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Illumina Body Map 2 (GSE30611)

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Results for ISX

Z-value: 0.69

Motif logo

Transcription factors associated with ISX

Gene Symbol Gene ID Gene Info
ENSG00000175329.13 intestine specific homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ISXhg38_v1_chr22_+_35066136_350661630.163.7e-01Click!

Activity profile of ISX motif

Sorted Z-values of ISX motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_16347637 2.78 ENST00000543076.5
ENST00000396210.8
microsomal glutathione S-transferase 1
chr12_+_16347102 2.76 ENST00000536371.5
ENST00000010404.6
microsomal glutathione S-transferase 1
chr12_+_16347665 2.74 ENST00000535309.5
ENST00000540056.5
ENST00000396209.5
ENST00000540126.5
microsomal glutathione S-transferase 1
chr19_+_4153616 2.48 ENST00000078445.7
ENST00000595923.5
ENST00000602257.5
ENST00000602147.1
cAMP responsive element binding protein 3 like 3
chr14_-_94323324 2.43 ENST00000341584.4
serpin family A member 6
chr6_+_160121809 2.33 ENST00000366963.9
solute carrier family 22 member 1
chr8_-_81483226 2.09 ENST00000256104.5
fatty acid binding protein 4
chrX_+_139530730 2.00 ENST00000218099.7
coagulation factor IX
chr4_-_99321362 1.98 ENST00000625860.2
ENST00000305046.13
ENST00000506651.5
alcohol dehydrogenase 1B (class I), beta polypeptide
chr6_+_160121859 1.94 ENST00000324965.8
ENST00000457470.6
solute carrier family 22 member 1
chr14_-_94323389 1.84 ENST00000557225.1
serpin family A member 6
chr7_+_120988683 1.79 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr16_-_55833085 1.78 ENST00000360526.8
carboxylesterase 1
chr2_+_216659600 1.40 ENST00000456764.1
insulin like growth factor binding protein 2
chr15_+_58138368 1.35 ENST00000219919.9
ENST00000536493.1
aquaporin 9
chr15_+_58138169 1.24 ENST00000558772.5
aquaporin 9
chr10_+_47322450 1.23 ENST00000581492.3
growth differentiation factor 2
chr11_-_125111708 1.15 ENST00000531909.5
ENST00000529530.1
transmembrane protein 218
chr7_-_88795732 1.09 ENST00000297203.3
testis expressed 47
chr4_-_176269213 1.08 ENST00000296525.7
ankyrin repeat and SOCS box containing 5
chr10_+_133347347 1.05 ENST00000463201.2
ENST00000433452.6
proline rich acidic protein 1
chr3_-_165837412 1.02 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
butyrylcholinesterase
chr4_+_107989714 1.02 ENST00000505878.4
ENST00000603302.5
ENST00000638621.1
hydroxyacyl-CoA dehydrogenase
chr4_-_68670648 1.01 ENST00000338206.6
UDP glucuronosyltransferase family 2 member B15
chr12_-_21910853 0.97 ENST00000544039.5
ATP binding cassette subfamily C member 9
chr4_+_107989880 0.96 ENST00000309522.8
ENST00000403312.6
ENST00000638559.1
ENST00000682373.1
hydroxyacyl-CoA dehydrogenase
chr4_-_137532452 0.94 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr5_-_95961830 0.90 ENST00000513343.1
ENST00000237853.9
elongation factor for RNA polymerase II 2
chr9_+_127397184 0.89 ENST00000419917.5
ENST00000373352.5
ENST00000373360.7
solute carrier family 2 member 8
chr6_+_54083423 0.88 ENST00000460844.6
ENST00000370876.6
muscular LMNA interacting protein
chrX_+_43656289 0.87 ENST00000338702.4
monoamine oxidase A
chr4_+_48016764 0.86 ENST00000295461.10
NIPA like domain containing 1
chr4_-_48016631 0.84 ENST00000513178.2
ENST00000514170.7
cyclic nucleotide gated channel subunit alpha 1
chr1_+_162366896 0.82 ENST00000420220.1
novel protein
chr9_+_127397153 0.80 ENST00000451404.5
ENST00000373371.8
solute carrier family 2 member 8
chr17_-_7404039 0.79 ENST00000576017.1
ENST00000302422.4
transmembrane protein 256
chr9_+_133636355 0.77 ENST00000393056.8
dopamine beta-hydroxylase
chr9_+_127397129 0.74 ENST00000610552.4
solute carrier family 2 member 8
chr6_+_25726767 0.72 ENST00000274764.5
H2B clustered histone 1
chr14_+_51847116 0.69 ENST00000553560.5
G protein subunit gamma 2
chr2_+_9951653 0.69 ENST00000324907.14
grainyhead like transcription factor 1
chr10_+_97446194 0.68 ENST00000370846.8
ENST00000352634.8
ENST00000353979.7
ENST00000370842.6
ENST00000345745.9
zinc finger DHHC-type palmitoyltransferase 16
chr10_-_97687191 0.67 ENST00000370626.4
arginine vasopressin induced 1
chr3_-_151316795 0.66 ENST00000260843.5
G protein-coupled receptor 87
chr4_+_154781213 0.64 ENST00000514866.5
ENST00000281722.8
RNA binding motif protein 46
chr16_-_31094727 0.64 ENST00000300851.10
ENST00000394975.3
vitamin K epoxide reductase complex subunit 1
chr6_-_84764581 0.63 ENST00000369663.10
T-box transcription factor 18
chr16_-_31094890 0.62 ENST00000532364.1
ENST00000529564.1
ENST00000319788.11
ENST00000354895.4
novel protein, VKORC1 and PRSS53 readthrough
vitamin K epoxide reductase complex subunit 1
chr20_-_51802433 0.62 ENST00000395997.3
spalt like transcription factor 4
chr16_-_31094549 0.62 ENST00000394971.7
vitamin K epoxide reductase complex subunit 1
chr20_-_51802509 0.61 ENST00000371539.7
ENST00000217086.9
spalt like transcription factor 4
chr1_+_220879434 0.61 ENST00000366903.8
H2.0 like homeobox
chr1_-_16978276 0.61 ENST00000375534.7
microfibril associated protein 2
chr9_+_133636378 0.60 ENST00000263611.3
dopamine beta-hydroxylase
chr4_+_76435216 0.59 ENST00000296043.7
shroom family member 3
chr1_+_40247926 0.59 ENST00000372766.4
transmembrane and coiled-coil domains 2
chr11_+_95789965 0.59 ENST00000537677.5
centrosomal protein 57
chr2_+_62705644 0.57 ENST00000427809.5
ENST00000405482.5
ENST00000431489.6
EH domain binding protein 1
chr2_+_86720282 0.56 ENST00000283632.5
required for meiotic nuclear division 5 homolog A
chr11_-_125111579 0.56 ENST00000532156.5
ENST00000532407.5
ENST00000279968.8
ENST00000527766.5
ENST00000529583.5
ENST00000524373.5
ENST00000527271.5
ENST00000526175.5
ENST00000529609.5
ENST00000682305.1
ENST00000533273.1
transmembrane protein 218
chr9_+_34646654 0.56 ENST00000378842.8
galactose-1-phosphate uridylyltransferase
chr9_+_127397314 0.55 ENST00000419132.5
solute carrier family 2 member 8
chr6_-_25726553 0.54 ENST00000297012.5
H2A clustered histone 1
chr3_+_140678041 0.54 ENST00000286349.4
tripartite motif containing 42
chr3_-_105869035 0.54 ENST00000447441.6
ENST00000403724.5
ENST00000405772.5
Cbl proto-oncogene B
chr17_-_42676980 0.51 ENST00000587627.1
ENST00000591022.6
ENST00000293349.10
pleckstrin homology, MyTH4 and FERM domain containing H3
chr11_+_77821125 0.51 ENST00000526415.5
ENST00000393427.6
ENST00000527134.5
ENST00000304716.12
ENST00000630098.2
adipogenesis associated Mth938 domain containing
chr4_+_154781344 0.51 ENST00000510397.5
RNA binding motif protein 46
chr11_-_62646598 0.51 ENST00000648273.1
ENST00000356638.8
ENST00000346178.8
ENST00000534779.5
ENST00000525994.1
ENST00000540933.5
glucosidase II alpha subunit
chr3_+_186570663 0.50 ENST00000265028.8
DnaJ heat shock protein family (Hsp40) member B11
chr10_+_97446137 0.50 ENST00000370854.7
ENST00000393760.6
ENST00000414567.5
zinc finger DHHC-type palmitoyltransferase 16
chr20_+_33217325 0.49 ENST00000375452.3
ENST00000375454.8
BPI fold containing family A member 3
chr9_-_35815034 0.49 ENST00000259667.6
histidine triad nucleotide binding protein 2
chr8_-_39838201 0.49 ENST00000347580.8
ENST00000379853.6
ENST00000265708.9
ENST00000521880.5
ADAM metallopeptidase domain 2
chr2_+_62705866 0.48 ENST00000263991.9
EH domain binding protein 1
chr9_+_34646589 0.48 ENST00000450095.6
galactose-1-phosphate uridylyltransferase
chrX_-_6535118 0.48 ENST00000381089.7
ENST00000612369.4
ENST00000398729.1
variable charge X-linked 3A
chr2_+_86907953 0.47 ENST00000409776.6
RANBP2 like and GRIP domain containing 1
chr9_+_34646627 0.47 ENST00000556278.1
novel protein (GALT-IL11RA readthrough)
chrX_+_7843088 0.47 ENST00000341408.5
variable charge X-linked
chr5_+_174724549 0.46 ENST00000239243.7
ENST00000507785.2
msh homeobox 2
chr22_-_28094135 0.46 ENST00000442232.1
tetratricopeptide repeat domain 28
chr3_-_105868964 0.45 ENST00000394030.8
Cbl proto-oncogene B
chr14_-_52069228 0.45 ENST00000617139.4
nidogen 2
chr3_+_51817596 0.45 ENST00000456080.5
novel protein
chr10_+_102226293 0.45 ENST00000370005.4
ELOVL fatty acid elongase 3
chr14_-_52069039 0.44 ENST00000216286.10
nidogen 2
chr6_-_134950081 0.44 ENST00000367847.2
ENST00000265605.7
ENST00000367845.6
aldehyde dehydrogenase 8 family member A1
chr19_+_42306937 0.42 ENST00000595750.2
proline rich 19
chr19_+_12791470 0.41 ENST00000302754.6
JunB proto-oncogene, AP-1 transcription factor subunit
chr17_-_42185452 0.41 ENST00000293330.1
hypocretin neuropeptide precursor
chr12_+_56080155 0.41 ENST00000267101.8
erb-b2 receptor tyrosine kinase 3
chr12_-_10802627 0.40 ENST00000240687.2
taste 2 receptor member 7
chr11_+_77821187 0.40 ENST00000525409.5
adipogenesis associated Mth938 domain containing
chrX_+_37994252 0.40 ENST00000448797.2
H2A.L variant histone R, pseudogene
chr22_+_28742024 0.40 ENST00000216027.8
ENST00000398941.6
HscB mitochondrial iron-sulfur cluster cochaperone
chr13_+_30422487 0.40 ENST00000638137.1
ENST00000635918.2
ubiquitin conjugating enzyme E2 L5
chr12_+_52301833 0.40 ENST00000293525.5
keratin 86
chr19_+_4007714 0.39 ENST00000262971.3
protein inhibitor of activated STAT 4
chr19_-_55464741 0.39 ENST00000635964.2
chromosome 19 open reading frame 85
chr1_+_151762899 0.39 ENST00000635322.1
ENST00000321531.10
ornithine decarboxylase antizyme 3
chr9_-_134068012 0.38 ENST00000303407.12
bromodomain containing 3
chr11_+_92969651 0.38 ENST00000257068.3
ENST00000528076.1
melatonin receptor 1B
chrX_+_30243715 0.38 ENST00000378981.8
ENST00000397550.6
MAGE family member B1
chr7_-_122699108 0.37 ENST00000340112.3
ring finger protein 133
chr8_+_22275309 0.37 ENST00000356766.11
ENST00000521356.5
piwi like RNA-mediated gene silencing 2
chrX_+_8465426 0.37 ENST00000381029.4
variable charge X-linked 3B
chrX_-_139832235 0.37 ENST00000327569.7
ENST00000361648.6
ATPase phospholipid transporting 11C
chr11_+_95790459 0.36 ENST00000325486.9
ENST00000325542.10
ENST00000544522.5
ENST00000541365.5
centrosomal protein 57
chr22_+_35648438 0.35 ENST00000409652.5
apolipoprotein L6
chrX_+_136205982 0.35 ENST00000628568.1
four and a half LIM domains 1
chr15_+_21579912 0.35 ENST00000628444.1
long intergenic non-protein coding RNA 2203
chr22_+_23966880 0.34 ENST00000215770.6
D-dopachrome tautomerase like
chr6_+_130018565 0.34 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr3_-_48621760 0.33 ENST00000330862.4
transmembrane protein 89
chr16_+_89093842 0.33 ENST00000317447.9
ENST00000614302.5
ENST00000537290.5
ENST00000540697.5
ENST00000406948.7
ENST00000378345.8
ENST00000541755.2
acyl-CoA synthetase family member 3
chr12_-_50396601 0.33 ENST00000327337.6
ENST00000543111.5
family with sequence similarity 186 member A
chr7_+_142111739 0.32 ENST00000550469.6
ENST00000477922.3
maltase-glucoamylase 2 (putative)
chr19_+_49513353 0.32 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr7_+_130381092 0.32 ENST00000484324.1
carboxypeptidase A1
chr8_-_61651086 0.32 ENST00000524173.5
aspartate beta-hydroxylase
chr9_-_4666495 0.32 ENST00000475086.5
spermatogenesis associated 6 like
chr19_+_12891151 0.32 ENST00000589039.5
ENST00000591470.5
ENST00000222214.10
ENST00000588905.5
ENST00000587072.1
glutaryl-CoA dehydrogenase
chr6_-_31862809 0.32 ENST00000375631.5
neuraminidase 1
chrX_+_44844015 0.31 ENST00000339042.6
dual specificity phosphatase 21
chrX_-_8171267 0.30 ENST00000317103.5
variable charge X-linked 2
chr6_+_36196710 0.30 ENST00000357641.10
bromodomain and PHD finger containing 3
chr12_+_104286881 0.30 ENST00000526691.5
ENST00000531691.5
ENST00000526390.5
ENST00000531689.5
thioredoxin reductase 1
chr1_-_150876571 0.30 ENST00000354396.6
ENST00000358595.10
ENST00000505755.5
aryl hydrocarbon receptor nuclear translocator
chr20_+_45812632 0.30 ENST00000335046.7
ENST00000356455.9
ENST00000243893.10
ubiquitin conjugating enzyme E2 C
chr6_+_132538290 0.29 ENST00000434551.2
trace amine associated receptor 9
chr3_-_186570308 0.29 ENST00000446782.5
TBCC domain containing 1
chr9_-_4666347 0.29 ENST00000381890.9
ENST00000682582.1
spermatogenesis associated 6 like
chr1_-_197146620 0.28 ENST00000367409.9
ENST00000680265.1
assembly factor for spindle microtubules
chr11_-_13495984 0.28 ENST00000282091.6
parathyroid hormone
chr3_+_148991408 0.28 ENST00000627418.2
ENST00000296048.10
ENST00000483267.5
ENST00000345003.9
ENST00000484197.5
glycogenin 1
chr12_-_120529140 0.28 ENST00000552443.5
ENST00000547736.1
ENST00000288532.11
ENST00000445328.6
ENST00000547943.5
coenzyme Q5, methyltransferase
chr10_+_89701653 0.28 ENST00000447580.1
kinesin family member 20B
chr4_-_145180496 0.27 ENST00000447906.8
OTU deubiquitinase 4
chr22_-_28741783 0.27 ENST00000439200.5
ENST00000405598.5
ENST00000398017.3
ENST00000649563.1
ENST00000650281.1
ENST00000425190.7
ENST00000404276.6
ENST00000650233.1
ENST00000348295.7
ENST00000382580.6
checkpoint kinase 2
chr1_+_23019415 0.27 ENST00000465864.2
ENST00000356634.7
ENST00000400181.9
lysine demethylase 1A
chr19_-_10116827 0.27 ENST00000593054.5
eukaryotic translation initiation factor 3 subunit G
chr20_+_45812665 0.27 ENST00000352551.9
ubiquitin conjugating enzyme E2 C
chr11_-_63614425 0.26 ENST00000415826.3
phospholipase A and acyltransferase 3
chr19_-_4717887 0.26 ENST00000599248.1
dipeptidyl peptidase 9
chr17_+_42288429 0.26 ENST00000676631.1
ENST00000677893.1
signal transducer and activator of transcription 5A
chr6_+_3258888 0.26 ENST00000380305.4
proteasome assembly chaperone 4
chrX_-_21658324 0.26 ENST00000379499.3
kelch like family member 34
chr15_+_76336755 0.25 ENST00000290759.9
ISL LIM homeobox 2
chr17_+_47209035 0.25 ENST00000572316.5
ENST00000354968.5
ENST00000576874.5
ENST00000536623.6
myosin light chain 4
chr6_+_36197356 0.25 ENST00000446974.1
ENST00000454960.1
bromodomain and PHD finger containing 3
chr19_+_35855838 0.24 ENST00000586102.7
kirre like nephrin family adhesion molecule 2
chr12_+_7711418 0.24 ENST00000345088.3
developmental pluripotency associated 3
chr10_-_97445850 0.24 ENST00000477692.6
ENST00000485122.6
ENST00000370886.9
ENST00000370885.8
ENST00000370902.8
ENST00000370884.5
exosome component 1
chr5_+_178204522 0.24 ENST00000506339.5
ENST00000358344.8
ENST00000355836.9
ENST00000514633.5
ENST00000515193.5
ENST00000506259.5
ENST00000504898.5
heterogeneous nuclear ribonucleoprotein A/B
chrX_-_140505058 0.24 ENST00000370536.5
SRY-box transcription factor 3
chr6_-_30113086 0.24 ENST00000376734.4
tripartite motif containing 31
chr11_+_77821105 0.24 ENST00000532481.5
adipogenesis associated Mth938 domain containing
chr11_-_95789474 0.24 ENST00000536839.1
family with sequence similarity 76 member B
chr3_+_102435015 0.24 ENST00000306176.5
ENST00000466937.2
zona pellucida like domain containing 1
chr11_-_111871530 0.23 ENST00000614444.4
ENST00000616540.5
ALG9 alpha-1,2-mannosyltransferase
chr8_+_7926337 0.23 ENST00000400120.3
zinc finger protein 705B
chr19_-_45782388 0.23 ENST00000458663.6
DM1 protein kinase
chrX_-_70049938 0.22 ENST00000276101.7
acyl-CoA wax alcohol acyltransferase 2
chr11_-_13496018 0.22 ENST00000529816.1
parathyroid hormone
chr1_-_161021096 0.22 ENST00000537746.1
ENST00000368026.11
F11 receptor
chr20_-_56392131 0.22 ENST00000422322.5
ENST00000371356.6
ENST00000451915.1
ENST00000347343.6
ENST00000395911.5
ENST00000395915.8
ENST00000395907.5
ENST00000441357.5
ENST00000456249.5
ENST00000420474.5
ENST00000395914.5
ENST00000312783.10
ENST00000395913.7
aurora kinase A
chr12_-_10826358 0.22 ENST00000240619.2
taste 2 receptor member 10
chr15_-_58279245 0.21 ENST00000558231.5
aldehyde dehydrogenase 1 family member A2
chr6_+_3258914 0.21 ENST00000438998.7
ENST00000419065.6
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
proteasome assembly chaperone 4
chr19_+_49487510 0.21 ENST00000679106.1
ENST00000621674.4
ENST00000391857.9
ENST00000678510.1
ENST00000467825.2
ribosomal protein L13a
chr6_+_63635792 0.21 ENST00000262043.8
ENST00000506783.5
ENST00000481385.6
ENST00000515594.5
ENST00000494284.6
PHD finger protein 3
chr20_+_45812576 0.21 ENST00000405520.5
ENST00000617055.4
ubiquitin conjugating enzyme E2 C
chr5_-_147906530 0.21 ENST00000318315.5
ENST00000515291.1
chromosome 5 open reading frame 46
chr3_+_98264244 0.21 ENST00000615035.3
ENST00000642105.1
olfactory receptor family 5 subfamily H member 6
chr12_+_51888217 0.21 ENST00000340970.8
ankyrin repeat domain 33
chr17_-_7263959 0.21 ENST00000571932.2
claudin 7
chr22_+_23980123 0.20 ENST00000621118.4
glutathione S-transferase theta 2 (gene/pseudogene)
chr1_-_197146688 0.20 ENST00000294732.11
assembly factor for spindle microtubules
chr11_-_111871271 0.19 ENST00000398006.6
ALG9 alpha-1,2-mannosyltransferase
chr11_-_122116215 0.19 ENST00000560104.2
BH3-like motif containing, cell death inducer
chr10_-_103351133 0.19 ENST00000369847.4
polycomb group ring finger 6
chr8_-_7385558 0.19 ENST00000400156.4
zinc finger protein 705G
chr11_-_95790348 0.19 ENST00000540054.5
family with sequence similarity 76 member B
chr11_-_62573846 0.18 ENST00000329251.5
eukaryotic translation elongation factor 1 gamma
chr12_+_51888083 0.18 ENST00000301190.11
ankyrin repeat domain 33
chr11_-_63614366 0.18 ENST00000323646.9
phospholipase A and acyltransferase 3
chr8_+_10095704 0.18 ENST00000382490.9
methionine sulfoxide reductase A
chr17_-_62806632 0.18 ENST00000583803.1
ENST00000456609.6
membrane associated ring-CH-type finger 10
chr10_-_5813387 0.17 ENST00000456041.5
ENST00000380181.7
ENST00000418688.5
ENST00000609712.1
ENST00000380191.9
GDP dissociation inhibitor 2
chr1_-_206202827 0.17 ENST00000431655.2
ENST00000367128.8
family with sequence similarity 72 member A
chr3_+_98149326 0.17 ENST00000437310.1
olfactory receptor family 5 subfamily H member 14
chr7_+_116222804 0.17 ENST00000393481.6
testin LIM domain protein
chr6_-_118934977 0.17 ENST00000425154.6
minichromosome maintenance 9 homologous recombination repair factor
chr3_-_120285215 0.17 ENST00000464295.6
G protein-coupled receptor 156
chr8_-_42768602 0.16 ENST00000534622.5
cholinergic receptor nicotinic alpha 6 subunit
chr12_+_53954870 0.16 ENST00000243103.4
homeobox C12
chr15_+_64387828 0.16 ENST00000261884.8
thyroid hormone receptor interactor 4
chr1_+_145095967 0.15 ENST00000400889.3
family with sequence similarity 72 member D
chr11_-_56614874 0.15 ENST00000641076.1
olfactory receptor family 5 subfamily M member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ISX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.3 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.6 4.3 GO:0048241 epinephrine transport(GO:0048241)
0.5 2.6 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.5 1.4 GO:0046333 octopamine biosynthetic process(GO:0006589) homoiothermy(GO:0042309) octopamine metabolic process(GO:0046333)
0.4 1.8 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.3 1.0 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.3 1.0 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 0.6 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.2 2.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 1.9 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 2.5 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.4 GO:0015847 putrescine transport(GO:0015847)
0.1 0.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.5 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.5 GO:0051795 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795)
0.1 0.3 GO:0090410 malonate catabolic process(GO:0090410)
0.1 0.3 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 2.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.5 GO:0090290 hormone-mediated apoptotic signaling pathway(GO:0008628) positive regulation of osteoclast proliferation(GO:0090290)
0.1 2.0 GO:0006069 ethanol oxidation(GO:0006069)
0.1 3.8 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 0.5 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.3 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.6 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.6 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.3 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.2 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.1 1.4 GO:0010226 response to lithium ion(GO:0010226)
0.1 0.8 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 0.2 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 0.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.2 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.1 3.0 GO:0007141 male meiosis I(GO:0007141)
0.1 0.4 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.9 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.4 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 1.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.4 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 0.9 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.4 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.4 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 1.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 1.0 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.4 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.7 GO:0002934 desmosome organization(GO:0002934)
0.0 0.4 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 1.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.6 GO:0045176 apical protein localization(GO:0045176)
0.0 1.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 2.0 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.2 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.7 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.9 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.9 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.8 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0006554 lysine catabolic process(GO:0006554)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.4 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0 1.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0034657 GID complex(GO:0034657)
0.1 0.4 GO:1990923 PET complex(GO:1990923)
0.1 1.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 1.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 8.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.5 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.4 GO:0035976 AP1 complex(GO:0035976)
0.0 0.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0044207 eukaryotic 48S preinitiation complex(GO:0033290) translation initiation ternary complex(GO:0044207)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 2.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 3.1 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 2.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.3 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.5 2.6 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.5 1.4 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.4 8.3 GO:0043295 glutathione binding(GO:0043295)
0.4 1.8 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.3 1.9 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.3 1.0 GO:0033265 choline binding(GO:0033265)
0.2 2.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2 1.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.4 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 3.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.4 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 2.0 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.3 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.1 0.3 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1 1.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 0.4 GO:0034584 piRNA binding(GO:0034584)
0.1 1.0 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.4 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 2.5 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.3 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.3 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.8 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.2 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.3 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.3 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.2 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 2.1 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 4.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 1.0 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 1.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 2.5 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 6.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 3.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 8.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 2.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 3.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling