ISMARA results: IRF9

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Illumina Body Map 2 (GSE30611)

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Results for IRF9

Z-value: 1.04

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Transcription factors associated with IRF9

Gene Symbol	Gene ID	Gene Info
IRF9 Ensembl NCBI GeneCards UniProt	ENSG00000213928.9	interferon regulatory factor 9

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
IRF9	hg38_v1_chr14_+_24161257_24161322	0.43	1.3e-02	Click!

Activity profile of IRF9 motif

Sorted Z-values of IRF9 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr14_+_22462932 Show fit	6.43	ENST00000390477.2	TRDC Ensembl NCBI GeneCards UniProt Show fit	T cell receptor delta constant
chr21_+_41361999 Show fit	5.80	ENST00000436410.5 ENST00000435611.6 ENST00000330714.8	MX2 Ensembl NCBI GeneCards UniProt Show fit	MX dynamin like GTPase 2
chr1_-_161631152 Show fit	5.06	ENST00000421702.3 ENST00000650385.1	FCGR3B Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG receptor IIIb
chr1_-_161631032 Show fit	5.01	ENST00000534776.1 ENST00000613418.4 ENST00000614870.4	FCGR3B Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG receptor IIIb
chr6_+_6588708 Show fit	4.58	ENST00000230568.5	LY86 Ensembl NCBI GeneCards UniProt Show fit	lymphocyte antigen 86
chr1_-_150765735 Show fit	4.49	ENST00000679898.1 ENST00000448301.7 ENST00000680664.1 ENST00000679512.1 ENST00000368985.8 ENST00000679582.1	CTSS Ensembl NCBI GeneCards UniProt Show fit	cathepsin S
chr1_-_150765785 Show fit	4.39	ENST00000680311.1 ENST00000681728.1 ENST00000680288.1	CTSS Ensembl NCBI GeneCards UniProt Show fit	cathepsin S
chr19_+_16143678 Show fit	4.15	ENST00000613986.4 ENST00000593031.1	HSH2D Ensembl NCBI GeneCards UniProt Show fit	hematopoietic SH2 domain containing
chr22_+_39901075 Show fit	3.90	ENST00000344138.9	GRAP2 Ensembl NCBI GeneCards UniProt Show fit	GRB2 related adaptor protein 2
chr6_-_24935942 Show fit	3.50	ENST00000645100.1 ENST00000643898.2 ENST00000613507.4	RIPOR2 Ensembl NCBI GeneCards UniProt Show fit	RHO family interacting cell polarization regulator 2
chr3_-_27722699 Show fit	3.16	ENST00000461503.2	EOMES Ensembl NCBI GeneCards UniProt Show fit	eomesodermin
chr17_+_6755834 Show fit	3.00	ENST00000346752.8	XAF1 Ensembl NCBI GeneCards UniProt Show fit	XIAP associated factor 1
chr12_+_112906949 Show fit	2.96	ENST00000679971.1 ENST00000675868.2 ENST00000550883.2 ENST00000553152.2 ENST00000202917.10 ENST00000679467.1 ENST00000680659.1 ENST00000540589.3 ENST00000552526.2 ENST00000681228.1 ENST00000680934.1 ENST00000681700.1 ENST00000679987.1	OAS1 Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 1
chrX_+_37780049 Show fit	2.79	ENST00000378588.5	CYBB Ensembl NCBI GeneCards UniProt Show fit	cytochrome b-245 beta chain
chr18_-_69956924 Show fit	2.53	ENST00000581982.5 ENST00000280200.8	CD226 Ensembl NCBI GeneCards UniProt Show fit	CD226 molecule
chr12_+_112907006 Show fit	2.51	ENST00000680455.1 ENST00000551241.6 ENST00000550689.2 ENST00000679841.1 ENST00000679494.1 ENST00000553185.2	OAS1 Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 1
chr21_+_41426590 Show fit	2.49	ENST00000679543.1 ENST00000680364.1	MX1 Ensembl NCBI GeneCards UniProt Show fit	MX dynamin like GTPase 1
chr6_+_106098933 Show fit	2.43	ENST00000369089.3	PRDM1 Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 1
chr12_-_121039236 Show fit	2.26	ENST00000257570.9	OASL Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase like
chr12_-_121039204 Show fit	2.17	ENST00000620239.5	OASL Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase like
chr13_-_40982880 Show fit	2.17	ENST00000635415.1	ELF1 Ensembl NCBI GeneCards UniProt Show fit	E74 like ETS transcription factor 1
chr1_+_241532121 Show fit	2.16	ENST00000366558.7	KMO Ensembl NCBI GeneCards UniProt Show fit	kynurenine 3-monooxygenase
chr4_-_76023489 Show fit	2.16	ENST00000306602.3	CXCL10 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 10
chr4_-_168480477 Show fit	2.14	ENST00000514748.5 ENST00000512371.1 ENST00000505890.5 ENST00000682922.1 ENST00000511577.5	DDX60L Ensembl NCBI GeneCards UniProt Show fit	DExD/H-box 60 like
chr2_-_151289613 Show fit	2.12	ENST00000243346.10	NMI Ensembl NCBI GeneCards UniProt Show fit	N-myc and STAT interactor
chrX_-_30577759 Show fit	2.06	ENST00000378962.4	TASL Ensembl NCBI GeneCards UniProt Show fit	TLR adaptor interacting with endolysosomal SLC15A4
chr21_+_41426168 Show fit	2.03	ENST00000681266.1 ENST00000417963.6	MX1 Ensembl NCBI GeneCards UniProt Show fit	MX dynamin like GTPase 1
chr17_+_80260826 Show fit	2.01	ENST00000508628.6 ENST00000582970.5 ENST00000319921.4	RNF213 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 213
chr21_+_41426031 Show fit	1.98	ENST00000455164.6 ENST00000681849.1 ENST00000679705.1 ENST00000424365.6	MX1 Ensembl NCBI GeneCards UniProt Show fit	MX dynamin like GTPase 1
chr12_-_121039156 Show fit	1.97	ENST00000339275.10	OASL Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase like
chr2_-_151289871 Show fit	1.97	ENST00000414946.1	NMI Ensembl NCBI GeneCards UniProt Show fit	N-myc and STAT interactor
chr12_+_112906777 Show fit	1.89	ENST00000452357.7 ENST00000445409.7	OAS1 Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 1
chr2_+_162318884 Show fit	1.89	ENST00000446271.5 ENST00000429691.6	GCA Ensembl NCBI GeneCards UniProt Show fit	grancalcin
chr15_+_44711487 Show fit	1.87	ENST00000544417.5 ENST00000559916.1 ENST00000648006.3	B2M Ensembl NCBI GeneCards UniProt Show fit	beta-2-microglobulin
chr3_-_121660892 Show fit	1.87	ENST00000428394.6 ENST00000314583.8	HCLS1 Ensembl NCBI GeneCards UniProt Show fit	hematopoietic cell-specific Lyn substrate 1
chr6_-_33314202 Show fit	1.86	ENST00000426633.6 ENST00000467025.1	TAPBP Ensembl NCBI GeneCards UniProt Show fit	TAP binding protein
chr17_+_27631148 Show fit	1.85	ENST00000313648.10 ENST00000395473.7 ENST00000577392.5 ENST00000584661.5	LGALS9 Ensembl NCBI GeneCards UniProt Show fit	galectin 9
chr21_+_41426232 Show fit	1.79	ENST00000398598.8 ENST00000681896.1 ENST00000680629.1 ENST00000680760.1 ENST00000680176.1 ENST00000680776.1 ENST00000681607.1 ENST00000680536.1	MX1 Ensembl NCBI GeneCards UniProt Show fit	MX dynamin like GTPase 1
chr12_+_112938422 Show fit	1.76	ENST00000680044.1 ENST00000680966.1 ENST00000548514.2 ENST00000681497.1 ENST00000551007.1 ENST00000228928.12 ENST00000680438.1 ENST00000681147.1 ENST00000679354.1 ENST00000681085.1 ENST00000680161.1	OAS3 Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 3
chr20_-_57620415 Show fit	1.73	ENST00000371173.8	ZBP1 Ensembl NCBI GeneCards UniProt Show fit	Z-DNA binding protein 1
chr21_+_41426197 Show fit	1.73	ENST00000680942.1 ENST00000288383.11 ENST00000679386.1	MX1 Ensembl NCBI GeneCards UniProt Show fit	MX dynamin like GTPase 1
chr21_+_41426289 Show fit	1.71	ENST00000679408.1 ENST00000681039.1 ENST00000681671.1	MX1 Ensembl NCBI GeneCards UniProt Show fit	MX dynamin like GTPase 1
chr20_-_57620467 Show fit	1.68	ENST00000395822.7	ZBP1 Ensembl NCBI GeneCards UniProt Show fit	Z-DNA binding protein 1
chr6_-_33314247 Show fit	1.67	ENST00000475304.5 ENST00000489157.5	TAPBP Ensembl NCBI GeneCards UniProt Show fit	TAP binding protein
chr1_+_241532370 Show fit	1.67	ENST00000366559.9 ENST00000366557.8	KMO Ensembl NCBI GeneCards UniProt Show fit	kynurenine 3-monooxygenase
chr1_+_66354375 Show fit	1.66	ENST00000480109.2	PDE4B Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 4B
chr12_-_121038967 Show fit	1.63	ENST00000680620.1 ENST00000679655.1 ENST00000543677.2	OASL Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase like
chr17_+_43211835 Show fit	1.61	ENST00000588693.5 ENST00000588659.5 ENST00000541594.5 ENST00000536052.5 ENST00000612339.4	TMEM106A Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 106A
chr8_+_27380629 Show fit	1.58	ENST00000412793.5	PTK2B Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine kinase 2 beta
chr6_-_33314055 Show fit	1.56	ENST00000434618.7	TAPBP Ensembl NCBI GeneCards UniProt Show fit	TAP binding protein
chr13_-_46387447 Show fit	1.56	ENST00000676051.1 ENST00000378787.7 ENST00000378781.7 ENST00000378797.6	RUBCNL Ensembl NCBI GeneCards UniProt Show fit	rubicon like autophagy enhancer
chr12_+_112938523 Show fit	1.56	ENST00000679483.1 ENST00000679493.1	OAS3 Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 3
chr18_-_69956670 Show fit	1.54	ENST00000583955.5	CD226 Ensembl NCBI GeneCards UniProt Show fit	CD226 molecule
chr13_-_42992165 Show fit	1.48	ENST00000398762.7 ENST00000313640.11 ENST00000313624.12	EPSTI1 Ensembl NCBI GeneCards UniProt Show fit	epithelial stromal interaction 1
chr10_-_89414458 Show fit	1.43	ENST00000371837.5	LIPA Ensembl NCBI GeneCards UniProt Show fit	lipase A, lysosomal acid type
chr1_+_78649818 Show fit	1.41	ENST00000370747.9 ENST00000438486.1	IFI44 Ensembl NCBI GeneCards UniProt Show fit	interferon induced protein 44
chr2_+_6877768 Show fit	1.38	ENST00000382040.4	RSAD2 Ensembl NCBI GeneCards UniProt Show fit	radical S-adenosyl methionine domain containing 2
chr14_-_67515153 Show fit	1.35	ENST00000555994.6	TMEM229B Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 229B
chr6_-_32838727 Show fit	1.35	ENST00000652259.1 ENST00000374897.4 ENST00000620123.4 ENST00000452392.2	TAP2 Ensembl NCBI GeneCards UniProt Show fit ENSG00000250264.1 Ensembl NCBI GeneCards UniProt Show fit	transporter 2, ATP binding cassette subfamily B member novel protein, TAP2-HLA-DOB readthrough
chr3_-_71360753 Show fit	1.32	ENST00000648783.1	FOXP1 Ensembl NCBI GeneCards UniProt Show fit	forkhead box P1
chr11_-_4393650 Show fit	1.26	ENST00000254436.8	TRIM21 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 21
chr12_-_56360084 Show fit	1.26	ENST00000314128.9 ENST00000557235.5 ENST00000651915.1	STAT2 Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 2
chr11_-_615570 Show fit	1.25	ENST00000649187.1 ENST00000647801.1 ENST00000397566.5 ENST00000397570.5	IRF7 Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 7
chr17_+_6756035 Show fit	1.24	ENST00000361842.8 ENST00000574907.5	XAF1 Ensembl NCBI GeneCards UniProt Show fit	XIAP associated factor 1
chr16_-_74700786 Show fit	1.20	ENST00000306247.11 ENST00000575686.1	MLKL Ensembl NCBI GeneCards UniProt Show fit	mixed lineage kinase domain like pseudokinase
chr2_-_6865901 Show fit	1.19	ENST00000256722.10	CMPK2 Ensembl NCBI GeneCards UniProt Show fit	cytidine/uridine monophosphate kinase 2
chr11_-_57567260 Show fit	1.15	ENST00000526659.1 ENST00000527022.1	UBE2L6 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 L6
chr6_-_33314386 Show fit	1.15	ENST00000456592.3	TAPBP Ensembl NCBI GeneCards UniProt Show fit	TAP binding protein
chr18_-_69957176 Show fit	1.13	ENST00000580335.1	CD226 Ensembl NCBI GeneCards UniProt Show fit	CD226 molecule
chr9_-_32526185 Show fit	1.10	ENST00000379883.3 ENST00000379868.6 ENST00000679859.1	DDX58 Ensembl NCBI GeneCards UniProt Show fit	DExD/H-box helicase 58
chr3_+_122564327 Show fit	1.10	ENST00000296161.9 ENST00000383661.3	DTX3L Ensembl NCBI GeneCards UniProt Show fit	deltex E3 ubiquitin ligase 3L
chr13_-_46387724 Show fit	1.10	ENST00000675585.1	RUBCNL Ensembl NCBI GeneCards UniProt Show fit	rubicon like autophagy enhancer
chr15_-_44711306 Show fit	1.10	ENST00000682850.1	PATL2 Ensembl NCBI GeneCards UniProt Show fit	PAT1 homolog 2
chr1_-_154608140 Show fit	1.08	ENST00000529168.2 ENST00000368474.9 ENST00000680305.1 ENST00000648231.2	ADAR Ensembl NCBI GeneCards UniProt Show fit	adenosine deaminase RNA specific
chr17_-_56914032 Show fit	1.06	ENST00000537230.3 ENST00000316881.9	TRIM25 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 25
chr3_-_122564232 Show fit	1.04	ENST00000471785.5 ENST00000466126.1	PARP9 Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 9
chr3_+_187368367 Show fit	1.03	ENST00000259030.3	RTP4 Ensembl NCBI GeneCards UniProt Show fit	receptor transporter protein 4
chr11_+_5624987 Show fit	1.03	ENST00000429814.3	TRIM34 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 34
chr9_-_83978429 Show fit	1.02	ENST00000351839.7	HNRNPK Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein K
chr12_+_6772512 Show fit	1.00	ENST00000441671.6 ENST00000203629.3	LAG3 Ensembl NCBI GeneCards UniProt Show fit	lymphocyte activating 3
chr1_+_159010002 Show fit	0.99	ENST00000359709.7	IFI16 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma inducible protein 16
chr1_+_154405193 Show fit	0.97	ENST00000622330.4 ENST00000344086.8	IL6R Ensembl NCBI GeneCards UniProt Show fit	interleukin 6 receptor
chr10_+_89414729 Show fit	0.97	ENST00000681163.1 ENST00000681348.1	IFIT5 Ensembl NCBI GeneCards UniProt Show fit	interferon induced protein with tetratricopeptide repeats 5
chr17_-_76493133 Show fit	0.96	ENST00000585701.5 ENST00000591192.1 ENST00000589526.5	RHBDF2 Ensembl NCBI GeneCards UniProt Show fit	rhomboid 5 homolog 2
chr7_+_18496269 Show fit	0.94	ENST00000432645.6	HDAC9 Ensembl NCBI GeneCards UniProt Show fit	histone deacetylase 9
chr3_-_142448028 Show fit	0.94	ENST00000392981.7	XRN1 Ensembl NCBI GeneCards UniProt Show fit	5'-3' exoribonuclease 1
chr14_+_24161257 Show fit	0.94	ENST00000396864.8 ENST00000557894.5 ENST00000559284.5 ENST00000560275.5	IRF9 Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 9
chr10_+_89301932 Show fit	0.93	ENST00000371826.4 ENST00000679755.1	IFIT2 Ensembl NCBI GeneCards UniProt Show fit	interferon induced protein with tetratricopeptide repeats 2
chr3_-_71581540 Show fit	0.91	ENST00000650068.1	FOXP1 Ensembl NCBI GeneCards UniProt Show fit	forkhead box P1
chr1_+_220879434 Show fit	0.87	ENST00000366903.8	HLX Ensembl NCBI GeneCards UniProt Show fit	H2.0 like homeobox
chr3_-_122564253 Show fit	0.86	ENST00000492382.5 ENST00000682323.1 ENST00000462315.5	PARP9 Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 9
chr14_+_100065400 Show fit	0.86	ENST00000555706.5 ENST00000392920.8 ENST00000555048.5	EVL Ensembl NCBI GeneCards UniProt Show fit	Enah/Vasp-like
chr1_+_1013485 Show fit	0.86	ENST00000649529.1	ISG15 Ensembl NCBI GeneCards UniProt Show fit	ISG15 ubiquitin like modifier
chr3_+_63911929 Show fit	0.85	ENST00000487717.5	ATXN7 Ensembl NCBI GeneCards UniProt Show fit	ataxin 7
chr20_-_57620393 Show fit	0.85	ENST00000541799.1	ZBP1 Ensembl NCBI GeneCards UniProt Show fit	Z-DNA binding protein 1
chr1_+_112674416 Show fit	0.84	ENST00000413052.6 ENST00000369645.5	MOV10 Ensembl NCBI GeneCards UniProt Show fit	Mov10 RISC complex RNA helicase
chr7_-_140062841 Show fit	0.84	ENST00000263549.8	PARP12 Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 12
chr11_-_615921 Show fit	0.79	ENST00000348655.11 ENST00000525445.6 ENST00000330243.9	IRF7 Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 7
chr17_+_6755559 Show fit	0.79	ENST00000574394.5	XAF1 Ensembl NCBI GeneCards UniProt Show fit	XIAP associated factor 1
chr6_+_20401864 Show fit	0.77	ENST00000346618.8 ENST00000613242.4	E2F3 Ensembl NCBI GeneCards UniProt Show fit	E2F transcription factor 3
chr1_+_159009886 Show fit	0.76	ENST00000340979.10 ENST00000368131.8 ENST00000295809.12 ENST00000368132.7	IFI16 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma inducible protein 16
chr11_-_57567617 Show fit	0.76	ENST00000287156.9	UBE2L6 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 L6
chr3_-_142448060 Show fit	0.75	ENST00000264951.8	XRN1 Ensembl NCBI GeneCards UniProt Show fit	5'-3' exoribonuclease 1
chr7_+_135148041 Show fit	0.73	ENST00000275767.3	TMEM140 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 140
chr4_-_146521666 Show fit	0.71	ENST00000507030.5	SLC10A7 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 10 member 7
chr6_-_81752671 Show fit	0.70	ENST00000320172.11 ENST00000369754.7 ENST00000369756.3	TENT5A Ensembl NCBI GeneCards UniProt Show fit	terminal nucleotidyltransferase 5A
chr15_-_25863304 Show fit	0.70	ENST00000555815.6 ENST00000673716.1	ATP10A Ensembl NCBI GeneCards UniProt Show fit	ATPase phospholipid transporting 10A (putative)
chr12_+_112938284 Show fit	0.69	ENST00000681346.1	OAS3 Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 3
chr20_-_49278034 Show fit	0.67	ENST00000371744.5 ENST00000396105.6 ENST00000371752.5	ZNFX1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger NFX1-type containing 1
chr14_-_56810448 Show fit	0.66	ENST00000339475.10 ENST00000555006.5 ENST00000672264.2 ENST00000554559.5 ENST00000555804.1	OTX2 Ensembl NCBI GeneCards UniProt Show fit	orthodenticle homeobox 2
chr5_+_134526100 Show fit	0.63	ENST00000395003.5	JADE2 Ensembl NCBI GeneCards UniProt Show fit	jade family PHD finger 2
chr3_+_122680802 Show fit	0.61	ENST00000474629.7	PARP14 Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 14
chr14_-_56810380 Show fit	0.61	ENST00000672125.1 ENST00000673481.1	OTX2 Ensembl NCBI GeneCards UniProt Show fit	orthodenticle homeobox 2
chr10_+_89414555 Show fit	0.59	ENST00000371795.5 ENST00000681422.1	IFIT5 Ensembl NCBI GeneCards UniProt Show fit	interferon induced protein with tetratricopeptide repeats 5
chr3_-_146544538 Show fit	0.55	ENST00000462666.5	PLSCR1 Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chrX_-_40097403 Show fit	0.54	ENST00000397354.7	BCOR Ensembl NCBI GeneCards UniProt Show fit	BCL6 corepressor
chr8_-_143986425 Show fit	0.53	ENST00000313059.9 ENST00000524918.5 ENST00000313028.12 ENST00000525773.5	PARP10 Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 10
chr3_-_122564577 Show fit	0.51	ENST00000477522.6 ENST00000360356.6	PARP9 Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 9
chr10_-_93482287 Show fit	0.51	ENST00000371489.5	MYOF Ensembl NCBI GeneCards UniProt Show fit	myoferlin
chr2_+_6865557 Show fit	0.49	ENST00000680607.1 ENST00000680320.1 ENST00000442639.6	RSAD2 Ensembl NCBI GeneCards UniProt Show fit	radical S-adenosyl methionine domain containing 2
chr3_+_122680850 Show fit	0.49	ENST00000494811.2	PARP14 Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 14
chr2_-_37156942 Show fit	0.48	ENST00000680273.1 ENST00000233057.9 ENST00000679979.1 ENST00000679507.1 ENST00000681463.1 ENST00000395127.6	EIF2AK2 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2 alpha kinase 2
chr3_+_63912588 Show fit	0.47	ENST00000522345.2	ATXN7 Ensembl NCBI GeneCards UniProt Show fit	ataxin 7
chr2_+_33476640 Show fit	0.46	ENST00000425210.5 ENST00000444784.5 ENST00000423159.5 ENST00000403687.8	RASGRP3 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 3
chr16_-_15643024 Show fit	0.45	ENST00000540441.6	MARF1 Ensembl NCBI GeneCards UniProt Show fit	meiosis regulator and mRNA stability factor 1
chr1_+_112674649 Show fit	0.45	ENST00000369644.5	MOV10 Ensembl NCBI GeneCards UniProt Show fit	Mov10 RISC complex RNA helicase
chr13_+_49495941 Show fit	0.45	ENST00000378319.8 ENST00000496623.5 ENST00000426879.5	PHF11 Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 11
chr20_-_49278416 Show fit	0.42	ENST00000371754.8	ZNFX1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger NFX1-type containing 1
chr20_+_62804794 Show fit	0.42	ENST00000290291.10	OGFR Ensembl NCBI GeneCards UniProt Show fit	opioid growth factor receptor
chr19_+_10111689 Show fit	0.39	ENST00000321826.5	P2RY11 Ensembl NCBI GeneCards UniProt Show fit	purinergic receptor P2Y11
chr13_+_49496355 Show fit	0.39	ENST00000496612.5 ENST00000357596.7 ENST00000485919.5 ENST00000442195.5	PHF11 Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 11
chr3_-_146544701 Show fit	0.37	ENST00000487389.5	PLSCR1 Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chr1_+_112674722 Show fit	0.37	ENST00000357443.2	MOV10 Ensembl NCBI GeneCards UniProt Show fit	Mov10 RISC complex RNA helicase
chr4_-_146521830 Show fit	0.35	ENST00000511374.5	SLC10A7 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 10 member 7
chr3_-_179451387 Show fit	0.34	ENST00000675901.1 ENST00000232564.8 ENST00000674862.1 ENST00000497513.1	GNB4 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit beta 4
chr1_-_182589239 Show fit	0.34	ENST00000367559.7 ENST00000539397.1	RNASEL Ensembl NCBI GeneCards UniProt Show fit	ribonuclease L
chr11_-_60952559 Show fit	0.34	ENST00000538739.2	SLC15A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 15 member 3
chr15_+_58410543 Show fit	0.34	ENST00000356113.10 ENST00000414170.7	LIPC Ensembl NCBI GeneCards UniProt Show fit	lipase C, hepatic type
chr2_-_37157093 Show fit	0.34	ENST00000681507.1	EIF2AK2 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2 alpha kinase 2
chr18_+_3262956 Show fit	0.33	ENST00000584539.1	MYL12B Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 12B
chr10_-_5978022 Show fit	0.31	ENST00000525219.6	IL15RA Ensembl NCBI GeneCards UniProt Show fit	interleukin 15 receptor subunit alpha
chr3_-_146544850 Show fit	0.31	ENST00000472349.1	PLSCR1 Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chr3_-_142448004 Show fit	0.31	ENST00000463916.5	XRN1 Ensembl NCBI GeneCards UniProt Show fit	5'-3' exoribonuclease 1
chr16_+_28950807 Show fit	0.29	ENST00000564978.5 ENST00000320805.8	NFATC2IP Ensembl NCBI GeneCards UniProt Show fit	nuclear factor of activated T cells 2 interacting protein
chr11_-_60952134 Show fit	0.29	ENST00000679573.1 ENST00000681882.1 ENST00000681951.1 ENST00000227880.8	SLC15A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 15 member 3
chr10_-_93482194 Show fit	0.28	ENST00000358334.9 ENST00000371488.3	MYOF Ensembl NCBI GeneCards UniProt Show fit	myoferlin
chr3_-_146544578 Show fit	0.28	ENST00000342435.9 ENST00000448787.6	PLSCR1 Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chr19_+_17405685 Show fit	0.28	ENST00000646744.1 ENST00000635536.2 ENST00000635060.2 ENST00000634291.2 ENST00000645298.1 ENST00000528911.5	BISPR Ensembl NCBI GeneCards UniProt Show fit MVB12A Ensembl NCBI GeneCards UniProt Show fit	BST2 interferon stimulated positive regulator multivesicular body subunit 12A
chr3_-_146544636 Show fit	0.25	ENST00000486631.5	PLSCR1 Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chr10_-_93482326 Show fit	0.25	ENST00000359263.9	MYOF Ensembl NCBI GeneCards UniProt Show fit	myoferlin
chr2_-_6865655 Show fit	0.24	ENST00000404168.1	CMPK2 Ensembl NCBI GeneCards UniProt Show fit	cytidine/uridine monophosphate kinase 2
chr8_-_28083850 Show fit	0.23	ENST00000418860.1	NUGGC Ensembl NCBI GeneCards UniProt Show fit	nuclear GTPase, germinal center associated
chr9_+_99906646 Show fit	0.23	ENST00000259400.11 ENST00000531035.5 ENST00000525640.5 ENST00000534052.1 ENST00000526607.1	STX17 Ensembl NCBI GeneCards UniProt Show fit	syntaxin 17
chr17_-_4263847 Show fit	0.19	ENST00000570535.5 ENST00000574367.5 ENST00000341657.9	ANKFY1 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and FYVE domain containing 1
chr2_+_33476616 Show fit	0.18	ENST00000442390.5	RASGRP3 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 3
chr7_-_84492718 Show fit	0.18	ENST00000424555.5	SEMA3A Ensembl NCBI GeneCards UniProt Show fit	semaphorin 3A
chr2_-_6865799 Show fit	0.18	ENST00000458098.5	CMPK2 Ensembl NCBI GeneCards UniProt Show fit	cytidine/uridine monophosphate kinase 2
chr17_+_56153458 Show fit	0.17	ENST00000318698.6 ENST00000682825.1 ENST00000566473.6	ANKFN1 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and fibronectin type III domain containing 1
chr10_+_89332484 Show fit	0.15	ENST00000371811.4 ENST00000680037.1 ENST00000679583.1 ENST00000679897.1	IFIT3 Ensembl NCBI GeneCards UniProt Show fit	interferon induced protein with tetratricopeptide repeats 3
chr2_+_6933043 Show fit	0.15	ENST00000416587.5	RNF144A Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 144A
chr3_-_28348436 Show fit	0.13	ENST00000415852.1	AZI2 Ensembl NCBI GeneCards UniProt Show fit	5-azacytidine induced 2
chr6_-_117573571 Show fit	0.12	ENST00000467125.1	ENSG00000282218.1 Ensembl NCBI GeneCards UniProt Show fit	novel protein, GOPC-ROS1 readthrough
chr19_+_17405734 Show fit	0.09	ENST00000635572.1 ENST00000634675.1 ENST00000634813.1 ENST00000647283.1 ENST00000635435.2 ENST00000634731.2 ENST00000635339.1 ENST00000528604.5	BISPR Ensembl NCBI GeneCards UniProt Show fit MVB12A Ensembl NCBI GeneCards UniProt Show fit	BST2 interferon stimulated positive regulator multivesicular body subunit 12A
chr11_+_67022719 Show fit	0.06	ENST00000525457.5	SYT12 Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin 12
chr6_+_37433197 Show fit	0.06	ENST00000455891.5 ENST00000373451.9	CMTR1 Ensembl NCBI GeneCards UniProt Show fit	cap methyltransferase 1
chr7_-_105691637 Show fit	0.05	ENST00000472195.1	ATXN7L1 Ensembl NCBI GeneCards UniProt Show fit	ataxin 7 like 1
chr11_-_86672328 Show fit	0.04	ENST00000526834.1 ENST00000323418.10	ME3 Ensembl NCBI GeneCards UniProt Show fit	malic enzyme 3
chr16_-_11256192 Show fit	0.03	ENST00000644787.1 ENST00000332029.4	SOCS1 Ensembl NCBI GeneCards UniProt Show fit	suppressor of cytokine signaling 1
chr3_-_167734510 Show fit	0.03	ENST00000475915.6 ENST00000462725.6 ENST00000461494.5	PDCD10 Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 10
chr16_-_28506826 Show fit	0.01	ENST00000356897.1	IL27 Ensembl NCBI GeneCards UniProt Show fit	interleukin 27

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF9

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.0	8.9	GO:0034769	basement membrane disassembly(GO:0034769)
1.6	6.2	GO:0050823	peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
1.1	3.2	GO:0002428	antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428)
1.1	3.2	GO:0002302	CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.0	4.1	GO:1902524	negative regulation of interferon-alpha biosynthetic process(GO:0045355) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.9	2.8	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.9	5.2	GO:0002729	positive regulation of natural killer cell cytokine production(GO:0002729)
0.8	2.4	GO:1990654	sebum secreting cell proliferation(GO:1990654)
0.8	3.8	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.7	17.5	GO:0003373	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.6	1.9	GO:2000562	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.6	3.5	GO:2001107	negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.5	4.6	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.4	2.0	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.4	2.0	GO:0071409	cellular response to cycloheximide(GO:0071409)
0.4	4.1	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.3	1.6	GO:0006233	dUDP biosynthetic process(GO:0006227) dTDP biosynthetic process(GO:0006233) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dTDP metabolic process(GO:0046072) dUDP metabolic process(GO:0046077)
0.3	1.6	GO:2000538	regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.3	1.3	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.3	1.9	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.3	4.0	GO:0060700	regulation of ribonuclease activity(GO:0060700)
0.3	2.0	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.3	1.1	GO:0010607	negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.3	0.8	GO:0051805	evasion or tolerance of host immune response(GO:0020012) evasion or tolerance of host defense response(GO:0030682) evasion or tolerance by virus of host immune response(GO:0030683) evasion or tolerance of immune response of other organism involved in symbiotic interaction(GO:0051805) evasion or tolerance of defense response of other organism involved in symbiotic interaction(GO:0051807)
0.3	2.9	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.2	1.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.2	22.6	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.2	1.0	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.2	1.0	GO:0002384	hepatic immune response(GO:0002384)
0.2	2.2	GO:0010819	regulation of T cell chemotaxis(GO:0010819)
0.2	1.7	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1	1.5	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.9	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1	2.2	GO:0032625	interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1	1.3	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	0.5	GO:0000415	negative regulation of histone H3-K36 methylation(GO:0000415)
0.1	1.9	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	1.7	GO:1901898	neutrophil homeostasis(GO:0001780) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1	3.1	GO:0035456	response to interferon-beta(GO:0035456)
0.1	10.1	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.1	0.8	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.1	6.4	GO:0006910	phagocytosis, recognition(GO:0006910)
0.1	1.3	GO:2000543	positive regulation of gastrulation(GO:2000543)
0.1	1.1	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.1	2.2	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	1.0	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.9	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.1	1.1	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production(GO:0032725)
0.0	0.2	GO:0016240	autophagosome docking(GO:0016240)
0.0	1.1	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.0	0.9	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.0	0.2	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.0	0.6	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	3.9	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0	1.4	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	1.2	GO:0070207	protein homotrimerization(GO:0070207)
0.0	1.0	GO:0070206	protein trimerization(GO:0070206)
0.0	0.4	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.0	0.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	1.3	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.0	1.1	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	2.9	GO:0032481	positive regulation of type I interferon production(GO:0032481)
0.0	0.1	GO:0036451	cap mRNA methylation(GO:0036451)
0.0	0.4	GO:0023041	neuronal signal transduction(GO:0023041)
0.0	0.7	GO:0045332	phospholipid translocation(GO:0045332)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	8.9	GO:0036021	endolysosome lumen(GO:0036021)
1.1	7.6	GO:0042825	TAP complex(GO:0042825)
0.4	1.9	GO:0031905	early endosome lumen(GO:0031905)
0.3	3.5	GO:0060171	stereocilium membrane(GO:0060171)
0.2	1.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	2.8	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	1.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	6.4	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.1	1.6	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	1.6	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	1.7	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	5.8	GO:0005643	nuclear pore(GO:0005643)
0.0	9.9	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.2	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	6.0	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	8.4	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	5.7	GO:0005741	mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0	10.6	GO:0031965	nuclear membrane(GO:0031965)
0.0	0.2	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	3.9	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	1.0	GO:0002102	podosome(GO:0002102)
0.0	1.9	GO:0035578	azurophil granule lumen(GO:0035578)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	7.6	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433)
1.4	4.3	GO:0003692	left-handed Z-DNA binding(GO:0003692)
1.2	19.4	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.6	10.1	GO:0019864	IgG binding(GO:0019864)
0.5	1.6	GO:0033862	UMP kinase activity(GO:0033862)
0.4	2.2	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.4	1.9	GO:0048030	disaccharide binding(GO:0048030)
0.3	2.0	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.3	1.6	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3	3.8	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.2	1.0	GO:0070119	ciliary neurotrophic factor binding(GO:0070119)
0.2	8.9	GO:0001968	fibronectin binding(GO:0001968)
0.2	1.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2	1.4	GO:0004771	sterol esterase activity(GO:0004771)
0.2	1.5	GO:0042296	ISG15 transferase activity(GO:0042296)
0.1	2.8	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.1	1.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.1	1.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.8	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1	4.9	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	6.4	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.1	1.1	GO:0031386	protein tag(GO:0031386)
0.1	1.8	GO:0042609	CD4 receptor binding(GO:0042609)
0.1	1.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	8.0	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	1.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	3.5	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.3	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	1.6	GO:0000339	RNA cap binding(GO:0000339)
0.0	2.4	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	1.9	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.9	GO:0005522	profilin binding(GO:0005522)
0.0	17.5	GO:0003924	GTPase activity(GO:0003924)
0.0	3.1	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	4.1	GO:0043621	protein self-association(GO:0043621)
0.0	0.9	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.4	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	1.7	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.4	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.7	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0	0.3	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.4	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	1.9	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.3	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	2.6	GO:0004386	helicase activity(GO:0004386)
0.0	3.6	GO:0001047	core promoter binding(GO:0001047)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	3.9	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	1.0	ST STAT3 PATHWAY	STAT3 Pathway
0.1	5.0	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	2.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	1.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	2.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	2.8	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	8.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.9	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.8	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	1.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	1.1	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.8	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	1.0	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	2.0	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	10.7	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.4	48.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.2	2.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	1.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.1	1.0	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	4.8	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	2.0	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	2.6	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	1.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	0.8	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	2.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	5.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	1.6	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	2.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	4.6	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	1.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.5	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases

Results for IRF9

Z-value: 1.04

Motif logo

Transcription factors associated with IRF9

Activity-expression correlation:

Activity profile of IRF9 motif

Sorted Z-values of IRF9 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF9

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: