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Illumina Body Map 2 (GSE30611)

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Results for HOXD4

Z-value: 1.25

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Transcription factors associated with HOXD4

Gene Symbol Gene ID Gene Info
ENSG00000170166.6 homeobox D4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD4hg38_v1_chr2_+_176151543_1761515590.019.5e-01Click!

Activity profile of HOXD4 motif

Sorted Z-values of HOXD4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_10549612 7.69 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
myosin heavy chain 2
chr17_-_10549652 7.09 ENST00000245503.10
myosin heavy chain 2
chr17_-_10549694 4.80 ENST00000622564.4
myosin heavy chain 2
chr10_+_68109433 3.09 ENST00000613327.4
ENST00000358913.10
ENST00000373675.3
myopalladin
chr10_-_49762335 2.77 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr5_-_151347552 2.36 ENST00000335244.9
ENST00000521967.1
solute carrier family 36 member 2
chr10_-_49762276 2.24 ENST00000374103.9
oxoglutarate dehydrogenase L
chr2_+_167187364 1.99 ENST00000672671.1
xin actin binding repeat containing 2
chr3_+_142623386 1.96 ENST00000337777.7
ENST00000497199.5
plastin 1
chr8_+_78591222 1.95 ENST00000518467.1
cAMP-dependent protein kinase inhibitor alpha
chr4_-_99657820 1.92 ENST00000511828.2
chromosome 4 open reading frame 54
chr4_+_154563003 1.92 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr6_-_87095059 1.80 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr5_+_90899183 1.73 ENST00000640815.1
adhesion G protein-coupled receptor V1
chr12_-_39340963 1.52 ENST00000552961.5
kinesin family member 21A
chr7_-_137343752 1.46 ENST00000393083.2
pleiotrophin
chr2_+_190180930 1.42 ENST00000443551.2
chromosome 2 open reading frame 88
chr2_-_224569782 1.38 ENST00000409096.5
cullin 3
chr11_-_72781858 1.35 ENST00000537947.5
StAR related lipid transfer domain containing 10
chr2_+_190180835 1.31 ENST00000340623.4
chromosome 2 open reading frame 88
chr6_-_136526472 1.25 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr3_+_159069252 1.24 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1 readthrough
chr2_+_233681877 1.22 ENST00000373426.4
UDP glucuronosyltransferase family 1 member A7
chr10_-_29736956 1.21 ENST00000674475.1
supervillin
chr7_+_55365317 1.07 ENST00000254770.3
LanC like 2
chrX_-_23884017 1.06 ENST00000633372.1
apolipoprotein O
chr2_-_182242031 1.05 ENST00000358139.6
phosphodiesterase 1A
chr7_-_29146436 1.04 ENST00000396276.7
carboxypeptidase vitellogenic like
chr7_-_29146527 1.01 ENST00000265394.10
carboxypeptidase vitellogenic like
chr11_-_72781833 1.01 ENST00000535054.1
ENST00000545082.5
StAR related lipid transfer domain containing 10
chr5_-_35047935 0.99 ENST00000510428.1
ENST00000231420.11
alanine--glyoxylate aminotransferase 2
chrX_-_143636094 0.98 ENST00000356928.2
SLIT and NTRK like family member 4
chr8_-_42541042 0.95 ENST00000518717.1
solute carrier family 20 member 2
chr7_-_137343688 0.93 ENST00000348225.7
pleiotrophin
chr11_+_66011994 0.92 ENST00000312134.3
cystatin E/M
chr5_-_59430600 0.89 ENST00000636120.1
phosphodiesterase 4D
chr12_+_28452493 0.89 ENST00000542801.5
coiled-coil domain containing 91
chr10_+_94089067 0.88 ENST00000371375.1
ENST00000675218.1
phospholipase C epsilon 1
chr7_+_77798750 0.86 ENST00000416283.6
ENST00000422959.6
ENST00000307305.12
ENST00000424760.5
putative homeodomain transcription factor 2
chr2_+_27663441 0.85 ENST00000326019.10
ENST00000613058.4
solute carrier family 4 member 1 adaptor protein
chr22_+_41092869 0.85 ENST00000674155.1
E1A binding protein p300
chr15_-_55917129 0.85 ENST00000338963.6
ENST00000508342.5
NEDD4 E3 ubiquitin protein ligase
chr5_+_69415065 0.85 ENST00000647531.1
ENST00000645446.1
ENST00000325631.10
ENST00000454295.6
MARVEL domain containing 2
chr12_-_86256299 0.85 ENST00000552808.6
ENST00000547225.5
MGAT4 family member C
chr2_-_70553638 0.83 ENST00000444975.5
ENST00000445399.5
ENST00000295400.11
ENST00000418333.6
transforming growth factor alpha
chr1_-_17045219 0.82 ENST00000491274.5
succinate dehydrogenase complex iron sulfur subunit B
chr15_-_55917080 0.81 ENST00000506154.1
NEDD4 E3 ubiquitin protein ligase
chr6_-_136526177 0.79 ENST00000617204.4
microtubule associated protein 7
chr3_+_109136707 0.78 ENST00000622536.6
chromosome 3 open reading frame 85
chr3_+_51861604 0.78 ENST00000333127.4
IQ motif containing F2
chr7_+_123848070 0.76 ENST00000476325.5
hyaluronidase 4
chrX_+_37990773 0.75 ENST00000341016.5
H2A.P histone
chr7_-_122699108 0.75 ENST00000340112.3
ring finger protein 133
chr8_-_71361860 0.75 ENST00000303824.11
ENST00000645451.1
EYA transcriptional coactivator and phosphatase 1
chr10_+_70052582 0.75 ENST00000676699.1
macroH2A.2 histone
chr19_-_47886308 0.73 ENST00000222002.4
sulfotransferase family 2A member 1
chr7_+_77798832 0.71 ENST00000415251.6
ENST00000275575.11
putative homeodomain transcription factor 2
chr15_+_21651844 0.68 ENST00000623441.1
olfactory receptor family 4 subfamily N member 4C
chrX_+_38006551 0.67 ENST00000297875.7
synaptotagmin like 5
chr15_-_72228676 0.67 ENST00000561609.5
pyruvate kinase M1/2
chr2_+_170178136 0.66 ENST00000409044.7
ENST00000408978.9
myosin IIIB
chr2_-_158380960 0.65 ENST00000409187.5
coiled-coil domain containing 148
chr22_-_28711931 0.64 ENST00000434810.5
ENST00000456369.5
checkpoint kinase 2
chr8_-_69834970 0.61 ENST00000260126.9
solute carrier organic anion transporter family member 5A1
chr12_-_86256267 0.61 ENST00000620241.4
MGAT4 family member C
chr1_+_182450132 0.61 ENST00000294854.13
regulator of G protein signaling like 1
chr2_+_233917371 0.61 ENST00000324695.9
ENST00000433712.6
transient receptor potential cation channel subfamily M member 8
chr2_-_169573856 0.61 ENST00000453153.7
ENST00000445210.1
FAST kinase domains 1
chr17_-_66229380 0.60 ENST00000205948.11
apolipoprotein H
chr1_-_151006471 0.59 ENST00000493834.2
MINDY lysine 48 deubiquitinase 1
chrX_-_93673558 0.58 ENST00000475430.2
ENST00000373079.4
nucleosome assembly protein 1 like 3
chr14_-_99480831 0.56 ENST00000331768.10
ENST00000630307.2
SET domain containing 3, actin histidine methyltransferase
chrX_+_56563569 0.56 ENST00000338222.7
ubiquilin 2
chr4_+_158210479 0.56 ENST00000504569.5
ENST00000509278.5
ENST00000514558.5
ENST00000503200.5
ENST00000296529.11
transmembrane protein 144
chr6_+_26158115 0.55 ENST00000377777.5
ENST00000289316.2
H2B clustered histone 5
chr7_+_92057602 0.54 ENST00000491695.2
A-kinase anchoring protein 9
chr1_-_247679739 0.53 ENST00000642119.1
olfactory receptor family 13 subfamily G member 1
chr6_+_142147162 0.52 ENST00000452973.6
ENST00000620996.4
ENST00000367621.1
ENST00000367630.9
vesicle trafficking 1
chr3_-_18438678 0.52 ENST00000414509.5
SATB homeobox 1
chr13_+_77741212 0.52 ENST00000441784.5
SLAIN motif family member 1
chr3_-_18438767 0.52 ENST00000454909.6
SATB homeobox 1
chr15_+_36594868 0.52 ENST00000566807.5
ENST00000643612.1
ENST00000567389.5
ENST00000562877.5
CDAN1 interacting nuclease 1
chr20_-_31390580 0.51 ENST00000339144.3
ENST00000376321.4
defensin beta 119
chr3_-_157503574 0.51 ENST00000494677.5
ENST00000468233.5
ventricular zone expressed PH domain containing 1
chr20_-_31390483 0.49 ENST00000376315.2
defensin beta 119
chr5_+_69415190 0.49 ENST00000515844.1
MARVEL domain containing 2
chr11_-_11353241 0.48 ENST00000528848.3
casein kinase 2 alpha 3
chr5_-_55692620 0.47 ENST00000503817.5
ENST00000512595.5
solute carrier family 38 member 9
chr9_-_21368057 0.47 ENST00000449498.2
interferon alpha 13
chr7_+_101817601 0.46 ENST00000292535.12
ENST00000546411.7
ENST00000549414.6
ENST00000550008.6
ENST00000556210.1
cut like homeobox 1
chr12_+_112906777 0.46 ENST00000452357.7
ENST00000445409.7
2'-5'-oligoadenylate synthetase 1
chr16_-_29899532 0.46 ENST00000308713.9
ENST00000617533.5
seizure related 6 homolog like 2
chr19_-_44401575 0.45 ENST00000591679.5
ENST00000544719.6
ENST00000614994.5
ENST00000585868.1
ENST00000588212.1
zinc finger protein 285
novel protein
chr11_-_78079819 0.45 ENST00000534029.5
ENST00000525085.1
ENST00000527806.1
ENST00000528164.1
ENST00000281031.5
ENST00000528251.1
ENST00000530054.1
NADH:ubiquinone oxidoreductase subunit C2
NDUFC2-KCTD14 readthrough
chr12_+_15956585 0.45 ENST00000526530.1
deoxyribose-phosphate aldolase
chr4_-_183320267 0.44 ENST00000323319.7
claudin 22
chr2_+_186590022 0.44 ENST00000261023.8
ENST00000374907.7
integrin subunit alpha V
chr12_-_118190510 0.42 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr7_-_77798359 0.42 ENST00000257663.4
transmembrane protein 60
chr7_+_138460238 0.42 ENST00000343526.9
tripartite motif containing 24
chr1_+_28438104 0.42 ENST00000633167.1
ENST00000373836.4
phosphatase and actin regulator 4
chr10_+_96304392 0.41 ENST00000630152.1
DNA nucleotidylexotransferase
chr9_-_24545866 0.41 ENST00000543880.7
ENST00000418122.1
IZUMO family member 3
chr13_-_23433676 0.41 ENST00000682547.1
ENST00000455470.6
ENST00000382292.9
sacsin molecular chaperone
chr10_-_17129786 0.40 ENST00000377833.10
cubilin
chr3_+_4680617 0.40 ENST00000648212.1
inositol 1,4,5-trisphosphate receptor type 1
chr13_+_77741160 0.40 ENST00000314070.9
ENST00000351546.7
SLAIN motif family member 1
chr18_-_36798482 0.40 ENST00000590258.2
tubulin polyglutamylase complex subunit 2
chr8_+_23288081 0.39 ENST00000265806.12
ENST00000519952.6
ENST00000518840.6
R3H domain and coiled-coil containing 1
chr15_+_45634721 0.39 ENST00000561735.5
sulfide quinone oxidoreductase
chr11_-_129192291 0.39 ENST00000682385.1
Rho GTPase activating protein 32
chr17_-_37542361 0.39 ENST00000614196.1
synergin gamma
chr2_+_182718046 0.39 ENST00000537515.5
DnaJ heat shock protein family (Hsp40) member C10
chr5_+_116032315 0.38 ENST00000601302.3
ADP ribosylation factor like GTPase 14 effector protein like
chr8_-_42843201 0.38 ENST00000529779.1
ENST00000345117.2
ENST00000254250.7
THAP domain containing 1
chr13_-_61415508 0.37 ENST00000409204.4
protocadherin 20
chr18_+_24460655 0.37 ENST00000426880.2
histamine receptor H4
chr14_+_22598224 0.37 ENST00000428304.6
ENST00000542041.1
ENST00000216327.10
abhydrolase domain containing 4, N-acyl phospholipase B
chr1_-_100894649 0.37 ENST00000450240.2
exostosin like glycosyltransferase 2
chr4_-_69639642 0.36 ENST00000604629.6
ENST00000604021.1
UDP glucuronosyltransferase family 2 member A2
chr14_+_19935608 0.36 ENST00000285600.4
olfactory receptor family 4 subfamily K member 1
chr8_-_71362054 0.36 ENST00000340726.8
EYA transcriptional coactivator and phosphatase 1
chr15_-_64093746 0.36 ENST00000557835.5
ENST00000380290.7
ENST00000300030.8
ENST00000559950.1
cytosolic iron-sulfur assembly component 2A
chr1_+_197268222 0.35 ENST00000367400.8
ENST00000638467.1
ENST00000367399.6
crumbs cell polarity complex component 1
chr13_-_23433735 0.35 ENST00000423156.2
ENST00000683210.1
ENST00000682775.1
ENST00000684497.1
ENST00000682944.1
ENST00000683489.1
ENST00000684385.1
ENST00000683680.1
sacsin molecular chaperone
chr11_-_129192198 0.35 ENST00000310343.13
Rho GTPase activating protein 32
chr18_-_21703688 0.34 ENST00000584464.1
ENST00000578270.5
abhydrolase domain containing 3, phospholipase
chr3_+_97821984 0.34 ENST00000389622.7
crystallin beta-gamma domain containing 3
chr11_+_18396823 0.34 ENST00000625635.1
lactate dehydrogenase A
chr19_-_13953302 0.34 ENST00000585607.1
ENST00000538517.6
ENST00000587458.1
ENST00000538371.6
podocan like 1
chr8_+_49909783 0.33 ENST00000518864.5
syntrophin gamma 1
chr11_+_92969651 0.33 ENST00000257068.3
ENST00000528076.1
melatonin receptor 1B
chr5_+_141966820 0.32 ENST00000513019.5
ENST00000394519.5
ENST00000356143.5
ring finger protein 14
chr17_-_42980393 0.32 ENST00000409446.8
ENST00000409399.6
ENST00000421990.7
prostaglandin E synthase 3 like
PTGES3L-AARSD1 readthrough
chr4_+_73481737 0.32 ENST00000226355.5
afamin
chr2_+_223957431 0.32 ENST00000258383.4
mitochondrial ribosomal protein L44
chrX_+_150699208 0.32 ENST00000436701.5
ENST00000438018.5
myotubularin related protein 1
chr7_-_105269007 0.31 ENST00000357311.7
SRSF protein kinase 2
chr15_+_80072559 0.31 ENST00000560228.5
ENST00000559835.5
ENST00000559775.5
ENST00000558688.5
ENST00000560392.5
ENST00000560976.5
ENST00000558272.5
ENST00000558390.5
zinc finger AN1-type containing 6
chr9_-_104536856 0.30 ENST00000641090.1
olfactory receptor family 13 subfamily C member 3
chr20_-_10420737 0.30 ENST00000649912.1
novel protein
chr1_+_210328244 0.30 ENST00000541565.5
ENST00000413764.6
hedgehog acyltransferase
chr2_-_165204042 0.29 ENST00000283254.12
ENST00000453007.1
sodium voltage-gated channel alpha subunit 3
chr8_-_71362119 0.29 ENST00000388741.7
EYA transcriptional coactivator and phosphatase 1
chr4_+_68447453 0.29 ENST00000305363.9
transmembrane serine protease 11E
chr10_+_84425148 0.29 ENST00000493409.5
coiled-coil serine rich protein 2
chr13_+_51339683 0.29 ENST00000419898.2
ENST00000681248.1
serpin family E member 3
chr1_-_246193727 0.29 ENST00000391836.3
SET and MYND domain containing 3
chr1_-_100894775 0.28 ENST00000416479.1
ENST00000370113.7
exostosin like glycosyltransferase 2
chr6_-_50049923 0.28 ENST00000651554.2
defensin beta 112
chr10_+_12129637 0.27 ENST00000379051.5
ENST00000379033.7
ENST00000441368.5
ENST00000298428.14
ENST00000304267.12
ENST00000379020.8
ENST00000379017.7
SEC61 translocon subunit alpha 2
chr11_+_55723776 0.27 ENST00000641440.1
olfactory receptor family 5 subfamily D member 3 pseudogene
chr1_+_197268204 0.27 ENST00000535699.5
ENST00000538660.5
crumbs cell polarity complex component 1
chr4_-_36243939 0.26 ENST00000506189.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_+_141262614 0.26 ENST00000504264.5
2-phosphoxylose phosphatase 1
chr20_+_33562365 0.26 ENST00000346541.7
ENST00000397800.5
ENST00000492345.5
CBFA2/RUNX1 partner transcriptional co-repressor 2
chr12_+_18242955 0.26 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr7_+_112423137 0.26 ENST00000005558.8
ENST00000621379.4
interferon related developmental regulator 1
chr5_+_140841183 0.25 ENST00000378123.4
ENST00000531613.2
protocadherin alpha 8
chr4_+_74308492 0.25 ENST00000502358.5
ENST00000503098.5
ENST00000505212.5
ENST00000509145.5
ENST00000514968.5
epithelial mitogen
chr3_+_69763726 0.25 ENST00000448226.9
melanocyte inducing transcription factor
chr20_-_47351877 0.25 ENST00000446894.5
zinc finger MYND-type containing 8
chrX_+_49879475 0.25 ENST00000621775.2
ubiquitin specific peptidase 27 X-linked
chr9_-_94640130 0.25 ENST00000414122.1
fructose-bisphosphatase 1
chr2_+_108621260 0.25 ENST00000409441.5
LIM zinc finger domain containing 1
chr15_+_64094060 0.24 ENST00000560829.5
sorting nexin 1
chr4_-_39977836 0.23 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr12_+_14365661 0.23 ENST00000261168.9
ENST00000538511.5
ENST00000545723.1
ENST00000543189.5
activating transcription factor 7 interacting protein
chr9_-_125484490 0.23 ENST00000444226.1
MAPK associated protein 1
chr6_+_122996227 0.23 ENST00000275162.10
clavesin 2
chr11_+_124256376 0.22 ENST00000641992.2
olfactory receptor family 8 subfamily G member 5
chr9_+_470291 0.22 ENST00000382303.5
KN motif and ankyrin repeat domains 1
chr2_+_32277883 0.22 ENST00000238831.9
Yip1 domain family member 4
chr14_+_60982358 0.22 ENST00000526105.5
solute carrier family 38 member 6
chr21_-_29061351 0.22 ENST00000432178.5
chaperonin containing TCP1 subunit 8
chr17_-_40782544 0.22 ENST00000301656.4
keratin 27
chr13_+_23570370 0.22 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr11_-_16397521 0.21 ENST00000533411.5
SRY-box transcription factor 6
chr2_+_71453538 0.21 ENST00000258104.8
dysferlin
chr6_-_49744378 0.21 ENST00000371159.8
ENST00000263045.9
cysteine rich secretory protein 3
chr1_-_100894818 0.21 ENST00000370114.8
exostosin like glycosyltransferase 2
chr5_-_139198358 0.21 ENST00000394817.7
SIL1 nucleotide exchange factor
chr3_-_180989678 0.21 ENST00000491873.5
ENST00000382564.8
ENST00000486355.1
DnaJ heat shock protein family (Hsp40) member C19
chr16_-_2329687 0.20 ENST00000567910.1
ATP binding cassette subfamily A member 3
chr1_-_28058087 0.20 ENST00000373864.5
EYA transcriptional coactivator and phosphatase 3
chr4_-_84966637 0.20 ENST00000295888.9
WD repeat and FYVE domain containing 3
chr4_+_129093682 0.20 ENST00000502887.5
chromosome 4 open reading frame 33
chr6_+_46793379 0.19 ENST00000230588.9
ENST00000611727.2
meprin A subunit alpha
chr5_-_55692731 0.19 ENST00000502247.1
solute carrier family 38 member 9
chr15_+_92900189 0.19 ENST00000626874.2
ENST00000627622.1
ENST00000629346.2
ENST00000628375.2
ENST00000420239.7
ENST00000394196.9
chromodomain helicase DNA binding protein 2
chr2_+_165239388 0.17 ENST00000424833.5
ENST00000375437.7
ENST00000631182.3
sodium voltage-gated channel alpha subunit 2
chr6_-_26108125 0.17 ENST00000338379.6
H1.6 linker histone, cluster member
chr6_-_49744434 0.16 ENST00000433368.6
ENST00000354620.4
cysteine rich secretory protein 3
chr2_-_213151590 0.15 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chr12_-_48852153 0.15 ENST00000308025.8
DEAD-box helicase 23
chr5_-_177780633 0.15 ENST00000513554.5
ENST00000440605.7
family with sequence similarity 153 member A
chr2_-_162838728 0.15 ENST00000328032.8
ENST00000332142.10
potassium voltage-gated channel subfamily H member 7
chr22_-_28712136 0.14 ENST00000464581.6
checkpoint kinase 2
chr18_+_63702958 0.14 ENST00000544088.6
serpin family B member 11
chr5_-_56116946 0.14 ENST00000434982.2
ankyrin repeat domain 55

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 19.8 GO:0001778 plasma membrane repair(GO:0001778)
0.8 2.4 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.6 1.7 GO:0051821 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.4 2.0 GO:1902896 terminal web assembly(GO:1902896)
0.3 1.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.3 1.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.3 0.8 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 1.0 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.2 2.4 GO:0015808 L-alanine transport(GO:0015808)
0.2 0.6 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.2 1.2 GO:0009804 coumarin metabolic process(GO:0009804)
0.2 0.9 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.4 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.7 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 1.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 2.4 GO:0032782 bile acid secretion(GO:0032782)
0.1 1.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.9 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 5.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.4 GO:0061386 closure of optic fissure(GO:0061386)
0.1 2.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.4 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 2.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.3 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.9 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.6 GO:0050955 thermoception(GO:0050955)
0.1 0.7 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 1.1 GO:0042407 cristae formation(GO:0042407)
0.1 0.4 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.9 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 1.7 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1 1.0 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.2 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 1.0 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 1.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.5 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.2 GO:1903756 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.5 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.1 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.2 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.8 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 1.8 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.4 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0035724 CD24 biosynthetic process(GO:0035724) activation of meiosis involved in egg activation(GO:0060466) negative regulation of monocyte extravasation(GO:2000438) regulation of CD24 biosynthetic process(GO:2000559) positive regulation of CD24 biosynthetic process(GO:2000560)
0.0 0.8 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.1 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0098942 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.3 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.3 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 2.2 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.2 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.3 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.7 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.6 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 1.2 GO:0003281 ventricular septum development(GO:0003281)
0.0 0.0 GO:0003350 pulmonary myocardium development(GO:0003350)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 19.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.5 5.0 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.3 2.0 GO:1990357 terminal web(GO:1990357)
0.2 0.7 GO:1902912 pyruvate kinase complex(GO:1902912)
0.2 0.8 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 2.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 1.1 GO:0061617 MICOS complex(GO:0061617)
0.1 1.9 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 1.4 GO:0005827 polar microtubule(GO:0005827)
0.1 0.5 GO:0044307 dendritic branch(GO:0044307)
0.1 1.3 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.7 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.8 GO:0070852 cell body fiber(GO:0070852)
0.1 1.2 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 1.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089) chylomicron(GO:0042627)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.4 GO:0031941 filamentous actin(GO:0031941)
0.0 2.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.5 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.6 2.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.4 19.6 GO:0000146 microfilament motor activity(GO:0000146)
0.3 1.4 GO:0031208 POZ domain binding(GO:0031208)
0.2 0.9 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.2 2.4 GO:0022858 hydrogen:amino acid symporter activity(GO:0005280) L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.2 1.7 GO:0050816 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.2 0.8 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.2 1.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.0 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.1 0.3 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.9 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 1.0 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.7 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 0.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.6 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 0.4 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.1 0.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 3.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 2.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 2.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.8 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 2.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 2.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.3 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 1.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0043682 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.8 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.4 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.9 GO:0051087 chaperone binding(GO:0051087)
0.0 0.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.8 GO:0005179 hormone activity(GO:0005179)
0.0 1.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 19.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.9 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 2.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.9 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta