3 1.2 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.2 0.7 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 4.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 2.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 2.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 2.0 GO:0060005 vestibular reflex(GO:0060005)
0.2 3.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 3.8 GO:0006069 ethanol oxidation(GO:0006069)
0.2 0.7 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.2 0.5 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 0.9 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 0.7 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.2 0.5 GO:0007225 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.2 1.0 GO:0090131 mesenchyme migration(GO:0090131)
0.2 1.5 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.2 0.5 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.1 0.4 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.4 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.4 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.4 GO:1904266 positive regulation of Schwann cell migration(GO:1900149) regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.1 1.3 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.9 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.1 0.8 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.6 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.8 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.3 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 1.2 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 4.1 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 2.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.4 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 0.3 GO:0019878 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.1 5.0 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.1 0.3 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.1 0.4 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 1.3 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 2.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 2.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 2.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.7 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 2.2 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.1 1.1 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 6.1 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 3.5 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.6 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 1.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.1 1.2 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.3 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 1.5 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.1 0.9 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 2.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.3 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.3 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.6 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 1.1 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.8 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.0 0.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.6 GO:0051601 exocyst localization(GO:0051601)
0.0 0.9 GO:0015865 purine nucleotide transport(GO:0015865)
0.0 0.6 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 1.3 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.9 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.2 GO:0007207 regulation of vascular smooth muscle contraction(GO:0003056) adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.3 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 1.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 1.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.6 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 1.3 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0 0.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.9 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.3 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 2.2 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 1.8 GO:0006968 cellular defense response(GO:0006968)
0.0 0.7 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.8 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 1.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.3 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.4 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.0 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.6 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0042048 olfactory behavior(GO:0042048)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 21.4 GO:0005579 membrane attack complex(GO:0005579)
2.2 8.9 GO:0071757 hexameric IgM immunoglobulin complex(GO:0071757)
2.0 6.1 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
2.0 7.9 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.1 3.4 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.8 4.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.6 4.0 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.4 2.6 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.3 4.3 GO:0030478 actin cap(GO:0030478)
0.3 2.7 GO:0071953 elastic fiber(GO:0071953)
0.2 5.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.2 1.3 GO:1990357 terminal web(GO:1990357)
0.2 0.6 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.2 2.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 19.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 2.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 2.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 12.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.5 GO:0036398 TCR signalosome(GO:0036398)
0.1 0.7 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 8.4 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 9.1 GO:0005581 collagen trimer(GO:0005581)
0.1 0.3 GO:0071149 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.0 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 4.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.0 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.5 GO:0008091 spectrin(GO:0008091)
0.0 1.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 1.1 GO:1990777 plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0 2.5 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.6 GO:0071141 SMAD protein complex(GO:0071141)
0.0 7.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 2.6 GO:0005604 basement membrane(GO:0005604)
0.0 4.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 3.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 22.4 GO:0005615 extracellular space(GO:0005615)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 7.9 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.5 13.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.3 8.9 GO:0019862 IgA binding(GO:0019862)
1.0 3.0 GO:0005174 CD40 receptor binding(GO:0005174)
1.0 3.0 GO:0035375 zymogen binding(GO:0035375)
1.0 4.8 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.9 2.6 GO:1904854 proteasome core complex binding(GO:1904854)
0.8 2.4 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.8 2.3 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.7 4.0 GO:0004522 ribonuclease A activity(GO:0004522)
0.6 2.5 GO:1902271 D3 vitamins binding(GO:1902271)
0.6 3.7 GO:0035276 ethanol binding(GO:0035276)
0.6 4.8 GO:0035473 lipase binding(GO:0035473)
0.5 3.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 4.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.4 1.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.3 1.0 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.3 2.0 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.3 1.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 1.3 GO:0004948 calcitonin receptor activity(GO:0004948)
0.3 14.9 GO:0042056 chemoattractant activity(GO:0042056)
0.2 1.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2 3.5 GO:0015232 heme transporter activity(GO:0015232)
0.2 0.6 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.2 6.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.7 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.1 0.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.3 GO:0031013 troponin I binding(GO:0031013)
0.1 0.9 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 2.9 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.7 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 3.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 3.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 4.8 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 1.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 1.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 14.4 GO:0008201 heparin binding(GO:0008201)
0.1 0.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.4 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 1.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.9 GO:0015216 purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 4.8 GO:0005507 copper ion binding(GO:0005507)
0.0 0.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.5 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 1.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 2.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.6 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 4.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.7 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.2 GO:0043236 laminin binding(GO:0043236)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.0 GO:0019956 chemokine binding(GO:0019956)
0.0 0.5 GO:0015197 peptide transporter activity(GO:0015197)
0.0 1.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 7.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.0 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 1.2 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 2.5 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 24.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 11.4 PID CD40 PATHWAY CD40/CD40L signaling
0.1 14.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 10.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 6.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 4.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 2.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 3.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 4.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 12.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 9.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 3.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 29.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.6 9.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 12.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 5.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.3 4.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 7.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 3.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 5.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 3.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 2.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 6.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 3.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 4.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.1 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.1 6.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 3.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 2.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 2.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 3.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 2.0 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 4.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 3.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 2.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions