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Illumina Body Map 2 (GSE30611)

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Results for HMBOX1

Z-value: 0.79

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Transcription factors associated with HMBOX1

Gene Symbol Gene ID Gene Info
ENSG00000147421.18 homeobox containing 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMBOX1hg38_v1_chr8_+_28890365_288904210.125.2e-01Click!

Activity profile of HMBOX1 motif

Sorted Z-values of HMBOX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_43558968 2.57 ENST00000647834.1
ENST00000373100.7
ENST00000648083.1
ENST00000648530.1
serum/glucocorticoid regulated kinase 2
chr9_-_92536031 2.32 ENST00000344604.9
ENST00000375540.5
extracellular matrix protein 2
chr9_-_92536067 1.95 ENST00000444490.6
extracellular matrix protein 2
chr8_+_30387064 1.58 ENST00000523115.5
ENST00000519647.5
RNA binding protein, mRNA processing factor
chr6_+_112087576 1.47 ENST00000368656.7
ENST00000604268.1
family with sequence similarity 229 member B
chr1_-_109740304 1.44 ENST00000540225.2
glutathione S-transferase mu 3
chrX_-_10833643 1.39 ENST00000380785.5
ENST00000380787.5
midline 1
chr8_-_38468601 1.32 ENST00000341462.9
ENST00000683765.1
ENST00000356207.9
ENST00000326324.10
ENST00000335922.9
ENST00000532791.5
fibroblast growth factor receptor 1
chr8_-_38468627 1.31 ENST00000683815.1
ENST00000684654.1
ENST00000447712.7
ENST00000397091.9
fibroblast growth factor receptor 1
chr12_-_52519117 1.27 ENST00000551188.5
keratin 5
chr4_-_151227881 1.24 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr6_+_87407965 1.24 ENST00000369562.9
cilia and flagella associated protein 206
chr10_-_5003850 1.22 ENST00000421196.7
ENST00000455190.2
ENST00000380753.8
aldo-keto reductase family 1 member C2
chr7_-_120858303 1.21 ENST00000415871.5
ENST00000430985.1
tetraspanin 12
chr13_+_23570370 1.07 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr3_-_149377637 1.06 ENST00000305366.8
transmembrane 4 L six family member 1
chr12_+_53098846 0.95 ENST00000650247.1
ENST00000549628.1
insulin like growth factor binding protein 6
chr4_-_109801978 0.93 ENST00000510800.1
ENST00000512148.5
ENST00000394634.7
ENST00000394635.8
ENST00000645635.1
complement factor I
novel protein
chr8_-_123737378 0.93 ENST00000419625.6
ENST00000262219.10
annexin A13
chr12_-_25195074 0.93 ENST00000354189.9
ENST00000676236.1
ENST00000545133.5
ENST00000554347.1
ENST00000674567.1
ENST00000395987.8
ENST00000320267.13
ENST00000395990.6
cilia and flagella associated protein 94
chr7_+_134891400 0.90 ENST00000393118.6
caldesmon 1
chr11_+_34622053 0.88 ENST00000530286.5
ENST00000533754.5
ETS homologous factor
chr20_-_56005466 0.88 ENST00000064571.3
cerebellin 4 precursor
chr7_+_134891566 0.85 ENST00000424922.5
ENST00000495522.1
caldesmon 1
chrX_-_116462965 0.85 ENST00000371894.5
cancer/testis antigen 83
chr3_-_64268161 0.84 ENST00000564377.6
prickle planar cell polarity protein 2
chr1_-_169427428 0.80 ENST00000456107.1
ENST00000367805.7
ENST00000491570.2
coiled-coil domain containing 181
chrX_-_15664798 0.77 ENST00000380342.4
collectrin, amino acid transport regulator
chr2_+_36696790 0.74 ENST00000497382.5
ENST00000404084.5
ENST00000379241.7
ENST00000401530.5
vitrin
chr14_+_75069632 0.73 ENST00000439583.2
ENST00000554763.2
ENST00000524913.3
ENST00000525046.2
ENST00000674086.1
ENST00000526130.2
ENST00000674094.1
ENST00000532198.2
zinc finger C2HC-type containing 1C
chr7_+_128455849 0.72 ENST00000435296.2
ENST00000257696.5
hypoxia inducible lipid droplet associated
chr17_+_43025203 0.71 ENST00000587250.4
Rho family GTPase 2
chr1_-_110391041 0.71 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
solute carrier family 16 member 4
chr19_-_35501878 0.71 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
dermokine
chr18_-_36798482 0.70 ENST00000590258.2
tubulin polyglutamylase complex subunit 2
chr4_-_139084289 0.70 ENST00000510408.5
ENST00000379549.7
ENST00000358635.7
E74 like ETS transcription factor 2
chr6_-_112087451 0.69 ENST00000368662.10
tubulin epsilon 1
chr12_-_55842950 0.68 ENST00000548629.5
matrix metallopeptidase 19
chr20_+_43559060 0.68 ENST00000485914.2
serum/glucocorticoid regulated kinase 2
chr2_+_181985846 0.66 ENST00000682840.1
ENST00000409137.7
ENST00000280295.7
protein phosphatase 1 regulatory inhibitor subunit 1C
chr1_-_150697128 0.66 ENST00000427665.1
ENST00000271732.8
golgi phosphoprotein 3 like
chr3_+_52410635 0.66 ENST00000327906.8
PHD finger protein 7
chr8_-_28490220 0.66 ENST00000517673.5
ENST00000380254.7
ENST00000518734.5
ENST00000346498.6
F-box protein 16
chr6_-_136550819 0.65 ENST00000616617.4
ENST00000618822.4
microtubule associated protein 7
chr19_+_56507800 0.63 ENST00000591537.5
ENST00000308031.10
zinc finger protein 471
chr2_+_36696758 0.62 ENST00000457137.6
vitrin
chr17_-_1492660 0.62 ENST00000648651.1
myosin IC
chr15_+_79311084 0.61 ENST00000299705.10
transmembrane p24 trafficking protein 3
chr4_-_158159657 0.61 ENST00000590648.5
golgi associated kinase 1B
chr17_-_10549612 0.61 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
myosin heavy chain 2
chr5_-_78549151 0.61 ENST00000515007.6
LHFPL tetraspan subfamily member 2
chr14_+_104865256 0.58 ENST00000414716.8
ENST00000556508.5
ENST00000453495.2
centrosomal protein 170B
chr1_+_103561757 0.58 ENST00000435302.5
amylase alpha 2B
chrX_-_42778155 0.57 ENST00000378131.4
PPP1R2C family member C
chrX_-_21758097 0.55 ENST00000379494.4
small muscle protein X-linked
chr17_-_10549652 0.55 ENST00000245503.10
myosin heavy chain 2
chrX_-_100732100 0.55 ENST00000372981.1
ENST00000263033.9
synaptotagmin like 4
chr1_+_151721508 0.55 ENST00000479191.2
regulatory subunit of type II PKA R-subunit domain containing 1
chr1_+_40247926 0.55 ENST00000372766.4
transmembrane and coiled-coil domains 2
chr9_+_69123009 0.55 ENST00000647986.1
tight junction protein 2
chr1_+_173635332 0.54 ENST00000417563.3
testis expressed 50
chr12_-_32896757 0.53 ENST00000070846.11
ENST00000340811.9
plakophilin 2
chr9_+_125748175 0.51 ENST00000491787.7
ENST00000447726.6
PBX homeobox 3
chr3_-_93973933 0.51 ENST00000650591.1
protein S
chr4_-_185956348 0.51 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
sorbin and SH3 domain containing 2
chr12_-_4649043 0.51 ENST00000545990.6
ENST00000228850.6
A-kinase anchoring protein 3
chr14_+_44962177 0.49 ENST00000361462.7
ENST00000361577.7
TOG array regulator of axonemal microtubules 1
chr17_-_28576882 0.48 ENST00000395319.7
ENST00000581807.5
ENST00000226253.9
ENST00000584086.5
ENST00000395321.6
aldolase, fructose-bisphosphate C
chr19_+_49581304 0.47 ENST00000246794.10
proline rich and Gla domain 2
chr16_-_30585497 0.47 ENST00000567773.1
ENST00000395216.3
ENST00000470110.2
zinc finger protein 785
chr2_-_132671487 0.47 ENST00000345008.6
LY6/PLAUR domain containing 1
chr3_-_121749704 0.47 ENST00000393667.7
ENST00000340645.9
ENST00000614479.4
golgin B1
chr1_-_169427408 0.46 ENST00000367806.7
coiled-coil domain containing 181
chr10_+_35195843 0.45 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr8_+_93698561 0.45 ENST00000523475.5
CBY1 interacting BAR domain containing 1
chr20_-_37158904 0.45 ENST00000417458.5
maestro heat like repeat family member 8
chr14_-_23286082 0.44 ENST00000357460.7
homeobox and leucine zipper encoding
chr2_-_219245465 0.44 ENST00000392089.6
galactosidase beta 1 like
chr13_+_76992412 0.44 ENST00000636705.1
CLN5 intracellular trafficking protein
chr5_-_157652432 0.44 ENST00000265007.11
SRY-box transcription factor 30
chr17_-_3668557 0.43 ENST00000225525.4
Tax1 binding protein 3
chrX_+_22272913 0.43 ENST00000323684.4
Cbl proto-oncogene like 2
chr5_+_93583212 0.43 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chrX_+_103628959 0.43 ENST00000372625.8
ENST00000372624.3
transcription elongation factor A like 1
chr7_-_16465728 0.42 ENST00000307068.5
sclerostin domain containing 1
chr8_-_115492221 0.42 ENST00000518018.1
transcriptional repressor GATA binding 1
chr5_+_126465144 0.40 ENST00000511134.1
GRAM domain containing 2B
chr1_-_9910169 0.40 ENST00000377263.6
catenin beta interacting protein 1
chr1_+_175067831 0.40 ENST00000239462.9
tenascin N
chr14_+_75069577 0.40 ENST00000238686.8
zinc finger C2HC-type containing 1C
chr7_-_111562455 0.40 ENST00000452895.5
ENST00000405709.7
ENST00000452753.1
ENST00000331762.7
inner mitochondrial membrane peptidase subunit 2
chr1_-_201377652 0.39 ENST00000455702.6
ENST00000367320.6
ENST00000421663.6
ENST00000412633.3
ENST00000367318.10
ENST00000422165.6
ENST00000656932.1
ENST00000438742.6
ENST00000367322.6
ENST00000458432.6
ENST00000509001.5
ENST00000660295.1
troponin T2, cardiac type
chr10_+_87659839 0.38 ENST00000456849.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr10_-_24622817 0.38 ENST00000636789.1
Rho GTPase activating protein 21
chr14_+_50533026 0.37 ENST00000441560.6
atlastin GTPase 1
chr2_-_61854013 0.37 ENST00000404929.6
FAM161 centrosomal protein A
chr6_+_26087417 0.37 ENST00000357618.10
ENST00000309234.10
homeostatic iron regulator
chr12_-_88029385 0.37 ENST00000298699.7
ENST00000550553.5
chromosome 12 open reading frame 50
chr5_-_157652364 0.36 ENST00000311371.9
SRY-box transcription factor 30
chr5_-_16916400 0.36 ENST00000513882.5
myosin X
chr9_+_73151833 0.35 ENST00000456643.5
ENST00000257497.11
ENST00000415424.5
annexin A1
chr11_+_1839602 0.35 ENST00000617947.4
ENST00000252898.11
troponin I2, fast skeletal type
chr17_+_44847874 0.35 ENST00000253410.3
HIG1 hypoxia inducible domain family member 1B
chr14_-_23154369 0.35 ENST00000453702.5
solute carrier family 7 member 8
chr1_-_25859352 0.35 ENST00000374298.4
ENST00000538789.5
aurora kinase A and ninein interacting protein
chr2_-_61854119 0.35 ENST00000405894.3
FAM161 centrosomal protein A
chr10_-_87841336 0.35 ENST00000495903.1
ATPase family AAA domain containing 1
chr19_+_6740878 0.34 ENST00000596673.1
thyroid hormone receptor interactor 10
chr6_+_28267355 0.34 ENST00000614088.1
ENST00000619937.4
zinc finger and SCAN domain containing 26
chr2_-_219245389 0.34 ENST00000428427.1
ENST00000432839.1
ENST00000295759.12
ENST00000424620.1
galactosidase beta 1 like
chr1_+_236394268 0.34 ENST00000334232.9
EDAR associated death domain
chr14_-_50532518 0.34 ENST00000682126.1
mitogen-activated protein kinase kinase kinase kinase 5
chr2_-_177314907 0.33 ENST00000443132.1
ENST00000625449.2
ENST00000586532.5
novel transcript
nuclear factor, erythroid 2 like 2
chrX_+_71283577 0.33 ENST00000420903.6
ENST00000373856.8
ENST00000678437.1
ENST00000678830.1
ENST00000677879.1
ENST00000373841.5
ENST00000276079.13
ENST00000676797.1
ENST00000678660.1
ENST00000678231.1
ENST00000677612.1
ENST00000413858.5
ENST00000450092.6
non-POU domain containing octamer binding
chrX_-_10620534 0.32 ENST00000317552.9
midline 1
chr20_+_87665 0.31 ENST00000382410.3
defensin beta 125
chr11_+_57763820 0.31 ENST00000674106.1
catenin delta 1
chr19_-_7489003 0.31 ENST00000221480.6
peroxisomal biogenesis factor 11 gamma
chr3_-_57544324 0.31 ENST00000495027.5
ENST00000351747.6
ENST00000389536.8
ENST00000311202.7
dynein axonemal heavy chain 12
chr17_-_3668640 0.31 ENST00000611779.4
Tax1 binding protein 3
chr6_-_31972290 0.31 ENST00000375349.7
decapping exoribonuclease
chr14_-_23154422 0.30 ENST00000422941.6
solute carrier family 7 member 8
chr10_+_59177161 0.30 ENST00000373878.3
phytanoyl-CoA 2-hydroxylase interacting protein like
chr14_-_50532590 0.30 ENST00000013125.9
mitogen-activated protein kinase kinase kinase kinase 5
chr1_+_64203610 0.29 ENST00000371077.10
ENST00000611228.4
ubiquitin conjugating enzyme E2 U
chr6_-_131701401 0.29 ENST00000315453.4
olfactory receptor family 2 subfamily A member 4
chr7_-_120857124 0.28 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr7_-_47539240 0.27 ENST00000450444.5
tensin 3
chrX_+_108582484 0.27 ENST00000483338.1
collagen type IV alpha 5 chain
chr1_-_150010675 0.27 ENST00000417191.2
ENST00000581312.6
OTU deubiquitinase 7B
chr14_-_89954518 0.27 ENST00000556005.1
ENST00000555872.5
EF-hand calcium binding domain 11
chr8_-_94436926 0.27 ENST00000481490.3
fibrinogen silencer binding protein
chr3_+_57060658 0.27 ENST00000334325.2
spermatogenesis associated 12
chr6_-_31972123 0.27 ENST00000337523.10
decapping exoribonuclease
chr6_+_122717544 0.26 ENST00000354275.2
ENST00000368446.1
cAMP-dependent protein kinase inhibitor beta
chr2_+_108719473 0.26 ENST00000283195.11
RAN binding protein 2
chr2_+_233778330 0.26 ENST00000389758.3
maestro heat like repeat family member 2A
chr17_+_28473635 0.26 ENST00000314669.10
ENST00000545060.2
solute carrier family 13 member 2
chr10_-_32935511 0.25 ENST00000423113.5
integrin subunit beta 1
chr7_+_101085464 0.25 ENST00000306085.11
ENST00000412507.1
tripartite motif containing 56
chr7_-_47539591 0.25 ENST00000442536.6
ENST00000458317.6
tensin 3
chr14_+_67240713 0.25 ENST00000677382.1
membrane palmitoylated protein 5
chr12_+_93677556 0.25 ENST00000542893.2
CASP2 and RIPK1 domain containing adaptor with death domain
chr1_-_9910310 0.24 ENST00000400904.7
catenin beta interacting protein 1
chr19_+_16067526 0.24 ENST00000646974.2
tropomyosin 4
chr1_+_153968237 0.24 ENST00000368601.5
ENST00000368603.5
ENST00000368600.7
cAMP responsive element binding protein 3 like 4
chrX_+_71283186 0.24 ENST00000535149.5
non-POU domain containing octamer binding
chr1_-_23177683 0.24 ENST00000302291.8
leucine zipper protein 1
chr14_-_55191534 0.24 ENST00000395425.6
ENST00000247191.7
DLG associated protein 5
chr18_-_35290184 0.24 ENST00000589178.5
ENST00000592278.1
ENST00000333206.10
ENST00000592211.1
ENST00000420878.7
ENST00000610712.1
ENST00000586922.2
zinc finger and SCAN domain containing 30
novel transcript
chr17_-_58417521 0.24 ENST00000584437.5
ENST00000407977.7
ring finger protein 43
chr6_+_110982028 0.24 ENST00000441448.7
ribosome production factor 2 homolog
chr11_-_125111579 0.23 ENST00000532156.5
ENST00000532407.5
ENST00000279968.8
ENST00000527766.5
ENST00000529583.5
ENST00000524373.5
ENST00000527271.5
ENST00000526175.5
ENST00000529609.5
ENST00000682305.1
ENST00000533273.1
transmembrane protein 218
chr17_+_28473278 0.23 ENST00000444914.7
solute carrier family 13 member 2
chr5_+_132369691 0.22 ENST00000245407.8
solute carrier family 22 member 5
chrX_+_110003095 0.22 ENST00000372073.5
ENST00000372068.7
ENST00000288381.4
transmembrane protein 164
chr10_-_50279715 0.22 ENST00000395526.9
N-acylsphingosine amidohydrolase 2
chr12_-_10998304 0.22 ENST00000538986.2
taste 2 receptor member 20
chr12_-_11022620 0.22 ENST00000390673.2
taste 2 receptor member 19
chr3_-_121749645 0.22 ENST00000494517.5
golgin B1
chr6_-_73354255 0.21 ENST00000370370.4
developmental pluripotency associated 5
chr3_+_88338451 0.20 ENST00000637986.2
casein kinase 2 subunit alpha' interacting protein
chr17_-_10549694 0.20 ENST00000622564.4
myosin heavy chain 2
chr1_+_151070740 0.20 ENST00000368918.8
GA binding protein transcription factor subunit beta 2
chr10_+_24466487 0.19 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr3_+_38305936 0.19 ENST00000273173.4
solute carrier family 22 member 14
chr7_+_128739292 0.19 ENST00000535011.6
ENST00000542996.6
ENST00000249364.9
ENST00000449187.6
calumenin
chr1_-_204685700 0.19 ENST00000367177.4
leucine rich repeat neuronal 2
chr15_+_75347030 0.18 ENST00000566313.5
ENST00000355059.9
ENST00000568059.1
ENST00000568881.1
nei like DNA glycosylase 1
chr7_+_130344810 0.18 ENST00000497503.5
ENST00000463587.5
ENST00000461828.5
ENST00000474905.6
ENST00000494311.1
ENST00000466363.6
carboxypeptidase A5
chr14_+_34993240 0.18 ENST00000677647.1
signal recognition particle 54
chr6_+_31971831 0.18 ENST00000375331.7
ENST00000375333.3
serine/threonine kinase 19
chr3_+_113211003 0.18 ENST00000464546.5
BOC cell adhesion associated, oncogene regulated
chr15_-_60391127 0.18 ENST00000559350.5
ENST00000558986.5
ENST00000560389.5
annexin A2
chrX_+_1591590 0.18 ENST00000313871.9
ENST00000381261.8
A-kinase anchoring protein 17A
chr16_+_21678514 0.17 ENST00000286149.8
ENST00000388958.8
otoancorin
chr1_-_27155118 0.17 ENST00000263980.8
solute carrier family 9 member A1
chr8_+_66043413 0.17 ENST00000522619.1
DnaJ heat shock protein family (Hsp40) member C5 beta
chr5_-_138331770 0.17 ENST00000415130.6
ENST00000323760.11
ENST00000503022.5
cell division cycle 25C
chr4_+_25914275 0.17 ENST00000514384.1
small integral membrane protein 20
chr7_+_17299234 0.17 ENST00000637807.1
novel protein
chr19_-_56314788 0.17 ENST00000592509.5
ENST00000592679.5
ENST00000683990.1
ENST00000588442.5
ENST00000593106.5
ENST00000587492.5
zinc finger and SCAN domain containing 5A
chr2_+_46542474 0.17 ENST00000238738.9
ras homolog family member Q
chr6_+_28267107 0.16 ENST00000621053.1
ENST00000617168.4
ENST00000421553.7
ENST00000611552.2
ENST00000623276.3
novel protein
zinc finger and SCAN domain containing 26
chr6_+_28267044 0.16 ENST00000316606.10
zinc finger and SCAN domain containing 26
chr19_-_11505799 0.16 ENST00000293771.10
zinc finger protein 653
chr1_+_116111395 0.16 ENST00000684484.1
ENST00000369500.4
mab-21 like 3
chr5_+_141382702 0.15 ENST00000617050.1
ENST00000518325.2
protocadherin gamma subfamily A, 7
chr17_-_47851155 0.15 ENST00000536300.2
Sp6 transcription factor
chr10_+_113553039 0.15 ENST00000351270.4
hyaluronan binding protein 2
chr4_-_47463649 0.15 ENST00000381571.6
COMM domain containing 8
chr12_-_56333893 0.15 ENST00000547572.1
ENST00000257931.9
ENST00000610546.4
ENST00000440411.7
poly(A) specific ribonuclease subunit PAN2
chr3_+_36993798 0.14 ENST00000455445.6
ENST00000539477.6
ENST00000435176.5
ENST00000429117.5
ENST00000441265.6
mutL homolog 1
chr6_-_117425855 0.14 ENST00000368508.7
ROS proto-oncogene 1, receptor tyrosine kinase
chr14_-_70416994 0.14 ENST00000621525.4
ENST00000256366.6
SYNJ2BP-COX16 readthrough
synaptojanin 2 binding protein
chr9_-_99221897 0.13 ENST00000476832.2
ALG2 alpha-1,3/1,6-mannosyltransferase
chr22_-_36776147 0.13 ENST00000340630.9
intraflagellar transport 27
chr9_-_23779369 0.13 ENST00000440102.1
ELAV like RNA binding protein 2
chr17_+_75459707 0.13 ENST00000581519.5
transmembrane protein 94
chr22_-_36776067 0.13 ENST00000417951.6
ENST00000433985.7
ENST00000430701.5
intraflagellar transport 27

Network of associatons between targets according to the STRING database.

First level regulatory network of HMBOX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.5 1.4 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.2 0.7 GO:0035425 autocrine signaling(GO:0035425)
0.2 1.2 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.4 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.6 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.4 GO:0034758 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.4 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.5 GO:0048496 adherens junction maintenance(GO:0034334) maintenance of organ identity(GO:0048496)
0.1 1.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.4 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.4 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.2 GO:0021503 neural fold bending(GO:0021503)
0.1 0.2 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.1 1.4 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 1.6 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.7 GO:0001554 luteolysis(GO:0001554)
0.1 0.2 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.1 0.6 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.7 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.0 0.3 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.4 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.5 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.2 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0052417 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.3 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.0 0.1 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 1.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.4 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.3 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 1.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.6 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.7 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.0 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.5 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 1.8 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.8 GO:0015695 organic cation transport(GO:0015695)
0.0 5.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 2.9 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.7 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.6 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.7 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0001534 radial spoke(GO:0001534)
0.2 1.3 GO:0002177 manchette(GO:0002177)
0.2 5.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.6 GO:0045160 myosin I complex(GO:0045160)
0.1 1.7 GO:0030478 actin cap(GO:0030478)
0.1 1.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.6 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.1 1.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.3 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.3 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.6 GO:0042382 paraspeckles(GO:0042382)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 1.6 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.7 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.3 GO:0070052 collagen V binding(GO:0070052)
0.3 1.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.2 1.2 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.2 2.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.6 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.5 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 3.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 1.4 GO:0043295 glutathione binding(GO:0043295)
0.1 2.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.8 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.7 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 1.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.4 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.4 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 2.0 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 6.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction