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Illumina Body Map 2 (GSE30611)

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Results for HOXD1

Z-value: 0.69

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Transcription factors associated with HOXD1

Gene Symbol Gene ID Gene Info
ENSG00000128645.15 homeobox D1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD1hg38_v1_chr2_+_176188658_1761886740.373.8e-02Click!

Activity profile of HOXD1 motif

Sorted Z-values of HOXD1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_26572254 3.82 ENST00000529533.6
mucin 15, cell surface associated
chr11_-_26572102 3.25 ENST00000455601.6
mucin 15, cell surface associated
chr11_-_26572130 3.04 ENST00000527569.1
mucin 15, cell surface associated
chr8_+_91249307 2.94 ENST00000309536.6
ENST00000276609.8
solute carrier family 26 member 7
chr11_+_72189659 1.98 ENST00000393681.6
folate receptor alpha
chr11_+_72189528 1.87 ENST00000312293.9
folate receptor alpha
chr17_-_7263959 1.38 ENST00000571932.2
claudin 7
chr5_-_97142579 1.37 ENST00000274382.9
limb and CNS expressed 1
chr11_+_102047422 1.23 ENST00000434758.7
ENST00000526781.5
ENST00000534360.1
cilia and flagella associated protein 300
chr2_+_134838610 1.20 ENST00000356140.10
ENST00000392928.5
aminocarboxymuconate semialdehyde decarboxylase
chr3_+_2892199 1.16 ENST00000397459.6
contactin 4
chr1_-_201171545 1.15 ENST00000367333.6
transmembrane protein 9
chr6_-_110179995 1.04 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASP family member 1
chr20_-_51802509 1.02 ENST00000371539.7
ENST00000217086.9
spalt like transcription factor 4
chr13_+_77741160 0.94 ENST00000314070.9
ENST00000351546.7
SLAIN motif family member 1
chrX_+_115593570 0.92 ENST00000539310.5
plastin 3
chr12_-_23584600 0.91 ENST00000396007.6
SRY-box transcription factor 5
chr11_+_65787056 0.83 ENST00000335987.8
ovo like transcriptional repressor 1
chr13_+_77741212 0.78 ENST00000441784.5
SLAIN motif family member 1
chr15_+_62758585 0.76 ENST00000472902.1
talin 2
chr15_+_21579912 0.75 ENST00000628444.1
long intergenic non-protein coding RNA 2203
chrX_+_108045050 0.74 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr7_-_73842508 0.71 ENST00000297873.9
methyltransferase like 27
chr15_+_22015233 0.65 ENST00000639059.1
ENST00000640156.1
novel protein
novel transcript
chrX_+_108044967 0.62 ENST00000415430.7
V-set and immunoglobulin domain containing 1
chr7_+_134127299 0.61 ENST00000645682.1
ENST00000285928.2
leucine rich repeats and guanylate kinase domain containing
chr1_+_160400543 0.61 ENST00000368061.3
VANGL planar cell polarity protein 2
chr11_-_72112750 0.59 ENST00000545680.5
ENST00000543587.5
ENST00000538393.5
ENST00000535234.5
ENST00000227618.8
ENST00000535503.5
anaphase promoting complex subunit 15
chr11_-_102780620 0.56 ENST00000279441.9
ENST00000539681.1
matrix metallopeptidase 10
chr7_+_37683817 0.55 ENST00000476620.1
ependymin related 1
chr4_-_149815826 0.53 ENST00000636793.2
ENST00000636414.1
IQ motif containing M
chr6_-_110179855 0.53 ENST00000368938.5
WASP family member 1
chr5_+_177384430 0.51 ENST00000512593.5
ENST00000324417.6
solute carrier family 34 member 1
chrX_+_54920796 0.51 ENST00000442098.5
ENST00000430420.5
ENST00000453081.5
ENST00000319167.12
ENST00000622017.4
ENST00000375022.8
ENST00000399736.5
ENST00000440072.5
ENST00000173898.12
ENST00000431115.5
ENST00000440759.5
ENST00000375041.6
trophinin
chr8_+_54616057 0.49 ENST00000637698.1
RP1 axonemal microtubule associated
chr20_+_9514562 0.47 ENST00000246070.3
lysosomal associated membrane protein family member 5
chr7_-_81770039 0.45 ENST00000222390.11
ENST00000453411.6
ENST00000457544.7
ENST00000444829.7
hepatocyte growth factor
chr11_-_72112068 0.44 ENST00000537644.5
ENST00000538919.5
ENST00000539395.1
ENST00000542531.5
anaphase promoting complex subunit 15
chr2_+_190356514 0.44 ENST00000409027.1
ENST00000458193.1
inositol polyphosphate-1-phosphatase
chr6_+_130421086 0.43 ENST00000545622.5
transmembrane protein 200A
chr12_+_28257195 0.43 ENST00000381259.5
coiled-coil domain containing 91
chr2_+_186506713 0.42 ENST00000445547.1
zinc finger CCCH-type containing 15
chr11_-_72112669 0.41 ENST00000545944.5
ENST00000502597.2
anaphase promoting complex subunit 15
chr8_-_48921419 0.41 ENST00000020945.4
snail family transcriptional repressor 2
chr9_+_121567057 0.41 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2 interacting protein
chr12_+_15546344 0.40 ENST00000674388.1
ENST00000542557.5
ENST00000445537.6
ENST00000544244.5
ENST00000442921.7
protein tyrosine phosphatase receptor type O
chr1_-_111488795 0.39 ENST00000472933.2
transmembrane and immunoglobulin domain containing 3
chr3_+_158801926 0.34 ENST00000622669.4
ENST00000392813.8
ENST00000415822.8
ENST00000651862.1
ENST00000264266.12
major facilitator superfamily domain containing 1
chr7_-_81770013 0.31 ENST00000465234.2
hepatocyte growth factor
chr4_+_85827745 0.31 ENST00000509300.5
Rho GTPase activating protein 24
chr3_-_151316795 0.30 ENST00000260843.5
G protein-coupled receptor 87
chr7_-_100119840 0.28 ENST00000437822.6
TATA-box binding protein associated factor 6
chr16_+_53099100 0.27 ENST00000565832.5
chromodomain helicase DNA binding protein 9
chr13_+_35476740 0.26 ENST00000537702.5
neurobeachin
chr15_-_37101205 0.25 ENST00000338564.9
ENST00000558313.5
ENST00000340545.9
Meis homeobox 2
chr7_-_100119323 0.24 ENST00000523306.5
ENST00000344095.8
ENST00000417349.5
ENST00000493322.5
ENST00000520135.5
ENST00000460673.2
ENST00000453269.7
ENST00000452041.5
ENST00000452438.6
ENST00000451699.5
TATA-box binding protein associated factor 6
chr4_+_112647059 0.23 ENST00000511529.1
La ribonucleoprotein 7, transcriptional regulator
chr5_-_97142753 0.23 ENST00000512378.1
limb and CNS expressed 1
chr4_-_145180496 0.22 ENST00000447906.8
OTU deubiquitinase 4
chr11_-_95923763 0.22 ENST00000497683.6
ENST00000470293.6
ENST00000674968.1
ENST00000484818.6
ENST00000675454.1
ENST00000675981.1
ENST00000674924.1
ENST00000676166.1
ENST00000676440.1
ENST00000675807.1
ENST00000495134.6
ENST00000675196.1
myotubularin related protein 2
chr7_-_100119317 0.22 ENST00000440225.5
TATA-box binding protein associated factor 6
chr4_+_85827891 0.22 ENST00000514229.5
Rho GTPase activating protein 24
chr15_+_58410543 0.22 ENST00000356113.10
ENST00000414170.7
lipase C, hepatic type
chr19_+_54137740 0.21 ENST00000644245.1
ENST00000646002.1
ENST00000221232.11
ENST00000440571.6
ENST00000617930.2
CCR4-NOT transcription complex subunit 3
chr10_+_27532521 0.21 ENST00000683924.1
RAB18, member RAS oncogene family
chr5_+_64505981 0.21 ENST00000334025.3
regulator of G protein signaling 7 binding protein
chr7_+_6615576 0.20 ENST00000457543.4
zinc finger protein 853
chr10_+_97446194 0.18 ENST00000370846.8
ENST00000352634.8
ENST00000353979.7
ENST00000370842.6
ENST00000345745.9
zinc finger DHHC-type palmitoyltransferase 16
chr1_-_224437028 0.17 ENST00000445239.1
WD repeat domain 26
chr7_-_81770122 0.16 ENST00000423064.7
hepatocyte growth factor
chr5_-_20575850 0.15 ENST00000507958.5
cadherin 18
chr11_-_95924067 0.13 ENST00000676027.1
ENST00000675489.1
ENST00000409459.5
ENST00000676261.1
ENST00000352297.11
ENST00000346299.10
ENST00000676272.1
ENST00000393223.8
ENST00000675022.1
ENST00000675362.1
ENST00000675174.1
ENST00000674989.1
ENST00000675848.1
ENST00000675652.1
ENST00000481642.6
myotubularin related protein 2
chr19_-_3557563 0.12 ENST00000389395.7
ENST00000355415.7
major facilitator superfamily domain containing 12
chr6_+_130018565 0.11 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr1_-_151459471 0.11 ENST00000271715.7
pogo transposable element derived with ZNF domain
chr3_-_99850976 0.09 ENST00000487087.5
filamin A interacting protein 1 like
chr10_+_97446137 0.09 ENST00000370854.7
ENST00000393760.6
ENST00000414567.5
zinc finger DHHC-type palmitoyltransferase 16
chr12_+_64404338 0.08 ENST00000332707.10
exportin for tRNA
chr20_-_51802433 0.08 ENST00000395997.3
spalt like transcription factor 4
chr5_-_22853320 0.08 ENST00000504376.6
ENST00000382254.6
cadherin 12
chr8_+_54616078 0.08 ENST00000220676.2
RP1 axonemal microtubule associated
chr1_-_151459198 0.08 ENST00000531094.5
pogo transposable element derived with ZNF domain
chr15_-_55270874 0.08 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A, member RAS oncogene family
chr8_-_48921735 0.08 ENST00000396822.6
snail family transcriptional repressor 2
chr7_+_100119607 0.05 ENST00000262932.5
canopy FGF signaling regulator 4
chr22_+_24555981 0.05 ENST00000215829.8
ENST00000402849.5
small nuclear ribonucleoprotein D3 polypeptide
chr17_-_40799939 0.05 ENST00000306658.8
keratin 28
chr18_+_36129444 0.04 ENST00000543127.5
elongator acetyltransferase complex subunit 2
chr22_-_28094135 0.03 ENST00000442232.1
tetratricopeptide repeat domain 28
chr12_-_118359105 0.03 ENST00000541186.5
ENST00000539872.5
TAO kinase 3
chr1_-_151459169 0.02 ENST00000368863.6
ENST00000409503.5
ENST00000491586.5
ENST00000533351.5
pogo transposable element derived with ZNF domain
chr7_-_81769971 0.01 ENST00000354224.10
ENST00000643024.1
hepatocyte growth factor

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.4 1.2 GO:1902688 regulation of NAD metabolic process(GO:1902688)
0.2 0.5 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.2 0.8 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.2 2.9 GO:0019532 oxalate transport(GO:0019532)
0.2 0.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 0.6 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 1.6 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 10.1 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.9 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 1.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.9 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 1.4 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 1.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.4 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 1.4 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 1.6 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0060187 cell pole(GO:0060187)
0.1 3.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.6 GO:0031209 SCAR complex(GO:0031209)
0.1 0.6 GO:0002177 manchette(GO:0002177)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 10.1 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0061714 folic acid receptor activity(GO:0061714)
0.2 2.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.4 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.5 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.0 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 1.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 9.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling