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Illumina Body Map 2 (GSE30611)

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Results for LHX2

Z-value: 0.68

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Transcription factors associated with LHX2

Gene Symbol Gene ID Gene Info
ENSG00000106689.11 LIM homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX2hg38_v1_chr9_+_124011738_1240117770.106.0e-01Click!

Activity profile of LHX2 motif

Sorted Z-values of LHX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_81483226 1.77 ENST00000256104.5
fatty acid binding protein 4
chr7_+_80624961 1.23 ENST00000436384.5
CD36 molecule
chr2_-_174847765 1.22 ENST00000443238.6
chimerin 1
chr15_+_51377410 1.18 ENST00000612989.1
gliomedin
chr2_-_174847525 1.18 ENST00000295497.12
ENST00000652036.1
ENST00000444394.6
ENST00000650731.1
chimerin 1
chr15_-_72228676 1.13 ENST00000561609.5
pyruvate kinase M1/2
chr13_-_99307387 1.11 ENST00000376414.5
G protein-coupled receptor 183
chr5_+_36606355 1.03 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr14_+_51847145 0.98 ENST00000615906.4
G protein subunit gamma 2
chr18_+_58341038 0.95 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr4_-_89835617 0.95 ENST00000611107.1
ENST00000345009.8
ENST00000505199.5
ENST00000502987.5
synuclein alpha
chr7_-_22194709 0.93 ENST00000458533.5
Rap guanine nucleotide exchange factor 5
chr7_-_137343752 0.87 ENST00000393083.2
pleiotrophin
chr1_-_183590876 0.87 ENST00000367536.5
neutrophil cytosolic factor 2
chr1_+_99646025 0.85 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr7_-_137343688 0.83 ENST00000348225.7
pleiotrophin
chr6_-_75363003 0.81 ENST00000370020.1
filamin A interacting protein 1
chr14_-_33951052 0.80 ENST00000250457.9
ENST00000547327.2
egl-9 family hypoxia inducible factor 3
chr6_+_26199509 0.79 ENST00000356530.5
H2B clustered histone 7
chrX_+_100584928 0.76 ENST00000373031.5
tenomodulin
chr10_-_114632011 0.73 ENST00000651023.1
actin binding LIM protein 1
chr17_-_445939 0.73 ENST00000329099.4
refilin B
chr7_-_83649097 0.72 ENST00000643230.2
semaphorin 3E
chr1_-_115089414 0.71 ENST00000433172.3
ENST00000369515.6
ENST00000369516.7
tetraspanin 2
chr4_-_137532452 0.70 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr20_+_33283205 0.70 ENST00000253354.2
BPI fold containing family B member 1
chr1_+_86547070 0.69 ENST00000370563.3
chloride channel accessory 4
chr14_+_56117702 0.66 ENST00000559044.5
pellino E3 ubiquitin protein ligase family member 2
chr15_+_51377315 0.66 ENST00000558426.5
gliomedin
chr6_+_32844789 0.64 ENST00000414474.5
proteasome 20S subunit beta 9
chr16_+_31259922 0.64 ENST00000648685.1
ENST00000544665.9
integrin subunit alpha M
chr14_-_89412025 0.63 ENST00000553840.5
ENST00000556916.5
forkhead box N3
chr2_-_89177160 0.63 ENST00000484817.1
immunoglobulin kappa variable 2-24
chr1_+_92168915 0.63 ENST00000637221.2
BTB domain containing 8
chr13_-_19181773 0.62 ENST00000618094.1
ENST00000400113.8
tubulin alpha 3c
chrX_-_77634229 0.60 ENST00000675732.1
ATRX chromatin remodeler
chr18_+_68798065 0.60 ENST00000360242.9
coiled-coil domain containing 102B
chr6_-_130970428 0.59 ENST00000529208.5
erythrocyte membrane protein band 4.1 like 2
chr9_+_111896804 0.57 ENST00000374279.4
UDP-glucose ceramide glucosyltransferase
chr18_+_36544544 0.56 ENST00000591635.5
formin homology 2 domain containing 3
chr6_+_126340107 0.56 ENST00000368328.5
ENST00000368326.5
ENST00000368325.5
centromere protein W
chr14_-_106005574 0.55 ENST00000390595.3
immunoglobulin heavy variable 1-3
chr13_+_31945826 0.53 ENST00000647500.1
FRY microtubule binding protein
chr8_-_19602484 0.52 ENST00000454498.6
ENST00000520003.5
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr1_-_74634855 0.52 ENST00000420661.6
glutamate rich 3
chr10_-_114658268 0.51 ENST00000649363.1
ENST00000277895.9
actin binding LIM protein 1
chr10_-_13972355 0.50 ENST00000264546.10
FERM domain containing 4A
chr2_+_161624335 0.50 ENST00000375514.9
ENST00000415876.6
solute carrier family 4 member 10
chr7_-_14841267 0.49 ENST00000406247.7
ENST00000399322.7
diacylglycerol kinase beta
chr18_+_34976928 0.49 ENST00000591734.5
ENST00000413393.5
ENST00000589180.5
ENST00000587359.5
microtubule associated protein RP/EB family member 2
chr12_+_40742342 0.49 ENST00000548005.5
ENST00000552248.5
contactin 1
chr2_-_74392025 0.49 ENST00000440727.1
ENST00000409240.5
dynactin subunit 1
chr3_+_108822778 0.47 ENST00000295756.11
T cell receptor associated transmembrane adaptor 1
chr8_-_108248700 0.45 ENST00000220849.10
ENST00000678937.1
ENST00000678901.1
ENST00000678243.1
ENST00000677674.1
ENST00000521297.2
ENST00000677272.1
ENST00000522352.6
ENST00000678042.1
ENST00000519627.2
ENST00000521440.6
ENST00000678773.1
ENST00000676698.1
ENST00000518345.2
ENST00000677447.1
ENST00000676548.1
ENST00000519030.6
ENST00000518442.5
eukaryotic translation initiation factor 3 subunit E
chr2_-_55049184 0.45 ENST00000357376.7
reticulon 4
chr10_-_114526897 0.45 ENST00000428430.1
ENST00000392952.7
actin binding LIM protein 1
chr4_+_168497066 0.44 ENST00000261509.10
palladin, cytoskeletal associated protein
chr1_+_160739286 0.43 ENST00000359331.8
ENST00000495334.1
SLAM family member 7
chr18_-_36798482 0.42 ENST00000590258.2
tubulin polyglutamylase complex subunit 2
chr21_-_33641721 0.40 ENST00000399442.1
ENST00000413017.2
ENST00000445393.5
ENST00000417979.5
ENST00000381554.8
ENST00000426935.5
ENST00000381540.7
ENST00000361534.6
crystallin zeta like 1
chr12_+_40393392 0.39 ENST00000676020.1
mucin 19, oligomeric
chr14_+_22086401 0.39 ENST00000390451.2
T cell receptor alpha variable 23/delta variable 6
chr3_-_161105224 0.39 ENST00000651254.1
ENST00000651178.1
ENST00000476999.6
ENST00000652596.1
ENST00000651305.1
ENST00000652111.1
ENST00000651292.1
ENST00000651282.1
ENST00000651380.1
ENST00000494173.7
ENST00000484127.5
ENST00000650733.1
ENST00000494818.6
ENST00000492353.5
ENST00000652143.1
ENST00000473142.5
ENST00000651147.1
ENST00000468268.5
ENST00000460353.2
ENST00000651953.1
ENST00000651972.1
ENST00000652730.1
ENST00000651460.1
ENST00000652059.1
ENST00000651509.1
ENST00000651801.1
ENST00000651686.1
ENST00000320474.10
ENST00000392781.7
ENST00000392779.6
ENST00000651791.1
ENST00000651117.1
ENST00000652032.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr3_+_63443306 0.39 ENST00000472899.5
ENST00000479198.5
ENST00000460711.5
ENST00000465156.1
synaptoporin
chr10_-_29634964 0.38 ENST00000375398.6
ENST00000355867.8
supervillin
chr16_+_283157 0.38 ENST00000219406.11
ENST00000404312.5
ENST00000456379.1
protein disulfide isomerase family A member 2
chr18_+_3247778 0.37 ENST00000217652.8
ENST00000578611.5
ENST00000583449.1
myosin light chain 12A
chr17_-_31314066 0.37 ENST00000577894.1
ecotropic viral integration site 2B
chr1_+_160739265 0.37 ENST00000368042.7
SLAM family member 7
chr5_+_119333151 0.37 ENST00000513374.1
TNF alpha induced protein 8
chr16_-_15642488 0.37 ENST00000549219.1
meiosis regulator and mRNA stability factor 1
chr4_+_69931066 0.36 ENST00000246891.9
casein alpha s1
chr7_-_38265678 0.36 ENST00000443402.6
T cell receptor gamma constant 1
chr15_+_53978410 0.35 ENST00000260323.16
unc-13 homolog C
chr20_+_5750381 0.34 ENST00000378979.8
ENST00000303142.11
shieldin complex subunit 1
chr11_-_62556230 0.34 ENST00000530285.5
AHNAK nucleoprotein
chr11_+_64234569 0.34 ENST00000309422.7
ENST00000426086.3
vascular endothelial growth factor B
chr6_-_26199272 0.33 ENST00000650491.1
ENST00000635200.1
ENST00000341023.2
novel protein
H2A clustered histone 7
chr14_+_23376786 0.33 ENST00000359320.7
CKLF like MARVEL transmembrane domain containing 5
chr1_+_160739239 0.32 ENST00000368043.8
SLAM family member 7
chr2_+_68734773 0.32 ENST00000409202.8
Rho GTPase activating protein 25
chr7_-_38300288 0.32 ENST00000390341.2
T cell receptor gamma variable 10 (non-functional)
chr15_-_59689283 0.32 ENST00000607373.6
ENST00000612191.4
ENST00000267859.8
BCL2 interacting protein 2
chr2_-_230219944 0.32 ENST00000455674.2
ENST00000392048.7
ENST00000258381.11
ENST00000358662.9
ENST00000258382.10
SP110 nuclear body protein
chr3_+_108822759 0.32 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chr18_+_63702958 0.32 ENST00000544088.6
serpin family B member 11
chr2_+_68734861 0.31 ENST00000467265.5
Rho GTPase activating protein 25
chr3_+_172754457 0.31 ENST00000441497.6
epithelial cell transforming 2
chr15_+_53978201 0.31 ENST00000647821.1
unc-13 homolog C
chr13_-_99258366 0.31 ENST00000397470.5
ENST00000397473.7
G protein-coupled receptor 18
chr5_-_151093566 0.30 ENST00000521001.1
TNFAIP3 interacting protein 1
chr7_+_101817601 0.30 ENST00000292535.12
ENST00000546411.7
ENST00000549414.6
ENST00000550008.6
ENST00000556210.1
cut like homeobox 1
chr15_-_72271244 0.30 ENST00000287196.13
poly(ADP-ribose) polymerase family member 6
chr6_+_112087576 0.30 ENST00000368656.7
ENST00000604268.1
family with sequence similarity 229 member B
chr12_-_91179517 0.30 ENST00000551354.1
decorin
chr10_-_88952763 0.29 ENST00000224784.10
actin alpha 2, smooth muscle
chr5_+_141223332 0.29 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
protocadherin beta 14
novel protein
chr13_+_77741393 0.29 ENST00000496045.5
SLAIN motif family member 1
chrX_+_18707638 0.28 ENST00000472826.5
ENST00000496075.2
protein phosphatase with EF-hand domain 1
chr2_+_172821575 0.28 ENST00000397087.7
Rap guanine nucleotide exchange factor 4
chr11_-_40294089 0.28 ENST00000278198.2
leucine rich repeat containing 4C
chr7_+_142313144 0.27 ENST00000390357.3
T cell receptor beta variable 4-1
chr12_+_48328980 0.27 ENST00000335017.1
H1.7 linker histone
chr1_-_89126066 0.27 ENST00000370466.4
guanylate binding protein 2
chr10_+_122560639 0.26 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
deleted in malignant brain tumors 1
chr12_-_91179472 0.26 ENST00000550099.5
ENST00000546391.5
decorin
chr7_-_83648547 0.25 ENST00000642232.1
semaphorin 3E
chr13_+_24309565 0.25 ENST00000332018.4
C1q and TNF related 9
chr10_+_93566659 0.25 ENST00000371481.9
ENST00000371483.8
ENST00000604414.1
free fatty acid receptor 4
chr11_+_24497155 0.24 ENST00000529015.5
ENST00000533227.5
leucine zipper protein 2
chr16_+_86566821 0.24 ENST00000649859.1
forkhead box C2
chr11_+_24496988 0.24 ENST00000336930.11
leucine zipper protein 2
chr1_-_153922742 0.23 ENST00000634408.1
ENST00000634791.1
GATA zinc finger domain containing 2B
chr13_+_24270841 0.22 ENST00000454083.1
spermatogenesis associated 13
chr5_+_141177790 0.22 ENST00000239444.4
ENST00000623995.1
protocadherin beta 8
novel transcript
chr3_-_20012250 0.22 ENST00000389050.5
protein phosphatase 2C like domain containing 1
chr11_-_108222594 0.22 ENST00000278612.9
nuclear protein, coactivator of histone transcription
chr20_+_5750437 0.21 ENST00000445603.1
ENST00000442185.1
shieldin complex subunit 1
chr3_+_4680617 0.21 ENST00000648212.1
inositol 1,4,5-trisphosphate receptor type 1
chr7_+_20647343 0.21 ENST00000443026.6
ENST00000406935.5
ATP binding cassette subfamily B member 5
chr2_-_230219902 0.21 ENST00000409815.6
SP110 nuclear body protein
chr13_+_77741331 0.20 ENST00000462234.5
SLAIN motif family member 1
chr17_-_38853629 0.20 ENST00000378096.3
ENST00000479035.7
ENST00000394332.5
ENST00000394333.5
ENST00000577407.5
ribosomal protein L23
chr13_+_24270713 0.20 ENST00000409126.5
spermatogenesis associated 13
chr17_+_59940908 0.20 ENST00000591035.1
novel protein
chr18_-_5521373 0.20 ENST00000580989.5
erythrocyte membrane protein band 4.1 like 3
chr4_-_46388713 0.20 ENST00000507069.5
gamma-aminobutyric acid type A receptor subunit alpha2
chr10_-_14330879 0.20 ENST00000357447.7
FERM domain containing 4A
chr2_+_108588453 0.19 ENST00000393310.5
LIM zinc finger domain containing 1
chr16_-_48610150 0.19 ENST00000262384.4
NEDD4 binding protein 1
chr1_-_246193727 0.19 ENST00000391836.3
SET and MYND domain containing 3
chr15_-_42272825 0.19 ENST00000566474.5
transmembrane protein 87A
chr12_-_48852133 0.18 ENST00000552512.5
ENST00000551468.1
DEAD-box helicase 23
chr10_+_122560751 0.18 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
deleted in malignant brain tumors 1
chr12_-_118359105 0.18 ENST00000541186.5
ENST00000539872.5
TAO kinase 3
chr12_-_118359639 0.18 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAO kinase 3
chr2_-_88857582 0.18 ENST00000390237.2
immunoglobulin kappa constant
chr12_-_118359166 0.18 ENST00000542902.5
TAO kinase 3
chr4_+_15469865 0.17 ENST00000515124.6
ENST00000512702.6
ENST00000503292.6
ENST00000424120.6
ENST00000507954.5
ENST00000514450.3
ENST00000503658.2
coiled-coil and C2 domain containing 2A
chr1_-_150765785 0.17 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
cathepsin S
chr3_+_35680994 0.16 ENST00000441454.5
cAMP regulated phosphoprotein 21
chr15_+_21579912 0.15 ENST00000628444.1
long intergenic non-protein coding RNA 2203
chr3_+_73061659 0.15 ENST00000533473.1
endogenous Bornavirus like nucleoprotein 2
chr21_+_33642476 0.15 ENST00000381291.8
ENST00000381285.8
ENST00000399367.7
ENST00000399352.5
ENST00000399355.6
ENST00000399349.5
ENST00000381318.8
intersectin 1
chr8_+_22567038 0.14 ENST00000523348.1
sorbin and SH3 domain containing 3
chr7_-_5959083 0.14 ENST00000539903.5
radial spoke head 10 homolog B
chr21_+_33642400 0.13 ENST00000399353.5
ENST00000444491.5
intersectin 1
chr1_-_113871665 0.13 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
protein tyrosine phosphatase non-receptor type 22
chr3_-_69080350 0.13 ENST00000630585.1
ENST00000361055.9
ENST00000415609.6
ENST00000349511.8
ubiquitin like modifier activating enzyme 3
chr2_+_28778848 0.13 ENST00000418910.1
protein phosphatase 1 catalytic subunit beta
chr14_+_51847116 0.13 ENST00000553560.5
G protein subunit gamma 2
chr5_-_157109025 0.13 ENST00000307851.9
hepatitis A virus cellular receptor 2
chr1_+_192716132 0.13 ENST00000647225.1
ENST00000443181.2
ribosomal protein S27a pseudogene 5
chr2_-_197676012 0.13 ENST00000429081.1
raftlin family member 2
chr7_-_81770122 0.12 ENST00000423064.7
hepatocyte growth factor
chr9_+_102995308 0.12 ENST00000612124.4
ENST00000374798.8
ENST00000487798.5
cylicin 2
chr7_-_100119323 0.12 ENST00000523306.5
ENST00000344095.8
ENST00000417349.5
ENST00000493322.5
ENST00000520135.5
ENST00000460673.2
ENST00000453269.7
ENST00000452041.5
ENST00000452438.6
ENST00000451699.5
TATA-box binding protein associated factor 6
chr3_-_161105070 0.12 ENST00000651430.1
ENST00000650695.1
ENST00000651689.1
ENST00000651916.1
ENST00000488170.5
ENST00000652377.1
ENST00000652669.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr5_-_157109115 0.12 ENST00000522593.5
hepatitis A virus cellular receptor 2
chr13_+_76948500 0.12 ENST00000377462.6
aconitate decarboxylase 1
chr17_+_50746614 0.12 ENST00000513969.5
ENST00000503728.1
LUC7 like 3 pre-mRNA splicing factor
chr2_+_102355750 0.11 ENST00000233957.7
interleukin 18 receptor 1
chr14_+_22163226 0.11 ENST00000390458.3
T cell receptor alpha variable 29/delta variable 5
chr16_+_69311339 0.11 ENST00000254950.13
vacuolar protein sorting 4 homolog A
chr16_+_23641452 0.11 ENST00000300087.7
ENST00000563998.5
dynactin subunit 5
chr14_-_80959484 0.10 ENST00000555529.5
ENST00000556042.5
ENST00000556981.5
centrosomal protein 128
chr1_-_205121964 0.10 ENST00000264515.11
RB binding protein 5, histone lysine methyltransferase complex subunit
chr2_-_127526444 0.10 ENST00000295321.9
interacts with SUPT6H, CTD assembly factor 1
chr7_+_20647388 0.10 ENST00000258738.10
ATP binding cassette subfamily B member 5
chr16_-_18876305 0.10 ENST00000563235.5
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr10_+_70404129 0.10 ENST00000373218.5
eukaryotic translation initiation factor 4E binding protein 2
chr10_+_116427839 0.10 ENST00000369230.4
pancreatic lipase related protein 3
chr1_+_70221396 0.09 ENST00000395136.6
serine and arginine rich splicing factor 11
chr11_+_124256376 0.09 ENST00000641992.2
olfactory receptor family 8 subfamily G member 5
chr17_-_4802322 0.09 ENST00000635921.1
chromosome 17 open reading frame 114
chr1_-_7940825 0.09 ENST00000377507.8
TNF receptor superfamily member 9
chr12_-_123272234 0.09 ENST00000544658.5
cyclin dependent kinase 2 associated protein 1
chr12_-_25195074 0.09 ENST00000354189.9
ENST00000676236.1
ENST00000545133.5
ENST00000554347.1
ENST00000674567.1
ENST00000395987.8
ENST00000320267.13
ENST00000395990.6
cilia and flagella associated protein 94
chr16_-_56451316 0.09 ENST00000300291.10
nudix hydrolase 21
chr11_-_124399024 0.08 ENST00000641139.1
olfactory receptor family 8 subfamily B member 3
chr3_+_35681352 0.08 ENST00000436702.5
ENST00000438071.1
cAMP regulated phosphoprotein 21
chr19_-_53129659 0.08 ENST00000601215.5
zinc finger protein 415
chr5_-_134367144 0.08 ENST00000265334.9
cyclin dependent kinase like 3
chr7_-_81770362 0.08 ENST00000412881.5
hepatocyte growth factor
chr2_-_55010348 0.08 ENST00000394609.6
reticulon 4
chr17_-_7857139 0.07 ENST00000576384.1
N-alpha-acetyltransferase 38, NatC auxiliary subunit
chr10_-_60141004 0.07 ENST00000355288.6
ankyrin 3
chr1_+_152811971 0.07 ENST00000360090.4
late cornified envelope 1B
chr3_+_35680932 0.07 ENST00000396481.6
cAMP regulated phosphoprotein 21
chr14_+_22096017 0.06 ENST00000390452.2
T cell receptor delta variable 1
chr1_-_207032749 0.06 ENST00000359470.6
ENST00000461135.2
chromosome 1 open reading frame 116
chr11_-_56748696 0.06 ENST00000641581.1
ENST00000641668.1
olfactory receptor family 9 subfamily G member 4
chr3_+_98147479 0.06 ENST00000641380.1
olfactory receptor family 5 subfamily H member 14
chr1_-_153922901 0.06 ENST00000634401.1
ENST00000368655.5
GATA zinc finger domain containing 2B
chr13_-_46378510 0.06 ENST00000439642.1
rubicon like autophagy enhancer
chr4_+_37960397 0.06 ENST00000504686.2
pituitary tumor-transforming 2
chr3_+_119468952 0.06 ENST00000476573.5
ENST00000295588.9
protein O-glucosyltransferase 1
chr5_-_35938572 0.06 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
calcyphosine like
chr11_+_63838902 0.05 ENST00000377810.8
microtubule affinity regulating kinase 2
chr6_+_54018910 0.05 ENST00000514921.5
ENST00000274897.9
ENST00000370877.6
muscular LMNA interacting protein

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.2 0.7 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.2 0.6 GO:0099404 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.2 0.6 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.2 0.9 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.7 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 0.8 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 1.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.5 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.3 GO:0048058 compound eye corneal lens development(GO:0048058)
0.1 0.3 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.8 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 1.2 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 1.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.5 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.1 1.8 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.5 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 1.0 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 1.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.2 GO:1901257 negative regulation of interleukin-3 production(GO:0032712) negative regulation of granulocyte colony-stimulating factor production(GO:0071656) negative regulation of macrophage colony-stimulating factor production(GO:1901257)
0.1 0.3 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.2 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.2 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.5 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.8 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 2.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.6 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.5 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 1.1 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 1.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.5 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 1.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.6 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.6 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.0 0.9 GO:0045730 respiratory burst(GO:0045730)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 2.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 1.1 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.6 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.5 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.6 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.9 GO:0032010 phagolysosome(GO:0032010)
0.1 0.7 GO:0044305 calyx of Held(GO:0044305)
0.0 0.3 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.6 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.6 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.8 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 2.4 GO:0032432 actin filament bundle(GO:0032432)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.8 GO:0005811 lipid particle(GO:0005811)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.9 GO:0005771 multivesicular body(GO:0005771)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 0.6 GO:0015616 DNA translocase activity(GO:0015616)
0.2 1.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 0.9 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.4 GO:0035375 zymogen binding(GO:0035375)
0.1 0.5 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.5 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 1.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.1 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 1.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.4 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.6 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.6 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.0 0.9 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 2.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 2.7 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 3.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases