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Illumina Body Map 2 (GSE30611)

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Results for HOXC9

Z-value: 1.28

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Transcription factors associated with HOXC9

Gene Symbol Gene ID Gene Info
ENSG00000180806.5 homeobox C9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC9hg38_v1_chr12_+_54000096_54000180-0.354.9e-02Click!

Activity profile of HOXC9 motif

Sorted Z-values of HOXC9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_101435760 4.35 ENST00000647789.2
ENST00000616752.1
aldolase, fructose-bisphosphate B
chr4_+_154563003 4.32 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr4_+_68815991 3.73 ENST00000265403.12
ENST00000458688.2
UDP glucuronosyltransferase family 2 member B10
chr4_-_71784046 3.41 ENST00000513476.5
ENST00000273951.13
GC vitamin D binding protein
chr9_-_101442403 3.17 ENST00000648758.1
aldolase, fructose-bisphosphate B
chrX_+_106693838 3.09 ENST00000324342.7
ring finger protein 128
chr11_-_35360050 2.79 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
solute carrier family 1 member 2
chr12_-_62935117 2.73 ENST00000228705.7
protein phosphatase, Mg2+/Mn2+ dependent 1H
chr17_+_70075215 2.63 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
potassium inwardly rectifying channel subfamily J member 16
chr5_+_36606355 2.50 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr1_+_47137435 2.45 ENST00000371891.8
ENST00000371890.7
ENST00000619754.4
ENST00000294337.7
ENST00000620131.1
cytochrome P450 family 4 subfamily A member 22
chr11_-_13496018 2.35 ENST00000529816.1
parathyroid hormone
chrX_+_153072454 2.30 ENST00000421798.5
PNMA family member 6A
chr2_+_233671879 2.13 ENST00000354728.5
UDP glucuronosyltransferase family 1 member A9
chr10_-_112183698 2.12 ENST00000369425.5
ENST00000348367.9
glycerol-3-phosphate acyltransferase, mitochondrial
chr19_-_58353482 2.10 ENST00000263100.8
alpha-1-B glycoprotein
chr8_-_104467042 2.07 ENST00000521573.2
ENST00000351513.7
dihydropyrimidinase
chr9_+_78297143 2.07 ENST00000347159.6
phosphoserine aminotransferase 1
chrX_+_106693751 2.06 ENST00000418562.5
ring finger protein 128
chr11_-_13495984 2.03 ENST00000282091.6
parathyroid hormone
chr12_+_21131187 2.03 ENST00000256958.3
solute carrier organic anion transporter family member 1B1
chr9_-_28670285 1.95 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
leucine rich repeat and Ig domain containing 2
chr6_+_31655888 1.90 ENST00000375916.4
apolipoprotein M
chr5_-_135954962 1.89 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
leukocyte cell derived chemotaxin 2
chr4_-_69214743 1.87 ENST00000446444.2
UDP glucuronosyltransferase family 2 member B11
chr4_+_70734346 1.86 ENST00000513597.5
RUN and FYVE domain containing 3
chr10_-_13302341 1.79 ENST00000396920.7
phytanoyl-CoA 2-hydroxylase
chr6_+_143126183 1.72 ENST00000458219.1
androgen induced 1
chr8_-_80171496 1.69 ENST00000379096.9
ENST00000518937.6
tumor protein D52
chr4_-_175812236 1.63 ENST00000505375.5
glycoprotein M6A
chr8_-_63026179 1.62 ENST00000677919.1
gamma-glutamyl hydrolase
chr1_-_204213943 1.58 ENST00000308302.4
golgi transport 1A
chrX_+_43656289 1.57 ENST00000338702.4
monoamine oxidase A
chr4_-_69760610 1.54 ENST00000310613.8
sulfotransferase family 1B member 1
chr5_-_126595237 1.50 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chr12_-_21604840 1.48 ENST00000261195.3
glycogen synthase 2
chr15_-_89679360 1.43 ENST00000300055.10
perilipin 1
chr15_-_89679411 1.42 ENST00000430628.2
perilipin 1
chr8_-_17697654 1.42 ENST00000297488.10
microtubule associated scaffold protein 1
chr18_-_43277482 1.40 ENST00000255224.8
ENST00000590752.5
ENST00000596867.1
synaptotagmin 4
chr4_-_69760596 1.40 ENST00000510821.1
sulfotransferase family 1B member 1
chr4_+_186227501 1.40 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
kallikrein B1
chr1_+_220690354 1.38 ENST00000294889.6
chromosome 1 open reading frame 115
chr11_+_72189659 1.37 ENST00000393681.6
folate receptor alpha
chr11_-_117316230 1.35 ENST00000313005.11
ENST00000528053.5
beta-secretase 1
chr2_-_199851114 1.34 ENST00000420128.5
ENST00000416668.5
ENST00000622774.2
formiminotransferase cyclodeaminase N-terminal like
chr4_-_68670648 1.33 ENST00000338206.6
UDP glucuronosyltransferase family 2 member B15
chr2_+_233617626 1.33 ENST00000373450.5
UDP glucuronosyltransferase family 1 member A8
chr12_+_20810698 1.33 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr10_-_27240505 1.27 ENST00000375888.5
ENST00000676732.1
acyl-CoA binding domain containing 5
chr17_+_70075317 1.25 ENST00000589377.1
potassium inwardly rectifying channel subfamily J member 16
chr5_+_175861628 1.22 ENST00000509837.5
complexin 2
chr1_+_16043776 1.22 ENST00000375679.9
chloride voltage-gated channel Kb
chr4_+_70734419 1.22 ENST00000502653.5
RUN and FYVE domain containing 3
chr19_-_35812838 1.22 ENST00000653904.2
proline dehydrogenase 2
chr5_-_149063089 1.22 ENST00000512049.5
SH3 domain and tetratricopeptide repeats 2
chr9_+_74497308 1.19 ENST00000376896.8
RAR related orphan receptor B
chr2_+_209579399 1.18 ENST00000360351.8
microtubule associated protein 2
chr2_+_209579598 1.17 ENST00000445941.5
ENST00000673860.1
microtubule associated protein 2
chr1_-_120054225 1.16 ENST00000602566.6
notch receptor 2
chr8_-_80080816 1.15 ENST00000520527.5
ENST00000517427.5
ENST00000379097.7
ENST00000448733.3
tumor protein D52
chr18_+_45615473 1.14 ENST00000255226.11
solute carrier family 14 member 2
chr1_+_163069353 1.13 ENST00000531057.5
ENST00000527809.5
ENST00000367908.8
ENST00000367909.11
regulator of G protein signaling 4
chr8_-_18684033 1.10 ENST00000614430.3
pleckstrin and Sec7 domain containing 3
chr2_-_223602284 1.10 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr6_+_29301701 1.10 ENST00000641895.1
olfactory receptor family 14 subfamily J member 1
chr11_+_22666604 1.09 ENST00000454584.6
growth arrest specific 2
chr16_-_12803785 1.05 ENST00000433677.6
ENST00000261660.4
ENST00000381774.9
calcineurin like phosphoesterase domain containing 1
chr8_-_109974688 1.05 ENST00000297404.1
potassium voltage-gated channel modifier subfamily V member 1
chr11_+_72189528 1.05 ENST00000312293.9
folate receptor alpha
chr8_+_103021027 1.04 ENST00000518857.5
ENST00000395862.7
ENST00000518738.2
ENST00000521514.5
ATPase H+ transporting V1 subunit C1
chr10_-_113854368 1.04 ENST00000369305.1
DNA cross-link repair 1A
chr8_+_17027230 1.04 ENST00000318063.10
mitochondrial calcium uptake family member 3
chr1_+_212791828 1.03 ENST00000532324.5
ENST00000530441.5
ENST00000526641.5
ENST00000531963.5
ENST00000366973.8
ENST00000366974.9
ENST00000526997.5
ENST00000488246.6
TatD DNase domain containing 3
chr2_-_171894227 1.02 ENST00000422440.7
solute carrier family 25 member 12
chr7_-_111784406 1.02 ENST00000664131.1
ENST00000437129.5
dedicator of cytokinesis 4
chr9_+_101185029 1.02 ENST00000395056.2
phospholipid phosphatase related 1
chr14_+_73616844 1.01 ENST00000381139.1
acyl-CoA thioesterase 6
chr4_+_133149278 1.00 ENST00000264360.7
protocadherin 10
chr10_-_125816596 0.99 ENST00000368786.5
uroporphyrinogen III synthase
chr5_-_149063021 0.99 ENST00000515425.6
SH3 domain and tetratricopeptide repeats 2
chr10_-_125816510 0.98 ENST00000650587.1
uroporphyrinogen III synthase
chr12_+_25052220 0.96 ENST00000550945.5
inositol 1,4,5-triphosphate receptor associated 2
chr7_+_138076422 0.96 ENST00000432161.5
aldo-keto reductase family 1 member D1
chr2_-_49973939 0.94 ENST00000630656.1
neurexin 1
chr14_+_19930917 0.93 ENST00000641172.1
ENST00000641429.1
olfactory receptor family 4 subfamily K member 1
chr17_+_69502397 0.93 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chr18_+_45727329 0.93 ENST00000590246.6
solute carrier family 14 member 1 (Kidd blood group)
chr19_-_47471886 0.92 ENST00000236877.11
ENST00000597014.1
solute carrier family 8 member A2
chr8_-_71361860 0.92 ENST00000303824.11
ENST00000645451.1
EYA transcriptional coactivator and phosphatase 1
chr18_-_43277364 0.90 ENST00000593720.1
synaptotagmin 4
chr19_+_42325612 0.89 ENST00000251268.11
multiple EGF like domains 8
chr1_+_92168915 0.88 ENST00000637221.2
BTB domain containing 8
chr7_-_111784448 0.88 ENST00000450156.6
dedicator of cytokinesis 4
chr7_+_7156934 0.86 ENST00000429911.5
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
chr8_-_17722217 0.85 ENST00000381861.7
microtubule associated scaffold protein 1
chr4_-_117085541 0.85 ENST00000310754.5
translocation associated membrane protein 1 like 1
chr9_-_94640130 0.84 ENST00000414122.1
fructose-bisphosphatase 1
chr4_+_56436233 0.84 ENST00000512576.3
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr11_+_22672577 0.83 ENST00000534801.5
growth arrest specific 2
chr11_+_46345368 0.83 ENST00000528615.5
diacylglycerol kinase zeta
chr11_-_119030848 0.83 ENST00000330775.9
ENST00000357590.9
ENST00000538950.5
ENST00000545985.5
solute carrier family 37 member 4
chr11_-_45918789 0.81 ENST00000532681.5
peroxisomal biogenesis factor 16
chr10_-_116849686 0.81 ENST00000674167.1
ENST00000674401.1
ENST00000674326.1
ENST00000674267.1
ENST00000635765.1
heat shock protein family A (Hsp70) member 12A
chr1_+_202416826 0.81 ENST00000466968.1
protein phosphatase 1 regulatory subunit 12B
chr5_+_157269317 0.80 ENST00000618329.4
cytoplasmic FMR1 interacting protein 2
chr7_-_44541262 0.80 ENST00000289547.8
ENST00000546276.5
ENST00000423141.1
NPC1 like intracellular cholesterol transporter 1
chr17_+_69502154 0.80 ENST00000589295.5
mitogen-activated protein kinase kinase 6
chr8_-_18684093 0.80 ENST00000428502.6
pleckstrin and Sec7 domain containing 3
chr9_+_128787331 0.79 ENST00000223865.8
TBC1 domain family member 13
chr18_-_77127935 0.78 ENST00000581878.5
myelin basic protein
chrM_+_10464 0.78 ENST00000361335.1
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L
chr9_-_21305313 0.78 ENST00000610521.2
interferon alpha 5
chr17_-_39225936 0.78 ENST00000333461.6
SH3 and cysteine rich domain 2
chr19_+_21082224 0.78 ENST00000620627.1
zinc finger protein 714
chr2_-_224947030 0.77 ENST00000409592.7
dedicator of cytokinesis 10
chr19_+_21082190 0.77 ENST00000618422.1
ENST00000618008.4
ENST00000425625.5
ENST00000456283.7
zinc finger protein 714
chr3_-_196515315 0.76 ENST00000397537.3
single-pass membrane protein with coiled-coil domains 1
chr2_-_229232039 0.74 ENST00000354069.6
phosphotyrosine interaction domain containing 1
chr17_+_7445491 0.74 ENST00000536404.6
ENST00000576360.1
cholinergic receptor nicotinic beta 1 subunit
chr2_+_209579429 0.73 ENST00000361559.8
microtubule associated protein 2
chr16_-_56519971 0.73 ENST00000682482.1
ENST00000682047.1
ENST00000682205.1
ENST00000682855.1
ENST00000245157.11
ENST00000682470.1
ENST00000682360.1
ENST00000569941.6
ENST00000568104.6
ENST00000684635.1
ENST00000682188.1
ENST00000683858.1
Bardet-Biedl syndrome 2
chr2_-_182242031 0.73 ENST00000358139.6
phosphodiesterase 1A
chr14_+_66824439 0.72 ENST00000555456.1
gephyrin
chr6_+_83193331 0.72 ENST00000369724.5
RWD domain containing 2A
chr2_+_112482133 0.72 ENST00000233336.7
tubulin tyrosine ligase
chr16_+_56451513 0.72 ENST00000562150.5
ENST00000561646.5
ENST00000566157.6
ENST00000568397.1
2-oxoglutarate and iron dependent oxygenase domain containing 1
chr3_+_16265160 0.71 ENST00000627468.2
ENST00000605932.5
ENST00000435829.6
ENST00000285083.10
oxidoreductase NAD binding domain containing 1
chr6_-_52994248 0.70 ENST00000457564.1
ENST00000370960.5
glutathione S-transferase alpha 4
chr2_+_195575968 0.70 ENST00000458054.1
solute carrier family 39 member 10
chr8_-_118951876 0.70 ENST00000297350.9
TNF receptor superfamily member 11b
chr1_+_16022004 0.68 ENST00000439316.6
chloride voltage-gated channel Ka
chr8_+_12951325 0.67 ENST00000400069.7
tRNA methyltransferase 9B (putative)
chr12_-_10939263 0.67 ENST00000537503.2
taste 2 receptor member 14
chr2_-_199850850 0.67 ENST00000420922.6
formiminotransferase cyclodeaminase N-terminal like
chr8_-_30812867 0.67 ENST00000518243.5
protein phosphatase 2 catalytic subunit beta
chr18_-_21703688 0.67 ENST00000584464.1
ENST00000578270.5
abhydrolase domain containing 3, phospholipase
chr3_+_185328886 0.66 ENST00000428617.1
ENST00000443863.5
mitogen-activated protein kinase kinase kinase 13
chr11_-_129024157 0.66 ENST00000392657.7
Rho GTPase activating protein 32
chr16_-_48247533 0.66 ENST00000356608.7
ENST00000569991.1
ATP binding cassette subfamily C member 11
chr20_-_47351877 0.66 ENST00000446894.5
zinc finger MYND-type containing 8
chr3_-_69353677 0.66 ENST00000460709.5
FERM domain containing 4B
chr15_+_43133546 0.65 ENST00000260403.7
transmembrane protein 62
chr11_+_22667069 0.65 ENST00000533363.5
growth arrest specific 2
chr2_-_199456046 0.65 ENST00000428695.5
SATB homeobox 2
chr19_-_3500664 0.65 ENST00000427575.6
deoxyhypusine hydroxylase
chr18_+_58196736 0.64 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr16_-_56519943 0.64 ENST00000683875.1
Bardet-Biedl syndrome 2
chr8_-_92965583 0.64 ENST00000519969.5
triple QxxK/R motif containing
chr3_+_98147479 0.63 ENST00000641380.1
olfactory receptor family 5 subfamily H member 14
chr14_+_52707192 0.63 ENST00000445930.7
ENST00000555339.5
ENST00000556813.1
proteasome 26S subunit, ATPase 6
chr2_+_209579315 0.62 ENST00000392193.5
microtubule associated protein 2
chr2_+_27496830 0.62 ENST00000264717.7
glucokinase regulator
chr18_+_34978415 0.61 ENST00000588349.6
microtubule associated protein RP/EB family member 2
chr14_-_21024092 0.61 ENST00000554398.5
NDRG family member 2
chr16_-_66730216 0.61 ENST00000569320.5
dynein cytoplasmic 1 light intermediate chain 2
chr12_+_25195252 0.61 ENST00000555711.6
ENST00000554266.6
ENST00000556351.6
ENST00000556927.6
ENST00000556402.6
ENST00000553788.6
electron transfer flavoprotein regulatory factor 1
chr18_-_35290184 0.61 ENST00000589178.5
ENST00000592278.1
ENST00000333206.10
ENST00000592211.1
ENST00000420878.7
ENST00000610712.1
ENST00000586922.2
zinc finger and SCAN domain containing 30
novel transcript
chr6_+_75890091 0.61 ENST00000430435.1
myosin VI
chr15_+_101812202 0.60 ENST00000332238.5
olfactory receptor family 4 subfamily F member 15
chr6_-_145735964 0.59 ENST00000640980.1
ENST00000639423.1
ENST00000611340.5
EPM2A glucan phosphatase, laforin
chr1_+_12917625 0.58 ENST00000330881.6
PRAME family member 7
chr13_-_52450590 0.58 ENST00000378060.9
vacuolar protein sorting 36 homolog
chrX_-_15314543 0.58 ENST00000344384.8
ankyrin repeat and SOCS box containing 11
chr12_-_27014300 0.57 ENST00000535819.1
ENST00000543803.5
ENST00000535423.5
ENST00000539741.5
ENST00000343028.9
ENST00000545600.1
ENST00000543088.5
transmembrane 7 superfamily member 3
chr9_+_65675834 0.57 ENST00000377392.9
ENST00000377384.5
ENST00000430059.6
ENST00000429800.6
ENST00000382405.8
ENST00000377395.8
COBW domain containing 5
chr12_+_59689337 0.57 ENST00000261187.8
solute carrier family 16 member 7
chr11_-_63144221 0.57 ENST00000417740.5
ENST00000612278.4
ENST00000326192.5
solute carrier family 22 member 24
chr16_-_56520087 0.56 ENST00000682737.1
Bardet-Biedl syndrome 2
chr7_-_44541318 0.56 ENST00000381160.8
NPC1 like intracellular cholesterol transporter 1
chr8_+_131904071 0.56 ENST00000254624.10
ENST00000522709.5
EFR3 homolog A
chr8_-_92966129 0.56 ENST00000522925.5
ENST00000522903.5
ENST00000537541.1
ENST00000521988.6
ENST00000518748.5
ENST00000519069.5
triple QxxK/R motif containing
chrX_+_153056408 0.56 ENST00000619635.1
PNMA family member 3
chr19_-_3500625 0.56 ENST00000672935.1
deoxyhypusine hydroxylase
chr14_+_52707178 0.55 ENST00000612399.4
proteasome 26S subunit, ATPase 6
chr16_-_66873233 0.55 ENST00000561579.6
NEDD8 activating enzyme E1 subunit 1
chr6_+_26087281 0.55 ENST00000353147.9
ENST00000397022.7
ENST00000352392.8
ENST00000349999.8
ENST00000317896.11
ENST00000470149.5
ENST00000336625.12
ENST00000461397.5
ENST00000488199.5
homeostatic iron regulator
chrX_+_141894666 0.55 ENST00000544766.5
MAGE family member C3
chr5_-_16738341 0.55 ENST00000515803.5
myosin X
chr12_-_55296569 0.54 ENST00000358433.3
olfactory receptor family 6 subfamily C member 6
chr14_-_21023954 0.54 ENST00000554094.5
NDRG family member 2
chr11_+_121129964 0.54 ENST00000645008.1
tectorin alpha
chr12_+_19205257 0.54 ENST00000538305.5
pleckstrin homology domain containing A5
chr5_-_35991433 0.54 ENST00000507113.5
ENST00000333811.5
UDP glycosyltransferase family 3 member A1
chr1_+_12464912 0.54 ENST00000543766.2
vacuolar protein sorting 13 homolog D
chr11_-_5154757 0.54 ENST00000380367.3
olfactory receptor family 52 subfamily A member 1
chr6_+_158312459 0.53 ENST00000367097.8
TUB like protein 4
chr3_-_57292676 0.53 ENST00000389601.3
ENST00000487349.6
ankyrin repeat and SOCS box containing 14
chr18_+_58341038 0.53 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr19_-_14884761 0.52 ENST00000642123.1
olfactory receptor family 7 subfamily A member 17
chr4_+_69280472 0.52 ENST00000335568.10
ENST00000511240.1
UDP glucuronosyltransferase family 2 member B28
chr12_-_89656051 0.52 ENST00000261173.6
ATPase plasma membrane Ca2+ transporting 1
chr9_+_128787243 0.51 ENST00000372648.10
TBC1 domain family member 13
chr11_+_49027501 0.51 ENST00000622138.4
tripartite motif containing 49B
chr12_+_25195230 0.51 ENST00000381356.9
electron transfer flavoprotein regulatory factor 1
chr3_+_138621225 0.51 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr19_-_20565808 0.51 ENST00000596797.1
zinc finger protein 737
chr2_-_2324323 0.51 ENST00000648339.1
ENST00000647694.1
myelin transcription factor 1 like
chr16_+_72056153 0.51 ENST00000576168.6
ENST00000567185.7
ENST00000567612.2
haptoglobin
chr1_-_13284169 0.51 ENST00000621519.4
PRAME family member 8

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.8 2.4 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.8 7.5 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.7 2.1 GO:0006212 uracil catabolic process(GO:0006212)
0.5 2.0 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.5 1.9 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.4 1.8 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.4 2.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.4 3.5 GO:0051552 flavone metabolic process(GO:0051552)
0.4 1.5 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.4 2.5 GO:0002933 lipid hydroxylation(GO:0002933)
0.3 1.4 GO:0051919 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.3 2.1 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
0.3 5.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.3 1.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 5.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 1.6 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.3 4.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 1.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 0.9 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.3 1.9 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.3 2.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 1.9 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.2 0.7 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 2.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 0.7 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.2 0.7 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.2 0.8 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.2 0.8 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.2 1.0 GO:0030573 bile acid catabolic process(GO:0030573)
0.2 0.7 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.2 0.6 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) response to iron ion starvation(GO:1990641)
0.2 2.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.2 0.2 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.2 0.5 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.2 0.5 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 2.9 GO:0009812 flavonoid metabolic process(GO:0009812)
0.2 2.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.9 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 1.3 GO:0030242 pexophagy(GO:0030242)
0.1 0.7 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.8 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 1.6 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.7 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.6 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 1.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.9 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 1.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 2.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.7 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 1.9 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.8 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 1.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.4 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 2.7 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.4 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.3 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.5 GO:0061324 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 1.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 1.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 1.1 GO:2000828 post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.1 0.6 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.4 GO:0071874 astrocyte activation involved in immune response(GO:0002265) microglia differentiation(GO:0014004) microglia development(GO:0014005) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.1 0.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 1.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.3 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.6 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 1.9 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 0.2 GO:0032913 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.1 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.7 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 3.9 GO:0010107 potassium ion import(GO:0010107)
0.1 0.2 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 1.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.8 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.4 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.3 GO:0089718 amino acid import across plasma membrane(GO:0089718)
0.0 1.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 2.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 1.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 1.4 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.8 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.3 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.5 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.9 GO:2000821 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) regulation of grooming behavior(GO:2000821)
0.0 0.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 11.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 1.9 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 3.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.0 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.7 GO:0015865 purine nucleotide transport(GO:0015865)
0.0 0.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.3 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.5 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 1.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.3 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 1.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 1.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.7 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.8 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 2.6 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 2.9 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.1 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.3 GO:0046677 response to antibiotic(GO:0046677)
0.0 1.0 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.5 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.4 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.0 GO:0042704 uterine wall breakdown(GO:0042704)
0.0 0.7 GO:0030516 regulation of axon extension(GO:0030516)
0.0 0.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 1.4 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0044550 secondary metabolite biosynthetic process(GO:0044550)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0032127 dense core granule membrane(GO:0032127)
0.5 1.9 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.5 1.4 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.3 3.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 4.3 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.6 GO:0000814 ESCRT II complex(GO:0000814)
0.2 1.9 GO:0034464 BBSome(GO:0034464)
0.2 1.0 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.2 1.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 7.5 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.7 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.4 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 1.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.5 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.6 GO:1990357 terminal web(GO:1990357)
0.1 2.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.5 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.8 GO:0033269 internode region of axon(GO:0033269)
0.1 0.5 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.4 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 3.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 1.1 GO:0031045 dense core granule(GO:0031045)
0.0 2.9 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 1.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 2.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 1.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 1.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 4.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 2.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 4.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.3 GO:0032420 stereocilium(GO:0032420)
0.0 1.3 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 5.8 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 1.0 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 3.2 GO:0043197 dendritic spine(GO:0043197)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.5 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.9 3.4 GO:1902271 D3 vitamins binding(GO:1902271)
0.6 2.4 GO:0061714 folic acid receptor activity(GO:0061714)
0.5 2.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.4 2.1 GO:0004157 nucleobase binding(GO:0002054) dihydropyrimidinase activity(GO:0004157)
0.4 5.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 1.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.3 2.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.3 0.9 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.3 0.8 GO:0004638 phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.3 2.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.2 2.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 0.7 GO:0061599 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 2.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 0.7 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.2 11.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 0.8 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 1.0 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.2 2.5 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2 0.6 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.2 1.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 0.5 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.2 3.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 0.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 0.6 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 1.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.6 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.8 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 1.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 4.0 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.7 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 1.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 2.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 3.9 GO:0002162 dystroglycan binding(GO:0002162)
0.1 2.0 GO:0005542 folic acid binding(GO:0005542)
0.1 1.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 0.3 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.5 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 1.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.0 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.5 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.3 GO:0043273 CTPase activity(GO:0043273)
0.1 1.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.5 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 1.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 1.6 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 2.2 GO:0008483 transaminase activity(GO:0008483)
0.1 0.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 3.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.8 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 1.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 1.6 GO:0071949 FAD binding(GO:0071949)
0.0 1.1 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 2.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.0 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 1.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 2.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.6 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.7 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.6 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 3.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.9 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 2.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 7.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 4.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 1.0 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0019841 retinol binding(GO:0019841)
0.0 1.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 5.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 1.5 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.5 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.8 GO:0004497 monooxygenase activity(GO:0004497)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 4.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 3.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 3.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 2.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 4.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 3.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 8.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 3.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 3.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 2.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 2.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 2.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 5.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.5 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 4.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 8.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 3.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.7 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 3.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination