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Illumina Body Map 2 (GSE30611)

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Results for HAND1

Z-value: 1.03

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Transcription factors associated with HAND1

Gene Symbol Gene ID Gene Info
HAND1
ENSG00000113196.3 heart and neural crest derivatives expressed 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HAND1hg38_v1_chr5_-_154478218_154478234-0.183.3e-01Click!

Activity profile of HAND1 motif

Sorted Z-values of HAND1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_52803807 4.02 ENST00000334575.6
GSTA1
glutathione S-transferase alpha 1
chr14_-_64942720 3.37 ENST00000557049.1
ENST00000389614.6
GPX2
glutathione peroxidase 2
chr6_+_133889105 3.13 ENST00000367882.5
TCF21
transcription factor 21
chr14_-_64942783 2.76 ENST00000612794.1
GPX2
glutathione peroxidase 2
chr2_-_27495185 2.75 ENST00000264703.4
FNDC4
fibronectin type III domain containing 4
chr16_-_31135699 2.66 ENST00000317508.11
ENST00000568261.5
ENST00000567797.1
PRSS8
serine protease 8
chr17_-_66220630 2.66 ENST00000585162.1
APOH
apolipoprotein H
chr12_+_40692413 2.38 ENST00000551295.7
ENST00000547702.5
ENST00000551424.5
CNTN1
contactin 1
chr17_+_47831608 2.38 ENST00000269025.9
LRRC46
leucine rich repeat containing 46
chr2_+_209579598 2.17 ENST00000445941.5
ENST00000673860.1
MAP2
microtubule associated protein 2
chr2_+_209579399 2.14 ENST00000360351.8
MAP2
microtubule associated protein 2
chr2_+_227813834 2.13 ENST00000358813.5
ENST00000409189.7
CCL20
C-C motif chemokine ligand 20
chr7_-_81770039 1.96 ENST00000222390.11
ENST00000453411.6
ENST00000457544.7
ENST00000444829.7
HGF
hepatocyte growth factor
chr11_-_5243644 1.91 ENST00000643122.1
HBD
hemoglobin subunit delta
chr20_+_59721210 1.91 ENST00000395636.6
ENST00000361300.4
PHACTR3
phosphatase and actin regulator 3
chr17_+_39628496 1.90 ENST00000394265.5
ENST00000394267.2
PPP1R1B
protein phosphatase 1 regulatory inhibitor subunit 1B
chr19_+_35868585 1.90 ENST00000652533.1
APLP1
amyloid beta precursor like protein 1
chr19_+_35868518 1.88 ENST00000221891.9
APLP1
amyloid beta precursor like protein 1
chr7_-_117323041 1.66 ENST00000491214.1
ENST00000265441.8
WNT2
Wnt family member 2
chr11_-_63563370 1.56 ENST00000255695.2
PLAAT2
phospholipase A and acyltransferase 2
chr2_+_209579429 1.51 ENST00000361559.8
MAP2
microtubule associated protein 2
chr1_+_202122910 1.50 ENST00000682545.1
ENST00000367282.6
ENST00000682887.1
GPR37L1
G protein-coupled receptor 37 like 1
chr20_+_46029165 1.40 ENST00000616201.4
ENST00000616202.4
ENST00000616933.4
ENST00000626937.2
SLC12A5
solute carrier family 12 member 5
chr7_-_81770122 1.39 ENST00000423064.7
HGF
hepatocyte growth factor
chr2_+_209579315 1.35 ENST00000392193.5
MAP2
microtubule associated protein 2
chr16_-_31135640 1.33 ENST00000567531.5
PRSS8
serine protease 8
chr7_+_73827737 1.29 ENST00000435050.1
CLDN4
claudin 4
chr19_-_10102659 1.27 ENST00000592641.5
ENST00000253109.5
ANGPTL6
angiopoietin like 6
chr9_-_97938157 1.26 ENST00000616898.2
HEMGN
hemogen
chr11_-_62709633 1.23 ENST00000532818.5
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin
chr6_-_132798587 1.23 ENST00000275227.9
SLC18B1
solute carrier family 18 member B1
chr1_+_27392612 1.22 ENST00000374024.4
GPR3
G protein-coupled receptor 3
chr1_+_65309517 1.22 ENST00000371069.5
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6
chr7_-_81770013 1.20 ENST00000465234.2
HGF
hepatocyte growth factor
chr1_+_207089233 1.20 ENST00000243611.9
ENST00000367076.7
C4BPB
complement component 4 binding protein beta
chr15_+_74217189 1.15 ENST00000635913.1
CCDC33
coiled-coil domain containing 33
chr1_+_202122881 1.13 ENST00000683302.1
ENST00000683557.1
GPR37L1
G protein-coupled receptor 37 like 1
chr22_+_24603147 1.13 ENST00000412658.5
ENST00000445029.5
ENST00000400382.6
ENST00000419133.5
ENST00000438643.6
ENST00000452551.5
ENST00000412898.5
ENST00000400380.5
ENST00000455483.5
ENST00000430289.5
GGT1
gamma-glutamyltransferase 1
chr8_+_30744150 1.12 ENST00000265616.10
ENST00000341403.9
ENST00000615729.4
UBXN8
UBX domain protein 8
chr11_-_62709841 1.10 ENST00000464544.1
ENST00000530009.1
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin
chr1_+_207089195 1.08 ENST00000452902.6
C4BPB
complement component 4 binding protein beta
chr3_+_112333147 1.05 ENST00000473539.5
ENST00000315711.12
ENST00000383681.7
CD200
CD200 molecule
chr1_+_207088825 1.04 ENST00000367078.8
C4BPB
complement component 4 binding protein beta
chrX_+_71144818 1.04 ENST00000536169.5
ENST00000358741.4
ENST00000395855.6
ENST00000374051.7
NLGN3
neuroligin 3
chr1_+_207089283 1.03 ENST00000391923.1
C4BPB
complement component 4 binding protein beta
chr19_+_4304588 0.95 ENST00000221856.11
FSD1
fibronectin type III and SPRY domain containing 1
chr4_+_41612892 0.93 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIMCH1
LIM and calponin homology domains 1
chr7_-_81769971 0.89 ENST00000354224.10
ENST00000643024.1
HGF
hepatocyte growth factor
chr6_+_43132472 0.84 ENST00000489707.5
PTK7
protein tyrosine kinase 7 (inactive)
chr11_+_101914997 0.83 ENST00000263468.13
CEP126
centrosomal protein 126
chr2_-_196926670 0.83 ENST00000354764.9
PGAP1
post-GPI attachment to proteins inositol deacylase 1
chr10_-_71719772 0.81 ENST00000441508.4
C10orf105
chromosome 10 open reading frame 105
chr15_-_76012390 0.80 ENST00000394907.8
NRG4
neuregulin 4
chr7_-_20217342 0.80 ENST00000400331.10
ENST00000332878.8
MACC1
MET transcriptional regulator MACC1
chr10_+_125973373 0.80 ENST00000417114.5
ENST00000445510.5
ENST00000368691.5
FANK1
fibronectin type III and ankyrin repeat domains 1
chr16_-_28597042 0.77 ENST00000533150.5
ENST00000335715.9
SULT1A2
sulfotransferase family 1A member 2
chr3_+_112332500 0.77 ENST00000606471.5
CD200
CD200 molecule
chr18_+_58045642 0.76 ENST00000676223.1
ENST00000675147.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr1_-_101996919 0.75 ENST00000370103.9
OLFM3
olfactomedin 3
chr7_-_151057848 0.75 ENST00000297518.4
CDK5
cyclin dependent kinase 5
chr7_-_81770428 0.75 ENST00000421558.1
HGF
hepatocyte growth factor
chr16_-_28610032 0.74 ENST00000567512.1
SULT1A1
sulfotransferase family 1A member 1
chr3_+_130581741 0.74 ENST00000511332.1
COL6A6
collagen type VI alpha 6 chain
chr12_-_62260123 0.70 ENST00000552075.5
TAFA2
TAFA chemokine like family member 2
chr12_-_25648544 0.70 ENST00000540106.5
ENST00000445693.5
ENST00000545543.1
LMNTD1
lamin tail domain containing 1
chr16_-_28609992 0.69 ENST00000314752.11
SULT1A1
sulfotransferase family 1A member 1
chr2_-_158380960 0.68 ENST00000409187.5
CCDC148
coiled-coil domain containing 148
chr6_+_123803853 0.68 ENST00000368417.6
NKAIN2
sodium/potassium transporting ATPase interacting 2
chr12_-_52814106 0.67 ENST00000551956.2
KRT4
keratin 4
chr18_+_58045683 0.67 ENST00000592846.5
ENST00000675801.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chrX_+_150363306 0.66 ENST00000370401.7
ENST00000432680.7
MAMLD1
mastermind like domain containing 1
chr3_+_46877705 0.66 ENST00000449590.6
PTH1R
parathyroid hormone 1 receptor
chr20_-_1184981 0.66 ENST00000429036.2
TMEM74B
transmembrane protein 74B
chr7_-_151057880 0.65 ENST00000485972.6
CDK5
cyclin dependent kinase 5
chr16_-_28609976 0.64 ENST00000566189.5
SULT1A1
sulfotransferase family 1A member 1
chr7_-_81770362 0.64 ENST00000412881.5
HGF
hepatocyte growth factor
chr3_-_9769910 0.62 ENST00000256460.8
CAMK1
calcium/calmodulin dependent protein kinase I
chr6_-_39314412 0.59 ENST00000373231.9
KCNK17
potassium two pore domain channel subfamily K member 17
chr6_+_11093753 0.59 ENST00000416247.4
SMIM13
small integral membrane protein 13
chr17_-_74623730 0.59 ENST00000392619.2
CD300E
CD300e molecule
chr19_+_38304105 0.57 ENST00000588605.5
ENST00000301246.10
C19orf33
chromosome 19 open reading frame 33
chr5_+_36608146 0.56 ENST00000381918.4
ENST00000513646.1
SLC1A3
solute carrier family 1 member 3
chr10_-_102451536 0.56 ENST00000625129.1
C10orf95
chromosome 10 open reading frame 95
chr4_-_40629842 0.55 ENST00000295971.12
RBM47
RNA binding motif protein 47
chr7_+_99408609 0.55 ENST00000403633.6
BUD31
BUD31 homolog
chr10_+_5048748 0.54 ENST00000602997.5
ENST00000439082.7
AKR1C3
aldo-keto reductase family 1 member C3
chr7_-_142885737 0.53 ENST00000359396.9
ENST00000436401.1
TRPV6
transient receptor potential cation channel subfamily V member 6
chrX_+_150363258 0.52 ENST00000683696.1
MAMLD1
mastermind like domain containing 1
chr2_-_42361149 0.49 ENST00000468711.5
ENST00000463055.1
COX7A2L
cytochrome c oxidase subunit 7A2 like
chr2_-_196926717 0.49 ENST00000409475.5
ENST00000374738.3
PGAP1
post-GPI attachment to proteins inositol deacylase 1
chr18_-_46756791 0.49 ENST00000538168.5
ENST00000536490.1
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr4_+_25160631 0.45 ENST00000510415.1
ENST00000507794.2
ENST00000512921.4
SEPSECS-AS1
PI4K2B
SEPSECS antisense RNA 1 (head to head)
phosphatidylinositol 4-kinase type 2 beta
chr4_-_25160375 0.45 ENST00000382103.7
SEPSECS
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr1_+_174877430 0.45 ENST00000392064.6
RABGAP1L
RAB GTPase activating protein 1 like
chr17_+_38428456 0.44 ENST00000622683.5
ENST00000620417.4
ARHGAP23
Rho GTPase activating protein 23
chr4_+_41612702 0.42 ENST00000509277.5
LIMCH1
LIM and calponin homology domains 1
chr7_+_111091006 0.42 ENST00000451085.5
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr16_-_30031259 0.42 ENST00000380495.8
TLCD3B
TLC domain containing 3B
chr7_+_111091119 0.42 ENST00000308478.10
LRRN3
leucine rich repeat neuronal 3
chr3_+_147393718 0.42 ENST00000488404.5
ZIC1
Zic family member 1
chr20_+_46029009 0.42 ENST00000608944.5
SLC12A5
solute carrier family 12 member 5
chr1_-_167914089 0.42 ENST00000476818.2
ENST00000367848.1
ENST00000367851.9
ENST00000545172.5
ADCY10
adenylate cyclase 10
chr10_+_97584314 0.41 ENST00000370647.8
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr6_-_39314445 0.40 ENST00000453413.2
KCNK17
potassium two pore domain channel subfamily K member 17
chr4_-_40630588 0.38 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr17_+_45844875 0.36 ENST00000329196.7
SPPL2C
signal peptide peptidase like 2C
chr19_+_507487 0.36 ENST00000359315.6
TPGS1
tubulin polyglutamylase complex subunit 1
chr6_+_123804141 0.36 ENST00000368416.5
NKAIN2
sodium/potassium transporting ATPase interacting 2
chr1_-_53940100 0.36 ENST00000371376.1
HSPB11
heat shock protein family B (small) member 11
chr14_+_73616844 0.35 ENST00000381139.1
ACOT6
acyl-CoA thioesterase 6
chr5_+_144205250 0.33 ENST00000507359.3
KCTD16
potassium channel tetramerization domain containing 16
chr14_-_74426102 0.33 ENST00000554953.1
ENST00000331628.8
SYNDIG1L
synapse differentiation inducing 1 like
chr10_+_132036652 0.32 ENST00000657785.1
JAKMIP3
Janus kinase and microtubule interacting protein 3
chr2_+_201132769 0.32 ENST00000494258.5
CFLAR
CASP8 and FADD like apoptosis regulator
chr16_-_65072207 0.30 ENST00000562882.5
ENST00000567934.5
CDH11
cadherin 11
chr7_+_112450451 0.29 ENST00000429071.5
ENST00000403825.8
ENST00000675268.1
IFRD1
ENSG00000288634.1
interferon related developmental regulator 1
novel protein
chrX_-_34657274 0.29 ENST00000275954.4
TMEM47
transmembrane protein 47
chr12_-_56360084 0.29 ENST00000314128.9
ENST00000557235.5
ENST00000651915.1
STAT2
signal transducer and activator of transcription 2
chr4_-_103019634 0.28 ENST00000510559.1
ENST00000296422.12
ENST00000394789.7
SLC9B1
solute carrier family 9 member B1
chr6_-_36986122 0.28 ENST00000460219.2
ENST00000373627.10
ENST00000373616.9
MTCH1
mitochondrial carrier 1
chr4_-_25160546 0.27 ENST00000681948.1
SEPSECS
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr18_-_46757012 0.27 ENST00000315087.12
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr9_-_120793377 0.27 ENST00000684001.1
ENST00000684405.1
ENST00000608872.6
FBXW2
F-box and WD repeat domain containing 2
chr7_+_76510516 0.27 ENST00000257632.9
UPK3B
uroplakin 3B
chr12_+_25958891 0.26 ENST00000381352.7
ENST00000535907.5
ENST00000405154.6
ENST00000615708.4
RASSF8
Ras association domain family member 8
chr16_+_90022600 0.24 ENST00000620723.4
ENST00000268699.9
GAS8
growth arrest specific 8
chr17_+_7933080 0.23 ENST00000565740.5
CNTROB
centrobin, centriole duplication and spindle assembly protein
chrX_-_134796256 0.22 ENST00000486347.5
PABIR2
PABIR family member 2
chr19_-_12834548 0.21 ENST00000590404.6
ENST00000592204.5
ENST00000674343.2
RTBDN
retbindin
chr14_+_104138578 0.20 ENST00000423312.7
KIF26A
kinesin family member 26A
chr22_+_24607658 0.20 ENST00000451366.5
ENST00000428855.5
GGT1
gamma-glutamyltransferase 1
chr19_+_44662278 0.20 ENST00000622237.4
ENST00000618372.4
ENST00000619799.4
ENST00000592789.5
ENST00000591979.1
CEACAM19
CEA cell adhesion molecule 19
chr14_-_93207007 0.20 ENST00000556566.1
ENST00000306954.5
GON7
GON7 subunit of KEOPS complex
chr10_+_97584347 0.20 ENST00000370649.3
ENST00000370646.9
ENSG00000249967.1
HOGA1
novel protein
4-hydroxy-2-oxoglutarate aldolase 1
chr9_-_120793343 0.19 ENST00000684047.1
FBXW2
F-box and WD repeat domain containing 2
chr5_+_14441043 0.19 ENST00000639876.2
TRIO
trio Rho guanine nucleotide exchange factor
chr7_+_97005538 0.18 ENST00000518156.3
DLX6
distal-less homeobox 6
chr7_+_141790217 0.18 ENST00000247883.5
TAS2R5
taste 2 receptor member 5
chr19_-_40425982 0.17 ENST00000357949.5
SERTAD1
SERTA domain containing 1
chr2_-_42361198 0.16 ENST00000234301.3
COX7A2L
cytochrome c oxidase subunit 7A2 like
chrX_-_68433301 0.16 ENST00000680804.1
ENST00000680612.1
OPHN1
oligophrenin 1
chr1_-_155934398 0.15 ENST00000368320.7
ENST00000368321.8
KHDC4
KH domain containing 4, pre-mRNA splicing factor
chr3_+_124094663 0.14 ENST00000460856.5
ENST00000240874.7
KALRN
kalirin RhoGEF kinase
chr6_+_6588708 0.13 ENST00000230568.5
LY86
lymphocyte antigen 86
chr22_-_39532722 0.13 ENST00000334678.8
RPS19BP1
ribosomal protein S19 binding protein 1
chr6_+_101181254 0.11 ENST00000682090.1
ENST00000421544.6
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr10_-_5003850 0.11 ENST00000421196.7
ENST00000455190.2
ENST00000380753.8
AKR1C2
aldo-keto reductase family 1 member C2
chr4_+_41613476 0.11 ENST00000508466.1
LIMCH1
LIM and calponin homology domains 1
chr12_-_53335737 0.11 ENST00000303846.3
SP7
Sp7 transcription factor
chr1_+_43979179 0.10 ENST00000434555.7
ENST00000372324.6
ENST00000481924.2
B4GALT2
beta-1,4-galactosyltransferase 2
chr14_-_68793055 0.10 ENST00000439696.3
ZFP36L1
ZFP36 ring finger protein like 1
chr4_+_75556048 0.10 ENST00000616557.1
ENST00000435974.2
ENST00000311623.9
ODAPH
odontogenesis associated phosphoprotein
chr10_+_132036336 0.09 ENST00000668452.1
JAKMIP3
Janus kinase and microtubule interacting protein 3
chr11_-_26722051 0.08 ENST00000396005.8
SLC5A12
solute carrier family 5 member 12
chr10_+_101354028 0.08 ENST00000393441.8
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
chr21_+_33230073 0.08 ENST00000342101.7
ENST00000413881.5
ENST00000443073.5
IFNAR2
interferon alpha and beta receptor subunit 2
chr3_+_15601736 0.07 ENST00000303498.10
ENST00000417015.3
ENST00000672065.1
ENST00000672112.1
ENST00000643237.3
ENST00000672141.1
ENST00000646371.1
ENST00000672427.1
ENST00000672336.1
ENST00000673467.1
ENST00000672760.1
ENST00000437172.6
BTD
biotinidase
chr21_+_33229883 0.06 ENST00000382264.7
ENST00000342136.9
ENST00000404220.7
IFNAR2
interferon alpha and beta receptor subunit 2
chr6_-_87095059 0.06 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
CGA
glycoprotein hormones, alpha polypeptide
chr15_-_78811415 0.06 ENST00000388820.5
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif 7
chr19_+_18382163 0.05 ENST00000595973.2
GDF15
growth differentiation factor 15
chr11_+_111540273 0.05 ENST00000533999.5
LAYN
layilin
chr20_+_31368594 0.05 ENST00000253381.3
DEFB118
defensin beta 118
chr19_-_12835400 0.05 ENST00000591512.2
ENST00000587549.1
ENST00000322912.9
RTBDN
retbindin
chr19_+_55488404 0.04 ENST00000594321.5
ENST00000389623.11
SSC5D
scavenger receptor cysteine rich family member with 5 domains
chr4_-_40630739 0.03 ENST00000511902.5
ENST00000505220.1
RBM47
RNA binding motif protein 47
chr3_+_124094696 0.03 ENST00000360013.7
ENST00000684186.1
ENST00000684276.1
KALRN
kalirin RhoGEF kinase
chr9_+_70043840 0.03 ENST00000377182.5
MAMDC2
MAM domain containing 2
chr12_+_120694167 0.02 ENST00000535656.1
MLEC
malectin
chr6_-_117602447 0.02 ENST00000368498.7
ENST00000052569.10
ENST00000535237.2
GOPC
golgi associated PDZ and coiled-coil motif containing
chr10_+_80537902 0.02 ENST00000339284.6
ENST00000646907.2
SH2D4B
SH2 domain containing 4B
chr2_+_230996115 0.01 ENST00000424440.5
ENST00000452881.5
ENST00000433428.6
ENST00000455816.1
ENST00000440792.5
ENST00000423134.1
SPATA3
spermatogenesis associated 3
chr2_-_207167220 0.01 ENST00000421199.5
ENST00000457962.5
KLF7
Kruppel like factor 7
chr1_-_155934370 0.00 ENST00000368319.3
KHDC4
KH domain containing 4, pre-mRNA splicing factor

Network of associatons between targets according to the STRING database.

First level regulatory network of HAND1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.6 3.8 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.6 6.8 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.5 2.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.5 4.3 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.5 1.8 GO:0040040 thermosensory behavior(GO:0040040)
0.3 1.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.2 2.7 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.2 2.6 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.2 1.3 GO:0015798 myo-inositol transport(GO:0015798)
0.2 1.7 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.2 0.5 GO:0016487 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.2 0.7 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.2 1.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 0.6 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 1.9 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 4.0 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 1.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 2.8 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.3 GO:0007518 myoblast fate determination(GO:0007518)
0.1 1.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 1.8 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.1 1.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.1 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 6.0 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.1 2.3 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.5 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.6 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.8 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 7.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.6 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 1.3 GO:0015671 oxygen transport(GO:0015671)
0.0 6.1 GO:1990748 cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 1.3 GO:0061436 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) establishment of skin barrier(GO:0061436)
0.0 0.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.2 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.5 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.7 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.2 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.4 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.8 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 2.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.2 GO:0046959 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.0 0.3 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 1.0 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.6 GO:0042462 eye photoreceptor cell development(GO:0042462)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 1.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 2.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.9 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.7 GO:1990909 Wnt signalosome(GO:1990909)
0.1 4.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.4 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 6.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 4.3 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 3.1 GO:0005604 basement membrane(GO:0005604)
0.0 1.4 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.8 GO:0097546 ciliary base(GO:0097546)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 3.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0031696 alpha-2C adrenergic receptor binding(GO:0031696)
0.9 2.6 GO:0036505 prosaposin receptor activity(GO:0036505)
0.5 2.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.5 1.9 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.5 2.8 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.5 1.4 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.4 2.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.3 10.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 6.8 GO:0002162 dystroglycan binding(GO:0002162)
0.2 0.5 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.1 0.7 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 6.8 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.8 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.8 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 1.7 GO:0048018 receptor agonist activity(GO:0048018)
0.1 1.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 1.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 5.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 3.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.3 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 6.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 7.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 3.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.4 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 4.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 5.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 3.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 2.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 2.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 2.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides