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Illumina Body Map 2 (GSE30611)
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Results for GGAAGAC
Z-value: 0.80
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miRNA associated with seed GGAAGAC
| Name | miRBASE accession |
|---|---|
|
hsa-miR-7-5p
|
MIMAT0000252 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_46825949 Show fit | 2.52 |
ENST00000547477.5
ENST00000447411.5 ENST00000266579.9 |
solute carrier family 38 member 4 |
|
| chr8_+_78516329 Show fit | 2.46 |
ENST00000396418.7
ENST00000352966.9 |
cAMP-dependent protein kinase inhibitor alpha |
|
| chr13_-_109786567 Show fit | 1.82 |
ENST00000375856.5
|
insulin receptor substrate 2 |
|
| chr19_+_53909263 Show fit | 1.81 |
ENST00000391767.6
|
calcium voltage-gated channel auxiliary subunit gamma 7 |
|
| chr9_-_120714457 Show fit | 1.77 |
ENST00000373930.4
|
multiple EGF like domains 9 |
|
| chr1_-_39691393 Show fit | 1.57 |
ENST00000372844.8
|
hippocalcin like 4 |
|
| chr7_-_143362687 Show fit | 1.51 |
ENST00000409578.5
ENST00000443739.7 ENST00000409346.5 |
family with sequence similarity 131 member B |
|
| chr17_+_70169516 Show fit | 1.43 |
ENST00000243457.4
|
potassium inwardly rectifying channel subfamily J member 2 |
|
| chr5_+_31532277 Show fit | 1.43 |
ENST00000507818.6
ENST00000325366.14 |
chromosome 5 open reading frame 22 |
|
| chr3_-_125595488 Show fit | 1.37 |
ENST00000296220.6
|
oxysterol binding protein like 11 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GGAAGAC
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.5 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 2.1 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.2 | 1.8 | GO:0010746 | regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) |
| 0.3 | 1.4 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
| 0.2 | 1.4 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.0 | 1.3 | GO:0006851 | mitochondrial calcium ion transport(GO:0006851) |
| 0.0 | 1.3 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 1.2 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.1 | 1.1 | GO:0030309 | poly-N-acetyllactosamine metabolic process(GO:0030309) |
| 0.0 | 1.1 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.5 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.2 | 1.4 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 0.0 | 1.4 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 1.3 | GO:0046930 | pore complex(GO:0046930) |
| 0.1 | 1.1 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.0 | 1.1 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 1.1 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.3 | 1.0 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.0 | 1.0 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.0 | 0.9 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.6 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.1 | 2.5 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.2 | 2.4 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.0 | 2.4 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.0 | 2.4 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.0 | 1.6 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.1 | 1.5 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.1 | 1.3 | GO:0015288 | porin activity(GO:0015288) |
| 0.3 | 1.1 | GO:0050698 | proteoglycan sulfotransferase activity(GO:0050698) |
| 0.0 | 1.1 | GO:0015002 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.9 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 1.9 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.0 | 0.9 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 0.9 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.0 | 0.8 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.8 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 0.7 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 0.7 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 0.5 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 0.3 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.2 | REACTOME SOS MEDIATED SIGNALLING | Genes involved in SOS-mediated signalling |
| 0.0 | 2.9 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 2.1 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 1.8 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.0 | 1.6 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 1.5 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 1.5 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 1.1 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 1.0 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 1.0 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |