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Illumina Body Map 2 (GSE30611)

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Results for ISL2

Z-value: 0.80

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Transcription factors associated with ISL2

Gene Symbol Gene ID Gene Info
ENSG00000159556.10 ISL LIM homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ISL2hg38_v1_chr15_+_76336755_763367790.154.1e-01Click!

Activity profile of ISL2 motif

Sorted Z-values of ISL2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_55182442 1.91 ENST00000545075.3
MT-RNR2 like 10
chr5_+_40909490 1.76 ENST00000313164.10
complement C7
chr1_-_237945275 1.69 ENST00000604646.1
MT-RNR2 like 11
chr11_-_13495984 1.64 ENST00000282091.6
parathyroid hormone
chr10_-_29634964 1.64 ENST00000375398.6
ENST00000355867.8
supervillin
chr11_-_13496018 1.34 ENST00000529816.1
parathyroid hormone
chrX_-_85379659 1.32 ENST00000262753.9
POF1B actin binding protein
chr2_+_233760265 1.31 ENST00000305208.10
ENST00000360418.4
UDP glucuronosyltransferase family 1 member A1
chr2_-_189582012 1.31 ENST00000427419.5
ENST00000455320.5
solute carrier family 40 member 1
chr17_-_66229380 1.25 ENST00000205948.11
apolipoprotein H
chr1_+_62597510 1.22 ENST00000371129.4
angiopoietin like 3
chr21_+_38272410 1.20 ENST00000398934.5
ENST00000398930.5
potassium inwardly rectifying channel subfamily J member 15
chr1_-_178871022 1.13 ENST00000367629.1
angiopoietin like 1
chr1_-_178871060 1.12 ENST00000234816.7
angiopoietin like 1
chr8_+_91249307 1.11 ENST00000309536.6
ENST00000276609.8
solute carrier family 26 member 7
chr4_+_112647059 1.06 ENST00000511529.1
La ribonucleoprotein 7, transcriptional regulator
chr2_+_233671879 1.05 ENST00000354728.5
UDP glucuronosyltransferase family 1 member A9
chr7_+_123601815 1.05 ENST00000451215.6
ankyrin repeat and SOCS box containing 15
chr2_-_162152239 1.05 ENST00000418842.7
glucagon
chr2_+_167135901 1.05 ENST00000628543.2
xin actin binding repeat containing 2
chr8_+_132897674 1.03 ENST00000518505.1
thyroglobulin
chr7_+_123601836 1.03 ENST00000434204.5
ankyrin repeat and SOCS box containing 15
chr2_-_162152404 1.01 ENST00000375497.3
glucagon
chr7_-_120857124 0.97 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr15_+_58410543 0.95 ENST00000356113.10
ENST00000414170.7
lipase C, hepatic type
chr14_-_67412112 0.94 ENST00000216446.9
pleckstrin 2
chr10_-_93482326 0.92 ENST00000359263.9
myoferlin
chr7_+_123601859 0.87 ENST00000437535.5
ankyrin repeat and SOCS box containing 15
chr10_-_93482194 0.84 ENST00000358334.9
ENST00000371488.3
myoferlin
chr19_+_14583076 0.83 ENST00000547437.5
ENST00000417570.6
C-type lectin domain containing 17A
chrX_-_85379703 0.82 ENST00000373145.3
POF1B actin binding protein
chr4_+_94207596 0.82 ENST00000359052.8
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr7_-_16804987 0.81 ENST00000401412.5
ENST00000419304.7
anterior gradient 2, protein disulphide isomerase family member
chr10_-_93482287 0.80 ENST00000371489.5
myoferlin
chr5_+_132873660 0.80 ENST00000296877.3
liver enriched antimicrobial peptide 2
chr15_+_90191913 0.79 ENST00000559792.5
semaphorin 4B
chr20_+_31514410 0.78 ENST00000335574.10
ENST00000340852.9
ENST00000398174.9
ENST00000466766.2
ENST00000498035.5
ENST00000344042.5
histocompatibility minor 13
chrX_-_21658324 0.71 ENST00000379499.3
kelch like family member 34
chr2_+_233917371 0.70 ENST00000324695.9
ENST00000433712.6
transient receptor potential cation channel subfamily M member 8
chr6_+_130018565 0.68 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr2_-_10447771 0.68 ENST00000405333.5
ENST00000443218.1
ornithine decarboxylase 1
chr15_+_64387828 0.66 ENST00000261884.8
thyroid hormone receptor interactor 4
chr5_+_40841308 0.63 ENST00000381677.4
ENST00000254691.10
caspase recruitment domain family member 6
chr12_+_130953898 0.61 ENST00000261654.10
adhesion G protein-coupled receptor D1
chr4_-_174263080 0.60 ENST00000615392.4
F-box protein 8
chr16_+_28553908 0.59 ENST00000317058.8
SAGA complex associated factor 29
chr3_-_122022122 0.59 ENST00000393631.5
ENST00000273691.7
ENST00000344209.10
immunoglobulin like domain containing receptor 1
chrX_-_31266857 0.58 ENST00000378702.8
ENST00000361471.8
dystrophin
chr11_-_8871385 0.56 ENST00000527516.5
ENST00000533471.5
DENN domain containing 2B
chr4_+_85604146 0.56 ENST00000512201.5
Rho GTPase activating protein 24
chr3_+_136930469 0.56 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr2_+_87748087 0.56 ENST00000359481.9
plasminogen like B2
chr2_-_157439403 0.55 ENST00000418920.5
cytohesin 1 interacting protein
chrX_-_15314543 0.55 ENST00000344384.8
ankyrin repeat and SOCS box containing 11
chrX_-_31266925 0.54 ENST00000680557.1
ENST00000378680.6
ENST00000378723.7
ENST00000680768.2
ENST00000681870.1
ENST00000680355.1
ENST00000682322.1
ENST00000682600.1
ENST00000680162.2
ENST00000681153.1
ENST00000681334.1
dystrophin
chr14_+_21997531 0.54 ENST00000390445.2
T cell receptor alpha variable 17
chr7_-_120858066 0.51 ENST00000222747.8
tetraspanin 12
chr13_+_48976597 0.51 ENST00000541916.5
fibronectin type III domain containing 3A
chr20_-_35147285 0.50 ENST00000374491.3
ENST00000374492.8
ER degradation enhancing alpha-mannosidase like protein 2
chr2_+_86441995 0.49 ENST00000427678.1
lysine demethylase 3A
chrX_-_32155462 0.49 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chr21_-_30492008 0.46 ENST00000334063.6
keratin associated protein 19-3
chr4_-_48114523 0.46 ENST00000506073.1
TXK tyrosine kinase
chr3_-_142029108 0.45 ENST00000497579.5
transcription factor Dp-2
chr11_-_28108109 0.45 ENST00000263181.7
kinesin family member 18A
chr4_+_168497044 0.44 ENST00000505667.6
palladin, cytoskeletal associated protein
chr7_+_16661182 0.44 ENST00000446596.5
ENST00000452975.6
ENST00000438834.5
basic leucine zipper and W2 domains 2
chr19_-_45730861 0.44 ENST00000317683.4
F-box protein 46
chr6_+_54099538 0.43 ENST00000447836.6
muscular LMNA interacting protein
chr7_-_116030750 0.43 ENST00000265440.12
ENST00000320239.11
transcription factor EC
chr2_-_40453438 0.42 ENST00000455476.5
solute carrier family 8 member A1
chr19_+_3185911 0.42 ENST00000246117.9
ENST00000588428.5
nicalin
chr14_+_22202561 0.42 ENST00000390460.1
T cell receptor alpha variable 26-2
chr7_-_116030735 0.42 ENST00000393485.5
transcription factor EC
chr12_-_56741535 0.42 ENST00000647707.1
novel protein
chr1_-_225428813 0.41 ENST00000338179.6
ENST00000425080.1
lamin B receptor
chr12_-_57818704 0.41 ENST00000549994.1
advillin
chr2_-_169031317 0.41 ENST00000650372.1
ATP binding cassette subfamily B member 11
chr4_+_168497066 0.41 ENST00000261509.10
palladin, cytoskeletal associated protein
chr17_-_49709014 0.40 ENST00000511657.1
solute carrier family 35 member B1
chr11_+_28108248 0.40 ENST00000406787.7
ENST00000403099.5
ENST00000407364.8
methyltransferase like 15
chr3_+_186974957 0.40 ENST00000438590.5
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr4_-_67963441 0.39 ENST00000508048.6
transmembrane serine protease 11A
chr12_+_64405046 0.37 ENST00000540203.5
exportin for tRNA
chr6_+_31137646 0.37 ENST00000547221.1
psoriasis susceptibility 1 candidate 1
chr19_+_49513353 0.36 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr4_+_25160631 0.36 ENST00000510415.1
ENST00000507794.2
ENST00000512921.4
SEPSECS antisense RNA 1 (head to head)
phosphatidylinositol 4-kinase type 2 beta
chrX_+_83861126 0.36 ENST00000621735.4
ENST00000329312.5
cylicin 1
chr8_-_123729211 0.36 ENST00000520519.1
annexin A13
chr4_+_94207845 0.36 ENST00000457823.6
ENST00000354268.9
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr20_-_52105644 0.35 ENST00000371523.8
ZFP64 zinc finger protein
chr7_-_45111673 0.34 ENST00000461363.1
ENST00000258770.8
ENST00000495078.1
ENST00000494076.5
ENST00000478532.5
ENST00000361278.7
transforming growth factor beta regulator 4
chr19_+_48695952 0.34 ENST00000522966.2
ENST00000425340.3
ENST00000391876.5
fucosyltransferase 2
chr9_+_72577369 0.33 ENST00000651183.1
transmembrane channel like 1
chr8_+_69492793 0.33 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
sulfatase 1
chr5_+_102865244 0.33 ENST00000511477.5
ENST00000506006.1
ENST00000509832.5
peptidylglycine alpha-amidating monooxygenase
chr20_+_45420585 0.32 ENST00000639239.1
phosphatidylinositol glycan anchor biosynthesis class T
chr2_-_87021844 0.32 ENST00000355705.4
ENST00000409310.6
plasminogen like B1
chr6_+_54099565 0.31 ENST00000511678.5
muscular LMNA interacting protein
chr12_-_110499546 0.30 ENST00000552130.6
VPS29 retromer complex component
chr10_-_114144599 0.30 ENST00000428953.1
coiled-coil domain containing 186
chr6_+_63635792 0.29 ENST00000262043.8
ENST00000506783.5
ENST00000481385.6
ENST00000515594.5
ENST00000494284.6
PHD finger protein 3
chr11_-_26723361 0.29 ENST00000533617.5
solute carrier family 5 member 12
chr16_+_86566821 0.29 ENST00000649859.1
forkhead box C2
chr2_-_84881238 0.29 ENST00000335459.9
TraB domain containing 2A
chr14_+_34993240 0.29 ENST00000677647.1
signal recognition particle 54
chr5_+_58491451 0.28 ENST00000513924.2
ENST00000515443.2
GRB2 binding adaptor protein, transmembrane
chr12_+_4720395 0.28 ENST00000252318.7
polypeptide N-acetylgalactosaminyltransferase 8
chr4_-_103019634 0.28 ENST00000510559.1
ENST00000296422.12
ENST00000394789.7
solute carrier family 9 member B1
chr6_-_49964160 0.28 ENST00000322066.4
defensin beta 114
chr5_+_58491427 0.28 ENST00000396776.6
ENST00000502276.6
ENST00000511930.2
GRB2 binding adaptor protein, transmembrane
chr1_-_17439657 0.27 ENST00000375436.9
regulator of chromosome condensation 2
chr7_-_33100886 0.27 ENST00000448915.1
RP9 pre-mRNA splicing factor
chr13_-_46142834 0.27 ENST00000674665.1
lymphocyte cytosolic protein 1
chr1_-_169703329 0.27 ENST00000497295.1
selectin L
chr22_-_28711931 0.27 ENST00000434810.5
ENST00000456369.5
checkpoint kinase 2
chrM_+_9207 0.26 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr6_-_111483700 0.26 ENST00000435970.5
ENST00000358835.7
REV3 like, DNA directed polymerase zeta catalytic subunit
chr4_-_137532452 0.26 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr12_-_95551417 0.26 ENST00000258499.8
ubiquitin specific peptidase 44
chr14_+_60982358 0.26 ENST00000526105.5
solute carrier family 38 member 6
chr17_-_10469558 0.25 ENST00000255381.2
myosin heavy chain 4
chr2_+_127419686 0.25 ENST00000427769.5
protein C, inactivator of coagulation factors Va and VIIIa
chr1_-_247760556 0.25 ENST00000641256.1
olfactory receptor family 1 subfamily C member 1
chr15_+_78077798 0.25 ENST00000409568.6
SH2 domain containing 7
chr7_-_42152396 0.24 ENST00000642432.1
ENST00000647255.1
ENST00000677288.1
GLI family zinc finger 3
chr6_-_155455830 0.24 ENST00000159060.3
NADPH oxidase 3
chr3_-_150703965 0.23 ENST00000498386.1
glutamate rich 6
chr4_+_155854758 0.22 ENST00000506072.5
ENST00000507590.5
tryptophan 2,3-dioxygenase
chr17_+_10697576 0.22 ENST00000379774.5
ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
chr17_-_7404039 0.21 ENST00000576017.1
ENST00000302422.4
transmembrane protein 256
chr3_-_186544377 0.21 ENST00000307944.6
crystallin gamma S
chr11_+_55723776 0.21 ENST00000641440.1
olfactory receptor family 5 subfamily D member 3 pseudogene
chr17_-_40999903 0.20 ENST00000391587.3
keratin associated protein 3-2
chr11_+_5389377 0.20 ENST00000328611.5
olfactory receptor family 51 subfamily M member 1
chr12_-_118190510 0.20 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr14_+_22096017 0.20 ENST00000390452.2
T cell receptor delta variable 1
chrM_+_10055 0.19 ENST00000361227.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3
chr7_-_111392915 0.19 ENST00000450877.5
inner mitochondrial membrane peptidase subunit 2
chr17_+_7252502 0.19 ENST00000570322.5
ENST00000576496.5
ENST00000574841.2
elongator acetyltransferase complex subunit 5
chrY_-_23694579 0.19 ENST00000343584.10
PTPN13 like Y-linked pseudogene 3
chr17_+_1771688 0.18 ENST00000572048.1
ENST00000573763.1
serpin family F member 1
chr2_-_206213430 0.18 ENST00000447845.1
G protein-coupled receptor 1
chr1_-_152806628 0.18 ENST00000606576.1
ENST00000607093.2
late cornified envelope 1C
chr17_-_8210203 0.18 ENST00000578549.5
ENST00000582368.5
aurora kinase B
chr9_+_108862255 0.18 ENST00000333999.5
actin like 7A
chr2_+_108239965 0.18 ENST00000681802.2
ENST00000329106.3
sulfotransferase family 1C member 3
chr3_-_191282383 0.17 ENST00000427544.6
urotensin 2B
chr4_-_119322128 0.17 ENST00000274024.4
fatty acid binding protein 2
chr17_-_64390592 0.17 ENST00000563523.5
platelet and endothelial cell adhesion molecule 1
chr20_-_31390483 0.16 ENST00000376315.2
defensin beta 119
chrY_+_18546691 0.16 ENST00000309834.8
ENST00000307393.3
ENST00000382856.2
heat shock transcription factor Y-linked 1
chr4_+_168497113 0.16 ENST00000511948.1
palladin, cytoskeletal associated protein
chr19_-_44529687 0.16 ENST00000621342.4
ENST00000617951.1
CEA cell adhesion molecule 20
chr11_-_5548540 0.15 ENST00000322653.7
olfactory receptor family 52 subfamily H member 1
chr13_+_30422487 0.15 ENST00000638137.1
ENST00000635918.2
ubiquitin conjugating enzyme E2 L5
chr10_+_94762673 0.15 ENST00000480405.2
ENST00000371321.9
cytochrome P450 family 2 subfamily C member 19
chr14_+_21621801 0.15 ENST00000542354.1
T cell receptor alpha variable 1-1
chr4_+_70242583 0.15 ENST00000304954.3
casein kappa
chr15_-_75455767 0.15 ENST00000360439.8
SIN3 transcription regulator family member A
chr3_+_169911566 0.14 ENST00000428432.6
ENST00000335556.7
sterile alpha motif domain containing 7
chr7_-_84492718 0.14 ENST00000424555.5
semaphorin 3A
chr16_+_53099100 0.14 ENST00000565832.5
chromodomain helicase DNA binding protein 9
chr16_-_1488764 0.13 ENST00000447419.7
ENST00000440447.2
pentraxin 4
chr5_-_131165231 0.13 ENST00000675100.1
ENST00000304043.10
ENST00000513012.2
histidine triad nucleotide binding protein 1
chr11_-_124320197 0.13 ENST00000624618.2
olfactory receptor family 8 subfamily D member 2
chr17_+_7428831 0.12 ENST00000636696.4
ENST00000651079.1
SPEM family member 3
chr14_+_19719015 0.12 ENST00000557414.1
olfactory receptor family 4 subfamily N member 2
chr14_-_55440616 0.12 ENST00000247219.5
TATA-box binding protein like 2
chr6_-_138512493 0.12 ENST00000533765.1
NHS like 1
chr11_+_35186820 0.11 ENST00000531110.6
ENST00000525685.6
CD44 molecule (Indian blood group)
chr11_-_16397521 0.10 ENST00000533411.5
SRY-box transcription factor 6
chr3_+_40477107 0.10 ENST00000314686.9
ENST00000447116.6
ENST00000429348.6
ENST00000432264.4
ENST00000456778.5
zinc finger protein 619
chr12_+_55444069 0.10 ENST00000641516.1
ENST00000641202.1
olfactory receptor family 6 subfamily C member 2
chr1_+_98661666 0.09 ENST00000529992.5
sorting nexin 7
chr12_+_1970772 0.09 ENST00000682544.1
calcium voltage-gated channel subunit alpha1 C
chr12_+_69825273 0.09 ENST00000547771.6
myelin regulatory factor like
chr17_-_7315312 0.08 ENST00000577040.2
ENST00000389167.9
ENST00000380728.7
G protein pathway suppressor 2
chr1_+_112718880 0.08 ENST00000361886.4
TAFA chemokine like family member 3
chrX_-_101617921 0.08 ENST00000361910.9
ENST00000538627.5
ENST00000539247.5
armadillo repeat containing X-linked 6
chr1_+_13303539 0.08 ENST00000437300.2
PRAME family member 33
chr1_+_149899561 0.08 ENST00000369152.6
bolA family member 1
chr10_-_5003850 0.08 ENST00000421196.7
ENST00000455190.2
ENST00000380753.8
aldo-keto reductase family 1 member C2
chrX_-_72808210 0.07 ENST00000419795.6
ENST00000458170.1
family with sequence similarity 236 member D
chr2_-_206213362 0.07 ENST00000442134.1
G protein-coupled receptor 1
chr15_+_48191648 0.07 ENST00000646012.1
ENST00000561127.5
ENST00000647546.1
ENST00000559641.5
ENST00000417307.3
solute carrier family 12 member 1
cortexin 2
chr5_+_111092172 0.07 ENST00000612402.4
WD repeat domain 36
chr13_+_23570370 0.07 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr11_-_56614874 0.07 ENST00000641076.1
olfactory receptor family 5 subfamily M member 1
chr2_-_158380960 0.07 ENST00000409187.5
coiled-coil domain containing 148
chr1_-_13056575 0.06 ENST00000436041.6
PRAME family member 27
chr11_-_62754141 0.06 ENST00000527994.1
ENST00000394807.5
ENST00000673933.1
zinc finger and BTB domain containing 3
chr11_-_75089754 0.06 ENST00000305159.3
olfactory receptor family 2 subfamily AT member 4
chr12_+_55492378 0.06 ENST00000548615.1
olfactory receptor family 6 subfamily C member 68
chr11_-_63608542 0.06 ENST00000540943.1
phospholipase A and acyltransferase 3
chr1_+_149899618 0.06 ENST00000369150.1
bolA family member 1
chr12_-_54295748 0.06 ENST00000540264.2
ENST00000312156.8
nuclear factor, erythroid 2
chr1_-_223665723 0.06 ENST00000366873.6
calpain 8
chr12_+_1970809 0.06 ENST00000683781.1
ENST00000682462.1
calcium voltage-gated channel subunit alpha1 C
chr6_-_24358036 0.05 ENST00000378454.8
doublecortin domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ISL2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.4 1.3 GO:1903988 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.3 2.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3 1.3 GO:0018879 biphenyl metabolic process(GO:0018879)
0.3 0.8 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 0.6 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.2 0.5 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.2 0.8 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.1 2.6 GO:0001778 plasma membrane repair(GO:0001778)
0.1 1.1 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.5 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.4 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.7 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 1.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 1.2 GO:0051005 negative regulation of phospholipase activity(GO:0010519) negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.4 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 1.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.6 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.7 GO:0050955 thermoception(GO:0050955)
0.1 0.3 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.6 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 1.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.0 GO:0015705 iodide transport(GO:0015705)
0.1 0.9 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.5 GO:0072011 glomerular endothelium development(GO:0072011)
0.1 0.3 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.1 0.3 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 1.1 GO:0019532 oxalate transport(GO:0019532)
0.1 0.4 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.5 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.2 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.2 GO:0060875 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.1 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.3 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.3 GO:0018032 protein amidation(GO:0018032)
0.0 0.3 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 1.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 1.0 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.4 GO:0071313 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.0 0.6 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.2 GO:0048840 otolith development(GO:0048840)
0.0 1.5 GO:0010842 retina layer formation(GO:0010842)
0.0 1.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 2.1 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.3 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.3 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.3 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.7 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.8 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.4 GO:0033150 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.1 1.6 GO:0016013 syntrophin complex(GO:0016013)
0.1 1.6 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 1.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.6 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.9 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.2 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.3 GO:0002102 podosome(GO:0002102)
0.0 2.6 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.0 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.4 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 1.1 GO:0055038 recycling endosome membrane(GO:0055038)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0097689 iron channel activity(GO:0097689)
0.2 1.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 0.6 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.4 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.4 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.1 0.8 GO:0042806 fucose binding(GO:0042806)
0.1 0.8 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.4 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 3.0 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.4 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 2.4 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 2.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.3 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 3.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.3 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 4.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.8 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 2.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 1.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 3.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins