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Illumina Body Map 2 (GSE30611)

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Results for GSC_GSC2

Z-value: 0.85

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Transcription factors associated with GSC_GSC2

Gene Symbol Gene ID Gene Info
GSC
ENSG00000133937.5 goosecoid homeobox
GSC2
ENSG00000063515.3 goosecoid homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GSChg38_v1_chr14_-_94770102_94770130-0.512.8e-03Click!
GSC2hg38_v1_chr22_-_19150292_191502920.163.7e-01Click!

Activity profile of GSC_GSC2 motif

Sorted Z-values of GSC_GSC2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_61755372 2.96 ENST00000265460.9
MYRF
myelin regulatory factor
chr15_-_26939518 2.75 ENST00000541819.6
GABRB3
gamma-aminobutyric acid type A receptor subunit beta3
chr3_-_10505508 2.46 ENST00000643662.1
ENST00000397077.6
ENST00000360273.7
ATP2B2
ATPase plasma membrane Ca2+ transporting 2
chr6_+_34466059 2.37 ENST00000620693.4
ENST00000244458.7
ENST00000374043.6
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr9_+_100442271 2.09 ENST00000502978.1
MSANTD3-TMEFF1
MSANTD3-TMEFF1 readthrough
chr17_+_70104848 2.00 ENST00000392670.5
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr3_-_179974078 1.97 ENST00000464614.5
ENST00000476138.5
ENST00000463761.1
PEX5L
peroxisomal biogenesis factor 5 like
chr17_+_70104991 1.81 ENST00000587698.5
ENST00000587892.1
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr7_+_29122274 1.76 ENST00000582692.2
ENST00000644824.1
ENSG00000285412.1
ENSG00000285162.1
novel transcript, antisense to CPVL
chimerin 2
chr10_-_102418748 1.75 ENST00000020673.6
PSD
pleckstrin and Sec7 domain containing
chr2_+_120013111 1.73 ENST00000331393.8
ENST00000443124.5
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr2_-_174847015 1.68 ENST00000650938.1
CHN1
chimerin 1
chr18_-_37565714 1.63 ENST00000591287.5
ENST00000601019.5
ENST00000601392.5
CELF4
CUGBP Elav-like family member 4
chr18_-_37565628 1.58 ENST00000334919.9
ENST00000591282.5
ENST00000588597.5
CELF4
CUGBP Elav-like family member 4
chr2_-_174846405 1.52 ENST00000409597.5
ENST00000413882.6
CHN1
chimerin 1
chr4_+_153222307 1.46 ENST00000675899.1
ENST00000675611.1
ENST00000674872.1
ENST00000676167.1
TRIM2
tripartite motif containing 2
chr3_-_179974254 1.40 ENST00000468741.5
PEX5L
peroxisomal biogenesis factor 5 like
chr4_+_153222402 1.36 ENST00000676335.1
ENST00000675146.1
TRIM2
tripartite motif containing 2
chr13_-_61427849 1.33 ENST00000409186.1
ENST00000472649.2
ENSG00000197991.11
LINC02339
novel protein
long intergenic non-protein coding RNA 2339
chr11_-_63015831 1.32 ENST00000430500.6
ENST00000336232.7
SLC22A8
solute carrier family 22 member 8
chr17_+_46590669 1.29 ENST00000398238.8
NSF
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
chr11_-_62984957 1.28 ENST00000377871.7
ENST00000360421.9
SLC22A6
solute carrier family 22 member 6
chr2_+_120013068 1.25 ENST00000443902.6
ENST00000263713.10
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr15_-_52191387 1.19 ENST00000261837.12
GNB5
G protein subunit beta 5
chr3_+_49021071 1.17 ENST00000395458.6
NDUFAF3
NADH:ubiquinone oxidoreductase complex assembly factor 3
chrX_+_12137409 1.09 ENST00000672010.1
FRMPD4
FERM and PDZ domain containing 4
chr2_+_170783781 1.04 ENST00000409885.1
ERICH2
glutamate rich 2
chr16_-_68236069 1.03 ENST00000473183.7
ENST00000565858.5
ESRP2
epithelial splicing regulatory protein 2
chr14_-_22926413 1.03 ENST00000556043.5
PRMT5
protein arginine methyltransferase 5
chr5_+_161848314 1.02 ENST00000437025.6
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
chrX_-_24647300 1.01 ENST00000379144.7
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr20_+_35968566 0.98 ENST00000373973.7
ENST00000349339.5
ENST00000489667.1
ENST00000538900.1
CNBD2
cyclic nucleotide binding domain containing 2
chr5_+_161848112 0.97 ENST00000393943.10
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
chrX_-_24647091 0.96 ENST00000356768.8
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr17_+_4740042 0.95 ENST00000592813.5
ZMYND15
zinc finger MYND-type containing 15
chr17_+_4739791 0.93 ENST00000433935.6
ZMYND15
zinc finger MYND-type containing 15
chrX_-_6228835 0.93 ENST00000381095.8
NLGN4X
neuroligin 4 X-linked
chr12_+_77830886 0.93 ENST00000397909.7
ENST00000549464.5
NAV3
neuron navigator 3
chr12_+_14973020 0.92 ENST00000266395.3
PDE6H
phosphodiesterase 6H
chr18_-_43277482 0.92 ENST00000255224.8
ENST00000590752.5
ENST00000596867.1
SYT4
synaptotagmin 4
chr17_+_4740005 0.89 ENST00000269289.10
ZMYND15
zinc finger MYND-type containing 15
chr2_-_240820945 0.88 ENST00000428768.2
ENST00000650053.1
ENST00000650130.1
KIF1A
kinesin family member 1A
chr18_-_26863187 0.88 ENST00000440832.7
AQP4
aquaporin 4
chr18_+_34710249 0.87 ENST00000680346.1
ENST00000348997.9
ENST00000681274.1
ENST00000680822.1
ENST00000680767.2
ENST00000597599.5
ENST00000444659.6
DTNA
dystrobrevin alpha
chr12_+_57578238 0.86 ENST00000675907.1
KIF5A
kinesin family member 5A
chr10_-_24723871 0.86 ENST00000396432.7
ARHGAP21
Rho GTPase activating protein 21
chrX_+_140091415 0.81 ENST00000453380.2
ENSG00000230707.2
novel protein (LOC389895)
chrX_-_139642518 0.80 ENST00000370573.8
ENST00000338585.6
MCF2
MCF.2 cell line derived transforming sequence
chr5_+_76818933 0.80 ENST00000514165.1
F2RL1
F2R like trypsin receptor 1
chr18_-_37565765 0.79 ENST00000361795.9
ENST00000420428.7
CELF4
CUGBP Elav-like family member 4
chr5_-_147081462 0.79 ENST00000508267.5
ENST00000504198.5
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr5_-_150758497 0.78 ENST00000521533.1
ENST00000424236.5
DCTN4
dynactin subunit 4
chr1_+_171970115 0.78 ENST00000523513.1
DNM3
dynamin 3
chr10_-_125161056 0.77 ENST00000530884.1
CTBP2
C-terminal binding protein 2
chr12_-_113136224 0.76 ENST00000546530.5
ENST00000261729.9
RASAL1
RAS protein activator like 1
chr2_+_172928165 0.76 ENST00000535187.5
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr10_-_48274567 0.75 ENST00000636244.1
ENST00000374201.8
FRMPD2
FERM and PDZ domain containing 2
chr5_+_159865080 0.75 ENST00000641205.1
ADRA1B
adrenoceptor alpha 1B
chr17_-_42112674 0.75 ENST00000251642.8
ENST00000591220.5
DHX58
DExH-box helicase 58
chr5_-_147081428 0.73 ENST00000394413.7
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr12_-_49130113 0.73 ENST00000549870.5
TUBA1B
tubulin alpha 1b
chr18_-_72865680 0.72 ENST00000397929.5
NETO1
neuropilin and tolloid like 1
chr3_-_98522514 0.72 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
CLDND1
claudin domain containing 1
chr10_-_72954790 0.71 ENST00000373032.4
PLA2G12B
phospholipase A2 group XIIB
chr3_-_183400538 0.70 ENST00000640043.1
MCF2L2
MCF.2 cell line derived transforming sequence-like 2
chr2_-_70553638 0.69 ENST00000444975.5
ENST00000445399.5
ENST00000295400.11
ENST00000418333.6
TGFA
transforming growth factor alpha
chr20_+_34704713 0.68 ENST00000414082.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr2_+_127418420 0.67 ENST00000234071.8
ENST00000429925.5
ENST00000442644.5
PROC
protein C, inactivator of coagulation factors Va and VIIIa
chr10_+_17951906 0.65 ENST00000377371.3
ENST00000377369.7
SLC39A12
solute carrier family 39 member 12
chr3_-_170908626 0.64 ENST00000295822.7
ENST00000474096.5
EIF5A2
eukaryotic translation initiation factor 5A2
chr22_-_19150292 0.63 ENST00000086933.3
GSC2
goosecoid homeobox 2
chr8_-_80080816 0.63 ENST00000520527.5
ENST00000517427.5
ENST00000379097.7
ENST00000448733.3
TPD52
tumor protein D52
chr19_+_2476118 0.63 ENST00000215631.9
ENST00000587345.1
GADD45B
growth arrest and DNA damage inducible beta
chr11_-_70717994 0.62 ENST00000659264.1
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr6_-_42722590 0.61 ENST00000230381.7
PRPH2
peripherin 2
chr1_+_197268222 0.60 ENST00000367400.8
ENST00000638467.1
ENST00000367399.6
CRB1
crumbs cell polarity complex component 1
chr1_-_47190013 0.59 ENST00000294338.7
PDZK1IP1
PDZK1 interacting protein 1
chrX_+_101078861 0.58 ENST00000372930.5
TMEM35A
transmembrane protein 35A
chrX_-_139642889 0.58 ENST00000370576.9
MCF2
MCF.2 cell line derived transforming sequence
chr18_-_37565825 0.57 ENST00000603232.6
CELF4
CUGBP Elav-like family member 4
chr11_-_62984690 0.56 ENST00000421062.2
ENST00000458333.6
SLC22A6
solute carrier family 22 member 6
chr1_-_201171545 0.56 ENST00000367333.6
TMEM9
transmembrane protein 9
chr6_-_40587314 0.56 ENST00000338305.7
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr17_+_50834581 0.55 ENST00000426127.1
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr10_+_17951885 0.54 ENST00000377374.8
SLC39A12
solute carrier family 39 member 12
chr15_+_62758585 0.54 ENST00000472902.1
TLN2
talin 2
chr10_+_17951825 0.53 ENST00000539911.5
SLC39A12
solute carrier family 39 member 12
chr4_+_169620509 0.53 ENST00000347613.8
CLCN3
chloride voltage-gated channel 3
chrX_-_139642835 0.53 ENST00000536274.5
MCF2
MCF.2 cell line derived transforming sequence
chr11_-_72041945 0.53 ENST00000543009.5
NUMA1
nuclear mitotic apparatus protein 1
chr6_-_154247422 0.51 ENST00000519190.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr5_+_141489150 0.51 ENST00000610789.1
PCDHGC5
protocadherin gamma subfamily C, 5
chr6_-_154247630 0.50 ENST00000519344.5
IPCEF1
interaction protein for cytohesin exchange factors 1
chr14_-_100568070 0.49 ENST00000557378.6
ENST00000443071.6
ENST00000637646.1
BEGAIN
brain enriched guanylate kinase associated
chr18_+_8717371 0.49 ENST00000359865.7
MTCL1
microtubule crosslinking factor 1
chr10_-_84241538 0.49 ENST00000372105.4
LRIT1
leucine rich repeat, Ig-like and transmembrane domains 1
chr3_-_193554952 0.49 ENST00000392443.7
ATP13A4
ATPase 13A4
chr5_+_173889337 0.46 ENST00000520867.5
ENST00000334035.9
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr3_-_49021045 0.46 ENST00000440857.5
DALRD3
DALR anticodon binding domain containing 3
chr1_+_35558506 0.45 ENST00000437806.1
NCDN
neurochondrin
chr11_-_72041522 0.45 ENST00000544238.5
NUMA1
nuclear mitotic apparatus protein 1
chr12_-_54981838 0.44 ENST00000316577.12
TESPA1
thymocyte expressed, positive selection associated 1
chr7_-_105269007 0.44 ENST00000357311.7
SRPK2
SRSF protein kinase 2
chr11_-_128842467 0.44 ENST00000392664.2
KCNJ1
potassium inwardly rectifying channel subfamily J member 1
chr13_+_35476740 0.43 ENST00000537702.5
NBEA
neurobeachin
chr20_-_41366805 0.42 ENST00000332312.4
EMILIN3
elastin microfibril interfacer 3
chr9_+_12693327 0.42 ENST00000388918.10
TYRP1
tyrosinase related protein 1
chr13_-_94479671 0.42 ENST00000377028.10
ENST00000446125.1
DCT
dopachrome tautomerase
chr14_-_100568475 0.41 ENST00000553553.6
BEGAIN
brain enriched guanylate kinase associated
chr15_+_43800586 0.40 ENST00000442995.4
ENST00000458412.2
HYPK
huntingtin interacting protein K
chr3_-_193554799 0.40 ENST00000295548.3
ATP13A4
ATPase 13A4
chr4_+_169620527 0.40 ENST00000360642.7
ENST00000512813.5
ENST00000513761.6
CLCN3
chloride voltage-gated channel 3
chr15_+_33310946 0.39 ENST00000415757.7
ENST00000634891.2
ENST00000389232.9
ENST00000622037.1
RYR3
ryanodine receptor 3
chr11_-_40294089 0.39 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr16_+_81238682 0.39 ENST00000258168.7
ENST00000564552.1
BCO1
beta-carotene oxygenase 1
chr18_+_34710307 0.38 ENST00000679796.1
DTNA
dystrobrevin alpha
chr4_+_158806069 0.38 ENST00000512986.5
FNIP2
folliculin interacting protein 2
chr3_-_19934189 0.38 ENST00000295824.14
EFHB
EF-hand domain family member B
chr18_-_43277364 0.38 ENST00000593720.1
SYT4
synaptotagmin 4
chr17_-_28576882 0.37 ENST00000395319.7
ENST00000581807.5
ENST00000226253.9
ENST00000584086.5
ENST00000395321.6
ALDOC
aldolase, fructose-bisphosphate C
chr11_-_72041792 0.35 ENST00000537930.5
NUMA1
nuclear mitotic apparatus protein 1
chr16_-_75701459 0.35 ENST00000633875.4
DUXB
double homeobox B
chr2_-_27264083 0.34 ENST00000432351.5
SLC30A3
solute carrier family 30 member 3
chr7_+_8435187 0.34 ENST00000429542.1
NXPH1
neurexophilin 1
chr4_-_101347551 0.34 ENST00000525819.1
PPP3CA
protein phosphatase 3 catalytic subunit alpha
chr12_-_54588636 0.34 ENST00000257905.13
PPP1R1A
protein phosphatase 1 regulatory inhibitor subunit 1A
chr6_+_31620701 0.33 ENST00000376033.3
ENST00000376007.8
PRRC2A
proline rich coiled-coil 2A
chr17_-_19748355 0.33 ENST00000494157.6
ALDH3A1
aldehyde dehydrogenase 3 family member A1
chr18_-_66604076 0.32 ENST00000540086.5
ENST00000580157.2
ENST00000262150.7
CDH19
cadherin 19
chr7_-_38929550 0.32 ENST00000418457.6
VPS41
VPS41 subunit of HOPS complex
chr7_+_138797952 0.32 ENST00000397602.7
ENST00000442682.7
ENST00000458494.1
ENST00000413208.1
TMEM213
transmembrane protein 213
chr17_-_4739866 0.31 ENST00000574412.6
ENST00000293778.12
CXCL16
C-X-C motif chemokine ligand 16
chr2_-_29921580 0.31 ENST00000389048.8
ALK
ALK receptor tyrosine kinase
chr19_+_3708378 0.31 ENST00000541714.7
ENST00000539908.6
TJP3
tight junction protein 3
chr7_+_8435063 0.31 ENST00000438764.1
NXPH1
neurexophilin 1
chr5_-_178996184 0.30 ENST00000650031.1
GRM6
glutamate metabotropic receptor 6
chr17_-_40703744 0.30 ENST00000264651.3
KRT24
keratin 24
chr13_+_113667213 0.30 ENST00000335678.7
GRK1
G protein-coupled receptor kinase 1
chrY_+_14522573 0.29 ENST00000643089.1
ENST00000382872.5
NLGN4Y
neuroligin 4 Y-linked
chr12_+_69739370 0.28 ENST00000550536.5
ENST00000362025.9
RAB3IP
RAB3A interacting protein
chr12_-_13095664 0.28 ENST00000337630.10
ENST00000545699.1
GSG1
germ cell associated 1
chr11_-_45918789 0.28 ENST00000532681.5
PEX16
peroxisomal biogenesis factor 16
chr5_+_64165815 0.28 ENST00000389100.9
ENST00000296615.10
RNF180
ring finger protein 180
chr5_-_33984636 0.28 ENST00000382102.7
ENST00000509381.1
SLC45A2
solute carrier family 45 member 2
chr15_+_48206286 0.27 ENST00000396577.7
ENST00000380993.8
SLC12A1
solute carrier family 12 member 1
chr2_-_61017174 0.26 ENST00000407787.5
ENST00000398658.2
PUS10
pseudouridine synthase 10
chr15_-_31160954 0.26 ENST00000558445.5
ENST00000559177.5
TRPM1
transient receptor potential cation channel subfamily M member 1
chrX_-_124963768 0.26 ENST00000371130.7
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr9_+_17135017 0.26 ENST00000380641.4
ENST00000380647.8
CNTLN
centlein
chr10_-_92243246 0.26 ENST00000412050.8
ENST00000614585.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr2_-_55269335 0.26 ENST00000441307.5
MTIF2
mitochondrial translational initiation factor 2
chr5_-_16738341 0.25 ENST00000515803.5
MYO10
myosin X
chr12_+_6944009 0.25 ENST00000229281.6
C12orf57
chromosome 12 open reading frame 57
chr2_-_55296361 0.24 ENST00000647547.1
CCDC88A
coiled-coil domain containing 88A
chr16_-_57971121 0.24 ENST00000251102.13
CNGB1
cyclic nucleotide gated channel subunit beta 1
chr14_+_30577752 0.24 ENST00000547532.5
ENST00000555429.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr9_+_2015186 0.23 ENST00000357248.8
ENST00000450198.6
ENST00000634287.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_-_170908587 0.23 ENST00000487522.5
ENST00000474417.1
EIF5A2
eukaryotic translation initiation factor 5A2
chr7_-_138798104 0.23 ENST00000353492.4
ATP6V0A4
ATPase H+ transporting V0 subunit a4
chr1_-_165445088 0.22 ENST00000359842.10
RXRG
retinoid X receptor gamma
chr2_+_218607914 0.22 ENST00000417849.5
PLCD4
phospholipase C delta 4
chr8_-_113436883 0.22 ENST00000455883.2
ENST00000297405.10
CSMD3
CUB and Sushi multiple domains 3
chr7_-_138798188 0.22 ENST00000310018.7
ATP6V0A4
ATPase H+ transporting V0 subunit a4
chr5_+_141489066 0.22 ENST00000252087.3
PCDHGC5
protocadherin gamma subfamily C, 5
chr1_+_18630839 0.21 ENST00000420770.7
PAX7
paired box 7
chr15_+_33310993 0.21 ENST00000634418.1
ENST00000634750.1
RYR3
ryanodine receptor 3
chr1_-_26306989 0.21 ENST00000450041.5
UBXN11
UBX domain protein 11
chr12_+_53425070 0.21 ENST00000550839.1
AMHR2
anti-Mullerian hormone receptor type 2
chr12_-_13095628 0.20 ENST00000457134.6
ENST00000537302.5
GSG1
germ cell associated 1
chr15_-_31161157 0.19 ENST00000542188.5
TRPM1
transient receptor potential cation channel subfamily M member 1
chr9_+_69145463 0.19 ENST00000636438.1
TJP2
tight junction protein 2
chr7_-_128775793 0.19 ENST00000249389.3
OPN1SW
opsin 1, short wave sensitive
chr16_-_31064952 0.19 ENST00000426488.6
ZNF668
zinc finger protein 668
chr12_+_6944065 0.19 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr1_+_165543992 0.18 ENST00000294818.2
LRRC52
leucine rich repeat containing 52
chr3_-_14178615 0.18 ENST00000511155.1
XPC
XPC complex subunit, DNA damage recognition and repair factor
chr4_-_146521830 0.18 ENST00000511374.5
SLC10A7
solute carrier family 10 member 7
chr3_+_4680617 0.18 ENST00000648212.1
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
chr3_+_130931893 0.17 ENST00000504612.5
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr2_+_119760141 0.17 ENST00000420482.5
ENST00000488279.6
PTPN4
protein tyrosine phosphatase non-receptor type 4
chr15_+_64151706 0.17 ENST00000325881.9
SNX22
sorting nexin 22
chr19_+_3708342 0.17 ENST00000590545.5
TJP3
tight junction protein 3
chr10_-_61001430 0.16 ENST00000357917.4
RHOBTB1
Rho related BTB domain containing 1
chr14_-_67515153 0.16 ENST00000555994.6
TMEM229B
transmembrane protein 229B
chr8_+_54616078 0.16 ENST00000220676.2
RP1
RP1 axonemal microtubule associated
chrX_+_154541193 0.15 ENST00000440286.5
IKBKG
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chrX_+_41447322 0.15 ENST00000378220.2
ENST00000342595.2
NYX
nyctalopin
chr22_+_29268248 0.15 ENST00000436425.5
ENST00000447973.5
ENST00000397938.7
ENST00000406548.5
ENST00000437155.6
ENST00000415761.5
ENST00000331029.11
EWSR1
EWS RNA binding protein 1
chr15_+_64460728 0.15 ENST00000416172.1
ZNF609
zinc finger protein 609
chr10_+_127987271 0.15 ENST00000471218.5
PTPRE
protein tyrosine phosphatase receptor type E
chr7_+_117020191 0.15 ENST00000434836.5
ENST00000393443.5
ENST00000465133.5
ENST00000477742.5
ENST00000393444.7
ENST00000393447.8
ST7
suppression of tumorigenicity 7
chr14_+_58427686 0.15 ENST00000650904.1
ENST00000652326.2
ENST00000554463.5
ENST00000555833.5
KIAA0586
KIAA0586
chr22_-_38084093 0.15 ENST00000681075.1
SLC16A8
solute carrier family 16 member 8
chr1_+_156147350 0.14 ENST00000435124.5
ENST00000633494.1
SEMA4A
semaphorin 4A
chr4_+_107894242 0.14 ENST00000503385.1
SGMS2
sphingomyelin synthase 2
chr4_-_101347492 0.14 ENST00000394854.8
PPP3CA
protein phosphatase 3 catalytic subunit alpha
chr7_+_130207847 0.14 ENST00000297819.4
SSMEM1
serine rich single-pass membrane protein 1
chr9_+_2015335 0.14 ENST00000636559.1
ENST00000349721.8
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_+_150508110 0.14 ENST00000261797.7
NDST1
N-deacetylase and N-sulfotransferase 1
chr1_-_160343235 0.13 ENST00000368069.7
ENST00000241704.8
ENST00000647683.1
ENST00000649787.1
COPA
COPI coat complex subunit alpha

Network of associatons between targets according to the STRING database.

First level regulatory network of GSC_GSC2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0008078 mesodermal cell migration(GO:0008078) axial mesoderm morphogenesis(GO:0048319)
0.3 3.4 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.3 4.6 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.3 1.8 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.3 0.8 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.3 0.8 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 3.0 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.2 0.9 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 0.7 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 0.9 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 2.0 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 0.7 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.2 4.7 GO:0071420 cellular response to histamine(GO:0071420)
0.2 1.4 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.7 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.7 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.4 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 1.3 GO:0055048 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 1.0 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.5 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.6 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 1.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.9 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.3 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 1.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.9 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:0016119 carotene metabolic process(GO:0016119)
0.1 0.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.3 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 1.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.3 GO:0036269 swimming behavior(GO:0036269)
0.1 0.4 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.3 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.2 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.1 4.3 GO:0010107 potassium ion import(GO:0010107)
0.1 3.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.3 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.4 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.4 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 1.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.5 GO:2000576 positive regulation of microtubule motor activity(GO:2000576)
0.0 2.4 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.8 GO:0046548 retinal rod cell development(GO:0046548)
0.0 1.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 1.0 GO:0015671 oxygen transport(GO:0015671)
0.0 1.0 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.8 GO:0007097 nuclear migration(GO:0007097)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.3 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.6 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.9 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 1.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 1.0 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 2.5 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.6 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 1.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 2.8 GO:0007286 spermatid development(GO:0007286)
0.0 0.9 GO:0003091 renal water homeostasis(GO:0003091)
0.0 0.3 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0032127 dense core granule membrane(GO:0032127)
0.3 0.8 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 0.9 GO:0035841 new growing cell tip(GO:0035841)
0.1 1.3 GO:0055028 cortical microtubule(GO:0055028)
0.1 4.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 2.5 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.0 GO:0034709 methylosome(GO:0034709)
0.1 0.8 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 1.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.7 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.6 GO:0005883 neurofilament(GO:0005883)
0.0 4.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 4.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 1.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.8 GO:0005901 caveola(GO:0005901)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 2.2 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.6 GO:0042835 BRE binding(GO:0042835)
0.4 2.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.4 3.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.3 4.7 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.3 0.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.2 0.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 0.7 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 3.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.0 GO:0044020 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 1.8 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.6 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.3 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.8 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 3.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.4 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 1.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 0.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.3 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.3 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 3.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0031404 chloride ion binding(GO:0031404)
0.0 1.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 1.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 1.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.3 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.6 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 1.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 4.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 2.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 2.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 5.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.5 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 4.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 2.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.7 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.9 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 2.7 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 3.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 1.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.8 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling