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Illumina Body Map 2 (GSE30611)

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Results for HESX1

Z-value: 1.60

Motif logo

Transcription factors associated with HESX1

Gene Symbol Gene ID Gene Info
ENSG00000163666.10 HESX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HESX1hg38_v1_chr3_-_57226344_57226521-0.345.9e-02Click!

Activity profile of HESX1 motif

Sorted Z-values of HESX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_89117844 10.81 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr14_-_105940235 10.57 ENST00000390593.2
immunoglobulin heavy variable 6-1
chr2_+_89862438 9.83 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr2_-_88947820 9.80 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr2_+_89913982 9.70 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr2_-_89268506 9.35 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr2_-_89100352 8.84 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr2_+_90159840 7.97 ENST00000377032.5
immunoglobulin kappa variable 1D-12
chr2_-_89010515 7.20 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr2_-_89213917 7.16 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr14_-_106012390 6.47 ENST00000455737.2
immunoglobulin heavy variable 4-4
chr2_+_90154073 6.18 ENST00000611391.1
immunoglobulin kappa variable 1D-13
chr2_-_88966767 5.69 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr2_+_90220727 5.10 ENST00000471857.2
immunoglobulin kappa variable 1D-8
chrX_+_48676596 4.67 ENST00000450772.5
WASP actin nucleation promoting factor
chr11_-_118342691 4.52 ENST00000300692.9
CD3d molecule
chrX_+_136648138 4.19 ENST00000370629.7
CD40 ligand
chr2_-_88992903 4.18 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr5_+_40679907 4.14 ENST00000302472.4
prostaglandin E receptor 4
chr17_-_82317523 4.11 ENST00000583376.1
ENST00000578509.1
ENST00000584284.5
ENST00000582480.1
CD7 molecule
chr2_+_113406368 4.03 ENST00000453673.3
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chrX_+_136648214 3.67 ENST00000370628.2
CD40 ligand
chr14_-_105601728 3.37 ENST00000641420.1
ENST00000390541.2
immunoglobulin heavy constant epsilon
chr2_+_89884740 3.32 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chr11_+_67455352 3.03 ENST00000325656.7
calcium binding protein 4
chr2_+_90209873 2.99 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr2_-_89297785 2.84 ENST00000465170.1
immunoglobulin kappa variable 1-37 (non-functional)
chr19_-_45076465 2.63 ENST00000303809.7
zinc finger protein 296
chr1_-_205321737 2.60 ENST00000367157.6
NUAK family kinase 2
chr14_-_91836440 2.21 ENST00000340892.9
ENST00000360594.9
tandem C2 domains, nuclear
chr19_-_45076504 2.15 ENST00000622376.1
zinc finger protein 296
chr14_+_61187544 2.13 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
protein kinase C eta
chr14_-_24634160 2.12 ENST00000616551.1
ENST00000382542.5
ENST00000216341.9
ENST00000526004.1
ENST00000415355.7
granzyme B
chr4_+_153684241 2.11 ENST00000646219.1
ENST00000642580.1
ENST00000643501.1
ENST00000642700.2
toll like receptor 2
chr1_+_44800367 1.96 ENST00000372201.5
polo like kinase 3
chr14_+_22304051 1.93 ENST00000390466.1
T cell receptor alpha variable 39
chr6_-_41736239 1.89 ENST00000358871.6
transcription factor EB
chr14_-_91836526 1.86 ENST00000556018.5
tandem C2 domains, nuclear
chr17_-_63931354 1.76 ENST00000647774.1
novel protein
chr16_+_56961917 1.74 ENST00000379780.6
cholesteryl ester transfer protein
chr1_-_20119527 1.72 ENST00000375105.8
ENST00000617227.1
phospholipase A2 group IID
chr22_+_24424372 1.71 ENST00000464977.5
ENST00000444262.6
adenosine A2a receptor
chr17_+_63998344 1.65 ENST00000577953.5
ENST00000582540.5
ENST00000579184.5
ENST00000425164.7
ENST00000412177.6
ENST00000583891.5
ENST00000580752.1
proline rich 29
chr6_-_46735351 1.64 ENST00000274793.12
phospholipase A2 group VII
chr14_+_21846534 1.59 ENST00000390434.3
T cell receptor alpha variable 8-2
chr19_-_18086904 1.52 ENST00000322153.11
ENST00000593993.7
interleukin 12 receptor subunit beta 1
chr19_-_19628512 1.46 ENST00000588461.1
lysophosphatidic acid receptor 2
chr8_+_123072667 1.44 ENST00000519418.5
ENST00000287380.6
ENST00000327098.9
ENST00000522420.5
ENST00000521676.5
TBC1 domain family member 31
chr8_+_141391989 1.38 ENST00000520105.5
ENST00000523147.5
ENST00000521578.6
protein tyrosine phosphatase 4A3
chr2_+_240605417 1.29 ENST00000319838.10
ENST00000403859.1
G protein-coupled receptor 35
chr18_-_12883766 1.28 ENST00000645191.1
ENST00000646492.1
protein tyrosine phosphatase non-receptor type 2
chr7_-_47581631 1.27 ENST00000434451.1
tensin 3
chr19_-_19628197 1.22 ENST00000586703.1
ENST00000591042.1
ENST00000407877.8
lysophosphatidic acid receptor 2
chr17_+_30921935 1.20 ENST00000581285.5
ENST00000330889.8
ArfGAP with dual PH domains 2
chr20_-_63956382 1.18 ENST00000358711.7
ENST00000354216.11
uridine-cytidine kinase 1 like 1
chr14_-_24195334 1.17 ENST00000530563.1
ENST00000528895.5
ENST00000528669.5
ENST00000532632.1
ENST00000261789.9
transmembrane 9 superfamily member 1
chr2_+_219206768 1.14 ENST00000289528.10
ENST00000409206.5
ENST00000444522.6
ENST00000621130.4
ENST00000409594.5
ENST00000422255.5
ENST00000409412.5
ENST00000409097.5
ENST00000409336.5
ENST00000409217.5
zinc finger AN1-type containing 2B
chr9_-_128724088 1.14 ENST00000406904.2
ENST00000452105.5
ENST00000372667.9
ENST00000372663.9
zinc finger DHHC-type palmitoyltransferase 12
chr14_-_24634266 1.14 ENST00000382540.5
granzyme B
chr2_+_219206875 1.10 ENST00000409319.5
zinc finger AN1-type containing 2B
chr19_+_37907200 1.09 ENST00000222345.11
signal induced proliferation associated 1 like 3
chr12_-_46268989 1.08 ENST00000549049.5
ENST00000439706.5
ENST00000398637.10
solute carrier family 38 member 1
chr19_-_49867542 1.05 ENST00000600910.5
ENST00000322344.8
ENST00000600573.5
ENST00000596726.3
ENST00000638016.1
polynucleotide kinase 3'-phosphatase
chr10_-_43408787 1.02 ENST00000356053.7
heterogeneous nuclear ribonucleoprotein F
chr17_+_75093287 1.01 ENST00000538213.6
ENST00000584118.1
solute carrier family 16 member 5
chr4_-_143905529 1.01 ENST00000358615.9
ENST00000437468.2
glycophorin E (MNS blood group)
chr17_+_47209035 0.96 ENST00000572316.5
ENST00000354968.5
ENST00000576874.5
ENST00000536623.6
myosin light chain 4
chr7_+_142407663 0.95 ENST00000390367.3
T cell receptor beta variable 11-1
chr15_+_66453418 0.95 ENST00000566326.1
mitogen-activated protein kinase kinase 1
chr11_-_126268810 0.93 ENST00000332118.11
SRP receptor subunit alpha
chrX_+_153972729 0.92 ENST00000369982.5
transmembrane protein 187
chr14_+_45084093 0.92 ENST00000553605.1
ENST00000355765.11
pre-mRNA processing factor 39
chr7_+_100148890 0.91 ENST00000341942.9
ENST00000474141.5
ENST00000460732.5
ENST00000441173.1
ENST00000468582.5
ENST00000488241.5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr12_-_56630293 0.89 ENST00000546695.5
ENST00000549884.6
bromodomain adjacent to zinc finger domain 2A
chr19_-_49867251 0.88 ENST00000631020.2
ENST00000596014.5
ENST00000636994.1
polynucleotide kinase 3'-phosphatase
chr11_-_4393650 0.88 ENST00000254436.8
tripartite motif containing 21
chr2_-_43595963 0.87 ENST00000405006.8
THADA armadillo repeat containing
chr3_-_46693641 0.86 ENST00000415953.5
ALS2 C-terminal like
chr14_-_100376251 0.86 ENST00000556645.5
ENST00000556209.5
ENST00000556504.5
ENST00000556435.5
ENST00000554772.5
ENST00000553581.1
ENST00000553769.6
ENST00000554605.5
ENST00000557722.5
ENST00000553413.5
ENST00000553524.5
ENST00000358655.8
tryptophanyl-tRNA synthetase 1
chr17_+_49495286 0.86 ENST00000172229.8
nerve growth factor receptor
chr2_-_43595980 0.85 ENST00000403856.1
ENST00000404790.5
ENST00000405975.7
THADA armadillo repeat containing
chr12_-_54973547 0.80 ENST00000526532.5
ENST00000532757.5
thymocyte expressed, positive selection associated 1
chr12_+_103930600 0.77 ENST00000680316.1
ENST00000679861.1
heat shock protein 90 beta family member 1
chr14_+_20469399 0.75 ENST00000361505.10
ENST00000553591.1
purine nucleoside phosphorylase
chr20_+_37179310 0.75 ENST00000373632.8
ENST00000237530.11
ribophorin II
chr1_-_52553387 0.71 ENST00000484723.6
ENST00000524582.1
terminal uridylyl transferase 4
chr2_-_96265942 0.69 ENST00000432959.1
ENST00000258439.8
transmembrane protein 127
chr11_+_18394586 0.68 ENST00000227157.8
ENST00000478970.6
ENST00000495052.5
lactate dehydrogenase A
chr5_-_88883701 0.65 ENST00000636998.1
myocyte enhancer factor 2C
chr1_+_45550783 0.64 ENST00000621846.4
ENST00000434299.5
ENST00000351829.9
aldo-keto reductase family 1 member A1
chr1_-_26046111 0.63 ENST00000374278.7
ENST00000374276.4
solute carrier family 30 member 2
chr3_+_133574434 0.63 ENST00000508481.5
ENST00000420115.6
ENST00000504867.5
ENST00000507408.5
ENST00000511392.5
ENST00000515421.1
CDV3 homolog
chr20_+_37179109 0.62 ENST00000373622.9
ribophorin II
chr10_-_14548646 0.62 ENST00000378470.5
family with sequence similarity 107 member B
chr3_+_16265160 0.59 ENST00000627468.2
ENST00000605932.5
ENST00000435829.6
ENST00000285083.10
oxidoreductase NAD binding domain containing 1
chr12_-_120581361 0.59 ENST00000341039.6
ENST00000357500.5
POP5 homolog, ribonuclease P/MRP subunit
chr8_+_96261891 0.59 ENST00000517309.6
phosphatidylserine synthase 1
chr11_+_65181920 0.58 ENST00000279247.11
ENST00000532285.1
ENST00000534373.5
calpain 1
chr2_-_85602681 0.57 ENST00000334462.10
ENST00000306353.7
transmembrane protein 150A
chr12_-_46269105 0.57 ENST00000546893.5
solute carrier family 38 member 1
chr2_-_85602351 0.56 ENST00000409668.1
transmembrane protein 150A
chr16_-_84240012 0.55 ENST00000308251.6
potassium voltage-gated channel modifier subfamily G member 4
chr2_-_1744442 0.54 ENST00000433670.5
ENST00000425171.1
ENST00000252804.9
peroxidasin
chr16_+_21597204 0.52 ENST00000567404.5
methyltransferase like 9
chr2_-_37672448 0.52 ENST00000611976.1
CDC42 effector protein 3
chr8_+_145052447 0.49 ENST00000331434.7
ENST00000648531.1
ENST00000647640.1
ENST00000647724.1
ENST00000648784.1
chromosome 8 open reading frame 33
chr7_-_36985060 0.49 ENST00000396040.6
engulfment and cell motility 1
chr7_-_2555477 0.48 ENST00000340611.9
BRCA1 associated ATM activator 1
chr11_+_102347205 0.47 ENST00000532832.5
ENST00000530675.5
ENST00000227758.7
ENST00000533742.5
ENST00000532672.5
ENST00000531259.5
ENST00000527465.1
baculoviral IAP repeat containing 2
chr17_-_38853629 0.47 ENST00000378096.3
ENST00000479035.7
ENST00000394332.5
ENST00000394333.5
ENST00000577407.5
ribosomal protein L23
chr16_-_84239750 0.46 ENST00000568181.1
potassium voltage-gated channel modifier subfamily G member 4
chr12_-_53676314 0.45 ENST00000549164.5
ATP synthase membrane subunit c locus 2
chr17_+_19378476 0.44 ENST00000395604.8
ENST00000482850.1
mitogen-activated protein kinase 7
chr11_-_126268913 0.44 ENST00000532259.1
SRP receptor subunit alpha
chr1_+_45551031 0.44 ENST00000481885.5
ENST00000471651.1
aldo-keto reductase family 1 member A1
chr12_-_643620 0.43 ENST00000433832.2
ENST00000542920.1
ninjurin 2
chr9_+_129835442 0.43 ENST00000372429.8
ENST00000315480.9
ENST00000358355.5
ubiquitin specific peptidase 20
chr12_-_113471851 0.43 ENST00000261731.4
LIM homeobox 5
chr4_+_159282498 0.42 ENST00000514565.1
Rap guanine nucleotide exchange factor 2
chr9_-_127847117 0.42 ENST00000480266.5
endoglin
chr6_-_41921105 0.42 ENST00000434077.1
ENST00000409312.5
ENST00000265350.9
mediator complex subunit 20
chrX_+_153972769 0.42 ENST00000425274.1
transmembrane protein 187
chr11_-_66438788 0.42 ENST00000329819.4
ENST00000310999.11
ENST00000430466.6
mitochondrial ribosomal protein L11
chr7_+_101815904 0.41 ENST00000437600.9
ENST00000645010.1
ENST00000646649.1
cut like homeobox 1
chr12_+_123233420 0.41 ENST00000253233.6
ENST00000366329.7
ENST00000546132.2
ENST00000536130.2
chromosome 12 open reading frame 65
chr3_+_130929998 0.40 ENST00000508297.2
ATPase secretory pathway Ca2+ transporting 1
chr12_-_53676720 0.38 ENST00000673498.1
ATP synthase membrane subunit c locus 2
chr1_-_1232061 0.37 ENST00000660930.1
stromal cell derived factor 4
chr3_-_196968864 0.36 ENST00000443835.1
phosphatidylinositol glycan anchor biosynthesis class Z
chr1_-_1232031 0.35 ENST00000263741.12
stromal cell derived factor 4
chr10_-_45594491 0.35 ENST00000453980.3
membrane associated ring-CH-type finger 8
chr1_-_1231966 0.35 ENST00000360001.12
stromal cell derived factor 4
chr7_-_113118544 0.33 ENST00000397764.8
ENST00000441359.1
small integral membrane protein 30
chr19_+_11346556 0.33 ENST00000587531.5
coiled-coil domain containing 159
chr6_-_144008118 0.33 ENST00000629195.2
ENST00000650125.1
ENST00000647880.1
ENST00000649307.1
ENST00000674357.1
ENST00000417959.4
ENST00000635591.1
PLAG1 like zinc finger 1
hydatidiform mole associated and imprinted
chr1_+_1232214 0.33 ENST00000379198.5
beta-1,3-galactosyltransferase 6
chr14_-_70416973 0.33 ENST00000555276.5
ENST00000617124.4
cytochrome c oxidase assembly factor COX16
SYNJ2BP-COX16 readthrough
chr2_-_70717736 0.32 ENST00000415348.5
adducin 2
chr6_+_31971831 0.32 ENST00000375331.7
ENST00000375333.3
serine/threonine kinase 19
chr6_+_131573219 0.31 ENST00000356962.2
ENST00000368087.8
ENST00000673427.1
ENST00000640973.1
arginase 1
chr15_+_80072559 0.31 ENST00000560228.5
ENST00000559835.5
ENST00000559775.5
ENST00000558688.5
ENST00000560392.5
ENST00000560976.5
ENST00000558272.5
ENST00000558390.5
zinc finger AN1-type containing 6
chr19_+_19320817 0.31 ENST00000262815.13
ENST00000609122.5
MAU2 sister chromatid cohesion factor
chr2_+_134254065 0.30 ENST00000281923.4
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
chr10_-_45594760 0.30 ENST00000319836.7
membrane associated ring-CH-type finger 8
chr9_-_37904085 0.30 ENST00000377716.6
ENST00000242275.7
solute carrier family 25 member 51
chr6_-_41921081 0.29 ENST00000409060.1
mediator complex subunit 20
chr4_+_8580387 0.29 ENST00000382487.5
G protein-coupled receptor 78
chr10_-_99620401 0.28 ENST00000370495.6
solute carrier family 25 member 28
chr6_-_31170620 0.28 ENST00000638788.1
ENST00000259915.13
POU class 5 homeobox 1
chr11_-_57381146 0.27 ENST00000287143.2
proteoglycan 3, pro eosinophil major basic protein 2
chr6_+_26272923 0.27 ENST00000377733.4
H2B clustered histone 10
chr18_+_46917492 0.26 ENST00000592005.5
katanin catalytic subunit A1 like 2
chr6_+_85449584 0.26 ENST00000369651.7
5'-nucleotidase ecto
chr4_-_48780242 0.25 ENST00000507711.5
ENST00000358350.9
FRY like transcription coactivator
chr19_-_11346196 0.24 ENST00000586218.5
transmembrane protein 205
chr6_+_143536811 0.24 ENST00000367584.8
phosphatase and actin regulator 2
chr5_+_163437569 0.24 ENST00000512163.5
ENST00000393929.5
ENST00000510097.5
ENST00000340828.7
ENST00000511490.4
ENST00000510664.5
cyclin G1
chr8_-_92017637 0.24 ENST00000422361.6
RUNX1 partner transcriptional co-repressor 1
chr17_+_47209375 0.23 ENST00000572303.1
myosin light chain 4
chr19_-_18086989 0.23 ENST00000430026.7
interleukin 12 receptor subunit beta 1
chr1_-_15976114 0.23 ENST00000375733.6
zinc finger and BTB domain containing 17
chr10_-_70233420 0.22 ENST00000373232.8
ENST00000625364.1
inorganic pyrophosphatase 1
chr2_-_230925226 0.22 ENST00000622008.4
ENST00000392040.5
ENST00000438398.1
ENST00000650999.1
G protein-coupled receptor 55
chr17_+_47209338 0.22 ENST00000393450.5
myosin light chain 4
chr1_+_47333863 0.22 ENST00000471289.2
ENST00000450808.2
cytidine/uridine monophosphate kinase 1
chr3_+_178536205 0.21 ENST00000420517.6
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr13_-_51804094 0.21 ENST00000280056.6
dehydrogenase/reductase 12
chr8_+_78516329 0.21 ENST00000396418.7
ENST00000352966.9
cAMP-dependent protein kinase inhibitor alpha
chr16_-_1420707 0.21 ENST00000442039.3
chromosome 16 open reading frame 91
chr15_+_32030481 0.20 ENST00000454250.7
ENST00000675428.1
ENST00000637552.1
cholinergic receptor nicotinic alpha 7 subunit
chr1_+_47333774 0.20 ENST00000371873.10
cytidine/uridine monophosphate kinase 1
chr19_-_49866848 0.20 ENST00000637897.1
polynucleotide kinase 3'-phosphatase
chr3_-_69013612 0.19 ENST00000295571.9
EGF domain specific O-linked N-acetylglucosamine transferase
chr5_-_160119389 0.19 ENST00000523662.1
ENST00000456329.7
ENST00000307063.9
PWWP domain containing 2A
chr11_-_47565490 0.18 ENST00000525841.5
ENST00000530151.5
ENST00000526419.1
CUGBP Elav-like family member 1
chr10_+_75431605 0.18 ENST00000611255.5
leucine rich melanocyte differentiation associated
chr6_-_83065770 0.18 ENST00000369747.8
ubiquitin protein ligase E3D
chr21_-_33479914 0.17 ENST00000542230.7
transmembrane protein 50B
chr1_-_158426237 0.17 ENST00000641042.1
olfactory receptor family 10 subfamily K member 2
chr18_+_24014390 0.17 ENST00000584250.1
tetratricopeptide repeat domain 39C
chr16_+_788614 0.16 ENST00000262315.14
ENST00000455171.6
ENST00000317063.10
chromosome transmission fidelity factor 18
chr12_+_130953898 0.16 ENST00000261654.10
adhesion G protein-coupled receptor D1
chr11_+_102347312 0.16 ENST00000621637.1
ENST00000613397.4
baculoviral IAP repeat containing 2
chr15_+_32030506 0.16 ENST00000306901.9
ENST00000636440.1
cholinergic receptor nicotinic alpha 7 subunit
chr3_-_132017749 0.16 ENST00000514999.5
copine 4
chr12_-_123233164 0.15 ENST00000537854.5
M-phase phosphoprotein 9
chr5_-_123423337 0.15 ENST00000306467.10
ENST00000675330.1
ENST00000674684.1
centrosomal protein 120
chr16_+_1612337 0.14 ENST00000674071.1
ENST00000397412.8
cramped chromatin regulator homolog 1
chr6_+_116616467 0.13 ENST00000229554.10
ENST00000368581.8
ENST00000368580.4
radial spoke head component 4A
chr14_-_100375602 0.13 ENST00000553395.5
ENST00000553545.5
ENST00000344102.9
ENST00000556338.5
ENST00000553934.1
tryptophanyl-tRNA synthetase 1
chr3_-_69013639 0.13 ENST00000456376.2
ENST00000383701.8
EGF domain specific O-linked N-acetylglucosamine transferase
chr8_+_6708685 0.13 ENST00000518327.1
1-acylglycerol-3-phosphate O-acyltransferase 5
chr3_-_51941874 0.13 ENST00000232888.7
ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
chr7_+_23597373 0.12 ENST00000307471.8
ENST00000409765.5
coiled-coil domain containing 126
chr6_+_85450033 0.12 ENST00000257770.8
ENST00000369646.7
5'-nucleotidase ecto
chr18_+_56651385 0.12 ENST00000615645.4
WD repeat domain 7
chr11_-_72080389 0.12 ENST00000351960.10
ENST00000541719.5
ENST00000535111.5
nuclear mitotic apparatus protein 1
chr2_+_64453969 0.11 ENST00000464281.5
galectin like
chr17_-_41918966 0.10 ENST00000537919.5
ENST00000353196.5
ENST00000393896.6
ATP citrate lyase
chr11_+_71538025 0.10 ENST00000398534.4
keratin associated protein 5-8

Network of associatons between targets according to the STRING database.

First level regulatory network of HESX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
1.2 4.7 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.7 2.1 GO:0098503 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349) DNA 3' dephosphorylation(GO:0098503) DNA 3' dephosphorylation involved in DNA repair(GO:0098504) polynucleotide 3' dephosphorylation(GO:0098506)
0.7 2.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.5 86.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.5 3.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.5 2.0 GO:2000777 endomitotic cell cycle(GO:0007113) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.4 1.7 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.4 1.3 GO:1902214 regulation of interleukin-4-mediated signaling pathway(GO:1902214) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.4 1.1 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.3 1.7 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.3 7.9 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.3 1.7 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.3 4.5 GO:0045059 positive thymic T cell selection(GO:0045059)
0.3 1.6 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.3 0.8 GO:0031247 actin rod assembly(GO:0031247)
0.2 2.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.2 0.9 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.2 2.1 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.2 1.7 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.2 41.7 GO:0002377 immunoglobulin production(GO:0002377)
0.2 1.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 1.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.2 0.6 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.4 GO:0070377 negative regulation of ERK5 cascade(GO:0070377)
0.1 1.2 GO:0044211 CTP salvage(GO:0044211)
0.1 0.9 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.4 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.8 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.9 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.8 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.1 1.7 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 0.9 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 1.4 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.3 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 0.5 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 0.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.3 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.2 GO:0071344 diphosphate metabolic process(GO:0071344)
0.1 0.4 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 4.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.4 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.9 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 2.5 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 0.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.4 GO:0050893 sensory processing(GO:0050893)
0.0 0.6 GO:0009249 protein lipoylation(GO:0009249)
0.0 4.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.4 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.3 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.4 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.6 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.6 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.7 GO:0006089 lactate metabolic process(GO:0006089)
0.0 1.7 GO:0001504 neurotransmitter uptake(GO:0001504)
0.0 1.4 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 1.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 1.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 1.9 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.5 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 1.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 1.3 GO:0048286 lung alveolus development(GO:0048286)
0.0 1.4 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 1.6 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.1 GO:1902846 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.0 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.0 GO:0000964 mitochondrial RNA 5'-end processing(GO:0000964)
0.0 0.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0042022 interleukin-12 receptor complex(GO:0042022)
0.5 2.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.4 4.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 20.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 48.0 GO:0072562 blood microparticle(GO:0072562)
0.2 1.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.9 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.3 GO:0032116 SMC loading complex(GO:0032116)
0.1 0.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.9 GO:0000243 commitment complex(GO:0000243)
0.1 1.1 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.9 GO:0071986 Ragulator complex(GO:0071986)
0.1 1.6 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 1.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.2 GO:0009346 citrate lyase complex(GO:0009346)
0.1 1.1 GO:0032059 bleb(GO:0032059)
0.0 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 3.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.7 GO:0048786 axolemma(GO:0030673) presynaptic active zone(GO:0048786)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 37.9 GO:0005615 extracellular space(GO:0005615)
0.0 3.6 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.0 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0005174 CD40 receptor binding(GO:0005174)
0.7 2.1 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.6 1.7 GO:0016517 interleukin-12 receptor activity(GO:0016517)
0.6 1.7 GO:0017129 triglyceride binding(GO:0017129)
0.5 125.2 GO:0003823 antigen binding(GO:0003823)
0.4 4.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.3 1.3 GO:0097677 STAT family protein binding(GO:0097677)
0.3 2.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 2.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 1.4 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.2 2.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.8 GO:0002060 purine nucleobase binding(GO:0002060)
0.2 1.6 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.2 0.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 1.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.2 0.6 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 1.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 1.6 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 4.7 GO:0043274 phospholipase binding(GO:0043274)
0.1 1.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.5 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 1.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 1.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.8 GO:0046790 virion binding(GO:0046790)
0.1 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.2 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.1 1.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.4 GO:0005534 galactose binding(GO:0005534)
0.0 0.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.9 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 1.7 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 3.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 4.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.9 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0042835 BRE binding(GO:0042835)
0.0 2.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 5.5 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 3.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 8.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 2.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.7 PID IL27 PATHWAY IL27-mediated signaling events
0.0 3.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.9 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 4.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 4.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.3 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 2.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.0 PID P73PATHWAY p73 transcription factor network
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 4.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 4.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 7.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.9 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 1.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 3.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 0.9 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 1.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.8 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.8 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane