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Illumina Body Map 2 (GSE30611)

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Results for HOXD10

Z-value: 1.24

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Transcription factors associated with HOXD10

Gene Symbol Gene ID Gene Info
ENSG00000128710.6 homeobox D10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD10hg38_v1_chr2_+_176116768_176116794-0.067.6e-01Click!

Activity profile of HOXD10 motif

Sorted Z-values of HOXD10 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_186717348 5.71 ENST00000447445.1
ENST00000287611.8
ENST00000644859.2
kininogen 1
chr4_+_154563003 4.04 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr2_+_167248638 4.04 ENST00000295237.10
xin actin binding repeat containing 2
chr1_-_237945275 3.96 ENST00000604646.1
MT-RNR2 like 11
chr9_-_101435760 2.93 ENST00000647789.2
ENST00000616752.1
aldolase, fructose-bisphosphate B
chr4_-_71784046 2.52 ENST00000513476.5
ENST00000273951.13
GC vitamin D binding protein
chr12_+_20810698 2.52 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr4_+_119135825 2.51 ENST00000307128.6
myozenin 2
chr3_+_109136707 1.90 ENST00000622536.6
chromosome 3 open reading frame 85
chr6_+_160702238 1.85 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
plasminogen
chr6_-_130222813 1.75 ENST00000437477.6
ENST00000439090.7
sterile alpha motif domain containing 3
chr1_+_207104226 1.72 ENST00000367070.8
complement component 4 binding protein alpha
chr4_+_99574812 1.71 ENST00000422897.6
ENST00000265517.10
microsomal triglyceride transfer protein
chr12_-_9999176 1.69 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chr4_-_76023489 1.64 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr17_+_19533818 1.61 ENST00000436810.6
ENST00000270570.8
ENST00000575023.5
ENST00000395585.5
solute carrier family 47 member 1
chr19_-_47886308 1.59 ENST00000222002.4
sulfotransferase family 2A member 1
chr6_-_132734692 1.55 ENST00000509351.5
ENST00000417437.6
ENST00000423615.6
ENST00000427187.6
ENST00000414302.7
ENST00000367927.9
ENST00000450865.2
vanin 3
chr5_+_157180816 1.50 ENST00000422843.8
IL2 inducible T cell kinase
chr14_+_22304051 1.48 ENST00000390466.1
T cell receptor alpha variable 39
chr4_+_40196907 1.45 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chr1_-_89270751 1.38 ENST00000370459.7
guanylate binding protein 5
chr15_+_48206286 1.35 ENST00000396577.7
ENST00000380993.8
solute carrier family 12 member 1
chr13_+_75804169 1.35 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr5_-_135954962 1.30 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
leukocyte cell derived chemotaxin 2
chr4_+_186227501 1.30 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
kallikrein B1
chr4_-_23881282 1.29 ENST00000613098.4
PPARG coactivator 1 alpha
chr7_+_138076453 1.29 ENST00000242375.8
ENST00000411726.6
aldo-keto reductase family 1 member D1
chr11_+_22668101 1.28 ENST00000630668.2
ENST00000278187.7
growth arrest specific 2
chr7_+_116811048 1.27 ENST00000464223.5
ENST00000484325.1
capping actin protein of muscle Z-line subunit alpha 2
chr6_-_32668368 1.20 ENST00000399084.5
major histocompatibility complex, class II, DQ beta 1
chr7_-_113919000 1.19 ENST00000284601.4
protein phosphatase 1 regulatory subunit 3A
chr1_+_207104287 1.18 ENST00000421786.5
complement component 4 binding protein alpha
chr20_-_36646146 1.15 ENST00000262866.9
Src like adaptor 2
chr1_-_111200633 1.13 ENST00000357640.9
DENN domain containing 2D
chr11_-_93537903 1.12 ENST00000527149.5
single-pass membrane protein with coiled-coil domains 4
chr1_+_109466527 1.11 ENST00000369872.4
synaptophysin like 2
chr16_+_21612637 1.09 ENST00000568826.1
methyltransferase like 9
chr1_+_198638457 1.09 ENST00000367379.6
protein tyrosine phosphatase receptor type C
chr10_-_103153609 1.09 ENST00000675985.1
5'-nucleotidase, cytosolic II
chr5_-_56233287 1.09 ENST00000513241.2
ENST00000341048.9
ankyrin repeat domain 55
chr13_-_46211841 1.06 ENST00000442275.1
lymphocyte cytosolic protein 1
chr11_-_13495984 1.05 ENST00000282091.6
parathyroid hormone
chr3_-_190862688 1.05 ENST00000442080.6
geminin coiled-coil domain containing
chr7_+_138076422 1.05 ENST00000432161.5
aldo-keto reductase family 1 member D1
chr11_-_14972273 1.04 ENST00000396372.2
ENST00000361010.7
ENST00000331587.9
calcitonin related polypeptide alpha
chr16_-_84617547 1.04 ENST00000567786.2
coactosin like F-actin binding protein 1
chr8_-_65789084 1.03 ENST00000379419.8
phosphodiesterase 7A
chr6_-_32530268 1.02 ENST00000374975.4
major histocompatibility complex, class II, DR beta 5
chr1_-_229434086 0.99 ENST00000366684.7
ENST00000684723.1
ENST00000366683.4
actin alpha 1, skeletal muscle
chr2_+_90234809 0.96 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr6_+_10585748 0.94 ENST00000265012.5
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr18_+_3252208 0.93 ENST00000578562.6
myosin light chain 12A
chr6_-_134318097 0.93 ENST00000367858.10
ENST00000533224.1
serum/glucocorticoid regulated kinase 1
chr13_+_75804221 0.93 ENST00000489941.6
ENST00000525373.5
LIM domain 7
chr4_+_85827745 0.92 ENST00000509300.5
Rho GTPase activating protein 24
chr4_+_40197023 0.92 ENST00000381799.10
ras homolog family member H
chr11_-_13496018 0.91 ENST00000529816.1
parathyroid hormone
chr11_+_7088991 0.88 ENST00000306904.7
RBMX like 2
chr11_+_60455839 0.88 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
membrane spanning 4-domains A1
chr15_+_58410543 0.88 ENST00000356113.10
ENST00000414170.7
lipase C, hepatic type
chr11_-_26572102 0.87 ENST00000455601.6
mucin 15, cell surface associated
chr13_-_75366973 0.85 ENST00000648194.1
TBC1 domain family member 4
chr4_-_76007501 0.84 ENST00000264888.6
C-X-C motif chemokine ligand 9
chr17_-_10549612 0.84 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
myosin heavy chain 2
chr2_+_233681877 0.83 ENST00000373426.4
UDP glucuronosyltransferase family 1 member A7
chr3_+_171843337 0.82 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
transmembrane protein 212
chr14_-_22823386 0.82 ENST00000554741.5
solute carrier family 7 member 7
chr1_-_107688492 0.81 ENST00000415432.6
vav guanine nucleotide exchange factor 3
chr6_-_132763424 0.81 ENST00000532012.1
ENST00000525270.5
ENST00000530536.5
ENST00000524919.5
vanin 2
chr17_-_10549652 0.81 ENST00000245503.10
myosin heavy chain 2
chr13_+_75804270 0.80 ENST00000447038.5
LIM domain 7
chr14_+_21918161 0.80 ENST00000390439.2
T cell receptor alpha variable 13-2
chr7_-_122702912 0.79 ENST00000447240.1
ENST00000434824.2
ring finger protein 148
chr17_-_10549694 0.78 ENST00000622564.4
myosin heavy chain 2
chr15_-_55270280 0.78 ENST00000564609.5
RAB27A, member RAS oncogene family
chr10_-_73408313 0.78 ENST00000394847.3
annexin A7
chr3_+_108822759 0.77 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chrX_+_37780049 0.77 ENST00000378588.5
cytochrome b-245 beta chain
chr3_+_46370854 0.76 ENST00000292303.4
C-C motif chemokine receptor 5
chr10_+_94683722 0.76 ENST00000285979.11
cytochrome P450 family 2 subfamily C member 18
chr12_+_8913875 0.76 ENST00000538657.5
polyhomeotic homolog 1
chr3_+_101827982 0.76 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKB inhibitor zeta
chr18_-_28036585 0.75 ENST00000399380.7
cadherin 2
chr1_+_198638968 0.75 ENST00000348564.11
ENST00000530727.5
ENST00000442510.8
ENST00000645247.1
ENST00000367367.8
ENST00000367364.5
ENST00000413409.6
protein tyrosine phosphatase receptor type C
chr4_+_99511008 0.75 ENST00000514652.5
ENST00000326581.9
chromosome 4 open reading frame 17
chr15_+_76336755 0.75 ENST00000290759.9
ISL LIM homeobox 2
chrX_+_12906612 0.75 ENST00000218032.7
toll like receptor 8
chr7_+_142560423 0.75 ENST00000620569.1
T cell receptor beta variable 12-3
chr8_+_54616057 0.74 ENST00000637698.1
RP1 axonemal microtubule associated
chr1_+_40247926 0.74 ENST00000372766.4
transmembrane and coiled-coil domains 2
chrX_-_15315615 0.74 ENST00000380470.7
ENST00000480796.6
ankyrin repeat and SOCS box containing 11
chr1_-_92486916 0.74 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr2_+_87338511 0.73 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr7_+_77840122 0.73 ENST00000450574.5
ENST00000248550.7
putative homeodomain transcription factor 2
chr11_-_59212869 0.73 ENST00000361050.4
macrophage expressed 1
chr18_+_3252267 0.72 ENST00000536605.1
ENST00000580887.5
myosin light chain 12A
chr20_+_59163810 0.72 ENST00000371030.4
zinc finger protein 831
chr12_-_13095798 0.72 ENST00000396302.7
germ cell associated 1
chr6_-_25830557 0.71 ENST00000468082.1
solute carrier family 17 member 1
chr12_+_18738102 0.71 ENST00000317658.5
capping actin protein of muscle Z-line subunit alpha 3
chr9_-_101383558 0.70 ENST00000674556.1
bile acid-CoA:amino acid N-acyltransferase
chr15_+_42274185 0.70 ENST00000440615.6
ENST00000318010.12
glucosidase alpha, neutral C
chr3_-_194398354 0.70 ENST00000401815.1
glycoprotein V platelet
chr10_+_94683771 0.69 ENST00000339022.6
cytochrome P450 family 2 subfamily C member 18
chr6_-_25042003 0.69 ENST00000510784.8
RHO family interacting cell polarization regulator 2
chr1_+_198638723 0.69 ENST00000643513.1
protein tyrosine phosphatase receptor type C
chr3_+_108822778 0.68 ENST00000295756.11
T cell receptor associated transmembrane adaptor 1
chr12_-_13095628 0.67 ENST00000457134.6
ENST00000537302.5
germ cell associated 1
chr6_+_25754699 0.66 ENST00000439485.6
ENST00000377905.9
solute carrier family 17 member 4
chr10_+_94762673 0.66 ENST00000480405.2
ENST00000371321.9
cytochrome P450 family 2 subfamily C member 19
chr11_-_18236795 0.66 ENST00000278222.7
serum amyloid A4, constitutive
chr12_+_21372899 0.65 ENST00000240652.8
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chr12_-_118359105 0.65 ENST00000541186.5
ENST00000539872.5
TAO kinase 3
chr12_+_55362975 0.65 ENST00000641576.1
olfactory receptor family 6 subfamily C member 75
chr4_-_40475749 0.65 ENST00000507180.5
RNA binding motif protein 47
chr18_+_63897152 0.64 ENST00000397996.6
ENST00000418725.1
serpin family B member 10
chr16_-_46763237 0.64 ENST00000536476.5
myosin light chain kinase 3
chr18_-_2982873 0.64 ENST00000584915.1
lipin 2
chr12_+_28452493 0.64 ENST00000542801.5
coiled-coil domain containing 91
chr1_+_236395394 0.63 ENST00000359362.6
EDAR associated death domain
chr2_+_119679184 0.63 ENST00000445518.1
ENST00000272521.7
ENST00000409951.1
transmembrane protein 177
chr12_-_18738006 0.63 ENST00000266505.12
ENST00000543242.5
ENST00000539072.5
ENST00000541966.5
ENST00000648272.1
phospholipase C zeta 1
chr15_+_41256907 0.63 ENST00000560965.1
calcineurin like EF-hand protein 1
chr1_+_180230257 0.63 ENST00000263726.4
LIM homeobox 4
chr13_-_40982880 0.62 ENST00000635415.1
E74 like ETS transcription factor 1
chr2_-_196176320 0.62 ENST00000420683.1
serine/threonine kinase 17b
chr4_-_44651619 0.62 ENST00000415895.9
ENST00000332990.6
Yip1 domain family member 7
chr16_-_47459130 0.62 ENST00000565940.6
integrin alpha FG-GAP repeat containing 1
chr3_+_63967738 0.62 ENST00000484332.1
ataxin 7
chr1_+_192158448 0.62 ENST00000367460.4
regulator of G protein signaling 18
chr3_-_190449782 0.61 ENST00000354905.3
transmembrane protein 207
chr11_-_30586866 0.61 ENST00000528686.2
metallophosphoesterase domain containing 2
chr14_+_76310708 0.60 ENST00000512784.6
estrogen related receptor beta
chr3_-_108953870 0.60 ENST00000261047.8
guanylate cyclase activator 1C
chr6_+_26224192 0.59 ENST00000634733.1
H3 clustered histone 6
chrX_+_12906639 0.59 ENST00000311912.5
toll like receptor 8
chr15_+_94297939 0.59 ENST00000357742.9
multiple C2 and transmembrane domain containing 2
chr1_+_241532370 0.59 ENST00000366559.9
ENST00000366557.8
kynurenine 3-monooxygenase
chr5_-_50441244 0.58 ENST00000303221.10
embigin
chr12_-_13095664 0.58 ENST00000337630.10
ENST00000545699.1
germ cell associated 1
chr4_-_69860138 0.57 ENST00000226444.4
sulfotransferase family 1E member 1
chr6_-_135054848 0.57 ENST00000525067.1
ENST00000367822.9
HBS1 like translational GTPase
chr6_-_36547400 0.57 ENST00000229812.8
serine/threonine kinase 38
chr20_+_63738270 0.57 ENST00000467211.1
novel transcript, LIME1-SLC2A4RG readthrough
chr7_-_115968302 0.57 ENST00000457268.5
transcription factor EC
chr18_+_22914115 0.56 ENST00000579124.5
ENST00000577588.5
ENST00000582354.5
ENST00000581819.5
RB binding protein 8, endonuclease
chr11_+_121102666 0.56 ENST00000264037.2
tectorin alpha
chr9_-_110337808 0.56 ENST00000374510.8
ENST00000374507.4
ENST00000423740.7
ENST00000374511.7
thioredoxin domain containing 8
chr1_-_197067234 0.55 ENST00000367412.2
coagulation factor XIII B chain
chr4_-_83114715 0.55 ENST00000426923.2
ENST00000311507.9
ENST00000509973.5
placenta associated 8
chr3_+_123067016 0.55 ENST00000316218.12
protein disulfide isomerase family A member 5
chr15_+_36594868 0.55 ENST00000566807.5
ENST00000643612.1
ENST00000567389.5
ENST00000562877.5
CDAN1 interacting nuclease 1
chr2_+_68734861 0.55 ENST00000467265.5
Rho GTPase activating protein 25
chr5_+_122129533 0.54 ENST00000296600.5
ENST00000504912.1
ENST00000505843.1
zinc finger protein 474
chr4_-_67963441 0.54 ENST00000508048.6
transmembrane serine protease 11A
chr7_+_90469634 0.54 ENST00000509356.2
PTTG1IP family member 2
chr1_+_61952283 0.53 ENST00000307297.8
PATJ crumbs cell polarity complex component
chr7_+_92057602 0.53 ENST00000491695.2
A-kinase anchoring protein 9
chr10_-_75109085 0.53 ENST00000607131.5
dual specificity phosphatase 13
chrX_-_50200988 0.53 ENST00000358526.7
A-kinase anchoring protein 4
chr12_+_53994874 0.53 ENST00000509328.1
homeobox C6
chr2_-_89085787 0.52 ENST00000390252.2
immunoglobulin kappa variable 3-15
chr6_-_134317905 0.52 ENST00000461976.2
serum/glucocorticoid regulated kinase 1
chr6_-_49964160 0.52 ENST00000322066.4
defensin beta 114
chr11_+_112176364 0.52 ENST00000526088.5
ENST00000532593.5
ENST00000531169.5
beta-carotene oxygenase 2
chr20_-_17558811 0.51 ENST00000536626.7
ENST00000377868.6
beaded filament structural protein 1
chr7_+_106865474 0.51 ENST00000359195.3
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr7_+_138076475 0.51 ENST00000438242.1
aldo-keto reductase family 1 member D1
chr5_-_50441350 0.50 ENST00000508934.5
embigin
chr17_+_42773442 0.50 ENST00000253794.7
ENST00000590339.5
ENST00000589520.1
vacuolar protein sorting 25 homolog
chr6_-_118710065 0.49 ENST00000392500.7
ENST00000368488.9
ENST00000434604.5
centrosomal protein 85 like
chr8_+_54616078 0.48 ENST00000220676.2
RP1 axonemal microtubule associated
chr11_+_112175526 0.48 ENST00000532612.5
ENST00000438022.5
beta-carotene oxygenase 2
chr1_-_75932392 0.48 ENST00000284142.7
ankyrin repeat and SOCS box containing 17
chr5_-_147906530 0.47 ENST00000318315.5
ENST00000515291.1
chromosome 5 open reading frame 46
chr7_-_23347704 0.47 ENST00000619562.4
insulin like growth factor 2 mRNA binding protein 3
chr2_+_68734773 0.47 ENST00000409202.8
Rho GTPase activating protein 25
chr5_+_140875299 0.47 ENST00000613593.1
ENST00000398631.3
protocadherin alpha 12
chr21_-_30216047 0.47 ENST00000399899.2
claudin 8
chr2_+_218710931 0.46 ENST00000442769.5
ENST00000424644.1
tubulin tyrosine ligase like 4
chr14_+_22096017 0.46 ENST00000390452.2
T cell receptor delta variable 1
chr7_+_130207847 0.46 ENST00000297819.4
serine rich single-pass membrane protein 1
chr7_+_142554828 0.45 ENST00000611787.1
T cell receptor beta variable 11-3
chr8_-_51809414 0.45 ENST00000356297.5
peroxidasin like
chr11_+_56027654 0.45 ENST00000641320.1
olfactory receptor family 5 subfamily AS member 1
chr7_-_87713287 0.45 ENST00000416177.1
ENST00000265724.8
ENST00000543898.5
ATP binding cassette subfamily B member 1
chrX_-_21758021 0.44 ENST00000646008.1
small muscle protein X-linked
chr2_+_182716227 0.44 ENST00000680258.1
ENST00000680667.1
ENST00000264065.12
ENST00000616986.5
ENST00000679884.1
DnaJ heat shock protein family (Hsp40) member C10
chr12_-_11134644 0.44 ENST00000539585.1
taste 2 receptor member 30
chr7_+_95485934 0.43 ENST00000325885.6
ankyrin repeat and SOCS box containing 4
chr19_-_55038256 0.43 ENST00000417454.5
ENST00000310373.7
ENST00000333884.2
glycoprotein VI platelet
chr1_-_202889099 0.43 ENST00000367262.4
RAB interacting factor
chr4_-_122456725 0.43 ENST00000226730.5
interleukin 2
chrX_+_15749848 0.43 ENST00000479740.5
ENST00000454127.2
carbonic anhydrase 5B
chr2_+_90172802 0.42 ENST00000390277.3
immunoglobulin kappa variable 3D-11
chr15_-_32454902 0.42 ENST00000562377.1
golgin A8 family member O
chr9_-_127755243 0.42 ENST00000629203.2
ENST00000420366.5
SH2 domain containing 3C
chr7_-_38249572 0.42 ENST00000436911.6
T cell receptor gamma constant 2
chr12_+_103965835 0.42 ENST00000266775.13
ENST00000544861.5
thymine DNA glycosylase

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0030573 bile acid catabolic process(GO:0030573)
0.8 3.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.5 2.5 GO:2000473 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.4 1.3 GO:0071250 cellular response to nitrite(GO:0071250) response to nitrite(GO:0080033) glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) response to resveratrol(GO:1904638) cellular response to resveratrol(GO:1904639) positive regulation of progesterone biosynthetic process(GO:2000184)
0.4 2.0 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.3 1.0 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.3 1.0 GO:0046247 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.3 2.9 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.3 3.0 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3 4.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 1.3 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.3 0.8 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2 0.7 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.2 0.7 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.2 6.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.2 0.6 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.2 0.6 GO:0006711 estrogen catabolic process(GO:0006711)
0.2 1.6 GO:0046618 drug export(GO:0046618)
0.2 1.0 GO:0090131 mesenchyme migration(GO:0090131)
0.2 1.4 GO:0032621 interleukin-18 production(GO:0032621)
0.2 0.6 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.1 0.6 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 2.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.8 GO:0051552 flavone metabolic process(GO:0051552)
0.1 2.0 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.4 GO:1903124 regulation of thioredoxin peroxidase activity(GO:1903123) negative regulation of thioredoxin peroxidase activity(GO:1903124) negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation(GO:1903125) Wnt signalosome assembly(GO:1904887) negative regulation of peroxidase activity(GO:2000469)
0.1 0.6 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.5 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 0.4 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 1.7 GO:0034378 chylomicron assembly(GO:0034378)
0.1 1.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 1.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.6 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.9 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.7 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 0.8 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.9 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 0.4 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.5 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1 0.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 1.9 GO:0001778 plasma membrane repair(GO:0001778)
0.1 1.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 1.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.4 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.1 0.7 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 0.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.6 GO:0007343 egg activation(GO:0007343)
0.1 0.6 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.6 GO:0051697 protein delipidation(GO:0051697)
0.1 0.7 GO:0000023 maltose metabolic process(GO:0000023)
0.1 2.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.5 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.8 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 1.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.8 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.8 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.4 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.4 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.1 GO:0035038 female pronucleus assembly(GO:0035038)
0.1 0.7 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 2.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.2 GO:0033320 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.1 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 1.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.1 0.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.4 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 2.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0042779 tRNA 3'-trailer cleavage, endonucleolytic(GO:0034414) tRNA 3'-trailer cleavage(GO:0042779)
0.0 1.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 1.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0035853 chromosome passenger complex localization to spindle midzone(GO:0035853)
0.0 0.3 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.3 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.6 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.5 GO:1903961 positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.6 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.3 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.1 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.5 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 4.0 GO:0003281 ventricular septum development(GO:0003281)
0.0 0.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.0 0.2 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.6 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 1.7 GO:0030220 platelet formation(GO:0030220)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0044107 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 1.1 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 2.4 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.8 GO:0009651 response to salt stress(GO:0009651)
0.0 0.7 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 1.2 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 1.0 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.3 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.7 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.7 GO:0006544 glycine metabolic process(GO:0006544)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 2.9 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.6 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.0 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 2.5 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.8 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.8 GO:0042100 B cell proliferation(GO:0042100)
0.0 0.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097)
0.0 0.2 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.8 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.4 GO:0006999 nuclear pore organization(GO:0006999)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1990844 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.3 4.0 GO:0005577 fibrinogen complex(GO:0005577)
0.3 1.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2 2.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 0.5 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.5 GO:0044307 dendritic branch(GO:0044307)
0.1 0.4 GO:0032473 cytoplasmic side of mitochondrial outer membrane(GO:0032473) caveola neck(GO:0099400)
0.1 2.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 2.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.3 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.1 0.4 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.8 GO:0072487 MSL complex(GO:0072487)
0.1 2.9 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.7 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 12.6 GO:0072562 blood microparticle(GO:0072562)
0.0 1.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 1.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 3.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.8 GO:0016342 catenin complex(GO:0016342)
0.0 1.8 GO:0001772 immunological synapse(GO:0001772)
0.0 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0097169 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.0 7.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290) translation initiation ternary complex(GO:0044207)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.4 GO:0016459 myosin complex(GO:0016459)
0.0 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.5 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.6 2.5 GO:1902271 D3 vitamins binding(GO:1902271)
0.6 1.8 GO:1904854 proteasome core complex binding(GO:1904854)
0.6 2.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.6 2.8 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.5 2.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.5 1.4 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.4 1.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.3 2.5 GO:0051373 FATZ binding(GO:0051373)
0.3 2.2 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.3 1.6 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.3 1.0 GO:0031716 calcitonin receptor binding(GO:0031716)
0.2 0.7 GO:0052815 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.2 0.6 GO:0005139 interleukin-7 receptor binding(GO:0005139)
0.2 0.5 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.1 0.4 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.4 GO:0034211 GTP-dependent protein kinase activity(GO:0034211) peroxidase inhibitor activity(GO:0036479)
0.1 0.4 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.1 1.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 2.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.9 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 2.1 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.7 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.1 3.3 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.6 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 2.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.3 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 1.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 1.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.3 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 2.0 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.2 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.1 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 1.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 0.4 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 4.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 1.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 2.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.1 GO:1990175 EH domain binding(GO:1990175)
0.0 0.2 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 4.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.8 GO:0050664 superoxide-generating NADPH oxidase activity(GO:0016175) oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 0.3 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0019863 IgE binding(GO:0019863)
0.0 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 2.7 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.6 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.9 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 3.6 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 2.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 2.0 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.3 GO:0017022 myosin binding(GO:0017022)
0.0 1.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.0 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 4.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.5 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 2.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.9 PID CD40 PATHWAY CD40/CD40L signaling
0.0 2.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 3.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 2.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 7.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 2.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 3.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 0.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 3.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 2.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 2.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 1.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.9 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 4.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 3.0 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein