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Illumina Body Map 2 (GSE30611)

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Results for LHX6

Z-value: 0.70

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Transcription factors associated with LHX6

Gene Symbol Gene ID Gene Info
ENSG00000106852.15 LIM homeobox 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX6hg38_v1_chr9_-_122213903_1222139370.355.1e-02Click!

Activity profile of LHX6 motif

Sorted Z-values of LHX6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_89010515 1.85 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr2_-_89177160 1.52 ENST00000484817.1
immunoglobulin kappa variable 2-24
chr12_-_9607903 1.40 ENST00000229402.4
killer cell lectin like receptor B1
chr2_+_90038848 1.38 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr6_-_166627244 1.24 ENST00000265678.9
ribosomal protein S6 kinase A2
chr12_-_44875647 1.13 ENST00000395487.6
neural EGFL like 2
chr3_+_108822778 1.12 ENST00000295756.11
T cell receptor associated transmembrane adaptor 1
chr2_+_90004792 1.11 ENST00000462693.1
immunoglobulin kappa variable 2D-24 (non-functional)
chr2_-_88861563 1.11 ENST00000624935.3
ENST00000390241.3
novel transcript
immunoglobulin kappa joining 2
chr12_-_44876294 1.09 ENST00000429094.7
ENST00000551601.5
ENST00000549027.5
ENST00000452445.6
neural EGFL like 2
chr14_-_103715433 1.01 ENST00000554913.5
ENST00000555055.6
ENST00000554974.5
ENST00000553361.5
ENST00000555964.5
ENST00000556682.5
ENST00000553332.5
ENST00000352127.11
X-ray repair cross complementing 3
chr21_-_14658812 0.97 ENST00000647101.1
SAM domain, SH3 domain and nuclear localization signals 1
chr4_+_1721470 0.93 ENST00000612220.5
ENST00000313288.9
transforming acidic coiled-coil containing protein 3
chr3_+_108822759 0.92 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chr4_+_77605807 0.87 ENST00000682537.1
C-X-C motif chemokine ligand 13
chr12_-_91153149 0.85 ENST00000550758.1
decorin
chr17_-_64130813 0.83 ENST00000606895.2
endoplasmic reticulum to nucleus signaling 1
chr11_+_5689691 0.81 ENST00000425490.5
tripartite motif containing 22
chr12_+_8513499 0.81 ENST00000299665.3
C-type lectin domain family 4 member D
chr19_+_49513353 0.80 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr12_-_44875468 0.80 ENST00000553120.1
neural EGFL like 2
chr5_-_111512473 0.79 ENST00000296632.8
ENST00000512160.5
ENST00000509887.5
StAR related lipid transfer domain containing 4
chr16_+_11965193 0.76 ENST00000053243.6
ENST00000396495.3
TNF receptor superfamily member 17
chr7_+_37683733 0.76 ENST00000334425.2
ENST00000450180.5
G protein-coupled receptor 141
chr14_-_100376251 0.75 ENST00000556645.5
ENST00000556209.5
ENST00000556504.5
ENST00000556435.5
ENST00000554772.5
ENST00000553581.1
ENST00000553769.6
ENST00000554605.5
ENST00000557722.5
ENST00000553413.5
ENST00000553524.5
ENST00000358655.8
tryptophanyl-tRNA synthetase 1
chr16_+_31873772 0.73 ENST00000394846.7
ENST00000300870.15
zinc finger protein 267
chrX_+_37780049 0.72 ENST00000378588.5
cytochrome b-245 beta chain
chr1_-_157820060 0.72 ENST00000491942.1
ENST00000358292.7
Fc receptor like 1
chr14_+_20781139 0.68 ENST00000304677.3
ribonuclease A family member k6
chr7_-_111784406 0.67 ENST00000664131.1
ENST00000437129.5
dedicator of cytokinesis 4
chr7_-_111784448 0.67 ENST00000450156.6
dedicator of cytokinesis 4
chr12_-_44875980 0.66 ENST00000548826.5
neural EGFL like 2
chr15_-_77420135 0.66 ENST00000560626.6
pseudopodium enriched atypical kinase 1
chr17_+_76265332 0.66 ENST00000327490.8
ENST00000587913.1
UBA like domain containing 2
chr1_-_145996567 0.66 ENST00000582401.6
thioredoxin interacting protein
chr15_-_77420087 0.64 ENST00000564328.5
ENST00000682557.1
ENST00000558305.5
pseudopodium enriched atypical kinase 1
chr1_-_92486916 0.63 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr20_+_19886506 0.60 ENST00000648440.1
Ras and Rab interactor 2
chr20_-_64049631 0.60 ENST00000340356.9
SRY-box transcription factor 18
chr1_-_157820113 0.59 ENST00000368176.8
Fc receptor like 1
chr12_+_66302486 0.59 ENST00000247815.9
DNA helicase B
chr5_-_35938572 0.58 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
calcyphosine like
chr1_+_224183197 0.57 ENST00000323699.9
delta 4-desaturase, sphingolipid 1
chr6_+_127577168 0.57 ENST00000329722.8
chromosome 6 open reading frame 58
chr16_+_55478830 0.57 ENST00000568715.5
matrix metallopeptidase 2
chr4_-_137532452 0.56 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr3_-_129428590 0.55 ENST00000503957.1
ENST00000505956.6
ENST00000326085.7
EF-hand calcium binding domain 12
chr10_+_69802424 0.55 ENST00000673802.2
ENST00000517713.5
ENST00000520133.5
ENST00000522165.5
ENST00000673641.2
ENST00000673628.2
collagen type XIII alpha 1 chain
chr3_-_41961989 0.55 ENST00000420927.5
ENST00000301831.9
ENST00000414606.1
unc-51 like kinase 4
chr19_+_17747737 0.54 ENST00000600676.5
ENST00000600209.5
ENST00000596309.5
ENST00000598539.5
ENST00000597474.5
ENST00000593385.5
ENST00000598067.5
ENST00000593833.5
FCH and mu domain containing endocytic adaptor 1
chr5_-_111512554 0.54 ENST00000505803.5
ENST00000502322.5
StAR related lipid transfer domain containing 4
chr19_+_12791470 0.53 ENST00000302754.6
JunB proto-oncogene, AP-1 transcription factor subunit
chr13_-_41019289 0.53 ENST00000239882.7
E74 like ETS transcription factor 1
chr6_+_29550407 0.53 ENST00000641137.1
olfactory receptor family 2 subfamily I member 1 pseudogene
chr7_-_87220567 0.52 ENST00000433078.5
transmembrane protein 243
chr19_+_17747698 0.52 ENST00000594202.5
ENST00000252771.11
FCH and mu domain containing endocytic adaptor 1
chr8_-_13276491 0.51 ENST00000512044.6
DLC1 Rho GTPase activating protein
chrX_+_15507302 0.51 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr15_+_51377410 0.50 ENST00000612989.1
gliomedin
chr4_-_173334385 0.50 ENST00000446922.6
high mobility group box 2
chr15_-_64381431 0.50 ENST00000558008.3
ENST00000300035.9
ENST00000559519.5
ENST00000380258.6
PCNA clamp associated factor
chr4_-_173334249 0.49 ENST00000506267.1
ENST00000296503.10
high mobility group box 2
chr14_+_21825453 0.49 ENST00000390432.2
T cell receptor alpha variable 10
chr2_-_201071579 0.49 ENST00000453765.5
ENST00000452799.5
ENST00000446678.5
ENST00000418596.7
ENST00000681958.1
family with sequence similarity 126 member B
chr4_-_46124046 0.49 ENST00000295452.5
gamma-aminobutyric acid type A receptor subunit gamma1
chr5_+_142770367 0.48 ENST00000645722.2
ENST00000274498.9
Rho GTPase activating protein 26
chr6_+_130018565 0.47 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr3_-_125055987 0.47 ENST00000311127.9
heart development protein with EGF like domains 1
chr1_+_160400543 0.47 ENST00000368061.3
VANGL planar cell polarity protein 2
chr6_+_26402237 0.46 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
butyrophilin subfamily 3 member A1
chr4_-_102828048 0.44 ENST00000508249.1
ubiquitin conjugating enzyme E2 D3
chrX_-_154097731 0.44 ENST00000628176.2
methyl-CpG binding protein 2
chr1_+_81306096 0.44 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
adhesion G protein-coupled receptor L2
chr16_+_11965234 0.44 ENST00000562385.1
TNF receptor superfamily member 17
chr19_-_40413364 0.43 ENST00000291825.11
ENST00000324001.8
periaxin
chr2_+_65227792 0.43 ENST00000260641.10
ENST00000377982.8
actin related protein 2
chr11_+_76445001 0.43 ENST00000533988.5
ENST00000524490.5
ENST00000334736.7
ENST00000533972.5
EMSY transcriptional repressor, BRCA2 interacting
chr8_+_42152946 0.43 ENST00000518421.5
ENST00000174653.3
ENST00000396926.8
ENST00000521280.5
ENST00000522288.5
adaptor related protein complex 3 subunit mu 2
chr7_-_87220520 0.42 ENST00000455575.1
transmembrane protein 243
chr1_-_204411804 0.42 ENST00000367188.5
protein phosphatase 1 regulatory subunit 15B
chr18_-_69956924 0.42 ENST00000581982.5
ENST00000280200.8
CD226 molecule
chr2_-_101308681 0.41 ENST00000295317.4
ring finger protein 149
chr21_-_42496186 0.40 ENST00000398352.3
ENST00000291536.8
radial spoke head component 1
chr6_-_62286161 0.40 ENST00000281156.5
KH RNA binding domain containing, signal transduction associated 2
chr9_+_12775012 0.40 ENST00000319264.4
leucine rich adaptor protein 1 like
chr19_+_49487510 0.39 ENST00000679106.1
ENST00000621674.4
ENST00000391857.9
ENST00000678510.1
ENST00000467825.2
ribosomal protein L13a
chr5_+_177426667 0.38 ENST00000355472.10
G protein-coupled receptor kinase 6
chr14_+_22040576 0.38 ENST00000390448.3
T cell receptor alpha variable 20
chr19_-_12722547 0.38 ENST00000592287.5
transportin 2
chr5_+_67004618 0.37 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr3_+_9397602 0.37 ENST00000402198.7
SET domain containing 5
chr12_-_21501551 0.36 ENST00000421138.6
ENST00000539672.1
ENST00000542432.5
ENST00000444129.7
ENST00000536964.5
ENST00000536240.5
ENST00000396093.7
ENST00000314748.10
RecQ like helicase
chr13_+_48256214 0.36 ENST00000650237.1
integral membrane protein 2B
chrX_-_154097668 0.36 ENST00000407218.5
ENST00000303391.11
ENST00000453960.7
methyl-CpG binding protein 2
chr3_-_180679468 0.36 ENST00000651046.1
ENST00000476379.6
coiled-coil domain containing 39
chr5_+_141484997 0.36 ENST00000617094.1
ENST00000306593.2
ENST00000610539.1
ENST00000618371.4
protocadherin gamma subfamily C, 4
chr1_-_17439657 0.35 ENST00000375436.9
regulator of chromosome condensation 2
chr12_-_56360084 0.35 ENST00000314128.9
ENST00000557235.5
ENST00000651915.1
signal transducer and activator of transcription 2
chr3_+_40457292 0.35 ENST00000338970.10
ENST00000396203.7
ENST00000416518.1
ribosomal protein L14
chr14_-_105021043 0.34 ENST00000392590.3
ENST00000336219.4
cell division cycle associated 4
chr12_+_6904962 0.34 ENST00000415834.5
ENST00000436789.5
leucine rich repeat containing 23
chr12_-_52652207 0.34 ENST00000309680.4
keratin 2
chr14_+_99481395 0.33 ENST00000389879.9
ENST00000557441.5
ENST00000555049.5
ENST00000555842.1
cyclin K
chr17_+_7407838 0.33 ENST00000302926.7
neuroligin 2
chr15_+_51377315 0.33 ENST00000558426.5
gliomedin
chr12_+_6904733 0.33 ENST00000007969.12
ENST00000622489.4
ENST00000443597.7
ENST00000323702.9
leucine rich repeat containing 23
chr19_-_51804104 0.32 ENST00000594900.1
formyl peptide receptor 1
chr18_-_23437927 0.32 ENST00000578520.5
ENST00000383233.8
transmembrane protein 241
chr19_-_12722350 0.32 ENST00000356861.9
transportin 2
chr11_+_33039996 0.32 ENST00000432887.5
ENST00000528898.1
ENST00000531632.6
t-complex 11 like 1
chr17_+_11854016 0.32 ENST00000579703.1
dynein axonemal heavy chain 9
chr4_-_7042931 0.31 ENST00000310085.6
coiled-coil domain containing 96
chr10_+_69801892 0.31 ENST00000398978.8
ENST00000645393.2
ENST00000354547.7
ENST00000674121.1
ENST00000673842.1
ENST00000520267.5
collagen type XIII alpha 1 chain
chr15_+_73926443 0.31 ENST00000261921.8
lysyl oxidase like 1
chr13_+_36432487 0.30 ENST00000255465.7
ENST00000625767.1
cyclin A1
chr4_-_120922822 0.30 ENST00000428209.6
ENST00000515109.5
ENST00000394435.2
PR/SET domain 5
chr7_+_151232464 0.29 ENST00000482173.5
ENST00000495645.5
ENST00000035307.6
chondroitin polymerizing factor 2
chr6_+_26402289 0.29 ENST00000414912.2
butyrophilin subfamily 3 member A1
chr3_-_112975018 0.28 ENST00000471858.5
ENST00000308611.8
ENST00000295863.4
CD200 receptor 1
chr17_+_39653080 0.28 ENST00000443521.1
StAR related lipid transfer domain containing 3
chr3_+_84958963 0.28 ENST00000383699.8
cell adhesion molecule 2
chr6_+_27138588 0.27 ENST00000615353.1
H4 clustered histone 9
chr3_-_157503375 0.27 ENST00000362010.7
ventricular zone expressed PH domain containing 1
chr3_-_157503339 0.27 ENST00000392833.6
ventricular zone expressed PH domain containing 1
chr3_-_105869035 0.26 ENST00000447441.6
ENST00000403724.5
ENST00000405772.5
Cbl proto-oncogene B
chr1_+_207325629 0.26 ENST00000618707.2
CD55 molecule (Cromer blood group)
chr11_+_60088657 0.26 ENST00000617306.1
ENST00000278888.8
membrane spanning 4-domains A2
chr5_-_113294895 0.26 ENST00000514701.5
ENST00000302475.8
MCC regulator of WNT signaling pathway
chr17_+_75456618 0.25 ENST00000314256.12
ENST00000582186.5
ENST00000582455.5
ENST00000581252.5
ENST00000579208.5
transmembrane protein 94
chr19_-_10010492 0.25 ENST00000264828.4
collagen type V alpha 3 chain
chr22_-_41947087 0.25 ENST00000407253.7
ENST00000215980.10
centromere protein M
chr17_-_81656532 0.24 ENST00000331056.10
phosphodiesterase 6G
chr1_+_241532370 0.24 ENST00000366559.9
ENST00000366557.8
kynurenine 3-monooxygenase
chr14_-_52069039 0.23 ENST00000216286.10
nidogen 2
chr6_+_30717433 0.23 ENST00000681435.1
tubulin beta class I
chr3_+_9397831 0.23 ENST00000682536.1
ENST00000406341.5
SET domain containing 5
chr4_+_143433491 0.23 ENST00000512843.1
GRB2 associated binding protein 1
chr6_+_30720335 0.23 ENST00000327892.13
tubulin beta class I
chr1_+_27935022 0.23 ENST00000411604.5
ENST00000373888.8
sphingomyelin phosphodiesterase acid like 3B
chr18_-_23437869 0.23 ENST00000542162.5
ENST00000582336.5
transmembrane protein 241
chr3_-_105869387 0.22 ENST00000438603.6
ENST00000443752.2
Cbl proto-oncogene B
chr9_+_1050330 0.22 ENST00000382255.7
ENST00000382251.7
ENST00000412350.6
ENST00000358146.7
doublesex and mab-3 related transcription factor 2
chr22_-_41946688 0.22 ENST00000404067.5
ENST00000402338.5
centromere protein M
chr19_-_19192122 0.22 ENST00000444486.7
ENST00000514819.7
ENST00000585679.1
ENST00000462790.8
myocyte enhancer factor 2B
BORCS8-MEF2B readthrough
BLOC-1 related complex subunit 8
chr3_-_105868964 0.21 ENST00000394030.8
Cbl proto-oncogene B
chr2_-_74178802 0.21 ENST00000396049.5
MOB kinase activator 1A
chr3_-_183400538 0.21 ENST00000640043.1
MCF.2 cell line derived transforming sequence-like 2
chr14_+_22202561 0.21 ENST00000390460.1
T cell receptor alpha variable 26-2
chr3_+_130443484 0.20 ENST00000512482.1
collagen type VI alpha 5 chain
chr2_-_27380715 0.20 ENST00000323703.11
ENST00000436006.1
zinc finger protein 513
chr2_+_65228122 0.20 ENST00000542850.2
actin related protein 2
chr17_-_46579651 0.20 ENST00000573185.5
ENST00000570550.5
ENST00000445552.6
ENST00000329240.10
ENST00000622488.6
ENST00000336125.6
ADP ribosylation factor like GTPase 17A
chr19_+_41363989 0.20 ENST00000413014.6
transmembrane protein 91
chr12_+_64405046 0.20 ENST00000540203.5
exportin for tRNA
chr17_-_76737321 0.20 ENST00000359995.10
ENST00000508921.7
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
serine and arginine rich splicing factor 2
chr2_-_88861920 0.19 ENST00000390242.2
immunoglobulin kappa joining 1
chr10_+_69269984 0.19 ENST00000436817.6
ENST00000450646.6
ENST00000360289.6
ENST00000448642.6
ENST00000464803.6
hexokinase 1
chr13_-_75537805 0.19 ENST00000626103.1
ENST00000682242.1
ENST00000355801.4
COMM domain containing 6
chr3_+_121835197 0.19 ENST00000273668.7
ENST00000451944.2
ELL associated factor 2
chr12_+_21501780 0.19 ENST00000229314.10
ENST00000542038.5
ENST00000540141.5
ENST00000631252.2
golgi transport 1B
chr3_-_157503574 0.19 ENST00000494677.5
ENST00000468233.5
ventricular zone expressed PH domain containing 1
chr10_+_123154364 0.19 ENST00000368859.6
ENST00000368865.9
BUB3 mitotic checkpoint protein
chr19_+_19192229 0.19 ENST00000421262.7
ENST00000456252.7
ENST00000303088.9
ENST00000593273.5
regulatory factor X associated ankyrin containing protein
chr4_-_175812236 0.18 ENST00000505375.5
glycoprotein M6A
chr2_-_88861258 0.18 ENST00000390240.2
immunoglobulin kappa joining 3
chr7_+_151086466 0.18 ENST00000397238.7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr10_-_97687191 0.18 ENST00000370626.4
arginine vasopressin induced 1
chr17_-_46361718 0.17 ENST00000575960.5
ENST00000575698.5
ENST00000571246.5
ENST00000434041.6
ENST00000656849.1
ENST00000570618.5
ENST00000450673.4
ENST00000622877.4
ADP ribosylation factor like GTPase 17B
chr14_+_59920135 0.17 ENST00000570145.1
leucine rich repeat containing 9
chrX_-_24672654 0.17 ENST00000379145.5
phosphate cytidylyltransferase 1, choline, beta
chr2_+_108588286 0.17 ENST00000332345.10
LIM zinc finger domain containing 1
chr14_-_52069228 0.17 ENST00000617139.4
nidogen 2
chr3_-_120094571 0.17 ENST00000677903.1
glycogen synthase kinase 3 beta
chr6_-_84764581 0.17 ENST00000369663.10
T-box transcription factor 18
chr17_+_68515399 0.17 ENST00000588188.6
protein kinase cAMP-dependent type I regulatory subunit alpha
chr3_+_107599309 0.16 ENST00000406780.5
BBX high mobility group box domain containing
chr6_-_24809798 0.16 ENST00000562221.1
novel protein
chr1_-_48400826 0.16 ENST00000371841.1
spermatogenesis associated 6
chr17_+_82458649 0.16 ENST00000345415.11
ENST00000412079.6
ENST00000457415.7
ENST00000584411.5
ENST00000577432.5
nuclear prelamin A recognition factor
chr13_+_33016415 0.16 ENST00000380099.4
klotho
chr18_+_62523385 0.16 ENST00000588676.1
zinc finger CCHC-type containing 2
chrX_+_101098165 0.16 ENST00000684367.1
ENST00000423383.3
ENST00000682304.1
ENST00000682095.1
ENST00000403304.6
ENST00000435570.1
centromere protein I
chr17_+_82458174 0.15 ENST00000579198.5
ENST00000390006.8
ENST00000580296.5
nuclear prelamin A recognition factor
chr4_+_176319942 0.15 ENST00000503362.2
signal peptidase complex subunit 3
chr17_-_81683659 0.15 ENST00000574938.5
ENST00000570561.5
ENST00000573392.5
ENST00000576135.5
ENST00000573715.2
ADP ribosylation factor like GTPase 16
chr4_+_143391506 0.15 ENST00000509992.1
GRB2 associated binding protein 1
chr7_+_21543020 0.15 ENST00000409508.8
ENST00000620169.4
ENST00000328843.10
dynein axonemal heavy chain 11
chr17_+_44070729 0.15 ENST00000269097.9
glucose-6-phosphatase catalytic subunit 3
chr9_-_125143457 0.14 ENST00000373549.8
ENST00000336505.11
suppressor of cancer cell invasion
chr19_+_50329637 0.14 ENST00000600355.5
nuclear receptor subfamily 1 group H member 2
chr16_+_53886883 0.14 ENST00000431610.6
ENST00000460382.5
FTO alpha-ketoglutarate dependent dioxygenase
chr11_-_125111708 0.14 ENST00000531909.5
ENST00000529530.1
transmembrane protein 218
chr5_-_147906530 0.14 ENST00000318315.5
ENST00000515291.1
chromosome 5 open reading frame 46
chr9_-_4666347 0.14 ENST00000381890.9
ENST00000682582.1
spermatogenesis associated 6 like
chr2_-_74391780 0.14 ENST00000421392.1
ENST00000437375.1
dynactin subunit 1
chr19_-_41364119 0.13 ENST00000243578.8
B9 domain containing 2
chr17_-_75941035 0.13 ENST00000586717.5
Fas binding factor 1
chr6_-_138512493 0.13 ENST00000533765.1
NHS like 1
chr9_-_4666495 0.13 ENST00000475086.5
spermatogenesis associated 6 like
chr3_+_172750959 0.13 ENST00000366254.2
ENST00000415665.5
ENST00000438041.5
epithelial cell transforming 2

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0010877 lipid transport involved in lipid storage(GO:0010877)
0.3 1.0 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.3 2.0 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 0.8 GO:1990579 protein trans-autophosphorylation(GO:0036290) peptidyl-serine trans-autophosphorylation(GO:1990579)
0.3 0.8 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2 0.7 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2 0.9 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.2 0.6 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.2 0.8 GO:0009405 pathogenesis(GO:0009405)
0.2 3.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.2 1.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 0.5 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.5 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.6 GO:0048865 stem cell fate commitment(GO:0048865) endocardium formation(GO:0060214)
0.1 0.5 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 0.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.6 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.3 GO:0018277 protein deamination(GO:0018277)
0.1 0.4 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 0.3 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 1.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.2 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.2 GO:0061055 myotome development(GO:0061055)
0.1 0.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.6 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.3 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.1 GO:0090108 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.0 0.4 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.4 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.3 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.5 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 1.0 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.1 GO:0060003 response to iron(III) ion(GO:0010041) copper ion export(GO:0060003)
0.0 0.4 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 5.9 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.2 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339) negative regulation of type B pancreatic cell development(GO:2000077)
0.0 0.7 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.7 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.1 GO:0033320 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.0 0.6 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.3 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 1.3 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091)
0.0 0.9 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 1.2 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.7 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.6 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.0 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.2 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.3 0.8 GO:1990332 Ire1 complex(GO:1990332)
0.2 0.5 GO:0060187 cell pole(GO:0060187)
0.1 0.4 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1 1.0 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.3 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.1 0.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0097452 GAIT complex(GO:0097452)
0.0 0.6 GO:0030478 actin cap(GO:0030478)
0.0 0.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.8 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 1.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.0 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.0 0.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 1.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.2 0.8 GO:0019770 IgG receptor activity(GO:0019770)
0.2 0.6 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.2 0.6 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.2 0.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.5 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 0.8 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 0.4 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 2.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 1.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 1.6 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.0 0.3 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.1 GO:0070975 FHA domain binding(GO:0070975)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0043682 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.0 0.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 2.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.0 4.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 2.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 4.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.9 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 1.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids