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Illumina Body Map 2 (GSE30611)

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Results for HSF1

Z-value: 1.25

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Transcription factors associated with HSF1

Gene Symbol Gene ID Gene Info
ENSG00000185122.11 heat shock transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF1hg38_v1_chr8_+_144291581_1442916170.477.3e-03Click!

Activity profile of HSF1 motif

Sorted Z-values of HSF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_161524539 4.74 ENST00000309758.6
heat shock protein family A (Hsp70) member 6
chrX_+_147981324 2.94 ENST00000370467.8
FMR1 neighbor
chr3_-_46464868 2.79 ENST00000417439.5
ENST00000231751.9
ENST00000431944.1
lactotransferrin
chr19_+_859654 2.78 ENST00000592860.2
ENST00000327726.11
complement factor D
chr6_+_35297809 2.77 ENST00000316637.7
DEF6 guanine nucleotide exchange factor
chr6_-_31815244 2.71 ENST00000375654.5
heat shock protein family A (Hsp70) member 1 like
chr7_+_80646436 2.61 ENST00000419819.2
CD36 molecule
chr15_+_75198866 2.57 ENST00000562637.1
ENST00000360639.6
chromosome 15 open reading frame 39
chr2_-_89213917 2.53 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr1_-_183569186 2.53 ENST00000420553.5
ENST00000419402.1
neutrophil cytosolic factor 2
chr11_+_1870871 2.43 ENST00000417766.5
lymphocyte specific protein 1
chr5_+_119354771 2.42 ENST00000503646.1
TNF alpha induced protein 8
chr3_+_114294020 2.40 ENST00000383671.8
T cell immunoreceptor with Ig and ITIM domains
chr20_-_45827297 2.39 ENST00000372555.8
troponin C2, fast skeletal type
chr7_+_150567382 2.36 ENST00000255945.4
ENST00000479232.1
GTPase, IMAP family member 4
chr7_+_150567347 2.35 ENST00000461940.5
GTPase, IMAP family member 4
chr7_+_80646305 2.25 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr2_-_89177160 2.16 ENST00000484817.1
immunoglobulin kappa variable 2-24
chr20_+_45174894 2.16 ENST00000243924.4
peptidase inhibitor 3
chr3_+_48223479 2.13 ENST00000652295.2
cathelicidin antimicrobial peptide
chr7_+_80646347 2.09 ENST00000413265.5
CD36 molecule
chr6_+_31815532 2.09 ENST00000375651.7
ENST00000608703.1
heat shock protein family A (Hsp70) member 1A
chr7_+_150737382 2.08 ENST00000358647.5
GTPase, IMAP family member 5
chr14_-_106335613 2.06 ENST00000603660.1
immunoglobulin heavy variable 3-30
chr21_-_42315336 2.03 ENST00000398431.2
ENST00000518498.3
trefoil factor 3
chr11_-_105035113 1.98 ENST00000526568.5
ENST00000531166.5
ENST00000534497.5
ENST00000527979.5
ENST00000533400.6
ENST00000528974.1
ENST00000525825.5
ENST00000353247.9
ENST00000446369.5
ENST00000436863.7
caspase 1
chr18_+_59899988 1.94 ENST00000316660.7
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr1_-_171652675 1.93 ENST00000037502.11
myocilin
chr19_-_2085324 1.89 ENST00000591638.1
MOB kinase activator 3A
chr5_+_170232912 1.88 ENST00000524171.5
ENST00000517575.4
ENST00000518395.2
ENST00000593851.5
chromosome 5 open reading frame 58
chr11_-_19201976 1.83 ENST00000647990.1
ENST00000649235.1
ENST00000265968.9
ENST00000649842.1
cysteine and glycine rich protein 3
chr14_-_24576240 1.80 ENST00000216336.3
cathepsin G
chrX_+_52495791 1.78 ENST00000375602.2
ENST00000375600.5
X antigen family member 1A
chr2_-_191847068 1.76 ENST00000304141.5
caveolae associated protein 2
chr3_+_32391841 1.75 ENST00000334983.10
CKLF like MARVEL transmembrane domain containing 7
chr2_+_28496054 1.75 ENST00000327757.10
ENST00000422425.6
ENST00000404858.5
phospholipase B1
chr20_+_38304149 1.73 ENST00000262865.9
ENST00000642449.2
bactericidal permeability increasing protein
chr4_+_101790717 1.72 ENST00000508653.5
ENST00000322953.9
B cell scaffold protein with ankyrin repeats 1
chr12_+_10307950 1.72 ENST00000543420.5
ENST00000543777.5
killer cell lectin like receptor D1
chr19_-_55325316 1.71 ENST00000591570.5
ENST00000326652.9
transmembrane protein 150B
chr1_+_159302321 1.68 ENST00000368114.1
Fc fragment of IgE receptor Ia
chr1_-_153390976 1.65 ENST00000368732.5
ENST00000368733.4
S100 calcium binding protein A8
chr11_+_60378524 1.63 ENST00000530614.5
ENST00000530027.5
ENST00000300184.8
ENST00000530234.2
ENST00000528215.1
ENST00000531787.5
membrane spanning 4-domains A7
membrane spanning 4-domains A14
chr17_+_47323941 1.62 ENST00000331493.7
ENST00000519772.5
ENST00000517484.5
EF-hand calcium binding domain 13
chr6_+_31827730 1.61 ENST00000375650.5
heat shock protein family A (Hsp70) member 1B
chr17_-_48430205 1.60 ENST00000336915.11
ENST00000584924.5
src kinase associated phosphoprotein 1
chr5_-_172188185 1.60 ENST00000176763.10
serine/threonine kinase 10
chr16_+_28931942 1.58 ENST00000324662.8
ENST00000538922.8
CD19 molecule
chr17_-_41505597 1.52 ENST00000336861.7
ENST00000246635.8
ENST00000587544.5
ENST00000587435.1
keratin 13
chr9_+_89311187 1.52 ENST00000314355.7
CDC28 protein kinase regulatory subunit 2
chr22_-_36160773 1.51 ENST00000531095.1
ENST00000349314.6
ENST00000397293.6
apolipoprotein L3
chr19_-_2051224 1.49 ENST00000309340.11
ENST00000589534.2
ENST00000250896.9
ENST00000589509.5
MAPK interacting serine/threonine kinase 2
chr15_-_60397964 1.49 ENST00000558998.5
ENST00000560165.5
ENST00000557986.5
ENST00000559467.5
ENST00000677968.1
ENST00000678450.1
ENST00000332680.8
ENST00000396024.7
ENST00000557906.6
ENST00000558558.6
ENST00000559113.6
ENST00000559780.6
ENST00000559956.6
ENST00000560468.6
ENST00000678870.1
ENST00000678061.1
ENST00000451270.7
ENST00000421017.6
ENST00000560466.5
ENST00000558132.5
ENST00000559370.5
ENST00000559725.5
ENST00000558985.6
ENST00000679109.1
annexin A2
chr4_-_83109843 1.47 ENST00000411416.6
placenta associated 8
chr17_+_42853232 1.46 ENST00000617500.4
amine oxidase copper containing 3
chr1_+_110873135 1.45 ENST00000271324.6
CD53 molecule
chr17_+_42853265 1.44 ENST00000592999.5
amine oxidase copper containing 3
chr19_-_7702124 1.42 ENST00000597921.6
Fc fragment of IgE receptor II
chr2_+_27051637 1.40 ENST00000451003.5
ENST00000360131.5
ENST00000323064.12
ATP/GTP binding protein like 5
chrX_+_30215551 1.40 ENST00000378988.5
MAGE family member B2
chr14_-_106235582 1.39 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr5_+_150778733 1.37 ENST00000526627.2
small integral membrane protein 3
chr16_+_27066919 1.36 ENST00000505035.3
chromosome 16 open reading frame 82
chr20_+_18813777 1.35 ENST00000377428.4
SCP2 sterol binding domain containing 1
chr4_-_25863537 1.34 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr2_+_90004792 1.34 ENST00000462693.1
immunoglobulin kappa variable 2D-24 (non-functional)
chr2_+_85695368 1.33 ENST00000526018.1
granulysin
chrX_-_52517057 1.33 ENST00000375613.7
X antigen family member 1B
chr11_-_26572102 1.32 ENST00000455601.6
mucin 15, cell surface associated
chr9_-_136748515 1.32 ENST00000341206.9
lipocalin 6
chr14_-_106803221 1.31 ENST00000390636.2
immunoglobulin heavy variable 3-73
chr20_+_46008900 1.30 ENST00000372330.3
matrix metallopeptidase 9
chr1_-_1779976 1.29 ENST00000378625.5
NAD kinase
chr19_-_54364863 1.29 ENST00000348231.8
leukocyte associated immunoglobulin like receptor 1
chr12_-_52517929 1.29 ENST00000548409.5
keratin 5
chr17_-_73227700 1.28 ENST00000579872.1
ENST00000580032.1
family with sequence similarity 104 member A
chr19_-_7702139 1.28 ENST00000346664.9
Fc fragment of IgE receptor II
chr19_-_54364983 1.26 ENST00000434277.6
leukocyte associated immunoglobulin like receptor 1
chrX_+_109536832 1.26 ENST00000372106.6
nuclear transport factor 2 like export factor 2
chr17_+_42851167 1.25 ENST00000613571.1
ENST00000308423.7
amine oxidase copper containing 3
chr3_-_108222383 1.25 ENST00000264538.4
intraflagellar transport 57
chr19_+_48019726 1.24 ENST00000593413.1
epididymal sperm binding protein 1
chr14_-_106117159 1.24 ENST00000390601.3
immunoglobulin heavy variable 3-11
chr5_+_150778781 1.24 ENST00000648745.1
small integral membrane protein 3
chr4_-_48134200 1.24 ENST00000264316.9
TXK tyrosine kinase
chr12_+_10307818 1.23 ENST00000350274.9
ENST00000336164.9
killer cell lectin like receptor D1
chr11_-_26572130 1.22 ENST00000527569.1
mucin 15, cell surface associated
chr3_-_151203201 1.21 ENST00000480322.1
ENST00000309180.6
G protein-coupled receptor 171
chr1_-_108192818 1.20 ENST00000370041.4
solute carrier family 25 member 24
chr7_+_142670734 1.20 ENST00000390398.3
T cell receptor beta variable 25-1
chr1_+_220879434 1.20 ENST00000366903.8
H2.0 like homeobox
chr14_+_75522427 1.19 ENST00000286639.8
basic leucine zipper ATF-like transcription factor
chr19_+_35448251 1.17 ENST00000599180.3
free fatty acid receptor 2
chr14_-_106675544 1.16 ENST00000390632.2
immunoglobulin heavy variable 3-66
chr5_+_74766981 1.15 ENST00000296802.9
NSA2 ribosome biogenesis factor
chr6_-_41941507 1.15 ENST00000372987.8
cyclin D3
chr16_+_68085861 1.14 ENST00000570212.5
ENST00000562926.5
nuclear factor of activated T cells 3
chr11_-_26572254 1.13 ENST00000529533.6
mucin 15, cell surface associated
chr11_+_809961 1.13 ENST00000321153.9
ENST00000530797.5
ribosomal protein lateral stalk subunit P2
chr19_-_54364908 1.12 ENST00000391742.7
leukocyte associated immunoglobulin like receptor 1
chr1_+_156147350 1.12 ENST00000435124.5
ENST00000633494.1
semaphorin 4A
chr17_+_60422483 1.11 ENST00000269127.5
chromosome 17 open reading frame 64
chrX_+_72938163 1.11 ENST00000593662.1
ENST00000611003.2
family with sequence similarity 235 member A
chr14_-_106360320 1.11 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr11_-_19202004 1.11 ENST00000648719.1
cysteine and glycine rich protein 3
chr15_+_81296913 1.11 ENST00000394652.6
interleukin 16
chr9_-_34710069 1.10 ENST00000378792.1
ENST00000259607.7
C-C motif chemokine ligand 21
chr16_+_85908988 1.10 ENST00000566369.1
interferon regulatory factor 8
chr2_+_202634960 1.10 ENST00000392238.3
family with sequence similarity 117 member B
chr19_-_14518383 1.09 ENST00000254322.3
ENST00000595139.2
DnaJ heat shock protein family (Hsp40) member B1
chr5_-_140673568 1.09 ENST00000542735.2
DND microRNA-mediated repression inhibitor 1
chr16_-_3256587 1.09 ENST00000536379.5
ENST00000541159.5
ENST00000339854.8
ENST00000219596.6
MEFV innate immuity regulator, pyrin
chr19_-_344786 1.08 ENST00000264819.7
MIER family member 2
chr16_+_28985251 1.07 ENST00000360872.9
ENST00000566177.5
linker for activation of T cells
chr22_+_43151931 1.07 ENST00000329563.8
ENST00000396265.4
translocator protein
chrX_-_42778155 1.07 ENST00000378131.4
PPP1R2C family member C
chr3_+_189100102 1.07 ENST00000412373.5
tumor protein p63 regulated 1
chr19_-_54364807 1.06 ENST00000474878.5
leukocyte associated immunoglobulin like receptor 1
chr22_-_26565362 1.06 ENST00000398110.6
tyrosylprotein sulfotransferase 2
chr14_-_106088573 1.04 ENST00000632099.1
immunoglobulin heavy variable 3-64D
chr16_+_21158653 1.04 ENST00000572258.5
ENST00000233047.9
ENST00000261388.7
ENST00000451578.6
ENST00000572599.5
ENST00000577162.1
transmembrane protein 159
chr1_-_161307420 1.04 ENST00000491222.5
ENST00000672287.2
myelin protein zero
chr6_-_131628165 1.03 ENST00000368053.8
ENST00000354577.8
ENST00000368060.7
ENST00000368068.8
mediator complex subunit 23
chr15_-_55270874 1.03 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A, member RAS oncogene family
chr22_+_36913620 1.03 ENST00000403662.8
ENST00000262825.9
colony stimulating factor 2 receptor subunit beta
chr1_+_206897435 1.02 ENST00000391929.7
ENST00000294984.7
ENST00000611909.4
ENST00000367093.3
interleukin 24
chr1_+_220786853 1.02 ENST00000366910.10
mitochondrial amidoxime reducing component 1
chr9_+_70043840 1.02 ENST00000377182.5
MAM domain containing 2
chr6_-_32816910 1.02 ENST00000447394.1
ENST00000438763.7
major histocompatibility complex, class II, DO beta
chr1_+_26831992 1.01 ENST00000374141.6
zinc finger DHHC-type palmitoyltransferase 18
chr2_+_231592858 1.00 ENST00000313965.4
testis expressed 44
chrX_-_72305892 1.00 ENST00000450875.5
ENST00000417400.1
ENST00000431381.5
ENST00000445983.5
ENST00000651998.1
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr16_+_1966820 1.00 ENST00000569210.6
ENST00000569714.6
ring finger protein 151
chr5_-_41071314 0.99 ENST00000399564.5
maestro heat like repeat family member 2B
chr14_-_106593319 0.99 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr5_-_43043170 0.98 ENST00000314890.3
annexin A2 receptor
chr17_+_47253817 0.97 ENST00000559488.7
ENST00000571680.1
integrin subunit beta 3
chrX_-_48919015 0.95 ENST00000376509.4
Pim-2 proto-oncogene, serine/threonine kinase
chr19_-_42302766 0.95 ENST00000595530.5
ENST00000538771.5
ENST00000601865.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr1_-_182400660 0.95 ENST00000367565.2
transmembrane epididymal protein 1
chr19_+_47309853 0.95 ENST00000355085.4
complement C5a receptor 1
chr16_+_28985043 0.95 ENST00000395456.7
ENST00000564277.5
ENST00000630764.2
ENST00000354453.7
linker for activation of T cells
chr21_+_41361999 0.95 ENST00000436410.5
ENST00000435611.6
ENST00000330714.8
MX dynamin like GTPase 2
chrX_+_15749848 0.94 ENST00000479740.5
ENST00000454127.2
carbonic anhydrase 5B
chr8_-_56446572 0.94 ENST00000518974.5
ENST00000451791.7
ENST00000523051.5
ENST00000518770.1
proenkephalin
chr12_+_6789508 0.94 ENST00000011653.9
ENST00000541982.5
ENST00000539492.1
CD4 molecule
chr1_-_46616804 0.92 ENST00000531769.6
ENST00000319928.8
MAPK interacting serine/threonine kinase 1
MOB kinase activator 3C
chrX_-_72782660 0.92 ENST00000596535.3
family with sequence similarity 236 member B
chr16_-_58546702 0.92 ENST00000567133.1
CCR4-NOT transcription complex subunit 1
chr14_+_66486356 0.91 ENST00000636229.1
coiled-coil domain containing 196
chr1_-_201421718 0.90 ENST00000367312.5
ENST00000555340.6
ENST00000361379.9
ENST00000622580.4
troponin I1, slow skeletal type
chr19_-_14517425 0.89 ENST00000676577.1
ENST00000677204.1
ENST00000598235.2
DnaJ heat shock protein family (Hsp40) member B1
chr13_-_48444653 0.89 ENST00000378434.8
lysophosphatidic acid receptor 6
chr8_-_56445941 0.88 ENST00000517415.1
ENST00000314922.3
proenkephalin
chr10_-_114684612 0.88 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr1_+_26832013 0.88 ENST00000534643.5
zinc finger DHHC-type palmitoyltransferase 18
chr11_+_60378475 0.87 ENST00000358246.5
membrane spanning 4-domains A7
chr17_-_56833889 0.87 ENST00000397861.7
chromosome 17 open reading frame 67
chr15_+_34345865 0.86 ENST00000333756.4
NUT midline carcinoma family member 1
chr18_-_21704763 0.85 ENST00000580981.5
ENST00000289119.7
abhydrolase domain containing 3, phospholipase
chr16_+_4556335 0.85 ENST00000444310.5
chromosome 16 open reading frame 96
chr1_-_178871022 0.83 ENST00000367629.1
angiopoietin like 1
chrX_-_155334580 0.83 ENST00000369449.7
ENST00000321926.4
chloride intracellular channel 2
chr19_-_17847962 0.82 ENST00000458235.7
ENST00000534444.1
Janus kinase 3
chr21_+_34073569 0.82 ENST00000399312.3
ENST00000381151.5
ENST00000362077.4
mitochondrial ribosomal protein S6
solute carrier family 5 member 3
novel transcript
chr10_+_116324440 0.82 ENST00000333254.4
coiled-coil domain containing 172
chr12_+_99647749 0.81 ENST00000324341.2
family with sequence similarity 71 member C
chr9_-_19033200 0.81 ENST00000380534.9
ENST00000380530.1
stabilizer of axonemal microtubules 1
chr22_+_35381086 0.80 ENST00000216117.9
ENST00000677931.1
ENST00000679074.1
heme oxygenase 1
chr19_-_42217667 0.80 ENST00000336034.8
ENST00000596251.6
ENST00000598200.1
ENST00000598727.5
death effector domain containing 2
chr16_+_28974813 0.80 ENST00000352260.11
sphingolipid transporter 1 (putative)
chr1_+_223393401 0.79 ENST00000366875.5
coiled-coil domain containing 185
chr19_+_48552159 0.79 ENST00000201586.7
sulfotransferase family 2B member 1
chr7_-_117427487 0.78 ENST00000284629.7
ankyrin repeat, SAM and basic leucine zipper domain containing 1
chr1_+_202214072 0.78 ENST00000439764.2
leucine rich repeat containing G protein-coupled receptor 6
chr14_-_24339951 0.78 ENST00000216274.10
receptor interacting serine/threonine kinase 3
chr16_+_28974221 0.77 ENST00000567771.5
ENST00000568388.5
sphingolipid transporter 1 (putative)
chr7_-_112939773 0.77 ENST00000297145.9
base methyltransferase of 25S rRNA 2 homolog
chr1_-_235866916 0.77 ENST00000389794.7
lysosomal trafficking regulator
chr1_-_178871060 0.76 ENST00000234816.7
angiopoietin like 1
chr10_-_5499544 0.76 ENST00000380332.5
calmodulin like 5
chr2_+_189857393 0.76 ENST00000452382.1
PMS1 homolog 1, mismatch repair system component
chr6_-_131628060 0.76 ENST00000539158.1
ENST00000368058.5
mediator complex subunit 23
chr10_-_80356710 0.76 ENST00000454362.5
ENST00000372204.7
ENST00000372202.6
ENST00000453477.1
DPY30 domain containing 1
chr2_+_74206384 0.75 ENST00000678623.1
ENST00000678731.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr4_-_76421121 0.75 ENST00000682701.1
coiled-coil domain containing 158
chr1_-_235866867 0.74 ENST00000389793.7
lysosomal trafficking regulator
chr14_-_93976550 0.74 ENST00000555019.6
ankyrin repeat and SOCS box containing 2
chrX_+_109536641 0.74 ENST00000372107.5
nuclear transport factor 2 like export factor 2
chr2_-_197786238 0.73 ENST00000282278.12
boule homolog, RNA binding protein
chr6_-_49964160 0.73 ENST00000322066.4
defensin beta 114
chr1_-_156295647 0.73 ENST00000362007.6
ENST00000612353.4
ENST00000614643.4
ENST00000622703.4
glycosylated lysosomal membrane protein
chr5_-_176537361 0.73 ENST00000274811.9
ring finger protein 44
chr11_+_59713403 0.73 ENST00000641815.1
syntaxin 3
chr4_+_105895487 0.72 ENST00000506666.5
ENST00000503451.5
nephronectin
chr6_+_152697888 0.72 ENST00000367245.5
ENST00000529453.1
MYC target 1
chr19_-_474880 0.72 ENST00000382696.7
ENST00000315489.5
outer dense fiber of sperm tails 3 like 2
chr15_-_55289756 0.72 ENST00000336787.6
RAB27A, member RAS oncogene family
chr4_-_40630826 0.72 ENST00000505414.5
ENST00000511598.5
RNA binding motif protein 47
chr11_-_90223036 0.72 ENST00000320585.11
cysteine and histidine rich domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 8.4 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.7 2.8 GO:1900229 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.7 4.2 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.7 2.0 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.6 1.7 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.5 7.0 GO:0072564 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.5 1.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.5 1.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.4 1.3 GO:0002818 intracellular defense response(GO:0002818)
0.4 1.7 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.4 1.7 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.4 1.2 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.4 2.7 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.4 1.5 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.4 1.1 GO:2000547 mesangial cell-matrix adhesion(GO:0035759) regulation of dendritic cell dendrite assembly(GO:2000547)
0.4 1.8 GO:0051866 general adaptation syndrome(GO:0051866)
0.3 1.4 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.3 1.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.3 0.6 GO:0002339 B cell selection(GO:0002339)
0.3 0.9 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.3 0.9 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.3 1.9 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.3 1.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.3 2.9 GO:0035995 detection of muscle stretch(GO:0035995)
0.3 0.8 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.3 1.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.3 0.8 GO:0000103 sulfate assimilation(GO:0000103)
0.3 1.8 GO:0071104 response to interleukin-9(GO:0071104)
0.3 0.8 GO:2000452 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.2 1.7 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 1.7 GO:0010266 response to vitamin B1(GO:0010266)
0.2 5.0 GO:0044146 negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.2 0.7 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.2 1.0 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.2 0.8 GO:0009631 cold acclimation(GO:0009631)
0.2 1.0 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.2 0.8 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 0.4 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.2 0.9 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.2 1.6 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 0.7 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.2 0.5 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.2 1.7 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.2 0.7 GO:0050705 regulation of interleukin-1 alpha secretion(GO:0050705)
0.2 0.8 GO:1990523 bone regeneration(GO:1990523)
0.1 0.9 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.7 GO:0097195 pilomotor reflex(GO:0097195)
0.1 1.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.7 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.9 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.7 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) renal protein absorption(GO:0097017) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.5 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.5 GO:1904349 regulation of small intestine smooth muscle contraction(GO:1904347) positive regulation of small intestine smooth muscle contraction(GO:1904349) small intestine smooth muscle contraction(GO:1990770)
0.1 1.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.4 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.1 0.7 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 1.9 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.1 1.3 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.1 0.8 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.9 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.7 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 0.3 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 2.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.5 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.5 GO:0090467 L-arginine import(GO:0043091) divalent metal ion export(GO:0070839) arginine import(GO:0090467)
0.1 0.7 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.1 1.0 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.2 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1 1.4 GO:0035608 protein deglutamylation(GO:0035608)
0.1 1.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.4 GO:0051413 response to cortisone(GO:0051413)
0.1 0.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 2.0 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1 0.3 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.2 GO:0002537 nitric oxide production involved in inflammatory response(GO:0002537)
0.1 1.5 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 0.2 GO:0002368 B cell cytokine production(GO:0002368)
0.1 1.7 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.1 1.2 GO:0015866 ADP transport(GO:0015866)
0.1 2.4 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 0.8 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.3 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.6 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.3 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 0.4 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 1.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.9 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.1 0.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.8 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.6 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1 0.2 GO:0018963 phthalate metabolic process(GO:0018963) epinephrine biosynthetic process(GO:0042418) phytoalexin metabolic process(GO:0052314)
0.1 0.7 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.1 0.3 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.7 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.3 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.2 GO:0071529 cementum mineralization(GO:0071529)
0.1 0.3 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.6 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1 0.2 GO:0036290 protein trans-autophosphorylation(GO:0036290) peptidyl-serine trans-autophosphorylation(GO:1990579)
0.1 0.5 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.1 0.8 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.3 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 1.0 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 0.3 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.4 GO:0070269 pyroptosis(GO:0070269)
0.1 1.2 GO:0042832 defense response to protozoan(GO:0042832)
0.1 1.1 GO:0015074 DNA integration(GO:0015074)
0.1 4.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 2.5 GO:0045730 respiratory burst(GO:0045730)
0.1 0.9 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 2.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 0.4 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.1 1.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.8 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.6 GO:0032494 response to peptidoglycan(GO:0032494)
0.1 1.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 1.7 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 2.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 1.1 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.7 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.5 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.3 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.6 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.4 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.8 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.7 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 1.1 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.7 GO:0070307 lens fiber cell development(GO:0070307)
0.0 1.8 GO:0097320 membrane tubulation(GO:0097320)
0.0 1.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 4.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.3 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.9 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 1.5 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.3 GO:0051697 protein delipidation(GO:0051697)
0.0 0.4 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.5 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 1.0 GO:0098743 cell aggregation(GO:0098743)
0.0 0.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 4.0 GO:0006968 cellular defense response(GO:0006968)
0.0 1.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.2 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.2 GO:0007620 copulation(GO:0007620)
0.0 0.4 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 1.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.7 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.5 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 1.4 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.8 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 1.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.3 GO:0032907 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
0.0 1.4 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.6 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 6.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.9 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.7 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.8 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.0 1.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.9 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 2.2 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.7 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.3 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.7 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 2.3 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.1 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.4 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:0006463 steroid hormone receptor complex assembly(GO:0006463)
0.0 2.8 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.8 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414) regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.2 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.2 GO:0009838 abscission(GO:0009838)
0.0 1.0 GO:0007140 male meiosis(GO:0007140)
0.0 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.7 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.6 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 1.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 1.0 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 2.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.6 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.5 GO:0045620 negative regulation of lymphocyte differentiation(GO:0045620)
0.0 1.6 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 0.3 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0 0.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.1 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.0 0.4 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.8 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.5 GO:0046040 IMP metabolic process(GO:0046040)
0.0 2.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.5 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.7 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 1.1 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.7 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.0 0.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.0 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 4.3 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.2 GO:0015825 L-serine transport(GO:0015825)
0.0 0.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.3 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:1990834 response to odorant(GO:1990834)
0.0 2.3 GO:0051028 mRNA transport(GO:0051028)
0.0 0.1 GO:0015846 polyamine transport(GO:0015846)
0.0 0.4 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.0 GO:0031247 actin rod assembly(GO:0031247)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.5 3.1 GO:0072557 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.3 1.0 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
0.3 1.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.3 1.5 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.3 1.8 GO:0032280 symmetric synapse(GO:0032280)
0.2 2.4 GO:0032010 phagolysosome(GO:0032010)
0.2 0.6 GO:0030849 autosome(GO:0030849)
0.2 2.6 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.2 1.4 GO:0071546 pi-body(GO:0071546)
0.2 3.3 GO:0005861 troponin complex(GO:0005861)
0.2 0.5 GO:0097414 glial cytoplasmic inclusion(GO:0097409) classical Lewy body(GO:0097414) Lewy neurite(GO:0097462) Lewy body corona(GO:1990038)
0.1 0.7 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 7.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.9 GO:0000801 central element(GO:0000801)
0.1 1.2 GO:0061574 ASAP complex(GO:0061574)
0.1 0.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.6 GO:0044292 dendrite terminus(GO:0044292)
0.1 6.9 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.7 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 1.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.8 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.7 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.3 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 4.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.8 GO:0032389 MutLalpha complex(GO:0032389)
0.1 2.5 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.8 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.3 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.1 0.2 GO:1990332 Ire1 complex(GO:1990332)
0.1 1.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 2.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.5 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.3 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.1 0.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 1.0 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 3.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 9.8 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 7.4 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 2.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.2 GO:0035363 histone locus body(GO:0035363)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.5 GO:0016600 flotillin complex(GO:0016600)
0.0 0.9 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 2.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.8 GO:0097342 ripoptosome(GO:0097342)
0.0 1.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.5 GO:0032059 bleb(GO:0032059)
0.0 4.0 GO:0005902 microvillus(GO:0005902)
0.0 2.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 8.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.8 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 2.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 2.3 GO:0005901 caveola(GO:0005901)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 2.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 2.0 GO:0034774 secretory granule lumen(GO:0034774)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.0 3.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 1.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.9 GO:0005657 replication fork(GO:0005657)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.2 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.6 3.0 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.6 7.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.4 1.3 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.4 4.4 GO:0019863 IgE binding(GO:0019863)
0.4 2.0 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.4 4.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.3 0.9 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.3 1.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.3 0.8 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.3 1.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 1.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.3 1.8 GO:0001515 opioid peptide activity(GO:0001515)
0.3 0.8 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.2 1.7 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 1.0 GO:0004912 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.2 1.7 GO:0005497 androgen binding(GO:0005497)
0.2 0.7 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.2 0.5 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 1.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 2.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 1.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.2 2.9 GO:0031433 telethonin binding(GO:0031433)
0.2 2.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 0.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 1.9 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.7 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 2.7 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.7 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.7 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.4 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.9 GO:0016936 galactoside binding(GO:0016936)
0.1 0.4 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.5 GO:0097677 STAT family protein binding(GO:0097677)
0.1 5.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.4 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 1.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.5 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.5 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 2.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.1 1.3 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.1 0.8 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 0.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.5 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.9 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.9 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 1.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.7 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 0.4 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 1.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 1.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 1.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.3 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 0.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 1.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.8 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 1.0 GO:0050693 LBD domain binding(GO:0050693)
0.1 4.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.6 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.1 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1 1.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.5 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.4 GO:0003916 DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 1.7 GO:0031489 myosin V binding(GO:0031489)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.2 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.0 0.1 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.0 0.6 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.0 1.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 8.5 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.4 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 1.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.6 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.5 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 2.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.5 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 1.0 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.7 GO:0045159 myosin II binding(GO:0045159)
0.0 1.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.7 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.8 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.7 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 4.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 1.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 2.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 3.7 GO:0031072 heat shock protein binding(GO:0031072)
0.0 1.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0016015 morphogen activity(GO:0016015)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 0.3 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.2 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.7 GO:0008494 translation activator activity(GO:0008494)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.9 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0032183 SUMO binding(GO:0032183)
0.0 0.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.6 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.8 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 4.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 1.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 2.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.0 PID IL5 PATHWAY IL5-mediated signaling events
0.1 3.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 5.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 2.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 3.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 2.5 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 2.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 3.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 5.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 2.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 3.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 2.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 2.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 7.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 3.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 11.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 3.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 2.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 3.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.9 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 3.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 1.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.9 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.8 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 2.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.0 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 2.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 1.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.3 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 2.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions