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Illumina Body Map 2 (GSE30611)

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Results for IRX3

Z-value: 1.55

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Transcription factors associated with IRX3

Gene Symbol Gene ID Gene Info
ENSG00000177508.12 iroquois homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX3hg38_v1_chr16_-_54286763_542868030.163.8e-01Click!

Activity profile of IRX3 motif

Sorted Z-values of IRX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_55024250 8.44 ENST00000231009.3
granzyme K
chr1_+_26317950 7.19 ENST00000374213.3
CD52 molecule
chr13_-_46142834 7.18 ENST00000674665.1
lymphocyte cytosolic protein 1
chr1_+_116754422 5.98 ENST00000369478.4
ENST00000369477.1
CD2 molecule
chr2_+_89936859 5.65 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr14_-_106038355 5.49 ENST00000390597.3
immunoglobulin heavy variable 2-5
chr2_-_89222461 5.14 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr14_-_106470788 4.54 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr2_-_136118142 4.23 ENST00000241393.4
C-X-C motif chemokine receptor 4
chr14_-_105987068 4.20 ENST00000390594.3
immunoglobulin heavy variable 1-2
chr14_-_106374129 4.07 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr4_+_70226116 3.78 ENST00000317987.6
follicular dendritic cell secreted protein
chr14_-_106012390 3.76 ENST00000455737.2
immunoglobulin heavy variable 4-4
chr14_-_106511856 3.75 ENST00000390622.2
immunoglobulin heavy variable 1-46
chr14_-_106154113 3.65 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr15_-_21742799 3.46 ENST00000622410.2
novel protein, identical to IGHV4-4
chr6_-_49866527 3.39 ENST00000335847.9
cysteine rich secretory protein 1
chr14_-_106349792 3.36 ENST00000438142.3
immunoglobulin heavy variable 4-31
chr22_+_22811737 3.36 ENST00000390315.3
immunoglobulin lambda variable 3-10
chr5_+_35856883 3.26 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr14_-_106185387 3.18 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr14_-_106269133 3.09 ENST00000390609.3
immunoglobulin heavy variable 3-23
chr2_-_157444044 3.08 ENST00000264192.8
cytohesin 1 interacting protein
chr1_+_196819731 3.07 ENST00000320493.10
ENST00000367424.4
complement factor H related 1
chr14_-_106005574 3.05 ENST00000390595.3
immunoglobulin heavy variable 1-3
chr14_-_106235582 3.03 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr6_-_49866453 2.99 ENST00000507853.5
cysteine rich secretory protein 1
chr7_-_38249572 2.93 ENST00000436911.6
T cell receptor gamma constant 2
chr14_+_21918161 2.88 ENST00000390439.2
T cell receptor alpha variable 13-2
chr2_-_89245596 2.85 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr22_+_22818994 2.80 ENST00000390316.2
immunoglobulin lambda variable 3-9
chr14_-_106811131 2.79 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr16_+_72056153 2.69 ENST00000576168.6
ENST00000567185.7
ENST00000567612.2
haptoglobin
chr4_-_38782970 2.67 ENST00000502321.5
ENST00000308973.9
ENST00000613579.4
ENST00000361424.6
ENST00000622002.4
toll like receptor 10
chr5_-_156963222 2.64 ENST00000407087.4
ENST00000274532.7
T cell immunoglobulin and mucin domain containing 4
chr17_-_31314040 2.61 ENST00000330927.5
ecotropic viral integration site 2B
chr6_-_107824294 2.61 ENST00000369020.8
ENST00000369022.6
Scm polycomb group protein like 4
chr10_+_88759997 2.56 ENST00000404459.2
lipase family member N
chr12_-_10098977 2.55 ENST00000315330.8
ENST00000457018.6
C-type lectin domain family 1 member A
chr1_+_207104226 2.53 ENST00000367070.8
complement component 4 binding protein alpha
chr8_-_100712761 2.53 ENST00000517403.5
poly(A) binding protein cytoplasmic 1
chr14_-_106579223 2.51 ENST00000390626.2
immunoglobulin heavy variable 5-51
chr17_-_31314066 2.46 ENST00000577894.1
ecotropic viral integration site 2B
chr22_+_39901075 2.43 ENST00000344138.9
GRB2 related adaptor protein 2
chr1_+_158289916 2.43 ENST00000368170.8
CD1c molecule
chr11_-_118342691 2.42 ENST00000300692.9
CD3d molecule
chr5_+_93583212 2.40 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chr1_-_160523204 2.39 ENST00000368055.1
ENST00000368057.8
ENST00000368059.7
SLAM family member 6
chr16_-_55833186 2.36 ENST00000361503.8
ENST00000422046.6
carboxylesterase 1
chr15_-_22185402 2.35 ENST00000557788.2
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr12_+_69348372 2.31 ENST00000261267.7
ENST00000549690.1
ENST00000548839.1
lysozyme
chr12_-_10390023 2.24 ENST00000240618.11
killer cell lectin like receptor K1
chr5_-_156935656 2.24 ENST00000406964.5
T cell immunoglobulin and mucin domain containing 4
chr14_-_106803221 2.23 ENST00000390636.2
immunoglobulin heavy variable 3-73
chr14_-_106771020 2.22 ENST00000617374.2
immunoglobulin heavy variable 2-70
chr12_+_5432101 2.22 ENST00000423158.4
neurotrophin 3
chr2_+_90004792 2.21 ENST00000462693.1
immunoglobulin kappa variable 2D-24 (non-functional)
chr14_-_106324743 2.20 ENST00000390612.3
immunoglobulin heavy variable 4-28
chr11_-_102874974 2.20 ENST00000571244.3
matrix metallopeptidase 12
chr4_+_89894846 2.20 ENST00000264790.7
multimerin 1
chr1_+_158845798 2.19 ENST00000438394.1
myeloid cell nuclear differentiation antigen
chr15_+_88635626 2.17 ENST00000379224.10
interferon stimulated exonuclease gene 20
chr1_+_160739286 2.17 ENST00000359331.8
ENST00000495334.1
SLAM family member 7
chr14_-_106593319 2.15 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr11_-_118342645 2.15 ENST00000529594.5
CD3d molecule
chr2_+_90038848 2.14 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr10_-_95069489 2.14 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
cytochrome P450 family 2 subfamily C member 8
chr11_-_118225002 2.14 ENST00000356289.10
ENST00000526620.5
junction adhesion molecule like
chr9_+_102995308 2.12 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
cylicin 2
chr2_+_90021567 2.10 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr5_-_56233287 2.07 ENST00000513241.2
ENST00000341048.9
ankyrin repeat domain 55
chr1_+_160739265 2.04 ENST00000368042.7
SLAM family member 7
chr7_+_142618821 2.03 ENST00000390393.3
T cell receptor beta variable 19
chr15_+_37934626 2.03 ENST00000559502.5
ENST00000558148.5
ENST00000319669.5
ENST00000558158.5
transmembrane and coiled-coil domains 5A
chr11_-_118342616 2.00 ENST00000392884.2
CD3d molecule
chr3_+_122325237 1.95 ENST00000264474.4
ENST00000479204.1
cystatin A
chr2_-_89177160 1.94 ENST00000484817.1
immunoglobulin kappa variable 2-24
chr11_+_60971668 1.90 ENST00000313421.11
CD6 molecule
chr1_+_160739239 1.89 ENST00000368043.8
SLAM family member 7
chr22_+_36863091 1.88 ENST00000650698.1
neutrophil cytosolic factor 4
chr11_+_60971777 1.88 ENST00000542157.5
ENST00000433107.6
ENST00000352009.9
ENST00000452451.6
CD6 molecule
chr6_-_32192630 1.84 ENST00000375040.8
G protein signaling modulator 3
chr15_+_80933358 1.83 ENST00000560027.1
cell migration inducing hyaluronidase 1
chr10_-_88952763 1.83 ENST00000224784.10
actin alpha 2, smooth muscle
chr4_+_73740541 1.80 ENST00000401931.1
ENST00000307407.8
C-X-C motif chemokine ligand 8
chr13_+_112376341 1.80 ENST00000414180.5
ENST00000283550.8
ENST00000443541.5
sperm acrosome associated 7
chr17_+_36103819 1.79 ENST00000615863.2
ENST00000621626.1
C-C motif chemokine ligand 4
chr6_-_24798907 1.77 ENST00000565469.4
armadillo like helical domain containing 2
chr16_+_85899121 1.76 ENST00000268638.10
ENST00000565552.1
interferon regulatory factor 8
chr7_-_41703062 1.75 ENST00000242208.5
inhibin subunit beta A
chr14_+_66486356 1.75 ENST00000636229.1
coiled-coil domain containing 196
chr2_+_188974364 1.74 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr1_+_206897435 1.74 ENST00000391929.7
ENST00000294984.7
ENST00000611909.4
ENST00000367093.3
interleukin 24
chr3_+_111911604 1.73 ENST00000495180.1
pleckstrin homology like domain family B member 2
chr2_-_88992903 1.73 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr11_+_57597563 1.71 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr14_+_94581407 1.67 ENST00000553511.1
ENST00000329597.12
ENST00000554633.5
ENST00000555681.1
ENST00000554276.1
serpin family A member 5
chr2_+_118942290 1.66 ENST00000412481.1
macrophage receptor with collagenous structure
chr5_+_160421847 1.66 ENST00000352433.10
ENST00000517480.1
ENST00000520452.5
ENST00000393964.1
PTTG1 regulator of sister chromatid separation, securin
chr12_-_9733292 1.66 ENST00000621400.4
ENST00000327839.3
C-type lectin like 1
chr6_-_32666648 1.65 ENST00000399082.7
ENST00000399079.7
ENST00000374943.8
ENST00000434651.6
major histocompatibility complex, class II, DQ beta 1
chr16_+_56961942 1.65 ENST00000200676.8
ENST00000566128.1
cholesteryl ester transfer protein
chr19_-_54463762 1.65 ENST00000611161.2
leukocyte receptor cluster member 9
chr1_-_19979607 1.65 ENST00000400520.8
ENST00000482011.2
ENST00000649436.1
phospholipase A2 group IIA
chr7_+_139829242 1.61 ENST00000455353.6
ENST00000458722.6
ENST00000448866.7
ENST00000411653.6
thromboxane A synthase 1
chr11_-_5254741 1.61 ENST00000444587.1
ENST00000336906.6
ENST00000642908.1
ENST00000647543.1
hemoglobin subunit gamma 2
novel protein
chr1_+_22637580 1.61 ENST00000402322.1
complement C1q A chain
chr2_-_68952880 1.61 ENST00000481498.1
ENST00000328895.9
gastrokine 2
chr2_+_142877653 1.60 ENST00000375773.6
ENST00000409512.5
ENST00000264170.9
ENST00000410015.6
kynureninase
chr2_-_87825952 1.60 ENST00000398146.4
RANBP2 like and GRIP domain containing 2
chr1_+_241848183 1.58 ENST00000366548.8
ENST00000423131.5
ENST00000523590.5
exonuclease 1
chr14_+_94581388 1.56 ENST00000554866.5
ENST00000556775.5
serpin family A member 5
chr11_-_60183011 1.56 ENST00000533023.5
ENST00000420732.6
ENST00000528851.6
membrane spanning 4-domains A6A
chr6_+_116461364 1.55 ENST00000368606.7
ENST00000368605.3
calcium homeostasis modulator family member 6
chr12_-_10884244 1.54 ENST00000543626.4
proline rich protein HaeIII subfamily 1
chr1_+_158931539 1.53 ENST00000368140.6
ENST00000368138.7
ENST00000392254.6
ENST00000392252.7
ENST00000368135.4
pyrin and HIN domain family member 1
chr6_+_22569554 1.51 ENST00000510882.4
HDGF like 1
chr14_+_100019375 1.50 ENST00000544450.6
Enah/Vasp-like
chr6_+_130421086 1.49 ENST00000545622.5
transmembrane protein 200A
chr22_+_22395005 1.49 ENST00000390298.2
immunoglobulin lambda variable 7-43
chr1_+_203765168 1.49 ENST00000367217.5
ENST00000442561.7
lymphocyte transmembrane adaptor 1
chr1_-_7853054 1.47 ENST00000361696.10
urotensin 2
chr19_-_49763295 1.47 ENST00000246801.8
testis specific serine kinase substrate
chr11_-_60183191 1.46 ENST00000412309.6
membrane spanning 4-domains A6A
chr11_-_104968533 1.44 ENST00000444739.7
caspase 4
chr4_+_99816797 1.41 ENST00000512369.2
ENST00000296414.11
dual adaptor of phosphotyrosine and 3-phosphoinositides 1
chr10_+_29289061 1.41 ENST00000375500.8
ENST00000649382.2
lysozyme like 1
chr11_-_74697694 1.41 ENST00000529912.5
chordin like 2
chr16_-_55833085 1.40 ENST00000360526.8
carboxylesterase 1
chr9_-_110337808 1.38 ENST00000374510.8
ENST00000374507.4
ENST00000423740.7
ENST00000374511.7
thioredoxin domain containing 8
chr3_+_132597260 1.37 ENST00000249887.3
atypical chemokine receptor 4
chr3_-_183555696 1.37 ENST00000341319.8
kelch like family member 6
chr2_+_88897230 1.37 ENST00000390244.2
immunoglobulin kappa variable 5-2
chrX_+_108044967 1.37 ENST00000415430.7
V-set and immunoglobulin domain containing 1
chr1_-_113871665 1.35 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
protein tyrosine phosphatase non-receptor type 22
chr5_+_119333151 1.33 ENST00000513374.1
TNF alpha induced protein 8
chr3_+_171843337 1.32 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
transmembrane protein 212
chr11_+_60280577 1.30 ENST00000679988.1
membrane spanning 4-domains A4A
chrX_+_12791353 1.30 ENST00000380663.7
ENST00000398491.6
ENST00000380668.10
ENST00000489404.5
phosphoribosyl pyrophosphate synthetase 2
chrX_+_83861126 1.26 ENST00000621735.4
ENST00000329312.5
cylicin 1
chr14_+_21736136 1.26 ENST00000390426.2
T cell receptor alpha variable 4
chr22_+_22644475 1.25 ENST00000618722.4
ENST00000652219.1
ENST00000480559.6
ENST00000448514.2
ENST00000652249.1
ENST00000651213.1
gamma-glutamyltransferase light chain 2
chr2_+_89985922 1.25 ENST00000390268.2
immunoglobulin kappa variable 2D-26
chr10_+_94938649 1.24 ENST00000461906.1
ENST00000260682.8
cytochrome P450 family 2 subfamily C member 9
chr8_-_107498041 1.23 ENST00000297450.7
angiopoietin 1
chrX_+_12906612 1.23 ENST00000218032.7
toll like receptor 8
chr4_+_89901979 1.23 ENST00000508372.1
multimerin 1
chr8_-_63026179 1.23 ENST00000677919.1
gamma-glutamyl hydrolase
chrX_+_78747705 1.22 ENST00000614823.5
ENST00000435339.3
ENST00000514744.5
lysophosphatidic acid receptor 4
chr14_-_106389858 1.21 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr14_-_106025628 1.21 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr5_+_169584029 1.20 ENST00000513795.1
spindle apparatus coiled-coil protein 1
chr10_-_14572123 1.20 ENST00000378465.7
ENST00000452706.6
ENST00000622567.4
ENST00000378458.6
family with sequence similarity 107 member B
chr12_-_90955172 1.20 ENST00000358859.3
coiled-coil glutamate rich protein 1
chr5_+_122160168 1.19 ENST00000509403.6
ENST00000514637.1
novel zinc finger protein
chr19_+_3762705 1.18 ENST00000589174.1
mitochondrial ribosomal protein L54
chr7_-_4862015 1.16 ENST00000404991.2
poly(A) polymerase beta
chr7_-_122699108 1.16 ENST00000340112.3
ring finger protein 133
chr6_+_106541111 1.14 ENST00000457437.1
crystallin beta-gamma domain containing 1
chr12_+_10929229 1.14 ENST00000381847.7
ENST00000396400.4
proline rich protein HaeIII subfamily 2
chr8_-_107497909 1.13 ENST00000517746.6
angiopoietin 1
chr7_-_116030735 1.11 ENST00000393485.5
transcription factor EC
chr8_-_85378105 1.11 ENST00000521846.5
ENST00000523022.6
ENST00000524324.5
ENST00000519991.5
ENST00000520663.5
ENST00000517590.5
ENST00000522579.5
ENST00000522814.5
ENST00000522662.5
ENST00000523858.5
ENST00000519129.5
carbonic anhydrase 1
chrX_-_42778155 1.11 ENST00000378131.4
PPP1R2C family member C
chrX_-_141585011 1.10 ENST00000370519.3
sperm protein associated with the nucleus, X-linked, family member A1
chr1_-_92486916 1.10 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr5_-_181243880 1.10 ENST00000511566.5
ENST00000511900.5
ENST00000504726.1
ENST00000512968.5
ENST00000626067.1
ENST00000376817.8
ENST00000513027.3
ENST00000512805.6
ENST00000503081.1
receptor for activated C kinase 1
chr7_+_142587857 1.10 ENST00000617639.1
T cell receptor beta variable 14
chrX_+_100644183 1.10 ENST00000640889.1
ENST00000373004.5
sushi repeat containing protein X-linked 2
chr3_-_27456743 1.10 ENST00000295736.9
ENST00000428386.5
ENST00000428179.1
solute carrier family 4 member 7
chr1_+_196943738 1.09 ENST00000367415.8
ENST00000367421.5
ENST00000649283.1
ENST00000476712.6
ENST00000496448.6
ENST00000473386.1
ENST00000649960.1
complement factor H related 2
chr15_+_69414304 1.09 ENST00000352331.8
ENST00000679126.1
ENST00000647715.1
ENST00000559279.6
kinesin family member 23
chr7_+_139829153 1.08 ENST00000652056.1
thromboxane A synthase 1
chr1_-_89022827 1.08 ENST00000370481.9
ENST00000564665.1
guanylate binding protein 3
chr11_+_114296347 1.08 ENST00000299964.4
nicotinamide N-methyltransferase
chr7_-_55516045 1.08 ENST00000453256.5
VOPP1 WW domain binding protein
chr2_+_201260510 1.07 ENST00000673742.1
caspase 8
chr2_+_113406368 1.07 ENST00000453673.3
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr12_-_11269696 1.07 ENST00000381842.7
proline rich protein BstNI subfamily 3
chr18_-_59318544 1.06 ENST00000587244.5
complexin 4
chr1_-_169734064 1.06 ENST00000333360.12
selectin E
chr10_+_46375619 1.05 ENST00000584982.7
ENST00000613703.4
annexin A8 like 1
chr6_+_27138588 1.04 ENST00000615353.1
H4 clustered histone 9
chr11_+_35189869 1.04 ENST00000525688.5
ENST00000278385.10
ENST00000533222.5
CD44 molecule (Indian blood group)
chr11_+_60280531 1.03 ENST00000532114.6
membrane spanning 4-domains A4A
chr14_+_88594430 1.03 ENST00000406216.7
ENST00000557737.1
zinc finger CCCH-type containing 14
chr1_-_169764648 1.03 ENST00000454271.1
ENST00000609271.1
novel transcript
selectin E
chr10_+_125973373 1.03 ENST00000417114.5
ENST00000445510.5
ENST00000368691.5
fibronectin type III and ankyrin repeat domains 1
chr20_-_13990609 1.01 ENST00000284951.10
ENST00000378072.5
SEL1L2 adaptor subunit of ERAD E3 ligase
chr11_+_35180279 1.01 ENST00000531873.5
CD44 molecule (Indian blood group)
chrX_+_108045050 1.01 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr1_-_99766620 1.01 ENST00000646001.2
ferric chelate reductase 1
chr2_+_168901290 1.00 ENST00000429379.2
ENST00000375363.8
ENST00000421979.1
glucose-6-phosphatase catalytic subunit 2
chr1_-_52404387 1.00 ENST00000371566.1
ENST00000371568.8
origin recognition complex subunit 1
chr3_-_49813880 0.99 ENST00000333486.4
ubiquitin like modifier activating enzyme 7
chr18_+_9885964 0.99 ENST00000357775.6
ENST00000306084.6
thioredoxin domain containing 2
chr16_+_1528674 0.99 ENST00000253934.9
transmembrane protein 204
chr2_-_89297785 0.98 ENST00000465170.1
immunoglobulin kappa variable 1-37 (non-functional)
chr3_-_149377637 0.98 ENST00000305366.8
transmembrane 4 L six family member 1
chr1_-_38881587 0.98 ENST00000357771.5
ENST00000621281.1
gap junction protein alpha 9
novel protein

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.8 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.9 2.7 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.8 2.4 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.7 2.2 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.6 8.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.6 1.7 GO:0060279 positive regulation of ovulation(GO:0060279)
0.5 2.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 3.2 GO:0061107 seminal vesicle development(GO:0061107)
0.5 1.6 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.5 1.5 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.5 82.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.5 1.9 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.4 4.2 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.4 4.3 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.4 2.0 GO:0039507 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.4 6.6 GO:0045059 positive thymic T cell selection(GO:0045059)
0.4 1.9 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.4 1.1 GO:0070105 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.4 3.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.3 5.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.3 0.3 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.3 1.0 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.3 4.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.3 3.4 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.3 8.0 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.3 1.8 GO:0072144 glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.3 0.9 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.3 1.8 GO:2000501 regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.3 5.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.3 1.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.3 0.8 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.3 0.8 GO:0016488 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.3 6.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.3 1.3 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.3 1.0 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.3 0.8 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 2.0 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 1.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 0.7 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.2 0.2 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2 0.7 GO:0036292 DNA rewinding(GO:0036292)
0.2 2.4 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2 1.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.2 8.9 GO:0045730 respiratory burst(GO:0045730)
0.2 0.6 GO:0021503 neural fold bending(GO:0021503)
0.2 1.4 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.2 1.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.6 GO:0060003 copper ion export(GO:0060003)
0.2 1.5 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.2 2.4 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.2 0.7 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 2.5 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 1.6 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.2 0.5 GO:0016999 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.2 1.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.2 0.9 GO:0032571 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.2 0.5 GO:0006463 steroid hormone receptor complex assembly(GO:0006463)
0.2 0.3 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.2 4.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.2 5.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 3.2 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.2 2.1 GO:0001787 natural killer cell proliferation(GO:0001787)
0.2 0.6 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 0.4 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808) negative regulation of hypersensitivity(GO:0002884)
0.1 0.3 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 1.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 3.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.1 0.6 GO:0072560 type B pancreatic cell maturation(GO:0072560)
0.1 2.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.4 GO:0008057 eye pigment granule organization(GO:0008057)
0.1 0.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.4 GO:1903123 regulation of thioredoxin peroxidase activity(GO:1903123) negative regulation of thioredoxin peroxidase activity(GO:1903124) negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation(GO:1903125) Wnt signalosome assembly(GO:1904887) negative regulation of peroxidase activity(GO:2000469)
0.1 0.5 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.6 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.7 GO:0070269 pyroptosis(GO:0070269)
0.1 0.3 GO:1903414 spleen trabecula formation(GO:0060345) divalent metal ion export(GO:0070839) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.1 2.5 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 2.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.3 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 2.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 0.7 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.5 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.6 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.1 1.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.5 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 2.7 GO:0042832 defense response to protozoan(GO:0042832)
0.1 0.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.3 GO:1901291 negative regulation of double-strand break repair via single-strand annealing(GO:1901291)
0.1 0.3 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.1 0.4 GO:0033037 polysaccharide localization(GO:0033037)
0.1 2.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.3 GO:0100057 regulation of phenotypic switching by transcription from RNA polymerase II promoter(GO:0100057) regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.1 0.6 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.1 1.7 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.3 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.5 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 2.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.7 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 15.5 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 6.2 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.1 1.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.4 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.4 GO:0072011 glomerular endothelium development(GO:0072011)
0.1 0.5 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 1.3 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.9 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 1.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 1.4 GO:0002467 germinal center formation(GO:0002467)
0.1 0.3 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.1 0.4 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.6 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.4 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.9 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.4 GO:0009804 coumarin metabolic process(GO:0009804)
0.1 0.7 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 1.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 1.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 0.2 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.1 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.5 GO:0001912 positive regulation of leukocyte mediated cytotoxicity(GO:0001912)
0.0 0.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.9 GO:0097242 beta-amyloid clearance(GO:0097242)
0.0 0.9 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 1.5 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 1.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.2 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.6 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.6 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.6 GO:0008228 opsonization(GO:0008228)
0.0 0.2 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.5 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.5 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0035698 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.0 0.6 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 2.1 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.7 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.6 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 1.7 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 2.4 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.4 GO:0071287 cellular response to manganese ion(GO:0071287)
0.0 2.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.2 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 2.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.9 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.9 GO:0035855 megakaryocyte development(GO:0035855)
0.0 4.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.9 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 1.0 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 1.3 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.6 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 1.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.9 GO:1902400 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0 1.0 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.3 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0033168 conversion of ds siRNA to ss siRNA involved in RNA interference(GO:0033168) conversion of ds siRNA to ss siRNA(GO:0036404)
0.0 0.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.6 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.2 GO:2000795 lung ciliated cell differentiation(GO:0061141) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 2.6 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.6 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.6 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.4 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.4 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.5 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.0 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.4 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.3 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.9 GO:0045143 homologous chromosome segregation(GO:0045143)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0033150 cytoskeletal calyx(GO:0033150)
0.8 3.2 GO:0097183 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.7 2.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.6 35.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.6 1.7 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.5 6.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.4 0.8 GO:0043159 acrosomal matrix(GO:0043159)
0.4 1.6 GO:0005602 complement component C1 complex(GO:0005602)
0.4 2.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.3 0.8 GO:1990716 axonemal central apparatus(GO:1990716)
0.3 1.9 GO:0097149 centralspindlin complex(GO:0097149)
0.3 1.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 10.1 GO:0001891 phagocytic cup(GO:0001891)
0.2 1.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 1.4 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.2 3.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 2.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 1.9 GO:0032010 phagolysosome(GO:0032010)
0.2 2.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 3.8 GO:0042101 T cell receptor complex(GO:0042101)
0.2 0.6 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.6 GO:0097229 sperm end piece(GO:0097229)
0.1 1.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.4 GO:0032473 cytoplasmic side of mitochondrial outer membrane(GO:0032473) caveola neck(GO:0099400)
0.1 2.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.6 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.9 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 6.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.8 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.3 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 0.6 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 1.0 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.5 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 2.9 GO:0036019 endolysosome(GO:0036019)
0.1 1.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.9 GO:0097342 ripoptosome(GO:0097342)
0.1 0.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.3 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 2.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.0 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.1 GO:0045180 basal cortex(GO:0045180)
0.1 0.6 GO:0005610 laminin-5 complex(GO:0005610)
0.1 1.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.6 GO:0036128 CatSper complex(GO:0036128)
0.1 10.5 GO:0072562 blood microparticle(GO:0072562)
0.1 1.0 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0030849 X chromosome(GO:0000805) autosome(GO:0030849)
0.0 0.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 1.0 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 3.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 3.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0045179 apical cortex(GO:0045179)
0.0 2.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.4 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.6 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.4 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 4.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 1.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 4.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 2.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0033167 ARC complex(GO:0033167)
0.0 2.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 28.0 GO:0005615 extracellular space(GO:0005615)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 6.9 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 3.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.4 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.6 GO:0005669 transcription factor TFIID complex(GO:0005669)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.9 2.7 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.8 3.8 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.7 2.2 GO:0008859 exoribonuclease II activity(GO:0008859)
0.7 3.4 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.6 1.7 GO:0017129 triglyceride binding(GO:0017129)
0.5 35.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.4 3.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.4 1.6 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.4 2.7 GO:0030492 hemoglobin binding(GO:0030492)
0.4 1.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.3 1.0 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3 4.2 GO:0032027 myosin light chain binding(GO:0032027)
0.3 1.6 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.3 3.2 GO:0032190 acrosin binding(GO:0032190)
0.3 2.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.3 5.6 GO:0003796 lysozyme activity(GO:0003796)
0.3 2.2 GO:0043515 kinetochore binding(GO:0043515)
0.3 0.6 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.3 2.0 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.3 3.0 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.3 2.4 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.3 0.8 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.2 51.9 GO:0003823 antigen binding(GO:0003823)
0.2 1.4 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.2 0.8 GO:0004040 amidase activity(GO:0004040)
0.2 1.0 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 2.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 1.7 GO:0034711 inhibin binding(GO:0034711)
0.2 2.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 1.8 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 0.5 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.2 2.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 1.0 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 0.6 GO:0033265 choline binding(GO:0033265)
0.2 1.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 1.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 1.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 0.8 GO:0048030 disaccharide binding(GO:0048030)
0.2 1.5 GO:0004064 arylesterase activity(GO:0004064)
0.1 2.1 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 1.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.4 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.4 GO:0034211 GTP-dependent protein kinase activity(GO:0034211) peroxidase inhibitor activity(GO:0036479)
0.1 0.3 GO:0097689 iron channel activity(GO:0097689)
0.1 0.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 1.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.8 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 4.0 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.3 GO:0034039 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity(GO:0034039)
0.1 0.3 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 0.3 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.1 0.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 2.5 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.3 GO:0072545 tyrosine binding(GO:0072545)
0.1 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 3.2 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.7 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 6.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.4 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.6 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.7 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.7 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 0.6 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 1.0 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.5 GO:0005522 profilin binding(GO:0005522)
0.1 0.8 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 0.2 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 2.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.2 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.1 5.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.4 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.4 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 1.5 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.3 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.8 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.8 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 10.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.8 GO:0001848 complement binding(GO:0001848)
0.0 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 1.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 1.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.4 GO:0019825 oxygen binding(GO:0019825)
0.0 2.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 3.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 7.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 4.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 1.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 2.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 3.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.0 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.4 PID IL23 PATHWAY IL23-mediated signaling events
0.1 7.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 4.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 4.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 3.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.5 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 5.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 8.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.0 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.8 PID AURORA B PATHWAY Aurora B signaling
0.0 1.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 8.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 1.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 3.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.0 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.3 6.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 4.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 2.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 1.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 3.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 3.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 2.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 2.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 2.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.9 REACTOME KINESINS Genes involved in Kinesins
0.0 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 4.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 2.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.7 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 1.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 2.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME TRIF MEDIATED TLR3 SIGNALING Genes involved in TRIF mediated TLR3 signaling
0.0 2.2 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.7 REACTOME SIGNALING BY ILS Genes involved in Signaling by Interleukins
0.0 1.3 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation