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Illumina Body Map 2 (GSE30611)

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Results for KLF12

Z-value: 1.09

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Transcription factors associated with KLF12

Gene Symbol Gene ID Gene Info
ENSG00000118922.18 Kruppel like factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF12hg38_v1_chr13_-_74133892_74133941-0.373.6e-02Click!

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102530738 3.38 ENST00000260227.5
matrix metallopeptidase 7
chr17_+_1762012 3.19 ENST00000571360.5
serpin family F member 1
chr17_+_1762052 3.17 ENST00000254722.9
ENST00000576406.5
ENST00000571149.5
serpin family F member 1
chr6_+_31927683 3.05 ENST00000456570.5
novel complement component 2 (C2) and complement factor B (CFB) protein
chr3_-_49685090 2.94 ENST00000448220.5
macrophage stimulating 1
chr16_-_67944113 2.85 ENST00000264005.10
lecithin-cholesterol acyltransferase
chr2_-_219571241 2.78 ENST00000373876.5
ENST00000603926.5
ENST00000373873.8
ENST00000289656.3
obscurin like cytoskeletal adaptor 1
chr12_-_7088848 2.74 ENST00000649804.1
complement C1r
chr12_+_7060676 2.39 ENST00000617865.4
ENST00000402681.7
ENST00000360817.10
complement C1s
chr1_-_18902520 2.34 ENST00000538839.5
ENST00000290597.9
ENST00000375341.8
aldehyde dehydrogenase 4 family member A1
chr6_+_31927703 2.32 ENST00000418949.6
ENST00000299367.10
ENST00000383177.7
ENST00000477310.1
complement C2
novel complement component 2 (C2) and complement factor B (CFB) protein
chr14_+_63204436 2.28 ENST00000316754.8
ras homolog family member J
chr2_+_233636445 2.16 ENST00000344644.9
UDP glucuronosyltransferase family 1 member A10
chr2_-_21044063 2.08 ENST00000233242.5
apolipoprotein B
chr10_-_50885656 2.07 ENST00000374001.6
ENST00000395489.6
ENST00000282641.6
ENST00000395495.5
ENST00000373995.7
ENST00000414883.1
APOBEC1 complementation factor
chr12_-_95790755 2.07 ENST00000343702.9
ENST00000344911.8
netrin 4
chr11_+_117199363 1.98 ENST00000392951.9
ENST00000525531.5
ENST00000278968.10
transgelin
chr1_+_213987929 1.87 ENST00000498508.6
ENST00000366958.9
prospero homeobox 1
chr5_+_34656288 1.87 ENST00000265109.8
retinoic acid induced 14
chr2_+_233636502 1.82 ENST00000373445.1
UDP glucuronosyltransferase family 1 member A10
chr19_-_4338786 1.81 ENST00000601482.1
ENST00000600324.5
ENST00000594605.6
signal transducing adaptor family member 2
chr12_+_7061206 1.79 ENST00000423384.5
ENST00000413211.5
complement C1s
chr9_+_134641768 1.72 ENST00000371817.8
ENST00000618395.4
collagen type V alpha 1 chain
chr2_+_104854104 1.69 ENST00000361360.4
POU class 3 homeobox 3
chr2_+_168802610 1.68 ENST00000397206.6
ENST00000317647.12
ENST00000397209.6
nitric oxide synthase trafficking
chr4_-_74099187 1.67 ENST00000508487.3
C-X-C motif chemokine ligand 2
chr9_-_34637800 1.66 ENST00000680730.1
ENST00000477726.1
sigma non-opioid intracellular receptor 1
chr5_+_34656446 1.62 ENST00000428746.6
retinoic acid induced 14
chr9_-_34637719 1.62 ENST00000378892.5
ENST00000680277.1
ENST00000277010.9
ENST00000679597.1
ENST00000680244.1
sigma non-opioid intracellular receptor 1
chr10_-_89643870 1.61 ENST00000322191.10
ENST00000342512.3
pantothenate kinase 1
chr12_-_55727044 1.60 ENST00000548160.5
CD63 molecule
chr11_-_57322197 1.59 ENST00000532437.1
tankyrase 1 binding protein 1
chr16_+_46884675 1.51 ENST00000562132.5
ENST00000440783.2
glutamic--pyruvic transaminase 2
chr10_-_73641450 1.45 ENST00000359322.5
myozenin 1
chr11_-_16356538 1.44 ENST00000683767.1
SRY-box transcription factor 6
chr11_-_61580826 1.42 ENST00000540677.5
ENST00000542836.5
ENST00000542670.5
ENST00000535826.5
ENST00000545053.1
ENST00000539008.6
synaptotagmin 7
chr11_-_61581104 1.38 ENST00000263846.8
synaptotagmin 7
chr17_+_42853232 1.34 ENST00000617500.4
amine oxidase copper containing 3
chr7_-_27185223 1.34 ENST00000517402.1
ENST00000006015.4
homeobox A11
chr5_+_34656424 1.31 ENST00000513974.5
ENST00000512629.5
retinoic acid induced 14
chr3_+_46883337 1.30 ENST00000313049.9
parathyroid hormone 1 receptor
chr1_+_213988501 1.26 ENST00000261454.8
ENST00000435016.2
prospero homeobox 1
chr14_+_104724221 1.24 ENST00000330877.7
adenylosuccinate synthase 1
chr2_+_168802563 1.23 ENST00000445023.6
nitric oxide synthase trafficking
chr19_+_44777860 1.22 ENST00000341505.4
ENST00000647358.2
Cbl proto-oncogene C
chr3_+_194136138 1.21 ENST00000232424.4
hes family bHLH transcription factor 1
chr1_+_162366896 1.20 ENST00000420220.1
novel protein
chr12_-_56488350 1.19 ENST00000623608.3
ENST00000610413.4
glutaminase 2
chr16_+_28878382 1.19 ENST00000357084.7
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr17_-_42676980 1.18 ENST00000587627.1
ENST00000591022.6
ENST00000293349.10
pleckstrin homology, MyTH4 and FERM domain containing H3
chr5_+_53480619 1.16 ENST00000396947.7
ENST00000256759.8
follistatin
chr14_+_73950285 1.15 ENST00000334571.7
ENST00000554920.5
coenzyme Q6, monooxygenase
chr5_+_132369908 1.15 ENST00000435065.6
solute carrier family 22 member 5
chr16_+_28878480 1.13 ENST00000395503.9
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr12_-_55727080 1.12 ENST00000548898.5
ENST00000552067.5
CD63 molecule
chr7_+_37920602 1.12 ENST00000199448.9
ENST00000423717.1
ependymin related 1
chr10_-_79445617 1.11 ENST00000372336.4
zinc finger CCHC-type containing 24
chr11_-_72781858 1.11 ENST00000537947.5
StAR related lipid transfer domain containing 10
chr7_-_135748785 1.10 ENST00000338588.8
family with sequence similarity 180 member A
chr3_+_148791058 1.08 ENST00000491148.5
carboxypeptidase B1
chr12_-_56488153 1.08 ENST00000311966.9
glutaminase 2
chr17_-_38749806 1.07 ENST00000616199.4
polycomb group ring finger 2
chr1_+_156114700 1.07 ENST00000677389.1
ENST00000368300.9
ENST00000368299.7
lamin A/C
chr17_+_28744002 1.05 ENST00000618771.1
ENST00000262395.10
ENST00000422344.5
TNF receptor associated factor 4
chr11_-_72781833 1.05 ENST00000535054.1
ENST00000545082.5
StAR related lipid transfer domain containing 10
chr18_+_22169580 1.05 ENST00000269216.10
GATA binding protein 6
chr9_-_127873462 1.04 ENST00000223836.10
adenylate kinase 1
chr2_+_127423265 1.04 ENST00000402125.2
protein C, inactivator of coagulation factors Va and VIIIa
chr5_+_132369691 1.04 ENST00000245407.8
solute carrier family 22 member 5
chr1_+_155127866 1.03 ENST00000368406.2
ENST00000368407.8
ephrin A1
chr11_-_32435529 1.01 ENST00000448076.9
ENST00000452863.10
WT1 transcription factor
chr10_-_50885619 1.01 ENST00000373997.8
APOBEC1 complementation factor
chr11_-_34511710 1.00 ENST00000620316.4
ENST00000312319.6
E74 like ETS transcription factor 5
chr1_-_42740140 1.00 ENST00000372539.3
ENST00000296387.6
ENST00000539749.5
claudin 19
chr8_+_96493803 1.00 ENST00000518385.5
ENST00000302190.9
syndecan 2
chr16_+_2026834 0.99 ENST00000424542.7
ENST00000432365.6
SLC9A3 regulator 2
chr1_+_153778178 0.98 ENST00000532853.5
solute carrier family 27 member 3
chr17_+_7307602 0.97 ENST00000573542.5
ENST00000336458.13
eukaryotic translation initiation factor 5A
chr19_+_6740878 0.95 ENST00000596673.1
thyroid hormone receptor interactor 10
chr17_+_7307531 0.95 ENST00000576930.5
eukaryotic translation initiation factor 5A
chr12_+_53985783 0.94 ENST00000513209.1
novel protein, readthrough between HOXC10 and HOXC5
chr7_-_117873420 0.93 ENST00000160373.8
cortactin binding protein 2
chr19_-_45768627 0.92 ENST00000560160.1
SIX homeobox 5
chr22_+_25111810 0.91 ENST00000637069.1
KIAA1671
chr17_+_42853265 0.91 ENST00000592999.5
amine oxidase copper containing 3
chr17_+_7307579 0.91 ENST00000572815.5
eukaryotic translation initiation factor 5A
chr4_+_77605807 0.90 ENST00000682537.1
C-X-C motif chemokine ligand 13
chrX_-_100731504 0.89 ENST00000372989.5
ENST00000276141.10
synaptotagmin like 4
chr20_+_36154630 0.89 ENST00000338074.7
ENST00000636016.2
ENST00000373945.5
erythrocyte membrane protein band 4.1 like 1
chr12_-_56488125 0.88 ENST00000461077.1
glutaminase 2
chr14_-_22926413 0.88 ENST00000556043.5
protein arginine methyltransferase 5
chr4_+_71339014 0.86 ENST00000340595.4
solute carrier family 4 member 4
chr1_-_153628180 0.85 ENST00000339556.8
ENST00000440685.7
S100 calcium binding protein A13
chr2_-_219543537 0.85 ENST00000373891.2
chondroitin polymerizing factor
chr11_+_66593194 0.85 ENST00000310190.8
copper chaperone for superoxide dismutase
chr9_+_128322816 0.84 ENST00000300452.8
ENST00000372875.3
coenzyme Q4
chr7_-_27662836 0.83 ENST00000265395.7
3-hydroxyisobutyrate dehydrogenase
chr16_-_70685791 0.83 ENST00000616026.4
MTSS I-BAR domain containing 2
chr1_+_226548747 0.81 ENST00000366788.8
ENST00000366789.5
stum, mechanosensory transduction mediator homolog
chr8_-_6563409 0.81 ENST00000325203.9
angiopoietin 2
chr9_+_97501622 0.80 ENST00000259365.9
tropomodulin 1
chr22_+_31093358 0.80 ENST00000404574.5
smoothelin
chr1_-_153613095 0.80 ENST00000368706.9
S100 calcium binding protein A16
chr22_-_23767876 0.80 ENST00000520222.1
ENST00000401675.7
ENST00000484558.3
coiled-coil-helix-coiled-coil-helix domain containing 10
chrX_+_23664251 0.79 ENST00000379349.5
peroxiredoxin 4
chr16_+_28863946 0.78 ENST00000395532.8
SH2B adaptor protein 1
chr2_-_109614143 0.78 ENST00000356688.8
septin 10
chr19_-_45769204 0.77 ENST00000317578.7
SIX homeobox 5
chr6_-_43053832 0.76 ENST00000265348.9
ENST00000674134.1
ENST00000674100.1
cullin 7
chr11_-_32435360 0.75 ENST00000639563.3
WT1 transcription factor
chr2_-_219543793 0.75 ENST00000243776.11
chondroitin polymerizing factor
chrX_-_130165825 0.74 ENST00000675240.1
ENST00000319908.8
ENST00000674546.1
ENST00000287295.8
apoptosis inducing factor mitochondria associated 1
chr19_+_10701431 0.74 ENST00000250237.10
ENST00000592254.1
queuine tRNA-ribosyltransferase catalytic subunit 1
chr8_-_6563238 0.74 ENST00000629816.3
ENST00000523120.2
angiopoietin 2
chrX_-_130165699 0.73 ENST00000676328.1
ENST00000675857.1
ENST00000675427.1
ENST00000675092.1
apoptosis inducing factor mitochondria associated 1
chrX_-_130165873 0.73 ENST00000676229.1
apoptosis inducing factor mitochondria associated 1
chr3_-_190120881 0.72 ENST00000319332.10
prolyl 3-hydroxylase 2
chr3_+_49021071 0.72 ENST00000395458.6
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr11_+_66593171 0.71 ENST00000533244.6
copper chaperone for superoxide dismutase
chr14_+_73950252 0.71 ENST00000629426.2
coenzyme Q6, monooxygenase
chr7_+_43926419 0.71 ENST00000222402.8
ENST00000446008.5
ubiquitin conjugating enzyme E2 D4 (putative)
chr16_-_19886133 0.71 ENST00000568214.1
ENST00000569479.5
G protein-coupled receptor class C group 5 member B
chr9_-_128322407 0.70 ENST00000372890.6
TruB pseudouridine synthase family member 2
chr6_+_33200820 0.70 ENST00000374675.7
solute carrier family 39 member 7
chr17_-_7294592 0.69 ENST00000007699.10
Y-box binding protein 2
chr12_-_120469571 0.69 ENST00000550458.1
serine and arginine rich splicing factor 9
chr8_+_22165358 0.69 ENST00000306349.13
ENST00000306385.10
bone morphogenetic protein 1
chr2_+_178194460 0.69 ENST00000392505.6
ENST00000359685.7
ENST00000357080.8
ENST00000190611.9
ENST00000409045.7
oxysterol binding protein like 6
chr1_-_201112420 0.69 ENST00000362061.4
ENST00000681874.1
calcium voltage-gated channel subunit alpha1 S
chr9_+_34652167 0.68 ENST00000441545.7
ENST00000553620.5
interleukin 11 receptor subunit alpha
chr1_+_56645299 0.68 ENST00000371244.9
ENST00000610361.1
protein kinase AMP-activated catalytic subunit alpha 2
chr12_+_49972837 0.68 ENST00000618286.1
ENST00000315520.10
aquaporin 6
chrX_-_135022473 0.68 ENST00000391440.3
retrotransposon Gag like 8B
chr5_+_129904458 0.68 ENST00000305031.5
chondroitin sulfate synthase 3
chr22_-_31346317 0.67 ENST00000266269.10
POZ/BTB and AT hook containing zinc finger 1
chr15_+_34102037 0.67 ENST00000397766.4
piggyBac transposable element derived 4
chrX_-_85379659 0.66 ENST00000262753.9
POF1B actin binding protein
chr12_+_118136086 0.66 ENST00000261313.3
phosphatidylethanolamine binding protein 1
chr5_-_140043069 0.65 ENST00000289409.8
ENST00000358522.7
ENST00000289422.11
ENST00000541337.5
ENST00000361474.6
neuregulin 2
chr11_-_57322300 0.65 ENST00000527207.1
tankyrase 1 binding protein 1
chr5_+_138465472 0.65 ENST00000239938.5
early growth response 1
chr2_-_21043941 0.65 ENST00000399256.4
apolipoprotein B
chr15_-_89496574 0.65 ENST00000268122.9
Rh family C glycoprotein
chr12_+_80937815 0.64 ENST00000549175.1
acyl-CoA synthetase short chain family member 3
chr1_+_15756659 0.64 ENST00000375771.5
filamin binding LIM protein 1
chr12_+_80707625 0.64 ENST00000228641.4
myogenic factor 6
chr1_+_153628393 0.64 ENST00000368696.3
ENST00000292169.6
ENST00000436839.1
S100 calcium binding protein A1
chr4_+_127782270 0.64 ENST00000508549.5
ENST00000296464.9
heat shock protein family A (Hsp70) member 4 like
chr19_-_5785619 0.64 ENST00000586012.1
ENST00000590343.1
novel protein
dihydrouridine synthase 3 like
chr1_-_159862648 0.63 ENST00000368100.1
V-set and immunoglobulin domain containing 8
chr1_-_201112451 0.63 ENST00000367338.7
calcium voltage-gated channel subunit alpha1 S
chr5_-_124744513 0.63 ENST00000504926.5
zinc finger protein 608
chr12_+_101568350 0.62 ENST00000550514.5
myosin binding protein C1
chr4_+_3441960 0.62 ENST00000382774.8
ENST00000511533.1
HGF activator
chr2_+_9961165 0.61 ENST00000405379.6
grainyhead like transcription factor 1
chr9_+_121743561 0.61 ENST00000648693.1
DAB2 interacting protein
chr2_-_96843992 0.61 ENST00000418232.5
ankyrin repeat domain 23
chr1_-_111989608 0.61 ENST00000302127.5
potassium voltage-gated channel subfamily D member 3
chr2_-_38377256 0.61 ENST00000443098.5
ENST00000449130.5
ENST00000651368.1
ENST00000378954.9
ENST00000419554.6
ENST00000451483.1
ENST00000406122.5
atlastin GTPase 2
chrX_-_130165664 0.61 ENST00000535724.6
ENST00000346424.6
ENST00000676436.1
apoptosis inducing factor mitochondria associated 1
chr17_-_8630749 0.61 ENST00000379980.8
ENST00000269243.8
myosin heavy chain 10
chr20_-_17659917 0.60 ENST00000610403.4
ribosome binding protein 1
chr16_+_28863812 0.60 ENST00000684370.1
SH2B adaptor protein 1
chr2_-_96844012 0.60 ENST00000318357.9
ENST00000331001.2
ankyrin repeat domain 23
chr12_+_27524151 0.60 ENST00000545334.5
ENST00000540114.5
ENST00000537927.5
ENST00000228425.11
ENST00000318304.12
ENST00000535047.5
ENST00000542629.5
PPFIA binding protein 1
chr7_+_66087761 0.60 ENST00000450043.2
novel protein
chr11_-_119340816 0.60 ENST00000528368.3
C1q and TNF related 5
chr8_+_22165140 0.60 ENST00000397814.7
ENST00000354870.5
bone morphogenetic protein 1
chr6_+_52671080 0.59 ENST00000211314.5
transmembrane protein 14A
chr12_+_72272360 0.59 ENST00000547300.2
ENST00000261180.10
thyrotropin releasing hormone degrading enzyme
chr17_+_4950147 0.58 ENST00000522301.5
enolase 3
chr20_-_35699298 0.58 ENST00000306750.3
NFS1 cysteine desulfurase
chr1_+_6785518 0.58 ENST00000467404.6
calmodulin binding transcription activator 1
chr8_+_116938180 0.58 ENST00000378279.4
alanine and arginine rich domain containing protein
chr14_+_73950489 0.58 ENST00000554320.1
coenzyme Q6, monooxygenase
chr14_+_24368020 0.58 ENST00000554050.5
ENST00000554903.1
ENST00000250373.9
ENST00000554779.1
ENST00000553708.5
nuclear factor of activated T cells 4
chr6_+_33200860 0.57 ENST00000374677.8
solute carrier family 39 member 7
chr17_-_82840010 0.57 ENST00000269394.4
ENST00000572562.1
zinc finger protein 750
chr1_-_22143088 0.57 ENST00000290167.11
Wnt family member 4
chr10_+_49942048 0.57 ENST00000651259.3
ENST00000652716.1
translocase of inner mitochondrial membrane 23 homolog B
chr10_-_75401746 0.56 ENST00000372524.5
zinc finger protein 503
chr9_-_34589701 0.56 ENST00000351266.8
ciliary neurotrophic factor receptor
chr12_+_120302316 0.56 ENST00000536460.1
ENST00000202967.4
sirtuin 4
chr17_-_28357455 0.56 ENST00000618887.2
ENST00000540200.6
DNA polymerase delta interacting protein 2
chr10_+_23694707 0.55 ENST00000376462.5
KIAA1217
chr22_-_43343283 0.55 ENST00000615096.4
ENST00000290460.7
ENST00000360835.9
signal peptide, CUB domain and EGF like domain containing 1
chrX_-_84188148 0.55 ENST00000262752.5
ribosomal protein S6 kinase A6
chr9_-_34590123 0.55 ENST00000417345.2
ENST00000610543.4
ciliary neurotrophic factor receptor
chr17_+_7404851 0.55 ENST00000575301.5
neuroligin 2
chr6_+_19837362 0.54 ENST00000378700.8
inhibitor of DNA binding 4, HLH protein
chr1_+_109249530 0.54 ENST00000271332.4
cadherin EGF LAG seven-pass G-type receptor 2
chr14_+_85530127 0.54 ENST00000330753.6
fibronectin leucine rich transmembrane protein 2
chr21_-_43060546 0.54 ENST00000430013.1
cystathionine beta-synthase
chr9_-_34589716 0.54 ENST00000378980.8
ciliary neurotrophic factor receptor
chr4_+_102501298 0.54 ENST00000394820.8
ENST00000226574.9
ENST00000511926.5
ENST00000507079.5
nuclear factor kappa B subunit 1
chr20_-_35699317 0.54 ENST00000397425.5
ENST00000374092.9
ENST00000541387.5
NFS1 cysteine desulfurase
chr16_-_31508370 0.53 ENST00000430477.6
ENST00000567994.5
ENST00000570164.5
ENST00000327237.7
RUS family member 1
chrX_+_153781033 0.53 ENST00000370104.5
ENST00000370108.7
ENST00000370101.8
ENST00000430541.5
ENST00000370100.5
SRSF protein kinase 3
chr15_-_34101807 0.53 ENST00000527822.5
ENST00000528949.1
ENST00000256545.9
ER membrane protein complex subunit 7
chr6_+_133241318 0.53 ENST00000430974.6
ENST00000355286.12
ENST00000355167.8
ENST00000431403.3
EYA transcriptional coactivator and phosphatase 4

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.9 2.8 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.8 2.3 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.7 2.2 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.7 6.4 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.7 2.8 GO:1904045 cellular response to aldosterone(GO:1904045)
0.7 2.0 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.6 2.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.6 2.9 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.5 2.4 GO:0072301 regulation of metanephric glomerular mesangial cell proliferation(GO:0072301)
0.4 3.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.4 4.0 GO:0051552 flavone metabolic process(GO:0051552)
0.4 1.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 1.7 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.4 1.2 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.4 2.3 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.4 3.3 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.3 0.9 GO:0035565 regulation of pronephros size(GO:0035565)
0.3 2.7 GO:0006642 triglyceride mobilization(GO:0006642)
0.3 1.5 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.3 0.9 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.3 2.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.3 0.6 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 1.1 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.3 1.0 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.3 1.6 GO:0015680 intracellular copper ion transport(GO:0015680)
0.3 1.0 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.3 1.0 GO:0014028 notochord formation(GO:0014028)
0.3 3.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 3.7 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.2 1.7 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.2 4.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 0.7 GO:0009386 translational attenuation(GO:0009386)
0.2 2.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 0.6 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.2 1.4 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.2 0.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 0.6 GO:2000224 renal vesicle induction(GO:0072034) positive regulation of steroid hormone biosynthetic process(GO:0090031) regulation of testosterone biosynthetic process(GO:2000224)
0.2 3.3 GO:0044849 estrous cycle(GO:0044849)
0.2 1.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.2 0.7 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.2 0.5 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.2 1.0 GO:0008218 bioluminescence(GO:0008218)
0.2 3.0 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 2.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.2 0.2 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 2.9 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.4 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 3.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 2.0 GO:0003360 brainstem development(GO:0003360)
0.1 0.6 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.8 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.4 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.1 0.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.8 GO:2000984 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.1 2.2 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.5 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 2.5 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 1.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 1.0 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.5 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 0.9 GO:0060161 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.1 0.3 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1 0.4 GO:0018277 protein deamination(GO:0018277)
0.1 3.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.4 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.1 1.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.1 1.2 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.1 1.6 GO:0007512 adult heart development(GO:0007512)
0.1 0.5 GO:0009093 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.1 0.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.4 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.3 GO:0006463 steroid hormone receptor complex assembly(GO:0006463)
0.1 0.3 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 1.3 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.1 0.5 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.9 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.1 0.5 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.1 0.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.6 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 1.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.3 GO:0071110 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
0.1 0.7 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 1.3 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.1 0.3 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 1.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.2 GO:0048561 establishment of organ orientation(GO:0048561)
0.1 0.7 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.7 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.8 GO:0051715 replicative cell aging(GO:0001302) cytolysis in other organism(GO:0051715)
0.1 0.4 GO:0048664 neuron fate determination(GO:0048664)
0.1 1.6 GO:0034030 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.1 0.2 GO:0072287 distal tubule morphogenesis(GO:0072156) metanephric distal tubule morphogenesis(GO:0072287)
0.1 1.6 GO:0001502 cartilage condensation(GO:0001502)
0.1 0.6 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.6 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.7 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.1 0.2 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.2 GO:0090410 malonate catabolic process(GO:0090410)
0.0 0.3 GO:0000432 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.0 1.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:1904847 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.6 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.5 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.8 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 2.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 2.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 1.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.6 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.5 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.3 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 1.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.3 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 2.9 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999)
0.0 0.6 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.4 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.6 GO:0002934 desmosome organization(GO:0002934)
0.0 0.4 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.3 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.7 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 1.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.7 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.3 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.1 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.4 GO:0010225 response to UV-C(GO:0010225)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.6 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.0 0.3 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.6 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.7 GO:0006833 water transport(GO:0006833)
0.0 0.1 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 1.5 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.5 GO:0072189 ureter development(GO:0072189)
0.0 0.3 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 1.3 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 1.2 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.6 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.0 GO:1904640 response to methionine(GO:1904640)
0.0 1.3 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.6 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.7 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.1 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 1.0 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 1.2 GO:0070206 protein trimerization(GO:0070206)
0.0 1.5 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0015824 proline transport(GO:0015824)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 1.0 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.4 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 2.0 GO:0048706 embryonic skeletal system development(GO:0048706)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.5 3.5 GO:1990393 3M complex(GO:1990393)
0.4 1.7 GO:0005588 collagen type V trimer(GO:0005588)
0.3 2.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 1.5 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.3 6.4 GO:0043203 axon hillock(GO:0043203)
0.2 3.7 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 2.8 GO:0032009 early phagosome(GO:0032009)
0.2 3.3 GO:0005642 annulate lamellae(GO:0005642)
0.2 1.4 GO:0001739 sex chromatin(GO:0001739)
0.1 1.0 GO:0097513 myosin II filament(GO:0097513)
0.1 2.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.6 GO:1990032 parallel fiber(GO:1990032)
0.1 1.1 GO:0005638 lamin filament(GO:0005638)
0.1 0.8 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.9 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 1.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 2.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 2.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.7 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 3.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 1.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.9 GO:0034709 methylosome(GO:0034709)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0002133 polycystin complex(GO:0002133)
0.0 1.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:1990696 stereocilia ankle link(GO:0002141) USH2 complex(GO:1990696)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0071953 elastic fiber(GO:0071953)
0.0 0.3 GO:0044326 dendritic spine neck(GO:0044326)
0.0 1.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 3.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 3.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.0 7.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 2.8 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 3.2 GO:0005604 basement membrane(GO:0005604)
0.0 1.0 GO:0031941 filamentous actin(GO:0031941)
0.0 12.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.0 GO:0030118 clathrin coat(GO:0030118)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 3.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.5 2.9 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.5 2.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.5 2.3 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.4 3.1 GO:0004359 glutaminase activity(GO:0004359)
0.4 1.1 GO:0031071 cysteine desulfurase activity(GO:0031071)
0.3 2.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.3 2.7 GO:0035473 lipase binding(GO:0035473)
0.3 1.6 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.3 2.2 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.3 1.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.2 3.1 GO:0050692 DBD domain binding(GO:0050692)
0.2 1.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 2.1 GO:0043237 laminin-1 binding(GO:0043237)
0.2 0.7 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.2 2.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 2.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 1.5 GO:0051373 FATZ binding(GO:0051373)
0.2 0.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 3.0 GO:0004985 opioid receptor activity(GO:0004985)
0.2 0.8 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 0.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 3.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 1.7 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.7 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.6 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.4 GO:0047012 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
0.1 1.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.9 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.5 GO:0050421 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.1 0.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.5 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.4 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.6 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 3.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.8 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 4.0 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.8 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 2.4 GO:0071949 FAD binding(GO:0071949)
0.1 0.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.4 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.3 GO:0004080 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.1 2.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 2.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.6 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.3 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 2.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.9 GO:0043394 proteoglycan binding(GO:0043394)
0.1 0.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.8 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.3 GO:0031432 titin binding(GO:0031432)
0.1 0.4 GO:0045545 syndecan binding(GO:0045545)
0.1 0.3 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.2 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 1.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 5.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.4 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 2.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 6.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.7 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.9 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0015250 water channel activity(GO:0015250)
0.0 1.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 10.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 2.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.6 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 2.6 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0042805 actinin binding(GO:0042805)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 4.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 8.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.4 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 ST ADRENERGIC Adrenergic Pathway
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 2.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 4.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 4.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 4.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 2.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.9 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 2.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 2.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 2.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 2.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 3.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 2.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.8 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 2.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)