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Illumina Body Map 2 (GSE30611)
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Results for GUCAGUU
Z-value: 0.32
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miRNA associated with seed GUCAGUU
| Name | miRBASE accession |
|---|---|
|
hsa-miR-223-3p
|
MIMAT0000280 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_-_13938618 Show fit | 1.07 |
ENST00000454189.6
|
glycoprotein M6B |
|
| chr1_+_65264694 Show fit | 0.92 |
ENST00000263441.11
ENST00000395325.7 |
DnaJ heat shock protein family (Hsp40) member C6 |
|
| chr9_-_19786928 Show fit | 0.92 |
ENST00000341998.6
ENST00000286344.3 |
solute carrier family 24 member 2 |
|
| chr4_-_98658582 Show fit | 0.72 |
ENST00000305798.8
|
tetraspanin 5 |
|
| chr18_+_74534594 Show fit | 0.66 |
ENST00000582365.1
|
carnosine dipeptidase 1 |
|
| chr5_+_72107453 Show fit | 0.66 |
ENST00000296755.12
ENST00000511641.2 |
microtubule associated protein 1B |
|
| chr1_-_94541746 Show fit | 0.66 |
ENST00000334047.12
|
coagulation factor III, tissue factor |
|
| chr4_-_152536045 Show fit | 0.65 |
ENST00000603548.6
ENST00000281708.10 |
F-box and WD repeat domain containing 7 |
|
| chr1_-_40665654 Show fit | 0.61 |
ENST00000372684.8
|
regulating synaptic membrane exocytosis 3 |
|
| chr2_+_79512993 Show fit | 0.59 |
ENST00000496558.5
ENST00000451966.5 ENST00000402739.9 ENST00000629316.2 |
catenin alpha 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GUCAGUU
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.5 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.1 | 0.9 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.0 | 0.9 | GO:0060292 | long term synaptic depression(GO:0060292) |
| 0.0 | 0.8 | GO:0061162 | establishment of monopolar cell polarity(GO:0061162) |
| 0.2 | 0.7 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 0.2 | 0.7 | GO:2000638 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 0.0 | 0.7 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.0 | 0.6 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 0.0 | 0.6 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.0 | 0.6 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.7 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.0 | 0.7 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.0 | 0.4 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 0.3 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 0.2 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.0 | 0.2 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
| 0.0 | 0.2 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.0 | 0.1 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 0.0 | 0.1 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.0 | 0.1 | GO:0072559 | NLRP3 inflammasome complex(GO:0072559) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.1 | 0.7 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.0 | 0.7 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.1 | 0.5 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.1 | 0.4 | GO:0004356 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
| 0.1 | 0.4 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.1 | 0.4 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.0 | 0.4 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 0.2 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.0 | 0.2 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.7 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 0.7 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.2 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 0.8 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.7 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.0 | 0.5 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 0.4 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 0.2 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |