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Illumina Body Map 2 (GSE30611)

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Results for IRF3

Z-value: 1.71

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Transcription factors associated with IRF3

Gene Symbol Gene ID Gene Info
ENSG00000126456.16 interferon regulatory factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF3hg38_v1_chr19_-_49665603_496656170.392.7e-02Click!

Activity profile of IRF3 motif

Sorted Z-values of IRF3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_73982019 10.88 ENST00000296029.4
platelet factor 4
chr19_+_18173804 8.49 ENST00000407280.4
IFI30 lysosomal thiol reductase
chr17_-_35880350 8.48 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
C-C motif chemokine ligand 5
chr2_+_162318884 7.73 ENST00000446271.5
ENST00000429691.6
grancalcin
chr12_+_112978562 7.18 ENST00000680122.1
2'-5'-oligoadenylate synthetase 2
chr2_+_218260991 6.74 ENST00000522678.5
ENST00000519574.2
ENST00000521462.1
G protein-coupled bile acid receptor 1
chr3_-_36908503 6.49 ENST00000463764.2
tetratricopeptide repeat and ankyrin repeat containing 1
chr6_-_132763424 6.45 ENST00000532012.1
ENST00000525270.5
ENST00000530536.5
ENST00000524919.5
vanin 2
chr5_-_43040311 5.80 ENST00000616064.2
annexin A2 receptor
chr12_+_112978424 5.43 ENST00000680685.1
ENST00000620097.2
2'-5'-oligoadenylate synthetase 2
chr12_+_112978535 5.39 ENST00000552756.6
2'-5'-oligoadenylate synthetase 2
chr3_-_27722316 5.36 ENST00000449599.4
eomesodermin
chr7_-_93117956 5.34 ENST00000446617.1
ENST00000379958.3
ENST00000620985.4
sterile alpha motif domain containing 9
chr12_+_112978504 5.28 ENST00000392583.7
2'-5'-oligoadenylate synthetase 2
chr12_+_112978386 5.00 ENST00000342315.8
2'-5'-oligoadenylate synthetase 2
chr7_+_142587857 4.86 ENST00000617639.1
T cell receptor beta variable 14
chr1_+_151156627 4.81 ENST00000368910.4
TNF alpha induced protein 8 like 2
chr1_-_161069962 4.78 ENST00000368015.1
Rho GTPase activating protein 30
chr1_-_161069857 4.30 ENST00000368013.8
Rho GTPase activating protein 30
chr3_-_27722699 4.28 ENST00000461503.2
eomesodermin
chr15_+_88639009 4.02 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr6_+_31572279 3.98 ENST00000418386.3
lymphotoxin alpha
chr12_+_112978460 3.97 ENST00000449768.2
2'-5'-oligoadenylate synthetase 2
chr1_-_159076742 3.97 ENST00000368130.9
absent in melanoma 2
chr6_-_32853618 3.94 ENST00000354258.5
transporter 1, ATP binding cassette subfamily B member
chr4_-_168480477 3.93 ENST00000514748.5
ENST00000512371.1
ENST00000505890.5
ENST00000682922.1
ENST00000511577.5
DExD/H-box 60 like
chr3_+_186931344 3.87 ENST00000417392.5
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr7_-_93148345 3.85 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chr6_-_32853813 3.82 ENST00000643049.2
transporter 1, ATP binding cassette subfamily B member
chr8_-_66613208 3.72 ENST00000522677.8
MYB proto-oncogene like 1
chr10_+_89327989 3.59 ENST00000679923.1
ENST00000680085.1
ENST00000371818.9
ENST00000680779.1
interferon induced protein with tetratricopeptide repeats 3
chr5_-_95822711 3.56 ENST00000512469.2
ENST00000379979.8
ENST00000505427.1
ENST00000508780.5
ENST00000237858.11
glutaredoxin
chr6_+_26365215 3.48 ENST00000527422.5
ENST00000356386.6
ENST00000396948.5
butyrophilin subfamily 3 member A2
chr12_+_112938422 3.45 ENST00000680044.1
ENST00000680966.1
ENST00000548514.2
ENST00000681497.1
ENST00000551007.1
ENST00000228928.12
ENST00000680438.1
ENST00000681147.1
ENST00000679354.1
ENST00000681085.1
ENST00000680161.1
2'-5'-oligoadenylate synthetase 3
chr20_-_57620415 3.39 ENST00000371173.8
Z-DNA binding protein 1
chr15_+_44711487 3.36 ENST00000544417.5
ENST00000559916.1
ENST00000648006.3
beta-2-microglobulin
chr10_+_89327977 3.31 ENST00000681277.1
interferon induced protein with tetratricopeptide repeats 3
chr20_-_57620467 3.30 ENST00000395822.7
Z-DNA binding protein 1
chr6_+_32854179 3.19 ENST00000374859.3
proteasome 20S subunit beta 9
chr6_+_26365176 3.18 ENST00000377708.7
butyrophilin subfamily 3 member A2
chr11_-_4393650 3.10 ENST00000254436.8
tripartite motif containing 21
chr6_+_26402237 3.05 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
butyrophilin subfamily 3 member A1
chr11_+_63536801 3.04 ENST00000255688.8
ENST00000439013.6
phospholipase A and acyltransferase 4
chr12_+_112938523 3.00 ENST00000679483.1
ENST00000679493.1
2'-5'-oligoadenylate synthetase 3
chr6_+_26440472 2.98 ENST00000494393.5
ENST00000482451.5
ENST00000471353.5
ENST00000361232.7
ENST00000487627.5
ENST00000496719.1
ENST00000244519.7
ENST00000490254.5
ENST00000487272.1
butyrophilin subfamily 3 member A3
chr22_+_39077264 2.98 ENST00000407997.4
apolipoprotein B mRNA editing enzyme catalytic subunit 3G
chr19_+_49474208 2.92 ENST00000597551.6
ENST00000596435.5
ENST00000204637.6
ENST00000600429.5
fms related receptor tyrosine kinase 3 ligand
chr6_+_26365159 2.90 ENST00000532865.5
ENST00000396934.7
ENST00000508906.6
ENST00000530653.5
ENST00000527417.5
butyrophilin subfamily 3 member A2
chr15_+_75201873 2.86 ENST00000394987.5
chromosome 15 open reading frame 39
chr6_+_26402289 2.83 ENST00000414912.2
butyrophilin subfamily 3 member A1
chr1_+_78649818 2.76 ENST00000370747.9
ENST00000438486.1
interferon induced protein 44
chr11_-_57567260 2.74 ENST00000526659.1
ENST00000527022.1
ubiquitin conjugating enzyme E2 L6
chr19_+_49474561 2.73 ENST00000594009.5
ENST00000595510.1
ENST00000595815.1
fms related receptor tyrosine kinase 3 ligand
novel transcript
chr8_-_66613229 2.71 ENST00000517885.5
MYB proto-oncogene like 1
chr19_-_47232649 2.69 ENST00000449228.5
ENST00000300880.11
ENST00000341983.8
BCL2 binding component 3
chr2_-_162318129 2.67 ENST00000679938.1
interferon induced with helicase C domain 1
chr1_-_89198868 2.60 ENST00000355754.7
guanylate binding protein 4
chr2_-_230219944 2.58 ENST00000455674.2
ENST00000392048.7
ENST00000258381.11
ENST00000358662.9
ENST00000258382.10
SP110 nuclear body protein
chr6_+_31571957 2.56 ENST00000454783.5
lymphotoxin alpha
chr22_+_35648438 2.55 ENST00000409652.5
apolipoprotein L6
chr7_-_139109337 2.47 ENST00000464606.5
zinc finger CCCH-type containing, antiviral 1
chr14_-_20413420 2.46 ENST00000556935.5
ENST00000556549.1
ENST00000262715.10
telomerase associated protein 1
chr2_+_112095189 2.39 ENST00000649734.1
transmembrane protein 87B
chr1_+_1013485 2.34 ENST00000649529.1
ISG15 ubiquitin like modifier
chr9_+_5450503 2.33 ENST00000381573.8
ENST00000381577.4
CD274 molecule
chr21_+_41420515 2.31 ENST00000398600.6
ENST00000679626.1
MX dynamin like GTPase 1
chr8_+_27380629 2.28 ENST00000412793.5
protein tyrosine kinase 2 beta
chr2_-_230219902 2.27 ENST00000409815.6
SP110 nuclear body protein
chr7_-_106284524 2.27 ENST00000681936.1
ENST00000680786.1
ENST00000681550.1
nicotinamide phosphoribosyltransferase
chr1_+_112674416 2.24 ENST00000413052.6
ENST00000369645.5
Mov10 RISC complex RNA helicase
chr12_+_50504970 2.23 ENST00000301180.10
disco interacting protein 2 homolog B
chr15_-_44711306 2.18 ENST00000682850.1
PAT1 homolog 2
chr10_+_89301932 2.17 ENST00000371826.4
ENST00000679755.1
interferon induced protein with tetratricopeptide repeats 2
chr1_+_149475045 2.17 ENST00000651566.2
NBPF member 19
chr11_-_615570 2.17 ENST00000649187.1
ENST00000647801.1
ENST00000397566.5
ENST00000397570.5
interferon regulatory factor 7
chr7_-_139109702 2.11 ENST00000471652.1
ENST00000242351.10
zinc finger CCCH-type containing, antiviral 1
chr14_+_24136152 2.11 ENST00000559123.5
ENST00000206451.11
ENST00000382708.7
ENST00000561435.5
proteasome activator subunit 1
chr9_-_94640130 2.10 ENST00000414122.1
fructose-bisphosphatase 1
chr7_-_106285898 2.07 ENST00000424768.2
ENST00000681255.1
nicotinamide phosphoribosyltransferase
chr6_-_32838727 1.98 ENST00000652259.1
ENST00000374897.4
ENST00000620123.4
ENST00000452392.2
transporter 2, ATP binding cassette subfamily B member
novel protein, TAP2-HLA-DOB readthrough
chr4_+_118034480 1.94 ENST00000296499.6
N-deacetylase and N-sulfotransferase 3
chr20_-_57620393 1.91 ENST00000541799.1
Z-DNA binding protein 1
chr3_+_63911929 1.88 ENST00000487717.5
ataxin 7
chr3_+_187368367 1.88 ENST00000259030.3
receptor transporter protein 4
chrX_-_110318062 1.84 ENST00000372059.6
ENST00000262844.10
AMMECR nuclear protein 1
chr12_-_8066331 1.79 ENST00000546241.1
ENST00000307637.5
complement C3a receptor 1
chr7_-_140062841 1.78 ENST00000263549.8
poly(ADP-ribose) polymerase family member 12
chr11_-_615921 1.76 ENST00000348655.11
ENST00000525445.6
ENST00000330243.9
interferon regulatory factor 7
chr8_-_23069012 1.75 ENST00000347739.3
ENST00000276431.9
TNF receptor superfamily member 10b
chr3_-_122564232 1.75 ENST00000471785.5
ENST00000466126.1
poly(ADP-ribose) polymerase family member 9
chr11_-_57567617 1.72 ENST00000287156.9
ubiquitin conjugating enzyme E2 L6
chr17_-_65056659 1.71 ENST00000439174.7
G protein subunit alpha 13
chr18_+_24014733 1.66 ENST00000317571.8
tetratricopeptide repeat domain 39C
chr16_-_28211908 1.64 ENST00000566073.1
ENST00000304658.10
exportin 6
chr1_-_161044941 1.64 ENST00000368020.5
upstream transcription factor 1
chr12_-_98894830 1.63 ENST00000549797.5
ENST00000333732.11
ENST00000341752.11
ankyrin repeat and sterile alpha motif domain containing 1B
chrX_+_57286680 1.62 ENST00000374900.5
fatty acid amide hydrolase 2
chr5_-_96807899 1.61 ENST00000503921.5
ENST00000508227.5
ENST00000507154.1
ENST00000443439.7
endoplasmic reticulum aminopeptidase 1
chr1_-_154608140 1.60 ENST00000529168.2
ENST00000368474.9
ENST00000680305.1
ENST00000648231.2
adenosine deaminase RNA specific
chr9_-_32526185 1.58 ENST00000379883.3
ENST00000379868.6
ENST00000679859.1
DExD/H-box helicase 58
chr14_+_73058591 1.57 ENST00000525161.5
RNA binding motif protein 25
chr5_-_60843521 1.55 ENST00000511799.5
ELOVL fatty acid elongase 7
chr20_-_49278034 1.50 ENST00000371744.5
ENST00000396105.6
ENST00000371752.5
zinc finger NFX1-type containing 1
chr17_+_6755834 1.49 ENST00000346752.8
XIAP associated factor 1
chr3_+_122564327 1.45 ENST00000296161.9
ENST00000383661.3
deltex E3 ubiquitin ligase 3L
chr2_+_201116396 1.44 ENST00000395148.6
CASP8 and FADD like apoptosis regulator
chr8_-_143986425 1.42 ENST00000313059.9
ENST00000524918.5
ENST00000313028.12
ENST00000525773.5
poly(ADP-ribose) polymerase family member 10
chr20_-_25058115 1.42 ENST00000323482.9
acyl-CoA synthetase short chain family member 1
chr12_-_213656 1.41 ENST00000359674.8
solute carrier family 6 member 12
chr22_+_39040857 1.41 ENST00000381565.2
ENST00000308521.10
apolipoprotein B mRNA editing enzyme catalytic subunit 3F
chr3_-_122564253 1.41 ENST00000492382.5
ENST00000682323.1
ENST00000462315.5
poly(ADP-ribose) polymerase family member 9
chr3_+_122680802 1.40 ENST00000474629.7
poly(ADP-ribose) polymerase family member 14
chr1_+_112674649 1.40 ENST00000369644.5
Mov10 RISC complex RNA helicase
chr2_-_73642413 1.39 ENST00000272425.4
N-acetyltransferase 8 (putative)
chr7_-_904994 1.38 ENST00000453175.6
ArfGAP with dual PH domains 1
chr12_+_6452024 1.38 ENST00000266556.8
ENST00000544021.5
TAP binding protein like
chr17_-_42112674 1.37 ENST00000251642.8
ENST00000591220.5
DExH-box helicase 58
chr14_-_24146314 1.35 ENST00000559056.5
proteasome activator subunit 2
chr11_+_5624987 1.34 ENST00000429814.3
tripartite motif containing 34
chr22_+_31496275 1.33 ENST00000432498.5
SFI1 centrin binding protein
chr1_+_112674722 1.28 ENST00000357443.2
Mov10 RISC complex RNA helicase
chr9_-_98192614 1.27 ENST00000375077.5
coronin 2A
chr12_-_214146 1.26 ENST00000684302.1
solute carrier family 6 member 12
chr12_+_112938284 1.25 ENST00000681346.1
2'-5'-oligoadenylate synthetase 3
chr6_-_36387736 1.24 ENST00000373737.8
ENST00000373738.4
ENST00000538992.3
ENST00000615781.4
ENST00000620358.4
ETS variant transcription factor 7
chrX_+_120250752 1.24 ENST00000326624.2
ENST00000557385.2
zinc finger and BTB domain containing 33
chr14_-_24146596 1.23 ENST00000560410.5
ENST00000216802.10
ENST00000615264.4
ENST00000630027.1
proteasome activator subunit 2
chr11_+_66241227 1.20 ENST00000531597.1
phosphofurin acidic cluster sorting protein 1
chr1_-_161045961 1.20 ENST00000368021.7
upstream transcription factor 1
chr3_+_63912588 1.16 ENST00000522345.2
ataxin 7
chr2_-_213152427 1.16 ENST00000452786.2
IKAROS family zinc finger 2
chr9_-_92325577 1.15 ENST00000358855.8
ENST00000421075.6
ENST00000536624.5
nucleolar protein 8
chr1_-_161045873 1.11 ENST00000534633.5
upstream transcription factor 1
chr10_-_100286341 1.11 ENST00000441611.5
ENST00000614731.4
biogenesis of lysosomal organelles complex 1 subunit 2
chr2_-_165794642 1.11 ENST00000431484.1
ENST00000412248.5
polypeptide N-acetylgalactosaminyltransferase 3
chr22_+_31496387 1.10 ENST00000443011.5
ENST00000400288.7
ENST00000400289.5
ENST00000444859.5
SFI1 centrin binding protein
chr1_-_182589239 1.10 ENST00000367559.7
ENST00000539397.1
ribonuclease L
chr15_-_55319107 1.10 ENST00000565225.1
ENST00000436697.3
ENST00000567948.1
ENST00000563262.5
PIGB opposite strand 1
RAB27A, member RAS oncogene family
chr1_-_7940825 1.08 ENST00000377507.8
TNF receptor superfamily member 9
chr20_+_62804794 1.08 ENST00000290291.10
opioid growth factor receptor
chr20_-_25058168 1.08 ENST00000432802.6
acyl-CoA synthetase short chain family member 1
chr1_-_211188507 1.05 ENST00000450040.2
ENST00000638880.1
novel transcript
novel protein
chr13_+_108629605 1.05 ENST00000457511.7
myosin XVI
chr22_+_31496139 1.03 ENST00000540643.5
SFI1 centrin binding protein
chr1_+_25272527 1.02 ENST00000342055.9
ENST00000357542.8
ENST00000417538.6
ENST00000423810.6
ENST00000568195.5
Rh blood group D antigen
chr14_-_91510530 1.02 ENST00000557018.5
protein phosphatase 4 regulatory subunit 3A
chr3_-_122564577 1.01 ENST00000477522.6
ENST00000360356.6
poly(ADP-ribose) polymerase family member 9
chr9_-_92325322 0.98 ENST00000542613.5
ENST00000542053.5
ENST00000442668.7
ENST00000545558.5
ENST00000432670.6
ENST00000433029.6
ENST00000411621.6
nucleolar protein 8
chr2_-_144517663 0.98 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
zinc finger E-box binding homeobox 2
chr19_+_10086305 0.97 ENST00000253110.16
ENST00000591813.5
shiftless antiviral inhibitor of ribosomal frameshifting
chr7_-_127392060 0.97 ENST00000436992.5
zinc finger protein 800
chr14_-_100375602 0.97 ENST00000553395.5
ENST00000553545.5
ENST00000344102.9
ENST00000556338.5
ENST00000553934.1
tryptophanyl-tRNA synthetase 1
chr5_-_136365476 0.96 ENST00000378459.7
ENST00000502753.4
ENST00000513104.6
ENST00000352189.8
transient receptor potential cation channel subfamily C member 7
chr16_-_11256192 0.96 ENST00000644787.1
ENST00000332029.4
suppressor of cytokine signaling 1
chr10_+_89332484 0.95 ENST00000371811.4
ENST00000680037.1
ENST00000679583.1
ENST00000679897.1
interferon induced protein with tetratricopeptide repeats 3
chr20_-_35284715 0.94 ENST00000374436.7
ENST00000675032.1
eukaryotic translation initiation factor 6
chr4_+_129096113 0.94 ENST00000508673.5
chromosome 4 open reading frame 33
chr11_+_125591712 0.94 ENST00000527606.5
STT3 oligosaccharyltransferase complex catalytic subunit A
chr15_+_55319202 0.91 ENST00000164305.10
ENST00000566999.5
ENST00000539642.5
phosphatidylinositol glycan anchor biosynthesis class B
chr20_-_49278416 0.91 ENST00000371754.8
zinc finger NFX1-type containing 1
chr20_-_35284745 0.89 ENST00000374443.7
ENST00000374450.8
eukaryotic translation initiation factor 6
chr10_-_100286660 0.88 ENST00000370372.7
biogenesis of lysosomal organelles complex 1 subunit 2
chr8_-_108443409 0.86 ENST00000678023.1
ENST00000679198.1
ENST00000678881.1
ENST00000677084.1
ENST00000676663.1
ENST00000677614.1
ENST00000677040.1
ENST00000676487.1
ENST00000677409.1
ENST00000678797.1
ENST00000678334.1
eukaryotic translation initiation factor 3 subunit E
chr3_+_122680850 0.84 ENST00000494811.2
poly(ADP-ribose) polymerase family member 14
chr4_+_129096144 0.83 ENST00000425929.6
ENST00000508622.1
chromosome 4 open reading frame 33
chr20_+_408030 0.82 ENST00000640614.1
ENST00000475269.5
RANBP2-type and C3HC4-type zinc finger containing 1
chr12_-_214082 0.82 ENST00000535347.5
ENST00000536824.5
solute carrier family 6 member 12
chr16_-_29862890 0.82 ENST00000563415.1
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr5_-_96808093 0.81 ENST00000296754.7
endoplasmic reticulum aminopeptidase 1
chr10_-_14954018 0.79 ENST00000378241.5
ENST00000456122.1
ENST00000418843.5
ENST00000378249.5
ENST00000396817.6
ENST00000378255.5
ENST00000378254.5
ENST00000357717.6
ENST00000378258.5
ENST00000378246.6
ENST00000378278.7
DNA cross-link repair 1C
chr14_-_91510450 0.76 ENST00000555462.5
protein phosphatase 4 regulatory subunit 3A
chr11_-_67650682 0.76 ENST00000255082.8
aminoacylase 3
chr10_-_22003678 0.74 ENST00000376980.8
DnaJ heat shock protein family (Hsp40) member C1
chr16_-_29863117 0.74 ENST00000566113.5
ENST00000569956.5
ENST00000570016.5
ENST00000219789.11
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr20_+_45881218 0.73 ENST00000372523.1
zinc finger SWIM-type containing 1
chr19_-_39846329 0.73 ENST00000599134.1
ENST00000597634.5
ENST00000598417.5
ENST00000601274.5
ENST00000594309.5
ENST00000221801.8
fibrillarin
chr2_+_201116143 0.72 ENST00000443227.5
ENST00000309955.8
ENST00000341222.10
ENST00000341582.10
CASP8 and FADD like apoptosis regulator
chr18_+_24014390 0.70 ENST00000584250.1
tetratricopeptide repeat domain 39C
chr8_+_22589240 0.69 ENST00000450780.6
ENST00000430850.6
ENST00000447849.2
ENST00000614502.4
ENST00000443561.3
novel protein
PDZ and LIM domain 2
chr11_+_118359572 0.65 ENST00000252108.8
ENST00000431736.6
ubiquitination factor E4A
chr22_-_36239552 0.64 ENST00000454728.5
apolipoprotein L2
chr6_+_42050876 0.64 ENST00000465926.5
ENST00000482432.1
TATA-box binding protein associated factor 8
chr3_+_155870623 0.63 ENST00000295920.7
ENST00000496455.7
guanine monophosphate synthase
chr14_-_100375457 0.62 ENST00000556295.5
ENST00000554820.5
tryptophanyl-tRNA synthetase 1
chr14_-_75051426 0.62 ENST00000556257.5
ENST00000355774.7
ENST00000557648.1
ENST00000553263.1
ENST00000380968.6
mutL homolog 3
chr6_-_41071825 0.58 ENST00000468811.5
O-acyl-ADP-ribose deacylase 1
chr15_+_56918763 0.57 ENST00000557843.5
transcription factor 12
chr19_+_17405685 0.55 ENST00000646744.1
ENST00000635536.2
ENST00000635060.2
ENST00000634291.2
ENST00000645298.1
ENST00000528911.5
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chr20_+_408278 0.55 ENST00000356286.10
ENST00000382181.2
ENST00000400247.3
RANBP2-type and C3HC4-type zinc finger containing 1
chr20_+_408147 0.52 ENST00000441733.5
ENST00000353660.7
RANBP2-type and C3HC4-type zinc finger containing 1
chr19_+_50384323 0.52 ENST00000599857.7
ENST00000613923.6
ENST00000601098.6
ENST00000440232.7
ENST00000595904.6
ENST00000593887.1
DNA polymerase delta 1, catalytic subunit
chr6_-_36387654 0.52 ENST00000340181.9
ETS variant transcription factor 7
chr16_-_28506826 0.48 ENST00000356897.1
interleukin 27
chr20_-_21514046 0.44 ENST00000377142.5
NK2 homeobox 2
chr3_+_130443484 0.44 ENST00000512482.1
collagen type VI alpha 5 chain
chr2_+_201116238 0.42 ENST00000342795.9
CASP8 and FADD like apoptosis regulator
chr7_+_135148041 0.40 ENST00000275767.3
transmembrane protein 140
chr2_+_218069248 0.39 ENST00000374155.7
RUN and FYVE domain containing 4
chr6_+_42050513 0.39 ENST00000372978.7
ENST00000494547.5
ENST00000456846.6
ENST00000372982.8
ENST00000472818.5
ENST00000372977.8
TATA-box binding protein associated factor 8
chr9_+_92325910 0.37 ENST00000375587.8
ENST00000618653.1
centromere protein P

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:0046967 cytosol to ER transport(GO:0046967)
3.2 9.6 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
2.2 6.5 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
2.1 32.2 GO:0018377 protein myristoylation(GO:0018377)
2.1 8.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.7 3.4 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428)
1.6 10.9 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
1.4 1.4 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
1.1 5.7 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
1.0 4.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.9 10.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.8 3.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.8 3.9 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.7 6.7 GO:0038183 bile acid signaling pathway(GO:0038183)
0.7 3.9 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.6 9.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.6 7.7 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.6 4.0 GO:0070269 pyroptosis(GO:0070269)
0.6 4.0 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.5 4.4 GO:0070383 DNA cytosine deamination(GO:0070383)
0.5 2.2 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.5 1.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.5 2.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.5 6.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.5 7.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.5 2.5 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.5 15.4 GO:0072643 interferon-gamma secretion(GO:0072643)
0.4 4.9 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.4 2.3 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.4 6.5 GO:0015939 pantothenate metabolic process(GO:0015939)
0.4 1.8 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.3 1.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.3 1.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.3 1.6 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.3 3.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 0.7 GO:0033967 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.2 2.9 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 1.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 4.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.2 1.6 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 2.3 GO:2001179 interleukin-10 secretion(GO:0072608) regulation of interleukin-10 secretion(GO:2001179) positive regulation of interleukin-10 secretion(GO:2001181)
0.2 0.6 GO:0051805 evasion or tolerance of host immune response(GO:0020012) evasion or tolerance of host defense response(GO:0030682) evasion or tolerance by virus of host immune response(GO:0030683) evasion or tolerance of immune response of other organism involved in symbiotic interaction(GO:0051805) evasion or tolerance of defense response of other organism involved in symbiotic interaction(GO:0051807)
0.2 0.9 GO:0043686 co-translational protein modification(GO:0043686)
0.2 1.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 1.9 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 1.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.4 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 3.9 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 2.1 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 1.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 16.4 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 2.5 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 3.5 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 0.6 GO:0009139 dUDP biosynthetic process(GO:0006227) dTDP biosynthetic process(GO:0006233) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dTDP metabolic process(GO:0046072) dUDP metabolic process(GO:0046077)
0.1 2.0 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 1.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 3.6 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 2.3 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.1 1.0 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.1 0.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 1.0 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 1.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 8.6 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.1 1.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 1.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 1.0 GO:0006828 manganese ion transport(GO:0006828)
0.1 1.6 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.0 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.5 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.5 GO:0015695 organic cation transport(GO:0015695)
0.0 0.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.6 GO:0007144 female meiosis I(GO:0007144)
0.0 1.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 1.1 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.4 GO:0009249 protein lipoylation(GO:0009249)
0.0 1.5 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.8 GO:0033151 V(D)J recombination(GO:0033151)
0.0 1.2 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 4.8 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 3.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.9 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 1.4 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 1.6 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 7.1 GO:0061025 membrane fusion(GO:0061025)
0.0 0.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 1.3 GO:0070206 protein trimerization(GO:0070206)
0.0 0.7 GO:0035456 response to interferon-beta(GO:0035456)
0.0 1.6 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 1.4 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 3.1 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 8.2 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.9 GO:0020005 symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
1.4 9.7 GO:0042825 TAP complex(GO:0042825)
1.2 4.7 GO:0008537 proteasome activator complex(GO:0008537)
1.1 4.4 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.7 3.4 GO:0031905 early endosome lumen(GO:0031905)
0.7 4.0 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.4 3.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 3.9 GO:0016589 NURF complex(GO:0016589)
0.2 1.9 GO:0071797 LUBAC complex(GO:0071797)
0.2 1.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.7 GO:0001651 dense fibrillar component(GO:0001651)
0.1 5.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.6 GO:0005712 chiasma(GO:0005712)
0.1 2.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 2.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 2.5 GO:0005682 U5 snRNP(GO:0005682)
0.1 2.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.8 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 11.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 7.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 3.1 GO:0015030 Cajal body(GO:0015030)
0.0 1.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 4.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 37.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 5.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 4.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.4 GO:0005811 lipid particle(GO:0005811)
0.0 8.8 GO:0005769 early endosome(GO:0005769)
0.0 2.2 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.0 GO:0032002 interleukin-28 receptor complex(GO:0032002)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0003692 left-handed Z-DNA binding(GO:0003692)
2.5 39.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
2.2 10.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.7 8.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.6 6.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
1.3 4.0 GO:0008859 exoribonuclease II activity(GO:0008859)
1.2 9.7 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.9 4.3 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.7 6.7 GO:0038181 bile acid receptor activity(GO:0038181)
0.6 2.4 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.6 3.0 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.5 2.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.5 4.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.5 2.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4 1.7 GO:0045569 TRAIL binding(GO:0045569)
0.4 4.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.4 6.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4 3.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.4 3.6 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.4 2.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.4 3.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.3 1.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.3 8.7 GO:0070403 NAD+ binding(GO:0070403)
0.2 1.7 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 0.7 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.2 1.9 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 1.9 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.2 1.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 0.6 GO:0033862 UMP kinase activity(GO:0033862)
0.2 2.5 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2 1.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 2.3 GO:0031386 protein tag(GO:0031386)
0.2 7.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 1.6 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.2 0.9 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 1.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 4.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 6.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 1.8 GO:0004875 complement receptor activity(GO:0004875)
0.1 1.6 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 9.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 3.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 8.5 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.1 0.8 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.4 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.1 0.6 GO:0003696 satellite DNA binding(GO:0003696)
0.1 1.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 4.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 1.1 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.9 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 2.9 GO:0005123 death receptor binding(GO:0005123)
0.0 12.4 GO:0004386 helicase activity(GO:0004386)
0.0 5.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 1.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 2.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 1.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.8 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 1.1 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 3.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 2.7 GO:0051117 ATPase binding(GO:0051117)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.1 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0019213 deacetylase activity(GO:0019213)
0.0 7.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.6 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.9 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 14.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 15.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 10.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 8.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 4.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 2.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 4.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 2.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 3.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.6 10.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 64.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.5 12.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 3.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2 3.9 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.2 8.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 2.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 4.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 4.0 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 7.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 4.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 8.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 5.7 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.1 3.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.7 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 1.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 6.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 7.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 8.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events