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Illumina Body Map 2 (GSE30611)

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Results for HIF1A

Z-value: 0.64

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Transcription factors associated with HIF1A

Gene Symbol Gene ID Gene Info
ENSG00000100644.17 hypoxia inducible factor 1 subunit alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIF1Ahg38_v1_chr14_+_61695777_616958130.173.5e-01Click!

Activity profile of HIF1A motif

Sorted Z-values of HIF1A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_71785167 4.90 ENST00000353065.7
prokineticin 2
chr3_-_71785139 4.46 ENST00000295619.4
prokineticin 2
chr1_-_8879170 2.35 ENST00000489867.2
enolase 1
chr11_+_75768769 2.16 ENST00000228027.12
diacylglycerol O-acyltransferase 2
chr11_+_75768718 2.12 ENST00000376262.7
diacylglycerol O-acyltransferase 2
chr11_+_75768531 2.03 ENST00000604935.5
diacylglycerol O-acyltransferase 2
chr12_+_6868154 1.93 ENST00000462761.5
triosephosphate isomerase 1
chr9_-_120714457 1.74 ENST00000373930.4
multiple EGF like domains 9
chr18_-_3013114 1.56 ENST00000677752.1
lipin 2
chr14_+_92323154 1.52 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
solute carrier family 24 member 4
chr5_+_50666612 1.39 ENST00000281631.10
poly(ADP-ribose) polymerase family member 8
chr1_-_8878646 1.30 ENST00000643438.1
enolase 1
chr6_+_35297809 1.24 ENST00000316637.7
DEF6 guanine nucleotide exchange factor
chr11_+_14643782 1.18 ENST00000282096.9
phosphodiesterase 3B
chr2_-_216081759 1.14 ENST00000265322.8
peroxisomal trans-2-enoyl-CoA reductase
chr19_+_45506579 1.14 ENST00000589627.1
vasodilator stimulated phosphoprotein
chr17_-_37609361 1.13 ENST00000614941.4
ENST00000619541.4
ENST00000622045.4
ENST00000616179.4
ENST00000621136.4
ENST00000612223.5
ENST00000620424.1
synergin gamma
chr1_-_6209389 1.07 ENST00000465335.1
ribosomal protein L22
chr1_+_109619827 1.02 ENST00000667949.2
ENST00000342115.8
ENST00000528667.7
adenosine monophosphate deaminase 2
chr12_-_44876294 1.01 ENST00000429094.7
ENST00000551601.5
ENST00000549027.5
ENST00000452445.6
neural EGFL like 2
chr16_-_88785210 0.97 ENST00000301015.14
piezo type mechanosensitive ion channel component 1
chr11_+_14643826 0.97 ENST00000455098.2
phosphodiesterase 3B
chr22_+_35381086 0.93 ENST00000216117.9
ENST00000677931.1
ENST00000679074.1
heme oxygenase 1
chr15_+_40764055 0.90 ENST00000260447.6
ENST00000561160.1
ENST00000558670.1
ENST00000559445.1
GTP cyclohydrolase I feedback regulator
chr6_-_111873421 0.90 ENST00000368678.8
ENST00000523238.5
ENST00000354650.7
FYN proto-oncogene, Src family tyrosine kinase
chr2_+_46941199 0.89 ENST00000319190.11
ENST00000394850.6
tetratricopeptide repeat domain 7A
chr1_-_159924529 0.89 ENST00000320307.8
transgelin 2
chr5_-_180071708 0.88 ENST00000522208.6
ENST00000521389.6
ring finger protein 130
chr15_+_88638947 0.87 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr12_-_44875647 0.87 ENST00000395487.6
neural EGFL like 2
chr8_-_100722587 0.84 ENST00000523555.6
poly(A) binding protein cytoplasmic 1
chr12_-_44875980 0.81 ENST00000548826.5
neural EGFL like 2
chr8_-_100722731 0.80 ENST00000521865.6
ENST00000520804.2
ENST00000522720.2
ENST00000521067.1
poly(A) binding protein cytoplasmic 1
chr12_-_48924919 0.79 ENST00000444214.6
FKBP prolyl isomerase 11
chr15_+_88639009 0.78 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr6_-_111873272 0.75 ENST00000518295.5
ENST00000484067.6
FYN proto-oncogene, Src family tyrosine kinase
chr15_+_43791842 0.75 ENST00000674451.1
ENST00000630046.2
small EDRK-rich factor 2
chrX_+_78104229 0.75 ENST00000373316.5
phosphoglycerate kinase 1
chr16_-_4416621 0.75 ENST00000570645.5
ENST00000574025.5
ENST00000572898.1
ENST00000537233.6
ENST00000571059.5
coronin 7
chr14_+_64503708 0.74 ENST00000553583.1
zinc finger and BTB domain containing 1
chr2_-_60553618 0.74 ENST00000643716.1
ENST00000359629.10
ENST00000642384.2
ENST00000335712.11
BAF chromatin remodeling complex subunit BCL11A
chr18_+_57435366 0.73 ENST00000491143.3
one cut homeobox 2
chr9_-_133992312 0.71 ENST00000371850.8
vav guanine nucleotide exchange factor 2
chr2_+_111120906 0.69 ENST00000337565.9
ENST00000357757.6
ENST00000308659.12
ENST00000393256.8
ENST00000610735.4
ENST00000615946.4
ENST00000619294.4
ENST00000620862.4
ENST00000621302.4
ENST00000622509.4
ENST00000622612.4
BCL2 like 11
chr5_-_180072086 0.69 ENST00000261947.4
ring finger protein 130
chr7_+_2656092 0.66 ENST00000429448.1
tweety family member 3
chr2_+_27442365 0.66 ENST00000543753.5
ENST00000288873.7
keratinocyte associated protein 3
chr5_-_172771187 0.65 ENST00000239223.4
dual specificity phosphatase 1
chr1_-_1778399 0.64 ENST00000341426.9
NAD kinase
chr9_-_133992281 0.63 ENST00000406606.7
vav guanine nucleotide exchange factor 2
chr7_+_66075913 0.63 ENST00000362000.10
ENST00000395331.4
ENST00000671817.1
argininosuccinate lyase
chr1_+_99969979 0.62 ENST00000427993.7
ENST00000533028.8
ENST00000639221.1
ENST00000638336.1
ENST00000639807.1
ENST00000640715.1
ENST00000465289.6
ENST00000639994.1
ENST00000638988.1
ENST00000640732.1
ENST00000640600.1
ENST00000638338.1
ENST00000638792.1
ENST00000639037.1
solute carrier family 35 member A3
novel protein
chr1_+_28914515 0.61 ENST00000644600.1
ENST00000643173.1
ENST00000648181.1
ENST00000650265.1
ENST00000644780.1
ENST00000343067.9
ENST00000643604.1
ENST00000373797.2
erythrocyte membrane protein band 4.1
chr1_-_1778790 0.61 ENST00000341991.7
NAD kinase
chr1_-_167553799 0.61 ENST00000466652.2
cellular repressor of E1A stimulated genes 1
chr9_+_113221528 0.60 ENST00000374212.5
solute carrier family 31 member 1
chr2_+_191678967 0.60 ENST00000435931.1
nucleic acid binding protein 1
chr2_-_60553558 0.59 ENST00000642439.1
ENST00000356842.9
BAF chromatin remodeling complex subunit BCL11A
chr14_-_92106607 0.59 ENST00000340660.10
ENST00000393287.9
ENST00000429774.6
ENST00000545170.5
ENST00000620536.4
ENST00000621269.4
ataxin 3
chr2_+_112645930 0.59 ENST00000272542.8
solute carrier family 20 member 1
chr2_-_207166818 0.59 ENST00000423015.5
Kruppel like factor 7
chr21_+_44300038 0.58 ENST00000349048.9
ENST00000628044.1
phosphofructokinase, liver type
chr5_+_177426701 0.57 ENST00000507633.5
ENST00000393576.7
ENST00000355958.9
ENST00000528793.5
ENST00000512684.1
G protein-coupled receptor kinase 6
chr3_+_45594167 0.57 ENST00000440097.5
LIM domains containing 1
chr1_+_28914614 0.57 ENST00000645184.1
erythrocyte membrane protein band 4.1
chr7_+_66075811 0.57 ENST00000304874.14
ENST00000673518.1
ENST00000380839.9
argininosuccinate lyase
chr12_+_6868093 0.56 ENST00000488464.6
ENST00000535434.5
ENST00000493987.5
triosephosphate isomerase 1
chr1_-_8878677 0.56 ENST00000234590.10
ENST00000647408.1
enolase 1
chr14_-_95319863 0.55 ENST00000298912.9
calmin
chr12_-_47820562 0.54 ENST00000433685.5
ENST00000447463.5
ENST00000427332.6
histone deacetylase 7
chr8_-_100722174 0.54 ENST00000677380.1
ENST00000677478.1
poly(A) binding protein cytoplasmic 1
chr14_-_87993159 0.54 ENST00000393568.8
ENST00000261304.7
galactosylceramidase
chr16_-_4416564 0.54 ENST00000572467.5
ENST00000251166.9
ENST00000572044.1
ENST00000571052.5
CORO7-PAM16 readthrough
coronin 7
chr14_+_64503943 0.53 ENST00000556965.1
ENST00000554015.5
zinc finger and BTB domain containing 1
chr2_+_241315338 0.53 ENST00000428524.5
ENST00000445030.5
ENST00000407017.5
septin 2
chr1_+_28914597 0.52 ENST00000349460.9
erythrocyte membrane protein band 4.1
chr18_+_46334007 0.52 ENST00000269439.12
ENST00000590330.1
ring finger protein 165
chr8_-_100722036 0.52 ENST00000518196.5
ENST00000519004.5
ENST00000519363.1
ENST00000318607.10
ENST00000520142.2
poly(A) binding protein cytoplasmic 1
chr12_-_121296685 0.52 ENST00000412367.6
ENST00000404169.8
ENST00000402834.8
calcium/calmodulin dependent protein kinase kinase 2
chr5_+_134526176 0.52 ENST00000681820.1
ENST00000512386.6
ENST00000612830.2
jade family PHD finger 2
chr15_-_60592507 0.52 ENST00000449337.6
RAR related orphan receptor A
chr1_-_212699817 0.51 ENST00000243440.2
basic leucine zipper ATF-like transcription factor 3
chr4_-_39527429 0.51 ENST00000501493.6
ENST00000509391.1
ENST00000316423.11
ENST00000507089.5
UDP-glucose 6-dehydrogenase
chr2_+_55232672 0.51 ENST00000404735.1
ENST00000272317.11
ribosomal protein S27a
chr14_-_87992838 0.51 ENST00000544807.6
galactosylceramidase
chr19_+_18419322 0.51 ENST00000348495.10
single stranded DNA binding protein 4
chr11_-_123061173 0.50 ENST00000526110.5
ENST00000227378.7
heat shock protein family A (Hsp70) member 8
chr2_+_216081866 0.50 ENST00000433112.5
ENST00000454545.5
ENST00000295658.8
ENST00000455479.5
ENST00000406027.2
ENST00000437356.7
transmembrane protein 169
chr14_-_92106535 0.49 ENST00000526872.3
ENST00000532032.5
ENST00000506466.5
ENST00000554592.5
ENST00000555381.5
ENST00000553491.5
ENST00000556220.5
ENST00000557311.6
ENST00000617719.4
ENST00000554672.6
ENST00000644486.2
ENST00000502250.5
ENST00000503767.5
ataxin 3
chr14_-_87993143 0.49 ENST00000622264.4
galactosylceramidase
chr8_+_26383102 0.49 ENST00000523949.5
BCL2 interacting protein 3 like
chr7_+_66075876 0.49 ENST00000395332.8
argininosuccinate lyase
chr8_-_144527006 0.48 ENST00000533758.1
ENST00000529415.7
leucine rich repeat containing 24
chr6_-_109381739 0.48 ENST00000504373.2
CD164 molecule
chr16_+_66880503 0.48 ENST00000568869.1
ENST00000311765.4
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr17_+_28725874 0.48 ENST00000579671.5
ENST00000579060.5
NIMA related kinase 8
chr3_+_182793478 0.47 ENST00000493826.1
ENST00000323116.10
ATPase phospholipid transporting 11B (putative)
chr4_+_77158418 0.47 ENST00000509972.1
cyclin G2
chr2_+_231710417 0.47 ENST00000412128.1
prothymosin alpha
chr17_+_67377272 0.47 ENST00000581322.6
ENST00000299954.13
phosphatidylinositol transfer protein cytoplasmic 1
chr1_-_231241090 0.47 ENST00000451322.1
chromosome 1 open reading frame 131
chr2_+_231710460 0.47 ENST00000440384.1
prothymosin alpha
chr20_+_46029206 0.46 ENST00000243964.7
solute carrier family 12 member 5
chr2_+_27442421 0.46 ENST00000407293.5
keratinocyte associated protein 3
chr17_+_27294076 0.45 ENST00000581440.5
ENST00000583742.1
ENST00000579733.5
ENST00000583193.5
ENST00000581185.5
ENST00000427287.6
ENST00000262394.7
ENST00000348811.6
WD repeat and SOCS box containing 1
chr16_+_29455105 0.45 ENST00000567248.1
SLX1 homolog B, structure-specific endonuclease subunit
chr22_-_23838987 0.45 ENST00000318109.12
ENST00000404056.1
ENST00000406855.7
ENST00000476077.1
derlin 3
chr19_+_18419374 0.45 ENST00000270061.12
single stranded DNA binding protein 4
chr9_-_107489754 0.45 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr19_-_48634526 0.44 ENST00000593500.1
ENST00000599385.5
D-box binding PAR bZIP transcription factor
chr5_-_98928992 0.44 ENST00000614616.5
chromodomain helicase DNA binding protein 1
chr4_+_77158356 0.44 ENST00000512918.5
cyclin G2
chr1_-_17439657 0.44 ENST00000375436.9
regulator of chromosome condensation 2
chr10_+_74151202 0.43 ENST00000672429.1
ENST00000539909.6
ENST00000286621.7
adenosine kinase
chr19_+_17511835 0.43 ENST00000595782.1
6-phosphogluconolactonase
chr7_-_92836555 0.43 ENST00000424848.3
cyclin dependent kinase 6
chr12_-_122896066 0.43 ENST00000267202.7
ENST00000535765.5
VPS37B subunit of ESCRT-I
chr8_+_31640358 0.43 ENST00000523534.5
neuregulin 1
chr4_+_152779934 0.42 ENST00000451320.6
ENST00000429148.6
ENST00000353617.7
ENST00000405727.6
ENST00000356064.3
ADP ribosylation factor interacting protein 1
chr10_+_74151232 0.42 ENST00000478611.2
ENST00000673352.1
adenosine kinase
chr14_-_77028663 0.42 ENST00000238647.5
interferon regulatory factor 2 binding protein like
chrX_-_40647509 0.42 ENST00000378421.1
ENST00000378426.5
ENST00000327877.10
chromosome X open reading frame 38
chr6_-_32128191 0.41 ENST00000453203.2
ENST00000375203.8
ENST00000375201.8
activating transcription factor 6 beta
chr15_+_43792305 0.41 ENST00000249786.9
ENST00000409960.6
ENST00000409646.5
ENST00000339624.9
ENST00000409291.5
ENST00000402131.5
ENST00000403425.5
ENST00000430901.1
small EDRK-rich factor 2
chr4_+_77158252 0.40 ENST00000395640.5
cyclin G2
chr1_-_6209244 0.40 ENST00000471204.5
ribosomal protein L22
chr20_+_46029165 0.40 ENST00000616201.4
ENST00000616202.4
ENST00000616933.4
ENST00000626937.2
solute carrier family 12 member 5
chr1_-_231241121 0.40 ENST00000318906.6
ENST00000366649.7
ENST00000366651.7
chromosome 1 open reading frame 131
chr12_+_53954870 0.40 ENST00000243103.4
homeobox C12
chr3_-_52685531 0.40 ENST00000439181.5
ENST00000449505.5
polybromo 1
chr7_+_26291941 0.40 ENST00000412416.5
sorting nexin 10
chr19_+_17511606 0.39 ENST00000252603.7
ENST00000600923.5
6-phosphogluconolactonase
chr19_+_18419425 0.39 ENST00000601357.6
single stranded DNA binding protein 4
chr12_+_112013418 0.38 ENST00000261735.4
ENST00000552052.1
endoplasmic reticulum protein 29
chr11_+_3855629 0.38 ENST00000526596.2
ENST00000300737.8
ENST00000616714.4
stromal interaction molecule 1
chr2_-_88691450 0.38 ENST00000682892.1
eukaryotic translation initiation factor 2 alpha kinase 3
chr7_+_97117718 0.37 ENST00000360382.4
succinate dehydrogenase complex assembly factor 3
chr17_+_67377413 0.37 ENST00000580974.5
phosphatidylinositol transfer protein cytoplasmic 1
chr9_+_78236037 0.36 ENST00000424347.6
ENST00000645398.1
ENST00000643347.1
ENST00000643273.2
ENST00000647199.1
ENST00000643847.1
ENST00000643499.1
ENST00000415759.6
ENST00000376597.9
ENST00000277082.9
ENST00000642669.1
ENST00000642214.1
ENST00000644208.1
ENST00000376598.3
centrosomal protein 78
chr2_+_206159580 0.36 ENST00000236957.9
ENST00000392221.5
ENST00000445505.5
eukaryotic translation elongation factor 1 beta 2
chr1_-_6199553 0.36 ENST00000465387.5
ENST00000234875.9
ribosomal protein L22
chr16_-_69132557 0.36 ENST00000523421.5
ENST00000522091.1
ENST00000448552.7
chromosome transmission fidelity factor 8
chr1_-_219928551 0.36 ENST00000366926.4
solute carrier family 30 member 10
chr20_+_46029009 0.36 ENST00000608944.5
solute carrier family 12 member 5
chr13_-_30464234 0.35 ENST00000399489.5
ENST00000339872.8
high mobility group box 1
chr12_-_51814925 0.35 ENST00000642069.2
transmembrane and death domain 1
chr12_-_47819866 0.35 ENST00000354334.7
ENST00000430670.5
ENST00000552960.5
ENST00000440293.5
ENST00000080059.12
histone deacetylase 7
chr17_+_75109939 0.35 ENST00000581078.1
ENST00000245543.6
ENST00000582136.5
armadillo repeat containing 7
chr6_+_108166015 0.34 ENST00000368986.9
nuclear receptor subfamily 2 group E member 1
chrX_+_16786421 0.34 ENST00000398155.4
ENST00000380122.10
taxilin gamma
chr12_+_112013348 0.34 ENST00000455836.1
endoplasmic reticulum protein 29
chr10_-_5977589 0.34 ENST00000620345.4
ENST00000397251.7
ENST00000397248.6
ENST00000622442.4
ENST00000620865.4
interleukin 15 receptor subunit alpha
chrX_+_24465223 0.33 ENST00000379162.9
ENST00000568479.2
pyruvate dehydrogenase kinase 3
chr7_+_97117676 0.33 ENST00000432641.3
succinate dehydrogenase complex assembly factor 3
chr9_-_120877026 0.33 ENST00000436309.5
PHD finger protein 19
chr2_-_197499857 0.33 ENST00000428204.6
ENST00000678170.1
ENST00000676933.1
ENST00000678621.1
heat shock protein family D (Hsp60) member 1
chr17_+_75110021 0.32 ENST00000584947.1
armadillo repeat containing 7
chr1_-_8878706 0.32 ENST00000646156.1
enolase 1
chr8_-_143597094 0.32 ENST00000531953.5
ENST00000526133.1
eukaryotic translation elongation factor 1 delta
chr2_+_30147516 0.32 ENST00000402708.5
yippee like 5
chr7_+_44044634 0.32 ENST00000490734.6
drebrin like
chr9_-_137028223 0.32 ENST00000341511.11
ATP binding cassette subfamily A member 2
chr7_-_5529949 0.31 ENST00000642480.2
ENST00000417101.2
actin beta
chr11_+_73787927 0.31 ENST00000537007.5
mitochondrial ribosomal protein L48
chr3_+_19947316 0.31 ENST00000422242.1
RAB5A, member RAS oncogene family
chr14_-_64503775 0.31 ENST00000608382.6
zinc finger and BTB domain containing 25
chrX_+_630789 0.31 ENST00000381575.6
short stature homeobox
chr9_+_114611206 0.31 ENST00000374049.4
ENST00000288502.9
transmembrane protein 268
chr10_-_100185993 0.30 ENST00000421367.7
ENST00000370408.2
ENST00000407654.7
ER lipid raft associated 1
chr1_-_33431079 0.30 ENST00000683057.1
polyhomeotic homolog 2
chr11_-_62646598 0.30 ENST00000648273.1
ENST00000356638.8
ENST00000346178.8
ENST00000534779.5
ENST00000525994.1
ENST00000540933.5
glucosidase II alpha subunit
chr7_-_127392060 0.29 ENST00000436992.5
zinc finger protein 800
chr11_+_67023085 0.29 ENST00000527043.6
synaptotagmin 12
chr1_+_99970430 0.29 ENST00000370153.6
solute carrier family 35 member A3
chr16_+_53131043 0.29 ENST00000563410.1
chromodomain helicase DNA binding protein 9
chr4_+_151099637 0.29 ENST00000512690.5
ENST00000508783.5
ENST00000512797.5
ENST00000507327.5
ENST00000515792.5
ENST00000506126.5
ribosomal protein S3A
chr2_+_202634960 0.28 ENST00000392238.3
family with sequence similarity 117 member B
chr11_+_18698768 0.28 ENST00000280734.3
transmembrane protein 86A
chr19_-_1592306 0.28 ENST00000585967.5
ENST00000592965.2
methyl-CpG binding domain protein 3
chr18_-_76495191 0.28 ENST00000443185.7
zinc finger protein 516
chr1_+_12063357 0.28 ENST00000417814.3
TNF receptor superfamily member 8
chr2_+_206159884 0.28 ENST00000392222.7
eukaryotic translation elongation factor 1 beta 2
chr4_-_39527558 0.28 ENST00000515021.5
ENST00000510490.1
UDP-glucose 6-dehydrogenase
chr10_-_5977492 0.28 ENST00000530685.5
ENST00000397255.7
ENST00000379971.5
ENST00000528354.5
ENST00000397250.6
ENST00000429135.2
interleukin 15 receptor subunit alpha
chr1_-_167553745 0.27 ENST00000370509.5
cellular repressor of E1A stimulated genes 1
chr11_+_73787853 0.27 ENST00000310614.12
ENST00000497094.6
ENST00000411840.6
ENST00000535277.5
ENST00000398483.7
ENST00000542303.5
mitochondrial ribosomal protein L48
chr22_-_19431692 0.27 ENST00000340170.8
ENST00000263208.5
histone cell cycle regulator
chr12_+_106955828 0.27 ENST00000547242.5
ENST00000551489.5
ENST00000550344.5
transmembrane protein 263
chr10_+_70815889 0.27 ENST00000373202.8
sphingosine-1-phosphate lyase 1
chr3_+_19947238 0.27 ENST00000443878.1
RAB5A, member RAS oncogene family
chr9_-_137028271 0.27 ENST00000265662.9
ENST00000371605.7
ATP binding cassette subfamily A member 2
chr10_+_119207560 0.27 ENST00000392870.3
G protein-coupled receptor kinase 5
chr17_-_18039158 0.27 ENST00000585101.5
ENST00000474627.8
ENST00000444058.1
ATP synthase mitochondrial F1 complex assembly factor 2
chrX_-_149540900 0.27 ENST00000608355.1
ENST00000651111.1
long intergenic non-protein coding RNA 893
novel protein
chr16_-_18801424 0.26 ENST00000546206.6
ENST00000562819.5
ENST00000304414.12
ENST00000562234.2
ENST00000567078.2
ADP ribosylation factor like GTPase 6 interacting protein 1
novel protein
chr5_+_71587351 0.26 ENST00000683339.1
methylcrotonoyl-CoA carboxylase 2
chr6_+_151452447 0.26 ENST00000367294.4
acidic residue methyltransferase 1
chr9_-_137114678 0.26 ENST00000497375.1
ENST00000371579.7
dipeptidyl peptidase 7
chr3_-_50337438 0.26 ENST00000327761.7
Ras association domain family member 1
chr3_+_19947074 0.26 ENST00000273047.9
RAB5A, member RAS oncogene family

Network of associatons between targets according to the STRING database.

First level regulatory network of HIF1A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.3 GO:0071400 cellular response to oleic acid(GO:0071400)
0.5 1.5 GO:0006683 galactosylceramide catabolic process(GO:0006683)
0.5 2.5 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.4 1.7 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.4 1.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.4 4.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.3 1.2 GO:0040040 thermosensory behavior(GO:0040040)
0.3 1.1 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.3 1.3 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.2 1.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 0.7 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.2 0.9 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.2 1.3 GO:1904799 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.2 0.8 GO:0006169 adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175)
0.2 0.9 GO:0032764 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.2 0.7 GO:0043335 protein unfolding(GO:0043335)
0.2 2.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.2 2.5 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 0.7 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.2 0.5 GO:0045556 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.2 9.4 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.2 1.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 0.6 GO:0051230 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1 0.4 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 2.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.8 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.5 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.7 GO:0002840 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.1 0.4 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 1.6 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.3 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.5 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 1.1 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.4 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.1 1.0 GO:0032264 IMP salvage(GO:0032264)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.8 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.5 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.6 GO:0072719 cellular response to cisplatin(GO:0072719)
0.1 0.6 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.8 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.2 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 0.8 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.2 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.5 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 0.3 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 0.7 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 1.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.2 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 1.7 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.2 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.9 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.4 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 1.9 GO:0097186 amelogenesis(GO:0097186)
0.1 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 1.1 GO:0035330 regulation of hippo signaling(GO:0035330)
0.1 1.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.8 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:0060876 semicircular canal formation(GO:0060876)
0.0 0.3 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.3 GO:0045007 depurination(GO:0045007)
0.0 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.2 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.2 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.0 0.3 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.2 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.1 GO:0070077 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079)
0.0 0.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.6 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.7 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.6 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.2 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.5 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.4 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.2 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.4 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.0 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.3 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0009093 cysteine biosynthetic process from serine(GO:0006535) cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 1.2 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.2 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.5 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.3 GO:0001553 luteinization(GO:0001553)
0.0 0.4 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.9 GO:0042133 neurotransmitter metabolic process(GO:0042133)
0.0 2.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.4 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.9 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.1 GO:0009107 lipoate metabolic process(GO:0009106) lipoate biosynthetic process(GO:0009107)
0.0 0.2 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.0 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0044030 regulation of DNA methylation(GO:0044030)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.5 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 0.8 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 0.6 GO:0070876 SOSS complex(GO:0070876)
0.1 1.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 2.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.8 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.5 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 2.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 6.2 GO:0005811 lipid particle(GO:0005811)
0.0 1.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 2.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 0.6 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.0 1.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.3 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.8 2.5 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.7 2.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.6 1.7 GO:0004056 argininosuccinate lyase activity(GO:0004056)
0.6 1.7 GO:0008859 exoribonuclease II activity(GO:0008859)
0.5 1.5 GO:0004336 galactosylceramidase activity(GO:0004336)
0.4 1.1 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.4 4.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.7 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.2 0.9 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.2 1.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.8 GO:0004001 adenosine kinase activity(GO:0004001)
0.2 1.6 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 0.8 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.2 0.9 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.8 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.4 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.3 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 1.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.8 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.4 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 1.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.0 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 2.0 GO:0008494 translation activator activity(GO:0008494)
0.1 0.6 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 1.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.3 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 1.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 2.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.4 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.2 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.0 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.4 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0033746 histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 1.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.0 1.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0070025 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.0 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 1.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 9.9 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 1.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.7 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 7.9 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 1.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.9 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 2.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 3.2 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 3.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 1.1 REACTOME TRANSLATION Genes involved in Translation
0.0 0.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines