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Illumina Body Map 2 (GSE30611)
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Results for JUN
Z-value: 2.03
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Transcription factors associated with JUN
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| JUN | hg38_v1_chr1_-_58784035_58784054 | 0.02 | 9.2e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of JUN
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 36.4 | GO:0007283 | spermatogenesis(GO:0007283) |
| 0.1 | 25.6 | GO:0007286 | spermatid development(GO:0007286) |
| 1.5 | 25.1 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.1 | 20.5 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.3 | 13.9 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.5 | 13.4 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
| 0.2 | 12.1 | GO:0030317 | sperm motility(GO:0030317) |
| 1.4 | 9.9 | GO:0007343 | egg activation(GO:0007343) |
| 1.5 | 9.1 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
| 0.0 | 8.9 | GO:0042742 | defense response to bacterium(GO:0042742) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 26.4 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.1 | 19.6 | GO:0031514 | motile cilium(GO:0031514) |
| 5.3 | 15.8 | GO:0033150 | cytoskeletal calyx(GO:0033150) |
| 0.9 | 13.9 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.3 | 11.8 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 1.8 | 10.9 | GO:0002081 | outer acrosomal membrane(GO:0002081) |
| 0.8 | 9.8 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.5 | 8.4 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.1 | 7.8 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 1.0 | 6.7 | GO:0031523 | Myb complex(GO:0031523) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 25.1 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.1 | 22.6 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.1 | 21.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 12.7 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 12.0 | GO:0003779 | actin binding(GO:0003779) |
| 0.1 | 7.1 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 7.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 6.8 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.4 | 6.7 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.0 | 6.1 | GO:0005525 | GTP binding(GO:0005525) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.5 | PID E2F PATHWAY | E2F transcription factor network |
| 0.2 | 5.8 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.1 | 5.5 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 5.2 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.1 | 4.8 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.1 | 3.8 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 3.6 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 3.4 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.1 | 3.1 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 2.8 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 10.5 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.2 | 8.4 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.2 | 7.9 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 4.9 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 4.5 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.1 | 3.8 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 3.8 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 0.2 | 3.7 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 3.4 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 3.3 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |