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Illumina Body Map 2 (GSE30611)
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Results for HOXC9
Z-value: 1.28
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Transcription factors associated with HOXC9
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXC9 | hg38_v1_chr12_+_54000096_54000180 | -0.35 | 4.9e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXC9
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 11.2 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.8 | 7.5 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.3 | 5.3 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.3 | 5.2 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 0.9 | 4.4 | GO:0090290 | positive regulation of osteoclast proliferation(GO:0090290) |
| 0.3 | 4.4 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.1 | 3.9 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.4 | 3.5 | GO:0051552 | flavone metabolic process(GO:0051552) |
| 0.0 | 3.1 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
| 0.2 | 2.9 | GO:0009812 | flavonoid metabolic process(GO:0009812) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.5 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 5.8 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 4.9 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 4.8 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.3 | 4.3 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.3 | 3.7 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 3.2 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.1 | 3.1 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 2.9 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 2.9 | GO:0035578 | azurophil granule lumen(GO:0035578) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 11.4 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 7.7 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 1.9 | 7.5 | GO:0061609 | fructose-1-phosphate aldolase activity(GO:0061609) |
| 0.0 | 5.4 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.4 | 5.3 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.0 | 4.4 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.1 | 4.0 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.2 | 3.9 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.1 | 3.9 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 3.9 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.5 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 4.3 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 3.8 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 3.7 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 2.8 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 2.8 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 2.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 2.0 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 1.5 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 1.4 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 9.6 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 8.8 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.1 | 8.7 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 5.7 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.2 | 4.3 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 4.1 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.2 | 3.9 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 3.6 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 3.5 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.1 | 3.4 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |