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Illumina Body Map 2 (GSE30611)
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Results for GMEB1
Z-value: 0.96
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Transcription factors associated with GMEB1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GMEB1 | hg38_v1_chr1_+_28668746_28668815 | 0.31 | 8.6e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of GMEB1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.3 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
| 0.0 | 3.1 | GO:0007286 | spermatid development(GO:0007286) |
| 0.1 | 2.9 | GO:0003351 | epithelial cilium movement(GO:0003351) |
| 0.1 | 2.7 | GO:0030261 | chromosome condensation(GO:0030261) |
| 0.0 | 2.7 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.3 | 2.5 | GO:0007506 | gonadal mesoderm development(GO:0007506) |
| 0.0 | 2.4 | GO:0043029 | T cell homeostasis(GO:0043029) |
| 0.0 | 2.4 | GO:0018107 | peptidyl-threonine phosphorylation(GO:0018107) |
| 0.2 | 2.3 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.0 | 2.3 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.1 | GO:0005813 | centrosome(GO:0005813) |
| 0.0 | 6.6 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 3.5 | GO:0031674 | I band(GO:0031674) |
| 0.7 | 2.9 | GO:0097229 | sperm end piece(GO:0097229) |
| 0.1 | 2.5 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 2.4 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 2.4 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.1 | 2.1 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 2.1 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 2.1 | GO:0002102 | podosome(GO:0002102) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.5 | GO:0008201 | heparin binding(GO:0008201) |
| 0.0 | 3.4 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 2.6 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.1 | 2.3 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.0 | 2.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 2.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 1.9 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.2 | 1.8 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.2 | 1.8 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.2 | 1.7 | GO:0001515 | opioid peptide activity(GO:0001515) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.6 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 3.3 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 2.6 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 2.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 2.4 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 2.1 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 1.9 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 1.8 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 1.7 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 1.6 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.7 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.0 | 3.7 | REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | Genes involved in Recruitment of mitotic centrosome proteins and complexes |
| 0.1 | 2.8 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 2.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 2.5 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 2.3 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.0 | 1.8 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.1 | 1.5 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.1 | 1.4 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 1.3 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |