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Illumina Body Map 2 (GSE30611)

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Results for HOXC6_HOXA7

Z-value: 0.89

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Transcription factors associated with HOXC6_HOXA7

Gene Symbol Gene ID Gene Info
ENSG00000197757.8 homeobox C6
ENSG00000122592.8 homeobox A7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC6hg38_v1_chr12_+_53994874_53994944-0.125.0e-01Click!
HOXA7hg38_v1_chr7_-_27156646_271566930.125.2e-01Click!

Activity profile of HOXC6_HOXA7 motif

Sorted Z-values of HOXC6_HOXA7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_89027700 4.34 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr9_+_122371014 4.20 ENST00000362012.7
prostaglandin-endoperoxide synthase 1
chr9_+_122371036 3.83 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
prostaglandin-endoperoxide synthase 1
chr2_+_90172802 3.46 ENST00000390277.3
immunoglobulin kappa variable 3D-11
chr9_+_122370523 3.29 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chr2_-_89143133 3.27 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr19_+_49513353 2.89 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr6_+_113857333 2.74 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr2_+_90038848 2.54 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr2_+_87338511 2.47 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr1_-_113871665 2.44 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
protein tyrosine phosphatase non-receptor type 22
chr2_+_90234809 2.31 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr14_-_106470788 2.19 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr6_+_26365159 1.96 ENST00000532865.5
ENST00000396934.7
ENST00000508906.6
ENST00000530653.5
ENST00000527417.5
butyrophilin subfamily 3 member A2
chr6_+_26365215 1.92 ENST00000527422.5
ENST00000356386.6
ENST00000396948.5
butyrophilin subfamily 3 member A2
chr6_+_130018565 1.88 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr18_-_49492305 1.83 ENST00000615479.4
ENST00000583637.5
ENST00000618613.5
ENST00000615760.4
ENST00000578528.1
ENST00000578532.5
ENST00000580387.5
ENST00000579248.5
ENST00000580261.6
ENST00000581373.5
ENST00000618619.4
ENST00000617346.4
ENST00000583036.5
ENST00000332968.11
ribosomal protein L17
RPL17-C18orf32 readthrough
chr6_+_26365176 1.80 ENST00000377708.7
butyrophilin subfamily 3 member A2
chr13_+_53028806 1.79 ENST00000219022.3
olfactomedin 4
chr1_+_202348687 1.76 ENST00000608999.6
ENST00000391959.5
ENST00000480184.5
protein phosphatase 1 regulatory subunit 12B
chr4_+_150582119 1.75 ENST00000317605.6
mab-21 like 2
chr12_+_56041893 1.72 ENST00000552361.1
ENST00000646449.2
ribosomal protein S26
chr19_-_54313074 1.70 ENST00000486742.2
ENST00000432233.8
leukocyte immunoglobulin like receptor A5
chr2_-_88979016 1.69 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr9_-_92404559 1.68 ENST00000262551.8
ENST00000375561.10
osteoglycin
chr1_-_92486916 1.56 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr11_+_60056587 1.47 ENST00000395032.6
ENST00000358152.6
membrane spanning 4-domains A3
chr16_+_11965193 1.37 ENST00000053243.6
ENST00000396495.3
TNF receptor superfamily member 17
chr12_-_9869345 1.29 ENST00000228438.3
C-type lectin domain family 2 member B
chr11_+_60056653 1.21 ENST00000278865.8
membrane spanning 4-domains A3
chr15_+_58138368 1.20 ENST00000219919.9
ENST00000536493.1
aquaporin 9
chr1_-_150765785 1.15 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
cathepsin S
chr14_+_21997531 1.13 ENST00000390445.2
T cell receptor alpha variable 17
chr6_+_26402237 1.13 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
butyrophilin subfamily 3 member A1
chr17_-_48610971 1.12 ENST00000239165.9
homeobox B7
chr12_+_130953898 1.07 ENST00000261654.10
adhesion G protein-coupled receptor D1
chr3_+_111911604 1.05 ENST00000495180.1
pleckstrin homology like domain family B member 2
chr4_+_168497044 1.02 ENST00000505667.6
palladin, cytoskeletal associated protein
chr3_+_136930469 1.01 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr1_+_66354375 1.00 ENST00000480109.2
phosphodiesterase 4B
chr8_-_33567118 0.99 ENST00000256257.2
ring finger protein 122
chr6_+_26402289 0.98 ENST00000414912.2
butyrophilin subfamily 3 member A1
chr15_+_67125707 0.96 ENST00000540846.6
SMAD family member 3
chr1_+_160400543 0.94 ENST00000368061.3
VANGL planar cell polarity protein 2
chr2_+_151357583 0.91 ENST00000243347.5
TNF alpha induced protein 6
chr7_+_142300924 0.89 ENST00000455382.2
T cell receptor beta variable 2
chr12_-_91179517 0.88 ENST00000551354.1
decorin
chr4_+_168497066 0.88 ENST00000261509.10
palladin, cytoskeletal associated protein
chr13_+_30735523 0.86 ENST00000380490.5
arachidonate 5-lipoxygenase activating protein
chr7_+_93921720 0.83 ENST00000248564.6
G protein subunit gamma 11
chr1_+_192716132 0.82 ENST00000647225.1
ENST00000443181.2
ribosomal protein S27a pseudogene 5
chr18_-_63661884 0.81 ENST00000332821.8
ENST00000283752.10
serpin family B member 3
chr2_+_201233443 0.75 ENST00000392263.6
ENST00000264274.13
ENST00000432109.6
ENST00000264275.9
ENST00000450491.5
ENST00000440732.5
ENST00000392258.7
caspase 8
chr12_+_40310431 0.74 ENST00000681696.1
leucine rich repeat kinase 2
chr14_+_61697622 0.71 ENST00000539097.2
hypoxia inducible factor 1 subunit alpha
chr3_-_39280021 0.70 ENST00000399220.3
C-X3-C motif chemokine receptor 1
chr7_-_22822829 0.69 ENST00000358435.9
ENST00000621567.1
translocase of outer mitochondrial membrane 7
chr4_-_119322128 0.68 ENST00000274024.4
fatty acid binding protein 2
chr14_-_53958757 0.67 ENST00000559642.1
bone morphogenetic protein 4
chr6_+_106360668 0.67 ENST00000633556.3
crystallin beta-gamma domain containing 1
chr18_+_34978244 0.66 ENST00000436190.6
microtubule associated protein RP/EB family member 2
chr11_-_107858777 0.66 ENST00000525815.6
solute carrier family 35 member F2
chr2_+_206159580 0.66 ENST00000236957.9
ENST00000392221.5
ENST00000445505.5
eukaryotic translation elongation factor 1 beta 2
chr9_-_20382461 0.65 ENST00000380321.5
ENST00000629733.3
MLLT3 super elongation complex subunit
chr3_-_165078480 0.65 ENST00000264382.8
sucrase-isomaltase
chr7_-_22822779 0.65 ENST00000372879.8
translocase of outer mitochondrial membrane 7
chr12_-_10130143 0.65 ENST00000298523.9
ENST00000396484.6
ENST00000310002.4
ENST00000304084.13
C-type lectin domain containing 7A
chr19_+_48695952 0.63 ENST00000522966.2
ENST00000425340.3
ENST00000391876.5
fucosyltransferase 2
chr18_+_34976928 0.62 ENST00000591734.5
ENST00000413393.5
ENST00000589180.5
ENST00000587359.5
microtubule associated protein RP/EB family member 2
chr1_-_160954801 0.62 ENST00000368029.4
intelectin 2
chr11_+_35201083 0.61 ENST00000526553.6
CD44 molecule (Indian blood group)
chr14_+_21621801 0.60 ENST00000542354.1
T cell receptor alpha variable 1-1
chr11_-_102780620 0.60 ENST00000279441.9
ENST00000539681.1
matrix metallopeptidase 10
chr14_-_22957128 0.59 ENST00000342454.12
ENST00000555986.5
ENST00000554516.5
ENST00000347758.6
ENST00000206474.11
ENST00000555040.5
HAUS augmin like complex subunit 4
chr14_-_89619118 0.59 ENST00000345097.8
ENST00000555855.5
ENST00000555353.5
forkhead box N3
chr14_-_22957061 0.57 ENST00000557591.5
ENST00000541587.6
ENST00000490506.5
ENST00000554406.1
HAUS augmin like complex subunit 4
chr2_+_201183120 0.56 ENST00000272879.9
ENST00000286186.11
ENST00000374650.7
ENST00000346817.9
ENST00000313728.11
ENST00000448480.1
caspase 10
chr16_-_28623560 0.56 ENST00000350842.8
sulfotransferase family 1A member 1
chr1_+_50970234 0.55 ENST00000371761.4
cyclin dependent kinase inhibitor 2C
chr1_+_226063466 0.55 ENST00000666609.1
ENST00000661429.1
H3.3 histone A
chr2_+_206159884 0.54 ENST00000392222.7
eukaryotic translation elongation factor 1 beta 2
chr16_+_53435612 0.54 ENST00000544405.6
RB transcriptional corepressor like 2
chr3_+_178419123 0.53 ENST00000614557.1
ENST00000455307.5
ENST00000436432.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript)
long intergenic non-protein coding RNA 1014
chr12_-_10130241 0.53 ENST00000353231.9
ENST00000525605.1
C-type lectin domain containing 7A
chr12_-_91179472 0.53 ENST00000550099.5
ENST00000546391.5
decorin
chr4_-_39977836 0.52 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr4_+_107824555 0.52 ENST00000394684.8
sphingomyelin synthase 2
chr3_+_132597260 0.51 ENST00000249887.3
atypical chemokine receptor 4
chr12_-_91179355 0.51 ENST00000550563.5
ENST00000546370.5
decorin
chr14_+_22096017 0.50 ENST00000390452.2
T cell receptor delta variable 1
chr4_-_137532452 0.50 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr6_+_26440472 0.50 ENST00000494393.5
ENST00000482451.5
ENST00000471353.5
ENST00000361232.7
ENST00000487627.5
ENST00000496719.1
ENST00000244519.7
ENST00000490254.5
ENST00000487272.1
butyrophilin subfamily 3 member A3
chr17_+_50746614 0.50 ENST00000513969.5
ENST00000503728.1
LUC7 like 3 pre-mRNA splicing factor
chr6_+_158649997 0.49 ENST00000360448.8
ENST00000367081.7
ENST00000611299.5
synaptotagmin like 3
chr7_+_150405146 0.48 ENST00000498682.3
ENST00000641717.1
novel zinc finger protein
chr10_+_84425148 0.47 ENST00000493409.5
coiled-coil serine rich protein 2
chr4_-_48114523 0.47 ENST00000506073.1
TXK tyrosine kinase
chr6_-_109381739 0.46 ENST00000504373.2
CD164 molecule
chr14_-_22957100 0.46 ENST00000555367.5
HAUS augmin like complex subunit 4
chr4_-_36243939 0.45 ENST00000506189.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_-_107858561 0.43 ENST00000375682.8
solute carrier family 35 member F2
chr4_-_106368772 0.42 ENST00000638719.4
GIMAP family P-loop NTPase domain containing 1
chr7_+_134843884 0.42 ENST00000445569.6
caldesmon 1
chr5_+_40909490 0.42 ENST00000313164.10
complement C7
chr10_+_84424919 0.41 ENST00000543283.2
ENST00000494586.5
coiled-coil serine rich protein 2
chr2_+_33458043 0.40 ENST00000437184.5
RAS guanyl releasing protein 3
chr18_-_55423757 0.40 ENST00000675707.1
transcription factor 4
chr1_+_117001744 0.39 ENST00000256652.8
ENST00000682167.1
ENST00000369470.1
CD101 molecule
chr12_-_89526011 0.39 ENST00000313546.8
POC1 centriolar protein B
chr14_+_71933116 0.38 ENST00000553530.5
ENST00000556437.5
regulator of G protein signaling 6
chr9_-_20382448 0.38 ENST00000491137.5
MLLT3 super elongation complex subunit
chr6_-_41733690 0.37 ENST00000419396.6
ENST00000678831.1
ENST00000394283.5
transcription factor EB
chr16_+_11965234 0.37 ENST00000562385.1
TNF receptor superfamily member 17
chr6_+_28124596 0.36 ENST00000340487.5
zinc finger and SCAN domain containing 16
chr5_+_163503075 0.36 ENST00000280969.9
methionine adenosyltransferase 2B
chr7_+_150405668 0.36 ENST00000642087.1
novel zinc finger protein
chr10_-_49188380 0.35 ENST00000374153.7
ENST00000374148.1
ENST00000374151.7
transmembrane protein 273
chr2_-_175181663 0.34 ENST00000392541.3
ENST00000284727.9
ENST00000409194.5
ATP synthase membrane subunit c locus 3
chr15_+_64387828 0.34 ENST00000261884.8
thyroid hormone receptor interactor 4
chr2_-_40453438 0.34 ENST00000455476.5
solute carrier family 8 member A1
chr18_+_34978415 0.33 ENST00000588349.6
microtubule associated protein RP/EB family member 2
chrX_+_1591590 0.33 ENST00000313871.9
ENST00000381261.8
A-kinase anchoring protein 17A
chr14_-_22957022 0.33 ENST00000556915.5
HAUS augmin like complex subunit 4
chr17_-_50129753 0.33 ENST00000511964.1
sterile alpha motif domain containing 14
chr2_+_201182873 0.32 ENST00000360132.7
caspase 10
chrX_+_100584928 0.32 ENST00000373031.5
tenomodulin
chr14_+_56117702 0.31 ENST00000559044.5
pellino E3 ubiquitin protein ligase family member 2
chr5_+_141245384 0.31 ENST00000623671.1
ENST00000231173.6
protocadherin beta 15
chr6_+_149400260 0.30 ENST00000326669.6
small ubiquitin like modifier 4
chr2_+_90209873 0.30 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr12_-_89526164 0.30 ENST00000548729.5
POC1B-GALNT4 readthrough
chr8_+_32614361 0.29 ENST00000522569.1
neuregulin 1
chr7_+_150323239 0.29 ENST00000323078.7
ENST00000493307.1
ENST00000359623.9
leucine rich repeat containing 61
chr11_+_73787853 0.28 ENST00000310614.12
ENST00000497094.6
ENST00000411840.6
ENST00000535277.5
ENST00000398483.7
ENST00000542303.5
mitochondrial ribosomal protein L48
chr11_+_33039996 0.28 ENST00000432887.5
ENST00000528898.1
ENST00000531632.6
t-complex 11 like 1
chr5_+_67004618 0.28 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr3_-_157503375 0.27 ENST00000362010.7
ventricular zone expressed PH domain containing 1
chr3_-_157503339 0.27 ENST00000392833.6
ventricular zone expressed PH domain containing 1
chr10_-_49188312 0.26 ENST00000453436.5
ENST00000474718.5
transmembrane protein 273
chr1_-_120054225 0.25 ENST00000602566.6
notch receptor 2
chr17_+_59155726 0.25 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
proline rich 11
chr3_+_138621225 0.25 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr2_-_88861920 0.25 ENST00000390242.2
immunoglobulin kappa joining 1
chr16_-_28623330 0.24 ENST00000677940.1
novel protein
chrX_-_16869840 0.23 ENST00000380084.8
RB binding protein 7, chromatin remodeling factor
chr11_+_121576760 0.23 ENST00000532694.5
ENST00000534286.5
sortilin related receptor 1
chr17_-_74776323 0.22 ENST00000582870.5
ENST00000581136.5
ENST00000579218.5
ENST00000583476.5
ENST00000580301.5
ENST00000583757.5
ENST00000357814.8
ENST00000582524.5
N-acetyltransferase 9 (putative)
chr17_-_40799939 0.22 ENST00000306658.8
keratin 28
chr2_+_186694007 0.22 ENST00000304698.10
family with sequence similarity 171 member B
chr11_+_2384603 0.22 ENST00000527343.5
ENST00000464784.6
CD81 molecule
chr2_+_168901290 0.21 ENST00000429379.2
ENST00000375363.8
ENST00000421979.1
glucose-6-phosphatase catalytic subunit 2
chr4_-_169612571 0.21 ENST00000507142.6
ENST00000510533.5
ENST00000439128.6
ENST00000511633.5
ENST00000512193.5
NIMA related kinase 1
chr3_+_158801926 0.21 ENST00000622669.4
ENST00000392813.8
ENST00000415822.8
ENST00000651862.1
ENST00000264266.12
major facilitator superfamily domain containing 1
chrX_-_14029877 0.20 ENST00000680255.1
ENST00000380523.8
ENST00000398355.7
gem nuclear organelle associated protein 8
chr15_-_75455767 0.20 ENST00000360439.8
SIN3 transcription regulator family member A
chr8_-_92103270 0.20 ENST00000518832.1
RUNX1 partner transcriptional co-repressor 1
chr5_+_75611182 0.19 ENST00000672850.1
ENST00000672844.1
ankyrin repeat and death domain containing 1B
chr1_+_84181630 0.19 ENST00000610457.1
protein kinase cAMP-activated catalytic subunit beta
chr10_+_113126670 0.19 ENST00000369389.6
transcription factor 7 like 2
chr5_+_55160161 0.18 ENST00000296734.6
ENST00000515370.1
ENST00000503787.6
glutathione peroxidase 8 (putative)
chr6_+_46793379 0.18 ENST00000230588.9
ENST00000611727.2
meprin A subunit alpha
chr2_+_26401909 0.18 ENST00000288710.7
dynein regulatory complex subunit 1
chr2_+_24793098 0.18 ENST00000473706.5
centromere protein O
chr2_-_150539011 0.18 ENST00000439275.1
Rho family GTPase 3
chr8_-_41309434 0.17 ENST00000220772.8
secreted frizzled related protein 1
chr3_-_167474026 0.17 ENST00000466903.1
ENST00000264677.8
serpin family I member 2
chr13_-_30306997 0.17 ENST00000380617.7
ENST00000441394.1
katanin catalytic subunit A1 like 1
chr19_+_57394183 0.16 ENST00000597410.1
novel protein
chr11_+_124566660 0.16 ENST00000641670.1
olfactory receptor family 8 subfamily A member 1
chr12_-_10130082 0.15 ENST00000533022.5
C-type lectin domain containing 7A
chr10_+_52128343 0.15 ENST00000672084.1
protein kinase cGMP-dependent 1
chr6_-_41734160 0.15 ENST00000424495.2
ENST00000420312.6
transcription factor EB
chr3_+_45886501 0.15 ENST00000395963.2
C-C motif chemokine receptor 9
chr2_-_133568393 0.15 ENST00000317721.10
ENST00000405974.7
ENST00000409261.6
ENST00000409213.5
NCK associated protein 5
chr8_-_61689768 0.14 ENST00000517847.6
ENST00000389204.8
ENST00000517661.5
ENST00000517903.5
ENST00000522603.5
ENST00000541428.5
ENST00000522349.5
ENST00000522835.5
ENST00000518306.5
aspartate beta-hydroxylase
chr3_+_138621207 0.14 ENST00000464668.5
Fas apoptotic inhibitory molecule
chr10_+_18260715 0.14 ENST00000615785.4
ENST00000617363.4
ENST00000396576.6
calcium voltage-gated channel auxiliary subunit beta 2
chr1_+_84144260 0.14 ENST00000370685.7
protein kinase cAMP-activated catalytic subunit beta
chr6_+_30061231 0.13 ENST00000376782.6
ENST00000359374.8
ENST00000376785.2
ENST00000332435.10
RNA polymerase I subunit H
chr12_-_50249883 0.13 ENST00000550592.1
LIM domain and actin binding 1
chr19_+_48900798 0.13 ENST00000424608.1
nucleobindin 1
chr6_-_138512493 0.13 ENST00000533765.1
NHS like 1
chr6_-_129861278 0.12 ENST00000368143.6
transmembrane protein 244
chr10_-_114685000 0.12 ENST00000369256.6
actin binding LIM protein 1
chr1_+_205256189 0.11 ENST00000329800.7
transmembrane and coiled-coil domain family 2
chr4_-_151227881 0.11 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr6_-_17706852 0.11 ENST00000262077.3
nucleoporin 153
chr18_+_58341038 0.11 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr11_-_8835702 0.11 ENST00000534248.5
ENST00000530959.5
ENST00000531578.1
ENST00000533225.5
DENN domain containing 2B
chrX_-_107118783 0.10 ENST00000372487.5
ENST00000372479.7
RNA binding motif protein 41
chr11_-_5778667 0.10 ENST00000317093.2
olfactory receptor family 52 subfamily N member 5
chr6_+_151807188 0.10 ENST00000446550.1
estrogen receptor 1
chr3_-_194468227 0.10 ENST00000446356.1
ATPase 13A3
chr1_-_201171545 0.09 ENST00000367333.6
transmembrane protein 9
chr4_-_67963441 0.08 ENST00000508048.6
transmembrane serine protease 11A
chr12_-_89526253 0.08 ENST00000547474.1
POC1B-GALNT4 readthrough
chr1_-_66801276 0.07 ENST00000304526.3
insulin like 5
chr4_+_140524179 0.07 ENST00000507667.1
ELMO domain containing 2
chr12_-_52367478 0.06 ENST00000257901.7
keratin 85
chr21_-_30166782 0.06 ENST00000286808.5
claudin 17

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC6_HOXA7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.5 1.6 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.5 11.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.5 2.4 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.4 1.2 GO:0034769 basement membrane disassembly(GO:0034769)
0.3 1.0 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.3 0.8 GO:0035425 autocrine signaling(GO:0035425)
0.2 0.7 GO:1903125 regulation of thioredoxin peroxidase activity(GO:1903123) negative regulation of thioredoxin peroxidase activity(GO:1903124) negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation(GO:1903125) Wnt signalosome assembly(GO:1904887) negative regulation of peroxidase activity(GO:2000469)
0.2 1.2 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.2 0.9 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.2 7.8 GO:0072643 interferon-gamma secretion(GO:0072643)
0.2 0.7 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.1 0.7 GO:0052148 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 1.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.7 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 1.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 1.0 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.7 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 1.8 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.1 0.3 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 1.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.6 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 3.3 GO:0003094 glomerular filtration(GO:0003094)
0.1 0.2 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 2.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.5 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 2.7 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.9 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.9 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 1.3 GO:0042832 defense response to protozoan(GO:0042832)
0.1 0.2 GO:0014034 neural crest cell fate commitment(GO:0014034) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 1.1 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 1.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 12.7 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.6 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 1.1 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 6.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.7 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.1 GO:0075732 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
0.0 0.6 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.5 GO:0044557 relaxation of smooth muscle(GO:0044557)
0.0 0.2 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.3 GO:0097338 response to clozapine(GO:0097338)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.9 GO:0030728 ovulation(GO:0030728)
0.0 0.6 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.3 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.5 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.2 GO:0060413 pulmonary valve development(GO:0003177) pulmonary valve morphogenesis(GO:0003184) atrial septum morphogenesis(GO:0060413)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.0 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 1.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0001674 female germ cell nucleus(GO:0001674)
0.7 3.3 GO:0071753 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.3 0.9 GO:0060187 cell pole(GO:0060187)
0.2 0.7 GO:0032473 cytoplasmic side of mitochondrial outer membrane(GO:0032473) caveola neck(GO:0099400)
0.2 1.2 GO:0036021 endolysosome lumen(GO:0036021)
0.1 1.9 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 2.0 GO:0070652 HAUS complex(GO:0070652)
0.1 0.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 1.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 11.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 2.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.7 GO:0045180 basal cortex(GO:0045180)
0.0 1.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 2.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 1.9 GO:0002102 podosome(GO:0002102)
0.0 1.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 4.3 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 1.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 2.7 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.1 GO:0031672 A band(GO:0031672)
0.0 2.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.7 GO:0043202 lysosomal lumen(GO:0043202)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.7 2.9 GO:0019770 IgG receptor activity(GO:0019770)
0.2 0.7 GO:0034211 GTP-dependent protein kinase activity(GO:0034211) peroxidase inhibitor activity(GO:0036479)
0.2 1.2 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.2 1.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 0.6 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.2 0.7 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.2 0.9 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 1.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 1.0 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.6 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 1.3 GO:0015266 protein channel activity(GO:0015266)
0.1 0.5 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 18.6 GO:0003823 antigen binding(GO:0003823)
0.0 1.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 1.3 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 2.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 1.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 3.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.7 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.3 GO:0004691 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.7 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 1.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 10.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 3.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis