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Illumina Body Map 2 (GSE30611)

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Results for GGAGUGU

Z-value: 0.26

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miRNA associated with seed GGAGUGU

NamemiRBASE accession
hsa-miR-122-5p
MIMAT0000421

Activity profile of GGAGUGU motif

Sorted Z-values of GGAGUGU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_95596507 0.76 ENST00000005178.6
PDK4
pyruvate dehydrogenase kinase 4
chr10_-_73096850 0.43 ENST00000307116.6
ENST00000373008.6
ENST00000394890.7
P4HA1
prolyl 4-hydroxylase subunit alpha 1
chr16_+_30065753 0.39 ENST00000642816.3
ENST00000643777.4
ENST00000569798.5
ALDOA
aldolase, fructose-bisphosphate A
chr17_+_47531052 0.30 ENST00000532729.6
ENST00000322157.9
NPEPPS
aminopeptidase puromycin sensitive
chr19_+_46297032 0.26 ENST00000377670.9
HIF3A
hypoxia inducible factor 3 subunit alpha
chr1_-_72282457 0.23 ENST00000357731.10
NEGR1
neuronal growth regulator 1
chr8_+_144104454 0.22 ENST00000322428.10
MAF1
MAF1 homolog, negative regulator of RNA polymerase III
chr14_+_37197921 0.20 ENST00000684589.1
ENST00000327441.11
MIPOL1
mirror-image polydactyly 1
chr5_+_163437569 0.20 ENST00000512163.5
ENST00000393929.5
ENST00000510097.5
ENST00000340828.7
ENST00000511490.4
ENST00000510664.5
CCNG1
cyclin G1
chr1_+_15736251 0.18 ENST00000294454.6
SLC25A34
solute carrier family 25 member 34
chr1_+_24745396 0.16 ENST00000374379.9
CLIC4
chloride intracellular channel 4
chrX_-_135973975 0.16 ENST00000305963.3
ENST00000680510.1
ENST00000679621.1
MMGT1
membrane magnesium transporter 1
chr19_-_8308287 0.16 ENST00000537716.6
ENST00000301458.10
CD320
CD320 molecule
chr8_-_29350666 0.15 ENST00000240100.7
DUSP4
dual specificity phosphatase 4
chr12_-_56300358 0.14 ENST00000550655.5
ENST00000548567.5
ENST00000551430.6
CS
citrate synthase
chr2_-_86721122 0.13 ENST00000604011.5
RNF103-CHMP3
RNF103-CHMP3 readthrough
chr10_-_32056376 0.12 ENST00000302418.5
KIF5B
kinesin family member 5B
chr2_-_86563382 0.12 ENST00000263856.9
CHMP3
charged multivesicular body protein 3
chr19_-_2456924 0.11 ENST00000325327.4
LMNB2
lamin B2
chr6_+_108559742 0.10 ENST00000343882.10
FOXO3
forkhead box O3
chr6_-_46015812 0.10 ENST00000544153.3
ENST00000339561.12
CLIC5
chloride intracellular channel 5
chr1_-_205813177 0.10 ENST00000367137.4
SLC41A1
solute carrier family 41 member 1
chr19_+_41310148 0.08 ENST00000269967.4
CCDC97
coiled-coil domain containing 97
chr1_-_244864560 0.08 ENST00000444376.7
HNRNPU
heterogeneous nuclear ribonucleoprotein U
chr1_-_208244375 0.07 ENST00000367033.4
PLXNA2
plexin A2
chr19_-_46788586 0.07 ENST00000542575.6
SLC1A5
solute carrier family 1 member 5
chr4_-_145938422 0.06 ENST00000656985.1
ENST00000652097.1
ENST00000503462.3
ENST00000379448.9
ENST00000513840.2
ZNF827
zinc finger protein 827
chr13_-_98577131 0.06 ENST00000397517.6
STK24
serine/threonine kinase 24
chr7_-_33062750 0.06 ENST00000610140.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr17_-_4366616 0.06 ENST00000572484.5
ENST00000396981.7
UBE2G1
ubiquitin conjugating enzyme E2 G1
chr19_-_48811012 0.06 ENST00000545387.6
ENST00000402551.5
ENST00000598162.5
ENST00000316273.11
ENST00000599246.5
BCAT2
branched chain amino acid transaminase 2
chr21_+_39745407 0.05 ENST00000380588.4
IGSF5
immunoglobulin superfamily member 5
chr2_+_14632688 0.05 ENST00000331243.4
ENST00000295092.3
LRATD1
LRAT domain containing 1
chr5_+_96936071 0.05 ENST00000231368.10
LNPEP
leucyl and cystinyl aminopeptidase
chr7_+_114414997 0.05 ENST00000462331.5
ENST00000393491.7
ENST00000403559.8
ENST00000408937.7
ENST00000393498.6
ENST00000393495.7
ENST00000378237.7
FOXP2
forkhead box P2
chr11_+_112025367 0.05 ENST00000679614.1
ENST00000679878.1
ENST00000280346.11
ENST00000681339.1
ENST00000681328.1
ENST00000681316.1
ENST00000531306.2
ENST00000680331.1
ENST00000393051.5
DLAT
dihydrolipoamide S-acetyltransferase
chr16_-_30370396 0.05 ENST00000409939.8
TBC1D10B
TBC1 domain family member 10B
chr5_-_142012973 0.05 ENST00000503794.5
ENST00000510194.5
ENST00000504424.1
ENST00000513454.5
ENST00000311337.11
ENST00000503229.5
ENST00000500692.6
ENST00000504139.5
ENST00000505689.5
GNPDA1
glucosamine-6-phosphate deaminase 1
chr19_+_46601296 0.04 ENST00000598871.5
ENST00000291295.14
ENST00000594523.5
CALM3
calmodulin 3
chr4_-_52659238 0.04 ENST00000451218.6
ENST00000441222.8
USP46
ubiquitin specific peptidase 46
chr2_-_219060914 0.04 ENST00000295731.7
IHH
Indian hedgehog signaling molecule
chr20_+_33993646 0.04 ENST00000375114.7
ENST00000448364.5
RALY
RALY heterogeneous nuclear ribonucleoprotein
chr19_-_6279921 0.03 ENST00000252674.9
MLLT1
MLLT1 super elongation complex subunit
chr1_-_109397888 0.03 ENST00000256637.8
SORT1
sortilin 1
chr14_-_103057509 0.03 ENST00000361246.7
CDC42BPB
CDC42 binding protein kinase beta
chr14_-_77320855 0.03 ENST00000556394.2
ENST00000261534.9
POMT2
protein O-mannosyltransferase 2
chr8_-_67343768 0.03 ENST00000262215.8
ARFGEF1
ADP ribosylation factor guanine nucleotide exchange factor 1
chr3_+_47282930 0.03 ENST00000232766.6
ENST00000437353.5
KLHL18
kelch like family member 18
chr17_-_29589571 0.03 ENST00000579937.5
ENST00000335356.7
GIT1
GIT ArfGAP 1
chrX_+_155026835 0.03 ENST00000369498.8
FUNDC2
FUN14 domain containing 2
chr1_-_161132659 0.03 ENST00000368006.8
ENST00000490843.6
ENST00000545495.5
DEDD
death effector domain containing
chr7_+_94656325 0.02 ENST00000482108.1
ENST00000488574.5
ENST00000612748.1
ENST00000613043.1
PEG10
paternally expressed 10
chr11_-_108498374 0.02 ENST00000323468.10
POGLUT3
protein O-glucosyltransferase 3
chrX_-_49043345 0.02 ENST00000315869.8
TFE3
transcription factor binding to IGHM enhancer 3
chr10_-_59906509 0.02 ENST00000263102.7
CCDC6
coiled-coil domain containing 6
chr1_-_153922901 0.01 ENST00000634401.1
ENST00000368655.5
GATAD2B
GATA zinc finger domain containing 2B
chr8_-_116874746 0.01 ENST00000297338.7
RAD21
RAD21 cohesin complex component
chr5_-_11904417 0.01 ENST00000304623.13
CTNND2
catenin delta 2
chr2_-_96145431 0.01 ENST00000288943.5
DUSP2
dual specificity phosphatase 2
chr4_+_171813397 0.00 ENST00000506823.6
GALNTL6
polypeptide N-acetylgalactosaminyltransferase like 6
chr8_+_144358557 0.00 ENST00000530047.5
ENST00000527078.6
ENST00000674870.1
ENST00000526338.7
ENST00000402965.5
ENST00000329994.7
ENST00000526752.3
ENST00000533662.2
ENST00000534725.6
ENST00000674929.1
ENST00000675597.1
ENST00000643944.2
ENST00000675121.1
SLC52A2
solute carrier family 52 member 2
chr1_+_28259473 0.00 ENST00000253063.4
SESN2
sestrin 2
chr1_+_161118083 0.00 ENST00000368009.7
ENST00000368007.8
ENST00000392190.9
ENST00000368008.5
NIT1
nitrilase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of GGAGUGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.2 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:0021758 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.0 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.2 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.1 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.0 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex