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Illumina Body Map 2 (GSE30611)

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Results for HOXC13

Z-value: 0.76

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Transcription factors associated with HOXC13

Gene Symbol Gene ID Gene Info
ENSG00000123364.5 homeobox C13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC13hg38_v1_chr12_+_53938824_539388520.212.5e-01Click!

Activity profile of HOXC13 motif

Sorted Z-values of HOXC13 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_70666961 5.49 ENST00000510437.5
joining chain of multimeric IgA and IgM
chr4_-_70666884 3.36 ENST00000510614.5
joining chain of multimeric IgA and IgM
chr10_-_46046264 2.80 ENST00000581478.5
ENST00000582163.3
microseminoprotein beta
chr6_+_87407965 2.36 ENST00000369562.9
cilia and flagella associated protein 206
chr8_-_85378105 2.25 ENST00000521846.5
ENST00000523022.6
ENST00000524324.5
ENST00000519991.5
ENST00000520663.5
ENST00000517590.5
ENST00000522579.5
ENST00000522814.5
ENST00000522662.5
ENST00000523858.5
ENST00000519129.5
carbonic anhydrase 1
chr3_-_149377637 2.24 ENST00000305366.8
transmembrane 4 L six family member 1
chr4_-_154612635 1.97 ENST00000407946.5
ENST00000405164.5
ENST00000336098.8
ENST00000393846.6
ENST00000404648.7
ENST00000443553.5
fibrinogen gamma chain
chr1_+_192575765 1.76 ENST00000469578.2
ENST00000367459.8
regulator of G protein signaling 1
chr7_-_16833411 1.67 ENST00000412973.1
anterior gradient 2, protein disulphide isomerase family member
chr6_-_52803807 1.65 ENST00000334575.6
glutathione S-transferase alpha 1
chr18_-_63644250 1.64 ENST00000341074.10
ENST00000436264.1
serpin family B member 4
chr6_-_49713564 1.59 ENST00000616725.4
ENST00000618917.4
cysteine rich secretory protein 2
chr7_-_41703062 1.56 ENST00000242208.5
inhibin subunit beta A
chr8_-_27992663 1.56 ENST00000380385.6
ENST00000354914.8
scavenger receptor class A member 5
chr6_-_49713521 1.47 ENST00000339139.5
cysteine rich secretory protein 2
chr3_-_123620496 1.46 ENST00000578202.1
myosin light chain kinase
chr22_+_22758698 1.45 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr4_+_20251896 1.39 ENST00000504154.6
slit guidance ligand 2
chr2_-_189179754 1.38 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr12_-_91146195 1.37 ENST00000548218.1
decorin
chr14_-_106335613 1.36 ENST00000603660.1
immunoglobulin heavy variable 3-30
chr6_+_127577168 1.33 ENST00000329722.8
chromosome 6 open reading frame 58
chr6_-_52763473 1.33 ENST00000493422.3
glutathione S-transferase alpha 2
chr3_-_172523460 1.33 ENST00000420541.6
TNF superfamily member 10
chr1_-_109113818 1.32 ENST00000369949.8
chromosome 1 open reading frame 194
chr3_-_123620571 1.31 ENST00000583087.5
myosin light chain kinase
chr2_+_33134620 1.29 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr3_-_172523423 1.28 ENST00000241261.7
TNF superfamily member 10
chr1_-_209802149 1.20 ENST00000456314.1
interferon regulatory factor 6
chr4_+_168711416 1.18 ENST00000649826.1
palladin, cytoskeletal associated protein
chr14_-_106507476 1.17 ENST00000390621.3
immunoglobulin heavy variable 1-45
chr9_-_92404690 1.17 ENST00000447356.1
osteoglycin
chr2_+_33134579 1.16 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr17_-_76643748 1.10 ENST00000156626.12
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr9_-_92482499 1.04 ENST00000375544.7
asporin
chr15_+_70936487 1.04 ENST00000558456.5
ENST00000560158.6
ENST00000558808.5
ENST00000559806.5
ENST00000559069.1
leucine rich repeat containing 49
chr8_-_94262308 1.04 ENST00000297596.3
ENST00000396194.6
GTP binding protein overexpressed in skeletal muscle
chr3_+_130581741 1.03 ENST00000511332.1
collagen type VI alpha 6 chain
chr18_-_27143024 1.00 ENST00000581714.5
carbohydrate sulfotransferase 9
chr22_+_22322452 0.99 ENST00000390290.3
immunoglobulin lambda variable 1-51
chr1_+_43300971 0.99 ENST00000372476.8
ENST00000538015.1
tyrosine kinase with immunoglobulin like and EGF like domains 1
chr7_+_134866831 0.90 ENST00000435928.1
caldesmon 1
chr9_-_92482350 0.90 ENST00000375543.2
asporin
chr8_-_27992624 0.88 ENST00000524352.5
scavenger receptor class A member 5
chr9_+_110125491 0.88 ENST00000259318.7
PALM2 and AKAP2 fusion
chr1_+_109114097 0.88 ENST00000457623.6
ENST00000369939.8
ENST00000529753.5
endosome-lysosome associated apoptosis and autophagy regulator 1
chr3_+_111911604 0.86 ENST00000495180.1
pleckstrin homology like domain family B member 2
chr3_-_100993409 0.84 ENST00000471714.6
ABI family member 3 binding protein
chr12_-_91153149 0.78 ENST00000550758.1
decorin
chr12_-_114403898 0.78 ENST00000526441.1
T-box transcription factor 5
chr20_-_45791865 0.78 ENST00000243938.9
WAP four-disulfide core domain 3
chr2_+_102337148 0.77 ENST00000311734.6
ENST00000409584.5
interleukin 1 receptor like 1
chr20_+_38317627 0.76 ENST00000417318.3
bactericidal permeability increasing protein
chr5_-_180649579 0.74 ENST00000261937.11
ENST00000502649.5
fms related receptor tyrosine kinase 4
chr15_+_57599411 0.74 ENST00000569089.1
myocardial zonula adherens protein
chr1_-_169711603 0.74 ENST00000236147.6
ENST00000650983.1
selectin L
chr2_+_106063234 0.73 ENST00000409944.5
ECRG4 augurin precursor
chr2_+_191245185 0.73 ENST00000418908.5
ENST00000339514.8
ENST00000392318.8
myosin IB
chr11_+_118304721 0.72 ENST00000361763.9
CD3e molecule
chr15_+_70892443 0.72 ENST00000443425.6
ENST00000560369.5
leucine rich repeat containing 49
chr9_+_98943705 0.71 ENST00000610452.1
collagen type XV alpha 1 chain
chr3_-_99850976 0.69 ENST00000487087.5
filamin A interacting protein 1 like
chr1_+_174875505 0.69 ENST00000486220.5
RAB GTPase activating protein 1 like
chr6_-_117425905 0.68 ENST00000368507.8
ROS proto-oncogene 1, receptor tyrosine kinase
chr12_+_47079586 0.67 ENST00000432328.2
ENST00000546455.6
PC-esterase domain containing 1B
chr9_-_92482461 0.65 ENST00000651738.1
asporin
chr1_-_155910881 0.65 ENST00000609492.1
ENST00000368322.7
Ras like without CAAX 1
chr3_-_51875597 0.65 ENST00000446461.2
IQ motif containing F5
chr1_-_89126066 0.64 ENST00000370466.4
guanylate binding protein 2
chr5_+_42756811 0.64 ENST00000388827.4
ENST00000361970.10
coiled-coil domain containing 152
chr10_-_20897288 0.62 ENST00000377122.9
nebulette
chr19_+_53866139 0.60 ENST00000421337.6
ENST00000651087.1
myeloid associated differentiation marker
chr12_-_52814106 0.60 ENST00000551956.2
keratin 4
chr19_-_18522051 0.59 ENST00000262809.9
elongation factor for RNA polymerase II
chr6_+_87472925 0.59 ENST00000369556.7
ENST00000369557.9
ENST00000369552.9
solute carrier family 35 member A1
chr1_-_178869272 0.59 ENST00000444255.1
angiopoietin like 1
chr7_+_23710203 0.58 ENST00000422637.5
ENST00000355870.8
serine/threonine kinase 31
chr14_-_91867529 0.57 ENST00000435962.7
tandem C2 domains, nuclear
chr6_-_144008118 0.57 ENST00000629195.2
ENST00000650125.1
ENST00000647880.1
ENST00000649307.1
ENST00000674357.1
ENST00000417959.4
ENST00000635591.1
PLAG1 like zinc finger 1
hydatidiform mole associated and imprinted
chr4_-_174283614 0.57 ENST00000513696.1
ENST00000393674.7
ENST00000503293.5
F-box protein 8
chr2_+_137964446 0.56 ENST00000280096.5
ENST00000280097.5
histamine N-methyltransferase
chr15_-_58279245 0.54 ENST00000558231.5
aldehyde dehydrogenase 1 family member A2
chr7_+_23710326 0.54 ENST00000354639.7
ENST00000531170.5
ENST00000444333.2
serine/threonine kinase 31
chr14_+_49598910 0.54 ENST00000298288.11
leucine rich repeat protein 1
chr18_+_63887698 0.54 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr6_+_30489501 0.53 ENST00000376630.5
major histocompatibility complex, class I, E
chr6_-_46954922 0.53 ENST00000265417.7
adhesion G protein-coupled receptor F5
chr3_-_160399207 0.52 ENST00000465537.5
ENST00000486856.5
ENST00000468218.5
ENST00000478370.5
ENST00000326448.12
intraflagellar transport 80
chr5_+_111073309 0.52 ENST00000379706.4
thymic stromal lymphopoietin
chr11_+_101914997 0.52 ENST00000263468.13
centrosomal protein 126
chr6_+_33272067 0.51 ENST00000474973.5
ENST00000439602.7
ribosomal protein S18
chr6_+_42155399 0.50 ENST00000623004.2
ENST00000372963.4
ENST00000654459.1
GUCA1A neighbor
guanylate cyclase activator 1A
chr1_-_149861210 0.50 ENST00000579512.2
H4 clustered histone 15
chr7_-_29112894 0.50 ENST00000448959.5
carboxypeptidase vitellogenic like
chr1_+_173635332 0.49 ENST00000417563.3
testis expressed 50
chr3_-_160399247 0.49 ENST00000489004.5
ENST00000496589.5
intraflagellar transport 80
chr9_-_127771335 0.49 ENST00000373276.7
ENST00000373277.8
SH2 domain containing 3C
chr10_+_50990864 0.49 ENST00000401604.8
protein kinase cGMP-dependent 1
chr6_-_73523757 0.49 ENST00000455918.2
ENST00000677236.1
eukaryotic translation elongation factor 1 alpha 1
chr3_+_50173807 0.49 ENST00000420831.1
semaphorin 3F
chr7_+_23710263 0.49 ENST00000433467.6
serine/threonine kinase 31
chr17_+_50373214 0.48 ENST00000393271.6
ENST00000338165.9
ENST00000511519.6
essential meiotic structure-specific endonuclease 1
chr9_-_128656649 0.48 ENST00000372715.7
dynein 2 intermediate chain 2
chr2_+_33134406 0.48 ENST00000432635.1
latent transforming growth factor beta binding protein 1
chr16_-_67999468 0.48 ENST00000393847.6
ENST00000573808.1
ENST00000572624.5
dipeptidase 2
chr11_+_102112445 0.48 ENST00000524575.5
Yes1 associated transcriptional regulator
chr6_-_36547400 0.47 ENST00000229812.8
serine/threonine kinase 38
chr19_+_8842593 0.47 ENST00000305625.2
methyl-CpG binding domain protein 3 like 1
chr6_-_32371872 0.47 ENST00000527965.5
ENST00000532023.5
ENST00000447241.6
ENST00000534588.1
testis expressed basic protein 1
chr4_-_163473732 0.46 ENST00000280605.5
transketolase like 2
chr15_-_99249523 0.46 ENST00000560235.1
ENST00000394132.7
ENST00000560860.5
ENST00000558078.5
ENST00000560772.5
tetratricopeptide repeat domain 23
chr6_+_133953210 0.45 ENST00000367869.1
ENST00000237264.9
ENST00000674115.1
TATA-box binding protein like 1
novel protein
chr5_-_180649613 0.45 ENST00000393347.7
ENST00000619105.4
fms related receptor tyrosine kinase 4
chr4_+_89901979 0.45 ENST00000508372.1
multimerin 1
chr13_-_102798958 0.45 ENST00000376004.5
protein O-glucosyltransferase 2
chr11_+_85855377 0.44 ENST00000342404.8
coiled-coil domain containing 83
chr12_-_9208388 0.44 ENST00000261336.7
PZP alpha-2-macroglobulin like
chr14_-_67412112 0.44 ENST00000216446.9
pleckstrin 2
chr6_-_32371897 0.44 ENST00000442822.6
ENST00000375015.8
ENST00000533191.5
testis expressed basic protein 1
chr3_+_57890011 0.43 ENST00000494088.6
ENST00000438794.5
sarcolemma associated protein
chr10_+_100997040 0.42 ENST00000370223.7
leucine zipper tumor suppressor 2
chr9_-_2844058 0.42 ENST00000397885.3
pumilio RNA binding family member 3
chr3_+_42936354 0.40 ENST00000383748.9
KRAB box domain containing 1
chr1_+_54641806 0.39 ENST00000409996.5
maestro heat like repeat family member 7
chr17_-_76643648 0.39 ENST00000589992.1
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr19_+_44905785 0.39 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
apolipoprotein E
chr1_+_54641754 0.38 ENST00000339553.9
ENST00000421030.7
maestro heat like repeat family member 7
chr1_+_206406377 0.38 ENST00000605476.5
SLIT-ROBO Rho GTPase activating protein 2
chr1_+_158845798 0.37 ENST00000438394.1
myeloid cell nuclear differentiation antigen
chr1_-_46176482 0.36 ENST00000540385.2
ENST00000506599.2
P3R3URF-PIK3R3 readthrough
PIK3R3 upstream reading frame
chr1_+_159009886 0.36 ENST00000340979.10
ENST00000368131.8
ENST00000295809.12
ENST00000368132.7
interferon gamma inducible protein 16
chr12_-_57237090 0.36 ENST00000556732.1
NDUFA4 mitochondrial complex associated like 2
chr12_-_54295748 0.35 ENST00000540264.2
ENST00000312156.8
nuclear factor, erythroid 2
chr12_-_13095628 0.35 ENST00000457134.6
ENST00000537302.5
germ cell associated 1
chr6_-_75243770 0.35 ENST00000472311.6
ENST00000460985.1
ENST00000377978.3
ENST00000684430.1
ENST00000509698.6
cytochrome c oxidase subunit 7A2
chr12_+_96489569 0.35 ENST00000524981.9
cilia and flagella associated protein 54
chr19_+_16888991 0.34 ENST00000248076.4
F2R like thrombin or trypsin receptor 3
chr1_+_39215255 0.33 ENST00000671089.1
microtubule actin crosslinking factor 1
chr19_-_6737565 0.33 ENST00000601716.1
ENST00000264080.11
G protein-coupled receptor 108
chr20_+_38962299 0.33 ENST00000373325.6
ENST00000373323.8
ENST00000252011.8
ENST00000615559.1
DEAH-box helicase 35
novel transcript, sense intronic to DHX35
chr5_+_35852695 0.33 ENST00000508941.5
interleukin 7 receptor
chr1_-_79188467 0.33 ENST00000656300.1
adhesion G protein-coupled receptor L4
chr19_-_35228699 0.32 ENST00000324675.3
family with sequence similarity 187 member B
chr1_+_149832647 0.32 ENST00000578186.2
H4 clustered histone 14
chr4_-_185471082 0.32 ENST00000507501.5
ENST00000506962.3
coiled-coil domain containing 110
chr16_-_11273610 0.31 ENST00000327157.4
protamine 3
chr17_-_58692032 0.31 ENST00000349033.10
ENST00000389934.7
testis expressed 14, intercellular bridge forming factor
chr4_+_69995958 0.31 ENST00000381060.2
ENST00000246895.9
statherin
chr7_-_25180278 0.31 ENST00000283905.8
ENST00000409280.5
ENST00000415598.5
chromosome 7 open reading frame 31
chr7_+_23680130 0.30 ENST00000409192.7
ENST00000409653.5
ENST00000409994.3
ENST00000344962.9
family with sequence similarity 221 member A
chr14_+_96256194 0.30 ENST00000216629.11
ENST00000553356.1
bradykinin receptor B1
chr3_-_108953870 0.29 ENST00000261047.8
guanylate cyclase activator 1C
chr19_+_3762665 0.29 ENST00000330133.5
mitochondrial ribosomal protein L54
chr3_-_108953762 0.29 ENST00000393963.7
ENST00000471108.1
guanylate cyclase activator 1C
chr22_+_32043253 0.29 ENST00000266088.9
solute carrier family 5 member 1
chr10_+_30434602 0.29 ENST00000413724.5
mitogen-activated protein kinase kinase kinase 8
chr17_-_8383164 0.29 ENST00000584164.6
ENST00000582556.5
ENST00000648839.1
ENST00000578812.5
ENST00000583011.6
ribosomal protein L26
chr2_+_161136901 0.28 ENST00000259075.6
ENST00000432002.5
TRAF family member associated NFKB activator
chr22_+_39520747 0.28 ENST00000676430.1
activating transcription factor 4
chr2_+_102418642 0.28 ENST00000264260.6
interleukin 18 receptor accessory protein
chr7_-_93148345 0.28 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chrX_+_56729231 0.28 ENST00000637096.1
ENST00000374922.9
ENST00000423617.2
negative regulator of P-body association
chr22_-_39532722 0.28 ENST00000334678.8
ribosomal protein S19 binding protein 1
chr4_-_1208825 0.27 ENST00000511679.5
ENST00000617421.4
spondin 2
chr21_+_38256698 0.26 ENST00000613499.4
ENST00000612702.4
ENST00000398925.5
ENST00000398928.5
ENST00000328656.8
ENST00000443341.5
potassium inwardly rectifying channel subfamily J member 15
chr9_+_121121760 0.25 ENST00000373847.5
centriolin
chr1_+_54641816 0.25 ENST00000395690.6
maestro heat like repeat family member 7
chr7_+_23710236 0.25 ENST00000456014.6
serine/threonine kinase 31
chr6_-_32371912 0.25 ENST00000612031.4
testis expressed basic protein 1
chr6_-_32816910 0.25 ENST00000447394.1
ENST00000438763.7
major histocompatibility complex, class II, DO beta
chr3_+_129440196 0.25 ENST00000507564.5
ENST00000348417.7
ENST00000504021.5
ENST00000349441.6
intraflagellar transport 122
chr13_+_33818122 0.24 ENST00000380071.8
replication factor C subunit 3
chr2_+_161160420 0.24 ENST00000392749.7
ENST00000405852.5
TRAF family member associated NFKB activator
chrX_+_13689171 0.24 ENST00000618931.2
RAB9A, member RAS oncogene family
chr11_-_114559866 0.24 ENST00000534921.2
neurexophilin and PC-esterase domain family member 1
chr16_+_11965193 0.24 ENST00000053243.6
ENST00000396495.3
TNF receptor superfamily member 17
chr4_-_149815826 0.22 ENST00000636793.2
ENST00000636414.1
IQ motif containing M
chr3_+_178419123 0.21 ENST00000614557.1
ENST00000455307.5
ENST00000436432.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript)
long intergenic non-protein coding RNA 1014
chr10_-_77637902 0.21 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
potassium calcium-activated channel subfamily M alpha 1
chr22_+_39520553 0.21 ENST00000674920.3
ENST00000679776.1
ENST00000675582.2
ENST00000337304.2
ENST00000676346.2
ENST00000396680.3
ENST00000680446.1
ENST00000674568.2
ENST00000680748.1
ENST00000674835.2
activating transcription factor 4
chr6_+_133953156 0.20 ENST00000367871.5
TATA-box binding protein like 1
chr11_-_114559847 0.19 ENST00000251921.6
neurexophilin and PC-esterase domain family member 1
chr3_-_179451387 0.19 ENST00000675901.1
ENST00000232564.8
ENST00000674862.1
ENST00000497513.1
G protein subunit beta 4
chr12_-_15662692 0.19 ENST00000540613.5
epidermal growth factor receptor pathway substrate 8
chr5_+_150640652 0.19 ENST00000307662.5
synaptopodin
chr17_-_58692021 0.19 ENST00000240361.12
testis expressed 14, intercellular bridge forming factor
chr22_-_37844308 0.18 ENST00000411961.6
ENST00000434930.1
ENST00000215941.9
ankyrin repeat domain 54
chrX_+_13689116 0.18 ENST00000464506.2
ENST00000243325.6
RAB9A, member RAS oncogene family
chr21_+_46286623 0.18 ENST00000397691.1
ybeY metalloendoribonuclease
chr9_-_34329205 0.18 ENST00000684219.1
ENST00000402558.7
kinesin family member 24
chr4_+_53377749 0.18 ENST00000507166.5
novel FIP1L1-PDGFRA fusion protein
chr19_-_56393430 0.18 ENST00000589895.1
ENST00000589143.5
ENST00000301310.8
ENST00000586929.5
zinc finger protein 582
chr9_-_72060605 0.18 ENST00000377024.8
ENST00000651200.2
ENST00000652752.1
chromosome 9 open reading frame 57
chr6_+_144330797 0.17 ENST00000628146.2
utrophin
chr6_+_43130583 0.16 ENST00000481946.5
protein tyrosine kinase 7 (inactive)
chr19_-_8698705 0.16 ENST00000612068.1
actin like 9
chr6_+_150721073 0.16 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chr6_-_11807045 0.15 ENST00000379415.6
androgen dependent TFPI regulating protein
chr12_+_92702983 0.15 ENST00000344636.6
ENST00000544406.2
pleckstrin homology and RhoGEF domain containing G7
chr7_-_86965872 0.15 ENST00000398276.6
ENST00000416314.5
ENST00000425689.1
endosome-lysosome associated apoptosis and autophagy regulator family member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 8.9 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.7 2.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.5 1.6 GO:0060279 positive regulation of ovulation(GO:0060279)
0.5 1.4 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.3 1.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 1.7 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.3 2.9 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 2.6 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.3 2.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 0.8 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.3 1.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.8 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.7 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.4 GO:0010877 lipid transport involved in lipid storage(GO:0010877) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
0.1 0.5 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.5 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.7 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 2.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.7 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 2.6 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 0.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 3.0 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 0.6 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 1.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 2.5 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 0.4 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.3 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.1 2.4 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.2 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 0.7 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 1.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 1.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.1 1.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.4 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.1 0.2 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.3 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.5 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.0 0.5 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.0 0.3 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.6 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 1.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.4 GO:0052405 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 2.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.4 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 2.7 GO:0003341 cilium movement(GO:0003341)
0.0 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.5 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 1.2 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 4.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.5 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.0 1.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.3 GO:0046541 saliva secretion(GO:0046541)
0.0 0.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.5 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0045355 negative regulation of interferon-alpha biosynthetic process(GO:0045355) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.0 1.7 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.5 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.4 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.9 GO:0071757 hexameric IgM immunoglobulin complex(GO:0071757)
0.8 2.4 GO:0001534 radial spoke(GO:0001534)
0.5 1.6 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 1.4 GO:0005588 collagen type V trimer(GO:0005588)
0.2 2.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.5 GO:1990617 CHOP-ATF4 complex(GO:1990617)
0.2 2.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.6 GO:0035363 histone locus body(GO:0035363)
0.1 2.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.5 GO:0071148 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.1 0.2 GO:0097444 spine apparatus(GO:0097444)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.7 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.7 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.1 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 2.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 1.0 GO:0051233 spindle midzone(GO:0051233)
0.0 1.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0042611 MHC protein complex(GO:0042611) MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0000786 nucleosome(GO:0000786)
0.0 1.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 5.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 8.9 GO:0019862 IgA binding(GO:0019862)
0.5 2.9 GO:0050436 microfibril binding(GO:0050436)
0.4 1.2 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
0.3 0.8 GO:0002113 interleukin-33 binding(GO:0002113)
0.3 2.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 2.3 GO:0004064 arylesterase activity(GO:0004064)
0.2 1.6 GO:0034711 inhibin binding(GO:0034711)
0.2 1.4 GO:0043237 laminin-1 binding(GO:0043237)
0.1 1.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 1.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.3 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.5 GO:0004802 transketolase activity(GO:0004802)
0.1 0.7 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 1.3 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 2.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 2.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.6 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 5.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 1.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.0 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 2.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 5.0 GO:0003823 antigen binding(GO:0003823)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 1.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 3.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 2.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.1 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 4.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.8 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 2.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 3.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 2.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)