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Illumina Body Map 2 (GSE30611)

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Results for GZF1

Z-value: 0.92

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Transcription factors associated with GZF1

Gene Symbol Gene ID Gene Info
ENSG00000125812.16 GDNF inducible zinc finger protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GZF1hg38_v1_chr20_+_23362144_233623200.038.8e-01Click!

Activity profile of GZF1 motif

Sorted Z-values of GZF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_33080445 4.02 ENST00000428835.5
major histocompatibility complex, class II, DP beta 1
chr1_+_26280059 3.76 ENST00000270792.10
SH3 domain binding glutamate rich protein like 3
chr6_-_33080767 3.60 ENST00000453337.1
ENST00000417724.1
major histocompatibility complex, class II, DP alpha 1
chr1_+_26280117 3.46 ENST00000319041.6
SH3 domain binding glutamate rich protein like 3
chr6_-_33080710 3.46 ENST00000419277.5
major histocompatibility complex, class II, DP alpha 1
chr7_-_27143672 3.02 ENST00000222726.4
homeobox A5
chr3_-_86991135 2.78 ENST00000398399.7
vestigial like family member 3
chr1_+_9651723 2.76 ENST00000377346.9
ENST00000536656.5
ENST00000628140.2
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr3_+_30606574 2.58 ENST00000295754.10
ENST00000359013.4
transforming growth factor beta receptor 2
chr6_-_41940537 2.01 ENST00000512426.5
cyclin D3
chr5_+_119268689 1.98 ENST00000274456.6
TNF alpha induced protein 8
chr7_-_26864573 1.90 ENST00000345317.7
src kinase associated phosphoprotein 2
chr6_-_36547400 1.86 ENST00000229812.8
serine/threonine kinase 38
chr1_+_32292067 1.48 ENST00000373548.8
ENST00000428704.1
histone deacetylase 1
chr8_-_41309434 1.42 ENST00000220772.8
secreted frizzled related protein 1
chr4_-_146521891 1.38 ENST00000394059.8
ENST00000502607.1
ENST00000335472.12
ENST00000432059.6
solute carrier family 10 member 7
chr3_-_79767987 1.36 ENST00000464233.6
roundabout guidance receptor 1
chr6_-_42451261 1.33 ENST00000372917.8
ENST00000340840.6
ENST00000354325.2
transcriptional regulating factor 1
chr21_+_45074549 1.32 ENST00000348831.9
ENST00000437626.5
ENST00000389863.8
adenosine deaminase RNA specific B1
chr19_+_35666515 1.30 ENST00000617999.4
ENST00000616789.4
uroplakin 1A
chr11_+_102047422 1.29 ENST00000434758.7
ENST00000526781.5
ENST00000534360.1
cilia and flagella associated protein 300
chr1_-_120051714 1.29 ENST00000579475.7
notch receptor 2
chr10_-_102120246 1.26 ENST00000425280.2
LIM domain binding 1
chr4_+_26343156 1.23 ENST00000680928.1
ENST00000681260.1
recombination signal binding protein for immunoglobulin kappa J region
chr5_+_119268744 1.23 ENST00000388882.5
TNF alpha induced protein 8
chr19_-_51646800 1.19 ENST00000599649.5
ENST00000429354.3
ENST00000360844.6
sialic acid binding Ig like lectin 5
sialic acid binding Ig like lectin 14
chr1_+_78649818 1.17 ENST00000370747.9
ENST00000438486.1
interferon induced protein 44
chr17_-_31321743 1.16 ENST00000247270.3
ecotropic viral integration site 2A
chr19_+_926001 1.16 ENST00000263620.8
AT-rich interaction domain 3A
chr16_+_67842277 1.14 ENST00000303596.3
THAP domain containing 11
chr19_-_51630401 1.14 ENST00000683636.1
sialic acid binding Ig like lectin 5
chr3_-_86990511 1.08 ENST00000494229.1
vestigial like family member 3
chr10_-_102120318 1.05 ENST00000673968.1
LIM domain binding 1
chr3_-_86991109 1.03 ENST00000383698.3
vestigial like family member 3
chr14_-_52069039 0.95 ENST00000216286.10
nidogen 2
chr5_+_171387757 0.92 ENST00000677297.1
ENST00000521672.6
ENST00000679190.1
ENST00000351986.10
ENST00000676589.1
ENST00000679233.1
ENST00000677357.1
ENST00000296930.10
ENST00000393820.2
ENST00000523622.1
nucleophosmin 1
chr7_-_93890160 0.89 ENST00000451238.1
tissue factor pathway inhibitor 2
chr14_-_52069228 0.89 ENST00000617139.4
nidogen 2
chr4_-_47463649 0.82 ENST00000381571.6
COMM domain containing 8
chr19_-_3786254 0.79 ENST00000585778.5
megakaryocyte-associated tyrosine kinase
chr11_+_65572349 0.76 ENST00000316409.2
ENST00000449319.2
ENST00000530349.2
family with sequence similarity 89 member B
chrX_+_153972729 0.75 ENST00000369982.5
transmembrane protein 187
chr4_-_146521666 0.73 ENST00000507030.5
solute carrier family 10 member 7
chr19_-_58573280 0.67 ENST00000594234.5
ENST00000596039.1
ENST00000215057.7
myeloid zinc finger 1
chr14_-_53153098 0.66 ENST00000612692.4
ENST00000395606.5
DDHD domain containing 1
chr14_+_49620750 0.66 ENST00000305386.4
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chr6_+_30557274 0.61 ENST00000376557.3
proline rich 3
chr4_+_26343132 0.55 ENST00000515573.5
recombination signal binding protein for immunoglobulin kappa J region
chr19_-_58573555 0.54 ENST00000599369.5
myeloid zinc finger 1
chr12_-_120224695 0.52 ENST00000552550.5
paxillin
chr6_+_30557287 0.52 ENST00000376560.8
proline rich 3
chr9_-_14307928 0.49 ENST00000637640.1
ENST00000493697.1
ENST00000636057.1
nuclear factor I B
chr14_-_31457417 0.49 ENST00000356180.4
D-aminoacyl-tRNA deacylase 2
chr1_-_41918666 0.47 ENST00000372584.5
HIVEP zinc finger 3
chr7_-_6706843 0.44 ENST00000394917.3
ENST00000342651.9
ENST00000405858.6
zinc finger protein 12
chrX_+_153972769 0.42 ENST00000425274.1
transmembrane protein 187
chr14_-_53153281 0.40 ENST00000357758.3
ENST00000673822.2
DDHD domain containing 1
chr5_-_113294895 0.40 ENST00000514701.5
ENST00000302475.8
MCC regulator of WNT signaling pathway
chr19_-_3786363 0.39 ENST00000310132.11
megakaryocyte-associated tyrosine kinase
chr1_-_41918858 0.38 ENST00000372583.6
HIVEP zinc finger 3
chr20_-_32743406 0.36 ENST00000474815.2
ENST00000446419.6
ENST00000278980.11
ENST00000642484.1
ENST00000646357.1
COMM domain containing 7
novel protein
chr22_-_42959852 0.35 ENST00000402229.5
ENST00000407585.5
ENST00000453079.1
protein kinase C and casein kinase substrate in neurons 2
chr12_-_102120065 0.35 ENST00000552283.6
ENST00000551744.2
nucleoporin 37
chr16_+_1612337 0.32 ENST00000674071.1
ENST00000397412.8
cramped chromatin regulator homolog 1
chr1_-_32336224 0.28 ENST00000329421.8
MARCKS like 1
chr12_+_102120172 0.24 ENST00000327680.7
ENST00000541394.5
ENST00000543784.5
PARP1 binding protein
chr16_+_86578543 0.23 ENST00000320241.5
forkhead box L1
chr14_-_31457495 0.22 ENST00000310850.9
D-aminoacyl-tRNA deacylase 2
chr7_+_102363874 0.20 ENST00000496391.5
PRKR interacting protein 1
chr19_-_3786408 0.20 ENST00000395040.6
megakaryocyte-associated tyrosine kinase
chr17_-_38748184 0.18 ENST00000618941.4
ENST00000620225.5
ENST00000618506.1
ENST00000616129.4
polycomb group ring finger 2
chr3_+_51671175 0.16 ENST00000614067.4
ENST00000457573.5
ENST00000611400.4
ENST00000412249.5
ENST00000425781.5
ENST00000341333.10
ENST00000415259.5
ENST00000395057.5
ENST00000416589.5
testis expressed 264, ER-phagy receptor
chrX_+_54809060 0.15 ENST00000396224.1
MAGE family member D2
chr7_-_81769971 0.13 ENST00000354224.10
ENST00000643024.1
hepatocyte growth factor
chr19_-_43880142 0.12 ENST00000324394.7
zinc finger protein 404
chr10_-_125161019 0.12 ENST00000411419.6
C-terminal binding protein 2
chr16_-_1611985 0.10 ENST00000426508.7
intraflagellar transport 140
chr10_+_92593112 0.10 ENST00000260731.5
kinesin family member 11
chr14_-_21511290 0.07 ENST00000298717.9
methyltransferase like 3
chr10_+_96000091 0.04 ENST00000424464.5
ENST00000410012.6
ENST00000344386.3
coiled-coil and C2 domain containing 2B
chr7_+_5045821 0.04 ENST00000353796.7
ENST00000396912.2
ENST00000396904.2
RB associated KRAB zinc finger
RBAK-RBAKDN readthrough
chrX_+_81202066 0.01 ENST00000373212.6
SH3 domain binding glutamate rich protein like

Network of associatons between targets according to the STRING database.

First level regulatory network of GZF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0060434 bronchus morphogenesis(GO:0060434)
0.8 2.3 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.8 3.0 GO:0060435 bronchiole development(GO:0060435)
0.6 2.8 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.5 1.4 GO:0014034 neural crest cell fate commitment(GO:0014034) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.3 1.3 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.3 0.8 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 1.4 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.2 1.5 GO:0061198 fungiform papilla formation(GO:0061198)
0.2 1.8 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.9 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.1 11.1 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.1 1.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 1.3 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.1 7.2 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.0 0.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 1.8 GO:0071711 basement membrane organization(GO:0071711)
0.0 2.0 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.4 GO:0070836 caveola assembly(GO:0070836)
0.0 0.5 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.8 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:1904688 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.9 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 3.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 1.9 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 1.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 2.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 2.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 2.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 2.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 8.1 GO:0030027 lamellipodium(GO:0030027)
0.0 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.4 7.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 7.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 2.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2 0.7 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.2 2.3 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 1.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 4.0 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.3 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 1.8 GO:0000150 recombinase activity(GO:0000150)
0.1 0.9 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 3.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 2.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 1.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 2.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 1.8 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 3.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 11.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 3.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 2.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 2.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination