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Illumina Body Map 2 (GSE30611)

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Results for GLIS1

Z-value: 0.29

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Transcription factors associated with GLIS1

Gene Symbol Gene ID Gene Info
ENSG00000174332.5 GLIS family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS1hg38_v1_chr1_-_53738024_537381060.503.9e-03Click!

Activity profile of GLIS1 motif

Sorted Z-values of GLIS1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_107044689 0.80 ENST00000265717.5
protein kinase cAMP-dependent type II regulatory subunit beta
chr18_+_11751494 0.57 ENST00000269162.9
G protein subunit alpha L
chr18_+_11751467 0.54 ENST00000535121.5
G protein subunit alpha L
chr11_+_68903849 0.51 ENST00000675615.1
ENST00000255078.8
immunoglobulin mu DNA binding protein 2
chr19_-_49325181 0.51 ENST00000454748.7
ENST00000335875.9
ENST00000598828.1
solute carrier family 6 member 16
chr18_-_63158208 0.49 ENST00000678301.1
BCL2 apoptosis regulator
chr18_+_11752041 0.39 ENST00000423027.8
G protein subunit alpha L
chr11_+_68684534 0.32 ENST00000265643.4
galanin and GMAP prepropeptide
chr19_-_37906588 0.25 ENST00000447313.7
WD repeat domain 87
chr11_-_68903796 0.19 ENST00000362034.7
mitochondrial ribosomal protein L21
chr19_+_40191410 0.17 ENST00000253055.8
mitogen-activated protein kinase kinase kinase 10
chr16_+_58025745 0.16 ENST00000219271.4
matrix metallopeptidase 15
chr19_-_41959266 0.07 ENST00000600292.5
ENST00000601078.5
ENST00000601891.5
ENST00000222008.11
Rab acceptor 1
chr19_+_1275508 0.06 ENST00000409293.6
family with sequence similarity 174 member C

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.3 GO:0051795 positive regulation of catagen(GO:0051795)
0.1 0.8 GO:0097338 response to clozapine(GO:0097338)
0.0 1.5 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0032797 SMN complex(GO:0032797)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0046930 pore complex(GO:0046930)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 1.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins