ISMARA results: HOXA4

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Illumina Body Map 2 (GSE30611)

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Results for HOXA4

Z-value: 2.03

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Transcription factors associated with HOXA4

Gene Symbol	Gene ID	Gene Info
HOXA4 Ensembl NCBI GeneCards UniProt	ENSG00000197576.14	homeobox A4

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HOXA4	hg38_v1_chr7_-_27130182_27130226	-0.31	8.6e-02	Click!

Activity profile of HOXA4 motif

Sorted Z-values of HOXA4 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr10_-_90921079 Show fit	12.46	ENST00000371697.4	ANKRD1 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 1
chr3_+_121593363 Show fit	12.18	ENST00000338040.6	FBXO40 Ensembl NCBI GeneCards UniProt Show fit	F-box protein 40
chr3_-_52452828 Show fit	8.91	ENST00000496590.1	TNNC1 Ensembl NCBI GeneCards UniProt Show fit	troponin C1, slow skeletal and cardiac type
chr1_+_160190567 Show fit	8.82	ENST00000368078.8	CASQ1 Ensembl NCBI GeneCards UniProt Show fit	calsequestrin 1
chr22_+_25742141 Show fit	8.55	ENST00000536101.5 ENST00000335473.12 ENST00000407587.6	MYO18B Ensembl NCBI GeneCards UniProt Show fit	myosin XVIIIB
chr17_-_10518536 Show fit	8.53	ENST00000226207.6	MYH1 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 1
chr2_-_178804623 Show fit	8.40	ENST00000359218.10 ENST00000342175.11	TTN Ensembl NCBI GeneCards UniProt Show fit	titin
chr10_-_73655984 Show fit	8.29	ENST00000394810.3	SYNPO2L Ensembl NCBI GeneCards UniProt Show fit	synaptopodin 2 like
chr3_-_42702778 Show fit	7.76	ENST00000457462.5 ENST00000441594.6	HHATL Ensembl NCBI GeneCards UniProt Show fit	hedgehog acyltransferase like
chr8_+_78591222 Show fit	7.36	ENST00000518467.1	PKIA Ensembl NCBI GeneCards UniProt Show fit	cAMP-dependent protein kinase inhibitor alpha
chr17_-_10549612 Show fit	7.16	ENST00000532183.6 ENST00000397183.6 ENST00000420805.1	MYH2 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 2
chr17_-_10549652 Show fit	6.81	ENST00000245503.10	MYH2 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 2
chr1_-_100178215 Show fit	6.59	ENST00000370138.1 ENST00000370137.6 ENST00000342895.7 ENST00000620882.4	LRRC39 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 39
chr2_+_167187364 Show fit	5.96	ENST00000672671.1	XIRP2 Ensembl NCBI GeneCards UniProt Show fit	xin actin binding repeat containing 2
chr11_-_13495984 Show fit	5.17	ENST00000282091.6	PTH Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone
chr11_-_13496018 Show fit	5.03	ENST00000529816.1	PTH Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone
chr17_-_10549694 Show fit	4.92	ENST00000622564.4	MYH2 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 2
chr3_-_42702638 Show fit	4.79	ENST00000417472.5 ENST00000442469.1	HHATL Ensembl NCBI GeneCards UniProt Show fit	hedgehog acyltransferase like
chr11_+_112175526 Show fit	4.57	ENST00000532612.5 ENST00000438022.5	BCO2 Ensembl NCBI GeneCards UniProt Show fit	beta-carotene oxygenase 2
chr1_+_207034366 Show fit	4.51	ENST00000545806.5 ENST00000618513.4	PFKFB2 Ensembl NCBI GeneCards UniProt Show fit	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr16_+_7332744 Show fit	4.44	ENST00000436368.6 ENST00000311745.9 ENST00000340209.8 ENST00000620507.4	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr11_+_112175501 Show fit	4.41	ENST00000357685.11 ENST00000361053.8	BCO2 Ensembl NCBI GeneCards UniProt Show fit	beta-carotene oxygenase 2
chr8_-_42501224 Show fit	4.38	ENST00000520262.6 ENST00000517366.1	SLC20A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 20 member 2
chr11_+_27041313 Show fit	3.89	ENST00000528583.5	BBOX1 Ensembl NCBI GeneCards UniProt Show fit	gamma-butyrobetaine hydroxylase 1
chr1_+_213987929 Show fit	3.58	ENST00000498508.6 ENST00000366958.9	PROX1 Ensembl NCBI GeneCards UniProt Show fit	prospero homeobox 1
chrM_+_5824 Show fit	3.48	ENST00000361624.2	MT-CO1 Ensembl NCBI GeneCards UniProt Show fit	mitochondrially encoded cytochrome c oxidase I
chr3_+_159839847 Show fit	3.44	ENST00000445224.6	SCHIP1 Ensembl NCBI GeneCards UniProt Show fit	schwannomin interacting protein 1
chr7_+_95485934 Show fit	2.98	ENST00000325885.6	ASB4 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and SOCS box containing 4
chr14_-_36519679 Show fit	2.98	ENST00000498187.6	NKX2-1 Ensembl NCBI GeneCards UniProt Show fit	NK2 homeobox 1
chr3_-_120682113 Show fit	2.90	ENST00000476082.2	HGD Ensembl NCBI GeneCards UniProt Show fit	homogentisate 1,2-dioxygenase
chr4_+_83536097 Show fit	2.89	ENST00000395226.6 ENST00000264409.5	GPAT3 Ensembl NCBI GeneCards UniProt Show fit	glycerol-3-phosphate acyltransferase 3
chr1_+_213988501 Show fit	2.79	ENST00000261454.8 ENST00000435016.2	PROX1 Ensembl NCBI GeneCards UniProt Show fit	prospero homeobox 1
chr15_-_101334157 Show fit	2.78	ENST00000632686.1	PCSK6 Ensembl NCBI GeneCards UniProt Show fit	proprotein convertase subtilisin/kexin type 6
chr2_-_68871382 Show fit	2.69	ENST00000295379.2	BMP10 Ensembl NCBI GeneCards UniProt Show fit	bone morphogenetic protein 10
chr14_-_80231052 Show fit	2.57	ENST00000557010.5	DIO2 Ensembl NCBI GeneCards UniProt Show fit	iodothyronine deiodinase 2
chr12_-_86256299 Show fit	2.51	ENST00000552808.6 ENST00000547225.5	MGAT4C Ensembl NCBI GeneCards UniProt Show fit	MGAT4 family member C
chr12_-_56643499 Show fit	2.50	ENST00000551570.5	ATP5F1B Ensembl NCBI GeneCards UniProt Show fit	ATP synthase F1 subunit beta
chr10_-_67696115 Show fit	2.42	ENST00000433211.7	CTNNA3 Ensembl NCBI GeneCards UniProt Show fit	catenin alpha 3
chr5_-_38557459 Show fit	2.31	ENST00000511561.1	LIFR Ensembl NCBI GeneCards UniProt Show fit	LIF receptor subunit alpha
chr7_-_13989658 Show fit	2.27	ENST00000430479.6 ENST00000433547.1 ENST00000405192.6	ETV1 Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 1
chr20_+_58888779 Show fit	2.27	ENST00000488546.6 ENST00000667293.2 ENST00000481039.6 ENST00000467321.6	GNAS Ensembl NCBI GeneCards UniProt Show fit	GNAS complex locus
chr16_+_7332839 Show fit	2.27	ENST00000355637.9	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr7_+_107470050 Show fit	2.26	ENST00000304402.6	GPR22 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 22
chr10_-_60572599 Show fit	2.18	ENST00000503366.5	ANK3 Ensembl NCBI GeneCards UniProt Show fit	ankyrin 3
chr20_+_58889100 Show fit	2.13	ENST00000477931.5 ENST00000485673.6	GNAS Ensembl NCBI GeneCards UniProt Show fit	GNAS complex locus
chrX_-_54998530 Show fit	2.12	ENST00000545676.5	PFKFB1 Ensembl NCBI GeneCards UniProt Show fit	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr20_+_58889143 Show fit	2.08	ENST00000470512.6 ENST00000464788.6 ENST00000469431.6 ENST00000478585.6 ENST00000604005.6	GNAS Ensembl NCBI GeneCards UniProt Show fit	GNAS complex locus
chr3_-_120682215 Show fit	2.07	ENST00000283871.10	HGD Ensembl NCBI GeneCards UniProt Show fit	homogentisate 1,2-dioxygenase
chr20_+_58889168 Show fit	2.03	ENST00000480975.5 ENST00000480232.6 ENST00000484504.5	GNAS Ensembl NCBI GeneCards UniProt Show fit	GNAS complex locus
chr11_-_16356538 Show fit	2.02	ENST00000683767.1	SOX6 Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 6
chr11_+_22666604 Show fit	2.01	ENST00000454584.6	GAS2 Ensembl NCBI GeneCards UniProt Show fit	growth arrest specific 2
chr12_-_86256267 Show fit	1.98	ENST00000620241.4	MGAT4C Ensembl NCBI GeneCards UniProt Show fit	MGAT4 family member C
chr16_+_6483379 Show fit	1.91	ENST00000552089.5	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr12_+_12785652 Show fit	1.88	ENST00000356591.5	APOLD1 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein L domain containing 1
chr1_-_216805367 Show fit	1.88	ENST00000360012.7	ESRRG Ensembl NCBI GeneCards UniProt Show fit	estrogen related receptor gamma
chr9_+_84669760 Show fit	1.85	ENST00000304053.10	NTRK2 Ensembl NCBI GeneCards UniProt Show fit	neurotrophic receptor tyrosine kinase 2
chr4_-_151226427 Show fit	1.83	ENST00000304527.8 ENST00000409598.8	SH3D19 Ensembl NCBI GeneCards UniProt Show fit	SH3 domain containing 19
chr2_-_190062721 Show fit	1.80	ENST00000260950.5	MSTN Ensembl NCBI GeneCards UniProt Show fit	myostatin
chr18_-_31162849 Show fit	1.76	ENST00000257197.7 ENST00000257198.6	DSC1 Ensembl NCBI GeneCards UniProt Show fit	desmocollin 1
chr9_+_84669707 Show fit	1.76	ENST00000277120.8 ENST00000323115.10	NTRK2 Ensembl NCBI GeneCards UniProt Show fit	neurotrophic receptor tyrosine kinase 2
chr12_-_86256376 Show fit	1.73	ENST00000552435.6	MGAT4C Ensembl NCBI GeneCards UniProt Show fit	MGAT4 family member C
chr20_+_54475584 Show fit	1.66	ENST00000262593.10	DOK5 Ensembl NCBI GeneCards UniProt Show fit	docking protein 5
chr2_+_100821025 Show fit	1.65	ENST00000427413.5	NPAS2 Ensembl NCBI GeneCards UniProt Show fit	neuronal PAS domain protein 2
chr10_-_119178791 Show fit	1.62	ENST00000298510.4	PRDX3 Ensembl NCBI GeneCards UniProt Show fit	peroxiredoxin 3
chr10_-_114632011 Show fit	1.61	ENST00000651023.1	ABLIM1 Ensembl NCBI GeneCards UniProt Show fit	actin binding LIM protein 1
chr12_+_111099423 Show fit	1.52	ENST00000397643.3	CUX2 Ensembl NCBI GeneCards UniProt Show fit	cut like homeobox 2
chr10_-_100065394 Show fit	1.51	ENST00000441382.1	CPN1 Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase N subunit 1
chr5_-_57482808 Show fit	1.50	ENST00000423391.3	ACTBL2 Ensembl NCBI GeneCards UniProt Show fit	actin beta like 2
chr9_-_113401249 Show fit	1.48	ENST00000409155.8 ENST00000448137.5	ALAD Ensembl NCBI GeneCards UniProt Show fit	aminolevulinate dehydratase
chr20_+_54475647 Show fit	1.45	ENST00000395939.5	DOK5 Ensembl NCBI GeneCards UniProt Show fit	docking protein 5
chr5_-_1882902 Show fit	1.43	ENST00000231357.7	IRX4 Ensembl NCBI GeneCards UniProt Show fit	iroquois homeobox 4
chr15_+_80059651 Show fit	1.34	ENST00000561012.5 ENST00000261749.11 ENST00000564367.5 ENST00000558494.5	ZFAND6 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 6
chr15_+_51377247 Show fit	1.33	ENST00000396399.6	GLDN Ensembl NCBI GeneCards UniProt Show fit	gliomedin
chr12_+_27524151 Show fit	1.27	ENST00000545334.5 ENST00000540114.5 ENST00000537927.5 ENST00000228425.11 ENST00000318304.12 ENST00000535047.5 ENST00000542629.5	PPFIBP1 Ensembl NCBI GeneCards UniProt Show fit	PPFIA binding protein 1
chr14_+_39265278 Show fit	1.23	ENST00000554392.5 ENST00000555716.5 ENST00000341749.7 ENST00000557038.5	MIA2 Ensembl NCBI GeneCards UniProt Show fit	MIA SH3 domain ER export factor 2
chr15_+_51377410 Show fit	1.23	ENST00000612989.1	GLDN Ensembl NCBI GeneCards UniProt Show fit	gliomedin
chr2_-_179562576 Show fit	1.23	ENST00000336917.9	ZNF385B Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 385B
chr1_+_155689074 Show fit	1.18	ENST00000343043.7 ENST00000421487.6 ENST00000535183.5 ENST00000368336.10 ENST00000465375.5 ENST00000470830.5	DAP3 Ensembl NCBI GeneCards UniProt Show fit	death associated protein 3
chr14_-_22926413 Show fit	1.16	ENST00000556043.5	PRMT5 Ensembl NCBI GeneCards UniProt Show fit	protein arginine methyltransferase 5
chr12_-_102950835 Show fit	1.14	ENST00000546844.1	PAH Ensembl NCBI GeneCards UniProt Show fit	phenylalanine hydroxylase
chr17_-_10469558 Show fit	1.14	ENST00000255381.2	MYH4 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 4
chr7_-_141014629 Show fit	1.12	ENST00000393008.7	MRPS33 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S33
chr7_-_13988863 Show fit	1.11	ENST00000405358.8	ETV1 Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 1
chr7_+_129375830 Show fit	1.10	ENST00000466993.5	AHCYL2 Ensembl NCBI GeneCards UniProt Show fit	adenosylhomocysteinase like 2
chr7_+_1232865 Show fit	1.10	ENST00000316333.9	UNCX Ensembl NCBI GeneCards UniProt Show fit	UNC homeobox
chr12_+_71664352 Show fit	1.05	ENST00000547843.1	THAP2 Ensembl NCBI GeneCards UniProt Show fit	THAP domain containing 2
chr1_+_170663134 Show fit	1.02	ENST00000367760.7	PRRX1 Ensembl NCBI GeneCards UniProt Show fit	paired related homeobox 1
chr7_+_8435187 Show fit	1.02	ENST00000429542.1	NXPH1 Ensembl NCBI GeneCards UniProt Show fit	neurexophilin 1
chr17_-_69141878 Show fit	0.98	ENST00000590645.1 ENST00000284425.7	ABCA6 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily A member 6
chr15_+_51377315 Show fit	0.98	ENST00000558426.5	GLDN Ensembl NCBI GeneCards UniProt Show fit	gliomedin
chr5_+_151026966 Show fit	0.97	ENST00000520059.1	GPX3 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 3
chr15_+_36702009 Show fit	0.96	ENST00000562489.1	CDIN1 Ensembl NCBI GeneCards UniProt Show fit	CDAN1 interacting nuclease 1
chr11_-_62545629 Show fit	0.94	ENST00000528508.5 ENST00000533365.5	AHNAK Ensembl NCBI GeneCards UniProt Show fit	AHNAK nucleoprotein
chr17_-_41382298 Show fit	0.94	ENST00000394001.3	KRT34 Ensembl NCBI GeneCards UniProt Show fit	keratin 34
chr3_+_9732480 Show fit	0.94	ENST00000426583.2	BRPF1 Ensembl NCBI GeneCards UniProt Show fit	bromodomain and PHD finger containing 1
chr6_-_31546716 Show fit	0.92	ENST00000483251.1	ATP6V1G2 Ensembl NCBI GeneCards UniProt Show fit	ATPase H+ transporting V1 subunit G2
chrX_+_11822423 Show fit	0.92	ENST00000656302.1 ENST00000640291.2	FRMPD4 Ensembl NCBI GeneCards UniProt Show fit	FERM and PDZ domain containing 4
chr3_-_115147237 Show fit	0.89	ENST00000357258.8	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr7_+_32957385 Show fit	0.88	ENST00000538336.5 ENST00000242209.9	FKBP9 Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 9
chr1_-_193106048 Show fit	0.86	ENST00000367440.3	GLRX2 Ensembl NCBI GeneCards UniProt Show fit	glutaredoxin 2
chr1_+_245154963 Show fit	0.86	ENST00000407071.7	KIF26B Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 26B
chr6_+_12716554 Show fit	0.82	ENST00000676159.1	PHACTR1 Ensembl NCBI GeneCards UniProt Show fit	phosphatase and actin regulator 1
chr3_-_115147277 Show fit	0.81	ENST00000675478.1	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr7_+_8435063 Show fit	0.81	ENST00000438764.1	NXPH1 Ensembl NCBI GeneCards UniProt Show fit	neurexophilin 1
chr1_-_159862648 Show fit	0.80	ENST00000368100.1	VSIG8 Ensembl NCBI GeneCards UniProt Show fit	V-set and immunoglobulin domain containing 8
chr9_+_122742303 Show fit	0.79	ENST00000304720.3	OR1L6 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 1 subfamily L member 6
chr5_-_59430600 Show fit	0.79	ENST00000636120.1	PDE4D Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 4D
chr16_+_67246895 Show fit	0.76	ENST00000566345.6	SLC9A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 9 member A5
chr5_-_1882744 Show fit	0.72	ENST00000511126.1	IRX4 Ensembl NCBI GeneCards UniProt Show fit	iroquois homeobox 4
chr15_+_80059568 Show fit	0.68	ENST00000613266.4 ENST00000561060.5	ZFAND6 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 6
chr12_-_23950906 Show fit	0.68	ENST00000541847.5	SOX5 Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 5
chr3_+_2511597 Show fit	0.67	ENST00000434053.5	CNTN4 Ensembl NCBI GeneCards UniProt Show fit	contactin 4
chr5_+_67004618 Show fit	0.67	ENST00000261569.11 ENST00000436277.5	MAST4 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated serine/threonine kinase family member 4
chr18_+_3247778 Show fit	0.67	ENST00000217652.8 ENST00000578611.5 ENST00000583449.1	MYL12A Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 12A
chr2_+_127646145 Show fit	0.67	ENST00000486700.2 ENST00000272644.7	GPR17 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 17
chr15_+_89088417 Show fit	0.66	ENST00000569550.5 ENST00000565066.5 ENST00000565973.5 ENST00000352732.10	ABHD2 Ensembl NCBI GeneCards UniProt Show fit	abhydrolase domain containing 2, acylglycerol lipase
chr1_+_167329148 Show fit	0.66	ENST00000420254.7	POU2F1 Ensembl NCBI GeneCards UniProt Show fit	POU class 2 homeobox 1
chr14_+_37595847 Show fit	0.65	ENST00000556845.1	TTC6 Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 6
chr10_-_104085793 Show fit	0.62	ENST00000650263.1	COL17A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XVII alpha 1 chain
chr12_-_10939263 Show fit	0.62	ENST00000537503.2	TAS2R14 Ensembl NCBI GeneCards UniProt Show fit	taste 2 receptor member 14
chr2_-_25794641 Show fit	0.61	ENST00000673455.1	ASXL2 Ensembl NCBI GeneCards UniProt Show fit	ASXL transcriptional regulator 2
chr5_-_124746630 Show fit	0.60	ENST00000513986.2	ZNF608 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 608
chr3_-_115071333 Show fit	0.60	ENST00000462705.5	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr11_-_59615673 Show fit	0.59	ENST00000263847.6	OSBP Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein
chr5_+_159916475 Show fit	0.58	ENST00000306675.5	ADRA1B Ensembl NCBI GeneCards UniProt Show fit	adrenoceptor alpha 1B
chr8_-_10655137 Show fit	0.58	ENST00000382483.4	RP1L1 Ensembl NCBI GeneCards UniProt Show fit	RP1 like 1
chr3_+_122384167 Show fit	0.58	ENST00000232125.9 ENST00000477892.5 ENST00000469967.1	FAM162A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 162 member A
chr10_+_116545907 Show fit	0.58	ENST00000369221.2	PNLIP Ensembl NCBI GeneCards UniProt Show fit	pancreatic lipase
chr10_-_104085762 Show fit	0.58	ENST00000393211.3	COL17A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XVII alpha 1 chain
chr5_+_55853464 Show fit	0.57	ENST00000652039.1	IL31RA Ensembl NCBI GeneCards UniProt Show fit	interleukin 31 receptor A
chr2_+_53767772 Show fit	0.56	ENST00000295304.5	CHAC2 Ensembl NCBI GeneCards UniProt Show fit	ChaC glutathione specific gamma-glutamylcyclotransferase 2
chr7_+_18290089 Show fit	0.55	ENST00000433709.6	HDAC9 Ensembl NCBI GeneCards UniProt Show fit	histone deacetylase 9
chr7_+_95485898 Show fit	0.54	ENST00000428113.5	ASB4 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and SOCS box containing 4
chr15_+_80059635 Show fit	0.53	ENST00000559157.5	ZFAND6 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 6
chr11_-_5059627 Show fit	0.53	ENST00000321522.2	OR52E2 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 52 subfamily E member 2
chr6_+_31546845 Show fit	0.53	ENST00000376146.8	NFKBIL1 Ensembl NCBI GeneCards UniProt Show fit	NFKB inhibitor like 1
chr18_+_13612614 Show fit	0.51	ENST00000586765.1 ENST00000677910.1	LDLRAD4 Ensembl NCBI GeneCards UniProt Show fit	low density lipoprotein receptor class A domain containing 4
chr7_+_129375643 Show fit	0.50	ENST00000490911.5	AHCYL2 Ensembl NCBI GeneCards UniProt Show fit	adenosylhomocysteinase like 2
chr14_-_20436161 Show fit	0.49	ENST00000636854.3	KLHL33 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 33
chr2_-_2324935 Show fit	0.47	ENST00000649709.1	MYT1L Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1 like
chr15_+_85544036 Show fit	0.47	ENST00000558166.2	AKAP13 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 13
chr2_-_2324642 Show fit	0.47	ENST00000650485.1 ENST00000649207.1	MYT1L Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1 like
chr6_-_55875583 Show fit	0.46	ENST00000370830.4	BMP5 Ensembl NCBI GeneCards UniProt Show fit	bone morphogenetic protein 5
chr19_+_33373694 Show fit	0.45	ENST00000284000.9	CEBPG Ensembl NCBI GeneCards UniProt Show fit	CCAAT enhancer binding protein gamma
chr11_+_124611420 Show fit	0.45	ENST00000284288.3	PANX3 Ensembl NCBI GeneCards UniProt Show fit	pannexin 3
chr2_-_2324968 Show fit	0.44	ENST00000649641.1	MYT1L Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1 like
chr17_-_10421944 Show fit	0.43	ENST00000403437.2	MYH8 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 8
chr1_-_151790475 Show fit	0.39	ENST00000368825.7 ENST00000368823.5 ENST00000368824.8 ENST00000458431.6 ENST00000368827.10 ENST00000440583.6	TDRKH Ensembl NCBI GeneCards UniProt Show fit	tudor and KH domain containing
chr12_-_10807286 Show fit	0.39	ENST00000240615.3	TAS2R8 Ensembl NCBI GeneCards UniProt Show fit	taste 2 receptor member 8
chr11_+_124183219 Show fit	0.38	ENST00000641351.2	OR10D3 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 10 subfamily D member 3
chr5_+_68290637 Show fit	0.38	ENST00000336483.9	PIK3R1 Ensembl NCBI GeneCards UniProt Show fit	phosphoinositide-3-kinase regulatory subunit 1
chr1_-_151346846 Show fit	0.38	ENST00000436271.5 ENST00000450506.5 ENST00000422595.5	RFX5 Ensembl NCBI GeneCards UniProt Show fit	regulatory factor X5
chr6_-_116829037 Show fit	0.37	ENST00000368549.7 ENST00000530250.1 ENST00000310357.8	GPRC6A Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor class C group 6 member A
chr1_+_158461574 Show fit	0.35	ENST00000641432.1 ENST00000641460.1 ENST00000641535.1 ENST00000641971.1	OR10K1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 10 subfamily K member 1
chr13_-_83882390 Show fit	0.35	ENST00000377084.3	SLITRK1 Ensembl NCBI GeneCards UniProt Show fit	SLIT and NTRK like family member 1
chr1_+_167329044 Show fit	0.34	ENST00000367862.9	POU2F1 Ensembl NCBI GeneCards UniProt Show fit	POU class 2 homeobox 1
chr11_+_121101243 Show fit	0.34	ENST00000392793.6 ENST00000642222.1	TECTA Ensembl NCBI GeneCards UniProt Show fit	tectorin alpha
chr11_+_5351508 Show fit	0.33	ENST00000380219.1	OR51B6 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 51 subfamily B member 6
chr10_-_49396074 Show fit	0.32	ENST00000374139.8	DRGX Ensembl NCBI GeneCards UniProt Show fit	dorsal root ganglia homeobox
chr4_+_87832917 Show fit	0.32	ENST00000395102.8 ENST00000497649.6 ENST00000540395.1 ENST00000560249.5 ENST00000511670.5 ENST00000361056.3	MEPE Ensembl NCBI GeneCards UniProt Show fit	matrix extracellular phosphoglycoprotein
chr4_-_152352800 Show fit	0.29	ENST00000393956.9	FBXW7 Ensembl NCBI GeneCards UniProt Show fit	F-box and WD repeat domain containing 7
chr13_-_52848632 Show fit	0.29	ENST00000377942.7 ENST00000338862.5	PCDH8 Ensembl NCBI GeneCards UniProt Show fit	protocadherin 8
chr6_+_69233023 Show fit	0.27	ENST00000604969.1 ENST00000603207.1	ADGRB3 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor B3
chr14_+_36661852 Show fit	0.25	ENST00000361487.7	PAX9 Ensembl NCBI GeneCards UniProt Show fit	paired box 9
chr7_-_13986498 Show fit	0.25	ENST00000420159.6 ENST00000399357.7 ENST00000403527.5	ETV1 Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 1
chr5_+_153491174 Show fit	0.25	ENST00000521843.6	GRIA1 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 1
chr7_-_29195186 Show fit	0.23	ENST00000449801.5 ENST00000409850.5	CPVL Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase vitellogenic like
chr8_-_94436926 Show fit	0.20	ENST00000481490.3	FSBP Ensembl NCBI GeneCards UniProt Show fit	fibrinogen silencer binding protein
chrX_+_41688967 Show fit	0.19	ENST00000378142.9	GPR34 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 34
chr14_-_21159060 Show fit	0.17	ENST00000641039.1 ENST00000641697.1	OR5AU1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 5 subfamily AU member 1
chr10_-_33334382 Show fit	0.16	ENST00000374823.9 ENST00000374821.9 ENST00000374816.7	NRP1 Ensembl NCBI GeneCards UniProt Show fit	neuropilin 1
chr6_+_12716760 Show fit	0.16	ENST00000332995.12	PHACTR1 Ensembl NCBI GeneCards UniProt Show fit	phosphatase and actin regulator 1
chr7_+_18290416 Show fit	0.15	ENST00000413509.6	HDAC9 Ensembl NCBI GeneCards UniProt Show fit	histone deacetylase 9
chr2_-_2324323 Show fit	0.15	ENST00000648339.1 ENST00000647694.1	MYT1L Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1 like
chr3_-_62374293 Show fit	0.14	ENST00000486811.5	FEZF2 Ensembl NCBI GeneCards UniProt Show fit	FEZ family zinc finger 2
chr6_+_121437378 Show fit	0.14	ENST00000650427.1 ENST00000647564.1	GJA1 Ensembl NCBI GeneCards UniProt Show fit	gap junction protein alpha 1
chr8_+_76681208 Show fit	0.13	ENST00000651372.2	ZFHX4 Ensembl NCBI GeneCards UniProt Show fit	zinc finger homeobox 4
chr7_-_75611702 Show fit	0.13	ENST00000616821.4 ENST00000420909.1	HIP1 Ensembl NCBI GeneCards UniProt Show fit	huntingtin interacting protein 1
chr12_-_23951020 Show fit	0.13	ENST00000441133.2 ENST00000545921.5	SOX5 Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 5
chr8_-_28490220 Show fit	0.10	ENST00000517673.5 ENST00000380254.7 ENST00000518734.5 ENST00000346498.6	FBXO16 Ensembl NCBI GeneCards UniProt Show fit	F-box protein 16
chr2_-_210476687 Show fit	0.10	ENST00000233714.8 ENST00000443314.5 ENST00000441020.7 ENST00000450366.7 ENST00000431941.6	LANCL1 Ensembl NCBI GeneCards UniProt Show fit	LanC like 1
chr12_-_57051173 Show fit	0.07	ENST00000433964.5	MYO1A Ensembl NCBI GeneCards UniProt Show fit	myosin IA
chr14_+_45135917 Show fit	0.07	ENST00000267430.10 ENST00000556036.5 ENST00000542564.6	FANCM Ensembl NCBI GeneCards UniProt Show fit	FA complementation group M
chr5_-_88883701 Show fit	0.07	ENST00000636998.1	MEF2C Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2C
chr5_+_66958870 Show fit	0.05	ENST00000405643.5 ENST00000407621.1 ENST00000432426.5	MAST4 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated serine/threonine kinase family member 4
chrX_+_41689006 Show fit	0.04	ENST00000378138.5 ENST00000620846.1 ENST00000649219.1	GPR34 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 34
chr5_-_146182591 Show fit	0.04	ENST00000510191.5 ENST00000674277.1 ENST00000674447.1 ENST00000674270.1 ENST00000394434.7 ENST00000674290.1 ENST00000674398.1 ENST00000674174.1	LARS1 Ensembl NCBI GeneCards UniProt Show fit	leucyl-tRNA synthetase 1
chr5_-_146182475 Show fit	0.03	ENST00000674158.1 ENST00000674191.1 ENST00000274562.13	LARS1 Ensembl NCBI GeneCards UniProt Show fit	leucyl-tRNA synthetase 1
chr7_+_141719162 Show fit	0.03	ENST00000493845.1	WEE2 Ensembl NCBI GeneCards UniProt Show fit	WEE2 oocyte meiosis inhibiting kinase
chr19_-_1021114 Show fit	0.03	ENST00000333175.9 ENST00000356663.8	TMEM259 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 259
chrX_-_111410420 Show fit	0.03	ENST00000371993.7 ENST00000680476.1	DCX Ensembl NCBI GeneCards UniProt Show fit	doublecortin
chr1_-_41918858 Show fit	0.02	ENST00000372583.6	HIVEP3 Ensembl NCBI GeneCards UniProt Show fit	HIVEP zinc finger 3
chr14_+_22501542 Show fit	0.02	ENST00000390498.1	TRAJ39 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha joining 39
chr6_+_50818701 Show fit	0.02	ENST00000344788.7	TFAP2B Ensembl NCBI GeneCards UniProt Show fit	transcription factor AP-2 beta
chr12_-_23944301 Show fit	0.01	ENST00000538083.1	SOX5 Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 5
chr5_+_153490727 Show fit	0.01	ENST00000340592.9	GRIA1 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 1
chr12_-_119803383 Show fit	0.01	ENST00000392520.2 ENST00000678677.1 ENST00000679249.1 ENST00000676849.1	CIT Ensembl NCBI GeneCards UniProt Show fit	citron rho-interacting serine/threonine kinase

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA4

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.1	12.5	GO:0060262	regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
3.0	9.0	GO:0016121	tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
2.2	8.9	GO:0032972	diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
2.1	6.4	GO:0043049	hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
2.0	10.2	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
1.2	3.6	GO:0099540	synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
1.0	8.4	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
1.0	18.9	GO:0001778	plasma membrane repair(GO:0001778)
0.9	6.6	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.7	2.2	GO:0048561	establishment of organ orientation(GO:0048561)
0.7	2.7	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.6	8.8	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.5	8.5	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.5	5.0	GO:0006572	tyrosine catabolic process(GO:0006572)
0.5	1.5	GO:0070541	response to platinum ion(GO:0070541)
0.5	2.8	GO:0032902	nerve growth factor production(GO:0032902)
0.4	12.5	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.4	1.6	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.4	2.3	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.4	1.8	GO:1902725	negative regulation of satellite cell differentiation(GO:1902725)
0.3	7.4	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3	3.0	GO:0021759	globus pallidus development(GO:0021759)
0.3	1.5	GO:0030070	insulin processing(GO:0030070)
0.3	3.9	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.3	2.0	GO:0021778	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.3	2.2	GO:0072660	maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2	4.4	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.2	2.4	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2	1.6	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.2	3.5	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.2	3.5	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.2	0.5	GO:0071676	negative regulation of mononuclear cell migration(GO:0071676)
0.1	3.6	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1	1.2	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1	1.0	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.1	2.6	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	3.1	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1	3.5	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1	0.6	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1	1.1	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
0.1	2.5	GO:0051775	response to redox state(GO:0051775)
0.1	0.9	GO:0072092	ureteric bud invasion(GO:0072092)
0.1	2.9	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1	1.2	GO:0048664	neuron fate determination(GO:0048664)
0.1	1.1	GO:1902221	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	8.6	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.9	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.1	0.3	GO:2000639	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1	0.8	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1	2.6	GO:0006625	protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1	0.8	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1	1.9	GO:0042118	endothelial cell activation(GO:0042118)
0.1	1.5	GO:0007614	short-term memory(GO:0007614)
0.1	0.5	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1	6.0	GO:0055008	cardiac muscle tissue morphogenesis(GO:0055008)
0.1	0.5	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	4.7	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.0	0.1	GO:2000588	positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0	0.2	GO:0061552	vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0	0.8	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.3	GO:0099558	maintenance of synapse structure(GO:0099558)
0.0	2.3	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.6	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0010652	regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0	0.6	GO:0061365	positive regulation of triglyceride lipase activity(GO:0061365)
0.0	0.7	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	1.6	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	1.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.4	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.6	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.6	GO:0006751	glutathione catabolic process(GO:0006751)
0.0	1.0	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.5	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.5	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.5	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0	0.9	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	0.4	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	2.3	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.3	GO:0021559	trigeminal nerve development(GO:0021559)
0.0	0.6	GO:0044126	regulation of growth of symbiont in host(GO:0044126)
0.0	9.6	GO:0000209	protein polyubiquitination(GO:0000209)
0.0	0.7	GO:0007413	axonal fasciculation(GO:0007413)
0.0	1.5	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.6	GO:0048240	sperm capacitation(GO:0048240)
0.0	9.2	GO:0006936	muscle contraction(GO:0006936)
0.0	0.4	GO:0051531	NFAT protein import into nucleus(GO:0051531)
0.0	0.6	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0	0.3	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.0	GO:0035038	female pronucleus assembly(GO:0035038)
0.0	0.6	GO:0045494	photoreceptor cell maintenance(GO:0045494)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	18.9	GO:0005826	actomyosin contractile ring(GO:0005826)
1.5	8.9	GO:1990584	cardiac Troponin complex(GO:1990584)
1.5	8.8	GO:0014802	terminal cisterna(GO:0014802)
0.4	18.5	GO:0005859	muscle myosin complex(GO:0005859)
0.4	8.5	GO:0016461	unconventional myosin complex(GO:0016461)
0.3	3.5	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2	3.5	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2	2.6	GO:0005916	fascia adherens(GO:0005916)
0.1	8.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	31.6	GO:0031674	I band(GO:0031674)
0.1	1.6	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	1.2	GO:0034709	methylosome(GO:0034709)
0.1	0.4	GO:0071547	piP-body(GO:0071547)
0.1	2.3	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	0.7	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	0.9	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	2.2	GO:0005921	gap junction(GO:0005921)
0.0	1.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.9	GO:0043034	costamere(GO:0043034)
0.0	0.4	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0	1.5	GO:0005839	proteasome core complex(GO:0005839)
0.0	1.2	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.3	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0	3.6	GO:0043195	terminal bouton(GO:0043195)
0.0	2.8	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0071821	FANCM-MHF complex(GO:0071821)
0.0	0.2	GO:0097443	sorting endosome(GO:0097443)
0.0	5.5	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.3	GO:0043083	synaptic cleft(GO:0043083)
0.0	9.8	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	0.6	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.7	GO:0016459	myosin complex(GO:0016459)
0.0	0.3	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.2	12.5	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.7	5.0	GO:0004411	homogentisate 1,2-dioxygenase activity(GO:0004411)
1.2	3.6	GO:0060175	brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
1.0	3.9	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.9	8.9	GO:0031013	troponin I binding(GO:0031013)
0.8	6.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.7	6.6	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.6	11.1	GO:0031433	telethonin binding(GO:0031433)
0.6	2.3	GO:0004923	leukemia inhibitory factor receptor activity(GO:0004923)
0.5	1.5	GO:1904854	proteasome core complex binding(GO:1904854)
0.5	6.4	GO:0050692	DBD domain binding(GO:0050692)
0.5	4.4	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.4	2.9	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.4	20.5	GO:0000146	microfilament motor activity(GO:0000146)
0.4	2.6	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.3	18.5	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.2	2.4	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2	7.4	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2	1.6	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2	3.5	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2	9.0	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2	1.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.2	1.9	GO:0050682	AF-2 domain binding(GO:0050682)
0.2	1.6	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.2	2.8	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.6	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	1.2	GO:0044020	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1	3.0	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1	0.9	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.1	0.6	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
0.1	0.9	GO:0030613	oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1	3.5	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	18.0	GO:0003774	motor activity(GO:0003774)
0.1	0.4	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.1	6.0	GO:0051393	alpha-actinin binding(GO:0051393)
0.1	0.9	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	0.3	GO:0050816	phosphothreonine binding(GO:0050816)
0.1	1.0	GO:0008430	selenium binding(GO:0008430)
0.1	0.3	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.1	1.4	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	3.5	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.8	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.8	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.0	1.0	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.6	GO:0008142	oxysterol binding(GO:0008142)
0.0	15.7	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	0.6	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.7	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	2.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	2.6	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	1.7	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.5	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.7	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	6.1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.6	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.2	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.5	GO:0008301	DNA binding, bending(GO:0008301)
0.0	1.0	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.7	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	0.7	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.6	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	1.2	GO:0002039	p53 binding(GO:0002039)
0.0	2.3	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	4.3	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	1.0	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	18.9	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	3.6	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	1.7	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	3.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	3.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	1.2	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.3	PID MYC PATHWAY	C-MYC pathway
0.0	1.0	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	1.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	1.4	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.5	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	1.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	1.2	PID P53 REGULATION PATHWAY	p53 pathway
0.0	1.6	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.2	8.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	9.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	2.6	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	10.0	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.1	6.6	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	2.8	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	13.4	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	1.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	2.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.0	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	1.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	10.0	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.6	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	5.1	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	1.0	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	1.8	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	4.1	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.4	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	3.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.6	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.6	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation

Results for HOXA4

Z-value: 2.03

Motif logo

Transcription factors associated with HOXA4

Activity-expression correlation:

Activity profile of HOXA4 motif

Sorted Z-values of HOXA4 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: