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Illumina Body Map 2 (GSE30611)
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Results for HOXB7
Z-value: 0.98
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Transcription factors associated with HOXB7
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXB7 | hg38_v1_chr17_-_48610971_48611023 | -0.01 | 9.7e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXB7
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 7.6 | GO:0052696 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.0 | 6.9 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.3 | 6.0 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.3 | 4.9 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.0 | 4.2 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.5 | 3.3 | GO:0046092 | deoxycytidine metabolic process(GO:0046092) |
| 0.1 | 3.3 | GO:0048681 | negative regulation of axon regeneration(GO:0048681) |
| 0.0 | 3.2 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.4 | 2.8 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.2 | 2.8 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.6 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.2 | 6.6 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.2 | 5.1 | GO:0032982 | myosin filament(GO:0032982) |
| 0.1 | 3.2 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 3.0 | GO:0043034 | costamere(GO:0043034) |
| 0.1 | 2.9 | GO:0031045 | dense core granule(GO:0031045) |
| 0.0 | 2.9 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 2.8 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.4 | 2.7 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.1 | 2.7 | GO:0010369 | chromocenter(GO:0010369) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.2 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.2 | 8.1 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 6.9 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 5.1 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.2 | 4.3 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.0 | 4.3 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.1 | 4.1 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.5 | 3.8 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.4 | 3.3 | GO:0004797 | deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797) |
| 0.2 | 3.0 | GO:1990459 | transferrin receptor binding(GO:1990459) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.9 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 3.5 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.8 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 1.4 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 1.4 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.1 | 1.3 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 1.1 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.9 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.0 | 0.9 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 0.9 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 8.9 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.1 | 7.8 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 5.8 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 5.8 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 4.6 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.1 | 3.9 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 3.7 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.1 | 3.6 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.1 | 3.3 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 3.1 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |