Project

Illumina Body Map 2 (GSE30611)

Navigation
Downloads

Results for HNF4A

Z-value: 3.95

Motif logo

Transcription factors associated with HNF4A

Gene Symbol Gene ID Gene Info
ENSG00000101076.18 hepatocyte nuclear factor 4 alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF4Ahg38_v1_chr20_+_44401269_444013010.931.2e-14Click!

Activity profile of HNF4A motif

Sorted Z-values of HNF4A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_101442403 32.54 ENST00000648758.1
aldolase, fructose-bisphosphate B
chr10_+_94938649 29.04 ENST00000461906.1
ENST00000260682.8
cytochrome P450 family 2 subfamily C member 9
chr10_-_95069489 27.90 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
cytochrome P450 family 2 subfamily C member 8
chr9_+_136945234 26.11 ENST00000371634.7
complement C8 gamma chain
chr20_+_57561103 25.98 ENST00000319441.6
phosphoenolpyruvate carboxykinase 1
chr3_-_42875871 25.79 ENST00000316161.6
ENST00000437102.1
cytochrome P450 family 8 subfamily B member 1
chr17_+_42900791 25.13 ENST00000592383.5
ENST00000253801.7
ENST00000585489.1
glucose-6-phosphatase catalytic subunit 1
chr10_-_127892930 24.97 ENST00000368671.4
clarin 3
chr9_-_101442372 24.62 ENST00000648423.1
aldolase, fructose-bisphosphate B
chr17_+_29043124 24.15 ENST00000323372.9
pipecolic acid and sarcosine oxidase
chr17_+_4771878 23.63 ENST00000270560.4
transmembrane 4 L six family member 5
chr6_+_31946086 23.37 ENST00000425368.7
complement factor B
chr1_-_161223559 23.09 ENST00000469730.2
ENST00000463273.5
ENST00000464492.5
ENST00000367990.7
ENST00000470459.6
ENST00000463812.1
ENST00000468465.5
apolipoprotein A2
chr3_-_120682215 22.47 ENST00000283871.10
homogentisate 1,2-dioxygenase
chr5_-_35047935 22.46 ENST00000510428.1
ENST00000231420.11
alanine--glyoxylate aminotransferase 2
chr19_+_44946043 21.81 ENST00000252490.7
ENST00000591597.5
apolipoprotein C2
chr19_+_44946009 21.44 ENST00000592257.5
apolipoprotein C2
chr17_-_7179348 21.37 ENST00000573083.1
ENST00000574388.5
ENST00000269299.8
asialoglycoprotein receptor 1
chr11_-_116823293 20.66 ENST00000357780.5
apolipoprotein A4
chr12_+_55681711 20.19 ENST00000394252.4
methyltransferase like 7B
chr1_-_145707345 19.68 ENST00000417171.6
PDZ domain containing 1
chr17_-_7179544 19.27 ENST00000619926.4
asialoglycoprotein receptor 1
chr12_+_55681647 18.94 ENST00000614691.1
methyltransferase like 7B
chr1_-_145707387 18.85 ENST00000451928.6
PDZ domain containing 1
chr3_-_120682113 18.84 ENST00000476082.2
homogentisate 1,2-dioxygenase
chr1_-_15585015 18.74 ENST00000375826.4
agmatinase
chr3_-_194351290 18.50 ENST00000429275.1
ENST00000323830.4
carboxypeptidase N subunit 2
chr20_-_7940444 18.11 ENST00000378789.4
hydroxyacid oxidase 1
chr6_+_43298254 17.94 ENST00000372585.10
ENST00000449231.5
ENST00000372589.7
solute carrier family 22 member 7
chr10_+_94683722 17.70 ENST00000285979.11
cytochrome P450 family 2 subfamily C member 18
chr10_+_94762673 17.68 ENST00000480405.2
ENST00000371321.9
cytochrome P450 family 2 subfamily C member 19
chr6_+_130827398 17.23 ENST00000541421.2
small leucine rich protein 1
chr6_+_31982057 17.08 ENST00000428956.7
ENST00000498271.1
complement C4A (Rodgers blood group)
chr6_+_32014795 16.46 ENST00000435363.7
ENST00000425700.3
complement C4B (Chido blood group)
chr10_+_94683771 15.82 ENST00000339022.6
cytochrome P450 family 2 subfamily C member 18
chr1_-_161223408 15.63 ENST00000491350.1
apolipoprotein A2
chr19_-_38812936 15.50 ENST00000307751.9
ENST00000594209.1
galectin 4
chr1_-_146021724 15.09 ENST00000475797.1
ENST00000497365.5
ENST00000336751.11
ENST00000634927.1
ENST00000421822.2
hemojuvelin BMP co-receptor
chr1_-_177969907 14.76 ENST00000308284.10
SEC16 homolog B, endoplasmic reticulum export factor
chr19_-_58511981 14.38 ENST00000263093.7
ENST00000601355.1
solute carrier family 27 member 5
chr16_-_16223467 14.37 ENST00000575728.1
ENST00000574094.6
ENST00000205557.12
ATP binding cassette subfamily C member 6
chr13_+_113105782 14.21 ENST00000541084.5
ENST00000346342.8
ENST00000375581.3
coagulation factor VII
chr17_-_37745018 14.21 ENST00000613727.4
ENST00000614313.4
ENST00000617811.5
ENST00000621123.4
HNF1 homeobox B
chr16_+_8674605 13.51 ENST00000268251.13
4-aminobutyrate aminotransferase
chr3_+_46497970 12.93 ENST00000296142.4
receptor transporter protein 3
chr17_+_1742836 12.92 ENST00000324015.7
ENST00000450523.6
ENST00000453723.5
ENST00000453066.6
ENST00000382061.5
serpin family F member 2
chr3_+_119782094 12.76 ENST00000393716.8
nuclear receptor subfamily 1 group I member 2
chr2_+_44275491 12.66 ENST00000410056.7
ENST00000409741.5
ENST00000409229.7
solute carrier family 3 member 1
chr1_-_161238085 12.44 ENST00000512372.5
ENST00000437437.6
ENST00000412844.6
ENST00000428574.6
ENST00000442691.6
ENST00000505005.5
ENST00000508740.5
ENST00000367981.7
ENST00000502985.5
ENST00000504010.5
ENST00000508387.5
ENST00000511676.5
ENST00000511748.5
ENST00000511944.5
ENST00000515621.5
ENST00000367984.8
ENST00000367985.7
nuclear receptor subfamily 1 group I member 3
chr1_-_155301423 12.18 ENST00000342741.6
pyruvate kinase L/R
chr19_-_14062028 11.98 ENST00000669674.2
paralemmin 3
chr9_-_133739920 11.87 ENST00000371872.8
ENST00000298628.6
sarcosine dehydrogenase
chr7_+_45888479 11.77 ENST00000275525.8
ENST00000468955.1
insulin like growth factor binding protein 1
chr2_+_44275457 11.73 ENST00000611973.4
ENST00000409387.5
solute carrier family 3 member 1
chr1_+_196888014 11.35 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
complement factor H related 4
chr12_+_57454674 11.13 ENST00000547970.1
inhibin subunit beta E
chr6_+_30163541 10.97 ENST00000376694.9
tripartite motif containing 15
chr12_+_108880085 10.85 ENST00000228476.8
ENST00000547768.5
D-amino acid oxidase
chr19_-_35812838 10.68 ENST00000653904.2
proline dehydrogenase 2
chr1_-_155300979 10.68 ENST00000392414.7
pyruvate kinase L/R
chr22_-_42130800 10.63 ENST00000645361.2
ENST00000359033.4
cytochrome P450 family 2 subfamily D member 6
chr2_-_27890348 10.38 ENST00000302188.8
ribokinase
chr19_+_15641280 9.61 ENST00000585846.1
cytochrome P450 family 4 subfamily F member 3
chrX_+_38352573 9.57 ENST00000039007.5
ornithine transcarbamylase
chr16_+_29679132 9.49 ENST00000395384.9
ENST00000562473.1
quinolinate phosphoribosyltransferase
chr2_-_21043941 9.49 ENST00000399256.4
apolipoprotein B
chr11_+_63369779 9.35 ENST00000279178.4
solute carrier family 22 member 9
chr7_+_45888360 9.20 ENST00000457280.5
insulin like growth factor binding protein 1
chr19_+_44613558 9.04 ENST00000402988.6
immunoglobulin superfamily member 23
chr12_+_120978686 9.00 ENST00000541395.5
ENST00000544413.2
HNF1 homeobox A
chr19_+_7595830 8.96 ENST00000160298.9
ENST00000446248.4
calmodulin regulated spectrin associated protein family member 3
chr2_-_31414694 8.62 ENST00000379416.4
xanthine dehydrogenase
chr5_-_42811884 8.59 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr7_-_15561986 8.52 ENST00000342526.8
alkylglycerol monooxygenase
chr17_+_4788926 8.35 ENST00000331264.8
glycolipid transfer protein domain containing 2
chr6_+_43298326 8.22 ENST00000372574.7
solute carrier family 22 member 7
chr1_-_161238196 8.07 ENST00000367983.9
ENST00000506209.5
ENST00000367980.6
ENST00000628566.2
nuclear receptor subfamily 1 group I member 3
chr6_+_30163188 8.00 ENST00000619857.4
tripartite motif containing 15
chr4_-_87322845 7.89 ENST00000328546.5
ENST00000302219.10
hydroxysteroid 17-beta dehydrogenase 13
chr19_+_41088450 7.88 ENST00000330436.4
cytochrome P450 family 2 subfamily A member 13
chr7_-_87475839 7.57 ENST00000359206.8
ATP binding cassette subfamily B member 4
chr12_+_120978537 7.46 ENST00000257555.11
ENST00000400024.6
HNF1 homeobox A
chr1_-_201399525 7.41 ENST00000367313.4
ladinin 1
chr5_+_90899183 7.32 ENST00000640815.1
adhesion G protein-coupled receptor V1
chr14_+_102922639 7.24 ENST00000299155.10
amnion associated transmembrane protein
chr11_+_27055215 7.24 ENST00000525090.1
gamma-butyrobetaine hydroxylase 1
chr3_+_46877705 6.73 ENST00000449590.6
parathyroid hormone 1 receptor
chr1_-_197067234 6.71 ENST00000367412.2
coagulation factor XIII B chain
chr2_-_42792558 6.71 ENST00000431905.1
ENST00000294973.11
3-hydroxyanthranilate 3,4-dioxygenase
chr7_-_87475647 6.50 ENST00000649586.2
ENST00000265723.8
ATP binding cassette subfamily B member 4
chr1_-_177970213 6.49 ENST00000464631.6
SEC16 homolog B, endoplasmic reticulum export factor
chr1_-_161238223 6.39 ENST00000515452.1
nuclear receptor subfamily 1 group I member 3
chr16_+_8674584 6.29 ENST00000564714.5
4-aminobutyrate aminotransferase
chr1_+_6448022 6.26 ENST00000416731.5
ENST00000461727.6
espin
chr3_-_187291680 6.17 ENST00000425937.1
ENST00000337774.10
ENST00000296280.11
mannan binding lectin serine peptidase 1
chr1_+_94418375 6.03 ENST00000370214.9
ATP binding cassette subfamily D member 3
chr17_+_28744034 5.99 ENST00000444415.7
ENST00000262396.10
TNF receptor associated factor 4
chr11_-_63229652 5.72 ENST00000306494.10
solute carrier family 22 member 25
chr5_+_177384430 5.64 ENST00000512593.5
ENST00000324417.6
solute carrier family 34 member 1
chr1_+_94418435 5.57 ENST00000647998.2
ATP binding cassette subfamily D member 3
chr11_-_66718817 5.49 ENST00000617502.5
spectrin beta, non-erythrocytic 2
chr17_-_46818680 5.41 ENST00000225512.6
Wnt family member 3
chr3_-_53844617 5.37 ENST00000481668.5
ENST00000467802.1
choline dehydrogenase
chr16_-_87936529 5.37 ENST00000649794.3
ENST00000649158.1
ENST00000648177.1
carbonic anhydrase 5A
chr17_+_79730937 5.30 ENST00000328313.10
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr2_-_46462 5.20 ENST00000327669.5
family with sequence similarity 110 member C
chr13_+_113122791 5.15 ENST00000375559.8
ENST00000409306.5
ENST00000375551.7
coagulation factor X
chr2_+_44275473 5.12 ENST00000260649.11
solute carrier family 3 member 1
chr1_+_78045956 5.09 ENST00000370759.4
GIPC PDZ domain containing family member 2
chr19_+_10086305 4.98 ENST00000253110.16
ENST00000591813.5
shiftless antiviral inhibitor of ribosomal frameshifting
chr16_+_21233672 4.95 ENST00000311620.7
ankyrin repeat and sterile alpha motif domain containing 4B
chr1_-_161238163 4.92 ENST00000367982.8
nuclear receptor subfamily 1 group I member 3
chr1_-_23800402 4.91 ENST00000374497.7
ENST00000425913.5
UDP-galactose-4-epimerase
chr10_+_100347225 4.84 ENST00000370355.3
stearoyl-CoA desaturase
chr3_-_187291882 4.81 ENST00000392470.6
ENST00000169293.10
ENST00000439271.1
ENST00000392472.6
ENST00000392475.2
mannan binding lectin serine peptidase 1
chr22_+_24607658 4.76 ENST00000451366.5
ENST00000428855.5
gamma-glutamyltransferase 1
chr1_-_23800745 4.69 ENST00000617979.5
ENST00000418277.5
UDP-galactose-4-epimerase
chr2_+_119679154 4.60 ENST00000401466.5
ENST00000424086.5
transmembrane protein 177
chr4_-_10021490 4.57 ENST00000264784.8
solute carrier family 2 member 9
chr14_+_39267055 4.52 ENST00000396158.6
ENST00000280083.7
ENST00000341502.9
MIA SH3 domain ER export factor 2
chr8_-_81695045 4.49 ENST00000518568.3
solute carrier family 10 member 5
chr11_+_75159780 4.20 ENST00000525845.5
ENST00000534186.5
ENST00000428359.6
solute carrier organic anion transporter family member 2B1
chr1_+_94418467 4.18 ENST00000315713.5
ATP binding cassette subfamily D member 3
chr1_+_200027702 4.17 ENST00000367362.8
nuclear receptor subfamily 5 group A member 2
chr3_-_124934735 4.17 ENST00000478191.1
ENST00000616727.4
mucin 13, cell surface associated
chr2_+_119679184 4.15 ENST00000445518.1
ENST00000272521.7
ENST00000409951.1
transmembrane protein 177
chr1_-_201399906 4.01 ENST00000631576.1
ladinin 1
chr1_-_155300933 3.87 ENST00000434082.3
pyruvate kinase L/R
chr2_+_218270392 3.85 ENST00000248451.7
ENST00000273077.9
PNKD metallo-beta-lactamase domain containing
chr20_+_38033719 3.50 ENST00000373433.9
regulation of nuclear pre-mRNA domain containing 1B
chr19_+_10086787 3.49 ENST00000590378.5
ENST00000397881.7
shiftless antiviral inhibitor of ribosomal frameshifting
chrX_+_118974608 3.45 ENST00000304778.11
ENST00000371628.8
LON peptidase N-terminal domain and ring finger 3
chr17_-_49709014 3.41 ENST00000511657.1
solute carrier family 35 member B1
chr14_+_38207893 3.37 ENST00000267377.3
somatostatin receptor 1
chrX_-_43882411 3.28 ENST00000378069.5
monoamine oxidase B
chr1_+_241532121 3.18 ENST00000366558.7
kynurenine 3-monooxygenase
chr1_+_200027605 3.15 ENST00000236914.7
nuclear receptor subfamily 5 group A member 2
chr11_+_119185469 3.10 ENST00000525131.5
ENST00000355547.10
ENST00000531114.5
ENST00000322712.4
PDZ domain containing 3
chr17_-_17591658 3.02 ENST00000435340.6
ENST00000255389.10
ENST00000395781.6
phosphatidylethanolamine N-methyltransferase
chr22_+_24607638 3.00 ENST00000432867.5
gamma-glutamyltransferase 1
chr1_+_6447331 2.98 ENST00000632803.1
ENST00000632593.1
espin
chr9_-_113303271 2.93 ENST00000297894.5
ENST00000489339.2
ring finger protein 183
chr12_-_7018465 2.92 ENST00000261407.9
lysophosphatidylcholine acyltransferase 3
chr22_+_24607602 2.89 ENST00000447416.5
gamma-glutamyltransferase 1
chr1_+_241532370 2.88 ENST00000366559.9
ENST00000366557.8
kynurenine 3-monooxygenase
chr16_-_57480366 2.78 ENST00000562008.5
ENST00000567214.5
docking protein 4
chr5_+_73173186 2.72 ENST00000296776.6
transmembrane protein 174
chr1_-_43285559 2.70 ENST00000523677.6
chromosome 1 open reading frame 210
chr14_-_22976812 2.55 ENST00000553592.5
ajuba LIM protein
chr17_-_2711633 2.50 ENST00000435359.5
clustered mitochondria homolog
chr15_-_40828699 2.44 ENST00000299174.10
ENST00000427255.2
protein phosphatase 1 regulatory inhibitor subunit 14D
chr11_-_63768641 2.42 ENST00000546282.3
chromosome 11 open reading frame 95
chr19_-_35852495 2.38 ENST00000378910.10
NPHS1 adhesion molecule, nephrin
chr7_+_100949525 2.15 ENST00000379458.9
ENST00000483366.5
mucin 3A, cell surface associated
chr7_-_47581631 2.08 ENST00000434451.1
tensin 3
chr7_-_126533850 1.98 ENST00000444921.3
glutamate metabotropic receptor 8
chr13_+_75760431 1.87 ENST00000321797.12
LIM domain 7
chr1_-_43285606 1.86 ENST00000423420.1
chromosome 1 open reading frame 210
chr13_+_75760659 1.78 ENST00000526202.5
ENST00000465261.6
LIM domain 7
chr17_-_3636239 1.77 ENST00000225519.5
sedoheptulokinase
chr22_+_37024137 1.73 ENST00000628507.1
mercaptopyruvate sulfurtransferase
chr1_+_112674722 1.65 ENST00000357443.2
Mov10 RISC complex RNA helicase
chr8_+_95024977 1.58 ENST00000396124.9
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr1_+_112674416 1.57 ENST00000413052.6
ENST00000369645.5
Mov10 RISC complex RNA helicase
chr2_-_158456702 1.55 ENST00000409889.1
ENST00000283233.10
coiled-coil domain containing 148
chr17_-_2711736 1.53 ENST00000651024.2
ENST00000576885.5
ENST00000574426.7
clustered mitochondria homolog
chr12_+_53103479 1.49 ENST00000301466.8
ENST00000551896.5
sterol O-acyltransferase 2
chr9_-_68540879 1.48 ENST00000377311.4
transmembrane protein 252
chr20_+_59300547 1.43 ENST00000644821.1
endothelin 3
chr2_-_62506136 1.42 ENST00000335390.6
transmembrane protein 17
chr15_+_21651844 1.40 ENST00000623441.1
olfactory receptor family 4 subfamily N member 4C
chr19_-_48364034 1.36 ENST00000435956.7
transmembrane protein 143
chr5_-_16508990 1.34 ENST00000399793.6
reticulophagy regulator 1
chr19_-_48363914 1.32 ENST00000377431.6
ENST00000293261.8
transmembrane protein 143
chr1_+_112674649 1.31 ENST00000369644.5
Mov10 RISC complex RNA helicase
chr13_-_52011337 1.24 ENST00000400366.6
ENST00000400370.8
ENST00000634844.1
ENST00000673772.1
ENST00000418097.7
ENST00000242839.10
ENST00000344297.9
ENST00000448424.7
ATPase copper transporting beta
chr15_+_22094522 1.22 ENST00000328795.5
olfactory receptor family 4 subfamily N member 4
chr6_+_30914329 1.11 ENST00000541562.6
valyl-tRNA synthetase 2, mitochondrial
chr15_+_100602519 1.09 ENST00000332783.12
ENST00000558747.5
ENST00000343276.4
ankyrin repeat and SOCS box containing 7
chr5_-_16508788 1.03 ENST00000682142.1
reticulophagy regulator 1
chr19_+_35138993 1.01 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr19_+_751104 1.00 ENST00000215582.8
mitotic spindle positioning
chr14_-_22976793 0.98 ENST00000553911.1
ajuba LIM protein
chr8_-_78804928 0.96 ENST00000520269.5
interleukin 7
chr7_-_78771108 0.89 ENST00000626691.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_-_65614195 0.89 ENST00000309100.8
ENST00000529839.1
ENST00000526293.1
mitogen-activated protein kinase kinase kinase 11
chr19_+_35371290 0.88 ENST00000597214.1
G protein-coupled receptor 42
chr6_+_79631322 0.87 ENST00000369838.6
SH3 domain binding glutamate rich protein like 2
chr19_+_4639505 0.81 ENST00000327473.9
TNF alpha induced protein 8 like 1
chr7_-_78771058 0.79 ENST00000628781.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr16_+_83998252 0.78 ENST00000564166.1
N-terminal EF-hand calcium binding protein 2
chr20_+_59300703 0.76 ENST00000395654.3
endothelin 3
chr7_-_78770859 0.74 ENST00000636717.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr6_+_30914205 0.74 ENST00000672801.1
ENST00000321897.9
ENST00000625423.2
ENST00000676266.1
ENST00000428017.5
valyl-tRNA synthetase 2, mitochondrial
chr8_+_11982251 0.74 ENST00000382208.3
defensin beta 135
chr1_+_44808482 0.73 ENST00000450269.5
ENST00000409335.6
BTB domain containing 19
chr8_+_103819244 0.71 ENST00000262231.14
ENST00000507740.5
ENST00000408894.6
regulating synaptic membrane exocytosis 2
chr16_+_66844914 0.68 ENST00000394069.3
carbonic anhydrase 7
chr20_-_3663399 0.67 ENST00000290417.7
ENST00000319242.8
GDNF family receptor alpha 4
chr1_+_20633450 0.63 ENST00000321556.5
PTEN induced kinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF4A

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.8 43.2 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
10.2 30.7 GO:0035565 regulation of pronephros size(GO:0035565)
9.7 38.7 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
8.7 26.0 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
8.2 57.4 GO:0016098 monoterpenoid metabolic process(GO:0016098)
6.3 19.0 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
5.7 57.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
5.6 22.5 GO:0009436 glyoxylate catabolic process(GO:0009436)
5.6 27.9 GO:0002933 lipid hydroxylation(GO:0002933)
5.2 20.7 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
4.8 9.6 GO:0036101 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
4.7 14.1 GO:2001025 response to cyclosporin A(GO:1905237) positive regulation of response to drug(GO:2001025)
4.3 21.5 GO:0006562 proline catabolic process(GO:0006562)
4.1 41.3 GO:0006572 tyrosine catabolic process(GO:0006572)
4.0 24.2 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
4.0 11.9 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
3.9 15.8 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
3.5 10.4 GO:0019303 D-ribose catabolic process(GO:0019303)
3.3 29.5 GO:0015811 L-cystine transport(GO:0015811)
3.2 9.6 GO:0097272 ammonia homeostasis(GO:0097272)
3.2 22.3 GO:0046874 quinolinate metabolic process(GO:0046874)
3.1 18.7 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
3.0 26.7 GO:0042866 pyruvate biosynthetic process(GO:0042866)
2.9 8.6 GO:0046110 xanthine metabolic process(GO:0046110)
2.8 14.2 GO:1905225 response to thyrotropin-releasing hormone(GO:1905225)
2.8 19.8 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
2.7 23.9 GO:0006642 triglyceride mobilization(GO:0006642)
2.5 49.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
2.4 33.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
2.3 18.1 GO:0009441 glycolate metabolic process(GO:0009441)
2.2 41.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
2.1 12.8 GO:0042738 exogenous drug catabolic process(GO:0042738)
1.9 5.6 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
1.8 12.9 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
1.7 5.0 GO:1904106 protein localization to microvillus(GO:1904106)
1.4 5.4 GO:0060061 Spemann organizer formation(GO:0060061)
1.3 5.4 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
1.3 3.8 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
1.3 21.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
1.2 8.5 GO:0046485 ether lipid metabolic process(GO:0046485)
1.2 12.0 GO:0008063 Toll signaling pathway(GO:0008063)
1.1 15.1 GO:0015747 urate transport(GO:0015747)
1.0 38.5 GO:0015879 carnitine transport(GO:0015879)
0.9 7.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.9 9.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.9 3.4 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.8 30.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.8 3.3 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.8 10.7 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.7 3.4 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.6 0.6 GO:0036482 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.6 1.9 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.6 8.6 GO:0001887 selenium compound metabolic process(GO:0001887)
0.6 11.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.6 1.8 GO:0035963 cellular response to interleukin-13(GO:0035963)
0.6 5.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.6 19.0 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.6 7.2 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.5 9.6 GO:0019388 galactose catabolic process(GO:0019388)
0.5 9.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.4 26.0 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.4 3.5 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.4 3.4 GO:0061709 reticulophagy(GO:0061709)
0.4 40.6 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.4 1.2 GO:0060003 copper ion export(GO:0060003)
0.4 4.5 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.4 5.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.3 1.7 GO:0019346 homoserine metabolic process(GO:0009092) cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) transsulfuration(GO:0019346)
0.3 3.0 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.3 1.3 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.3 4.6 GO:0046415 urate metabolic process(GO:0046415)
0.3 12.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.3 6.0 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 29.9 GO:0030449 regulation of complement activation(GO:0030449)
0.2 3.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 6.7 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.2 29.4 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.2 2.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 4.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 0.8 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.1 4.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.9 GO:0015798 myo-inositol transport(GO:0015798)
0.1 2.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 3.5 GO:0072015 glomerular visceral epithelial cell development(GO:0072015)
0.1 0.8 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.5 GO:0061386 closure of optic fissure(GO:0061386)
0.1 1.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 1.8 GO:0015889 cobalamin transport(GO:0015889)
0.1 3.1 GO:0034389 lipid particle organization(GO:0034389)
0.1 2.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.3 GO:0036323 vascular endothelial growth factor receptor-1 signaling pathway(GO:0036323)
0.1 5.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.7 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 2.9 GO:0036152 phosphatidylserine acyl-chain remodeling(GO:0036150) phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 4.8 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.1 1.5 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.1 0.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 4.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 5.5 GO:0051693 actin filament capping(GO:0051693)
0.1 0.7 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.2 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 0.4 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 5.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 2.1 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.3 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 3.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 11.6 GO:0032259 methylation(GO:0032259)
0.0 1.0 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 13.4 GO:0042493 response to drug(GO:0042493)
0.0 0.6 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.6 52.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
2.9 26.1 GO:0005579 membrane attack complex(GO:0005579)
2.8 19.8 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
2.8 59.4 GO:0042627 chylomicron(GO:0042627)
1.1 57.2 GO:0034451 centriolar satellite(GO:0034451)
1.0 12.9 GO:0005577 fibrinogen complex(GO:0005577)
0.9 69.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.9 14.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.9 38.5 GO:0031528 microvillus membrane(GO:0031528)
0.4 44.9 GO:0031526 brush border membrane(GO:0031526)
0.4 8.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.4 9.2 GO:0032426 stereocilium tip(GO:0032426)
0.4 8.6 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.4 9.0 GO:0005915 zonula adherens(GO:0005915)
0.3 5.4 GO:1990909 Wnt signalosome(GO:1990909)
0.3 75.5 GO:0072562 blood microparticle(GO:0072562)
0.2 5.5 GO:0008091 spectrin(GO:0008091)
0.2 15.4 GO:0009925 basal plasma membrane(GO:0009925)
0.2 3.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 24.1 GO:0005796 Golgi lumen(GO:0005796)
0.2 4.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 203.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 32.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.4 GO:0032302 MutSbeta complex(GO:0032302)
0.1 11.4 GO:0005604 basement membrane(GO:0005604)
0.1 1.4 GO:0036038 MKS complex(GO:0036038)
0.1 0.6 GO:0097413 Lewy body(GO:0097413)
0.1 39.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 4.3 GO:0005902 microvillus(GO:0005902)
0.0 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 9.1 GO:0043296 apical junction complex(GO:0043296)
0.0 3.1 GO:0005811 lipid particle(GO:0005811)
0.0 2.5 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 7.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 9.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 12.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 9.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 134.0 GO:0005576 extracellular region(GO:0005576)
0.0 2.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.2 GO:0045111 intermediate filament cytoskeleton(GO:0045111)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
14.3 57.2 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
13.8 41.3 GO:0004411 homogentisate 1,2-dioxygenase activity(GO:0004411)
11.4 56.9 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
8.7 26.0 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
7.7 38.7 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
7.2 43.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
6.0 18.1 GO:0052852 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
5.3 31.8 GO:0004882 androgen receptor activity(GO:0004882)
5.1 40.6 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
4.8 24.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
4.8 38.5 GO:0005124 scavenger receptor binding(GO:0005124)
4.0 11.9 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
3.8 26.7 GO:0004743 pyruvate kinase activity(GO:0004743)
3.7 22.5 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
3.4 20.7 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
3.3 59.1 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
3.3 29.5 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
3.2 9.6 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
2.8 19.8 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
2.4 9.6 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
2.3 15.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
2.2 15.5 GO:0016936 galactoside binding(GO:0016936)
2.2 83.0 GO:0001848 complement binding(GO:0001848)
2.0 14.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
2.0 23.7 GO:0015245 fatty acid transporter activity(GO:0015245)
1.8 7.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.6 12.9 GO:0031849 olfactory receptor binding(GO:0031849)
1.6 9.5 GO:0035473 lipase binding(GO:0035473)
1.5 4.6 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.5 36.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
1.5 21.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.4 8.6 GO:0043546 molybdopterin cofactor binding(GO:0043546)
1.3 6.7 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
1.3 3.8 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
1.2 9.5 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
1.1 18.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.0 3.0 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.9 36.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.9 8.5 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.9 3.4 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.8 27.6 GO:0071949 FAD binding(GO:0071949)
0.7 4.8 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.7 14.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.7 3.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.6 4.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.6 1.9 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.6 10.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.6 8.6 GO:0008430 selenium binding(GO:0008430)
0.5 9.6 GO:0042301 phosphate ion binding(GO:0042301)
0.5 19.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 5.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.4 1.7 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.4 1.2 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.4 1.5 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.3 6.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 1.0 GO:0005139 interleukin-7 receptor binding(GO:0005139)
0.3 6.0 GO:0031996 thioesterase binding(GO:0031996)
0.3 3.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 3.8 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.3 3.1 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.2 10.4 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.2 0.8 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.2 2.9 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 20.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 3.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 5.4 GO:0005109 frizzled binding(GO:0005109)
0.1 9.0 GO:0030507 spectrin binding(GO:0030507)
0.1 33.6 GO:0008168 methyltransferase activity(GO:0008168)
0.1 0.6 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0036326 VEGF-A-activated receptor activity(GO:0036326) VEGF-B-activated receptor activity(GO:0036327) placental growth factor-activated receptor activity(GO:0036332)
0.1 10.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.4 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 12.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 11.0 GO:0005179 hormone activity(GO:0005179)
0.1 14.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 11.4 GO:0005319 lipid transporter activity(GO:0005319)
0.1 0.7 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 2.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 3.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.9 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.1 0.6 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 5.4 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.1 19.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.2 GO:0052815 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.0 2.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 2.0 GO:0008066 glutamate receptor activity(GO:0008066)
0.0 0.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.5 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.0 9.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.5 GO:0017022 myosin binding(GO:0017022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 161.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.8 23.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.4 37.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 31.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 61.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 2.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 5.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 16.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 3.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 3.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.9 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 126.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
3.7 91.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
2.7 40.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
2.1 51.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
1.4 26.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
1.2 22.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
1.2 83.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
1.1 26.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
1.0 19.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.9 26.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.9 12.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.9 18.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.9 8.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.9 11.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.7 21.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.6 6.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.6 15.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.5 14.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.5 38.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.4 19.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.4 29.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 6.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 44.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 77.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.3 10.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 8.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 4.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 4.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 2.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 4.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 3.3 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 9.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 3.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 5.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 12.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 2.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 13.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 5.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 3.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 6.8 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 0.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol