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Illumina Body Map 2 (GSE30611)

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Results for MAFA

Z-value: 0.98

Motif logo

Transcription factors associated with MAFA

Gene Symbol Gene ID Gene Info
ENSG00000182759.4 MAF bZIP transcription factor A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAFAhg38_v1_chr8_-_143430727_1434307330.029.1e-01Click!

Activity profile of MAFA motif

Sorted Z-values of MAFA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_122371014 2.65 ENST00000362012.7
prostaglandin-endoperoxide synthase 1
chr21_+_39867387 2.44 ENST00000328619.10
Purkinje cell protein 4
chr1_+_163069353 2.31 ENST00000531057.5
ENST00000527809.5
ENST00000367908.8
ENST00000367909.11
regulator of G protein signaling 4
chr10_-_77637721 2.23 ENST00000638848.1
ENST00000639406.1
ENST00000618048.2
ENST00000639120.1
ENST00000640834.1
ENST00000639601.1
ENST00000638514.1
ENST00000457953.6
ENST00000639090.1
ENST00000639489.1
ENST00000372440.6
ENST00000404771.8
ENST00000638203.1
ENST00000638306.1
ENST00000638351.1
ENST00000638606.1
ENST00000639591.1
ENST00000640182.1
ENST00000640605.1
ENST00000640141.1
potassium calcium-activated channel subfamily M alpha 1
chr9_+_122371036 2.12 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
prostaglandin-endoperoxide synthase 1
chr10_-_77637444 2.04 ENST00000639205.1
ENST00000639498.1
ENST00000372408.7
ENST00000372403.9
ENST00000640626.1
ENST00000404857.6
ENST00000638252.1
ENST00000640029.1
ENST00000640934.1
ENST00000639823.1
ENST00000372437.6
ENST00000639344.1
potassium calcium-activated channel subfamily M alpha 1
chrX_-_93673558 1.98 ENST00000475430.2
ENST00000373079.4
nucleosome assembly protein 1 like 3
chr10_-_77637902 1.82 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
potassium calcium-activated channel subfamily M alpha 1
chr15_+_80404320 1.78 ENST00000303329.9
ENST00000622346.4
aryl hydrocarbon receptor nuclear translocator 2
chr2_-_25982471 1.75 ENST00000264712.8
kinesin family member 3C
chr12_-_22334683 1.70 ENST00000404299.3
ENST00000396037.9
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr10_-_77637789 1.65 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
potassium calcium-activated channel subfamily M alpha 1
chr6_-_99349647 1.52 ENST00000389677.6
failed axon connections homolog, metaxin like GST domain containing
chr9_-_127950716 1.50 ENST00000373084.8
family with sequence similarity 102 member A
chr2_-_25982681 1.35 ENST00000405914.1
kinesin family member 3C
chr15_-_82647336 1.34 ENST00000617522.4
ENST00000684509.1
cytoplasmic polyadenylation element binding protein 1
chr22_+_22375984 1.22 ENST00000390296.2
immunoglobulin lambda variable 5-45
chr7_-_135728177 1.21 ENST00000682651.1
ENST00000354042.8
solute carrier family 13 member 4
chr10_-_77637633 1.14 ENST00000638223.1
ENST00000639544.1
ENST00000640807.1
ENST00000434208.6
ENST00000626620.3
ENST00000638575.1
ENST00000638759.1
potassium calcium-activated channel subfamily M alpha 1
chr1_+_202122910 1.10 ENST00000682545.1
ENST00000367282.6
ENST00000682887.1
G protein-coupled receptor 37 like 1
chrX_-_153875847 1.08 ENST00000361699.8
ENST00000361981.7
L1 cell adhesion molecule
chr10_-_29522527 1.04 ENST00000632315.1
supervillin
chr22_+_22720615 1.03 ENST00000390309.2
immunoglobulin lambda variable 3-19
chr7_-_149126306 0.95 ENST00000483014.1
ENST00000378061.7
zinc finger protein 425
chr16_+_56191476 0.95 ENST00000262493.12
G protein subunit alpha o1
chr2_+_114442616 0.94 ENST00000410059.6
dipeptidyl peptidase like 10
chr7_+_150379316 0.93 ENST00000483664.5
ENST00000329630.10
novel transcript
zinc finger protein 775
chr11_+_107591077 0.92 ENST00000531234.5
ENST00000265840.12
ELMO domain containing 1
chr12_+_108131740 0.90 ENST00000332082.8
WSC domain containing 2
chr22_+_22409755 0.88 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr9_-_28670285 0.88 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
leucine rich repeat and Ig domain containing 2
chr3_-_196712194 0.88 ENST00000399942.4
ENST00000409690.5
centrosomal protein 19
chr11_+_111540659 0.87 ENST00000375615.7
ENST00000525126.5
ENST00000375614.7
ENST00000533265.5
layilin
chr11_+_107591222 0.81 ENST00000443271.2
ELMO domain containing 1
chr10_-_77637558 0.80 ENST00000372421.10
ENST00000639370.1
ENST00000640773.1
ENST00000638895.1
potassium calcium-activated channel subfamily M alpha 1
chrX_-_72943837 0.80 ENST00000615063.2
DMRT like family C1
chr3_+_35639515 0.79 ENST00000684406.1
cAMP regulated phosphoprotein 21
chr1_+_65992389 0.77 ENST00000423207.6
phosphodiesterase 4B
chr17_-_17206264 0.76 ENST00000321560.4
phospholipase D family member 6
chr3_+_35639589 0.76 ENST00000428373.5
cAMP regulated phosphoprotein 21
chr1_+_174799895 0.74 ENST00000489615.5
RAB GTPase activating protein 1 like
chr19_+_35031263 0.73 ENST00000640135.1
ENST00000596348.2
sodium voltage-gated channel beta subunit 1
chr19_+_42313374 0.73 ENST00000598766.1
ENST00000673187.1
transmembrane protein 145
chr17_+_18856299 0.73 ENST00000432893.6
ENST00000610773.4
ENST00000414602.5
ENST00000574522.5
ENST00000570450.5
ENST00000419071.6
phosphoribosyl pyrophosphate synthetase associated protein 2
chr6_+_147204405 0.72 ENST00000546097.5
ENST00000367481.7
syntaxin binding protein 5
chr12_+_56152579 0.71 ENST00000551834.5
ENST00000552568.5
myosin light chain 6B
chr10_+_25174796 0.70 ENST00000650135.1
G protein-coupled receptor 158
chr22_+_22327298 0.66 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr5_+_177426701 0.66 ENST00000507633.5
ENST00000393576.7
ENST00000355958.9
ENST00000528793.5
ENST00000512684.1
G protein-coupled receptor kinase 6
chr12_-_132144302 0.66 ENST00000397333.4
DEAD-box helicase 51
chr1_-_45491150 0.66 ENST00000372086.4
testis associated actin remodelling kinase 2
chr3_+_196712298 0.65 ENST00000392391.9
ENST00000296333.10
phosphatidylinositol glycan anchor biosynthesis class X
chr19_+_42313298 0.64 ENST00000301204.8
ENST00000673205.1
transmembrane protein 145
chr7_-_151057848 0.64 ENST00000297518.4
cyclin dependent kinase 5
chr7_-_151057880 0.63 ENST00000485972.6
cyclin dependent kinase 5
chr5_-_22853320 0.62 ENST00000504376.6
ENST00000382254.6
cadherin 12
chr11_+_111541326 0.62 ENST00000530962.5
ENST00000528924.4
layilin
chr8_-_7056729 0.61 ENST00000330590.4
defensin alpha 5
chr16_+_28985251 0.60 ENST00000360872.9
ENST00000566177.5
linker for activation of T cells
chrX_+_72776873 0.59 ENST00000334036.10
DMRT like family C1B
chr11_+_24497155 0.59 ENST00000529015.5
ENST00000533227.5
leucine zipper protein 2
chr16_+_28985043 0.59 ENST00000395456.7
ENST00000564277.5
ENST00000630764.2
ENST00000354453.7
linker for activation of T cells
chr17_+_27609836 0.59 ENST00000582410.5
kinase suppressor of ras 1
chr2_+_190880809 0.58 ENST00000320717.8
glutaminase
chr14_+_90397019 0.58 ENST00000447653.8
ENST00000356978.9
ENST00000626705.2
calmodulin 1
chr14_+_90397056 0.57 ENST00000553542.5
calmodulin 1
chr19_+_35666515 0.57 ENST00000617999.4
ENST00000616789.4
uroplakin 1A
chr22_+_22818994 0.56 ENST00000390316.2
immunoglobulin lambda variable 3-9
chrX_-_53281609 0.56 ENST00000638630.1
ENST00000375365.2
IQ motif and Sec7 domain ArfGEF 2
chr22_+_22369601 0.54 ENST00000390295.3
immunoglobulin lambda variable 7-46
chr19_+_12838437 0.53 ENST00000251472.9
microtubule associated serine/threonine kinase 1
chr19_-_37467380 0.53 ENST00000316950.11
ENST00000591710.5
zinc finger protein 569
chr16_-_68371005 0.52 ENST00000574662.1
sphingomyelin phosphodiesterase 3
chrX_-_53281566 0.52 ENST00000638583.1
ENST00000639161.2
ENST00000485377.5
IQ motif and Sec7 domain ArfGEF 2
chr11_+_118956289 0.52 ENST00000264031.3
uroplakin 2
chr12_-_22334637 0.51 ENST00000381424.3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr8_-_88327475 0.50 ENST00000286614.11
matrix metallopeptidase 16
chr10_+_25174969 0.49 ENST00000376351.4
G protein-coupled receptor 158
chr19_-_49961081 0.49 ENST00000426971.2
ENST00000447370.6
sialic acid binding Ig like lectin 11
chrX_-_53281524 0.48 ENST00000498281.2
IQ motif and Sec7 domain ArfGEF 2
chr9_+_137139139 0.48 ENST00000371561.8
glutamate ionotropic receptor NMDA type subunit 1
chr8_-_131040890 0.46 ENST00000286355.10
adenylate cyclase 8
chr9_+_128787331 0.46 ENST00000223865.8
TBC1 domain family member 13
chr1_-_190477854 0.44 ENST00000367462.5
BMP/retinoic acid inducible neural specific 3
chr17_-_49848017 0.44 ENST00000326219.5
ENST00000334568.8
ENST00000352793.6
ENST00000398154.5
ENST00000436235.5
tachykinin precursor 4
chr18_-_2982873 0.43 ENST00000584915.1
lipin 2
chr1_+_156154371 0.42 ENST00000368282.1
semaphorin 4A
chr17_+_40309189 0.40 ENST00000577646.5
retinoic acid receptor alpha
chr19_+_53538415 0.39 ENST00000648122.1
zinc finger protein 331
chr16_+_1309136 0.39 ENST00000325437.9
ubiquitin conjugating enzyme E2 I
chr19_-_50637939 0.38 ENST00000338916.8
synaptotagmin 3
chr1_+_224616302 0.36 ENST00000272133.4
cornichon family AMPA receptor auxiliary protein 3
chr11_+_24496988 0.36 ENST00000336930.11
leucine zipper protein 2
chrX_-_66639022 0.35 ENST00000374719.8
ectodysplasin A2 receptor
chr5_-_39270623 0.34 ENST00000512138.1
ENST00000646045.2
FYN binding protein 1
chr3_+_75906666 0.34 ENST00000487694.7
ENST00000602589.5
roundabout guidance receptor 2
chr6_+_147204525 0.34 ENST00000321680.10
ENST00000367480.7
syntaxin binding protein 5
chr3_+_141402322 0.33 ENST00000510338.5
ENST00000504673.5
zinc finger and BTB domain containing 38
chr5_+_139293728 0.33 ENST00000510056.5
ENST00000511249.5
ENST00000394805.8
ENST00000503811.5
ENST00000618441.5
matrin 3
chr5_+_139293700 0.32 ENST00000504045.5
ENST00000504311.5
ENST00000502499.5
matrin 3
chr10_-_48493641 0.31 ENST00000417247.6
Rho GTPase activating protein 22
chrX_-_66639255 0.31 ENST00000451436.6
ectodysplasin A2 receptor
chr1_+_77888490 0.31 ENST00000401035.7
ENST00000330010.12
nexilin F-actin binding protein
chr22_-_30266839 0.30 ENST00000403463.1
ENST00000215781.3
oncostatin M
chr5_+_139293660 0.30 ENST00000512876.5
ENST00000513678.5
matrin 3
chr6_+_42929127 0.29 ENST00000394142.7
canopy FGF signaling regulator 3
chr6_-_73521783 0.29 ENST00000331523.7
ENST00000356303.7
eukaryotic translation elongation factor 1 alpha 1
chr8_+_23288081 0.28 ENST00000265806.12
ENST00000519952.6
ENST00000518840.6
R3H domain and coiled-coil containing 1
chr16_-_67481079 0.28 ENST00000565835.5
ENST00000602876.5
ENST00000540149.5
ATPase H+ transporting V0 subunit d1
chr5_+_139293939 0.27 ENST00000508689.1
ENST00000514528.5
matrin 3
chr15_-_82647123 0.27 ENST00000569257.5
cytoplasmic polyadenylation element binding protein 1
chr7_-_99919479 0.26 ENST00000354241.5
tripartite motif containing 4
chr5_+_177087412 0.26 ENST00000513166.1
fibroblast growth factor receptor 4
chr16_-_21857418 0.26 ENST00000415645.6
nuclear pore complex interacting protein family member B4
chr6_+_96924720 0.24 ENST00000369261.9
kelch like family member 32
chr22_-_30546682 0.24 ENST00000402034.6
SEC14 like lipid binding 6
chr1_-_216805367 0.24 ENST00000360012.7
estrogen related receptor gamma
chr14_+_50312311 0.23 ENST00000426751.7
ENST00000311459.12
ENST00000672419.1
ENST00000672910.1
ENST00000557421.7
ENST00000245448.11
ENST00000554204.7
distal membrane arm assembly complex 2 like
chr7_-_108528155 0.22 ENST00000453085.1
patatin like phospholipase domain containing 8
chrX_-_47650488 0.22 ENST00000247161.7
ENST00000376983.8
ENST00000343894.8
ETS transcription factor ELK1
chr12_+_53423849 0.21 ENST00000257863.9
ENST00000550311.5
ENST00000379791.7
anti-Mullerian hormone receptor type 2
chr7_+_74657745 0.20 ENST00000614986.4
ENST00000620879.4
ENST00000621734.4
general transcription factor IIi
chr8_+_84183534 0.20 ENST00000518566.5
RALY RNA binding protein like
chr7_+_135557904 0.20 ENST00000285968.11
nucleoporin 205
chr16_+_28638065 0.20 ENST00000683297.1
nuclear pore complex interacting protein family member B8
chr1_+_77888612 0.19 ENST00000334785.12
nexilin F-actin binding protein
chr19_+_35612729 0.19 ENST00000203166.10
HAUS augmin like complex subunit 5
chr7_-_87220567 0.18 ENST00000433078.5
transmembrane protein 243
chr2_+_190880834 0.18 ENST00000338435.8
glutaminase
chr7_+_129126518 0.16 ENST00000467614.2
novel protein similar to mitogen-activated protein kinase kinase 2 MAP2K2
chr1_-_153312919 0.15 ENST00000683862.1
peptidoglycan recognition protein 3
chr15_-_89912882 0.14 ENST00000398333.7
ENST00000357484.10
ARPIN-AP3S2 readthrough
actin related protein 2/3 complex inhibitor
chr7_-_22500152 0.13 ENST00000406890.6
ENST00000678116.1
ENST00000424363.5
STEAP family member 1B
chr7_-_135211313 0.12 ENST00000682802.1
ENST00000683848.1
ENST00000354475.5
WD repeat domain 91
chr7_+_152025632 0.12 ENST00000430044.7
ENST00000431668.1
ENST00000446096.5
ENST00000423337.5
polypeptide N-acetylgalactosaminyltransferase 11
chr9_-_128127711 0.12 ENST00000449878.1
ENST00000338961.11
ENST00000678174.1
prostaglandin E synthase 2
chr14_+_80955577 0.12 ENST00000642209.1
ENST00000298171.7
thyroid stimulating hormone receptor
chr4_+_2469068 0.11 ENST00000541204.5
ENST00000502316.5
ENST00000507247.5
ENST00000509258.5
ENST00000314289.13
ENST00000511859.5
ring finger protein 4
chr14_+_24136152 0.11 ENST00000559123.5
ENST00000206451.11
ENST00000382708.7
ENST00000561435.5
proteasome activator subunit 1
chr2_+_53971072 0.11 ENST00000422521.2
ENST00000607452.6
acylphosphatase 2
chrX_-_153875979 0.11 ENST00000407935.6
ENST00000439496.5
L1 cell adhesion molecule
chr3_+_185586270 0.11 ENST00000296257.10
SUMO specific peptidase 2
chr14_+_32934383 0.11 ENST00000551634.6
neuronal PAS domain protein 3
chr16_-_67481131 0.10 ENST00000290949.8
ATPase H+ transporting V0 subunit d1
chr1_-_31937769 0.10 ENST00000649841.1
ENST00000534796.5
protein tyrosine phosphatase 4A2
chr4_-_10116724 0.10 ENST00000502702.5
WD repeat domain 1
chr17_+_40309161 0.10 ENST00000254066.10
retinoic acid receptor alpha
chr4_+_6782674 0.09 ENST00000307659.6
ENST00000425103.5
KIAA0232
chr14_+_35826298 0.09 ENST00000216807.12
BRMS1 like transcriptional repressor
chr12_-_105084439 0.09 ENST00000258494.14
aldehyde dehydrogenase 1 family member L2
chr1_+_42767241 0.09 ENST00000372525.7
chromosome 1 open reading frame 50
chr3_-_49786194 0.09 ENST00000613416.4
inositol hexakisphosphate kinase 1
chrX_+_75274060 0.08 ENST00000373383.9
ENST00000373379.5
uracil phosphoribosyltransferase homolog
chr3_+_52388883 0.07 ENST00000480649.1
dynein axonemal heavy chain 1
chr1_-_31938302 0.06 ENST00000647444.2
protein tyrosine phosphatase 4A2
chr20_+_325536 0.06 ENST00000342665.5
SRY-box transcription factor 12
chr8_-_113377125 0.06 ENST00000343508.7
CUB and Sushi multiple domains 3
chr19_+_39156631 0.06 ENST00000599657.5
p21 (RAC1) activated kinase 4
chr2_+_114442299 0.06 ENST00000436732.5
dipeptidyl peptidase like 10
chr3_-_49786508 0.05 ENST00000395238.5
ENST00000468463.5
ENST00000321599.9
ENST00000460540.1
inositol hexakisphosphate kinase 1
chr21_+_18244828 0.04 ENST00000299295.7
chondrolectin
chr3_-_132017749 0.04 ENST00000514999.5
copine 4
chr5_-_179858797 0.04 ENST00000520698.5
ENST00000518235.5
ENST00000376931.6
ENST00000518219.5
ENST00000292586.11
ENST00000521333.5
ENST00000523084.5
MRN complex interacting protein
chr15_-_66565959 0.04 ENST00000537670.5
lactase like
chr4_+_73740541 0.03 ENST00000401931.1
ENST00000307407.8
C-X-C motif chemokine ligand 8
chr1_-_203175783 0.03 ENST00000621380.1
ENST00000255416.9
myosin binding protein H
chr19_-_47231191 0.03 ENST00000439096.3
BCL2 binding component 3
chr22_+_40679273 0.03 ENST00000381433.2
melanin concentrating hormone receptor 1
chr1_+_77888645 0.02 ENST00000440324.5
nexilin F-actin binding protein
chr21_+_44600597 0.02 ENST00000609664.2
keratin associated protein 10-7
chr14_-_50312212 0.02 ENST00000555423.5
ENST00000267436.9
ENST00000421284.7
L-2-hydroxyglutarate dehydrogenase
chr16_-_66873233 0.02 ENST00000561579.6
NEDD8 activating enzyme E1 subunit 1
chr10_-_117138264 0.00 ENST00000369206.6
ventral anterior homeobox 1
chr17_-_78132407 0.00 ENST00000322914.7
transmembrane channel like 6

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.7 GO:0034465 response to carbon monoxide(GO:0034465)
0.3 0.8 GO:0007308 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.2 4.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 1.4 GO:0019236 response to pheromone(GO:0019236)
0.2 0.5 GO:0043449 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.1 1.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.7 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.8 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 1.1 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 0.4 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.1 0.4 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.5 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 1.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.3 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.1 1.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:0032827 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 3.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 2.0 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 2.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.7 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 1.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.9 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 2.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 2.8 GO:0002377 immunoglobulin production(GO:0002377)
0.0 1.0 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 1.2 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 1.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.6 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.5 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 1.7 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 1.6 GO:0030449 regulation of complement activation(GO:0030449)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 0.7 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.4 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.1 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 9.7 GO:0005901 caveola(GO:0005901)
0.0 1.0 GO:0036449 microtubule minus-end(GO:0036449)
0.0 3.1 GO:0097542 ciliary tip(GO:0097542)
0.0 1.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 4.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 9.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
1.0 4.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.4 1.3 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.4 1.1 GO:0036505 prosaposin receptor activity(GO:0036505)
0.2 2.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 0.5 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.7 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.7 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.4 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.8 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 2.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.5 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 3.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 3.5 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 REACTOME KINESINS Genes involved in Kinesins
0.1 0.9 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 1.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 4.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 2.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling