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Illumina Body Map 2 (GSE30611)

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Results for HOXB3

Z-value: 1.03

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Transcription factors associated with HOXB3

Gene Symbol Gene ID Gene Info
HOXB3
ENSG00000120093.12 homeobox B3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB3hg38_v1_chr17_-_48590231_485902580.522.0e-03Click!

Activity profile of HOXB3 motif

Sorted Z-values of HOXB3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_88885397 6.05 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr14_-_106038355 4.54 ENST00000390597.3
IGHV2-5
immunoglobulin heavy variable 2-5
chr22_+_22811737 4.44 ENST00000390315.3
IGLV3-10
immunoglobulin lambda variable 3-10
chr2_-_88861563 4.32 ENST00000624935.3
ENST00000390241.3
ENSG00000240040.6
IGKJ2
novel transcript
immunoglobulin kappa joining 2
chr22_+_22720615 4.19 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr2_-_89177160 4.07 ENST00000484817.1
IGKV2-24
immunoglobulin kappa variable 2-24
chr4_-_25863537 4.00 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L3
SEL1L family member 3
chr14_-_106470788 3.65 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr2_+_90038848 3.10 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr22_+_22375984 2.97 ENST00000390296.2
IGLV5-45
immunoglobulin lambda variable 5-45
chr16_+_11965193 2.65 ENST00000053243.6
ENST00000396495.3
TNFRSF17
TNF receptor superfamily member 17
chr19_+_17527250 2.59 ENST00000599164.6
ENST00000449408.6
ENST00000600871.5
ENST00000599124.1
NIBAN3
niban apoptosis regulator 3
chr4_+_40196907 2.53 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
RHOH
ras homolog family member H
chr2_+_90004792 2.43 ENST00000462693.1
IGKV2D-24
immunoglobulin kappa variable 2D-24 (non-functional)
chr12_-_122716790 2.35 ENST00000528880.3
HCAR3
hydroxycarboxylic acid receptor 3
chr8_-_48921735 2.10 ENST00000396822.6
SNAI2
snail family transcriptional repressor 2
chr8_-_48921419 1.87 ENST00000020945.4
SNAI2
snail family transcriptional repressor 2
chr7_+_2519763 1.85 ENST00000222725.10
ENST00000359574.7
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_-_122703346 1.81 ENST00000328880.6
HCAR2
hydroxycarboxylic acid receptor 2
chr3_+_114294020 1.77 ENST00000383671.8
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr14_+_20781139 1.69 ENST00000304677.3
RNASE6
ribonuclease A family member k6
chr11_-_107858777 1.66 ENST00000525815.6
SLC35F2
solute carrier family 35 member F2
chrX_+_136648214 1.65 ENST00000370628.2
CD40LG
CD40 ligand
chrX_+_136648138 1.65 ENST00000370629.7
CD40LG
CD40 ligand
chr2_-_88861920 1.63 ENST00000390242.2
IGKJ1
immunoglobulin kappa joining 1
chr6_+_29550407 1.55 ENST00000641137.1
OR2I1P
olfactory receptor family 2 subfamily I member 1 pseudogene
chr15_-_55270383 1.54 ENST00000396307.6
RAB27A
RAB27A, member RAS oncogene family
chr21_-_14546297 1.52 ENST00000400566.6
ENST00000400564.5
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr7_+_100119607 1.51 ENST00000262932.5
CNPY4
canopy FGF signaling regulator 4
chr15_-_55270280 1.42 ENST00000564609.5
RAB27A
RAB27A, member RAS oncogene family
chr11_+_5691004 1.41 ENST00000414641.5
TRIM22
tripartite motif containing 22
chr8_+_91249307 1.41 ENST00000309536.6
ENST00000276609.8
SLC26A7
solute carrier family 26 member 7
chr4_+_40197023 1.40 ENST00000381799.10
RHOH
ras homolog family member H
chr11_-_105035113 1.38 ENST00000526568.5
ENST00000531166.5
ENST00000534497.5
ENST00000527979.5
ENST00000533400.6
ENST00000528974.1
ENST00000525825.5
ENST00000353247.9
ENST00000446369.5
ENST00000436863.7
CASP1
caspase 1
chr15_-_55270874 1.36 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A
RAB27A, member RAS oncogene family
chr19_-_5286163 1.33 ENST00000592099.5
ENST00000588012.5
ENST00000262963.10
ENST00000587303.5
ENST00000590509.5
PTPRS
protein tyrosine phosphatase receptor type S
chr19_+_49513353 1.33 ENST00000596975.5
FCGRT
Fc fragment of IgG receptor and transporter
chr14_+_100019375 1.32 ENST00000544450.6
EVL
Enah/Vasp-like
chr16_+_11965234 1.29 ENST00000562385.1
TNFRSF17
TNF receptor superfamily member 17
chr14_+_21997531 1.26 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr19_+_1077394 1.25 ENST00000590577.2
ARHGAP45
Rho GTPase activating protein 45
chr3_-_151329539 1.24 ENST00000325602.6
P2RY13
purinergic receptor P2Y13
chr14_+_22096017 1.20 ENST00000390452.2
TRDV1
T cell receptor delta variable 1
chr16_+_22513523 1.16 ENST00000538606.5
ENST00000451409.5
ENST00000424340.5
ENST00000517539.5
ENST00000528249.5
NPIPB5
nuclear pore complex interacting protein family member B5
chr1_-_201171545 1.16 ENST00000367333.6
TMEM9
transmembrane protein 9
chr19_+_17527232 1.15 ENST00000601861.5
NIBAN3
niban apoptosis regulator 3
chr19_+_49487510 1.13 ENST00000679106.1
ENST00000621674.4
ENST00000391857.9
ENST00000678510.1
ENST00000467825.2
RPL13A
ribosomal protein L13a
chr6_+_130018565 1.12 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL3
L3MBTL histone methyl-lysine binding protein 3
chr12_-_14938508 1.11 ENST00000266397.7
ERP27
endoplasmic reticulum protein 27
chr21_+_42403874 1.11 ENST00000319294.11
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr7_+_142300924 1.09 ENST00000455382.2
TRBV2
T cell receptor beta variable 2
chr16_-_29505820 1.08 ENST00000550665.5
NPIPB12
nuclear pore complex interacting protein family member B12
chr8_+_27311471 1.08 ENST00000397501.5
PTK2B
protein tyrosine kinase 2 beta
chr3_+_122055355 1.07 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86
CD86 molecule
chr16_+_22513058 1.04 ENST00000536620.1
NPIPB5
nuclear pore complex interacting protein family member B5
chr16_-_21425278 1.02 ENST00000504841.6
ENST00000419180.6
NPIPB3
nuclear pore complex interacting protein family member B3
chr12_-_7936177 1.02 ENST00000544291.1
ENST00000075120.12
SLC2A3
solute carrier family 2 member 3
chr12_-_15662692 1.01 ENST00000540613.5
EPS8
epidermal growth factor receptor pathway substrate 8
chrX_+_15749848 1.01 ENST00000479740.5
ENST00000454127.2
CA5B
carbonic anhydrase 5B
chr12_+_56128217 1.00 ENST00000267113.4
ENST00000394048.10
ESYT1
extended synaptotagmin 1
chr5_-_50441350 0.98 ENST00000508934.5
EMB
embigin
chr7_-_55552741 0.97 ENST00000418904.5
VOPP1
VOPP1 WW domain binding protein
chr13_+_101489940 0.96 ENST00000376162.7
ITGBL1
integrin subunit beta like 1
chr1_+_222737283 0.93 ENST00000360827.6
FAM177B
family with sequence similarity 177 member B
chr14_+_61187544 0.91 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
PRKCH
protein kinase C eta
chr7_+_26291850 0.90 ENST00000338523.9
ENST00000446848.6
SNX10
sorting nexin 10
chr14_+_21852457 0.89 ENST00000390435.1
TRAV8-3
T cell receptor alpha variable 8-3
chr16_-_21857418 0.89 ENST00000415645.6
NPIPB4
nuclear pore complex interacting protein family member B4
chr16_-_29404029 0.88 ENST00000524087.5
NPIPB11
nuclear pore complex interacting protein family member B11
chr2_-_88861258 0.88 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr17_-_64130813 0.87 ENST00000606895.2
ERN1
endoplasmic reticulum to nucleus signaling 1
chr16_-_21857657 0.87 ENST00000341400.11
ENST00000518761.8
ENST00000682606.1
NPIPB4
nuclear pore complex interacting protein family member B4
chr11_-_107858561 0.86 ENST00000375682.8
SLC35F2
solute carrier family 35 member F2
chr11_+_121576760 0.85 ENST00000532694.5
ENST00000534286.5
SORL1
sortilin related receptor 1
chr19_-_3557563 0.85 ENST00000389395.7
ENST00000355415.7
MFSD12
major facilitator superfamily domain containing 12
chr6_-_25042003 0.84 ENST00000510784.8
RIPOR2
RHO family interacting cell polarization regulator 2
chr9_-_122828539 0.84 ENST00000259467.9
PDCL
phosducin like
chr3_-_131026726 0.84 ENST00000514044.5
ENST00000264992.8
ASTE1
asteroid homolog 1
chr11_+_5689691 0.84 ENST00000425490.5
TRIM22
tripartite motif containing 22
chr6_-_75119058 0.83 ENST00000493109.2
COL12A1
collagen type XII alpha 1 chain
chr4_+_173168800 0.83 ENST00000512285.5
ENST00000265000.9
GALNT7
polypeptide N-acetylgalactosaminyltransferase 7
chr1_+_222737196 0.82 ENST00000434700.5
FAM177B
family with sequence similarity 177 member B
chr2_-_101308681 0.82 ENST00000295317.4
RNF149
ring finger protein 149
chr1_+_159008978 0.81 ENST00000447473.6
IFI16
interferon gamma inducible protein 16
chr1_+_78649818 0.81 ENST00000370747.9
ENST00000438486.1
IFI44
interferon induced protein 44
chr11_-_60183011 0.79 ENST00000533023.5
ENST00000420732.6
ENST00000528851.6
MS4A6A
membrane spanning 4-domains A6A
chr11_-_96343170 0.79 ENST00000524717.6
MAML2
mastermind like transcriptional coactivator 2
chr2_+_137964446 0.75 ENST00000280096.5
ENST00000280097.5
HNMT
histamine N-methyltransferase
chr4_-_137532452 0.75 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
PCDH18
protocadherin 18
chr9_+_12775012 0.74 ENST00000319264.4
LURAP1L
leucine rich adaptor protein 1 like
chr5_-_160119389 0.73 ENST00000523662.1
ENST00000456329.7
ENST00000307063.9
PWWP2A
PWWP domain containing 2A
chr16_+_31873772 0.73 ENST00000394846.7
ENST00000300870.15
ZNF267
zinc finger protein 267
chr9_+_122371036 0.72 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
PTGS1
prostaglandin-endoperoxide synthase 1
chr1_-_92486916 0.72 ENST00000294702.6
GFI1
growth factor independent 1 transcriptional repressor
chr17_+_32021005 0.71 ENST00000327564.11
ENST00000584368.5
ENST00000394713.7
ENST00000341671.11
LRRC37B
leucine rich repeat containing 37B
chr13_+_30906706 0.71 ENST00000428944.1
MEDAG
mesenteric estrogen dependent adipogenesis
chr11_-_60183191 0.70 ENST00000412309.6
MS4A6A
membrane spanning 4-domains A6A
chr3_-_131026558 0.70 ENST00000504725.1
ENST00000509060.1
ASTE1
asteroid homolog 1
chr17_-_46579651 0.70 ENST00000573185.5
ENST00000570550.5
ENST00000445552.6
ENST00000329240.10
ENST00000622488.6
ENST00000336125.6
ARL17A
ADP ribosylation factor like GTPase 17A
chr22_-_32255344 0.69 ENST00000266086.6
SLC5A4
solute carrier family 5 member 4
chr1_+_161721563 0.69 ENST00000367948.6
FCRLB
Fc receptor like B
chr9_+_122371014 0.69 ENST00000362012.7
PTGS1
prostaglandin-endoperoxide synthase 1
chr5_-_34043205 0.69 ENST00000382065.8
ENST00000231338.7
C1QTNF3
C1q and TNF related 3
chr17_-_8867639 0.67 ENST00000619866.5
PIK3R6
phosphoinositide-3-kinase regulatory subunit 6
chr2_+_142877653 0.67 ENST00000375773.6
ENST00000409512.5
ENST00000264170.9
ENST00000410015.6
KYNU
kynureninase
chr6_+_36594354 0.66 ENST00000373715.11
SRSF3
serine and arginine rich splicing factor 3
chr5_+_149357999 0.65 ENST00000274569.9
PCYOX1L
prenylcysteine oxidase 1 like
chr15_-_55270249 0.65 ENST00000568803.1
RAB27A
RAB27A, member RAS oncogene family
chr17_-_46361718 0.63 ENST00000575960.5
ENST00000575698.5
ENST00000571246.5
ENST00000434041.6
ENST00000656849.1
ENST00000570618.5
ENST00000450673.4
ENST00000622877.4
ARL17B
ADP ribosylation factor like GTPase 17B
chr11_-_125111708 0.63 ENST00000531909.5
ENST00000529530.1
TMEM218
transmembrane protein 218
chr11_-_118212885 0.61 ENST00000524477.5
JAML
junction adhesion molecule like
chr11_-_95789744 0.61 ENST00000358780.10
ENST00000542135.5
FAM76B
family with sequence similarity 76 member B
chr19_+_54137740 0.61 ENST00000644245.1
ENST00000646002.1
ENST00000221232.11
ENST00000440571.6
ENST00000617930.2
CNOT3
CCR4-NOT transcription complex subunit 3
chr1_+_167721954 0.60 ENST00000359523.7
ENST00000392121.7
ENST00000474859.5
MPZL1
myelin protein zero like 1
chr7_+_26291898 0.60 ENST00000416246.5
SNX10
sorting nexin 10
chr1_+_27934980 0.59 ENST00000373894.8
SMPDL3B
sphingomyelin phosphodiesterase acid like 3B
chr7_-_101217569 0.59 ENST00000223127.8
PLOD3
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
chr4_-_142846275 0.59 ENST00000513000.5
ENST00000509777.5
ENST00000503927.5
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr6_-_32128191 0.59 ENST00000453203.2
ENST00000375203.8
ENST00000375201.8
ATF6B
activating transcription factor 6 beta
chr17_-_75262344 0.58 ENST00000579743.2
ENST00000578348.5
ENST00000582486.5
ENST00000582717.5
GGA3
golgi associated, gamma adaptin ear containing, ARF binding protein 3
chr3_-_143848442 0.58 ENST00000474151.1
ENST00000316549.11
SLC9A9
solute carrier family 9 member A9
chr1_-_1778790 0.58 ENST00000341991.7
NADK
NAD kinase
chr5_+_140639419 0.57 ENST00000513002.5
ENST00000394671.8
TMCO6
transmembrane and coiled-coil domains 6
chr4_-_163613505 0.57 ENST00000339875.9
MARCHF1
membrane associated ring-CH-type finger 1
chr15_+_40765620 0.57 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr12_-_76423256 0.57 ENST00000546946.5
OSBPL8
oxysterol binding protein like 8
chr4_+_25160631 0.56 ENST00000510415.1
ENST00000507794.2
ENST00000512921.4
SEPSECS-AS1
PI4K2B
SEPSECS antisense RNA 1 (head to head)
phosphatidylinositol 4-kinase type 2 beta
chr15_-_44676824 0.56 ENST00000560110.1
PATL2
PAT1 homolog 2
chr9_+_122370523 0.56 ENST00000643810.1
ENST00000540753.6
PTGS1
prostaglandin-endoperoxide synthase 1
chr8_+_97869040 0.55 ENST00000254898.7
ENST00000524308.5
ENST00000522025.6
MATN2
matrilin 2
chr13_+_45464901 0.55 ENST00000349995.10
COG3
component of oligomeric golgi complex 3
chr19_+_49527988 0.55 ENST00000270645.8
RCN3
reticulocalbin 3
chrX_+_41689006 0.55 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
GPR34
G protein-coupled receptor 34
chr8_-_121641424 0.53 ENST00000303924.5
HAS2
hyaluronan synthase 2
chr6_-_116545658 0.53 ENST00000368602.4
TRAPPC3L
trafficking protein particle complex 3 like
chr18_+_63887698 0.53 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
SERPINB2
serpin family B member 2
chr2_+_8682046 0.52 ENST00000331129.3
ENST00000396290.2
ID2
inhibitor of DNA binding 2
chr2_+_171453122 0.52 ENST00000611110.4
ENST00000339506.7
DCAF17
DDB1 and CUL4 associated factor 17
chr11_+_33039996 0.52 ENST00000432887.5
ENST00000528898.1
ENST00000531632.6
TCP11L1
t-complex 11 like 1
chr16_+_14186707 0.52 ENST00000572567.5
MRTFB
myocardin related transcription factor B
chr12_+_15546344 0.51 ENST00000674388.1
ENST00000542557.5
ENST00000445537.6
ENST00000544244.5
ENST00000442921.7
PTPRO
protein tyrosine phosphatase receptor type O
chr20_-_290717 0.51 ENST00000360321.7
ENST00000400269.4
C20orf96
chromosome 20 open reading frame 96
chr17_-_50707855 0.51 ENST00000285243.7
ANKRD40
ankyrin repeat domain 40
chr5_+_132873660 0.51 ENST00000296877.3
LEAP2
liver enriched antimicrobial peptide 2
chr7_-_100119323 0.50 ENST00000523306.5
ENST00000344095.8
ENST00000417349.5
ENST00000493322.5
ENST00000520135.5
ENST00000460673.2
ENST00000453269.7
ENST00000452041.5
ENST00000452438.6
ENST00000451699.5
TAF6
TATA-box binding protein associated factor 6
chr17_+_46295099 0.50 ENST00000393465.7
ENST00000320254.5
LRRC37A
leucine rich repeat containing 37A
chr17_-_35119733 0.50 ENST00000460118.6
ENST00000335858.11
RAD51D
RAD51 paralog D
chr11_+_47272244 0.49 ENST00000422579.1
MADD
MAP kinase activating death domain
chr1_+_160400543 0.49 ENST00000368061.3
VANGL2
VANGL planar cell polarity protein 2
chr5_+_172641241 0.49 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr3_-_52535006 0.48 ENST00000307076.8
NT5DC2
5'-nucleotidase domain containing 2
chr15_+_64387828 0.47 ENST00000261884.8
TRIP4
thyroid hormone receptor interactor 4
chr2_+_48314637 0.46 ENST00000413569.5
ENST00000340553.8
FOXN2
forkhead box N2
chr6_+_26204552 0.46 ENST00000615164.2
H4C5
H4 clustered histone 5
chr1_-_1778399 0.45 ENST00000341426.9
NADK
NAD kinase
chrX_+_41688967 0.45 ENST00000378142.9
GPR34
G protein-coupled receptor 34
chr11_-_95789474 0.44 ENST00000536839.1
FAM76B
family with sequence similarity 76 member B
chr12_+_16347102 0.43 ENST00000536371.5
ENST00000010404.6
MGST1
microsomal glutathione S-transferase 1
chr6_-_110815152 0.43 ENST00000413605.6
CDK19
cyclin dependent kinase 19
chr11_+_95790459 0.43 ENST00000325486.9
ENST00000325542.10
ENST00000544522.5
ENST00000541365.5
CEP57
centrosomal protein 57
chr12_-_51028234 0.42 ENST00000547688.7
ENST00000394904.9
SLC11A2
solute carrier family 11 member 2
chr22_+_21642287 0.42 ENST00000248958.5
SDF2L1
stromal cell derived factor 2 like 1
chr3_+_158801926 0.42 ENST00000622669.4
ENST00000392813.8
ENST00000415822.8
ENST00000651862.1
ENST00000264266.12
MFSD1
major facilitator superfamily domain containing 1
chr14_-_24242600 0.42 ENST00000646753.1
ENST00000558566.1
ENST00000267415.12
ENST00000559019.1
ENST00000399423.8
ENST00000626689.2
TINF2
TERF1 interacting nuclear factor 2
chr8_+_27311620 0.41 ENST00000522338.5
PTK2B
protein tyrosine kinase 2 beta
chr20_-_45972171 0.41 ENST00000322927.3
ZNF335
zinc finger protein 335
chr16_+_51553436 0.41 ENST00000565308.2
HNRNPA1P48
heterogeneous nuclear ribonucleoprotein A1 pseudogene 48
chr20_+_59996335 0.41 ENST00000244049.7
ENST00000350849.10
ENST00000456106.1
CDH26
cadherin 26
chr4_+_85604146 0.40 ENST00000512201.5
ARHGAP24
Rho GTPase activating protein 24
chr1_-_150697128 0.40 ENST00000427665.1
ENST00000271732.8
GOLPH3L
golgi phosphoprotein 3 like
chr4_+_94207596 0.40 ENST00000359052.8
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr3_-_122022122 0.40 ENST00000393631.5
ENST00000273691.7
ENST00000344209.10
ILDR1
immunoglobulin like domain containing receptor 1
chr11_-_60243103 0.39 ENST00000651255.1
MS4A4E
membrane spanning 4-domains A4E
chrX_+_13689116 0.39 ENST00000464506.2
ENST00000243325.6
RAB9A
RAB9A, member RAS oncogene family
chr3_+_136819069 0.38 ENST00000393079.3
ENST00000446465.3
SLC35G2
solute carrier family 35 member G2
chr5_+_140639494 0.38 ENST00000252100.6
TMCO6
transmembrane and coiled-coil domains 6
chr19_+_48445961 0.38 ENST00000253237.10
GRWD1
glutamate rich WD repeat containing 1
chr12_+_16347665 0.37 ENST00000535309.5
ENST00000540056.5
ENST00000396209.5
ENST00000540126.5
MGST1
microsomal glutathione S-transferase 1
chr12_+_16347637 0.37 ENST00000543076.5
ENST00000396210.8
MGST1
microsomal glutathione S-transferase 1
chr1_+_15764419 0.36 ENST00000441801.6
FBLIM1
filamin binding LIM protein 1
chr1_+_192636121 0.36 ENST00000543215.5
ENST00000391995.7
RGS13
regulator of G protein signaling 13
chr2_+_186694007 0.35 ENST00000304698.10
FAM171B
family with sequence similarity 171 member B
chr4_-_99290975 0.35 ENST00000209668.3
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr8_-_41309434 0.35 ENST00000220772.8
SFRP1
secreted frizzled related protein 1
chr6_-_169250825 0.35 ENST00000676869.1
ENST00000676760.1
THBS2
thrombospondin 2
chr10_+_4963406 0.34 ENST00000380872.9
ENST00000442997.5
AKR1C1
aldo-keto reductase family 1 member C1
chrX_-_13817027 0.34 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
GPM6B
glycoprotein M6B
chr12_+_54854505 0.34 ENST00000308796.11
ENST00000619042.1
MUCL1
mucin like 1
chr12_-_6631632 0.34 ENST00000431922.1
LPAR5
lysophosphatidic acid receptor 5
chr7_-_135211313 0.34 ENST00000682802.1
ENST00000683848.1
ENST00000354475.5
WDR91
WD repeat domain 91
chr8_+_56211686 0.33 ENST00000521831.5
ENST00000303759.3
ENST00000517636.5
ENST00000517933.5
ENST00000355315.8
ENST00000518801.5
ENST00000523975.5
ENST00000396723.9
ENST00000523061.5
ENST00000521524.5
CHCHD7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr19_+_49528290 0.33 ENST00000597801.1
RCN3
reticulocalbin 3
chr7_-_100167284 0.33 ENST00000413800.5
GAL3ST4
galactose-3-O-sulfotransferase 4
chr8_-_673547 0.33 ENST00000522893.1
ERICH1
glutamate rich 1
chr7_-_100119840 0.32 ENST00000437822.6
TAF6
TATA-box binding protein associated factor 6
chr4_+_127632926 0.31 ENST00000335251.11
INTU
inturned planar cell polarity protein
chr22_-_28712136 0.31 ENST00000464581.6
CHEK2
checkpoint kinase 2
chr7_+_5879827 0.31 ENST00000416608.5
OCM
oncomodulin
chr6_-_110815408 0.30 ENST00000368911.8
CDK19
cyclin dependent kinase 19
chr19_+_48445795 0.30 ENST00000598711.1
GRWD1
glutamate rich WD repeat containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.7 5.0 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.5 1.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.4 1.3 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.4 1.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.4 1.8 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.4 1.1 GO:0002912 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.3 1.8 GO:0007386 compartment pattern specification(GO:0007386)
0.3 0.9 GO:1990579 protein trans-autophosphorylation(GO:0036290) peptidyl-serine trans-autophosphorylation(GO:1990579)
0.3 0.8 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 1.5 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2 0.7 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.2 0.7 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 1.3 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.2 0.7 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 1.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.2 0.6 GO:0031104 dendrite regeneration(GO:0031104)
0.2 0.8 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 1.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.9 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.6 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.1 0.8 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 0.5 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 3.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.5 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.1 1.0 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 21.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.5 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.6 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.3 GO:0014034 neural crest cell fate commitment(GO:0014034) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.9 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 1.0 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 2.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 1.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.3 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.9 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 0.5 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 2.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.4 GO:0019532 oxalate transport(GO:0019532)
0.1 1.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.4 GO:0015692 lead ion transport(GO:0015692)
0.1 0.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.7 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.1 0.6 GO:0035696 monocyte extravasation(GO:0035696)
0.1 13.9 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.8 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 0.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.2 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) negative regulation of mitotic cell cycle DNA replication(GO:1903464) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.6 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:0035419 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.3 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.3 GO:0010813 neuropeptide catabolic process(GO:0010813) substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 3.9 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 1.5 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.2 GO:0071874 microglia differentiation(GO:0014004) microglia development(GO:0014005) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.0 3.4 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0099404 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.0 0.4 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.7 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 1.1 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 1.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.6 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.3 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.2 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.5 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 2.0 GO:0070206 protein trimerization(GO:0070206)
0.0 0.1 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.7 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.8 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.5 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0 0.3 GO:0042730 fibrinolysis(GO:0042730)
0.0 1.2 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1990332 Ire1 complex(GO:1990332)
0.3 5.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 1.4 GO:0097179 protease inhibitor complex(GO:0097179)
0.2 0.7 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 0.8 GO:0005595 collagen type XII trimer(GO:0005595)
0.2 0.5 GO:0060187 cell pole(GO:0060187)
0.1 1.1 GO:0097452 GAIT complex(GO:0097452)
0.1 1.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 2.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.8 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 3.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.9 GO:0070187 telosome(GO:0070187)
0.1 1.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 3.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 1.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.0 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.0 2.2 GO:0015030 Cajal body(GO:0015030)
0.0 1.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 2.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 1.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.4 2.0 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.4 1.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 1.3 GO:0019770 IgG receptor activity(GO:0019770)
0.3 1.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 1.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.2 5.0 GO:0031489 myosin V binding(GO:0031489)
0.1 0.6 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.7 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.5 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.4 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 32.9 GO:0003823 antigen binding(GO:0003823)
0.1 3.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.6 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 1.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.3 GO:0047718 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.1 0.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 1.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.6 GO:0050700 CARD domain binding(GO:0050700)
0.1 2.0 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.7 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.4 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 1.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.2 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.1 1.2 GO:0043295 glutathione binding(GO:0043295)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 0.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.3 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.9 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.0 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 4.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.5 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 1.1 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.6 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.0 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 3.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 3.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 4.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds