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Illumina Body Map 2 (GSE30611)

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Results for JUN

Z-value: 2.03

Motif logo

Transcription factors associated with JUN

Gene Symbol Gene ID Gene Info
ENSG00000177606.8 Jun proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
JUNhg38_v1_chr1_-_58784035_587840540.029.2e-01Click!

Activity profile of JUN motif

Sorted Z-values of JUN motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_18738102 13.90 ENST00000317658.5
capping actin protein of muscle Z-line subunit alpha 3
chr14_+_21030201 12.46 ENST00000321760.11
ENST00000460647.6
ENST00000530140.6
ENST00000472458.5
tubulin polymerization promoting protein family member 2
chr1_+_33864071 11.46 ENST00000681531.1
high mobility group box 4
chr12_-_18738006 9.87 ENST00000266505.12
ENST00000543242.5
ENST00000539072.5
ENST00000541966.5
ENST00000648272.1
phospholipase C zeta 1
chr2_+_231592858 9.53 ENST00000313965.4
testis expressed 44
chr1_+_153203424 9.31 ENST00000368747.2
late cornified envelope like proline rich 1
chr13_+_111320634 9.01 ENST00000283547.2
testis expressed 29
chr18_+_57147065 8.89 ENST00000585477.2
biorientation of chromosomes in cell division 1 like 2
chr9_+_108862255 8.43 ENST00000333999.5
actin like 7A
chr2_+_46479565 8.33 ENST00000434431.2
transmembrane protein 247
chr2_+_170783781 8.11 ENST00000409885.1
glutamate rich 2
chr19_+_48606732 8.08 ENST00000321762.3
sperm acrosome associated 4
chr3_-_51875597 8.02 ENST00000446461.2
IQ motif containing F5
chr5_-_113434978 7.89 ENST00000390666.4
testis specific serine kinase 1B
chr1_+_40247926 7.09 ENST00000372766.4
transmembrane and coiled-coil domains 2
chr10_+_22345445 6.84 ENST00000376603.6
ENST00000456231.6
ENST00000376624.8
ENST00000313311.10
ENST00000435326.5
sperm associated antigen 6
chr20_-_31390580 6.83 ENST00000339144.3
ENST00000376321.4
defensin beta 119
chr9_-_108855978 6.68 ENST00000374667.5
actin like 7B
chr12_+_48482492 6.67 ENST00000548364.7
chromosome 12 open reading frame 54
chr20_+_56524744 6.35 ENST00000371328.5
family with sequence similarity 209 member A
chr9_+_36169382 6.32 ENST00000335119.4
calicin
chr2_-_27139395 6.00 ENST00000432962.2
ENST00000335524.7
proline rich 30
chr22_+_19131271 5.97 ENST00000399635.4
testis specific serine kinase 2
chr1_+_178513103 5.97 ENST00000319416.7
ENST00000367643.7
ENST00000367642.3
ENST00000367641.7
ENST00000367639.1
testis expressed 35
chr19_-_50476725 5.94 ENST00000595790.5
family with sequence similarity 71 member E1
chr12_-_88029385 5.93 ENST00000298699.7
ENST00000550553.5
chromosome 12 open reading frame 50
chr6_+_42155399 5.85 ENST00000623004.2
ENST00000372963.4
ENST00000654459.1
GUCA1A neighbor
guanylate cyclase activator 1A
chr11_-_66026473 5.60 ENST00000312106.6
cation channel sperm associated 1
chr11_-_5509929 5.58 ENST00000311659.5
ENST00000445998.1
ubiquilin 3
chr1_+_110112428 5.57 ENST00000334179.5
ubiquitin like 4B
chr19_-_4902885 5.49 ENST00000650722.2
arrestin domain containing 5
chr14_+_21030509 5.48 ENST00000481535.5
tubulin polymerization promoting protein family member 2
chr1_-_75932392 5.43 ENST00000284142.7
ankyrin repeat and SOCS box containing 17
chr5_+_119629552 5.41 ENST00000613773.4
ENST00000620555.4
ENST00000515256.5
ENST00000509264.1
family with sequence similarity 170 member A
chrX_+_103710907 5.34 ENST00000319560.7
transmembrane protein 31
chr19_+_43716070 5.34 ENST00000244314.6
immunity related GTPase cinema
chr19_-_4902854 5.33 ENST00000381781.2
arrestin domain containing 5
chr17_-_35943707 5.25 ENST00000615905.5
lysozyme like 6
chr3_-_123980727 5.17 ENST00000620893.4
rhophilin associated tail protein 1
chr12_-_13103637 5.16 ENST00000545401.5
ENST00000432710.6
ENST00000351606.10
ENST00000651961.1
ENST00000542415.5
germ cell associated 1
chr9_+_102995308 5.10 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
cylicin 2
chr9_-_27297128 4.92 ENST00000537675.5
ENST00000380031.2
equatorin
chr5_+_76609091 4.92 ENST00000514001.5
ENST00000396234.7
ENST00000509074.5
ENST00000502745.5
IQ motif containing GTPase activating protein 2
chr3_-_196211386 4.91 ENST00000296326.8
zinc finger DHHC-type palmitoyltransferase 19
chr7_+_142939343 4.85 ENST00000458732.1
ENST00000409607.5
LLLL and CFNLAS motif containing 1
chr3_-_51903341 4.74 ENST00000310914.10
IQ motif containing F1
chr3_+_44799187 4.64 ENST00000425755.5
kinesin family member 15
chr9_-_34397800 4.61 ENST00000297623.7
chromosome 9 open reading frame 24
chr9_-_110337808 4.58 ENST00000374510.8
ENST00000374507.4
ENST00000423740.7
ENST00000374511.7
thioredoxin domain containing 8
chr17_-_35943662 4.57 ENST00000618542.4
lysozyme like 6
chr3_+_51829417 4.54 ENST00000440739.3
ENST00000444293.5
IQ motif containing F3
chr12_-_49605634 4.50 ENST00000257894.2
family with sequence similarity 186 member B
chr19_+_35533436 4.47 ENST00000222286.9
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr20_-_1557679 4.47 ENST00000381621.5
ENST00000381623.4
signal regulatory protein delta
chrX_+_83861126 4.41 ENST00000621735.4
ENST00000329312.5
cylicin 1
chr1_+_173635332 4.26 ENST00000417563.3
testis expressed 50
chr16_-_11273610 4.23 ENST00000327157.4
protamine 3
chrY_+_18546691 4.21 ENST00000309834.8
ENST00000307393.3
ENST00000382856.2
heat shock transcription factor Y-linked 1
chr9_-_27297143 4.20 ENST00000380032.8
equatorin
chrX_-_139965510 4.16 ENST00000370540.2
chromosome X open reading frame 66
chr19_-_35228699 4.16 ENST00000324675.3
family with sequence similarity 187 member B
chr19_-_48746797 4.12 ENST00000602105.1
ENST00000332955.7
izumo sperm-egg fusion 1
chr19_+_43716095 4.10 ENST00000596627.1
immunity related GTPase cinema
chr19_-_8698789 4.10 ENST00000324436.5
actin like 9
chr2_+_3658193 4.05 ENST00000252505.4
allantoicase
chr17_-_78903193 3.99 ENST00000322630.3
ENST00000586713.5
CEP295 N-terminal like
chr1_-_119896489 3.98 ENST00000369400.2
ADAM metallopeptidase domain 30
chr3_+_51817596 3.97 ENST00000456080.5
novel protein
chr19_-_8698705 3.87 ENST00000612068.1
actin like 9
chr22_-_43862480 3.84 ENST00000330884.9
sulfotransferase family 4A member 1
chr22_+_50738198 3.78 ENST00000216139.10
ENST00000529621.1
acrosin
chr14_-_44507269 3.75 ENST00000340446.5
fibrous sheath CABYR binding protein
chr20_-_45791865 3.69 ENST00000243938.9
WAP four-disulfide core domain 3
chr19_-_55363243 3.69 ENST00000424985.3
family with sequence similarity 71 member E2
chr13_+_45702306 3.69 ENST00000533564.1
ENST00000310521.6
chibby family member 2
chr20_-_31390483 3.66 ENST00000376315.2
defensin beta 119
chr7_+_151956440 3.64 ENST00000392800.7
ENST00000616416.4
polypeptide N-acetylgalactosaminyltransferase like 5
chr6_+_96562548 3.64 ENST00000541107.5
ENST00000326771.2
four and a half LIM domains 5
chr13_+_45702411 3.59 ENST00000610924.1
chibby family member 2
chrX_-_42778155 3.58 ENST00000378131.4
PPP1R2C family member C
chr1_+_64203610 3.50 ENST00000371077.10
ENST00000611228.4
ubiquitin conjugating enzyme E2 U
chr7_+_73861148 3.47 ENST00000320531.3
transmembrane protein 270
chrX_+_152698767 3.47 ENST00000417212.5
ENST00000598245.2
ENST00000370278.4
MAGE family member A3
chr20_+_43667019 3.45 ENST00000396863.8
MYB proto-oncogene like 2
chr1_-_26374513 3.43 ENST00000455900.5
zinc finger protein 683
chr11_-_28108109 3.40 ENST00000263181.7
kinesin family member 18A
chr17_+_41837817 3.36 ENST00000438813.1
ENST00000293303.5
kelch like family member 10
chr17_+_32991844 3.33 ENST00000269053.8
sperm acrosome associated 3
chr20_+_43667105 3.29 ENST00000217026.5
MYB proto-oncogene like 2
chr1_+_34166883 3.22 ENST00000373374.7
chromosome 1 open reading frame 94
chrX_+_93674194 3.21 ENST00000332647.5
ENST00000683942.1
family with sequence similarity 133 member A
chr1_-_162376841 3.20 ENST00000367935.10
spermatogenesis associated 46
chr15_+_75724034 3.18 ENST00000332145.3
outer dense fiber of sperm tails 3 like 1
chr17_-_8758559 3.15 ENST00000328794.10
speedy/RINGO cell cycle regulator family member E4
chr17_+_63484840 3.14 ENST00000290863.10
ENST00000413513.7
angiotensin I converting enzyme
chr20_+_56533246 3.12 ENST00000371325.1
family with sequence similarity 209 member B
chr4_+_174918355 3.10 ENST00000505141.5
ENST00000359240.7
ENST00000615367.4
ENST00000445694.5
ENST00000618444.1
ADAM metallopeptidase domain 29
chr19_-_45584810 3.07 ENST00000323060.3
outer mitochondrial membrane lipid metabolism regulator OPA3
chr17_-_65826445 3.04 ENST00000317442.12
centrosomal protein 112
chrX_+_154884972 3.01 ENST00000620016.2
H2A.B variant histone 1
chr11_-_95232514 3.00 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
sestrin 3
chr2_+_148875214 2.99 ENST00000435030.6
ENST00000677891.1
ENST00000677843.1
ENST00000678056.1
ENST00000677280.1
kinesin family member 5C
chr9_-_34665985 2.96 ENST00000416454.5
ENST00000544078.2
ENST00000421828.7
ENST00000423809.5
novel protein
chr1_+_44674688 2.96 ENST00000418644.5
ENST00000458657.6
ENST00000535358.6
ENST00000441519.5
ENST00000445071.5
armadillo like helical domain containing 1
chr4_+_127880876 2.96 ENST00000270861.10
ENST00000515069.5
ENST00000513090.5
ENST00000507249.5
polo like kinase 4
chr4_-_103019634 2.95 ENST00000510559.1
ENST00000296422.12
ENST00000394789.7
solute carrier family 9 member B1
chrY_+_3579067 2.95 ENST00000321217.5
ENST00000559055.2
TGFB induced factor homeobox 2 like Y-linked
chr2_+_97669739 2.95 ENST00000599501.6
ENST00000627399.3
ENST00000627284.2
ENST00000599435.5
ENST00000597654.5
ENST00000598737.5
chromosome 2 open reading frame 92
chr8_-_18854355 2.95 ENST00000519851.5
pleckstrin and Sec7 domain containing 3
chr21_-_43659460 2.92 ENST00000443485.1
ENST00000291560.7
heat shock transcription factor 2 binding protein
chr12_-_4645150 2.91 ENST00000536414.3
A-kinase anchoring protein 3
chr1_+_54641754 2.91 ENST00000339553.9
ENST00000421030.7
maestro heat like repeat family member 7
chr1_+_54641806 2.88 ENST00000409996.5
maestro heat like repeat family member 7
chr9_-_19033200 2.84 ENST00000380534.9
ENST00000380530.1
stabilizer of axonemal microtubules 1
chr1_-_31798755 2.83 ENST00000452755.6
SPOC domain containing 1
chrX_+_155380709 2.79 ENST00000354514.6
H2A.B variant histone 2
chr15_-_90994494 2.78 ENST00000559811.1
ENST00000442656.6
ENST00000557905.5
ENST00000394249.8
protein regulator of cytokinesis 1
chr2_+_98245427 2.78 ENST00000614454.1
von Willebrand factor A domain containing 3B
chr22_+_50089879 2.77 ENST00000545383.5
ENST00000262794.10
Mov10 like RISC complex RNA helicase 1
chrX_+_89921903 2.76 ENST00000283891.6
ENST00000561129.2
TGFB induced factor homeobox 2 like X-linked
chr4_+_93203949 2.74 ENST00000512631.1
glutamate ionotropic receptor delta type subunit 2
chr15_+_74236322 2.72 ENST00000398814.8
coiled-coil domain containing 33
chr6_+_143864458 2.72 ENST00000237275.9
zinc finger C2HC-type containing 1B
chr17_+_32991867 2.71 ENST00000394638.1
sperm acrosome associated 3
chr12_-_4645188 2.71 ENST00000540967.5
A-kinase anchoring protein 3
chr12_-_57488726 2.68 ENST00000550288.6
ENST00000393797.7
Rho GTPase activating protein 9
chr1_+_1179676 2.68 ENST00000379288.3
tubulin tyrosine ligase like 10
chr20_+_23491090 2.66 ENST00000449810.5
ENST00000246012.2
cystatin 8
chr1_+_77532100 2.66 ENST00000478255.1
adenylate kinase 5
chr2_-_240820205 2.63 ENST00000647731.1
ENST00000648680.1
ENST00000649306.1
ENST00000648129.1
ENST00000498729.9
ENST00000320389.12
ENST00000648364.1
ENST00000647885.1
ENST00000404283.9
ENST00000649096.1
kinesin family member 1A
chr2_+_27537380 2.62 ENST00000447166.2
chromosome 2 open reading frame 16
chr3_+_10026409 2.60 ENST00000287647.7
ENST00000676013.1
ENST00000675286.1
ENST00000419585.5
FA complementation group D2
chr20_-_32536383 2.59 ENST00000375678.7
nucleolar protein 4 like
chr1_+_85062304 2.57 ENST00000326813.12
ENST00000528899.5
ENST00000294664.11
dynein axonemal intermediate chain 3
chr7_+_151956379 2.56 ENST00000431418.6
polypeptide N-acetylgalactosaminyltransferase like 5
chr3_+_158571215 2.56 ENST00000498592.6
ENST00000478894.7
myeloid leukemia factor 1
chr3_+_158571171 2.54 ENST00000484955.5
ENST00000359117.9
ENST00000619577.5
ENST00000471745.5
ENST00000477042.6
ENST00000650753.1
ENST00000651984.1
ENST00000355893.11
ENST00000466246.7
ENST00000469452.5
ENST00000482628.5
myeloid leukemia factor 1
chr11_-_62832803 2.54 ENST00000636508.1
testis expressed 54
chr2_+_73784189 2.53 ENST00000409561.1
chromosome 2 open reading frame 78
chr14_+_76826372 2.52 ENST00000393774.7
ENST00000555189.1
leucine rich repeat containing 74A
chrX_-_152992195 2.52 ENST00000361887.5
ENST00000452693.5
ENST00000439251.3
PNMA family member 5
chr14_+_93997296 2.51 ENST00000636493.2
coiled-coil domain containing 197
chr5_+_138337511 2.48 ENST00000434981.6
family with sequence similarity 53 member C
chr16_+_30023198 2.47 ENST00000681219.1
ENST00000300575.6
chromosome 16 open reading frame 92
chr13_-_60163764 2.46 ENST00000377908.6
ENST00000400319.5
ENST00000400320.5
ENST00000267215.8
diaphanous related formin 3
chr3_-_196568575 2.44 ENST00000429115.1
WD repeat domain 53
chr20_+_17699942 2.40 ENST00000427254.1
ENST00000377805.7
BANF family member 2
chr12_-_49605608 2.35 ENST00000551047.5
family with sequence similarity 186 member B
chr1_+_54641816 2.32 ENST00000395690.6
maestro heat like repeat family member 7
chr11_-_9003994 2.32 ENST00000309166.8
ENST00000525100.1
ENST00000531090.5
nuclear receptor interacting protein 3
chr11_+_6205549 2.31 ENST00000316375.3
chromosome 11 open reading frame 42
chr1_-_25906931 2.24 ENST00000357865.6
stathmin 1
chr20_+_17699960 2.23 ENST00000246090.6
BANF family member 2
chr6_-_119078642 2.20 ENST00000621231.4
ENST00000338891.12
family with sequence similarity 184 member A
chr1_-_26374452 2.19 ENST00000416125.1
zinc finger protein 683
chr3_-_196568596 2.19 ENST00000433160.1
WD repeat domain 53
chr16_+_11249617 2.18 ENST00000572173.1
RecQ mediated genome instability 2
chr2_+_37950476 2.16 ENST00000402091.3
regulator of microtubule dynamics 2
chr8_+_42338477 2.15 ENST00000518925.5
ENST00000265421.9
DNA polymerase beta
chr16_-_3495472 2.15 ENST00000399645.3
chromosome 16 open reading frame 90
chr3_+_158571153 2.15 ENST00000491767.6
ENST00000618075.4
myeloid leukemia factor 1
chr13_+_111115235 2.15 ENST00000375739.6
ENST00000375741.6
Rho guanine nucleotide exchange factor 7
chr1_+_32362537 2.14 ENST00000373534.4
testis specific serine kinase 3
chr1_+_1001002 2.13 ENST00000624697.4
ENST00000624652.1
ISG15 ubiquitin like modifier
chr7_-_37916807 2.13 ENST00000436072.7
secreted frizzled related protein 4
chr16_-_3495484 2.12 ENST00000437192.8
chromosome 16 open reading frame 90
chr19_-_50476838 2.11 ENST00000600100.6
family with sequence similarity 71 member E1
chrY_-_18773686 2.11 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
heat shock transcription factor Y-linked 2
chr3_-_196568542 2.10 ENST00000332629.7
WD repeat domain 53
chr14_-_76826229 2.09 ENST00000557497.1
angel homolog 1
chr22_+_50090028 2.07 ENST00000395858.7
Mov10 like RISC complex RNA helicase 1
chr2_+_196713117 2.06 ENST00000409270.5
coiled-coil domain containing 150
chr11_-_64879675 2.05 ENST00000359393.6
ENST00000433803.1
ENST00000411683.1
EH domain containing 1
chr12_-_122896066 2.05 ENST00000267202.7
ENST00000535765.5
VPS37B subunit of ESCRT-I
chr1_+_92168915 2.03 ENST00000637221.2
BTB domain containing 8
chr7_+_129144691 2.02 ENST00000486685.3
tetraspanin 33
chr1_+_173868350 2.02 ENST00000427304.5
ENST00000367702.1
zinc finger and BTB domain containing 37
chr18_-_5540389 2.01 ENST00000584670.1
ENST00000582703.5
ENST00000580179.2
erythrocyte membrane protein band 4.1 like 3
chr3_-_182985926 1.99 ENST00000487822.5
ENST00000460412.6
ENST00000469954.5
defective in cullin neddylation 1 domain containing 1
chr9_+_121144053 1.99 ENST00000431571.5
centriolin
chr17_-_75153826 1.98 ENST00000481647.5
ENST00000470924.5
Jupiter microtubule associated homolog 1
chr11_-_75490725 1.97 ENST00000529721.5
glycerophosphodiester phosphodiesterase domain containing 5
chr4_-_103198371 1.96 ENST00000611174.4
ENST00000380026.8
centromere protein E
chr12_-_31729092 1.96 ENST00000541931.5
ENST00000535408.5
antagonist of mitotic exit network 1 homolog
chr16_+_68023249 1.96 ENST00000358896.10
ENST00000568099.6
dihydrouridine synthase 2
chr19_+_1954633 1.95 ENST00000589350.2
casein kinase 1 gamma 2
chr2_+_37950432 1.95 ENST00000407257.5
ENST00000417700.6
ENST00000234195.7
ENST00000442857.5
regulator of microtubule dynamics 2
chr16_+_68023276 1.95 ENST00000567100.5
ENST00000565263.6
ENST00000432752.5
ENST00000569289.5
ENST00000564781.1
dihydrouridine synthase 2
chrX_+_153056458 1.95 ENST00000593810.3
PNMA family member 3
chr16_+_1989949 1.93 ENST00000248121.7
ENST00000618464.1
synaptogyrin 3
chr9_+_127716073 1.92 ENST00000373289.4
tetratricopeptide repeat domain 16
chr7_-_122304738 1.91 ENST00000442488.7
FEZ family zinc finger 1
chr17_+_4739791 1.90 ENST00000433935.6
zinc finger MYND-type containing 15
chr9_-_114682061 1.89 ENST00000612244.5
testis expressed 48
chr5_-_176537361 1.88 ENST00000274811.9
ring finger protein 44
chr5_-_147906530 1.86 ENST00000318315.5
ENST00000515291.1
chromosome 5 open reading frame 46
chr19_-_56314788 1.83 ENST00000592509.5
ENST00000592679.5
ENST00000683990.1
ENST00000588442.5
ENST00000593106.5
ENST00000587492.5
zinc finger and SCAN domain containing 5A
chr8_+_38386433 1.81 ENST00000297720.9
ENST00000524874.5
ENST00000379957.9
ENST00000523983.6
leucine zipper and EF-hand containing transmembrane protein 2
chr2_+_11724343 1.81 ENST00000396098.5
lipin 1
chrX_+_153056408 1.80 ENST00000619635.1
PNMA family member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of JUN

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 9.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
1.5 25.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.4 9.9 GO:0007343 egg activation(GO:0007343)
1.1 8.5 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
1.0 3.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
1.0 4.0 GO:0043605 cellular amide catabolic process(GO:0043605)
0.9 4.7 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.9 5.6 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826) regulation of extrathymic T cell differentiation(GO:0033082)
0.9 2.7 GO:0006173 dADP biosynthetic process(GO:0006173)
0.7 3.7 GO:0006288 base-excision repair, base-free sugar-phosphate removal(GO:0006286) base-excision repair, DNA ligation(GO:0006288)
0.7 2.8 GO:0009631 cold acclimation(GO:0009631)
0.7 2.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.7 2.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.6 3.8 GO:0007341 penetration of zona pellucida(GO:0007341)
0.6 2.4 GO:0072560 type B pancreatic cell maturation(GO:0072560)
0.6 3.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.6 3.4 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.5 3.7 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.5 13.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.5 2.3 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.5 2.7 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.4 1.8 GO:1990108 protein linear deubiquitination(GO:1990108)
0.4 2.2 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.4 3.4 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.4 1.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.4 3.0 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.4 3.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.4 0.4 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.4 3.9 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.4 1.5 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.4 1.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.4 1.4 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.4 1.8 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.4 4.6 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.3 1.7 GO:0061113 pancreas morphogenesis(GO:0061113)
0.3 1.0 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.3 1.4 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.3 1.0 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.3 0.9 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.3 0.6 GO:0090427 activation of meiosis(GO:0090427)
0.3 1.5 GO:0035696 monocyte extravasation(GO:0035696)
0.3 1.2 GO:0061163 endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650)
0.3 13.9 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.3 1.7 GO:0080154 regulation of fertilization(GO:0080154)
0.3 1.7 GO:0042989 sequestering of actin monomers(GO:0042989)
0.3 0.8 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.3 5.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.3 2.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) positive regulation of long term synaptic depression(GO:1900454)
0.3 1.3 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.3 1.0 GO:0003290 atrial septum secundum morphogenesis(GO:0003290)
0.3 0.8 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.2 0.7 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.2 7.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 1.4 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.2 3.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 2.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.2 2.7 GO:0018094 protein polyglycylation(GO:0018094)
0.2 4.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 1.5 GO:0030035 microspike assembly(GO:0030035)
0.2 2.6 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.2 1.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 0.6 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.2 1.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 1.6 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.2 1.5 GO:0006642 triglyceride mobilization(GO:0006642)
0.2 0.5 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.2 0.5 GO:0036451 cap mRNA methylation(GO:0036451)
0.2 2.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 3.8 GO:0044458 motile cilium assembly(GO:0044458)
0.2 1.4 GO:0032621 interleukin-18 production(GO:0032621)
0.2 12.1 GO:0030317 sperm motility(GO:0030317)
0.2 0.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 3.0 GO:0038203 TORC2 signaling(GO:0038203)
0.1 20.5 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.9 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 4.1 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.7 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 3.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 25.6 GO:0007286 spermatid development(GO:0007286)
0.1 0.5 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 5.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 0.5 GO:1900222 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222)
0.1 1.0 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 2.9 GO:0045116 protein neddylation(GO:0045116)
0.1 0.6 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 0.4 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.1 2.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.6 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 1.3 GO:0032364 oxygen homeostasis(GO:0032364)
0.1 1.5 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 1.0 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.5 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.9 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.0 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.5 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 4.0 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 1.2 GO:0097324 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.7 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 0.7 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 1.9 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1 0.8 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1 0.7 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.1 1.0 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.8 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.3 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 5.8 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.3 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 1.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.6 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.1 0.5 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 0.5 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 1.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 3.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 36.4 GO:0007283 spermatogenesis(GO:0007283)
0.1 0.3 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.1 1.9 GO:0030488 tRNA methylation(GO:0030488)
0.1 2.2 GO:0000732 strand displacement(GO:0000732)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 1.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 5.7 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525)
0.1 5.0 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1 1.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.3 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 3.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.2 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.4 GO:0045136 development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543)
0.0 0.5 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 2.2 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.7 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.6 GO:0051665 membrane raft localization(GO:0051665)
0.0 3.2 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.5 GO:0007135 meiosis II(GO:0007135)
0.0 3.5 GO:0010955 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.7 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 1.3 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 1.2 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.7 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 4.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 5.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 1.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.0 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.7 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:1904124 negative regulation of norepinephrine secretion(GO:0010700) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 1.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.7 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.5 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 1.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.5 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 3.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 1.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 1.1 GO:0051693 actin filament capping(GO:0051693)
0.0 0.8 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.7 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 8.9 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.9 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 1.5 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.3 GO:2000111 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) positive regulation of myeloid cell apoptotic process(GO:0033034) positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.4 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.4 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:1901552 negative regulation of excitatory postsynaptic potential(GO:0090394) positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.8 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.8 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 2.0 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 1.3 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.8 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.1 GO:1904207 chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:0070365 hepatocyte differentiation(GO:0070365)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 15.8 GO:0033150 cytoskeletal calyx(GO:0033150)
1.9 3.8 GO:0043159 acrosomal matrix(GO:0043159)
1.8 10.9 GO:0002081 outer acrosomal membrane(GO:0002081)
1.0 6.7 GO:0031523 Myb complex(GO:0031523)
0.9 13.9 GO:0008290 F-actin capping protein complex(GO:0008290)
0.8 9.8 GO:0097524 sperm plasma membrane(GO:0097524)
0.8 4.6 GO:0005873 plus-end kinesin complex(GO:0005873)
0.5 4.8 GO:0071546 pi-body(GO:0071546)
0.5 3.7 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.5 8.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.4 1.7 GO:0097545 axonemal outer doublet(GO:0097545)
0.4 5.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.4 5.6 GO:0036128 CatSper complex(GO:0036128)
0.4 1.3 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 2.7 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.3 3.0 GO:0098536 deuterosome(GO:0098536)
0.3 2.9 GO:0033503 HULC complex(GO:0033503)
0.3 1.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.3 11.8 GO:0002080 acrosomal membrane(GO:0002080)
0.3 2.8 GO:0005879 axonemal microtubule(GO:0005879)
0.3 2.1 GO:0032021 NELF complex(GO:0032021)
0.2 1.4 GO:0044393 microspike(GO:0044393)
0.2 2.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 3.0 GO:0005828 kinetochore microtubule(GO:0005828)
0.2 0.8 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 26.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 3.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 3.1 GO:0044292 dendrite terminus(GO:0044292)
0.2 1.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 0.7 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.2 4.2 GO:0000786 nucleosome(GO:0000786)
0.2 5.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.2 3.0 GO:0035253 ciliary rootlet(GO:0035253)
0.2 2.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 3.0 GO:0061700 GATOR2 complex(GO:0061700)
0.1 3.0 GO:0060077 inhibitory synapse(GO:0060077)
0.1 2.1 GO:0000322 storage vacuole(GO:0000322)
0.1 0.5 GO:0071757 hexameric IgM immunoglobulin complex(GO:0071757)
0.1 0.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 2.0 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 19.6 GO:0031514 motile cilium(GO:0031514)
0.1 1.2 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.9 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 2.8 GO:0070938 contractile ring(GO:0070938)
0.1 3.5 GO:0033270 paranode region of axon(GO:0033270)
0.1 1.2 GO:0001940 male pronucleus(GO:0001940)
0.1 6.5 GO:0001533 cornified envelope(GO:0001533)
0.1 1.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 1.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 1.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 2.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 5.2 GO:0031941 filamentous actin(GO:0031941)
0.1 1.3 GO:0008091 spectrin(GO:0008091)
0.1 0.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.0 GO:0070187 telosome(GO:0070187)
0.1 0.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 7.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 0.9 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 2.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 1.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.6 GO:0097542 ciliary tip(GO:0097542)
0.0 4.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.7 GO:0005871 kinesin complex(GO:0005871)
0.0 1.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.9 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 2.1 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.8 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 2.0 GO:0031902 late endosome membrane(GO:0031902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 25.1 GO:0003796 lysozyme activity(GO:0003796)
0.9 3.8 GO:0004040 amidase activity(GO:0004040)
0.9 4.5 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.7 5.8 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.7 3.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.7 2.0 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.5 3.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.5 3.4 GO:0043515 kinetochore binding(GO:0043515)
0.4 6.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4 4.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.4 3.9 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.3 1.0 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.3 3.5 GO:0089720 caspase binding(GO:0089720)
0.3 1.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 2.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 4.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 1.4 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3 4.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 3.7 GO:0051525 NFAT protein binding(GO:0051525)
0.3 1.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 1.3 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.2 2.0 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.2 2.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 2.7 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.2 2.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.6 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2 1.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 0.6 GO:0031753 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.2 1.8 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.2 1.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 0.7 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.2 0.7 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.2 0.5 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.2 5.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 1.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 3.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 4.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 2.1 GO:0031386 protein tag(GO:0031386)
0.2 2.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.4 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.1 3.0 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.1 1.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 1.3 GO:0034711 inhibin binding(GO:0034711)
0.1 5.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 2.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 3.7 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 1.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 2.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.0 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 4.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.5 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 1.0 GO:0015180 hydrogen:amino acid symporter activity(GO:0005280) L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.4 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 2.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.0 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 1.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 2.5 GO:0097602 cullin family protein binding(GO:0097602)
0.1 7.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 3.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 21.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.3 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.1 0.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 2.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 4.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.8 GO:0033691 sialic acid binding(GO:0033691)
0.1 4.2 GO:0019894 kinesin binding(GO:0019894)
0.1 1.4 GO:0000150 recombinase activity(GO:0000150)
0.1 2.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 2.7 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1 2.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 6.8 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 22.6 GO:0000287 magnesium ion binding(GO:0000287)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 3.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 1.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 2.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.9 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 2.5 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.0 1.8 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.9 GO:0005522 profilin binding(GO:0005522)
0.0 7.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 1.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 12.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 2.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0004605 diacylglycerol cholinephosphotransferase activity(GO:0004142) phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 2.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 1.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.5 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.9 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.2 GO:0000049 tRNA binding(GO:0000049)
0.0 1.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 12.0 GO:0003779 actin binding(GO:0003779)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.5 GO:0043531 ADP binding(GO:0043531)
0.0 0.7 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 6.1 GO:0005525 GTP binding(GO:0005525)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 1.3 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.8 PID CONE PATHWAY Visual signal transduction: Cones
0.1 4.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 5.5 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.8 PID ATR PATHWAY ATR signaling pathway
0.0 2.8 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 5.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 6.5 PID E2F PATHWAY E2F transcription factor network
0.0 3.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 2.1 PID AURORA A PATHWAY Aurora A signaling
0.0 2.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 2.6 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 3.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.7 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 2.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 8.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 0.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.2 2.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 3.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 7.9 REACTOME KINESINS Genes involved in Kinesins
0.1 3.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 3.8 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 2.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 4.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 4.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 3.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 3.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 2.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 2.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 2.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.9 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins