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Illumina Body Map 2 (GSE30611)

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Results for GATA6

Z-value: 1.23

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Transcription factors associated with GATA6

Gene Symbol Gene ID Gene Info
GATA6
ENSG00000141448.11 GATA binding protein 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA6hg38_v1_chr18_+_22169580_22169596-0.029.3e-01Click!

Activity profile of GATA6 motif

Sorted Z-values of GATA6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_102311502 5.85 ENST00000404917.6
ENST00000410040.5
IL1RL1
IL18R1
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr10_-_97771954 5.19 ENST00000266066.4
SFRP5
secreted frizzled related protein 5
chr13_-_46142834 4.56 ENST00000674665.1
LCP1
lymphocyte cytosolic protein 1
chr2_+_102311546 4.15 ENST00000233954.6
ENST00000447231.5
IL1RL1
interleukin 1 receptor like 1
chr12_-_54295748 3.82 ENST00000540264.2
ENST00000312156.8
NFE2
nuclear factor, erythroid 2
chr11_-_116837586 3.67 ENST00000375320.5
ENST00000359492.6
ENST00000375329.6
ENST00000375323.5
ENST00000236850.5
APOA1
apolipoprotein A1
chr7_-_100641507 3.66 ENST00000431692.5
ENST00000223051.8
TFR2
transferrin receptor 2
chr9_-_114930508 3.51 ENST00000223795.3
ENST00000618336.4
TNFSF8
TNF superfamily member 8
chr17_+_4771878 3.48 ENST00000270560.4
TM4SF5
transmembrane 4 L six family member 5
chr1_-_167518583 3.29 ENST00000392122.3
CD247
CD247 molecule
chr12_-_9999176 3.05 ENST00000298527.10
ENST00000348658.4
CLEC1B
C-type lectin domain family 1 member B
chr1_-_26913964 3.03 ENST00000254227.4
NR0B2
nuclear receptor subfamily 0 group B member 2
chr1_-_167518521 2.95 ENST00000362089.10
CD247
CD247 molecule
chr19_+_7677082 2.87 ENST00000597445.1
MCEMP1
mast cell expressed membrane protein 1
chr17_-_31318818 2.60 ENST00000578584.5
ENSG00000265118.5
novel protein
chr7_+_155298561 2.45 ENST00000476756.1
INSIG1
insulin induced gene 1
chr15_-_38560050 2.37 ENST00000558432.5
RASGRP1
RAS guanyl releasing protein 1
chr10_-_127892930 2.14 ENST00000368671.4
CLRN3
clarin 3
chr13_-_40982880 2.04 ENST00000635415.1
ELF1
E74 like ETS transcription factor 1
chr1_-_225999312 1.89 ENST00000272091.8
SDE2
SDE2 telomere maintenance homolog
chr16_+_31527876 1.88 ENST00000302312.9
ENST00000564707.1
AHSP
alpha hemoglobin stabilizing protein
chr3_+_137998735 1.86 ENST00000343735.8
CLDN18
claudin 18
chr19_+_10286971 1.81 ENST00000340992.4
ENST00000393717.2
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr17_-_35560812 1.73 ENST00000674182.1
SLFN14
schlafen family member 14
chr14_-_22815421 1.70 ENST00000674313.1
ENST00000555959.1
SLC7A7
solute carrier family 7 member 7
chr11_+_75717811 1.70 ENST00000198801.10
MOGAT2
monoacylglycerol O-acyltransferase 2
chr11_-_47352693 1.63 ENST00000256993.8
ENST00000399249.6
ENST00000545968.6
MYBPC3
myosin binding protein C3
chr4_-_102345196 1.61 ENST00000683412.1
ENST00000682227.1
SLC39A8
solute carrier family 39 member 8
chr6_+_31706866 1.58 ENST00000375832.5
ENST00000503322.1
LY6G6F
LY6G6F-LY6G6D
lymphocyte antigen 6 family member G6F
LY6G6F-LY6G6D readthrough
chr19_+_10286944 1.55 ENST00000380770.5
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr19_-_38812936 1.54 ENST00000307751.9
ENST00000594209.1
LGALS4
galectin 4
chr12_+_111405861 1.54 ENST00000341259.7
SH2B3
SH2B adaptor protein 3
chr12_-_102950835 1.53 ENST00000546844.1
PAH
phenylalanine hydroxylase
chr4_-_102345061 1.47 ENST00000394833.6
SLC39A8
solute carrier family 39 member 8
chr11_-_57390636 1.47 ENST00000525955.1
ENST00000533605.5
ENST00000311862.10
PRG2
proteoglycan 2, pro eosinophil major basic protein
chr4_+_99574812 1.47 ENST00000422897.6
ENST00000265517.10
MTTP
microsomal triglyceride transfer protein
chr14_+_105486311 1.46 ENST00000330233.11
CRIP1
cysteine rich protein 1
chr9_-_112175185 1.44 ENST00000355396.7
SUSD1
sushi domain containing 1
chr2_+_43838963 1.41 ENST00000272286.4
ABCG8
ATP binding cassette subfamily G member 8
chr2_-_68871382 1.41 ENST00000295379.2
BMP10
bone morphogenetic protein 10
chr22_-_19881369 1.40 ENST00000462330.5
TXNRD2
thioredoxin reductase 2
chr17_+_4932248 1.40 ENST00000329125.6
GP1BA
glycoprotein Ib platelet subunit alpha
chr17_-_49764123 1.39 ENST00000240364.7
ENST00000506156.1
FAM117A
family with sequence similarity 117 member A
chr2_-_43838832 1.37 ENST00000405322.8
ABCG5
ATP binding cassette subfamily G member 5
chr22_-_19881163 1.34 ENST00000485358.5
TXNRD2
thioredoxin reductase 2
chr19_-_13102848 1.32 ENST00000264824.5
LYL1
LYL1 basic helix-loop-helix family member
chr14_+_75522427 1.32 ENST00000286639.8
BATF
basic leucine zipper ATF-like transcription factor
chr13_-_27969295 1.27 ENST00000381020.8
CDX2
caudal type homeobox 2
chr9_-_112175264 1.22 ENST00000374264.6
SUSD1
sushi domain containing 1
chr17_+_4932285 1.18 ENST00000611961.1
GP1BA
glycoprotein Ib platelet subunit alpha
chr14_+_75522531 1.16 ENST00000555504.1
BATF
basic leucine zipper ATF-like transcription factor
chr6_-_30160880 1.12 ENST00000376704.3
TRIM10
tripartite motif containing 10
chr4_-_48681171 1.11 ENST00000505759.1
FRYL
FRY like transcription coactivator
chr9_-_112175283 1.11 ENST00000374270.8
ENST00000374263.7
SUSD1
sushi domain containing 1
chr18_-_31162849 1.09 ENST00000257197.7
ENST00000257198.6
DSC1
desmocollin 1
chr14_-_22815493 1.08 ENST00000555911.1
SLC7A7
solute carrier family 7 member 7
chr17_+_77287891 1.08 ENST00000449803.6
ENST00000431235.6
SEPTIN9
septin 9
chr14_-_22815856 1.02 ENST00000554758.1
ENST00000397528.8
SLC7A7
solute carrier family 7 member 7
chr5_-_135954962 0.98 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
LECT2
leukocyte cell derived chemotaxin 2
chr11_+_10305370 0.97 ENST00000528544.1
ADM
adrenomedullin
chr3_+_148865288 0.96 ENST00000296046.4
CPA3
carboxypeptidase A3
chr14_-_22815801 0.96 ENST00000397532.9
SLC7A7
solute carrier family 7 member 7
chr18_-_2982873 0.95 ENST00000584915.1
LPIN2
lipin 2
chr9_-_97938157 0.87 ENST00000616898.2
HEMGN
hemogen
chr20_+_44401269 0.86 ENST00000443598.6
ENST00000415691.2
HNF4A
hepatocyte nuclear factor 4 alpha
chr8_-_20183090 0.85 ENST00000265808.11
ENST00000522513.5
SLC18A1
solute carrier family 18 member A1
chr17_+_76385256 0.85 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr2_-_40512423 0.85 ENST00000402441.5
ENST00000448531.1
SLC8A1
solute carrier family 8 member A1
chr2_-_201433545 0.83 ENST00000440597.1
TRAK2
trafficking kinesin protein 2
chr7_-_78770859 0.81 ENST00000636717.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr12_-_52601397 0.80 ENST00000549979.1
KRT72
keratin 72
chr17_-_64006880 0.79 ENST00000449662.6
ICAM2
intercellular adhesion molecule 2
chr18_+_22169580 0.78 ENST00000269216.10
GATA6
GATA binding protein 6
chr6_-_30161200 0.78 ENST00000449742.7
TRIM10
tripartite motif containing 10
chr8_-_20183127 0.77 ENST00000276373.10
ENST00000519026.5
ENST00000440926.3
ENST00000437980.3
SLC18A1
solute carrier family 18 member A1
chr11_+_10305065 0.73 ENST00000534464.1
ENST00000278175.10
ENST00000530439.1
ENST00000524948.5
ENST00000528655.5
ENST00000526492.4
ENST00000525063.2
ADM
adrenomedullin
chr2_-_40512361 0.71 ENST00000403092.5
SLC8A1
solute carrier family 8 member A1
chr5_-_142324137 0.70 ENST00000511815.1
SPRY4
sprouty RTK signaling antagonist 4
chr22_-_29388530 0.70 ENST00000357586.7
ENST00000432560.6
ENST00000405198.6
ENST00000317368.11
AP1B1
adaptor related protein complex 1 subunit beta 1
chr6_+_117675448 0.69 ENST00000368494.4
NUS1
NUS1 dehydrodolichyl diphosphate synthase subunit
chr3_+_152269103 0.67 ENST00000459747.1
MBNL1
muscleblind like splicing regulator 1
chr8_-_92095432 0.67 ENST00000518954.5
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr6_+_138377905 0.66 ENST00000573100.2
SMIM28
small integral membrane protein 28
chr19_-_13103151 0.66 ENST00000590974.1
LYL1
LYL1 basic helix-loop-helix family member
chr19_-_11384299 0.63 ENST00000592375.6
ENST00000222139.11
EPOR
erythropoietin receptor
chr1_+_25272527 0.60 ENST00000342055.9
ENST00000357542.8
ENST00000417538.6
ENST00000423810.6
ENST00000568195.5
RHD
Rh blood group D antigen
chr2_+_168901290 0.59 ENST00000429379.2
ENST00000375363.8
ENST00000421979.1
G6PC2
glucose-6-phosphatase catalytic subunit 2
chrX_+_108045050 0.55 ENST00000458383.1
ENST00000217957.10
VSIG1
V-set and immunoglobulin domain containing 1
chr6_+_130018565 0.54 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL3
L3MBTL histone methyl-lysine binding protein 3
chr8_-_92095498 0.51 ENST00000520974.5
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr18_+_3447562 0.49 ENST00000618001.4
TGIF1
TGFB induced factor homeobox 1
chr8_-_92095410 0.48 ENST00000518823.5
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr19_-_55038256 0.48 ENST00000417454.5
ENST00000310373.7
ENST00000333884.2
GP6
glycoprotein VI platelet
chr2_-_213150387 0.47 ENST00000433134.5
IKZF2
IKAROS family zinc finger 2
chr17_+_19411118 0.46 ENST00000575165.6
RNF112
ring finger protein 112
chr2_-_213150236 0.45 ENST00000442445.1
ENST00000342002.6
IKZF2
IKAROS family zinc finger 2
chr4_-_185775484 0.41 ENST00000444771.5
SORBS2
sorbin and SH3 domain containing 2
chr12_+_71938837 0.35 ENST00000333850.4
TPH2
tryptophan hydroxylase 2
chr2_+_118096418 0.34 ENST00000614681.1
INSIG2
insulin induced gene 2
chr4_+_165873231 0.34 ENST00000061240.7
TLL1
tolloid like 1
chr20_-_32207708 0.32 ENST00000246229.5
PLAGL2
PLAG1 like zinc finger 2
chr1_+_50108856 0.31 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAVL4
ELAV like RNA binding protein 4
chrX_+_38006551 0.31 ENST00000297875.7
SYTL5
synaptotagmin like 5
chrX_+_108044967 0.29 ENST00000415430.7
VSIG1
V-set and immunoglobulin domain containing 1
chr4_-_185775890 0.25 ENST00000437304.6
SORBS2
sorbin and SH3 domain containing 2
chr10_+_116545907 0.25 ENST00000369221.2
PNLIP
pancreatic lipase
chr19_+_14028148 0.25 ENST00000431365.3
ENST00000585987.1
RLN3
relaxin 3
chr1_-_205943449 0.24 ENST00000367135.8
ENST00000367134.2
SLC26A9
solute carrier family 26 member 9
chr2_+_137964446 0.24 ENST00000280096.5
ENST00000280097.5
HNMT
histamine N-methyltransferase
chr8_-_144792380 0.22 ENST00000532702.1
ENST00000394920.6
ENST00000528957.6
ENST00000527914.5
RPL8
ribosomal protein L8
chr11_-_66438788 0.18 ENST00000329819.4
ENST00000310999.11
ENST00000430466.6
MRPL11
mitochondrial ribosomal protein L11
chr3_+_152268920 0.18 ENST00000495875.6
ENST00000324210.10
ENST00000493459.5
MBNL1
muscleblind like splicing regulator 1
chr14_-_21476874 0.17 ENST00000649801.1
ENST00000397762.6
RAB2B
RAB2B, member RAS oncogene family
chr1_+_154321076 0.16 ENST00000324978.8
AQP10
aquaporin 10
chr2_+_172928165 0.16 ENST00000535187.5
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr4_+_165873348 0.15 ENST00000507499.5
TLL1
tolloid like 1
chr1_-_206023889 0.13 ENST00000358184.7
ENST00000360218.3
ENST00000678712.1
ENST00000678498.1
CTSE
cathepsin E
chr8_-_92095468 0.13 ENST00000520583.5
ENST00000519061.5
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr3_-_122975369 0.12 ENST00000449546.1
SEMA5B
semaphorin 5B
chr6_-_154247630 0.11 ENST00000519344.5
IPCEF1
interaction protein for cytohesin exchange factors 1
chr8_+_69466837 0.09 ENST00000529134.5
SULF1
sulfatase 1
chr20_+_45306834 0.08 ENST00000343694.8
ENST00000372741.7
ENST00000372743.5
RBPJL
recombination signal binding protein for immunoglobulin kappa J region like
chr5_+_1201588 0.08 ENST00000304460.11
SLC6A19
solute carrier family 6 member 19
chr7_+_142749465 0.07 ENST00000486171.5
ENST00000619214.4
ENST00000311737.12
PRSS1
serine protease 1
chr5_-_33984681 0.07 ENST00000296589.9
SLC45A2
solute carrier family 45 member 2
chr16_+_1431075 0.05 ENST00000640283.2
PERCC1
proline and glutamate rich with coiled coil 1
chr20_+_56392353 0.05 ENST00000415828.5
ENST00000428552.1
CSTF1
cleavage stimulation factor subunit 1
chr10_+_116590956 0.04 ENST00000358834.9
ENST00000528052.5
PNLIPRP1
pancreatic lipase related protein 1
chr7_+_150993773 0.04 ENST00000467517.1
ENST00000484524.5
NOS3
nitric oxide synthase 3
chr1_+_174877430 0.04 ENST00000392064.6
RABGAP1L
RAB GTPase activating protein 1 like
chr10_+_116591010 0.02 ENST00000530319.5
ENST00000527980.5
ENST00000471549.5
ENST00000534537.5
PNLIPRP1
pancreatic lipase related protein 1
chr19_+_35358821 0.01 ENST00000594310.1
FFAR3
free fatty acid receptor 3
chr1_+_154321107 0.00 ENST00000484864.1
AQP10
aquaporin 10

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 10.0 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.8 2.4 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.7 5.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.7 3.7 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.7 2.8 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.6 3.7 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.5 4.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.4 1.5 GO:0002215 defense response to nematode(GO:0002215)
0.4 1.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.3 2.4 GO:0032252 secretory granule localization(GO:0032252)
0.3 0.8 GO:0046521 sphingoid catabolic process(GO:0046521)
0.3 3.1 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.3 1.6 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.2 1.7 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 1.6 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.2 0.7 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.2 0.6 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.2 1.8 GO:0034378 chylomicron assembly(GO:0034378)
0.2 0.8 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.2 0.4 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.2 4.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 1.9 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.2 1.7 GO:0097647 progesterone biosynthetic process(GO:0006701) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 3.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.8 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 1.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 6.2 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 1.4 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.1 1.7 GO:0071287 cellular response to manganese ion(GO:0071287)
0.1 2.5 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 2.0 GO:0001955 blood vessel maturation(GO:0001955)
0.1 3.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 2.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 1.5 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 0.9 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.8 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 3.1 GO:0030220 platelet formation(GO:0030220)
0.1 2.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 1.9 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 1.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 1.5 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 2.8 GO:0000305 response to oxygen radical(GO:0000305)
0.0 1.0 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 3.0 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.3 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.3 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.2 GO:0015793 glycerol transport(GO:0015793)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.5 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 1.8 GO:0070268 cornification(GO:0070268)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.6 2.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.5 6.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.4 1.6 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 3.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 2.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 1.6 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 4.6 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.9 GO:0005833 hemoglobin complex(GO:0005833)
0.1 2.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.8 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.1 GO:0030057 desmosome(GO:0030057)
0.0 9.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.9 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 3.4 GO:0016605 PML body(GO:0016605)
0.0 1.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 10.0 GO:0002113 interleukin-33 binding(GO:0002113)
1.2 3.7 GO:0004998 transferrin receptor activity(GO:0004998)
0.7 3.7 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.4 1.6 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.3 2.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 1.9 GO:0030492 hemoglobin binding(GO:0030492)
0.3 1.5 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.2 1.5 GO:0016936 galactoside binding(GO:0016936)
0.2 4.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 0.6 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2 5.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.7 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 1.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2 0.9 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 2.7 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.2 3.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.8 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 1.4 GO:0031433 telethonin binding(GO:0031433)
0.1 2.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.5 GO:0003680 AT DNA binding(GO:0003680)
0.1 3.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 3.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 3.8 GO:0050699 WW domain binding(GO:0050699)
0.0 6.2 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 1.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.5 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 2.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 6.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.2 PID EPO PATHWAY EPO signaling pathway
0.0 3.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 6.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 3.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 4.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 2.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 4.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 3.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 4.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)