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Illumina Body Map 2 (GSE30611)

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Results for FOXF2_FOXJ1

Z-value: 1.10

Motif logo

Transcription factors associated with FOXF2_FOXJ1

Gene Symbol Gene ID Gene Info
ENSG00000137273.6 forkhead box F2
ENSG00000129654.8 forkhead box J1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXF2hg38_v1_chr6_+_1389553_1389605-0.222.4e-01Click!
FOXJ1hg38_v1_chr17_-_76141240_76141267-0.173.4e-01Click!

Activity profile of FOXF2_FOXJ1 motif

Sorted Z-values of FOXF2_FOXJ1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_74431338 5.53 ENST00000342648.9
ENST00000652232.1
ENST00000481232.2
G protein-coupled receptor class C group 5 member C
chr10_+_122163672 5.23 ENST00000369004.7
ENST00000260733.7
transforming acidic coiled-coil containing protein 2
chr10_+_122163590 5.06 ENST00000368999.5
transforming acidic coiled-coil containing protein 2
chr1_-_161223559 4.89 ENST00000469730.2
ENST00000463273.5
ENST00000464492.5
ENST00000367990.7
ENST00000470459.6
ENST00000463812.1
ENST00000468465.5
apolipoprotein A2
chr10_+_122163426 4.39 ENST00000360561.7
transforming acidic coiled-coil containing protein 2
chr8_+_66432475 4.38 ENST00000415254.5
ENST00000396623.8
alcohol dehydrogenase iron containing 1
chr1_-_56966006 4.12 ENST00000371237.9
complement C8 beta chain
chr1_-_161223408 3.91 ENST00000491350.1
apolipoprotein A2
chr1_-_56966133 3.80 ENST00000535057.5
ENST00000543257.5
complement C8 beta chain
chr14_-_21025490 3.78 ENST00000553442.5
ENST00000555869.5
ENST00000556457.5
ENST00000397844.6
ENST00000554415.5
ENST00000556974.5
ENST00000554419.5
ENST00000298687.9
ENST00000397858.5
ENST00000360463.7
ENST00000350792.7
ENST00000397847.6
NDRG family member 2
chr2_+_127418420 3.68 ENST00000234071.8
ENST00000429925.5
ENST00000442644.5
protein C, inactivator of coagulation factors Va and VIIIa
chr6_-_56843153 3.39 ENST00000361203.7
ENST00000523817.1
dystonin
chr8_-_123653794 3.29 ENST00000684634.1
kelch like family member 38
chr14_-_21025000 3.29 ENST00000554489.5
ENST00000555657.5
ENST00000557274.5
ENST00000555158.5
ENST00000554833.5
ENST00000555384.5
ENST00000556420.5
ENST00000554893.5
ENST00000553503.5
ENST00000555733.5
ENST00000397856.7
ENST00000553867.5
ENST00000556147.6
ENST00000556008.5
ENST00000557182.5
ENST00000554483.5
ENST00000556688.5
ENST00000397853.7
ENST00000556329.6
ENST00000397851.6
ENST00000554143.5
ENST00000555142.5
ENST00000557676.5
ENST00000556924.5
NDRG family member 2
chr12_-_71157872 3.23 ENST00000546561.2
tetraspanin 8
chr2_-_171894227 3.03 ENST00000422440.7
solute carrier family 25 member 12
chr3_-_10505508 2.98 ENST00000643662.1
ENST00000397077.6
ENST00000360273.7
ATPase plasma membrane Ca2+ transporting 2
chr11_+_114060204 2.90 ENST00000683318.1
zinc finger and BTB domain containing 16
chr17_+_69414690 2.88 ENST00000590474.7
mitogen-activated protein kinase kinase 6
chr4_+_99574812 2.84 ENST00000422897.6
ENST00000265517.10
microsomal triglyceride transfer protein
chr4_-_69495897 2.78 ENST00000305107.7
ENST00000639621.1
UDP glucuronosyltransferase family 2 member B4
chr2_-_233013228 2.71 ENST00000264051.8
neuronal guanine nucleotide exchange factor
chr5_+_79689825 2.67 ENST00000446378.3
cardiomyopathy associated 5
chr1_+_226940279 2.67 ENST00000366778.5
ENST00000366777.4
coenzyme Q8A
chr2_+_167135901 2.54 ENST00000628543.2
xin actin binding repeat containing 2
chr4_-_69495861 2.51 ENST00000512583.5
UDP glucuronosyltransferase family 2 member B4
chr6_+_63571702 2.45 ENST00000672924.1
protein tyrosine phosphatase 4A1
chr5_-_42811884 2.33 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr1_-_246566238 2.23 ENST00000366514.5
transcription factor B2, mitochondrial
chr16_+_6019585 2.17 ENST00000547372.5
RNA binding fox-1 homolog 1
chr17_+_35147807 2.15 ENST00000394570.7
ENST00000268876.9
unc-45 myosin chaperone B
chr5_-_142686079 2.11 ENST00000337706.7
fibroblast growth factor 1
chr14_-_74084393 2.04 ENST00000350259.8
ENST00000553458.6
aldehyde dehydrogenase 6 family member A1
chr16_+_6019016 2.04 ENST00000550418.6
RNA binding fox-1 homolog 1
chr20_+_45406560 2.01 ENST00000372717.5
ENST00000360981.8
dysbindin domain containing 2
chr14_+_32495052 1.98 ENST00000556638.1
A-kinase anchoring protein 6
chr11_-_119376271 1.98 ENST00000531070.1
ubiquitin specific peptidase 2
chr4_-_139302460 1.90 ENST00000394223.2
ENST00000676245.1
NADH:ubiquinone oxidoreductase subunit C1
chr5_-_142686047 1.81 ENST00000360966.9
ENST00000411960.1
fibroblast growth factor 1
chr1_-_46665849 1.76 ENST00000532925.5
ENST00000542495.5
ATP synthase mitochondrial F1 complex assembly factor 1
chr5_-_59768631 1.75 ENST00000502575.1
ENST00000507116.5
phosphodiesterase 4D
chr4_-_139302516 1.72 ENST00000394228.5
ENST00000539387.5
NADH:ubiquinone oxidoreductase subunit C1
chr4_-_185535498 1.71 ENST00000284767.12
ENST00000284771.7
ENST00000284770.10
ENST00000620787.5
ENST00000629667.2
PDZ and LIM domain 3
chr2_-_36966471 1.71 ENST00000379213.3
striatin
chrX_+_71215156 1.70 ENST00000374029.2
ENST00000675209.1
ENST00000647424.1
ENST00000675368.1
ENST00000675609.1
ENST00000646835.1
ENST00000447581.2
gap junction protein beta 1
chr2_+_86720282 1.70 ENST00000283632.5
required for meiotic nuclear division 5 homolog A
chr2_-_178702479 1.68 ENST00000414766.5
titin
chr22_-_37109703 1.63 ENST00000406856.7
ENST00000676104.1
transmembrane serine protease 6
chr16_+_6019071 1.58 ENST00000547605.5
ENST00000553186.5
RNA binding fox-1 homolog 1
chr15_-_30991595 1.55 ENST00000435680.6
myotubularin related protein 10
chr11_+_67606894 1.55 ENST00000532303.5
ENST00000532244.5
ENST00000528328.1
ENST00000322776.11
ENST00000529927.5
ENST00000532343.5
ENST00000415352.6
ENST00000533075.5
ENST00000529867.5
ENST00000530638.1
NADH:ubiquinone oxidoreductase core subunit V1
chr4_-_151325488 1.53 ENST00000604030.7
SH3 domain containing 19
chr8_+_119067239 1.52 ENST00000332843.3
collectin subfamily member 10
chr2_+_232662733 1.49 ENST00000410095.5
ENST00000611312.1
EF-hand domain family member D1
chr15_-_30991415 1.46 ENST00000563714.5
myotubularin related protein 10
chr1_+_66330711 1.45 ENST00000528771.5
phosphodiesterase 4B
chr22_-_37109409 1.44 ENST00000406725.6
transmembrane serine protease 6
chr12_-_52949776 1.43 ENST00000548998.5
keratin 8
chr1_+_213988501 1.43 ENST00000261454.8
ENST00000435016.2
prospero homeobox 1
chr14_-_94323324 1.43 ENST00000341584.4
serpin family A member 6
chr2_-_36966503 1.43 ENST00000263918.9
striatin
chr12_+_93677352 1.40 ENST00000552983.5
ENST00000332896.8
ENST00000552033.5
ENST00000548483.5
CASP2 and RIPK1 domain containing adaptor with death domain
chr12_-_52949818 1.40 ENST00000546897.5
ENST00000552551.5
keratin 8
chr3_+_159852933 1.35 ENST00000482804.1
schwannomin interacting protein 1
chr14_-_60724300 1.34 ENST00000556952.3
ENST00000216513.5
SIX homeobox 4
chr15_+_42404866 1.32 ENST00000674041.1
ENST00000565559.5
ENST00000673750.1
ENST00000674135.1
calpain 3
chr11_-_64166102 1.31 ENST00000255681.7
ENST00000675777.1
mono-ADP ribosylhydrolase 1
chr3_+_98732236 1.30 ENST00000265261.10
ENST00000483910.5
ENST00000460774.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr10_-_329480 1.29 ENST00000434695.2
disco interacting protein 2 homolog C
chr14_+_49768109 1.27 ENST00000298307.10
ENST00000554589.5
ENST00000557247.1
kelch domain containing 2
chr20_-_54028692 1.23 ENST00000448484.5
brain enriched myelin associated protein 1
chr15_+_42404820 1.23 ENST00000673839.1
ENST00000673978.1
calpain 3
chr11_-_115504389 1.21 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
cell adhesion molecule 1
chr5_-_36301883 1.21 ENST00000502994.5
ENST00000515759.5
ENST00000296604.8
RAN binding protein 3 like
chr8_+_78516329 1.20 ENST00000396418.7
ENST00000352966.9
cAMP-dependent protein kinase inhibitor alpha
chr19_+_7515292 1.19 ENST00000596712.1
zinc finger protein 358
chr12_+_20810698 1.19 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr15_+_42404842 1.16 ENST00000673928.1
calpain 3
chr17_-_7179348 1.16 ENST00000573083.1
ENST00000574388.5
ENST00000269299.8
asialoglycoprotein receptor 1
chr6_+_101398788 1.14 ENST00000369138.5
ENST00000413795.5
ENST00000358361.7
glutamate ionotropic receptor kainate type subunit 2
chr6_+_36676489 1.14 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chr18_+_34493289 1.14 ENST00000682923.1
ENST00000596745.5
ENST00000283365.14
ENST00000315456.10
ENST00000598774.6
ENST00000684266.1
ENST00000683092.1
ENST00000683379.1
ENST00000684359.1
dystrobrevin alpha
chr2_+_174395721 1.14 ENST00000272732.11
ENST00000458563.5
ENST00000409673.7
ENST00000435964.1
ENST00000424069.5
ENST00000427038.5
secernin 3
chr12_-_71157992 1.13 ENST00000247829.8
tetraspanin 8
chr8_-_69834970 1.13 ENST00000260126.9
solute carrier organic anion transporter family member 5A1
chr14_-_94323389 1.10 ENST00000557225.1
serpin family A member 6
chr4_-_110198976 1.09 ENST00000506625.5
ELOVL fatty acid elongase 6
chr14_+_55661272 1.06 ENST00000555573.5
kinectin 1
chr4_-_151227881 1.06 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr14_+_55661242 1.04 ENST00000553624.5
kinectin 1
chr6_+_63572472 1.02 ENST00000370651.7
ENST00000626021.3
novel protein
protein tyrosine phosphatase 4A1
chrX_+_86714623 1.01 ENST00000484479.1
dachshund family transcription factor 2
chr4_-_110198650 1.01 ENST00000394607.7
ELOVL fatty acid elongase 6
chr11_+_118527463 1.01 ENST00000302783.10
tetratricopeptide repeat domain 36
chr5_+_150660841 1.01 ENST00000297130.4
myozenin 3
chr12_-_52949849 1.00 ENST00000619952.2
ENST00000546826.5
keratin 8
chr3_+_52211442 0.99 ENST00000459884.1
5'-aminolevulinate synthase 1
chr6_+_160702238 0.98 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
plasminogen
chr1_+_185734362 0.91 ENST00000271588.9
hemicentin 1
chr11_-_8717836 0.91 ENST00000531060.1
DENN domain containing 2B
chr9_-_86282061 0.91 ENST00000311534.6
iron-sulfur cluster assembly 1
chr6_-_75493629 0.91 ENST00000393004.6
filamin A interacting protein 1
chr20_+_45407207 0.90 ENST00000372712.6
dysbindin domain containing 2
chr3_-_58537283 0.89 ENST00000459701.6
acyl-CoA oxidase 2
chr17_+_9021501 0.88 ENST00000173229.7
netrin 1
chr3_+_109136707 0.87 ENST00000622536.6
chromosome 3 open reading frame 85
chr4_-_110199173 0.87 ENST00000503885.1
ELOVL fatty acid elongase 6
chr3_-_58537181 0.87 ENST00000302819.10
acyl-CoA oxidase 2
chr1_+_246566513 0.82 ENST00000366511.1
consortin, connexin sorting protein
chr6_-_56851888 0.81 ENST00000312431.10
ENST00000520645.5
dystonin
chr4_+_87832917 0.81 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr6_-_75493773 0.80 ENST00000237172.12
filamin A interacting protein 1
chr18_-_12656716 0.79 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
spire type actin nucleation factor 1
chr11_-_8718018 0.79 ENST00000533020.5
DENN domain containing 2B
chr1_-_24143112 0.78 ENST00000270800.2
interleukin 22 receptor subunit alpha 1
chr18_+_34493386 0.78 ENST00000679936.1
dystrobrevin alpha
chr20_-_22585451 0.78 ENST00000377115.4
forkhead box A2
chr5_+_150661243 0.76 ENST00000517768.6
myozenin 3
chr18_-_54959391 0.75 ENST00000591504.6
coiled-coil domain containing 68
chr9_-_132945372 0.74 ENST00000646440.1
TSC complex subunit 1
chr3_+_189631373 0.74 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chr2_-_239309202 0.74 ENST00000446876.1
histone deacetylase 4
chr10_-_116273009 0.74 ENST00000439649.8
ENST00000369234.5
ENST00000682194.1
ENST00000355422.11
GDNF family receptor alpha 1
chr1_+_65264694 0.73 ENST00000263441.11
ENST00000395325.7
DnaJ heat shock protein family (Hsp40) member C6
chr8_-_71547626 0.73 ENST00000647540.1
ENST00000644229.1
EYA transcriptional coactivator and phosphatase 1
chr11_+_27055215 0.71 ENST00000525090.1
gamma-butyrobetaine hydroxylase 1
chr18_+_57352541 0.71 ENST00000324000.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr6_+_146027662 0.71 ENST00000492807.6
ENST00000361719.6
glutamate metabotropic receptor 1
chr9_-_86282511 0.70 ENST00000375991.9
ENST00000326094.4
iron-sulfur cluster assembly 1
chr7_+_44606619 0.69 ENST00000222673.6
ENST00000444676.5
ENST00000631326.2
oxoglutarate dehydrogenase
chr3_-_58537153 0.69 ENST00000474098.1
acyl-CoA oxidase 2
chr6_-_25830557 0.68 ENST00000468082.1
solute carrier family 17 member 1
chr13_-_61415508 0.68 ENST00000409204.4
protocadherin 20
chr1_-_150010675 0.65 ENST00000417191.2
ENST00000581312.6
OTU deubiquitinase 7B
chr2_-_87021844 0.65 ENST00000355705.4
ENST00000409310.6
plasminogen like B1
chr7_+_12211259 0.65 ENST00000396668.8
ENST00000444443.5
ENST00000396667.7
transmembrane protein 106B
chr1_-_109389886 0.63 ENST00000493736.5
sortilin 1
chr10_+_110225955 0.63 ENST00000239007.11
MAX interactor 1, dimerization protein
chr3_-_186109067 0.63 ENST00000306376.10
ETS variant transcription factor 5
chr7_+_44606563 0.62 ENST00000439616.6
oxoglutarate dehydrogenase
chr12_-_95995920 0.62 ENST00000552509.5
histidine ammonia-lyase
chr19_+_9247344 0.61 ENST00000641946.1
olfactory receptor family 7 subfamily E member 24
chr17_-_8156320 0.61 ENST00000584202.1
ENST00000354903.9
ENST00000577253.5
period circadian regulator 1
chr7_+_44606578 0.61 ENST00000443864.6
ENST00000447398.5
ENST00000449767.5
ENST00000419661.5
oxoglutarate dehydrogenase
chr4_-_21948733 0.61 ENST00000447367.6
ENST00000382152.7
potassium voltage-gated channel interacting protein 4
chr1_+_152514474 0.60 ENST00000368790.4
cysteine rich C-terminal 1
chr1_+_246566422 0.59 ENST00000366513.9
ENST00000366512.7
consortin, connexin sorting protein
chr20_-_63951122 0.59 ENST00000369908.9
uridine-cytidine kinase 1 like 1
chr14_-_60165363 0.59 ENST00000557185.6
dehydrogenase/reductase 7
chr12_-_62935117 0.57 ENST00000228705.7
protein phosphatase, Mg2+/Mn2+ dependent 1H
chr19_+_49877660 0.57 ENST00000535102.6
TBC1 domain family member 17
chr12_-_21775581 0.57 ENST00000537950.1
ENST00000665145.1
potassium inwardly rectifying channel subfamily J member 8
chr6_+_72212802 0.56 ENST00000401910.7
regulating synaptic membrane exocytosis 1
chr10_+_73909147 0.56 ENST00000481390.5
plasminogen activator, urokinase
chr13_-_102401599 0.56 ENST00000376131.8
fibroblast growth factor 14
chr9_+_129141954 0.55 ENST00000432651.5
ENST00000435132.5
protein phosphatase 2 phosphatase activator
chr6_+_43059857 0.55 ENST00000259708.7
ENST00000472792.1
ENST00000479388.5
ENST00000460283.1
ENST00000394056.6
kinesin light chain 4
chrX_+_49162564 0.54 ENST00000616266.4
MAGI family member, X-linked
chr2_+_87748087 0.54 ENST00000359481.9
plasminogen like B2
chr15_+_72686197 0.54 ENST00000268057.9
ENST00000569338.5
Bardet-Biedl syndrome 4
chr19_+_49877694 0.53 ENST00000221543.10
TBC1 domain family member 17
chr9_-_83817632 0.53 ENST00000376365.7
ENST00000376371.7
G kinase anchoring protein 1
chr6_+_97010193 0.53 ENST00000620278.1
kelch like family member 32
chr4_-_175891691 0.52 ENST00000507540.1
glycoprotein M6A
chr14_-_60165293 0.52 ENST00000554101.5
ENST00000557137.1
dehydrogenase/reductase 7
chr1_+_220528333 0.51 ENST00000677505.1
microtubule affinity regulating kinase 1
chr3_+_48918815 0.51 ENST00000452882.5
ENST00000430423.5
ENST00000449376.5
ENST00000356401.9
ENST00000420814.5
ENST00000449729.5
ENST00000433170.5
ariadne RBR E3 ubiquitin protein ligase 2
chr3_+_124384513 0.51 ENST00000682540.1
ENST00000522553.6
ENST00000682695.1
ENST00000682674.1
ENST00000684382.1
kalirin RhoGEF kinase
chr7_+_12211308 0.51 ENST00000442107.1
transmembrane protein 106B
chr8_-_144529048 0.51 ENST00000527462.1
ENST00000313465.5
ENST00000524821.6
chromosome 8 open reading frame 82
chr6_+_43059614 0.51 ENST00000453940.6
ENST00000347162.10
ENST00000479632.5
ENST00000470728.5
ENST00000458460.6
kinesin light chain 4
chr9_+_129142016 0.50 ENST00000434095.2
protein phosphatase 2 phosphatase activator
chr16_+_56191476 0.50 ENST00000262493.12
G protein subunit alpha o1
chr2_-_179746040 0.50 ENST00000409343.5
zinc finger protein 385B
chr10_-_116273606 0.50 ENST00000682743.1
GDNF family receptor alpha 1
chr3_+_187743654 0.50 ENST00000648485.1
BCL6 antisense 1
chr10_+_110226079 0.49 ENST00000393134.5
MAX interactor 1, dimerization protein
chr15_+_72686179 0.48 ENST00000395205.6
Bardet-Biedl syndrome 4
chr6_+_108560906 0.48 ENST00000406360.2
forkhead box O3
chr19_-_49877279 0.48 ENST00000391832.7
ENST00000344175.10
AKT1 substrate 1
chr6_-_160664270 0.47 ENST00000316300.10
lipoprotein(a)
chr5_-_143403611 0.47 ENST00000394464.7
ENST00000231509.7
nuclear receptor subfamily 3 group C member 1
chr1_+_50105666 0.46 ENST00000651347.1
ELAV like RNA binding protein 4
chr5_-_131796921 0.46 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr12_-_95996302 0.46 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
histidine ammonia-lyase
chr12_-_21403637 0.45 ENST00000450590.5
ENST00000453443.5
solute carrier organic anion transporter family member 1A2
chr5_-_151080978 0.45 ENST00000520931.5
ENST00000521591.6
ENST00000520695.5
ENST00000610535.5
ENST00000518977.5
ENST00000389378.6
ENST00000610874.4
TNFAIP3 interacting protein 1
chr4_+_171813397 0.45 ENST00000506823.6
polypeptide N-acetylgalactosaminyltransferase like 6
chr6_-_160258814 0.45 ENST00000366953.8
solute carrier family 22 member 2
chr9_+_129141637 0.45 ENST00000419582.5
protein phosphatase 2 phosphatase activator
chrX_-_108736556 0.45 ENST00000372129.4
insulin receptor substrate 4
chr14_-_100903696 0.44 ENST00000649591.1
retrotransposon Gag like 1
chr12_-_55958582 0.44 ENST00000549404.5
premelanosome protein
chr7_+_143183419 0.44 ENST00000446620.1
taste 2 receptor member 39
chr12_+_49741565 0.44 ENST00000549445.5
ENST00000550951.5
ENST00000549385.5
ENST00000548713.5
ENST00000548201.5
transmembrane BAX inhibitor motif containing 6
chr3_-_38816217 0.43 ENST00000449082.3
ENST00000655275.1
sodium voltage-gated channel alpha subunit 10
chr6_+_83853576 0.41 ENST00000369687.2
ripply transcriptional repressor 2
chr12_-_62191422 0.41 ENST00000551449.1
TAFA chemokine like family member 2
chr17_-_41786688 0.40 ENST00000310706.9
ENST00000393931.8
ENST00000424457.5
ENST00000591690.5
junction plakoglobin
chr7_+_116953238 0.40 ENST00000393446.6
suppression of tumorigenicity 7

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXF2_FOXJ1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.8 GO:0060621 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
1.8 5.3 GO:0006711 estrogen catabolic process(GO:0006711)
1.5 4.4 GO:0015993 molecular hydrogen transport(GO:0015993)
1.0 3.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.9 3.7 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.7 2.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.6 2.9 GO:0072709 cellular response to sorbitol(GO:0072709)
0.5 2.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.5 2.9 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.5 1.4 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.4 1.3 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.4 1.9 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.4 1.1 GO:0006407 rRNA export from nucleus(GO:0006407)
0.4 7.1 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.4 3.7 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.3 3.5 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.3 1.8 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.3 2.8 GO:0034378 chylomicron assembly(GO:0034378)
0.2 1.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919) interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 1.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 3.8 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.2 2.0 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 3.0 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 1.7 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.2 4.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 3.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 0.8 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2 2.7 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.2 3.1 GO:0097264 self proteolysis(GO:0097264)
0.2 4.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.2 0.7 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 2.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 0.6 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.2 0.5 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 1.1 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 1.5 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.1 1.0 GO:0050893 sensory processing(GO:0050893)
0.1 0.6 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 1.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 1.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 0.4 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 1.4 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.1 0.8 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.8 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 2.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.3 GO:0036245 cellular response to menadione(GO:0036245)
0.1 0.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.7 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.1 0.9 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.4 GO:1900190 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1 2.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 2.7 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.3 GO:0045175 basal protein localization(GO:0045175)
0.1 1.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.7 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.4 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.2 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1 0.8 GO:0036089 cleavage furrow formation(GO:0036089) formin-nucleated actin cable assembly(GO:0070649)
0.1 0.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 1.7 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.7 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 2.6 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.3 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1 0.4 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.1 1.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 2.5 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 0.2 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.1 0.5 GO:0044211 CTP salvage(GO:0044211)
0.1 0.6 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 1.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.4 GO:0008218 bioluminescence(GO:0008218)
0.1 5.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.2 GO:1903487 regulation of lactation(GO:1903487)
0.1 2.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 5.2 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 1.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 4.4 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 1.0 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 1.0 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 12.8 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.4 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.0 0.4 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 1.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:1900108 growth plate cartilage chondrocyte proliferation(GO:0003419) negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.7 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.2 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.3 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.7 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.6 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.3 GO:1902617 response to fluoride(GO:1902617)
0.0 0.5 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.4 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.4 GO:1901374 acetate ester transport(GO:1901374)
0.0 0.3 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 1.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 1.1 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 1.3 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 3.0 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.5 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0021756 striatum development(GO:0021756)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 2.7 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.2 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 2.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 1.0 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.3 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 1.8 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.3 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.7 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 1.1 GO:0003281 ventricular septum development(GO:0003281)
0.0 0.1 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 1.1 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0042438 melanin biosynthetic process(GO:0042438)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.9 GO:0005579 membrane attack complex(GO:0005579)
0.6 1.7 GO:0034657 GID complex(GO:0034657)
0.5 4.6 GO:0031673 H zone(GO:0031673)
0.5 8.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 1.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 1.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 0.7 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.2 1.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 1.0 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.4 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 2.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 2.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 3.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 4.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.2 GO:0036457 keratohyalin granule(GO:0036457)
0.1 1.0 GO:0034464 BBSome(GO:0034464)
0.1 1.7 GO:0005922 connexon complex(GO:0005922)
0.1 4.4 GO:0031430 M band(GO:0031430)
0.1 4.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 11.9 GO:0030018 Z disc(GO:0030018)
0.0 0.7 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0070701 mucus layer(GO:0070701)
0.0 3.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 2.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.2 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 10.4 GO:0030426 growth cone(GO:0030426)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 7.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 8.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 10.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.0 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.9 GO:0042383 sarcolemma(GO:0042383)
0.0 1.3 GO:0005776 autophagosome(GO:0005776)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 8.8 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.8 2.4 GO:0033791 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity(GO:0033791)
0.6 1.9 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.5 3.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.3 4.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.3 1.0 GO:1904854 proteasome core complex binding(GO:1904854)
0.3 2.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 1.3 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2 1.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 1.8 GO:0051373 FATZ binding(GO:0051373)
0.2 3.0 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.0 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.2 1.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 0.7 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.6 GO:0030379 neurotensin receptor activity, non-G-protein coupled(GO:0030379)
0.2 1.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 1.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 1.7 GO:0031433 telethonin binding(GO:0031433)
0.1 0.4 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 3.7 GO:0031432 titin binding(GO:0031432)
0.1 1.4 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.4 GO:0071253 connexin binding(GO:0071253)
0.1 1.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 3.9 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.5 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 1.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 5.3 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.4 GO:0008513 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.1 2.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 2.2 GO:0008430 selenium binding(GO:0008430)
0.1 3.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.7 GO:0005243 gap junction channel activity(GO:0005243)
0.1 4.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.4 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.6 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.8 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.7 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 3.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 5.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.7 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 2.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.7 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 1.5 GO:0005537 mannose binding(GO:0005537)
0.1 1.4 GO:0070513 death domain binding(GO:0070513)
0.1 1.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 1.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 2.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 3.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.3 GO:1902444 riboflavin binding(GO:1902444)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.7 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 1.0 GO:0034452 dynactin binding(GO:0034452)
0.0 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.0 13.5 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 2.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 1.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 3.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 2.0 GO:0030332 cyclin binding(GO:0030332)
0.0 0.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 1.9 GO:0043531 ADP binding(GO:0043531)
0.0 2.8 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 3.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 2.5 GO:0005496 steroid binding(GO:0005496)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015) BMP binding(GO:0036122)
0.0 1.3 GO:0019894 kinesin binding(GO:0019894)
0.0 1.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 5.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 6.0 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 2.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.9 GO:0002039 p53 binding(GO:0002039)
0.0 1.3 GO:0019213 deacetylase activity(GO:0019213)
0.0 1.1 GO:0031490 chromatin DNA binding(GO:0031490)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 4.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 2.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 5.9 PID FGF PATHWAY FGF signaling pathway
0.0 4.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 3.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 5.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.7 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 11.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 3.9 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.2 3.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 5.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.9 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 4.1 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.1 4.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 6.3 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1 3.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.9 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 3.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 5.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.4 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 1.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 3.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 3.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 3.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 3.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.1 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 1.3 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling