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Illumina Body Map 2 (GSE30611)
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Results for GUAGUGU
Z-value: 0.81
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miRNA associated with seed GUAGUGU
| Name | miRBASE accession |
|---|---|
|
hsa-miR-142-3p.1
|
MIMAT0000434 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr21_-_43427131 Show fit | 2.46 |
ENST00000270162.8
|
salt inducible kinase 1 |
|
| chr5_+_42423433 Show fit | 1.81 |
ENST00000230882.9
|
growth hormone receptor |
|
| chr5_-_91383310 Show fit | 1.78 |
ENST00000265138.4
|
arrestin domain containing 3 |
|
| chr12_+_122078740 Show fit | 1.73 |
ENST00000319080.12
|
MLX interacting protein |
|
| chr4_+_86934976 Show fit | 1.53 |
ENST00000507468.5
ENST00000395146.9 |
AF4/FMR2 family member 1 |
|
| chr11_+_111602380 Show fit | 1.40 |
ENST00000304987.4
|
salt inducible kinase 2 |
|
| chr4_+_38867789 Show fit | 1.38 |
ENST00000358869.5
|
family with sequence similarity 114 member A1 |
|
| chr19_-_17245889 Show fit | 1.38 |
ENST00000291442.4
|
nuclear receptor subfamily 2 group F member 6 |
|
| chr11_+_34621065 Show fit | 1.35 |
ENST00000257831.8
|
ETS homologous factor |
|
| chr16_-_4116403 Show fit | 1.32 |
ENST00000294016.8
|
adenylate cyclase 9 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GUAGUGU
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.5 | GO:0010868 | negative regulation of triglyceride biosynthetic process(GO:0010868) |
| 0.0 | 2.0 | GO:0009649 | entrainment of circadian clock(GO:0009649) |
| 0.3 | 1.8 | GO:0071879 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
| 0.2 | 1.8 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 0.0 | 1.4 | GO:0046626 | regulation of insulin receptor signaling pathway(GO:0046626) |
| 0.2 | 1.3 | GO:0035947 | regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) |
| 0.1 | 1.3 | GO:0097011 | cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012) |
| 0.0 | 1.3 | GO:0071880 | adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880) |
| 0.0 | 1.3 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.0 | 1.2 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 1.8 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 0.0 | 1.4 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 1.3 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 1.3 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.2 | 1.1 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) |
| 0.2 | 0.7 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.1 | 0.6 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.0 | 0.6 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.0 | 0.6 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 0.6 | GO:0005677 | chromatin silencing complex(GO:0005677) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.5 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 1.8 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
| 0.0 | 1.6 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 1.4 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.1 | 1.3 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.0 | 1.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 1.2 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.0 | 1.2 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.0 | 1.2 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.2 | 1.1 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.6 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 1.8 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.8 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 1.6 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 1.3 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 1.0 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 1.0 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.9 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 0.4 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 0.2 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 2.0 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 1.8 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.1 | 1.3 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.1 | 1.2 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.0 | 1.2 | REACTOME PIP3 ACTIVATES AKT SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.0 | 1.0 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 1.0 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 0.7 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.0 | 0.7 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |