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Illumina Body Map 2 (GSE30611)

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Results for FOXQ1

Z-value: 1.21

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Transcription factors associated with FOXQ1

Gene Symbol Gene ID Gene Info
ENSG00000164379.7 forkhead box Q1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXQ1hg38_v1_chr6_+_1312090_13121050.067.5e-01Click!

Activity profile of FOXQ1 motif

Sorted Z-values of FOXQ1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_52803807 3.74 ENST00000334575.6
glutathione S-transferase alpha 1
chr6_-_52909666 2.85 ENST00000370968.5
ENST00000211122.4
glutathione S-transferase alpha 3
chr20_+_33217325 2.66 ENST00000375452.3
ENST00000375454.8
BPI fold containing family A member 3
chr6_-_52763473 2.58 ENST00000493422.3
glutathione S-transferase alpha 2
chr4_+_154563003 2.42 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chrX_+_105948429 2.17 ENST00000540278.1
Nik related kinase
chr6_+_131637296 2.15 ENST00000358229.6
ENST00000357639.8
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr7_-_41703062 2.14 ENST00000242208.5
inhibin subunit beta A
chrX_+_107777733 2.01 ENST00000509000.3
nuclear cap binding protein subunit 2 like
chr14_+_21030201 1.98 ENST00000321760.11
ENST00000460647.6
ENST00000530140.6
ENST00000472458.5
tubulin polymerization promoting protein family member 2
chr6_-_87095059 1.95 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr6_-_49744378 1.92 ENST00000371159.8
ENST00000263045.9
cysteine rich secretory protein 3
chr3_+_107377433 1.89 ENST00000261058.3
coiled-coil domain containing 54
chrX_-_55182442 1.83 ENST00000545075.3
MT-RNR2 like 10
chrX_+_111876177 1.73 ENST00000635763.2
TRPC5 opposite strand
chr6_-_49744434 1.72 ENST00000433368.6
ENST00000354620.4
cysteine rich secretory protein 3
chr1_+_196819731 1.65 ENST00000320493.10
ENST00000367424.4
complement factor H related 1
chr1_-_237945275 1.52 ENST00000604646.1
MT-RNR2 like 11
chr9_-_114074969 1.51 ENST00000466610.6
alpha-1-microglobulin/bikunin precursor
chr3_+_171843337 1.49 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
transmembrane protein 212
chr11_+_73950985 1.49 ENST00000339764.6
DnaJ heat shock protein family (Hsp40) member B13
chr11_+_7088991 1.46 ENST00000306904.7
RBMX like 2
chr9_-_95317671 1.45 ENST00000490972.7
ENST00000647778.1
ENST00000649611.1
ENST00000289081.8
FA complementation group C
chrX_+_9912434 1.45 ENST00000418909.6
shroom family member 2
chr11_-_26572102 1.41 ENST00000455601.6
mucin 15, cell surface associated
chr7_-_122702912 1.41 ENST00000447240.1
ENST00000434824.2
ring finger protein 148
chr8_-_48921419 1.39 ENST00000020945.4
snail family transcriptional repressor 2
chrX_+_108044967 1.38 ENST00000415430.7
V-set and immunoglobulin domain containing 1
chr17_+_9576627 1.36 ENST00000396219.7
ENST00000352665.10
cilia and flagella associated protein 52
chr7_+_128709052 1.36 ENST00000485070.5
family with sequence similarity 71 member F1
chrX_+_111876051 1.34 ENST00000612026.5
TRPC5 opposite strand
chr4_-_118352967 1.32 ENST00000296498.3
serine protease 12
chrX_+_108045050 1.31 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr7_-_122699108 1.31 ENST00000340112.3
ring finger protein 133
chr15_+_50182188 1.26 ENST00000267842.10
solute carrier family 27 member 2
chr10_+_125973373 1.26 ENST00000417114.5
ENST00000445510.5
ENST00000368691.5
fibronectin type III and ankyrin repeat domains 1
chr3_-_57199938 1.26 ENST00000473921.2
ENST00000295934.8
HESX homeobox 1
chr1_+_197912462 1.25 ENST00000475727.1
ENST00000367391.5
ENST00000367390.7
LIM homeobox 9
chr1_+_196943738 1.25 ENST00000367415.8
ENST00000367421.5
ENST00000649283.1
ENST00000476712.6
ENST00000496448.6
ENST00000473386.1
ENST00000649960.1
complement factor H related 2
chr15_+_50182215 1.23 ENST00000380902.8
solute carrier family 27 member 2
chr12_-_10884244 1.20 ENST00000543626.4
proline rich protein HaeIII subfamily 1
chr11_-_26572254 1.19 ENST00000529533.6
mucin 15, cell surface associated
chr15_+_75195613 1.18 ENST00000563905.5
chromosome 15 open reading frame 39
chr3_+_88338451 1.18 ENST00000637986.2
casein kinase 2 subunit alpha' interacting protein
chr2_+_79025678 1.18 ENST00000393897.6
regenerating family member 3 gamma
chr2_+_79025696 1.16 ENST00000272324.10
regenerating family member 3 gamma
chr12_-_91180365 1.16 ENST00000547937.5
decorin
chr1_+_151766655 1.16 ENST00000400999.7
ornithine decarboxylase antizyme 3
chr11_-_26572130 1.15 ENST00000527569.1
mucin 15, cell surface associated
chr1_-_75932392 1.14 ENST00000284142.7
ankyrin repeat and SOCS box containing 17
chr3_-_173141227 1.14 ENST00000351008.4
spermatogenesis associated 16
chr9_+_69820827 1.13 ENST00000527647.5
ENST00000480564.1
chromosome 9 open reading frame 135
chr4_+_122378966 1.12 ENST00000446706.5
ENST00000296513.7
adenosine deaminase domain containing 1
chr6_+_31137646 1.10 ENST00000547221.1
psoriasis susceptibility 1 candidate 1
chr10_-_96271553 1.07 ENST00000224337.10
B cell linker
chr16_+_4734519 1.07 ENST00000299320.10
chromosome 16 open reading frame 71
chr10_-_11532275 1.07 ENST00000277575.5
USP6 N-terminal like
chr12_-_91111460 1.05 ENST00000266718.5
lumican
chr14_+_77377115 1.05 ENST00000216471.4
sterile alpha motif domain containing 15
chr16_+_4734457 1.05 ENST00000590191.1
chromosome 16 open reading frame 71
chr19_+_49930219 1.04 ENST00000596658.1
activating transcription factor 5
chr6_-_49866527 1.03 ENST00000335847.9
cysteine rich secretory protein 1
chr20_+_13008919 1.03 ENST00000399002.7
ENST00000434210.5
serine palmitoyltransferase long chain base subunit 3
chr9_+_69820799 1.03 ENST00000377197.8
chromosome 9 open reading frame 135
chr4_+_122379437 1.03 ENST00000439307.5
ENST00000388724.6
adenosine deaminase domain containing 1
chr17_-_66220630 1.02 ENST00000585162.1
apolipoprotein H
chr4_+_70334963 1.02 ENST00000273936.6
calcium binding protein, spermatid associated 1
chr9_+_122159886 1.01 ENST00000373764.8
ENST00000536616.5
MORN repeat containing 5
chr10_+_15043937 1.01 ENST00000378228.8
ENST00000378217.3
oleoyl-ACP hydrolase
chr3_+_186666003 1.01 ENST00000232003.5
histidine rich glycoprotein
chr11_-_85686123 1.00 ENST00000316398.5
coiled-coil domain containing 89
chr1_-_159714581 0.99 ENST00000255030.9
ENST00000437342.1
ENST00000368112.5
ENST00000368111.5
ENST00000368110.1
C-reactive protein
chr9_-_34895722 0.99 ENST00000603640.6
ENST00000603592.1
ENST00000340783.11
family with sequence similarity 205 member C
chr4_+_122379508 0.98 ENST00000388725.2
adenosine deaminase domain containing 1
chrX_+_30243715 0.98 ENST00000378981.8
ENST00000397550.6
MAGE family member B1
chr12_-_9999176 0.97 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chrX_+_9912548 0.97 ENST00000452575.1
shroom family member 2
chr9_-_97938157 0.97 ENST00000616898.2
hemogen
chr6_-_49866453 0.96 ENST00000507853.5
cysteine rich secretory protein 1
chr1_+_103655760 0.95 ENST00000370083.9
amylase alpha 1A
chr10_-_96271508 0.95 ENST00000427367.6
ENST00000413476.6
ENST00000371176.6
B cell linker
chr14_-_22819721 0.95 ENST00000554517.5
ENST00000285850.11
ENST00000397529.6
ENST00000555702.5
solute carrier family 7 member 7
chr16_+_4734278 0.94 ENST00000586724.5
chromosome 16 open reading frame 71
chr15_-_58014097 0.94 ENST00000559517.5
aldehyde dehydrogenase 1 family member A2
chr9_+_114323098 0.94 ENST00000259396.9
orosomucoid 1
chr11_+_86395166 0.93 ENST00000528728.1
coiled-coil domain containing 81
chr2_+_200440649 0.92 ENST00000366118.2
spermatogenesis associated serine rich 2 like
chr19_-_32869741 0.91 ENST00000590341.5
ENST00000587772.1
ENST00000023064.9
solute carrier family 7 member 9
chr20_-_57359491 0.90 ENST00000543500.3
MT-RNR2 like 3
chr6_-_116060859 0.89 ENST00000606080.2
fyn related Src family tyrosine kinase
chr12_-_102197827 0.89 ENST00000329406.5
pro-melanin concentrating hormone
chr3_-_134250831 0.89 ENST00000623711.4
receptor like tyrosine kinase
chr7_+_130207847 0.89 ENST00000297819.4
serine rich single-pass membrane protein 1
chr12_-_101739426 0.89 ENST00000266743.6
ENST00000392924.2
ENST00000392927.7
synaptonemal complex protein 3
chr3_-_19934189 0.88 ENST00000295824.14
EF-hand domain family member B
chr17_-_17582417 0.88 ENST00000395783.5
phosphatidylethanolamine N-methyltransferase
chr22_+_30356620 0.87 ENST00000399824.6
ENST00000405659.5
coiled-coil domain containing 157
chr14_+_94581880 0.87 ENST00000557598.1
ENST00000556064.1
serpin family A member 5
chr4_-_184217854 0.86 ENST00000296741.7
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr2_-_187554351 0.85 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
tissue factor pathway inhibitor
chr19_-_4338786 0.85 ENST00000601482.1
ENST00000600324.5
ENST00000594605.6
signal transducing adaptor family member 2
chr7_-_73578657 0.85 ENST00000479892.5
transducin beta like 2
chr6_-_32666648 0.84 ENST00000399082.7
ENST00000399079.7
ENST00000374943.8
ENST00000434651.6
major histocompatibility complex, class II, DQ beta 1
chr14_+_75632610 0.82 ENST00000555027.1
FLVCR heme transporter 2
chr2_+_79025709 0.82 ENST00000409471.1
regenerating family member 3 gamma
chr2_-_105438503 0.82 ENST00000393352.7
ENST00000607522.1
four and a half LIM domains 2
chr2_+_196713117 0.81 ENST00000409270.5
coiled-coil domain containing 150
chr8_-_48921735 0.81 ENST00000396822.6
snail family transcriptional repressor 2
chr1_+_248197265 0.80 ENST00000641626.1
olfactory receptor family 2 subfamily M member 3
chr9_-_72060605 0.79 ENST00000377024.8
ENST00000651200.2
ENST00000652752.1
chromosome 9 open reading frame 57
chr11_+_58943249 0.78 ENST00000300079.9
glycine-N-acyltransferase like 1
chr1_+_103749898 0.78 ENST00000622339.5
amylase alpha 1C
chr9_-_121050264 0.77 ENST00000223642.3
complement C5
chr11_+_102112445 0.77 ENST00000524575.5
Yes1 associated transcriptional regulator
chr4_-_139280179 0.77 ENST00000398955.2
mitochondria localized glutamic acid rich protein
chr5_+_122129533 0.77 ENST00000296600.5
ENST00000504912.1
ENST00000505843.1
zinc finger protein 474
chr18_-_33136075 0.76 ENST00000581852.5
coiled-coil domain containing 178
chrX_+_139530730 0.76 ENST00000218099.7
coagulation factor IX
chr3_-_167474026 0.75 ENST00000466903.1
ENST00000264677.8
serpin family I member 2
chr11_+_60396435 0.75 ENST00000395005.6
membrane spanning 4-domains A14
chrX_+_88747225 0.73 ENST00000276127.9
ENST00000373111.5
CPX chromosome region candidate 1
chr2_-_156342348 0.72 ENST00000409572.5
nuclear receptor subfamily 4 group A member 2
chr2_-_179746040 0.72 ENST00000409343.5
zinc finger protein 385B
chr4_+_74308463 0.72 ENST00000413830.6
epithelial mitogen
chr10_-_73358853 0.72 ENST00000355577.8
ENST00000310715.7
cilia and flagella associated protein 70
chr14_+_104801082 0.72 ENST00000342537.8
zinc finger and BTB domain containing 42
chr13_-_38990824 0.71 ENST00000379631.9
stomatin like 3
chr12_+_19205294 0.71 ENST00000424268.5
pleckstrin homology domain containing A5
chr5_+_38403535 0.71 ENST00000336740.10
ENST00000397202.6
EGF like, fibronectin type III and laminin G domains
chr12_+_7304284 0.71 ENST00000399422.4
acyl-CoA synthetase medium chain family member 4
chr12_-_50396601 0.70 ENST00000327337.6
ENST00000543111.5
family with sequence similarity 186 member A
chr10_-_62236112 0.70 ENST00000315289.6
rhotekin 2
chrX_-_70908705 0.69 ENST00000374333.7
ENST00000395889.6
testis expressed 11
chr14_+_96482982 0.69 ENST00000554706.1
adenylate kinase 7
chr1_+_196977550 0.68 ENST00000256785.5
complement factor H related 5
chr12_-_120325936 0.68 ENST00000549767.1
phospholipase A2 group IB
chr5_+_73626158 0.67 ENST00000296794.10
ENST00000545377.5
ENST00000509848.5
ENST00000513042.7
Rho guanine nucleotide exchange factor 28
chr2_-_224569782 0.67 ENST00000409096.5
cullin 3
chrX_+_139530752 0.67 ENST00000394090.2
coagulation factor IX
chr15_-_51243011 0.66 ENST00000405913.7
ENST00000559878.5
cytochrome P450 family 19 subfamily A member 1
chr6_-_28587250 0.66 ENST00000452236.3
zinc finger BED-type containing 9
chr3_-_49029378 0.66 ENST00000442157.2
ENST00000326739.9
ENST00000677010.1
ENST00000678724.1
ENST00000429182.6
inosine monophosphate dehydrogenase 2
chrX_-_100636799 0.65 ENST00000373020.9
tetraspanin 6
chr13_-_38990856 0.65 ENST00000423210.1
stomatin like 3
chr2_+_21137468 0.65 ENST00000622654.1
tudor domain containing 15
chr11_+_22666604 0.65 ENST00000454584.6
growth arrest specific 2
chr6_+_38715288 0.65 ENST00000327475.11
dynein axonemal heavy chain 8
chr4_-_110199173 0.64 ENST00000503885.1
ELOVL fatty acid elongase 6
chr1_+_172452885 0.64 ENST00000367725.4
chromosome 1 open reading frame 105
chr10_+_5048748 0.64 ENST00000602997.5
ENST00000439082.7
aldo-keto reductase family 1 member C3
chr7_+_1232865 0.64 ENST00000316333.9
UNC homeobox
chr4_-_110198976 0.64 ENST00000506625.5
ELOVL fatty acid elongase 6
chr4_-_110198650 0.63 ENST00000394607.7
ELOVL fatty acid elongase 6
chr3_+_184812385 0.63 ENST00000453056.5
VPS8 subunit of CORVET complex
chr6_-_25830557 0.63 ENST00000468082.1
solute carrier family 17 member 1
chr15_-_56465130 0.63 ENST00000260453.4
meiosis specific nuclear structural 1
chrX_-_143721423 0.62 ENST00000598475.1
SPANX family member N2
chr2_+_142877653 0.62 ENST00000375773.6
ENST00000409512.5
ENST00000264170.9
ENST00000410015.6
kynureninase
chr3_-_57544324 0.61 ENST00000495027.5
ENST00000351747.6
ENST00000389536.8
ENST00000311202.7
dynein axonemal heavy chain 12
chr19_+_14028148 0.61 ENST00000431365.3
ENST00000585987.1
relaxin 3
chr13_-_99258366 0.61 ENST00000397470.5
ENST00000397473.7
G protein-coupled receptor 18
chr10_-_72954790 0.60 ENST00000373032.4
phospholipase A2 group XIIB
chr6_+_135851681 0.60 ENST00000308191.11
phosphodiesterase 7B
chr6_-_29005313 0.60 ENST00000377179.4
zinc finger protein 311
chr16_+_77199408 0.60 ENST00000378644.5
synaptonemal complex central element protein 1 like
chr1_-_56579555 0.58 ENST00000371250.4
phospholipid phosphatase 3
chr10_+_94762673 0.57 ENST00000480405.2
ENST00000371321.9
cytochrome P450 family 2 subfamily C member 19
chr6_-_134950081 0.57 ENST00000367847.2
ENST00000265605.7
ENST00000367845.6
aldehyde dehydrogenase 8 family member A1
chr19_-_58353482 0.56 ENST00000263100.8
alpha-1-B glycoprotein
chr8_-_11996310 0.56 ENST00000526438.5
ENST00000382205.4
defensin beta 134
chr3_+_194136138 0.56 ENST00000232424.4
hes family bHLH transcription factor 1
chr17_-_48613468 0.56 ENST00000498634.2
homeobox B8
chr20_+_31739260 0.55 ENST00000340513.4
ENST00000300403.11
TPX2 microtubule nucleation factor
chrX_-_13319952 0.55 ENST00000622204.1
ENST00000380622.5
ataxin 3 like
chr10_+_35195843 0.55 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr14_-_76826229 0.54 ENST00000557497.1
angel homolog 1
chrX_+_630789 0.54 ENST00000381575.6
short stature homeobox
chr5_+_73813518 0.54 ENST00000296799.8
Rho guanine nucleotide exchange factor 28
chr4_+_95051671 0.54 ENST00000440890.7
bone morphogenetic protein receptor type 1B
chr10_+_99782628 0.53 ENST00000648689.1
ENST00000647814.1
ATP binding cassette subfamily C member 2
chr12_+_19205257 0.53 ENST00000538305.5
pleckstrin homology domain containing A5
chr4_-_69760610 0.53 ENST00000310613.8
sulfotransferase family 1B member 1
chr6_+_147508645 0.53 ENST00000367474.2
sterile alpha motif domain containing 5
chr17_-_35930727 0.53 ENST00000616596.4
ENST00000612980.4
ENST00000613308.4
ENST00000619876.4
RAD52 motif containing 1
chr17_-_40417873 0.52 ENST00000423485.6
DNA topoisomerase II alpha
chr20_-_63956382 0.52 ENST00000358711.7
ENST00000354216.11
uridine-cytidine kinase 1 like 1
chr16_-_65072207 0.52 ENST00000562882.5
ENST00000567934.5
cadherin 11
chr10_-_52772763 0.52 ENST00000675947.1
ENST00000674931.1
mannose binding lectin 2
chr9_-_35812142 0.52 ENST00000497810.1
ENST00000484764.5
sperm associated antigen 8
chr7_+_127887912 0.51 ENST00000486037.1
staphylococcal nuclease and tudor domain containing 1
chr10_+_21524670 0.51 ENST00000631589.1
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr17_-_41140487 0.51 ENST00000345847.4
keratin associated protein 4-6
chr9_-_35563867 0.51 ENST00000399742.7
ENST00000619051.4
family with sequence similarity 166 member B
chr1_-_53940100 0.51 ENST00000371376.1
heat shock protein family B (small) member 11
chr5_-_111756245 0.50 ENST00000447165.6
neuronal regeneration related protein
chr4_-_80073170 0.50 ENST00000403729.7
ANTXR cell adhesion molecule 2
chr12_-_54188871 0.50 ENST00000504338.5
ENST00000514685.5
ENST00000504797.1
ENST00000513838.5
ENST00000505128.5
ENST00000337581.7
ENST00000503306.5
ENST00000243112.9
ENST00000514196.5
ENST00000682136.1
ENST00000506169.5
ENST00000507904.5
ENST00000508394.6
single-strand-selective monofunctional uracil-DNA glycosylase 1
chr2_+_234050679 0.50 ENST00000373368.5
ENST00000168148.8
secreted phosphoprotein 2
chr10_+_15043919 0.50 ENST00000378225.5
oleoyl-ACP hydrolase
chr12_+_106357729 0.50 ENST00000228347.9
RNA polymerase III subunit B

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXQ1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.8 2.4 GO:0008057 eye pigment granule organization(GO:0008057)
0.7 2.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.7 2.2 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.7 2.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.7 2.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.6 2.5 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.5 1.5 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.4 1.3 GO:0035262 gonad morphogenesis(GO:0035262)
0.4 1.2 GO:0015847 putrescine transport(GO:0015847)
0.4 1.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3 0.6 GO:2000974 inhibition of neuroepithelial cell differentiation(GO:0002085) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.3 0.8 GO:0046247 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.3 9.2 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.3 1.6 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 1.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.3 1.0 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.2 2.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 0.5 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 0.6 GO:0016487 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.2 0.6 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 2.9 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.2 0.6 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 0.7 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 0.5 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.2 2.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 0.8 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 1.2 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 2.1 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.9 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.9 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.7 GO:0006311 meiotic gene conversion(GO:0006311)
0.1 0.7 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.5 GO:0061055 myotome development(GO:0061055)
0.1 0.4 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.1 1.5 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.3 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 0.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.9 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.1 0.8 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.9 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.5 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) regulation of melanosome transport(GO:1902908)
0.1 0.9 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.9 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 2.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.5 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.5 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 1.0 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 1.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 0.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 1.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:0001554 luteolysis(GO:0001554)
0.1 0.6 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 0.6 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.4 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 1.4 GO:0030916 otic vesicle formation(GO:0030916)
0.1 2.0 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 0.2 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 2.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.3 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.1 1.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.9 GO:0019695 choline metabolic process(GO:0019695)
0.1 1.0 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.9 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.1 1.9 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.5 GO:0044211 CTP salvage(GO:0044211)
0.1 0.5 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.8 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 0.3 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.4 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 0.4 GO:0010157 response to chlorate(GO:0010157)
0.1 0.5 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.8 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.3 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 1.0 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 1.1 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.8 GO:0015886 heme transport(GO:0015886)
0.0 1.0 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.6 GO:0008354 germ cell migration(GO:0008354)
0.0 0.2 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.4 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.3 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.4 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 0.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 2.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.4 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 3.7 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.7 GO:0015074 DNA integration(GO:0015074)
0.0 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.6 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.2 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.7 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0 0.8 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.5 GO:0045008 depyrimidination(GO:0045008)
0.0 0.2 GO:0009624 response to nematode(GO:0009624)
0.0 0.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.5 GO:1901374 acetate ester transport(GO:1901374)
0.0 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0000820 regulation of glutamine family amino acid metabolic process(GO:0000820)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.4 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.4 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.4 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.6 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 1.3 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.2 GO:0070836 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.4 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.0 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.6 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 2.9 GO:0007286 spermatid development(GO:0007286)
0.0 0.2 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:1990168 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.0 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.0 0.3 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.6 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.7 GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response(GO:0002381)
0.0 0.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 2.0 GO:0005846 nuclear cap binding complex(GO:0005846)
0.2 0.9 GO:0097182 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.2 2.4 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.8 GO:0071149 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.0 GO:0005827 polar microtubule(GO:0005827)
0.1 0.7 GO:0000801 central element(GO:0000801)
0.1 1.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.8 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 1.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.8 GO:0030891 VCB complex(GO:0030891)
0.1 2.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.7 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 7.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 4.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.9 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0044194 cytolytic granule(GO:0044194)
0.0 1.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.5 GO:0097433 dense body(GO:0097433)
0.0 0.5 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 1.0 GO:0036019 endolysosome(GO:0036019)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290) translation initiation ternary complex(GO:0044207)
0.0 0.6 GO:0043203 axon hillock(GO:0043203)
0.0 0.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.5 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.2 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0000346 transcription export complex(GO:0000346)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 2.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0030286 dynein complex(GO:0030286)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 3.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.8 GO:0031430 M band(GO:0031430)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.4 1.2 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.3 1.3 GO:0033265 choline binding(GO:0033265)
0.3 1.5 GO:0016295 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.3 0.9 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.3 1.0 GO:0031208 POZ domain binding(GO:0031208)
0.2 2.1 GO:0034711 inhibin binding(GO:0034711)
0.2 1.5 GO:0019862 IgA binding(GO:0019862)
0.2 0.6 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.2 0.8 GO:0047946 glutamine N-acyltransferase activity(GO:0047946)
0.2 0.5 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 1.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 3.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 0.5 GO:0072545 tyrosine binding(GO:0072545)
0.2 9.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 0.8 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 2.1 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 2.5 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 2.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.6 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.5 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.1 3.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.4 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1 0.6 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.9 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.5 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 0.6 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.3 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.7 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 1.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.9 GO:0032190 acrosin binding(GO:0032190)
0.1 2.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.7 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.9 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 1.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.4 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 1.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.9 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 1.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.2 GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity(GO:0003860)
0.1 0.4 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.1 0.8 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.9 GO:0005537 mannose binding(GO:0005537)
0.0 1.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 1.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.5 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 1.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.8 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.6 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.3 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 2.9 GO:0051087 chaperone binding(GO:0051087)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 2.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0008184 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 1.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 3.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0043125 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) ErbB-3 class receptor binding(GO:0043125)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 2.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 7.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.5 PID BMP PATHWAY BMP receptor signaling
0.0 1.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 2.2 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 2.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 6.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.0 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 9.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 2.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 3.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.5 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 1.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 2.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME SIGNALLING BY NGF Genes involved in Signalling by NGF