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Illumina Body Map 2 (GSE30611)

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Results for HMX1

Z-value: 1.68

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Transcription factors associated with HMX1

Gene Symbol Gene ID Gene Info
ENSG00000215612.8 H6 family homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMX1hg38_v1_chr4_-_8871817_88718570.067.3e-01Click!

Activity profile of HMX1 motif

Sorted Z-values of HMX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_50304693 7.19 ENST00000331340.8
ENST00000413698.5
ENST00000612658.4
ENST00000359197.9
ENST00000349824.8
ENST00000343574.9
ENST00000357364.8
ENST00000440768.6
ENST00000346667.8
ENST00000615491.4
IKAROS family zinc finger 1
chr11_-_65047861 4.51 ENST00000533842.5
ENST00000532802.5
ENST00000530139.2
ENST00000526516.5
N-acetylated alpha-linked acidic dipeptidase like 1
chr20_+_32052192 4.16 ENST00000375862.7
ENST00000629881.2
ENST00000375852.5
ENST00000520553.5
ENST00000518730.5
HCK proto-oncogene, Src family tyrosine kinase
chr14_-_106374129 4.04 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr6_-_31582415 4.03 ENST00000429299.3
ENST00000446745.2
lymphotoxin beta
chr1_-_206921867 3.80 ENST00000628511.2
ENST00000367091.8
Fc fragment of IgM receptor
chr16_+_28985043 3.78 ENST00000395456.7
ENST00000564277.5
ENST00000630764.2
ENST00000354453.7
linker for activation of T cells
chr12_+_4273751 3.65 ENST00000675880.1
ENST00000261254.8
cyclin D2
chr22_-_37244237 3.64 ENST00000401529.3
ENST00000249071.11
Rac family small GTPase 2
chr11_-_128522285 3.63 ENST00000319397.6
ENST00000535549.5
ETS proto-oncogene 1, transcription factor
chr2_+_203936755 3.44 ENST00000316386.11
ENST00000435193.1
inducible T cell costimulator
chr1_-_206921987 3.20 ENST00000530505.1
ENST00000442471.4
Fc fragment of IgM receptor
chrX_-_154371210 3.13 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chr2_-_174597795 3.10 ENST00000679041.1
WAS/WASL interacting protein family member 1
chr16_+_50246109 3.02 ENST00000564965.5
ENST00000564044.5
adenylate cyclase 7
chr2_+_74549026 2.98 ENST00000409429.5
docking protein 1
chr16_-_726431 2.89 ENST00000345165.10
ENST00000650995.1
ENST00000293889.10
coiled-coil domain containing 78
chr2_-_174597728 2.87 ENST00000409891.5
ENST00000410117.5
WAS/WASL interacting protein family member 1
chr22_-_37244417 2.81 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
Rac family small GTPase 2
chr13_+_41457543 2.78 ENST00000379359.4
regulator of cell cycle
chr4_+_101790717 2.78 ENST00000508653.5
ENST00000322953.9
B cell scaffold protein with ankyrin repeats 1
chr22_+_37051731 2.74 ENST00000610767.4
ENST00000402077.7
ENST00000403888.7
potassium channel tetramerization domain containing 17
chr3_-_49029378 2.71 ENST00000442157.2
ENST00000326739.9
ENST00000677010.1
ENST00000678724.1
ENST00000429182.6
inosine monophosphate dehydrogenase 2
chr12_+_64610511 2.68 ENST00000336061.2
Ras association domain family member 3
chr6_+_33075952 2.66 ENST00000418931.7
major histocompatibility complex, class II, DP beta 1
chr1_-_183635659 2.61 ENST00000367534.5
ENST00000294742.6
actin related protein 2/3 complex subunit 5
chr7_+_74209989 2.59 ENST00000361082.7
ENST00000275635.11
ENST00000460943.6
ENST00000470709.1
linker for activation of T cells family member 2
chr11_-_128522264 2.55 ENST00000531611.5
ETS proto-oncogene 1, transcription factor
chr12_+_64610458 2.53 ENST00000542104.6
Ras association domain family member 3
chrX_+_13569593 2.49 ENST00000361306.6
ENST00000380602.3
EGF like domain multiple 6
chr9_-_133149334 2.45 ENST00000393160.7
ral guanine nucleotide dissociation stimulator
chr14_-_24634160 2.43 ENST00000616551.1
ENST00000382542.5
ENST00000216341.9
ENST00000526004.1
ENST00000415355.7
granzyme B
chr15_+_81196871 2.42 ENST00000559383.5
ENST00000394660.6
ENST00000683961.1
interleukin 16
chr12_+_6951345 2.39 ENST00000318974.14
ENST00000541698.5
ENST00000542462.1
protein tyrosine phosphatase non-receptor type 6
chr2_-_191150971 2.36 ENST00000409995.5
ENST00000392320.7
signal transducer and activator of transcription 4
chr4_+_101790607 2.34 ENST00000428908.5
B cell scaffold protein with ankyrin repeats 1
chr2_-_174598206 2.31 ENST00000392546.6
ENST00000436221.1
WAS/WASL interacting protein family member 1
chr1_-_183635776 2.29 ENST00000359856.11
actin related protein 2/3 complex subunit 5
chr13_+_42574145 2.28 ENST00000398795.7
ENST00000544862.5
ENST00000239849.8
TNF superfamily member 11
chr9_+_79571956 2.20 ENST00000376552.8
TLE family member 4, transcriptional corepressor
chr12_-_54984667 2.20 ENST00000524668.5
ENST00000533607.1
ENST00000449076.6
thymocyte expressed, positive selection associated 1
chr12_+_6951271 2.19 ENST00000456013.5
protein tyrosine phosphatase non-receptor type 6
chr2_+_30231524 2.17 ENST00000395323.9
ENST00000406087.5
ENST00000404397.5
LBH regulator of WNT signaling pathway
chr1_-_201507116 2.16 ENST00000340006.7
ENST00000526256.5
ENST00000526723.5
ENST00000524951.5
cysteine and glycine rich protein 1
chr14_+_63204859 2.13 ENST00000555125.1
ras homolog family member J
chr5_-_81751022 2.09 ENST00000509013.2
ENST00000505980.5
ENST00000509053.5
single stranded DNA binding protein 2
chr14_+_30874541 2.02 ENST00000396618.9
ENST00000644874.2
ENST00000555117.2
ENST00000475087.5
cochlin
chr3_+_127672925 2.00 ENST00000232744.13
ENST00000453791.6
ankyrin repeat and BTB domain containing 1
chr3_+_46979659 1.98 ENST00000450053.8
neurobeachin like 2
chr5_-_81751103 1.97 ENST00000514493.5
ENST00000320672.8
ENST00000615665.4
single stranded DNA binding protein 2
chr5_-_159209503 1.96 ENST00000424310.7
ENST00000611185.4
ring finger protein 145
chr9_+_79571767 1.96 ENST00000376544.7
TLE family member 4, transcriptional corepressor
chr6_+_41638438 1.92 ENST00000441667.5
ENST00000230321.11
ENST00000373050.8
ENST00000446650.1
ENST00000435476.1
MyoD family inhibitor
chr12_-_54384687 1.91 ENST00000550120.1
ENST00000547210.5
ENST00000394313.7
zinc finger protein 385A
chr1_-_167090370 1.90 ENST00000367868.4
glycoprotein A33
chr3_-_108222383 1.86 ENST00000264538.4
intraflagellar transport 57
chr17_-_8965674 1.86 ENST00000447110.6
ENST00000611902.4
ENST00000616147.4
ENST00000623421.3
phosphoinositide-3-kinase regulatory subunit 5
chr1_-_25905989 1.85 ENST00000399728.5
stathmin 1
chr2_+_98444835 1.85 ENST00000409016.8
ENST00000409463.5
ENST00000074304.9
ENST00000409851.8
ENST00000409540.7
inositol polyphosphate-4-phosphatase type I A
chr2_-_101308681 1.83 ENST00000295317.4
ring finger protein 149
chr6_-_32190170 1.82 ENST00000375050.6
PBX homeobox 2
chr1_-_201946469 1.79 ENST00000367288.5
leiomodin 1
chr19_-_14206168 1.79 ENST00000361434.7
ENST00000340736.10
adhesion G protein-coupled receptor L1
chr17_+_20009320 1.75 ENST00000679049.1
ENST00000472876.5
ENST00000583528.6
ENST00000680019.1
ENST00000681593.1
ENST00000395527.8
ENST00000583482.7
ENST00000679255.1
ENST00000681202.1
ENST00000677914.1
sperm antigen with calponin homology and coiled-coil domains 1
chr7_-_132576493 1.75 ENST00000321063.8
plexin A4
chr1_-_201946571 1.74 ENST00000616739.1
leiomodin 1
chr6_-_6007511 1.74 ENST00000616243.1
neuritin 1
chr1_-_25906411 1.74 ENST00000455785.7
stathmin 1
chr22_-_38700920 1.74 ENST00000456626.1
ENST00000412832.1
ENST00000683374.1
Josephin domain containing 1
chr2_+_30232150 1.72 ENST00000401506.1
ENST00000407930.2
LBH regulator of WNT signaling pathway
chr9_-_127569011 1.69 ENST00000373312.4
niban apoptosis regulator 2
chr12_+_6951250 1.68 ENST00000538715.5
protein tyrosine phosphatase non-receptor type 6
chr22_+_37051787 1.67 ENST00000456470.1
potassium channel tetramerization domain containing 17
chrX_-_101659796 1.67 ENST00000431597.5
ENST00000458024.5
ENST00000413506.5
ENST00000440675.5
ENST00000328766.9
ENST00000356824.9
armadillo repeat containing X-linked 2
chr17_-_7393404 1.67 ENST00000575434.4
phospholipid scramblase 3
chr7_+_74209947 1.65 ENST00000475494.5
ENST00000398475.5
linker for activation of T cells family member 2
chr9_-_129178247 1.64 ENST00000372491.4
immediate early response 5 like
chr14_+_30874745 1.63 ENST00000556908.5
ENST00000555881.5
ENST00000460581.6
ENST00000643575.1
cochlin
chr1_+_109621088 1.62 ENST00000369840.7
ENST00000358729.9
ENST00000476688.3
adenosine monophosphate deaminase 2
chr22_-_37953541 1.59 ENST00000422191.1
ENST00000249079.6
ENST00000403305.6
ENST00000418863.5
ENST00000619227.4
ENST00000403026.5
chromosome 22 open reading frame 23
chr9_-_120877167 1.58 ENST00000373896.8
ENST00000312189.10
PHD finger protein 19
chr19_-_54183556 1.56 ENST00000495279.2
membrane bound O-acyltransferase domain containing 7
chr16_+_28985251 1.53 ENST00000360872.9
ENST00000566177.5
linker for activation of T cells
chr8_-_66613208 1.52 ENST00000522677.8
MYB proto-oncogene like 1
chr8_-_73093114 1.50 ENST00000297354.7
somatomedin B and thrombospondin type 1 domain containing
chr12_+_54549586 1.49 ENST00000243052.8
phosphodiesterase 1B
chr17_+_75721451 1.49 ENST00000200181.8
integrin subunit beta 4
chr6_-_42451261 1.48 ENST00000372917.8
ENST00000340840.6
ENST00000354325.2
transcriptional regulating factor 1
chr4_-_108166289 1.48 ENST00000512172.1
lymphoid enhancer binding factor 1
chr8_+_120125093 1.47 ENST00000297848.8
ENST00000309791.8
collagen type XIV alpha 1 chain
chr2_+_24491860 1.47 ENST00000406961.5
ENST00000405141.5
nuclear receptor coactivator 1
chr22_-_38700976 1.45 ENST00000427389.5
Josephin domain containing 1
chr17_-_64020566 1.45 ENST00000578313.5
ENST00000584084.1
ENST00000579687.5
ENST00000578379.5
ENST00000578892.5
ENST00000579788.6
ENST00000412356.5
ENST00000418105.5
intercellular adhesion molecule 2
chr19_-_51723968 1.44 ENST00000222115.5
ENST00000540069.7
hyaluronan synthase 1
chr15_+_32717994 1.44 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
gremlin 1, DAN family BMP antagonist
chr3_-_52278321 1.43 ENST00000469000.5
WD repeat domain 82
chr17_+_76385256 1.42 ENST00000392496.3
sphingosine kinase 1
chr19_-_45076465 1.40 ENST00000303809.7
zinc finger protein 296
chr15_+_32718476 1.40 ENST00000652365.1
gremlin 1, DAN family BMP antagonist
chr4_-_108166715 1.39 ENST00000510624.5
lymphoid enhancer binding factor 1
chr17_-_81918134 1.38 ENST00000328666.11
sirtuin 7
chrX_-_154490650 1.38 ENST00000393587.4
ENST00000453912.1
ENST00000263512.5
solute carrier family 10 member 3
chr11_-_65872728 1.35 ENST00000528176.5
ENST00000307998.11
EGF containing fibulin extracellular matrix protein 2
chrX_+_47585212 1.35 ENST00000445623.1
TIMP metallopeptidase inhibitor 1
chr17_-_74712911 1.34 ENST00000326165.11
ENST00000583937.5
ENST00000301573.13
ENST00000469092.5
CD300 molecule like family member f
chr16_+_28985095 1.32 ENST00000454369.6
linker for activation of T cells
chr19_-_45076504 1.32 ENST00000622376.1
zinc finger protein 296
chr2_+_46543391 1.31 ENST00000482449.2
ras homolog family member Q
chr1_-_233295712 1.31 ENST00000258229.14
pecanex 2
chr12_-_79690957 1.30 ENST00000328827.9
pro-apoptotic WT1 regulator
chr16_+_11345429 1.29 ENST00000576027.1
ENST00000312499.6
ENST00000648619.1
RecQ mediated genome instability 2
chr11_+_66070256 1.29 ENST00000320580.9
phosphofurin acidic cluster sorting protein 1
chrX_-_154490614 1.28 ENST00000369649.8
ENST00000393586.1
ENST00000651600.1
solute carrier family 10 member 3
chr19_+_676385 1.28 ENST00000166139.9
follistatin like 3
chr16_-_88686453 1.27 ENST00000332281.6
snail family transcriptional repressor 3
chr14_+_56117702 1.27 ENST00000559044.5
pellino E3 ubiquitin protein ligase family member 2
chr22_-_38872206 1.26 ENST00000407418.8
ENST00000216083.6
chromobox 6
chr5_-_81751085 1.26 ENST00000515395.5
single stranded DNA binding protein 2
chr8_+_119416427 1.26 ENST00000259526.4
cellular communication network factor 3
chr12_-_15221394 1.26 ENST00000537647.5
ENST00000256953.6
ENST00000546331.5
RAS like estrogen regulated growth inhibitor
chr1_+_183636065 1.25 ENST00000304685.8
ral guanine nucleotide dissociation stimulator like 1
chr4_-_108166750 1.25 ENST00000515500.5
lymphoid enhancer binding factor 1
chr7_+_130492066 1.24 ENST00000223215.10
ENST00000437945.6
mesoderm specific transcript
chr1_+_109619827 1.23 ENST00000667949.2
ENST00000342115.8
ENST00000528667.7
adenosine monophosphate deaminase 2
chr17_+_75721471 1.22 ENST00000450894.7
integrin subunit beta 4
chr1_-_31704001 1.22 ENST00000373672.8
collagen type XVI alpha 1 chain
chr16_+_67192116 1.21 ENST00000379378.8
E2F transcription factor 4
chr7_-_132576463 1.21 ENST00000423507.6
plexin A4
chr17_-_74972714 1.21 ENST00000530857.1
HID1 domain containing
chr13_-_75537805 1.20 ENST00000626103.1
ENST00000682242.1
ENST00000355801.4
COMM domain containing 6
chr19_-_1174227 1.20 ENST00000587024.5
ENST00000361757.8
strawberry notch homolog 2
chr14_+_89955895 1.18 ENST00000393452.7
ENST00000554180.5
ENST00000335725.9
ENST00000393454.6
ENST00000553617.5
ENST00000556867.1
ENST00000553527.1
tyrosyl-DNA phosphodiesterase 1
chr11_-_417304 1.18 ENST00000397632.7
single Ig and TIR domain containing
chr1_+_39081410 1.17 ENST00000602421.5
ENST00000361689.7
microtubule actin crosslinking factor 1
chr12_+_53295506 1.15 ENST00000549759.2
ENST00000628881.2
ENST00000351500.7
ENST00000550846.5
ENST00000334478.9
ENST00000547130.6
ENST00000552742.6
prefoldin subunit 5
chr9_-_120877026 1.15 ENST00000436309.5
PHD finger protein 19
chr2_+_106065678 1.15 ENST00000238044.8
ENST00000437659.1
ECRG4 augurin precursor
chr1_+_228735431 1.14 ENST00000366691.4
ras homolog family member U
chr4_-_11428868 1.14 ENST00000002596.6
heparan sulfate-glucosamine 3-sulfotransferase 1
chr17_+_40309161 1.14 ENST00000254066.10
retinoic acid receptor alpha
chr2_-_232487820 1.13 ENST00000304546.6
endothelin converting enzyme like 1
chr3_-_108222362 1.13 ENST00000492106.1
intraflagellar transport 57
chr7_+_50304655 1.13 ENST00000646110.1
IKAROS family zinc finger 1
chr19_+_40799707 1.12 ENST00000594380.1
ENST00000593397.1
ENST00000601733.1
ENST00000593525.1
egl-9 family hypoxia inducible factor 2
chr1_-_154974324 1.11 ENST00000412170.5
SHC adaptor protein 1
chr17_-_74972742 1.11 ENST00000425042.7
ENST00000581676.1
HID1 domain containing
chr2_+_69013282 1.11 ENST00000409829.7
ANTXR cell adhesion molecule 1
chr1_-_32336224 1.10 ENST00000329421.8
MARCKS like 1
chr1_+_150549734 1.09 ENST00000674043.1
ENST00000674058.1
ADAMTS like 4
chr17_+_75721327 1.08 ENST00000579662.5
integrin subunit beta 4
chr22_-_38700655 1.07 ENST00000216039.9
Josephin domain containing 1
chr5_+_148826600 1.07 ENST00000305988.6
adrenoceptor beta 2
chr2_-_24360299 1.06 ENST00000361999.7
intersectin 2
chr1_+_28914515 1.06 ENST00000644600.1
ENST00000643173.1
ENST00000648181.1
ENST00000650265.1
ENST00000644780.1
ENST00000343067.9
ENST00000643604.1
ENST00000373797.2
erythrocyte membrane protein band 4.1
chr2_+_69013170 1.06 ENST00000303714.9
ANTXR cell adhesion molecule 1
chr1_-_25906457 1.05 ENST00000426559.6
stathmin 1
chr15_-_89655428 1.05 ENST00000394412.8
kinesin family member 7
chr1_+_5992639 1.04 ENST00000666163.1
ENST00000671676.1
ENST00000658883.1
ENST00000445501.6
ENST00000668706.1
ENST00000653262.1
ENST00000389632.9
ENST00000341524.6
ENST00000462676.3
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr19_-_4581755 1.04 ENST00000676793.1
semaphorin 6B
chr1_+_109620578 1.04 ENST00000531203.6
ENST00000256578.8
adenosine monophosphate deaminase 2
chr16_+_30201057 1.03 ENST00000569485.5
sulfotransferase family 1A member 3
chr5_+_141636941 1.02 ENST00000444782.5
ENST00000297164.8
ENST00000521367.5
RELT like 2
chr11_-_417385 1.01 ENST00000332725.7
single Ig and TIR domain containing
chr16_+_29461386 1.01 ENST00000565290.5
sulfotransferase family 1A member 4
chrX_+_49171889 1.01 ENST00000376327.6
proteolipid protein 2
chr4_-_80072563 1.00 ENST00000307333.7
ENST00000346652.10
ENST00000680913.1
ANTXR cell adhesion molecule 2
chr1_+_174877430 1.00 ENST00000392064.6
RAB GTPase activating protein 1 like
chr1_-_27914513 0.99 ENST00000313433.11
ENST00000373912.8
ENST00000444045.1
replication protein A2
chr2_+_202634960 0.99 ENST00000392238.3
family with sequence similarity 117 member B
chr1_-_31704319 0.98 ENST00000373668.7
collagen type XVI alpha 1 chain
chr15_-_38560050 0.98 ENST00000558432.5
RAS guanyl releasing protein 1
chr18_-_36129305 0.97 ENST00000269187.10
ENST00000590986.5
ENST00000440549.6
solute carrier family 39 member 6
chr1_-_154974361 0.96 ENST00000368453.8
ENST00000368450.5
SHC adaptor protein 1
chr17_+_40309189 0.96 ENST00000577646.5
retinoic acid receptor alpha
chr9_+_88388356 0.96 ENST00000375859.4
spindlin 1
chr2_-_69643152 0.93 ENST00000606389.7
AP2 associated kinase 1
chr19_+_40799501 0.92 ENST00000406058.6
ENST00000593726.5
egl-9 family hypoxia inducible factor 2
chr18_-_48409292 0.92 ENST00000589194.5
ENST00000591279.5
ENST00000590855.5
ENST00000587107.5
ENST00000588970.5
ENST00000586525.5
ENST00000592387.5
ENST00000590800.6
zinc finger and BTB domain containing 7C
chr1_-_58577244 0.92 ENST00000371225.4
tumor associated calcium signal transducer 2
chr2_-_179264757 0.92 ENST00000428443.8
SEC14 and spectrin domain containing 1
chr17_-_28951443 0.91 ENST00000268756.7
ENST00000332830.9
ENST00000584685.1
PHD finger protein 12
chr1_+_150549384 0.90 ENST00000369041.9
ENST00000271643.9
ADAMTS like 4
chr2_-_100104530 0.89 ENST00000432037.5
ENST00000673232.1
ENST00000423966.6
ENST00000409236.6
AF4/FMR2 family member 3
chr3_+_58008350 0.89 ENST00000490882.5
ENST00000358537.7
ENST00000429972.6
ENST00000682871.1
ENST00000295956.9
filamin B
chr7_-_98252117 0.89 ENST00000420697.1
ENST00000415086.5
ENST00000447648.7
tectonin beta-propeller repeat containing 1
chr14_-_24634266 0.88 ENST00000382540.5
granzyme B
chr12_+_57089094 0.88 ENST00000342556.6
ENST00000300131.8
NGFI-A binding protein 2
chr14_+_71932397 0.88 ENST00000553525.6
ENST00000555571.5
regulator of G protein signaling 6
chr22_+_29307005 0.88 ENST00000406549.7
ENST00000610653.4
ENST00000621062.4
ENST00000611648.2
ENST00000618518.3
growth arrest specific 2 like 1
chr14_+_101561351 0.85 ENST00000510508.4
iodothyronine deiodinase 3
chr19_+_5904856 0.85 ENST00000339485.4
vimentin type intermediate filament associated coiled-coil protein
chr11_-_106077313 0.85 ENST00000531837.2
ENST00000534815.1
kelch repeat and BTB domain containing 3
chr20_+_45469745 0.85 ENST00000372676.8
ENST00000217425.9
ENST00000339946.7
WAP four-disulfide core domain 2
chr14_+_23095491 0.85 ENST00000319074.6
ENST00000554203.1
chromosome 14 open reading frame 119
chr3_-_52278620 0.85 ENST00000296490.8
WD repeat domain 82
chr1_-_154974385 0.84 ENST00000366442.2
SHC adaptor protein 1
chr12_+_41437680 0.84 ENST00000649474.1
ENST00000539469.6
ENST00000298919.7
PDZ domain containing ring finger 4
chr17_-_64020544 0.83 ENST00000583366.5
intercellular adhesion molecule 2
chr6_-_30556477 0.83 ENST00000376621.8
G protein nucleolar 1 (putative)
chr15_+_40470950 0.83 ENST00000306243.7
carbohydrate sulfotransferase 14

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.9 2.8 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.9 6.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.8 2.3 GO:0071810 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.7 3.6 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.7 2.8 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.6 3.9 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.6 3.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.6 4.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.6 6.5 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.5 6.2 GO:0030578 PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.5 3.1 GO:0070889 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.5 1.4 GO:0046521 sphingoid catabolic process(GO:0046521)
0.5 1.9 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.5 1.4 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.5 2.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.4 1.3 GO:1902214 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) regulation of interleukin-4-mediated signaling pathway(GO:1902214)
0.4 2.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.4 5.1 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.4 4.2 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.4 1.2 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.4 3.3 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.4 2.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.4 1.4 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.4 1.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.4 3.9 GO:0032264 IMP salvage(GO:0032264)
0.4 3.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 4.9 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.3 2.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.3 4.6 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 3.8 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.3 0.9 GO:0070377 negative regulation of ERK5 cascade(GO:0070377)
0.3 1.2 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.3 0.3 GO:0033122 negative regulation of purine nucleotide catabolic process(GO:0033122)
0.3 3.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.2 2.7 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 0.7 GO:0006196 AMP catabolic process(GO:0006196)
0.2 1.5 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.2 1.5 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.2 3.8 GO:0035878 nail development(GO:0035878)
0.2 2.9 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 1.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 1.0 GO:0032252 secretory granule localization(GO:0032252)
0.2 2.8 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 0.5 GO:0032824 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.2 0.9 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 0.7 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.2 3.4 GO:0002517 T cell tolerance induction(GO:0002517)
0.2 0.8 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2 0.2 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.2 2.8 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.7 GO:0045337 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.4 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 1.0 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.6 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.1 2.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.9 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.1 1.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.8 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 10.9 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.1 1.5 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 1.3 GO:1905049 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164) negative regulation of metallopeptidase activity(GO:1905049)
0.1 3.7 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 1.9 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 3.0 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.8 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 4.0 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.8 GO:1905123 regulation of glucosylceramidase activity(GO:1905123)
0.1 1.0 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.7 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 1.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.3 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 1.1 GO:0003190 atrioventricular valve formation(GO:0003190)
0.1 3.0 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.4 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 0.4 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 0.3 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.1 1.9 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.1 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 1.2 GO:0000012 single strand break repair(GO:0000012)
0.1 0.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 1.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.1 1.4 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.9 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 2.0 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 3.4 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1 7.0 GO:0006968 cellular defense response(GO:0006968)
0.1 2.2 GO:0033622 integrin activation(GO:0033622)
0.1 1.6 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 0.8 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 1.0 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 3.8 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 1.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 1.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.2 GO:0070986 left/right axis specification(GO:0070986)
0.1 1.7 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 3.0 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.1 0.4 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.6 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.1 1.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.2 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 2.0 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 2.2 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.5 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.3 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 2.0 GO:0030220 platelet formation(GO:0030220)
0.0 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 10.1 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.7 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 1.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 7.7 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 1.3 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.2 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.9 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 1.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.4 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 1.6 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 1.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.0 1.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 2.3 GO:0046677 response to antibiotic(GO:0046677)
0.0 1.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 1.3 GO:0000732 strand displacement(GO:0000732)
0.0 1.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 1.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 3.0 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.9 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 2.7 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 1.0 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 1.0 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 1.1 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 1.0 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.1 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 1.8 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.2 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.5 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 1.0 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 2.3 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 1.6 GO:0032526 response to retinoic acid(GO:0032526)
0.0 3.4 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 1.3 GO:0035690 cellular response to drug(GO:0035690)
0.0 2.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.4 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.5 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.5 1.9 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.5 3.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.4 3.1 GO:0031523 Myb complex(GO:0031523)
0.4 8.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.4 2.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.4 2.9 GO:0070435 Shc-EGFR complex(GO:0070435)
0.3 2.9 GO:0098536 deuterosome(GO:0098536)
0.3 11.8 GO:0042629 mast cell granule(GO:0042629)
0.3 0.8 GO:1905103 integral component of lysosomal membrane(GO:1905103)
0.3 1.0 GO:0035517 PR-DUB complex(GO:0035517)
0.2 3.7 GO:0005593 FACIT collagen trimer(GO:0005593)
0.2 0.6 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 4.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 3.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 4.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 3.0 GO:0044292 dendrite terminus(GO:0044292)
0.2 0.7 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 1.0 GO:1990031 pinceau fiber(GO:1990031)
0.1 1.2 GO:0016272 prefoldin complex(GO:0016272)
0.1 3.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 2.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 2.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.5 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.4 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.5 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.1 2.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 4.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 19.9 GO:0005884 actin filament(GO:0005884)
0.1 3.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.9 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.6 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 7.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.5 GO:0089701 U2AF(GO:0089701)
0.1 0.4 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 2.0 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 3.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 7.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 3.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.1 GO:0072563 endothelial microparticle(GO:0072563)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 1.5 GO:0097542 ciliary tip(GO:0097542)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 2.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 2.0 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 2.8 GO:0005903 brush border(GO:0005903)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 7.6 GO:0005874 microtubule(GO:0005874)
0.0 0.2 GO:0005721 pericentric heterochromatin(GO:0005721)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0033142 progesterone receptor binding(GO:0033142)
0.6 1.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.5 2.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.4 9.6 GO:0005522 profilin binding(GO:0005522)
0.4 3.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4 2.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 1.8 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.4 1.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.3 3.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.3 1.4 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.3 1.3 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.3 1.8 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.3 3.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.3 1.2 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.3 3.8 GO:0038132 neuregulin binding(GO:0038132)
0.3 1.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 2.9 GO:0048408 epidermal growth factor binding(GO:0048408)
0.3 4.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.3 1.0 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.2 0.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 1.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 2.9 GO:0036122 BMP binding(GO:0036122)
0.2 1.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 0.6 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.2 1.4 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 0.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 1.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 2.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 0.8 GO:1903135 cupric ion binding(GO:1903135)
0.2 1.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 0.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 1.7 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 0.7 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 4.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 3.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.9 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 10.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.5 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 3.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 4.5 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 6.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 3.5 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.8 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.3 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 0.3 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 1.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 2.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.3 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.1 6.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.7 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.7 GO:0043426 MRF binding(GO:0043426)
0.1 0.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 2.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 7.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 2.7 GO:0042605 peptide antigen binding(GO:0042605)
0.1 4.2 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.6 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 1.3 GO:0048185 activin binding(GO:0048185)
0.1 1.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 2.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.5 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 1.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 6.5 GO:0005518 collagen binding(GO:0005518)
0.0 4.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 2.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 5.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 4.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.9 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 5.0 GO:0005178 integrin binding(GO:0005178)
0.0 2.8 GO:0002039 p53 binding(GO:0002039)
0.0 1.0 GO:0019956 chemokine binding(GO:0019956)
0.0 0.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 1.0 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 4.0 GO:0003823 antigen binding(GO:0003823)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 5.8 GO:0003924 GTPase activity(GO:0003924)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 12.6 PID BCR 5PATHWAY BCR signaling pathway
0.2 3.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 4.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 10.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 19.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 12.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 6.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 3.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 3.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 4.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 5.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 6.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 3.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 2.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 2.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.9 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 5.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 2.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 5.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.9 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 5.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 1.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 6.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 3.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 5.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.9 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 0.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 3.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 4.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 1.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 2.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.6 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 3.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 3.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 3.6 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 1.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 7.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 3.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.2 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.7 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 1.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 2.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.7 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.0 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 1.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.5 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway