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Illumina Body Map 2 (GSE30611)

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Results for IRF6_IRF4_IRF5

Z-value: 1.25

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Transcription factors associated with IRF6_IRF4_IRF5

Gene Symbol Gene ID Gene Info
ENSG00000117595.12 interferon regulatory factor 6
ENSG00000137265.15 interferon regulatory factor 4
ENSG00000128604.20 interferon regulatory factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF5hg38_v1_chr7_+_128937917_1289379940.602.9e-04Click!
IRF4hg38_v1_chr6_+_391743_3917590.402.2e-02Click!
IRF6hg38_v1_chr1_-_209802149_209802166-0.067.4e-01Click!

Activity profile of IRF6_IRF4_IRF5 motif

Sorted Z-values of IRF6_IRF4_IRF5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_169711603 6.05 ENST00000236147.6
ENST00000650983.1
selectin L
chr10_-_124093582 5.83 ENST00000462406.1
ENST00000435907.6
carbohydrate sulfotransferase 15
chr19_+_16143678 5.54 ENST00000613986.4
ENST00000593031.1
hematopoietic SH2 domain containing
chr14_+_22462932 4.59 ENST00000390477.2
T cell receptor delta constant
chr8_+_8701891 3.58 ENST00000519106.2
claudin 23
chr17_-_81512671 3.46 ENST00000679480.1
ENST00000644774.2
ENST00000571721.6
ENST00000575842.5
ENST00000575087.5
ENST00000573283.7
ENST00000571691.6
ENST00000570382.2
actin gamma 1
chr5_+_76819022 3.17 ENST00000296677.5
F2R like trypsin receptor 1
chr3_-_146544538 3.05 ENST00000462666.5
phospholipid scramblase 1
chr4_+_69051362 3.02 ENST00000502942.5
UDP glucuronosyltransferase family 2 member B7
chr9_-_98119184 2.98 ENST00000342043.3
ENST00000375098.7
ENST00000341469.7
tripartite motif containing 14
chr3_-_146544578 2.69 ENST00000342435.9
ENST00000448787.6
phospholipid scramblase 1
chr3_-_146544701 2.59 ENST00000487389.5
phospholipid scramblase 1
chr3_-_146544850 2.53 ENST00000472349.1
phospholipid scramblase 1
chr9_+_111896804 2.47 ENST00000374279.4
UDP-glucose ceramide glucosyltransferase
chr11_-_118264282 2.36 ENST00000278937.7
myelin protein zero like 2
chr17_+_27631148 2.35 ENST00000313648.10
ENST00000395473.7
ENST00000577392.5
ENST00000584661.5
galectin 9
chr1_-_58577244 2.23 ENST00000371225.4
tumor associated calcium signal transducer 2
chr3_-_146544636 2.22 ENST00000486631.5
phospholipid scramblase 1
chr6_-_106975452 2.19 ENST00000619869.1
ENST00000619133.4
CD24 molecule
chr6_-_106975309 2.18 ENST00000615659.1
CD24 molecule
chr17_+_43211835 2.16 ENST00000588693.5
ENST00000588659.5
ENST00000541594.5
ENST00000536052.5
ENST00000612339.4
transmembrane protein 106A
chr11_-_615921 2.05 ENST00000348655.11
ENST00000525445.6
ENST00000330243.9
interferon regulatory factor 7
chr17_-_7261092 1.92 ENST00000574070.5
claudin 7
chr11_-_118264445 1.88 ENST00000438295.2
myelin protein zero like 2
chr12_+_6772512 1.85 ENST00000441671.6
ENST00000203629.3
lymphocyte activating 3
chr17_+_18476737 1.84 ENST00000581545.5
ENST00000582333.5
ENST00000328114.11
ENST00000583322.5
ENST00000584941.5
galectin 9C
chr2_+_218260991 1.82 ENST00000522678.5
ENST00000519574.2
ENST00000521462.1
G protein-coupled bile acid receptor 1
chr7_-_139109337 1.81 ENST00000464606.5
zinc finger CCCH-type containing, antiviral 1
chr7_-_139109702 1.80 ENST00000471652.1
ENST00000242351.10
zinc finger CCCH-type containing, antiviral 1
chr21_+_41426031 1.78 ENST00000455164.6
ENST00000681849.1
ENST00000679705.1
ENST00000424365.6
MX dynamin like GTPase 1
chr11_-_615570 1.77 ENST00000649187.1
ENST00000647801.1
ENST00000397566.5
ENST00000397570.5
interferon regulatory factor 7
chr13_-_46387447 1.76 ENST00000676051.1
ENST00000378787.7
ENST00000378781.7
ENST00000378797.6
rubicon like autophagy enhancer
chr6_-_106975616 1.74 ENST00000610952.1
CD24 molecule
chr11_-_57567260 1.71 ENST00000526659.1
ENST00000527022.1
ubiquitin conjugating enzyme E2 L6
chr19_+_17527250 1.70 ENST00000599164.6
ENST00000449408.6
ENST00000600871.5
ENST00000599124.1
niban apoptosis regulator 3
chr21_+_41361999 1.67 ENST00000436410.5
ENST00000435611.6
ENST00000330714.8
MX dynamin like GTPase 2
chr1_+_241532370 1.65 ENST00000366559.9
ENST00000366557.8
kynurenine 3-monooxygenase
chr11_-_320774 1.65 ENST00000681198.1
ENST00000399808.5
ENST00000680209.1
ENST00000681304.1
ENST00000681840.1
interferon induced transmembrane protein 3
chr4_-_11428868 1.64 ENST00000002596.6
heparan sulfate-glucosamine 3-sulfotransferase 1
chr11_+_5689780 1.54 ENST00000379965.8
ENST00000454828.5
tripartite motif containing 22
chr1_-_161021096 1.53 ENST00000537746.1
ENST00000368026.11
F11 receptor
chr12_+_45729682 1.50 ENST00000334344.11
AT-rich interaction domain 2
chr11_+_32829903 1.44 ENST00000257836.4
proline rich and Gla domain 4
chr13_-_42992165 1.44 ENST00000398762.7
ENST00000313640.11
ENST00000313624.12
epithelial stromal interaction 1
chr6_+_31946086 1.38 ENST00000425368.7
complement factor B
chr11_-_57567617 1.38 ENST00000287156.9
ubiquitin conjugating enzyme E2 L6
chr17_-_47957824 1.37 ENST00000300557.3
proline rich 15 like
chr7_-_140062841 1.36 ENST00000263549.8
poly(ADP-ribose) polymerase family member 12
chr21_+_41426197 1.36 ENST00000680942.1
ENST00000288383.11
ENST00000679386.1
MX dynamin like GTPase 1
chr16_-_74700786 1.33 ENST00000306247.11
ENST00000575686.1
mixed lineage kinase domain like pseudokinase
chr7_+_30284574 1.30 ENST00000323037.5
zinc and ring finger 2
chr12_-_51270175 1.29 ENST00000604188.1
ENST00000398453.7
small cell adhesion glycoprotein
chr11_-_65780917 1.28 ENST00000532090.3
adaptor related protein complex 5 subunit beta 1
chr11_+_130159773 1.28 ENST00000278742.6
ST14 transmembrane serine protease matriptase
chr17_-_20467535 1.27 ENST00000324290.5
ENST00000423676.8
galectin 9B
chr1_-_206946448 1.26 ENST00000356495.5
polymeric immunoglobulin receptor
chr12_+_75480800 1.25 ENST00000456650.7
GLI pathogenesis related 1
chr3_+_155080307 1.24 ENST00000360490.7
membrane metalloendopeptidase
chr19_+_51761167 1.23 ENST00000340023.7
ENST00000599326.1
ENST00000598953.1
formyl peptide receptor 2
chr3_+_114294020 1.22 ENST00000383671.8
T cell immunoreceptor with Ig and ITIM domains
chr7_-_77416300 1.22 ENST00000257626.12
gamma-secretase activating protein
chr11_+_125063295 1.21 ENST00000532000.5
ENST00000403796.7
ENST00000308074.4
solute carrier family 37 member 2
chr21_+_41426168 1.21 ENST00000681266.1
ENST00000417963.6
MX dynamin like GTPase 1
chr5_+_69492767 1.20 ENST00000681041.1
ENST00000680098.1
ENST00000680784.1
ENST00000396442.7
ENST00000681895.1
occludin
chrX_+_23783163 1.14 ENST00000379254.5
ENST00000379270.5
ENST00000683890.1
spermidine/spermine N1-acetyltransferase 1
novel protein
chr3_+_187368367 1.12 ENST00000259030.3
receptor transporter protein 4
chr16_+_11965193 1.10 ENST00000053243.6
ENST00000396495.3
TNF receptor superfamily member 17
chr16_-_11256192 1.09 ENST00000644787.1
ENST00000332029.4
suppressor of cytokine signaling 1
chr7_-_150800320 1.07 ENST00000492607.5
ENST00000326442.10
ENST00000450753.2
transmembrane protein 176B
chr17_-_56914032 1.07 ENST00000537230.3
ENST00000316881.9
tripartite motif containing 25
chr17_-_31318818 1.07 ENST00000578584.5
novel protein
chr12_+_75480745 1.07 ENST00000266659.8
GLI pathogenesis related 1
chr2_-_189582012 1.07 ENST00000427419.5
ENST00000455320.5
solute carrier family 40 member 1
chr12_+_112938422 1.03 ENST00000680044.1
ENST00000680966.1
ENST00000548514.2
ENST00000681497.1
ENST00000551007.1
ENST00000228928.12
ENST00000680438.1
ENST00000681147.1
ENST00000679354.1
ENST00000681085.1
ENST00000680161.1
2'-5'-oligoadenylate synthetase 3
chr12_+_75481204 1.01 ENST00000550491.1
GLI pathogenesis related 1
chr12_-_51270351 0.97 ENST00000603798.6
small cell adhesion glycoprotein
chr7_-_20217342 0.97 ENST00000400331.10
ENST00000332878.8
MET transcriptional regulator MACC1
chr1_-_151992571 0.95 ENST00000368809.1
S100 calcium binding protein A10
chr13_-_46387724 0.95 ENST00000675585.1
rubicon like autophagy enhancer
chr17_-_38825303 0.95 ENST00000614790.5
CWC25 spliceosome associated protein homolog
chr15_+_74782574 0.95 ENST00000567123.1
ENST00000569462.5
C-terminal Src kinase
chr6_+_26365215 0.94 ENST00000527422.5
ENST00000356386.6
ENST00000396948.5
butyrophilin subfamily 3 member A2
chr6_+_30489501 0.94 ENST00000376630.5
major histocompatibility complex, class I, E
chrX_+_9465206 0.93 ENST00000422314.5
transducin beta like 1 X-linked
chr19_+_58387260 0.92 ENST00000598098.5
ENST00000598495.5
ENST00000196551.8
ENST00000596046.1
ribosomal protein S5
chr10_-_89414458 0.91 ENST00000371837.5
lipase A, lysosomal acid type
chr16_+_66604100 0.88 ENST00000562357.5
ENST00000562707.5
ENST00000361909.8
ENST00000460097.5
ENST00000565666.5
CKLF like MARVEL transmembrane domain containing 3
chr11_+_5689691 0.88 ENST00000425490.5
tripartite motif containing 22
chr2_+_68734773 0.88 ENST00000409202.8
Rho GTPase activating protein 25
chr2_+_68734861 0.87 ENST00000467265.5
Rho GTPase activating protein 25
chr2_-_162318129 0.87 ENST00000679938.1
interferon induced with helicase C domain 1
chr8_+_23528947 0.86 ENST00000519973.6
solute carrier family 25 member 37
chr11_-_67374168 0.85 ENST00000533438.1
cardiotrophin like cytokine factor 1
chr6_+_26365176 0.85 ENST00000377708.7
butyrophilin subfamily 3 member A2
chr1_+_179082025 0.85 ENST00000367625.8
ENST00000367627.8
ENST00000352445.10
torsin family 3 member A
chr3_+_178419123 0.85 ENST00000614557.1
ENST00000455307.5
ENST00000436432.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript)
long intergenic non-protein coding RNA 1014
chr8_+_23528995 0.85 ENST00000523930.1
solute carrier family 25 member 37
chr6_+_106098933 0.84 ENST00000369089.3
PR/SET domain 1
chr15_+_74782069 0.84 ENST00000220003.14
ENST00000439220.6
C-terminal Src kinase
chr20_-_63572455 0.83 ENST00000467148.1
helicase with zinc finger 2
chr5_+_119333151 0.82 ENST00000513374.1
TNF alpha induced protein 8
chr21_+_41426590 0.80 ENST00000679543.1
ENST00000680364.1
MX dynamin like GTPase 1
chr17_+_80260826 0.80 ENST00000508628.6
ENST00000582970.5
ENST00000319921.4
ring finger protein 213
chr19_+_17527232 0.80 ENST00000601861.5
niban apoptosis regulator 3
chr12_+_112938523 0.79 ENST00000679483.1
ENST00000679493.1
2'-5'-oligoadenylate synthetase 3
chr14_+_22422371 0.79 ENST00000390469.2
T cell receptor delta variable 2
chr8_-_143986425 0.79 ENST00000313059.9
ENST00000524918.5
ENST00000313028.12
ENST00000525773.5
poly(ADP-ribose) polymerase family member 10
chr12_+_12891554 0.78 ENST00000014914.6
G protein-coupled receptor class C group 5 member A
chr12_-_51269949 0.77 ENST00000603864.5
ENST00000605426.5
small cell adhesion glycoprotein
chr19_+_53365687 0.76 ENST00000491101.5
ENST00000474037.6
ENST00000467003.1
ENST00000475179.5
ENST00000593918.1
zinc finger protein 525
chr1_-_25875669 0.75 ENST00000675840.1
progestin and adipoQ receptor family member 7
chr15_+_90884461 0.75 ENST00000559355.5
ENST00000394302.5
FES proto-oncogene, tyrosine kinase
chr22_+_23145366 0.74 ENST00000341989.9
ENST00000263116.8
RAB36, member RAS oncogene family
chr1_+_241532121 0.73 ENST00000366558.7
kynurenine 3-monooxygenase
chr12_+_68610918 0.73 ENST00000538980.5
ENST00000542018.5
ENST00000543393.5
ENST00000534899.5
ENST00000453560.6
ENST00000378985.7
ENST00000540209.5
ENST00000540781.5
ENST00000535492.5
ENST00000539091.5
ENST00000542145.5
ENST00000485252.6
ENST00000541386.5
ENST00000538877.5
ENST00000543697.5
RAP1B, member of RAS oncogene family
chr5_+_76818933 0.73 ENST00000514165.1
F2R like trypsin receptor 1
chr10_+_69801892 0.73 ENST00000398978.8
ENST00000645393.2
ENST00000354547.7
ENST00000674121.1
ENST00000673842.1
ENST00000520267.5
collagen type XIII alpha 1 chain
chr15_+_90884429 0.69 ENST00000414248.6
FES proto-oncogene, tyrosine kinase
chr16_+_68085420 0.68 ENST00000349223.9
nuclear factor of activated T cells 3
chr6_+_32637396 0.68 ENST00000395363.5
ENST00000496318.5
ENST00000343139.11
major histocompatibility complex, class II, DQ alpha 1
chr6_+_32637419 0.66 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr9_-_32526185 0.66 ENST00000379883.3
ENST00000379868.6
ENST00000679859.1
DExD/H-box helicase 58
chr12_-_51269898 0.66 ENST00000603838.5
small cell adhesion glycoprotein
chr2_+_162318884 0.65 ENST00000446271.5
ENST00000429691.6
grancalcin
chr4_-_163613505 0.65 ENST00000339875.9
membrane associated ring-CH-type finger 1
chrX_+_22136552 0.65 ENST00000682888.1
ENST00000684356.1
phosphate regulating endopeptidase homolog X-linked
chr13_+_49495941 0.65 ENST00000378319.8
ENST00000496623.5
ENST00000426879.5
PHD finger protein 11
chr16_+_66603874 0.65 ENST00000563672.5
ENST00000424011.6
CKLF like MARVEL transmembrane domain containing 3
chr11_+_120210991 0.65 ENST00000328965.9
out at first homolog
chr16_-_88785210 0.64 ENST00000301015.14
piezo type mechanosensitive ion channel component 1
chr10_+_69802424 0.64 ENST00000673802.2
ENST00000517713.5
ENST00000520133.5
ENST00000522165.5
ENST00000673641.2
ENST00000673628.2
collagen type XIII alpha 1 chain
chr6_+_89081787 0.63 ENST00000354922.3
proline rich nuclear receptor coactivator 1
chr12_-_51270274 0.63 ENST00000605627.1
small cell adhesion glycoprotein
chr3_-_183162726 0.63 ENST00000265598.8
lysosomal associated membrane protein 3
chr1_+_78303865 0.62 ENST00000370758.5
prostaglandin F receptor
chr12_+_6226136 0.61 ENST00000676764.1
ENST00000646407.1
CD9 molecule
chr4_-_39527558 0.61 ENST00000515021.5
ENST00000510490.1
UDP-glucose 6-dehydrogenase
chr17_-_78782257 0.61 ENST00000591455.5
ENST00000446868.7
ENST00000361101.8
ENST00000589296.5
cytohesin 1
chr1_+_220879434 0.60 ENST00000366903.8
H2.0 like homeobox
chr18_-_69956924 0.60 ENST00000581982.5
ENST00000280200.8
CD226 molecule
chr7_+_143288215 0.59 ENST00000619992.4
ENST00000310447.10
caspase 2
chr10_+_89414555 0.59 ENST00000371795.5
ENST00000681422.1
interferon induced protein with tetratricopeptide repeats 5
chr22_+_35648438 0.59 ENST00000409652.5
apolipoprotein L6
chr11_+_809961 0.58 ENST00000321153.9
ENST00000530797.5
ribosomal protein lateral stalk subunit P2
chr1_+_45550783 0.58 ENST00000621846.4
ENST00000434299.5
ENST00000351829.9
aldo-keto reductase family 1 member A1
chr19_-_9435551 0.56 ENST00000651268.1
ENST00000592904.7
zinc finger protein 266
chr16_+_68085344 0.56 ENST00000575270.5
ENST00000346183.8
nuclear factor of activated T cells 3
chr19_-_9435490 0.56 ENST00000592292.5
ENST00000588221.5
zinc finger protein 266
chr16_+_30740621 0.54 ENST00000615541.3
ENST00000483578.1
transmembrane protein 265
novel transcript
chr8_-_23069012 0.54 ENST00000347739.3
ENST00000276431.9
TNF receptor superfamily member 10b
chr1_+_45551031 0.53 ENST00000481885.5
ENST00000471651.1
aldo-keto reductase family 1 member A1
chr7_+_43758671 0.52 ENST00000265523.9
ENST00000402924.5
biliverdin reductase A
chrX_+_9465011 0.52 ENST00000645353.2
transducin beta like 1 X-linked
chr12_+_45729899 0.52 ENST00000422737.6
AT-rich interaction domain 2
chr7_-_151082908 0.52 ENST00000462940.1
ENST00000492838.1
ENST00000392818.7
ENST00000488752.5
ENST00000476627.5
transmembrane and ubiquitin like domain containing 1
chr9_-_75028274 0.51 ENST00000376834.8
carnosine N-methyltransferase 1
chr17_+_49219503 0.51 ENST00000573347.5
ABI family member 3
chr8_+_91249307 0.51 ENST00000309536.6
ENST00000276609.8
solute carrier family 26 member 7
chr15_-_75455767 0.51 ENST00000360439.8
SIN3 transcription regulator family member A
chr2_-_231125032 0.51 ENST00000258400.4
5-hydroxytryptamine receptor 2B
chr18_+_44680875 0.51 ENST00000649279.2
ENST00000677699.1
SET binding protein 1
chr7_+_143288364 0.50 ENST00000392925.6
caspase 2
chr13_+_50909745 0.49 ENST00000422660.6
ENST00000645188.1
ENST00000646731.1
ENST00000643774.1
ENST00000646960.1
ENST00000637648.2
ENST00000336617.8
ribonuclease H2 subunit B
chr6_-_33314055 0.49 ENST00000434618.7
TAP binding protein
chr1_-_52552994 0.49 ENST00000355809.4
ENST00000528642.5
ENST00000470626.1
ENST00000257177.9
ENST00000371544.7
terminal uridylyl transferase 4
chr1_-_154608705 0.48 ENST00000649749.1
ENST00000648871.1
adenosine deaminase RNA specific
chr12_+_53380639 0.47 ENST00000426431.2
Sp1 transcription factor
chr11_+_77066948 0.47 ENST00000527066.5
ENST00000648180.1
ENST00000529629.5
calpain 5
chr19_-_54183556 0.46 ENST00000495279.2
membrane bound O-acyltransferase domain containing 7
chr21_+_41426232 0.45 ENST00000398598.8
ENST00000681896.1
ENST00000680629.1
ENST00000680760.1
ENST00000680176.1
ENST00000680776.1
ENST00000681607.1
ENST00000680536.1
MX dynamin like GTPase 1
chr11_+_44726811 0.45 ENST00000533202.5
ENST00000520358.7
ENST00000533080.5
ENST00000520999.6
tetraspanin 18
chr17_-_39927549 0.44 ENST00000579695.5
ENST00000304046.7
ORMDL sphingolipid biosynthesis regulator 3
chr8_-_100950549 0.44 ENST00000395951.7
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr12_-_57846686 0.44 ENST00000548823.1
ENST00000398073.7
CTD small phosphatase 2
chr3_-_15333152 0.44 ENST00000426925.5
SH3 domain binding protein 5
chr6_+_26087281 0.43 ENST00000353147.9
ENST00000397022.7
ENST00000352392.8
ENST00000349999.8
ENST00000317896.11
ENST00000470149.5
ENST00000336625.12
ENST00000461397.5
ENST00000488199.5
homeostatic iron regulator
chr1_-_153541765 0.43 ENST00000368718.5
S100 calcium binding protein A5
chr19_+_55385928 0.43 ENST00000431533.6
ENST00000428193.6
ENST00000558815.5
ENST00000344063.7
ENST00000560583.5
ENST00000560055.5
ENST00000559463.5
ribosomal protein L28
chr9_+_6413191 0.43 ENST00000276893.10
ubiquitin like with PHD and ring finger domains 2
chr1_-_53889766 0.42 ENST00000371399.5
ENST00000072644.7
Yip1 domain family member 1
chr21_+_41426289 0.42 ENST00000679408.1
ENST00000681039.1
ENST00000681671.1
MX dynamin like GTPase 1
chr19_-_56824314 0.42 ENST00000593931.1
zinc finger imprinted 2
chr6_-_127900958 0.41 ENST00000434358.3
ENST00000630369.2
ENST00000368248.4
thymocyte selection associated
chr4_-_88523740 0.41 ENST00000273968.5
ENST00000527353.2
PIGY upstream reading frame
phosphatidylinositol glycan anchor biosynthesis class Y
chr1_-_182589239 0.41 ENST00000367559.7
ENST00000539397.1
ribonuclease L
chr22_-_31292445 0.40 ENST00000402249.7
ENST00000215912.10
ENST00000443175.1
ENST00000441972.5
phosphoinositide-3-kinase interacting protein 1
chr12_+_62260338 0.40 ENST00000353364.7
ENST00000549523.5
ubiquitin specific peptidase 15
chr17_-_4739866 0.40 ENST00000574412.6
ENST00000293778.12
C-X-C motif chemokine ligand 16
chr19_+_36214602 0.39 ENST00000456324.5
zinc finger protein 146
chr16_+_11965234 0.39 ENST00000562385.1
TNF receptor superfamily member 17
chr18_+_3262956 0.39 ENST00000584539.1
myosin light chain 12B
chr6_+_32969345 0.38 ENST00000678250.1
bromodomain containing 2
chr2_-_99181010 0.37 ENST00000409107.1
ENST00000289359.6
microtubule interacting and trafficking domain containing 1
chr6_+_89146046 0.37 ENST00000275072.5
peptidase M20 domain containing 2
chr4_-_82374143 0.37 ENST00000507010.5
ENST00000503822.1
heterogeneous nuclear ribonucleoprotein D
chr10_+_100745711 0.37 ENST00000370296.6
ENST00000428433.5
paired box 2
chr7_+_90403506 0.37 ENST00000427904.1
claudin 12
chrX_-_119943603 0.37 ENST00000652253.1
NFKB activating protein
chr19_+_10086305 0.36 ENST00000253110.16
ENST00000591813.5
shiftless antiviral inhibitor of ribosomal frameshifting
chr10_+_69801874 0.36 ENST00000357811.8
collagen type XIII alpha 1 chain

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF6_IRF4_IRF5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.1 GO:0033606 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
1.5 13.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
1.3 3.9 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.8 2.5 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.8 2.3 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.6 1.7 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.5 3.8 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.5 5.5 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.5 2.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.5 5.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.4 1.3 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.4 1.2 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428)
0.4 1.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.4 1.1 GO:0060345 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.3 1.7 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.3 7.7 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.3 1.8 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.3 0.8 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.3 3.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 2.2 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.2 2.6 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.2 0.7 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.2 1.3 GO:1904383 response to sodium phosphate(GO:1904383)
0.2 0.6 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 1.3 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 1.1 GO:0006064 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) L-ascorbic acid biosynthetic process(GO:0019853) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
0.2 1.8 GO:0038183 bile acid signaling pathway(GO:0038183)
0.2 0.7 GO:0061360 optic nerve formation(GO:0021634) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.2 0.5 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.2 0.7 GO:0035498 carnosine metabolic process(GO:0035498)
0.2 0.8 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 0.5 GO:1904826 regulation of phenotypic switching by transcription from RNA polymerase II promoter(GO:0100057) regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.1 1.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 2.0 GO:0060982 coronary artery morphogenesis(GO:0060982)
0.1 0.4 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 3.0 GO:0006063 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585)
0.1 4.6 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 0.5 GO:0050822 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 1.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 4.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.3 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1 0.5 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 5.8 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.1 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.1 1.2 GO:0070673 response to interleukin-18(GO:0070673)
0.1 0.3 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 1.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 6.0 GO:0033198 response to ATP(GO:0033198)
0.1 1.3 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 0.5 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.3 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 1.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.2 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.3 GO:0090108 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.1 0.9 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.1 0.4 GO:0090155 negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 0.6 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.5 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 1.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 1.8 GO:0072643 interferon-gamma secretion(GO:0072643)
0.1 1.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.6 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.6 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 1.0 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 5.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.1 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.1 GO:1903989 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
0.1 0.3 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.3 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.2 GO:0033320 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.0 0.7 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 1.2 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.5 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 1.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 1.8 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.6 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 3.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.8 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.6 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.3 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.5 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 3.7 GO:0001895 retina homeostasis(GO:0001895)
0.0 1.0 GO:0001765 membrane raft assembly(GO:0001765)
0.0 0.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.7 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:1904796 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.0 0.1 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.5 GO:0019532 oxalate transport(GO:0019532)
0.0 0.4 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 1.7 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 2.3 GO:0070206 protein trimerization(GO:0070206)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.7 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.4 GO:0043383 negative T cell selection(GO:0043383)
0.0 3.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 1.5 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.5 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.9 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.3 GO:0001711 endodermal cell fate commitment(GO:0001711) histone H2B ubiquitination(GO:0033523)
0.0 0.0 GO:0006382 adenosine to inosine editing(GO:0006382) IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709) negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.2 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0019413 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:2001179 regulation of interleukin-10 secretion(GO:2001179) positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 1.6 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 1.3 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.4 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.5 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2 6.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 3.5 GO:0097433 dense body(GO:0097433)
0.2 0.9 GO:0097059 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.1 0.7 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.8 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.7 GO:0042825 TAP complex(GO:0042825)
0.1 1.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 4.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 2.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 5.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 2.3 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 2.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 15.8 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 7.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 1.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 1.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 8.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.1 GO:0005903 brush border(GO:0005903)
0.0 1.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.8 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.8 6.0 GO:0043208 glycosphingolipid binding(GO:0043208)
0.5 13.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.5 2.3 GO:0048030 disaccharide binding(GO:0048030)
0.4 3.9 GO:0015057 thrombin receptor activity(GO:0015057)
0.4 1.1 GO:0019808 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.4 1.1 GO:0097689 iron channel activity(GO:0097689)
0.3 3.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 1.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 1.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.7 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.2 0.6 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.2 2.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.2 1.2 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 2.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 1.8 GO:0038181 bile acid receptor activity(GO:0038181)
0.2 1.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.2 1.3 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.7 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 1.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.5 GO:0045569 TRAIL binding(GO:0045569)
0.1 4.5 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.5 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 0.4 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.1 0.9 GO:0004771 sterol esterase activity(GO:0004771)
0.1 6.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.9 GO:0042608 T cell receptor binding(GO:0042608)
0.1 1.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 1.7 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.3 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.1 0.9 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 1.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 6.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.6 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 2.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 3.0 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.3 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.6 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.5 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.7 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 1.4 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 1.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 4.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0016015 morphogen activity(GO:0016015)
0.0 0.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 9.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 1.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.5 GO:0032041 NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.0 GO:0004641 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.0 4.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.7 ST GA12 PATHWAY G alpha 12 Pathway
0.1 0.8 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 2.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 3.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 2.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 4.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 4.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 3.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 2.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 5.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.8 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 3.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 3.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 12.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 3.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 6.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 5.2 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 4.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 2.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.9 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 1.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI